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Research Output 1983 2019

32 Citations (Scopus)

25-Hydroxyvitamin D, insulin-like growth factor-I, and bone mineral accrual during growth

Breen, M. E., Laing, E. M., Hall, D. B., Hausman, D. B., Taylor, R. G., Isales, C. M., Ding, K., Pollock, N. K., Hamrick, M. W., Baile, C. A. & Lewis, R. D., Jan 1 2011, In : Journal of Clinical Endocrinology and Metabolism. 96, 1

Research output: Contribution to journalArticle

Insulin-Like Growth Factor I
Minerals
Bone
Bone Density
Bone and Bones
24 Citations (Scopus)
Leptin Receptors
muscular atrophy
myoblasts
Muscular Atrophy
Myoblasts
57 Citations (Scopus)
Hydroxybutyrates
Ketone Bodies
Diabetic Ketoacidosis
Endothelin-1
Vascular Endothelial Growth Factor A
40 Citations (Scopus)

ACTH is a novel regulator of bone mass

Isales, C. M., Zaidi, M. & Blair, H. C., Jan 1 2010, Skeletal Biology and Medicine. Blackwell Publishing Inc., p. 110-116 7 p. (Annals of the New York Academy of Sciences; vol. 1192).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Adrenocorticotropic Hormone
Bone
Bone and Bones
Osteoblasts
Melanocortin Receptors
82 Citations (Scopus)

ACTH protects against glucocorticoid-induced osteonecrosis of bone

Zaidi, M., Sun, L., Robinson, L. J., Tourkova, I. L., Liu, L., Wang, Y., Zhu, L. L., Liu, X., Li, J., Peng, Y., Yang, G., Shi, X. M., Levine, A., Iqbal, J., Yaroslavskiy, B. B., Isales, C. M. & Blair, H. C., May 11 2010, In : Proceedings of the National Academy of Sciences of the United States of America. 107, 19, p. 8782-8787 6 p.

Research output: Contribution to journalArticle

Osteonecrosis
Adrenocorticotropic Hormone
Glucocorticoids
Bone and Bones
Bone Remodeling

Acute cholecystitis. Hepatobiliary study (99mTc disofenin).

González, Y., Isales, C. M. & Rivera, J. V., Aug 1 1983, In : Boletin de la Asociacion Medica de Puerto Rico. 75, 8, p. 353-354 2 p.

Research output: Contribution to journalArticle

Technetium Tc 99m Disofenin
Imino Acids
Acute Cholecystitis
Cholecystitis
Technetium
31 Citations (Scopus)

Adenosine stimulation of Na+ transport is mediated by an A1 receptor and a [Ca2+]i-dependent mechanism

Hayslett, J. P., Macala, L. J., Smallwood, J. I., Kalghatgi, L., Gasalla-Herraiz, J. & Isales, C. M., Jan 1 1995, In : Kidney International. 47, 6, p. 1576-1584 9 p.

Research output: Contribution to journalArticle

Adenosine
Signal Transduction
Sodium
Trifluoperazine
Ion Transport

Age-dependent oxidative stress elevates arginase 1 and uncoupled nitric oxide synthesis in skeletal muscle of aged mice

Pandya, C. D., Lee, B., Toque, H. A., Mendhe, B., Bragg, R. T., Pandya, B., Atawia, R. T., Isales, C., Hamrick, M., Caldwell, R. W. & Fulzele, S., Jan 1 2019, In : Oxidative medicine and cellular longevity. 2019, 1704650.

Research output: Contribution to journalArticle

Open Access
Arginase
Oxidative stress
Muscle
Nitric Oxide
Skeletal Muscle
72 Citations (Scopus)

Age-related changes in the osteogenic differentiation potential of mouse bone marrow stromal cells

Zhang, W., Ou, G., Hamrick, M. W., Hill, W. D., Borke, J., Wenger, K., Chutkan, N., Yu, J. C., Mi, Q. S., Isales, C. M. & Shi, X. M., Jul 1 2008, In : Journal of Bone and Mineral Research. 23, 7, p. 1118-1128 11 p.

Research output: Contribution to journalArticle

Mesenchymal Stromal Cells
Cell Count
Stem Cells
Inbred C57BL Mouse
Cell Differentiation
91 Citations (Scopus)

Age-related loss of muscle mass and bone strength in mice is associated with a decline in physical activity and serum leptin

Hamrick, M. W., Ding, K. H., Pennington, C., Chao, Y. J., Wu, Y. D., Howard, B., Immel, D., Borlongan, C., McNeil, P. L., Bollag, W. B., Curl, W. W., Yu, J. & Isales, C. M., Oct 1 2006, In : Bone. 39, 4, p. 845-853 9 p.

Research output: Contribution to journalArticle

Leptin
Bone and Bones
Muscles
Serum
Adipose Tissue
48 Citations (Scopus)

A midregion parathyroid hormone-related peptide mobilizes cytosolic calcium and stimulates formation of inositol trisphosphate in a squamous carcinoma cell line

Orloff, J. J., Ganz, M. B., Nathanson, M. H., Moyer, M. S., Kats, Y., Mitnick, M., Behal, A., Gasalla-Herraiz, J. & Isales, C. M., Jan 1 1996, In : Endocrinology. 137, 12, p. 5376-5385 10 p.

Research output: Contribution to journalArticle

Parathyroid Hormone-Related Protein
Inositol
Squamous Cell Carcinoma
Calcium
Cell Line
4 Citations (Scopus)

Amino acids as signaling molecules modulating bone turnover

Ding, K., Cain, M., Davis, M., Bergson, C. M., McGee Lawrence, M. E., Perkins, C., Hardigan, T., Shi, X. M., Zhong, Q., Xu, J., Bollag, W. B., Hill, W. D., Elsalanty, M. E., Hunter, D. M., Isales, M. C., Lopez, P., Hamrick, M. W. & Isales, C. M., Oct 1 2018, In : Bone. 115, p. 15-24 10 p.

Research output: Contribution to journalReview article

Bone Remodeling
Amino Acids
Protein-Restricted Diet
Mesenchymal Stromal Cells
Calcium-Sensing Receptors
35 Citations (Scopus)
Myostatin
Bone Density
Muscle
Bone
Bone and Bones
43 Citations (Scopus)

Angiotensin-ii-induced changes in diacylglycerol levels and their potential role in modulating the steroidogenic response

Bollag, W. B., Barrett, P. Q., Isales, C. M. & Rasmussen, H., Jan 1 1991, In : Endocrinology. 128, 1, p. 231-241 11 p.

Research output: Contribution to journalArticle

Diglycerides
Angiotensins
Angiotensin II
Zona Glomerulosa
Myristic Acid
9 Citations (Scopus)

Angiotensin II priming of aldosterone secretion with agents that enhance Ca2+ influx

Betancourt-Calle, S., Mann-Blakeney, R. S., Isales, C. M., Calle, R. A. & Bollag, W. B., May 25 2001, In : Molecular and Cellular Endocrinology. 177, 1-2, p. 61-70 10 p.

Research output: Contribution to journalArticle

Aldosterone
Angiotensin II
Phosphorylation
Saralasin
Protein Kinase C
55 Citations (Scopus)

A novel Y152C KCNJ5 mutation responsible for familial hyperaldosteronism type III

Monticone, S., Hattangady, N. G., Penton, D., Isales, C. M., Edwards, M. A., Williams, T. A., Sterner, C., Warth, R., Mulatero, P. & Rainey, W. E., Nov 1 2013, In : Journal of Clinical Endocrinology and Metabolism. 98, 11, p. E1861-E1865

Research output: Contribution to journalArticle

Cytochrome P-450 CYP11B2
Inwardly Rectifying Potassium Channel
Gene expression
Mutation
Hyperaldosteronism
28 Citations (Scopus)

ANP-(7-23) stimulates a DHP-sensitive Ca2+ conductance and reduces cellular cAMP via a cGMP-independent mechanism

Isales, C. M., Lewicki, J. A., Nee, J. J. & Barrett, P. Q., Sep 3 1992, In : American Journal of Physiology - Cell Physiology. 263, 2 32-2

Research output: Contribution to journalArticle

Cyclic GMP
Atrial Natriuretic Factor
Zona Glomerulosa
Aldosterone
Atrial Natriuretic Factor Receptors
1 Citation (Scopus)

A patient with concurrent primary hyperaldosteronism and adrenal insufficiency

Puentes, F., Jackson, T. W. & Isales, C. M., Jan 1 2004, In : American Journal of the Medical Sciences. 328, 6, p. 344-347 4 p.

Research output: Contribution to journalArticle

Cosyntropin
Addison Disease
Hyperaldosteronism
Aortic Rupture
Adrenal Insufficiency
42 Citations (Scopus)

A potential role for phospholipase-D in the angiotensin II-induced stimulation of aldosterone secretion from bovine adrenal glomerulosa cells

Bollag, W. B., Barrett, P. Q., Isales, C. M., Liscovitch, M. & Rasmussen, H., Jan 1 1990, In : Endocrinology. 127, 3, p. 1436-1443 8 p.

Research output: Contribution to journalArticle

Zona Glomerulosa
Phospholipase D
Aldosterone
Angiotensin II
Diglycerides
6 Citations (Scopus)

Aromatic amino acid activation of signaling pathways in bone marrow mesenchymal stem cells depends on oxygen tension

Refaey, M. E., Zhong, Q., Hill, W. D., Shi, X. M., Hamrick, M. W., Bailey, L., Johnson, M., Xu, J., Bollag, W. B., Chutkan, N. & Isales, C. M., Apr 11 2014, In : PloS one. 9, 4, e91108.

Research output: Contribution to journalArticle

Aromatic Amino Acids
bone marrow cells
Stem cells
Mesenchymal Stromal Cells
aromatic compounds

Association of blood n-3 fatty acid with bone mass and bone marrow TRAP-5b in the elderly with and without hip fracture

Kim, B. J., Yoo, H. J., Park, S. J., Kwak, M. K., Lee, S. H., Kim, S. J., Hamrick, M. W., Isales, C. M., Ahn, S. H. & Koh, J. M., May 1 2019, In : Osteoporosis International. 30, 5, p. 1071-1078 8 p.

Research output: Contribution to journalArticle

Omega-3 Fatty Acids
Hip Fractures
Bone Marrow
Bone and Bones
Osteoarthritis
1 Citation (Scopus)

Association of Dietary Niacin Intake With Incident Hip Fracture, BMD, and Body Composition: The Cardiovascular Health Study

Carbone, L. D., Bůžková, P., Fink, H. A., Raiford, M., Le, B., Isales, C. M., Shikany, J. M., Coughlin, S. S. & Robbins, J. A., Apr 1 2019, In : Journal of Bone and Mineral Research. 34, 4, p. 643-652 10 p.

Research output: Contribution to journalArticle

Pelvic Bones
Niacin
Hip Fractures
Body Composition
Bone Density
8 Citations (Scopus)

Association of DPP-4 activity with BMD, body composition, and incident hip fracture: the Cardiovascular Health Study

Carbone, L. D., Bůžková, P., Fink, H. A., Robbins, J. A., Bethel, M., Isales, C. M. & Hill, W. D., May 1 2017, In : Osteoporosis International. 28, 5, p. 1631-1640 10 p.

Research output: Contribution to journalArticle

Hip Fractures
Body Composition
Bone Density
Health
Independent Living
2 Citations (Scopus)

Association of serum TSH with handgrip strength in community-dwelling euthyroid elderly

Kim, B. J., Lee, S. H., Isales, C. M., Hamrick, M. W., Kwak, M. K. & Koh, J. M., Jan 1 2018, In : Journal of Clinical Endocrinology and Metabolism. 103, 11, p. 3986-3992 7 p.

Research output: Contribution to journalArticle

Independent Living
Muscle
Muscle Strength
Muscle Strength Dynamometer
Serum
34 Citations (Scopus)

Atrial natriuretic peptide differentially modulates T- and L-type calcium channels

McCarthy, R. T., Isales, C. M., Bollag, W. B., Rasmussen, H. & Barrett, P. Q., Apr 11 1990, In : American Journal of Physiology - Renal Fluid and Electrolyte Physiology. 258, 3 27-3

Research output: Contribution to journalArticle

T-Type Calcium Channels
L-Type Calcium Channels
Atrial Natriuretic Factor
Calcium Channels
Aldosterone
19 Citations (Scopus)

Atrial natriuretic peptide enhances activity of potassium conductance in adrenal glomerulosa cells

Ganz, M. B., Nee, J. J., Isales, C. M. & Barrett, P. Q., May 13 1994, In : AM.J.PHYSIOL.. 266, 5 part 1, p. 1357-1365 9 p.

Research output: Contribution to journalArticle

Zona Glomerulosa
Atrial Natriuretic Factor
Potassium
Atrial Natriuretic Factor Receptors
Aldosterone
13 Citations (Scopus)
Angiotensins
Atrial Natriuretic Factor
Aldosterone
Calcium
Phosphatidylinositols
14 Citations (Scopus)

Ca(2+)-cyclic AMP interactions in sustained cellular responses.

Rasmussen, H., Isales, C. M., Ganesan, S., Calle, R. & Zawalich, W., Jan 1 1992, In : Ciba Foundation symposium. 164

Research output: Contribution to journalReview article

Muscle Contraction
Aldosterone
Cyclic AMP
Smooth Muscle
Insulin
52 Citations (Scopus)

Ca2+ channels and aldosterone secretion: Modulation by K+ and atrial natriuretic peptide

Barrett, P. Q., Isales, C. M., Bollag, W. B. & McCarthy, R. T., Nov 18 1991, In : American Journal of Physiology - Renal Fluid and Electrolyte Physiology. 261, 4 30-4, p. F706-F719

Research output: Contribution to journalArticle

Atrial Natriuretic Factor
Aldosterone
Mineralocorticoid Receptor Antagonists
Zona Glomerulosa
Nitrendipine
15 Citations (Scopus)

Cadmium intake and systemic exposure in postmenopausal women and age-matched men who smoke cigarettes

Ebert-McNeill, A., Clark, S. P., Miller, J. J., Birdsall, P., Chandar, M., Wu, L., Cerny, E. A., Hall, P. H., Johnson, M. H., Isales, C. M., Chutkan, N. & Bhattacharyya, M. H., Nov 1 2012, In : Toxicological Sciences. 130, 1, p. 191-204 14 p., kfs226.

Research output: Contribution to journalArticle

Cadmium
Smoke
Tobacco Products
Blood
Nutrition
59 Citations (Scopus)

Calcium ion as intracellular messenger and cellular toxin

Rasmussen, H., Barrett, P., Smallwood, J., Bollag, W. B. & Isales, C. M., Jan 1 1990, In : Environmental Health Perspectives. 84, p. 17-25 9 p.

Research output: Contribution to journalArticle

Protein Kinase C
Diglycerides
Cell Membrane
Ions
Calcium
15 Citations (Scopus)

Calcium Sensitive Probes for the Measurement of Intracellular Calcium: Effects of Buffer System and Magnesium Concentration

Gasalla-Herraiz, J., Rhee, S. & Isales, C. M., Jan 1 1995, In : Biochemical and Biophysical Research Communications. 214, 2, p. 373-388 16 p.

Research output: Contribution to journalArticle

Fura-2
Aequorin
Magnesium
Buffers
Calcium
5 Citations (Scopus)

Caloric restriction and the adipokine leptin alter the SDF-1 signaling axis in bone marrow and in bone marrow derived mesenchymal stem cells

Periyasamy Thandavan, S., Herberg, S., Arounleut, P., Upadhyay, S., Dukes, A., Davis, C. M., Johnson, M. H., McGee Lawrence, M. E., Hamrick, M. W., Isales, C. M. & Hill, W. D., Jul 5 2015, In : Molecular and Cellular Endocrinology. 410, p. 64-72 9 p.

Research output: Contribution to journalReview article

Chemokine CXCL12
Caloric Restriction
Adipokines
Leptin
Stem cells
85 Citations (Scopus)
Caloric Restriction
Skeleton
Body Weight
Leptin
Bone and Bones
15 Citations (Scopus)
Protein-Tyrosine Kinases
Canidae
Serotonin
Compliance
Blood Vessels
1 Citation (Scopus)

Carboxy-terminal PTH fragments stimulate [3H]thymidine incorporation in vascular endothelial cells

Ding, K., Zhong, Q., Xie, D., Xu, J., Bollag, R. J., Bollag, W. B. & Isales, C. M., Jan 1 2005, In : Peptides. 26, 5, p. 853-862 10 p.

Research output: Contribution to journalArticle

Endothelial cells
Human Umbilical Vein Endothelial Cells
Thymidine
Endothelial Cells
Molecules
10 Citations (Scopus)

CART deficiency increases body weight but does not alter bone strength

Bartell, S. M., Isales, C. M., Baile, C. A., Kuhar, M. J. & Hamrick, M. W., Jun 1 2008, In : Journal of Musculoskeletal Neuronal Interactions. 8, 2, p. 146-153 8 p.

Research output: Contribution to journalArticle

Amphetamine
Cocaine
Body Weight
Bone and Bones
Femur
8 Citations (Scopus)

Characterization and phospholipase D mediation of the angiotensin II priming response in adrenal glomerulosa cells

Bollag, W. B., Kent, P., White, S., Malinova, M., Isales, C. M. & Calle, R. A., Feb 1 2007, In : Endocrinology. 148, 2, p. 585-593 9 p.

Research output: Contribution to journalArticle

Zona Glomerulosa
Phospholipase D
Angiotensin II
Phorbol 12,13-Dibutyrate
Diglycerides
12 Citations (Scopus)

Chemically defined and xeno-free cryopreservation of human adipose-derived stem cells

López, M., Bollag, R. J., Yu, J. C., Isales, C. M. & Eroglu, A., Mar 1 2016, In : PloS one. 11, 3, e0152161.

Research output: Contribution to journalArticle

Cryopreservation
Stem cells
cryopreservation
stem cells
Stem Cells
1 Citation (Scopus)

Comparative analysis of sodium coupled vitamin C transporter 2 in human osteoarthritis grade 1 and grade 3 tissues

Blackburn, A. R., Hamrick, M. W., Chutkan, N., Sangani, R., Waller, J. L., Corpe, R. S., Prasad, P. D., Isales, C. M., Ganapathy, V. & Fulzele, S. T., Jan 8 2014, In : BMC Musculoskeletal Disorders. 15, 1, 9.

Research output: Contribution to journalArticle

Sodium-Coupled Vitamin C Transporters
Articular Cartilage
Osteoarthritis
Real-Time Polymerase Chain Reaction
Hematoxylin
12 Citations (Scopus)
Leucine Zippers
T-cells
Regulatory T-Lymphocytes
Crosstalk
Stem cells
13 Citations (Scopus)

Cycling of Ca2+ across the Plasma Membrane as a Mechanism for Generating a Ca2+ Signal for Cell Activation

RASMUSSEN, HOWARD., BARRETT, PAULA., ZAWALICH, WALTER., Isales, C. M., STEIN, PETER., SMALLWOOD, JOAN., MCCARTHY, RICHARD. & Bollag, W. B., Jan 1 1989, In : Annals of the New York Academy of Sciences. 568, 1, p. 73-80 8 p.

Research output: Contribution to journalArticle

Signal transduction
Cell membranes
Cyclic AMP
Protein Kinase C
Signal Transduction
1 Citation (Scopus)
Osteogenesis
Bone Density
Protein Kinases
Minerals
Bone
8 Citations (Scopus)

Deregulation of arginase induces bone complications in high-fat/high-sucrose diet diabetic mouse model

Bhatta, A., Sangani, R., Kolhe, R. B., Flores Toque, H. A., Cain, M., Wong, A., Howie, N., Shinde, R., Elsalanty, M. E., Yao, L., Chutkan, N., Hunter, M., Caldwell, R. B., Isales, C. M., Caldwell, R. W. & Fulzele, S. T., Feb 15 2016, In : Molecular and Cellular Endocrinology. 422, p. 211-220 10 p.

Research output: Contribution to journalArticle

Arginase
Deregulation
High Fat Diet
Nutrition
Sucrose
106 Citations (Scopus)

Diacylglycerol production, ca2+ influx, and proteinkinase c activation in sustained cellular responses

Rasmussen, H., Isales, C. M., Calle, R., Throckmorton, D., Gasalla-Herraiz, J., Anderson, M. & McCARTHY, R., Jan 1 1995, In : Endocrine Reviews. 16, 5, p. 649-681 33 p.

Research output: Contribution to journalArticle

Diglycerides
Protein Kinase C
Transducers
Phosphotransferases
Programmed Instruction
6 Citations (Scopus)

Diagnosis of pheochromocytoma in the setting of Parkinson disease

Mehta, S. H., Prakash, R., Prisant, L. M., Isales, C. M., Morgan, J. C., Williams, H. T. & Sethi, K. D., Oct 23 2009, In : Nature Reviews Neurology. 5, 6, p. 343-347 5 p.

Research output: Contribution to journalArticle

Pheochromocytoma
Parkinson Disease
Hyperplasia
Pallor
Sweating
35 Citations (Scopus)

Differential effects of agonists of aldosterone secretion on steroidogenic acute regulatory phosphorylation

Betancourt-Calle, S., Calle, R. A., Isales, C. M., White, S., Rasmussen, H. & Bollag, W. B., Feb 22 2001, In : Molecular and Cellular Endocrinology. 173, 1-2, p. 87-94 8 p.

Research output: Contribution to journalArticle

Phosphorylation
Aldosterone
Tetradecanoylphorbol Acetate
Angiotensin II
Adrenocorticotropic Hormone
3 Citations (Scopus)

Differentially expressed genes in PPARγ-deficient MSCs

Su, Y., Shen, X., Chen, J., Isales, C. M., Zhao, J. & Shi, X. M., Aug 15 2018, In : Molecular and Cellular Endocrinology. 471, p. 97-104 8 p.

Research output: Contribution to journalReview article

PPAR gamma
Mesenchymal Stromal Cells
Genes
RNA Sequence Analysis
Biological Phenomena
79 Citations (Scopus)

Disordered osteoclast formation in RAGE-deficient mouse establishes an essential role for RAGE in diabetes related bone loss

Ding, K., Wang, Z. Z., Hamrick, M. W., Deng, Z. B., Zhou, L., Kang, B., Yan, S. L., She, J-X., Stern, D. M., Isales, C. M. & Mi, Q. S., Feb 24 2006, In : Biochemical and Biophysical Research Communications. 340, 4, p. 1091-1097 7 p.

Research output: Contribution to journalArticle

Osteoclasts
Medical problems
Bone
Bone and Bones
Advanced Glycosylation End Product-Specific Receptor
23 Citations (Scopus)

Effect of ANP on sustained aldosterone secretion stimulated by angiotensin II

Isales, C. M., Bollag, W. B., Kiernan, L. C. & Barrett, P. Q., Jan 1 1989, In : American Journal of Physiology - Cell Physiology. 256, 1

Research output: Contribution to journalArticle

Atrial Natriuretic Factor
Aldosterone
Angiotensin II
Phosphorylation
Diglycerides