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Research Output

1983

Acute cholecystitis. Hepatobiliary study (99mTc disofenin).

González, Y., Isales, C. M. & Rivera, J. V., Aug 1 1983, In : Boletin de la Asociacion Medica de Puerto Rico. 75, 8, p. 353-354 2 p.

Research output: Contribution to journalArticle

1986

Short term memory in the calcium messenger system. Evidence for a sustained activation of protein kinase C in adrenal glomerulosa cells

Barrett, P. Q., Kojima, I., Kojima, K., Zawalich, K., Isales, C. M. & Rasmussen, H., Jan 1 1986, In : Biochemical Journal. 238, 3, p. 905-912 8 p.

Research output: Contribution to journalArticle

30 Scopus citations

Temporal patterns of protein phosphorylation after angiotensin II, A23187 and/or 12-O-tetradecanoylphorbol 13-acetate in adrenal glomerulosa cells

Barrett, P. Q., Kojima, I., Kojima, K., Zawalich, K., Isales, C. M. & Rasmussen, H., Jan 1 1986, In : Biochemical Journal. 238, 3, p. 893-903 11 p.

Research output: Contribution to journalArticle

31 Scopus citations
1987

Hypercalcemia in breast cancer. Reassessment of the mechanism

Isales, C., Carcangiu, M. L. & Stewart, A. F., Jun 1987, In : The American Journal of Medicine. 82, 6, p. 1143-1147 5 p.

Research output: Contribution to journalArticle

54 Scopus citations
1988
13 Scopus citations

Effect of short-term somatostatin and long-term triiodothyronine administration in a child with nontumours inappropriate thyrotropin secretion

Isales, C. M., Tamborlane, W., Gertner, J. M., Genel, M. & Insogna, K. L., Jan 1 1988, In : The Journal of Pediatrics. 112, 1, p. 51-55 5 p.

Research output: Contribution to journalArticle

4 Scopus citations

The role of cyclic nucleotides in atrial natriuretic peptide-mediated inhibition of aldosterone secretion

Barrett, P. Q. & Isales, C. M., Mar 1 1988, In : Endocrinology. 122, 3, p. 799-808 10 p.

Research output: Contribution to journalArticle

44 Scopus citations
1989

Cycling of Ca2+ across the Plasma Membrane as a Mechanism for Generating a Ca2+ Signal for Cell Activation

RASMUSSEN, HOWARD., BARRETT, PAULA., ZAWALICH, WALTER., ISALES, CARLOS., STEIN, PETER., SMALLWOOD, JOAN., MCCARTHY, RICHARD. & BOLLAG, WENDY., Dec 1989, In : Annals of the New York Academy of Sciences. 568, 1, p. 73-80 8 p.

Research output: Contribution to journalArticle

13 Scopus citations

Effect of ANP on sustained aldosterone secretion stimulated by angiotensin II

Isales, C. M., Bollag, W. B., Kiernan, L. C. & Barrett, P. Q., Jan 1 1989, In : American Journal of Physiology - Cell Physiology. 256, 1, p. 25/1

Research output: Contribution to journalArticle

23 Scopus citations

Role of calcium in angiotensin II-mediated aldosterone secretion

Barrett, P. Q., Isales, C. M., Rasmussen, H., Bollag, W. B., Rasmussen, H., McCarthy, R. T., Rasmussen, H. & McCarthy, R. T., Nov 1989, In : Endocrine Reviews. 10, 4, p. 496-518 23 p.

Research output: Contribution to journalArticle

153 Scopus citations
1990

A potential role for phospholipase-D in the angiotensin II-induced stimulation of aldosterone secretion from bovine adrenal glomerulosa cells

Bollag, W. B., Barrett, P. Q., Isales, C. M., Liscovitch, M. & Rasmussen, H., Jan 1 1990, In : Endocrinology. 127, 3, p. 1436-1443 8 p.

Research output: Contribution to journalArticle

42 Scopus citations

Atrial natriuretic peptide differentially modulates T- and L-type calcium channels

McCarthy, R. T., Isales, C. M., Bollag, W. B., Rasmussen, H. & Barrett, P. Q., 1990, In : American Journal of Physiology - Renal Fluid and Electrolyte Physiology. 258, 3 27-3, p. F473-F478

Research output: Contribution to journalArticle

34 Scopus citations

Calcium ion as intracellular messenger and cellular toxin

Rasmussen, H., Barrett, P., Smallwood, J., Bollag, W. & Isales, C., Jan 1 1990, In : Environmental Health Perspectives. 84, p. 17-25 9 p.

Research output: Contribution to journalArticle

60 Scopus citations
1991

Angiotensin-ii-induced changes in diacylglycerol levels and their potential role in modulating the steroidogenic response

Bollag, W. B., Barrett, P. Q., Isales, C. M. & Rasmussen, H., Jan 1991, In : Endocrinology. 128, 1, p. 231-241 11 p.

Research output: Contribution to journalArticle

44 Scopus citations

Ca2+ channels and aldosterone secretion: Modulation by K+ and atrial natriuretic peptide

Barrett, P. Q., Isales, C. M., Bollag, W. B. & McCarthy, R. T., 1991, In : American Journal of Physiology - Renal Fluid and Electrolyte Physiology. 261, 4 30-4, p. F706-F719

Research output: Contribution to journalArticle

52 Scopus citations

Modulation of Ca2+ channels by atrial natriuretic peptide in the bovine adrenal glomerulosa cell

Barrett, P. Q., Isales, C. M., Bollag, W. B. & McCarthy, R. T., Jan 1 1991, In : Canadian Journal of Physiology and Pharmacology. 69, 10, p. 1553-1560 8 p.

Research output: Contribution to journalArticle

19 Scopus citations

Parathyroid hormone modulates angiotensin II-induced aldosterone secretion from the adrenal glomerulosa cell

Isales, C. M., Barrett, P. Q., Brines, M., Bollag, W. & Rasmussen, H., Jul 1991, In : Endocrinology. 129, 1, p. 489-495 7 p.

Research output: Contribution to journalArticle

52 Scopus citations
1992

ANP-(7-23) stimulates a DHP-sensitive Ca2+ conductance and reduces cellular cAMP via a cGMP-independent mechanism

Isales, C. M., Lewicki, J. A., Nee, J. J. & Barrett, P. Q., Jan 1 1992, In : American Journal of Physiology - Cell Physiology. 263, 2 32-2, p. C334-C342

Research output: Contribution to journalArticle

28 Scopus citations

Ca(2+)-cyclic AMP interactions in sustained cellular responses.

Rasmussen, H., Isales, C. M., Ganesan, S., Calle, R. & Zawalich, W., Jan 1 1992, In : Ciba Foundation symposium. 164

Research output: Contribution to journalReview article

14 Scopus citations

Effects of Ca2+ agonists on cytosolic Ca2+ in isolated hepatocytes and on bile secretion in the isolated perfused rat liver

Nathanson, M. H., Gautam, A., Bruck, R., Isales, C. M. & Boyer, J. L., Jan 1992, In : Hepatology. 15, 1, p. 107-116 10 p.

Research output: Contribution to journalArticle

63 Scopus citations

Immunocytochemical expression and localization of protein kinase C in bovine aortic endothelial cells

Rosales, O. R., Isales, C., Nathanson, M. & Sumpio, B. E., Nov 30 1992, In : Biochemical and Biophysical Research Communications. 189, 1, p. 40-46 7 p.

Research output: Contribution to journalArticle

19 Scopus citations

Parathyroid hormone‐related protein stimulates prostaglandin E2 release from human osteoblast‐like cells: Modulating effect of peptide length

Mitnick, M., Isales, C., Paliwal, I. & Insogna, K., Aug 1992, In : Journal of Bone and Mineral Research. 7, 8, p. 887-896 10 p.

Research output: Contribution to journalArticle

15 Scopus citations

Signal transduction mechanisms involved in carbachol-induced aldosterone secretion from bovine adrenal glomerulosa cells

Bollag, W. B., Barrett, P. Q., Isales, C. M., Liscovitch, M. & Rasmussen, H., Jul 1992, In : Molecular and Cellular Endocrinology. 86, 1-2, p. 93-101 9 p.

Research output: Contribution to journalArticle

13 Scopus citations
1993

Endothelin-1 induces cholestasis which is mediated by an increase in portal pressure

Isales, C. M., Nathanson, M. H. & Bruck, R., Mar 31 1993, In : Biochemical and Biophysical Research Communications. 191, 3, p. 1244-1251 8 p.

Research output: Contribution to journalArticle

22 Scopus citations

Phospholipase C: A Putative Mechanotransducer for Endothelial Cell Response to Acute Hemodynamic Changes

Brophy, C. M., Mills, I., Rosales, O., Isales, C. M. & Sumpio, B. E., Jan 1 1993, In : Biochemical and Biophysical Research Communications. 190, 2, p. 576-581 6 p.

Research output: Contribution to journalArticle

43 Scopus citations

Platelet cytosolic calcium, peripheral hemodynamics, and vasodilatory peptides in liver cirrhosis

Rodríguez-pérez, F., Isales, C. M. & Groszmann, R. J., Jan 1 1993, In : Gastroenterology. 105, 3, p. 863-867 5 p.

Research output: Contribution to journalArticle

21 Scopus citations

Tauroursodeoxycholic acid stimulates hepatocellular exocytosis and mobilizes extracellular Ca++ mechanisms defective in cholestasis

Beuers, U., Nathanson, M. H., Isales, C. M. & Boyer, J. L., Jan 1 1993, In : Journal of Clinical Investigation. 92, 6, p. 2984-2993 10 p.

Research output: Contribution to journalArticle

137 Scopus citations

T-type calcium channels in adrenal glomerulosa cells: GTP-dependent modulation by angiotensin II

McCarthy, R. T., Isales, C. & Rasmussen, H., Jan 1 1993, In : Proceedings of the National Academy of Sciences of the United States of America. 90, 8, p. 3260-3264 5 p.

Research output: Contribution to journalArticle

46 Scopus citations
1994

Atrial natriuretic peptide enhances activity of potassium conductance in adrenal glomerulosa cells

Ganz, M. B., Nee, J. J., Isales, C. M. & Barrett, P. Q., May 13 1994, In : AM.J.PHYSIOL.. 266, 5 part 1, p. 1357-1365 9 p.

Research output: Contribution to journalArticle

19 Scopus citations

Mechanism of insulin-stimulated electrogenic sodium transport

Rodriguez-Commes, J., Isales, C., Kalghati, L., Gasalla-Herraiz, J. & Hayslett, J. P., Sep 1994, In : Kidney International. 46, 3, p. 666-674 9 p.

Research output: Contribution to journalArticle

27 Scopus citations
1995

Adenosine stimulation of Na+ transport is mediated by an A1 receptor and a [Ca2+]i-dependent mechanism

Hayslett, J. P., Macala, L. J., Smallwood, J. I., Kalghatgi, L., Gasalla-Herraiz, J. & Isales, C., Jun 1995, In : Kidney International. 47, 6, p. 1576-1584 9 p.

Research output: Contribution to journalArticle

31 Scopus citations

Calcium Sensitive Probes for the Measurement of Intracellular Calcium: Effects of Buffer System and Magnesium Concentration

Gasalla-Herraiz, J., Rhee, S. & Isales, C. M., Jan 1 1995, In : Biochemical and Biophysical Research Communications. 214, 2, p. 373-388 16 p.

Research output: Contribution to journalArticle

15 Scopus citations

Diacylglycerol production, ca2+ influx, and proteinkinase c activation in sustained cellular responses

Rasmussen, H., Isales, C. M., Calle, R., Throckmorton, D., Gasalla-Herraiz, J., Anderson, M. & McCARTHY, R., Oct 1995, In : Endocrine Reviews. 16, 5, p. 649-681 33 p.

Research output: Contribution to journalArticle

107 Scopus citations

Kinase activation and smooth muscle contraction in the presence and absence of calcium

Whitney, G., Throckmorton, D., Isales, C., Takuwa, Y., Yeh, J., Rasmussen, H. & Brophy, C., Jul 1995, In : Journal of Vascular Surgery. 22, 1, p. 37-44 8 p.

Research output: Contribution to journalArticle

30 Scopus citations

Parathyroid Hormone Stimulates Electrogenic Sodium Transport in A6 Cells

Rodriguezcommes, J., Forrest, J. N., Lopez, R., Gasallaherraiz, J. & Isales, C. M., Jan 1 1995, In : Biochemical and Biophysical Research Communications. 213, 2, p. 688-698 11 p.

Research output: Contribution to journalArticle

4 Scopus citations

Vasopressin-stimulated electrogenic sodium transport in a6 cells is linked to a Ca2+-mobilizing signal mechanism

Hayslett, J. P., Macala, L. J., Smallwood, J. I., Kalghatgi, L., Gassala-Herraiz, J. & Isales, C., Jul 7 1995, In : Journal of Biological Chemistry. 270, 27, p. 16082-16088 7 p.

Research output: Contribution to journalArticle

25 Scopus citations
1996

A midregion parathyroid hormone-related peptide mobilizes cytosolic calcium and stimulates formation of inositol trisphosphate in a squamous carcinoma cell line

Orloff, J. J., Ganz, M. B., Nathanson, M. H., Moyer, M. S., Kats, Y., Mitnick, M., Behal, A., Gasalla-Herraiz, J. & Isales, C. M., Jan 1 1996, In : Endocrinology. 137, 12, p. 5376-5385 10 p.

Research output: Contribution to journalArticle

48 Scopus citations

Tauroursodeoxycholic acid activates protein kinase C in isolated rat hepatocytes

Beuers, U., Throckmorton, D. C., Anderson, M. S., Isales, C. M., Thasler, W., Kullak- Ublick, G. A., Sauter, G., Koebe, H. G., Paumgartner, G. & Boyer, J. L., Jan 1 1996, In : Gastroenterology. 110, 5, p. 1553-1563 11 p.

Research output: Contribution to journalArticle

122 Scopus citations
1997
15 Scopus citations

Exposure of endothelial cells to cyclic strain induces elevations of cytosolic Ca2+ concentration through mobilization of intracellular and extracellular pools

Rosales, O. R., Isales, C. M., Barrett, P. Q., Brophy, C. & Sumpio, B. E., Sep 1 1997, In : Biochemical Journal. 326, 2, p. 385-392 8 p.

Research output: Contribution to journalArticle

42 Scopus citations

Expression of inducible nitric oxide synthase in breast cancer correlates with metastatic disease

Dueñas-Gonzalez, A., Isales, C. M., Del Mar Abad-Hernandez, M., Gonzalez-Sarmiento, R., Sangueza, O. & Rodriguez-Commes, J., Jul 1 1997, In : Modern Pathology. 10, 7, p. 645-649 5 p.

Research output: Contribution to journalArticle

76 Scopus citations

Inhibition of muscarinic-stimulated polyphosphoinositide hydrolysis and Ca2+ mobilization in cat iris sphincter smooth muscle cells by cAMP-elevating agents

Ding, K., Husain, S., Akhtar, R. A., Isales, C. M. & Abdel-Latif, A. A., Sep 1 1997, In : Cellular Signalling. 9, 6, p. 411-421 11 p.

Research output: Contribution to journalArticle

27 Scopus citations

Molecular cloning of a putative tetrodotoxin-resistant sodium channel from dog nodose ganglion neurons

Chen, J., Ikeda, S. R., Lang, W., Isales, C. M. & Wei, X., Nov 20 1997, In : Gene. 202, 1-2, p. 7-14 8 p.

Research output: Contribution to journalArticle

17 Scopus citations

Novel effect of insulin: Insulin-stimulated Na+ transport is mediated by hydrolysis of phosphoinositides

Isales, C., MacAla, L. J., Rodriguez-Commes, J., Gasalla-Herraiz, J. & Hayslett, J. P., Feb 3 1997, In : Biochemical and Biophysical Research Communications. 231, 1, p. 156-159 4 p.

Research output: Contribution to journalArticle

1 Scopus citations

Pancreatic fibrosis with islet cell pseudoneoplastic proliferation as a cause of hypoglycemia [6]

Sangueza, O., Wei, J. & Isales, C. M., Jan 1 1997, In : Annals of internal medicine. 127, 11, p. 1042-1043 2 p.

Research output: Contribution to journalLetter

2 Scopus citations
1998

Fenfluramine potentiates canine pulmonary vasoreactivity to endothelin-1

Barman, S. A. & Isales, C. M., Apr 1998, In : Pulmonary Pharmacology and Therapeutics. 11, 2-3, p. 183-187 5 p.

Research output: Contribution to journalArticle

9 Scopus citations

Overexpression of protein kinase C α and β1 has distinct effects on bovine aortic endothelial cell growth

Rosales, O. R., Isales, C. M. & Bhargava, J., Sep 1 1998, In : Cellular Signalling. 10, 8, p. 589-597 9 p.

Research output: Contribution to journalArticle

11 Scopus citations

pH-dependent fluoride transport in intestinal brush border membrane vesicles

He, H., Ganapathy, V., Isales, C. M. & Whitford, G. M., Jul 17 1998, In : Biochimica et Biophysica Acta - Biomembranes. 1372, 2, p. 244-254 11 p.

Research output: Contribution to journalArticle

19 Scopus citations

Sustained phospholipase D activation in response to angiotensin II but not carbachol in bovine adrenal glomerulosa cells

Jung, E. M., Betancourt-Calle, S., Mann-Blakeney, R. S., Foushee, T., Isales, C. M. & Bollag, W. B., Feb 15 1998, In : Biochemical Journal. 330, 1, p. 445-451 7 p.

Research output: Contribution to journalArticle

22 Scopus citations

Vasopressin-induced activation of protein kinase C in renal epithelial cells

Ali, N., Kantachuvesiri, S., Smallwood, J. I., Macala, L. J., Isales, C., Ji, J., Reilly, R. & Hayslett, J. P., Mar 27 1998, In : Biochimica et Biophysica Acta - Molecular Cell Research. 1402, 2, p. 188-196 9 p.

Research output: Contribution to journalArticle

7 Scopus citations