If you made any changes in Pure, your changes will be visible here soon.

Research Output 1983 2019

1983

Acute cholecystitis. Hepatobiliary study (99mTc disofenin).

González, Y., Isales, C. M. & Rivera, J. V., Aug 1 1983, In : Boletin de la Asociacion Medica de Puerto Rico. 75, 8, p. 353-354 2 p.

Research output: Contribution to journalArticle

Technetium Tc 99m Disofenin
Imino Acids
Acute Cholecystitis
Cholecystitis
Technetium
1986
30 Citations (Scopus)

Short term memory in the calcium messenger system. Evidence for a sustained activation of protein kinase C in adrenal glomerulosa cells

Barrett, P. Q., Kojima, I., Kojima, K., Zawalich, K., Isales, C. M. & Rasmussen, H., Jan 1 1986, In : Biochemical Journal. 238, 3, p. 905-912 8 p.

Research output: Contribution to journalArticle

Zona Glomerulosa
Short-Term Memory
Angiotensin II
Protein Kinase C
Chemical activation
31 Citations (Scopus)

Temporal patterns of protein phosphorylation after angiotensin II, A23187 and/or 12-O-tetradecanoylphorbol 13-acetate in adrenal glomerulosa cells

Barrett, P. Q., Kojima, I., Kojima, K., Zawalich, K., Isales, C. M. & Rasmussen, H., Jan 1 1986, In : Biochemical Journal. 238, 3, p. 893-903 11 p.

Research output: Contribution to journalArticle

Zona Glomerulosa
Phosphorylation
Calcimycin
Tetradecanoylphorbol Acetate
Angiotensin II
1987
53 Citations (Scopus)

Hypercalcemia in breast cancer. Reassessment of the mechanism

Isales, C., Carcangiu, M. L. & Stewart, A. F., Jun 1987, In : The American Journal of Medicine. 82, 6, p. 1143-1147 5 p.

Research output: Contribution to journalArticle

Hypercalcemia
Breast Neoplasms
Bone and Bones
Parathyroid Hormone
Vitamin D
1988
13 Citations (Scopus)
Angiotensins
Atrial Natriuretic Factor
Aldosterone
Calcium
Phosphatidylinositols
4 Citations (Scopus)

Effect of short-term somatostatin and long-term triiodothyronine administration in a child with nontumours inappropriate thyrotropin secretion

Isales, C. M., Tamborlane, W., Gertner, J. M., Genel, M. & Insogna, K. L., Jan 1 1988, In : The Journal of Pediatrics. 112, 1, p. 51-55 5 p.

Research output: Contribution to journalArticle

Drug Administration Schedule
Thyroid Function Tests
Thyrotropin-Releasing Hormone
Triiodothyronine
Preschool Children
44 Citations (Scopus)

The role of cyclic nucleotides in atrial natriuretic peptide-mediated inhibition of aldosterone secretion

Barrett, P. Q. & Isales, C. M., Mar 1 1988, In : Endocrinology. 122, 3, p. 799-808 10 p.

Research output: Contribution to journalArticle

Cyclic Nucleotides
Atrial Natriuretic Factor
Aldosterone
Adrenocorticotropic Hormone
Colforsin
1989
13 Citations (Scopus)

Cycling of Ca2+ across the Plasma Membrane as a Mechanism for Generating a Ca2+ Signal for Cell Activation

RASMUSSEN, HOWARD., BARRETT, PAULA., ZAWALICH, WALTER., Isales, C. M., STEIN, PETER., SMALLWOOD, JOAN., MCCARTHY, RICHARD. & Bollag, W. B., Jan 1 1989, In : Annals of the New York Academy of Sciences. 568, 1, p. 73-80 8 p.

Research output: Contribution to journalArticle

Signal transduction
Cell membranes
Cyclic AMP
Protein Kinase C
Signal Transduction
23 Citations (Scopus)

Effect of ANP on sustained aldosterone secretion stimulated by angiotensin II

Isales, C. M., Bollag, W. B., Kiernan, L. C. & Barrett, P. Q., Jan 1 1989, In : American Journal of Physiology - Cell Physiology. 256, 1

Research output: Contribution to journalArticle

Atrial Natriuretic Factor
Aldosterone
Angiotensin II
Phosphorylation
Diglycerides
151 Citations (Scopus)

Role of calcium in angiotensin II-mediated aldosterone secretion

Barrett, P. Q., Isales, C. M., Rasmussen, H., Bollag, W. B., Rasmussen, H., McCarthy, R. T., Rasmussen, H. & McCarthy, R. T., Jan 1 1989, In : Endocrine Reviews. 10, 4, p. 496-518 23 p.

Research output: Contribution to journalArticle

Aldosterone
Angiotensin II
Atrial Natriuretic Factor
Second Messenger Systems
Calcium
1990
42 Citations (Scopus)

A potential role for phospholipase-D in the angiotensin II-induced stimulation of aldosterone secretion from bovine adrenal glomerulosa cells

Bollag, W. B., Barrett, P. Q., Isales, C. M., Liscovitch, M. & Rasmussen, H., Jan 1 1990, In : Endocrinology. 127, 3, p. 1436-1443 8 p.

Research output: Contribution to journalArticle

Zona Glomerulosa
Phospholipase D
Aldosterone
Angiotensin II
Diglycerides
34 Citations (Scopus)

Atrial natriuretic peptide differentially modulates T- and L-type calcium channels

McCarthy, R. T., Isales, C. M., Bollag, W. B., Rasmussen, H. & Barrett, P. Q., Apr 11 1990, In : American Journal of Physiology - Renal Fluid and Electrolyte Physiology. 258, 3 27-3

Research output: Contribution to journalArticle

T-Type Calcium Channels
L-Type Calcium Channels
Atrial Natriuretic Factor
Calcium Channels
Aldosterone
59 Citations (Scopus)

Calcium ion as intracellular messenger and cellular toxin

Rasmussen, H., Barrett, P., Smallwood, J., Bollag, W. B. & Isales, C. M., Jan 1 1990, In : Environmental Health Perspectives. 84, p. 17-25 9 p.

Research output: Contribution to journalArticle

Protein Kinase C
Diglycerides
Cell Membrane
Ions
Calcium
1991
43 Citations (Scopus)

Angiotensin-ii-induced changes in diacylglycerol levels and their potential role in modulating the steroidogenic response

Bollag, W. B., Barrett, P. Q., Isales, C. M. & Rasmussen, H., Jan 1 1991, In : Endocrinology. 128, 1, p. 231-241 11 p.

Research output: Contribution to journalArticle

Diglycerides
Angiotensins
Angiotensin II
Zona Glomerulosa
Myristic Acid
52 Citations (Scopus)

Ca2+ channels and aldosterone secretion: Modulation by K+ and atrial natriuretic peptide

Barrett, P. Q., Isales, C. M., Bollag, W. B. & McCarthy, R. T., Nov 18 1991, In : American Journal of Physiology - Renal Fluid and Electrolyte Physiology. 261, 4 30-4, p. F706-F719

Research output: Contribution to journalArticle

Atrial Natriuretic Factor
Aldosterone
Mineralocorticoid Receptor Antagonists
Zona Glomerulosa
Nitrendipine
19 Citations (Scopus)

Modulation of Ca2+ channels by atrial natriuretic peptide in the bovine adrenal glomerulosa cell

Barrett, P. Q., Isales, C. M., Bollag, W. B. & McCarthy, R. T., Jan 1 1991, In : Canadian Journal of Physiology and Pharmacology. 69, 10, p. 1553-1560 8 p.

Research output: Contribution to journalArticle

Zona Glomerulosa
Atrial Natriuretic Factor
Calcium Channels
Luminescence
Aldosterone
48 Citations (Scopus)

Parathyroid hormone modulates angiotensin II-induced aldosterone secretion from the adrenal glomerulosa cell

Isales, C. M., Barrett, P. Q., Brines, M., Bollag, W. B. & Rasmussen, H., Jan 1 1991, In : Endocrinology. 129, 1, p. 489-495 7 p.

Research output: Contribution to journalArticle

Zona Glomerulosa
Aldosterone
Parathyroid Hormone
Angiotensin II
Secretory Rate
1992
28 Citations (Scopus)

ANP-(7-23) stimulates a DHP-sensitive Ca2+ conductance and reduces cellular cAMP via a cGMP-independent mechanism

Isales, C. M., Lewicki, J. A., Nee, J. J. & Barrett, P. Q., Sep 3 1992, In : American Journal of Physiology - Cell Physiology. 263, 2 32-2

Research output: Contribution to journalArticle

Cyclic GMP
Atrial Natriuretic Factor
Zona Glomerulosa
Aldosterone
Atrial Natriuretic Factor Receptors
14 Citations (Scopus)

Ca(2+)-cyclic AMP interactions in sustained cellular responses.

Rasmussen, H., Isales, C. M., Ganesan, S., Calle, R. & Zawalich, W., Jan 1 1992, In : Ciba Foundation symposium. 164

Research output: Contribution to journalReview article

Muscle Contraction
Aldosterone
Cyclic AMP
Smooth Muscle
Insulin
62 Citations (Scopus)

Effects of Ca2+ agonists on cytosolic Ca2+ in isolated hepatocytes and on bile secretion in the isolated perfused rat liver

Nathanson, M. H., Gautam, A., Bruck, R., Isales, C. M. & Boyer, J. L., Jan 1 1992, In : Hepatology. 15, 1, p. 107-116 10 p.

Research output: Contribution to journalArticle

Bile
Hepatocytes
Liver
Pressure
Perfusion
19 Citations (Scopus)

Immunocytochemical expression and localization of protein kinase C in bovine aortic endothelial cells

Rosales, O. R., Isales, C., Nathanson, M. & Sumpio, B. E., Nov 30 1992, In : Biochemical and Biophysical Research Communications. 189, 1, p. 40-46 7 p.

Research output: Contribution to journalArticle

Endothelial cells
Phorbol Esters
Protein Kinase C
Endothelial Cells
Confocal microscopy
15 Citations (Scopus)

Parathyroid hormone‐related protein stimulates prostaglandin E2 release from human osteoblast‐like cells: Modulating effect of peptide length

Mitnick, M., Isales, C. M., Paliwal, I. & Insogna, K., Jan 1 1992, In : Journal of Bone and Mineral Research. 7, 8, p. 887-896 10 p.

Research output: Contribution to journalArticle

Dinoprostone
Peptides
Proteins
Amides
Cyclic AMP
13 Citations (Scopus)

Signal transduction mechanisms involved in carbachol-induced aldosterone secretion from bovine adrenal glomerulosa cells

Bollag, W. B., Barrett, P. Q., Isales, C. M., Liscovitch, M. & Rasmussen, H., Jul 1992, In : Molecular and Cellular Endocrinology. 86, 1-2, p. 93-101 9 p.

Research output: Contribution to journalArticle

Zona Glomerulosa
Signal transduction
Diglycerides
Carbachol
Aldosterone
1993
22 Citations (Scopus)

Endothelin-1 induces cholestasis which is mediated by an increase in portal pressure

Isales, C. M., Nathanson, M. H. & Bruck, R., Mar 31 1993, In : Biochemical and Biophysical Research Communications. 191, 3, p. 1244-1251 8 p.

Research output: Contribution to journalArticle

Portal Pressure
Cholestasis
Endothelin-1
Perfusion
Pressure
43 Citations (Scopus)

Phospholipase C: A Putative Mechanotransducer for Endothelial Cell Response to Acute Hemodynamic Changes

Brophy, C. M., Mills, I., Rosales, O., Isales, C. M. & Sumpio, B. E., Jan 1 1993, In : Biochemical and Biophysical Research Communications. 190, 2, p. 576-581 6 p.

Research output: Contribution to journalArticle

Endothelial cells
Hemodynamics
Type C Phospholipases
Endothelial Cells
Signal transduction
21 Citations (Scopus)

Platelet cytosolic calcium, peripheral hemodynamics, and vasodilatory peptides in liver cirrhosis

Rodríguez-pérez, F., Isales, C. M. & Groszmann, R. J., Jan 1 1993, In : Gastroenterology. 105, 3, p. 863-867 5 p.

Research output: Contribution to journalArticle

Liver Cirrhosis
Blood Platelets
Hemodynamics
Calcium
Peptides
137 Citations (Scopus)

Tauroursodeoxycholic acid stimulates hepatocellular exocytosis and mobilizes extracellular Ca++ mechanisms defective in cholestasis

Beuers, U., Nathanson, M. H., Isales, C. M. & Boyer, J. L., Jan 1 1993, In : Journal of Clinical Investigation. 92, 6, p. 2984-2993 10 p.

Research output: Contribution to journalArticle

Cholestasis
Exocytosis
Hepatocytes
Bile
Liver
46 Citations (Scopus)

T-type calcium channels in adrenal glomerulosa cells: GTP-dependent modulation by angiotensin II

McCarthy, R. T., Isales, C. M. & Rasmussen, H., Jan 1 1993, In : Proceedings of the National Academy of Sciences of the United States of America. 90, 8, p. 3260-3264 5 p.

Research output: Contribution to journalArticle

T-Type Calcium Channels
Zona Glomerulosa
Guanosine Triphosphate
Angiotensin II
Calcium Channels
1994
19 Citations (Scopus)

Atrial natriuretic peptide enhances activity of potassium conductance in adrenal glomerulosa cells

Ganz, M. B., Nee, J. J., Isales, C. M. & Barrett, P. Q., May 13 1994, In : AM.J.PHYSIOL.. 266, 5 part 1, p. 1357-1365 9 p.

Research output: Contribution to journalArticle

Zona Glomerulosa
Atrial Natriuretic Factor
Potassium
Atrial Natriuretic Factor Receptors
Aldosterone
27 Citations (Scopus)

Mechanism of insulin-stimulated electrogenic sodium transport

Rodriguez-Commes, J., Isales, C. M., Kalghati, L., Gasalla-Herraiz, J. & Hayslett, J. P., Jan 1 1994, In : Kidney International. 46, 3, p. 666-674 9 p.

Research output: Contribution to journalArticle

Sodium
Insulin
Aldosterone
Trifluoperazine
Calcium-Calmodulin-Dependent Protein Kinases
1995
31 Citations (Scopus)

Adenosine stimulation of Na+ transport is mediated by an A1 receptor and a [Ca2+]i-dependent mechanism

Hayslett, J. P., Macala, L. J., Smallwood, J. I., Kalghatgi, L., Gasalla-Herraiz, J. & Isales, C. M., Jan 1 1995, In : Kidney International. 47, 6, p. 1576-1584 9 p.

Research output: Contribution to journalArticle

Adenosine
Signal Transduction
Sodium
Trifluoperazine
Ion Transport
15 Citations (Scopus)

Calcium Sensitive Probes for the Measurement of Intracellular Calcium: Effects of Buffer System and Magnesium Concentration

Gasalla-Herraiz, J., Rhee, S. & Isales, C. M., Jan 1 1995, In : Biochemical and Biophysical Research Communications. 214, 2, p. 373-388 16 p.

Research output: Contribution to journalArticle

Fura-2
Aequorin
Magnesium
Buffers
Calcium
106 Citations (Scopus)

Diacylglycerol production, ca2+ influx, and proteinkinase c activation in sustained cellular responses

Rasmussen, H., Isales, C. M., Calle, R., Throckmorton, D., Gasalla-Herraiz, J., Anderson, M. & McCARTHY, R., Jan 1 1995, In : Endocrine Reviews. 16, 5, p. 649-681 33 p.

Research output: Contribution to journalArticle

Diglycerides
Protein Kinase C
Transducers
Phosphotransferases
Programmed Instruction
30 Citations (Scopus)

Kinase activation and smooth muscle contraction in the presence and absence of calcium

Whitney, G., Throckmorton, D., Isales, C. M., Takuwa, Y., Yeh, J., Rasmussen, H. & Brophy, C., Jan 1 1995, In : Journal of Vascular Surgery. 22, 1, p. 37-44 8 p.

Research output: Contribution to journalArticle

Phorbol 12,13-Dibutyrate
Muscle Contraction
Vascular Smooth Muscle
Protein Kinase C
Smooth Muscle
4 Citations (Scopus)

Parathyroid Hormone Stimulates Electrogenic Sodium Transport in A6 Cells

Rodriguezcommes, J., Forrest, J. N., Lopez, R., Gasallaherraiz, J. & Isales, C. M., Jan 1 1995, In : Biochemical and Biophysical Research Communications. 213, 2, p. 688-698 11 p.

Research output: Contribution to journalArticle

Parathyroid Hormone
Sodium
Calcium
Nitrendipine
Calcium Channel Blockers
25 Citations (Scopus)

Vasopressin-stimulated electrogenic sodium transport in a6 cells is linked to a Ca2+-mobilizing signal mechanism

Hayslett, J. P., Macala, L. J., Smallwood, J. I., Kalghatgi, L., Gassala-Herraiz, J. & Isales, C. M., Jul 7 1995, In : Journal of Biological Chemistry. 270, 27, p. 16082-16088 7 p.

Research output: Contribution to journalArticle

Arginine Vasopressin
Vasopressins
Sodium
Adenylyl Cyclases
Chemical activation
1996
48 Citations (Scopus)

A midregion parathyroid hormone-related peptide mobilizes cytosolic calcium and stimulates formation of inositol trisphosphate in a squamous carcinoma cell line

Orloff, J. J., Ganz, M. B., Nathanson, M. H., Moyer, M. S., Kats, Y., Mitnick, M., Behal, A., Gasalla-Herraiz, J. & Isales, C. M., Jan 1 1996, In : Endocrinology. 137, 12, p. 5376-5385 10 p.

Research output: Contribution to journalArticle

Parathyroid Hormone-Related Protein
Inositol
Squamous Cell Carcinoma
Calcium
Cell Line
122 Citations (Scopus)

Tauroursodeoxycholic acid activates protein kinase C in isolated rat hepatocytes

Beuers, U., Throckmorton, D. C., Anderson, M. S., Isales, C. M., Thasler, W., Kullak- Ublick, G. A., Sauter, G., Koebe, H. G., Paumgartner, G. & Boyer, J. L., Jan 1 1996, In : Gastroenterology. 110, 5, p. 1553-1563 11 p.

Research output: Contribution to journalArticle

Protein Kinase C
Hepatocytes
Exocytosis
Isoenzymes
Ursodeoxycholic Acid
1997
15 Citations (Scopus)
Protein-Tyrosine Kinases
Canidae
Serotonin
Compliance
Blood Vessels
42 Citations (Scopus)

Exposure of endothelial cells to cyclic strain induces elevations of cytosolic Ca 2+ concentration through mobilization of intracellular and extracellular pools

Rosales, O. R., Isales, C. M., Barrett, P. Q., Brophy, C. & Sumpio, B. E., Sep 1 1997, In : Biochemical Journal. 326, 2, p. 385-392 8 p.

Research output: Contribution to journalArticle

Endothelial cells
Endothelial Cells
Membranes
Aequorin
Charybdotoxin
76 Citations (Scopus)

Expression of inducible nitric oxide synthase in breast cancer correlates with metastatic disease

Dueñas-Gonzalez, A., Isales, C. M., Del Mar Abad-Hernandez, M., Gonzalez-Sarmiento, R., Sangueza, O. & Rodriguez-Commes, J., Jul 1 1997, In : Modern Pathology. 10, 7, p. 645-649 5 p.

Research output: Contribution to journalArticle

Nitric Oxide Synthase Type II
Nitric Oxide Synthase
Breast Neoplasms
Neoplasms
Neoplasm Metastasis
26 Citations (Scopus)

Inhibition of muscarinic-stimulated polyphosphoinositide hydrolysis and Ca2+ mobilization in cat iris sphincter smooth muscle cells by cAMP-elevating agents

Ding, K., Husain, S., Akhtar, R. A., Isales, C. M. & Abdel-Latif, A. A., Sep 1 1997, In : Cellular Signalling. 9, 6, p. 411-421 11 p.

Research output: Contribution to journalArticle

Phosphatidylinositol Phosphates
Carbachol
Iris
Cholinergic Agents
Smooth Muscle Myocytes
17 Citations (Scopus)

Molecular cloning of a putative tetrodotoxin-resistant sodium channel from dog nodose ganglion neurons

Chen, J., Ikeda, S. R., Lang, W., Isales, C. M. & Wei, X., Nov 20 1997, In : Gene. 202, 1-2, p. 7-14 8 p.

Research output: Contribution to journalArticle

Nodose Ganglion
Sodium Channels
Tetrodotoxin
Molecular Cloning
Dogs
1 Citation (Scopus)

Novel effect of insulin: Insulin-stimulated Na+ transport is mediated by hydrolysis of phosphoinositides

Isales, C. M., MacAla, L. J., Rodriguez-Commes, J., Gasalla-Herraiz, J. & Hayslett, J. P., Feb 3 1997, In : Biochemical and Biophysical Research Communications. 231, 1, p. 156-159 4 p.

Research output: Contribution to journalArticle

Phosphatidylinositols
Hydrolysis
Insulin
Inositol
Signal transduction
2 Citations (Scopus)

Pancreatic fibrosis with islet cell pseudoneoplastic proliferation as a cause of hypoglycemia [6]

Sangueza, O., Wei, J. & Isales, C. M., Jan 1 1997, In : Annals of Internal Medicine. 127, 11, p. 1042-1043 2 p.

Research output: Contribution to journalLetter

Islets of Langerhans
Hypoglycemia
Hypertrophy
Pancreas
Fibrosis
1998
8 Citations (Scopus)

Fenfluramine potentiates canine pulmonary vasoreactivity to endothelin-1

Barman, S. A. & Isales, C. M., Jan 1 1998, In : Pulmonary Pharmacology and Therapeutics. 11, 2-3, p. 183-187 5 p.

Research output: Contribution to journalArticle

Fenfluramine
Endothelin-1
Canidae
Lung
Pulmonary Circulation
11 Citations (Scopus)

Overexpression of protein kinase C α and β1 has distinct effects on bovine aortic endothelial cell growth

Rosales, O. R., Isales, C. M. & Bhargava, J., Sep 1 1998, In : Cellular Signalling. 10, 8, p. 589-597 9 p.

Research output: Contribution to journalArticle

Protein Kinase C
Endothelial Cells
Growth
Cell Cycle
Complementary DNA
19 Citations (Scopus)

pH-dependent fluoride transport in intestinal brush border membrane vesicles

He, H., Ganapathy, V., Isales, C. M. & Whitford, G. M., Jul 17 1998, In : Biochimica et Biophysica Acta - Biomembranes. 1372, 2, p. 244-254 11 p.

Research output: Contribution to journalArticle

4-Chloromercuribenzenesulfonate
Brushes
Microvilli
Fluorides
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid
22 Citations (Scopus)

Sustained phospholipase D activation in response to angiotensin II but not carbachol in bovine adrenal glomerulosa cells

Jung, E. M., Betancourt-Calle, S., Mann-Blakeney, R. S., Foushee, T., Isales, C. M. & Bollag, W. B., Feb 15 1998, In : Biochemical Journal. 330, 1, p. 445-451 7 p.

Research output: Contribution to journalArticle

Zona Glomerulosa
Phospholipase D
Carbachol
Angiotensin II
Chemical activation
7 Citations (Scopus)

Vasopressin-induced activation of protein kinase C in renal epithelial cells

Ali, N., Kantachuvesiri, S., Smallwood, J. I., Macala, L. J., Isales, C. M., Ji, J., Reilly, R. & Hayslett, J. P., Mar 27 1998, In : Biochimica et Biophysica Acta - Molecular Cell Research. 1402, 2, p. 188-196 9 p.

Research output: Contribution to journalArticle

Arginine Vasopressin
Vasopressins
Protein Kinase C
Protein Isoforms
Epithelial Cells