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Research Output

1999
60 Scopus citations
2000

Functional parathyroid hormone receptors are present in an umbilical vein endothelial cell line

Isales, C. M., Sumpio, B., Bollag, R. J., Zhong, Q., Ding, K., Du, W., Rodriguez-Commes, J., Lopez, R., Rosales, O. R., Gasalla-Herraiz, J., McCarthy, R. & Barrett, P. Q., Jan 1 2000, In : American Journal of Physiology - Endocrinology and Metabolism. 279, 3 42-3, p. E654-E662

Research output: Contribution to journalArticle

35 Scopus citations

Glucose-dependent insulinotropic peptide signaling pathways in endothelial cells

Zhong, Q., Bollag, R. J., Dransfield, D. T., Gasalla-Herraiz, J., Ding, K. H., Min, L. & Isales, C. M., Nov 8 2000, In : Peptides. 21, 9, p. 1427-1432 6 p.

Research output: Contribution to journalArticle

41 Scopus citations

Osteoblast-derived cells express functional glucose-dependent insulinotropic peptide receptors

Bollag, R. J., Zhong, Q., Phillips, P., Min, L., Zhong, L., Cameron, R., Mulloy, A. L., Rasmussen, H., Qin, F., Ding, K. H. & Isales, C. M., Jan 1 2000, In : Endocrinology. 141, 3, p. 1228-1235 8 p.

Research output: Contribution to journalArticle

177 Scopus citations
2001

Angiotensin II priming of aldosterone secretion with agents that enhance Ca2+ influx

Betancourt-Calle, S., Mann-Blakeney, R. S., Isales, C. M., Calle, R. A. & Bollinger Bollag, W., May 25 2001, In : Molecular and Cellular Endocrinology. 177, 1-2, p. 61-70 10 p.

Research output: Contribution to journalArticle

9 Scopus citations

Differential effects of agonists of aldosterone secretion on steroidogenic acute regulatory phosphorylation

Betancourt-Calle, S., Calle, R. A., Isales, C. M., White, S., Rasmussen, H. & Bollag, W. B., Feb 22 2001, In : Molecular and Cellular Endocrinology. 173, 1-2, p. 87-94 8 p.

Research output: Contribution to journalArticle

35 Scopus citations

Functional analysis of glucose-dependent insulinotropic polypeptide fusion proteins

Ding, K. H., Isales, C. M., Zhong, Q. & Bollag, R. J., Apr 30 2001, In : Peptides. 22, 4, p. 575-582 8 p.

Research output: Contribution to journalArticle

Glucose-dependent insulinotropic peptide is an integrative hormone with osteotropic effects

Bollag, R. J., Zhong, Q., Ding, K. H., Phillips, P., Zhong, L., Qin, F., Cranford, J., Mulloy, A. L., Cameron, R. & Isales, C. M., May 25 2001, In : Molecular and Cellular Endocrinology. 177, 1-2, p. 35-41 7 p.

Research output: Contribution to journalArticle

106 Scopus citations

Microarray analysis of Tbx2-directed gene expression: A possible role in osteogenesis

Chen, J. R., Zhong, Q., Wang, J., Cameron, R. S., Borke, J. L., Isales, C. M. & Bollag, R. J., May 25 2001, In : Molecular and Cellular Endocrinology. 177, 1-2, p. 43-54 12 p.

Research output: Contribution to journalArticle

46 Scopus citations
2002

Parathyroid hormone effects on signaling pathways in endothelial cells vary with peptide concentration

Throckmorton, D., Kurscheid-Reich, D., Rosales, O. R., Rodriguez-Commes, J., Lopez, R., Sumpio, B., Zhong, Q., Ding, K. H., McCarthy, R., Barrett, P. Q. & Isales, C. M., Feb 11 2002, In : Peptides. 23, 1, p. 79-85 7 p.

Research output: Contribution to journalArticle

10 Scopus citations
2003
15 Scopus citations
18 Scopus citations

High glucose augments the angiotensin II-induced activation of JAK2 in vascular smooth muscle cells via the polyol pathway

Shaw, S., Wang, X., Redd, H., Alexander, G. D., Isales, C. M. & Marrero, M. B., Aug 15 2003, In : Journal of Biological Chemistry. 278, 33, p. 30634-30641 8 p.

Research output: Contribution to journalArticle

67 Scopus citations

Negative transcriptional regulation of connexin 43 by Tbx2 in rat immature coronal sutures and ROS 17/2.8 cells in culture

Borke, J. L., Chen, J. R., Yu, J. C., Bollag, R. J., Orellana, M. F. & Isales, C. M., May 1 2003, In : Cleft Palate-Craniofacial Journal. 40, 3, p. 284-290 7 p.

Research output: Contribution to journalArticle

15 Scopus citations

Primary ovarian lymphoma manifesting with severe hypercalcemia

Rizvi, A. A., Bowman, M. A., Vaughters, R. B., Isales, C. & Mulloy, A. L., 2003, In : Endocrine Practice. 9, 5, p. 389-393 5 p.

Research output: Contribution to journalArticle

6 Scopus citations

Tension-Induced Reduction in Connexin 43 Expression in Cranial Sutures is Linked to Transcriptional Regulation by TBX2

Borke, J. L., Yu, J. C., Isales, C. M., Wagle, N., Do, N. N., Chen, J. R. & Bollag, R. J., Nov 1 2003, In : Annals of Plastic Surgery. 51, 5, p. 499-504 6 p.

Research output: Contribution to journalArticle

17 Scopus citations
2004

A patient with concurrent primary hyperaldosteronism and adrenal insufficiency

Puentes, F., Jackson, T. W. & Isales, C. M., Dec 2004, In : American Journal of the Medical Sciences. 328, 6, p. 344-347 4 p.

Research output: Contribution to journalArticle

1 Scopus citations
31 Scopus citations

Leptin deficiency produces contrasting phenotypes in bones of the limb and spine

Hamrick, M. W., Pennington, C., Newton, D., Xie, D. & Isales, C., Mar 1 2004, In : Bone. 34, 3, p. 376-383 8 p.

Research output: Contribution to journalArticle

278 Scopus citations

Tbx2 represses expression of Connexin43 in osteoblastic-like cells

Chen, J. R., Chatterjee, B., Meyer, R., Yu, J. C., Borke, J. L., Isales, C. M., Kirby, M. L., Lo, C. W. & Bollag, R. J., Jun 1 2004, In : Calcified Tissue International. 74, 6, p. 561-573 13 p.

Research output: Contribution to journalArticle

26 Scopus citations

The LTR enhancer of ERV-9 human endogenous retrovirus is active in oocytes and progenitor cells in transgenic zebrafish and humans

Pi, W., Yang, Z., Wang, J., Ruan, L., Yu, X., Ling, J., Krantz, S., Isales, C. M., Conway, S. J., Lin, S. & Tuan Lo, D., Jan 20 2004, In : Proceedings of the National Academy of Sciences of the United States of America. 101, 3, p. 805-810 6 p.

Research output: Contribution to journalArticle

30 Scopus citations
2005
1 Scopus citations

Glucose-dependent insulinotropic polypeptide receptor knockout mice have altered bone turnover

Xie, D., Cheng, H., Hamrick, M., Zhong, Q., Ding, K. H., Correa, D., Williams, S., Mulloy, A., Bollag, W., Bollag, R. J., Runner, R. R., McPherson, J. C., Insogna, K. & Isales, C. M., Dec 1 2005, In : Bone. 37, 6, p. 759-769 11 p.

Research output: Contribution to journalArticle

117 Scopus citations

Multiple melanocortin receptors are expressed in bone cells

Zhong, Q., Sridhar, S., Ruan, L., Ding, K., Xie, D., Insogna, K., Kang, B., Xu, J., Bollag, R. J. & Isales, C. M., May 2005, In : Bone. 36, 5, p. 820-831 12 p.

Research output: Contribution to journalArticle

53 Scopus citations

Muscle-bone interactions in dystrophin-deficient and myostatin-deficient mice

Montgomery, E., Pennington, C., Isales, C. M. & Hamrick, M. W., Sep 1 2005, In : Anatomical Record - Part A Discoveries in Molecular, Cellular, and Evolutionary Biology. 286, 1, p. 814-822 9 p.

Research output: Contribution to journalArticle

38 Scopus citations

SUMO wrestling with type 1 diabetes

Li, M., Guo, D., Isales, C. M., Eizirik, D. L., Atkinson, M., She, J. X. & Wang, C. Y., Jul 1 2005, In : Journal of Molecular Medicine. 83, 7, p. 504-513 10 p.

Research output: Contribution to journalReview article

70 Scopus citations
2006

Age-related loss of muscle mass and bone strength in mice is associated with a decline in physical activity and serum leptin

Hamrick, M. W., Ding, K. H., Pennington, C., Chao, Y. J., Wu, Y. D., Howard, B., Immel, D., Borlongan, C., McNeil, P. L., Bollag, W. B., Curl, W. W., Yu, J. & Isales, C. M., Oct 1 2006, In : Bone. 39, 4, p. 845-853 9 p.

Research output: Contribution to journalArticle

99 Scopus citations

Disordered osteoclast formation in RAGE-deficient mouse establishes an essential role for RAGE in diabetes related bone loss

Ding, K., Wang, Z. Z., Hamrick, M. W., Deng, Z. B., Zhou, L., Kang, B., Yan, S. L., She, J-X., Stern, D. M., Isales, C. M. & Mi, Q. S., Feb 24 2006, In : Biochemical and Biophysical Research Communications. 340, 4, p. 1091-1097 7 p.

Research output: Contribution to journalArticle

87 Scopus citations

Resistance to body fat gain in 'double-muscled' mice fed a high-fat diet

Hamrick, M. W., Pennington, C., Webb, C. N. & Isales, C. M., May 1 2006, In : International Journal of Obesity. 30, 5, p. 868-870 3 p.

Research output: Contribution to journalArticle

38 Scopus citations
2007

Characterization and phospholipase D mediation of the angiotensin II priming response in adrenal glomerulosa cells

Bollag, W. B., Kent, P., White, S., Malinova, M., Isales, C. M. & Calle, R. A., Feb 1 2007, In : Endocrinology. 148, 2, p. 585-593 9 p.

Research output: Contribution to journalArticle

8 Scopus citations

Effects of glucose-dependent insulinotropic peptide on osteoclast function

Zhong, Q., Itokawa, T., Sridhar, S., Ding, K., Xie, D., Kang, B., Bollag, W. B., Bollag, R. J., Hamrick, M. W., Insogna, K. & Isales, C. M., Feb 1 2007, In : American Journal of Physiology - Endocrinology and Metabolism. 292, 2, p. E543-E548

Research output: Contribution to journalArticle

128 Scopus citations
10 Scopus citations

Future developments in therapy

Isales, C. M. & McDonald, J. M., Nov 2007, In : Annals of the New York Academy of Sciences. 1117, p. 258-263 6 p.

Research output: Contribution to journalArticle

1 Scopus citations

Glucose-dependent insulinotropic peptide-overexpressing transgenic mice have increased bone mass

Xie, D., Zhong, Q., Ding, K., Cheng, H., Williams, S., Correa, D., Bollag, W. B., Bollag, R. J., Insogna, K., Troiano, N., Coady, C., Hamrick, M. W. & Isales, C. M., May 1 2007, In : Bone. 40, 5, p. 1352-1360 9 p.

Research output: Contribution to journalArticle

100 Scopus citations

Loss of myostatin (GDF8) function increases osteogenic differentiation of bone marrow-derived mesenchymal stem cells but the osteogenic effect is ablated with unloading

Hamrick, M. W., Shi, X., Zhang, W., Pennington, C., Thakore, H., Haque, M., Kang, B., Isales, C. M., Fulzele, S. & Wenger, K. H., Jun 1 2007, In : Bone. 40, 6, p. 1544-1553 10 p.

Research output: Contribution to journalArticle

108 Scopus citations

Pituitary glycoprotein hormone receptors in non-endocrine organs

Blair, H. C., Wells, A. & Isales, C. M., Aug 1 2007, In : Trends in Endocrinology and Metabolism. 18, 6, p. 227-233 7 p.

Research output: Contribution to journalArticle

11 Scopus citations
1 Scopus citations
2008

Age-related changes in the osteogenic differentiation potential of mouse bone marrow stromal cells

Zhang, W., Ou, G., Hamrick, M. W., Hill, W. D., Borke, J., Wenger, K., Chutkan, N., Yu, J. C., Mi, Q. S., Isales, C. M. & Shi, X. M., Jul 1 2008, In : Journal of Bone and Mineral Research. 23, 7, p. 1118-1128 11 p.

Research output: Contribution to journalArticle

77 Scopus citations
87 Scopus citations

CART deficiency increases body weight but does not alter bone strength

Bartell, S. M., Isales, C. M., Baile, C. A., Kuhar, M. J. & Hamrick, M. W., Jun 1 2008, In : Journal of Musculoskeletal Neuronal Interactions. 8, 2, p. 146-153 8 p.

Research output: Contribution to journalArticle

10 Scopus citations

Impact of glucose-dependent insulinotropic peptide on age-induced bone loss

Ding, K. H., Shi, X. M., Zhong, Q., Kang, B., Xie, D., Bollag, W. B., Bollag, R. J., Hill, W., Washington, W., Mi, Q. S., Insogna, K., Chutkan, N., Hamrick, M. & Isales, C. M., Apr 1 2008, In : Journal of Bone and Mineral Research. 23, 4, p. 536-543 8 p.

Research output: Contribution to journalArticle

55 Scopus citations

Nutritional hormones and the entero-osseous axis

Isales, C. M. & Hamrick, M., Dec 1 2008, In : Journal of Musculoskeletal Neuronal Interactions. 8, 4, p. 348-350 3 p.

Research output: Contribution to journalArticle

2 Scopus citations

Phorbol ester increases mitochondrial cholesterol content in NCI H295R cells

Bollag, W. B., Kent, P., White, S., Wilson, M. V., Isales, C. M. & Calle, R. A., Dec 16 2008, In : Molecular and Cellular Endocrinology. 296, 1-2, p. 53-57 5 p.

Research output: Contribution to journalArticle

8 Scopus citations
24 Scopus citations
2009

Diagnosis of pheochromocytoma in the setting of Parkinson disease

Mehta, S. H., Prakash, R., Prisant, L. M., Isales, C. M., Morgan, J. C., Williams, H. & Sethi, K. D., Oct 23 2009, In : Nature Reviews Neurology. 5, 6, p. 343-347 5 p.

Research output: Contribution to journalArticle

6 Scopus citations

Regulation of Aldosterone Production

Rainey, W. E., Bollag, W. B. & Isales, C. M., Jan 1 2009, Textbook of Nephro-Endocrinology. Elsevier Inc., p. 361-381 21 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Spontaneous bone loss in RIP-iNoS transgenic mouse: A mouse model for diabetes-mediated osteopenia/osteoporosis

Mi, Q. S., Yan, S. L., Wang, Z. Z., Ding, K., Li, C., Wang, L., Zhou, L., Yamamoto, Y., Yamamoto, H., Okamoto, H. & Isales, C. M., Dec 15 2009, In : Cell Cycle. 8, 24, p. 4179-4181 3 p.

Research output: Contribution to journalLetter

1 Scopus citations

The role of calcium influx pathways in phospholipase D activation in bovine adrenal glomerulosa cells

Qin, H., Kent, P., Isales, C. M., Parker, P. M., Wilson, M. V. & Bollag, W. B., Oct 5 2009, In : Journal of Endocrinology. 202, 1, p. 77-86 10 p.

Research output: Contribution to journalArticle

8 Scopus citations
2010

ACTH is a novel regulator of bone mass

Isales, C. M., Zaidi, M. & Blair, H. C., Jan 1 2010, Skeletal Biology and Medicine. Blackwell Publishing Inc., p. 110-116 7 p. (Annals of the New York Academy of Sciences; vol. 1192).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

44 Scopus citations

ACTH protects against glucocorticoid-induced osteonecrosis of bone

Zaidi, M., Sun, L., Robinson, L. J., Tourkova, I. L., Liu, L., Wang, Y., Zhu, L. L., Liu, X., Li, J., Peng, Y., Yang, G., Shi, X. M., Levine, A., Iqbal, J., Yaroslavskiy, B. B., Isales, C. M. & Blair, H. C., May 11 2010, In : Proceedings of the National Academy of Sciences of the United States of America. 107, 19, p. 8782-8787 6 p.

Research output: Contribution to journalArticle

93 Scopus citations