Biaoru Li

Senior Research Scientist

  • 585 Citations
  • 16 h-Index
19942019

Research output per year

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Research Output

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2019

Conjugate prodrug AN-233 induces fetal hemoglobin expression in sickle erythroid progenitors and β-YAC transgenic mice

Oseghale, A. R., Zhu, X., Li, B., Peterson, K. R., Nudelman, A., Rephaeli, A., Xu, H. & Pace, B. S., Nov 2019, In : Blood Cells, Molecules, and Diseases. 79, 102345.

Research output: Contribution to journalArticle

1 Scopus citations

MIR-144-mediated NRF2 gene silencing inhibits fetal hemoglobin expression in sickle cell disease

Li, B., Zhu, X., Ward, C. M., Starlard-Davenport, A., Takezaki, M., Berry, A., Ward, A., Wilder, C., Neunert, C., Kutlar, A. & Pace, B. S., Feb 2019, In : Experimental Hematology. 70, p. 85-96.e5

Research output: Contribution to journalArticle

11 Scopus citations

MIR29B mediates epigenetic mechanisms of HBG gene activation

Starlard-Davenport, A., Smith, A., Vu, L., Li, B. & Pace, B. S., Jul 2019, In : British Journal of Haematology. 186, 1, p. 91-100 10 p.

Research output: Contribution to journalArticle

1 Scopus citations
2016

Original Research: Stable expression of miR-34a mediates fetal hemoglobin induction in K562 cells

Ward, C. M., Li, B. & Pace, B. S., 2016, In : Experimental Biology and Medicine. 241, 7, p. 719-729 11 p.

Research output: Contribution to journalArticle

8 Scopus citations
2015

Cell signaling pathways involved in drug-mediated fetal hemoglobin induction: Strategies to treat sickle cell disease

Pace, B. S., Liu, L., Li, B. & Makala, L. H., Aug 19 2015, In : Experimental Biology and Medicine. 240, 8, p. 1050-1064 15 p.

Research output: Contribution to journalArticle

14 Scopus citations

Novel inducers of fetal globin identified through high throughput screening (HTS) are active in vivo in anemic baboons and transgenic mice

Boosalis, M. S., Sangerman, J. I., White, G. L., Wolf, R. F., Shen, L., Dai, Y., White, E., Makala, L. H., Li, B., Pace, B. S., Nouraie, M., Faller, D. V. & Perrine, S. P., Dec 1 2015, In : PloS one. 10, 12, 0144660.

Research output: Contribution to journalArticle

7 Scopus citations
2014

A cell-based high-throughput screen for novel chemical inducers of fetal hemoglobin for treatment of hemoglobinopathies

Peterson, K. R., Costa, F. C., Fedosyuk, H., Neades, R. Y., Chazelle, A. M., Zelenchuk, L., Fonteles, A. H., Dalal, P., Roy, A., Chaguturu, R., Li, B. & Pace, B. S., Sep 16 2014, In : PloS one. 9, 9, e107006.

Research output: Contribution to journalArticle

17 Scopus citations

Characterization of transcription factor networks involved in umbilical cord blood CD34+ stem cells-derived erythropoiesis

Li, B., Ding, L., Yang, C., Kang, B., Liu, L., Story, M. D. & Pace, B. S., Sep 2014, In : PloS one. 9, 9, e0107133.

Research output: Contribution to journalArticle

5 Scopus citations
21 Scopus citations
2012

Characterization of the transcriptome profiles related to globin gene switching during in vitro erythroid maturation

Li, B., Ding, L., Li, W., Story, M. D. & Pace, B. S., Apr 26 2012, In : BMC Genomics. 13, 1, 153.

Research output: Contribution to journalArticle

13 Scopus citations
2009

Genomic expression analysis by single-cell mRNA differential display of quiescent CD8 T cells from tumour-infiltrating lymphocytes obtained from in vivo liver tumours

Zhang, W., Ding, J., Qu, Y., Hu, H., Lin, M., Datta, A., Larson, A., Liu, G. E. & Li, B., May 2009, In : Immunology. 127, 1, p. 83-90 8 p.

Research output: Contribution to journalArticle

4 Scopus citations
2006

Regulation of sexual dimorphism: Mutational and chemogenetic analysis of the doublesex DM domain

Zhang, W., Li, B., Singh, R., Narendra, U., Zhu, L. & Weiss, M. A., Jan 2006, In : Molecular and Cellular Biology. 26, 2, p. 535-547 13 p.

Research output: Contribution to journalArticle

18 Scopus citations

SRY-directed DNA Bending and Human Sex Reversal: Reassessment of a Clinical Mutation Uncovers a Global Coupling between the HMG Box and its Tail

Li, B., Phillips, N. B., Jancso-Radek, A., Ittah, V., Singh, R., Jones, D. N., Haas, E. & Weiss, M. A., Jul 7 2006, In : Journal of Molecular Biology. 360, 2, p. 310-328 19 p.

Research output: Contribution to journalArticle

16 Scopus citations
2004

Enhancing the activity of insulin at the receptor interface: Crystal structure and photo-cross-linking of A8 analogues

Wan, Z., Xu, B., Huang, K., Chu, Y. C., Li, B., Nakagawa, S. H., Qu, Y., Hu, S. Q., Katsoyannis, P. G. & Weiss, M. A., Dec 28 2004, In : Biochemistry. 43, 51, p. 16119-16133 15 p.

Research output: Contribution to journalArticle

27 Scopus citations

Expression, crystallization and preliminary X-ray characterization of the Drosophila transcription factor Doublesex

Bayrer, J., Wan, Z., Li, B. & Weiss, M. A., Jul 2004, In : Acta Crystallographica Section D: Biological Crystallography. 60, 7, p. 1328-1330 3 p.

Research output: Contribution to journalArticle

2 Scopus citations

How insulin binds: The B-chain α-helix contacts the L1 β-helix of the insulin receptor

Huang, K., Xu, B., Hu, S. Q., Chu, Y. C., Hua, Q. X., Qu, Y., Li, B., Wang, S., Wang, R. Y., Nakagawa, S. H., Theede, A. M., Whittaker, J., De Meyts, P., Katsoyannis, P. G. & Weiss, M. A., Aug 6 2004, In : Journal of Molecular Biology. 341, 2, p. 529-550 22 p.

Research output: Contribution to journalArticle

69 Scopus citations
2003

DNA alterations in human aberrant crypt foci and colon cancers by random primed polymerase chain reaction

Luo, L., Li, B. & Pretlow, T. P., Oct 1 2003, In : Cancer Research. 63, 19, p. 6166-6169 4 p.

Research output: Contribution to journalArticle

31 Scopus citations
2002

Experimental and bioinformatics comparison of gene expression between T cells from TIL of liver cancer and T cells from UniGene

Li, B., Perabekam, S., Liu, G., Yin, M., Song, S. & Larson, A., May 21 2002, In : Journal of Gastroenterology. 37, 4, p. 275-282 8 p.

Research output: Contribution to journalArticle

10 Scopus citations

Sex-specific gene regulation: The doublesex DM motif is a bipartite DNA-binding domain

Narendra, U., Zhu, L., Li, B., Wilken, J. & Weiss, M. A., Nov 8 2002, In : Journal of Biological Chemistry. 277, 45, p. 43463-43473 11 p.

Research output: Contribution to journalArticle

22 Scopus citations
2001

Alterations in IRF1/IRF2 expression in acute myelogenous leukemia

Preisler, H. D., Perambakam, S., Li, B., Hsu, W. T., Venugopal, P., Creech, S., Sivaraman, S. & Tanaka, N., Aug 23 2001, In : American Journal of Hematology. 68, 1, p. 23-31 9 p.

Research output: Contribution to journalArticle

18 Scopus citations

Human sex reversal due to impaired nuclear localization of SRY: A clinical correlation

Li, B., Zhang, W., Chan, G., Jancso-Radek, A., Liu, S. & Weiss, M. A., Dec 7 2001, In : Journal of Biological Chemistry. 276, 49, p. 46480-46484 5 p.

Research output: Contribution to journalArticle

41 Scopus citations

In vivo effects of IL-4, IL-10, and amifostine on cytokine production in patients with acute myelogenous leukemia

Tao, M., Li, B., Nayini, J., Sivaraman, S., Song, S., Larson, A., Toofanfard, M., Chen, H., Venugopal, P. & Preisler, H. D., Jan 1 2001, In : Leukemia and Lymphoma. 41, 1-2, p. 161-168 8 p.

Research output: Contribution to journalArticle

17 Scopus citations

P15INK4B gene methylation and expression in normal, myelodysplastic, and acute myelogenous leukemia cells and in the marrow cells of cured lymphoma patients

Preisler, H. D., Li, B., Chen, H., Fisher, L., Nayini, J., Raza, A., Creech, S. & Venugopal, P., Jan 1 2001, In : Leukemia. 15, 10, p. 1589-1595 7 p.

Research output: Contribution to journalArticle

37 Scopus citations

Poor prognosis acute myelogenous leukemia: 3 - Biological and molecular biological changes during remission induction therapy

Devemy, E., Li, B., Tao, M., Horvath, E., Chopra, H., Fisher, L., Nayini, J., Creech, S., Venugopal, P., Yang, J., Kaspar, C., Hsu, W. T. & Preisler, H. D., Jan 1 2001, In : Leukemia Research. 25, 9, p. 783-791 9 p.

Research output: Contribution to journalArticle

9 Scopus citations

Quantitation of interferon regulatory factor transcripts in patients with acute myeloid leukemia

Perambakam, S., Li, B. & Preisler, H., Jun 21 2001, In : Cancer Investigation. 19, 4, p. 346-351 6 p.

Research output: Contribution to journalArticle

2 Scopus citations

SRY and architectural gene regulation: The kinetic stability of a bent protein-DNA complex can regulate its transcriptional potency

Ukiyama, E., Jancso-Radek, A., Li, B., Milos, L., Zhang, W., Phillips, N. B., Morikawa, N., King, C. Y., Chan, G., Haqq, C. M., Radek, J. T., Poulat, F., Donahoe, P. K. & Weiss, M. A., 2001, In : Molecular Endocrinology. 15, 3, p. 363-377 15 p.

Research output: Contribution to journalArticle

28 Scopus citations
2000

Identification of mRNAs expressed in tumor-infiltrating lymphocytes by a strategy for rapid and high throughput screening

Li, B., Chang, T., Larson, A. & Ding, J., Sep 19 2000, In : Gene. 255, 2, p. 273-279 7 p.

Research output: Contribution to journalArticle

7 Scopus citations

Immunologic character of tumor infiltrating lymphocytes in ovarian carcinoma

Wang, J. H., Tong, S. Q., Li, B., Ding, J. Q., Hu, B. Y., Zhu, Y. M., Lu, D. Y., Hua, Z. D. & Lu, J., Jan 1 2000, In : Chinese Journal of Cancer Research. 12, 2, p. 99-104 6 p.

Research output: Contribution to journalArticle

Poor prognosis acute myelogenous leukemia 2 - Biological and molecular biological characteristics and treatment outcome

Li, B., Yang, J., Tao, M., Nayini, J., Horvath, E., Chopra, H., Meyer, P., Venugopal, P. & Preisler, H. D., Sep 1 2000, In : Leukemia Research. 24, 9, p. 777-789 13 p.

Research output: Contribution to journalArticle

3 Scopus citations

Regulation of serum cytokines following IL-4 and IL-10 therapy in patients with acute myelogenous leukemia

Tao, M., Li, B., Nayini, J., Sivaraman, S., Song, S., Larson, A., Toofanfard, M., Chen, H., Venugopal, P. & Preisler, H. D., Dec 1 2000, In : Blood. 96, 11 PART II

Research output: Contribution to journalArticle

SCF, IL-1β, IL-1ra and GM-CSF in the bone marrow and serum of normal individuals and of AML and CML in patients

Tao, M., Li, B., Nayini, J., Andrews, C. B., Huang, R. W., Devemy, E., Song, S., Venugopal, P. & Preisler, H. D., Jun 2000, In : Cytokine. 12, 6, p. 699-707 9 p.

Research output: Contribution to journalArticle

23 Scopus citations

Signal antonymy unique to myelodysplastic marrows correlates with altered expression of E2F1

Mundle, S. D., Mativi, B. Y., Cartlidge, J. D., Dangerfield, B., Broady-Robinson, L. T., Li, B., Shetty, V., Venugopal, P., Gregory, S. A., Preisler, H. D. & Raza, A., Jun 24 2000, In : British Journal of Haematology. 109, 2, p. 376-381 6 p.

Research output: Contribution to journalArticle

12 Scopus citations

Suppression of telomerase activity and cytokine messenger RNA levels in acute myelogenous leukemia cells in vivo in patients by amifostine and interleukin 4

Preisler, H. D., Li, B., Yang, J., Huang, R. W., Devemy, E., Venugopal, P., Tao, M., Chopra, H., Gregory, S. A., Adler, S., Sivaraman, S., Toofanfard, P., Jajeh, A., Galvez, A. & Robin, E., Mar 1 2000, In : Clinical Cancer Research. 6, 3, p. 807-812 6 p.

Research output: Contribution to journalArticle

14 Scopus citations

Telomerase activity in preleukemia and acute myelogenous leukemia

Li, B., Yang, J., Andrews, C., Chen, Y. X., Toofanfard, P., Huang, R. W., Horvath, E., Chopra, H., Raza, A. & Preisler, H. D., Jan 1 2000, In : Leukemia and Lymphoma. 36, 5-6, p. 579-587 9 p.

Research output: Contribution to journalArticle

23 Scopus citations
1999

Marrow cytokine transcripts and the secondary hematologic disorders

Preisler, H. D., Gao, X. Z., Ming, T., Li, B., Bi, S., Devemy, E., Loew, J. & Raza, A., Jan 1 1999, In : Leukemia and Lymphoma. 35, 3-4, p. 297-302 6 p.

Research output: Contribution to journalArticle

1 Scopus citations

Tumor tissue recycling - A new combination treatment for solid tumors: Experimental and preliminarily clinical research

Li, B., Ding, J., Larson, A. & Song, S., Sep 1 1999, In : In Vivo. 13, 5, p. 433-438 6 p.

Research output: Contribution to journalArticle

4 Scopus citations
1998

Cytokine gene activity in AML cells in vivo in patients

Gao, X. Z., Bi, S., Copra, H., Devemy, E., Venugopal, P., Li, B., Hsu, W. T., Loew, J., Galvez, A., Gregory, S., Yang, J., Horvath, E. & Preisler, H. D., May 1 1998, In : Leukemia Research. 22, 5, p. 429-438 10 p.

Research output: Contribution to journalArticle

17 Scopus citations
1994

A new experimental and clinical approach of combining usage of highly active tumor-infiltrating lymphocytes and highly sensitive antitumor drugs for the advanced malignant tumor

Li, B., Tong, S., Zhang, X., Lu, J., Gu, Q. & Lu, D., Dec 1 1994, In : Chinese Medical Journal. 107, 11, p. 803-807 5 p.

Research output: Contribution to journalArticle

2 Scopus citations

Study on the influence of enzymatic digestion upon tumor-infiltrating lymphocytes

Li, B., Tong, S. Q., Hu, B. Y., Zhu, Y. M., Zhang, X. H., Wu, J. H., Lu, J. & Lu, D. Y., Mar 1 1994, In : Shi yan sheng wu xue bao = Journal of experimental biology. 27, 1, p. 103-107 5 p.

Research output: Contribution to journalArticle

2 Scopus citations