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Research Output 1983 2019

2005
37 Citations (Scopus)

Muscle-bone interactions in dystrophin-deficient and myostatin-deficient mice

Montgomery, E., Pennington, C., Isales, C. M. & Hamrick, M. W., Sep 1 2005, In : Anatomical Record - Part A Discoveries in Molecular, Cellular, and Evolutionary Biology. 286, 1, p. 814-822 9 p.

Research output: Contribution to journalArticle

Myostatin
dystrophin
myostatin
Dystrophin
bones
68 Citations (Scopus)

SUMO wrestling with type 1 diabetes

Li, M., Guo, D., Isales, C. M., Eizirik, D. L., Atkinson, M., She, J-X. & Wang, C. Y., Jul 1 2005, In : Journal of Molecular Medicine. 83, 7, p. 504-513 10 p.

Research output: Contribution to journalReview article

Wrestling
Sumoylation
Ubiquitin
Type 1 Diabetes Mellitus
Ubiquitins
2004
1 Citation (Scopus)

A patient with concurrent primary hyperaldosteronism and adrenal insufficiency

Puentes, F., Jackson, T. W. & Isales, C. M., Jan 1 2004, In : American Journal of the Medical Sciences. 328, 6, p. 344-347 4 p.

Research output: Contribution to journalArticle

Cosyntropin
Addison Disease
Hyperaldosteronism
Aortic Rupture
Adrenal Insufficiency
27 Citations (Scopus)
Gastric Inhibitory Polypeptide
Hepatic Artery
Endothelial cells
Portal Vein
Endothelial Cells
267 Citations (Scopus)

Leptin deficiency produces contrasting phenotypes in bones of the limb and spine

Hamrick, M. W., Pennington, C., Newton, D., Xie, D. & Isales, C., Mar 1 2004, In : Bone. 34, 3, p. 376-383 8 p.

Research output: Contribution to journalArticle

Leptin
Spine
Extremities
Phenotype
Bone and Bones
25 Citations (Scopus)

Tbx2 represses expression of Connexin43 in osteoblastic-like cells

Chen, J. R., Chatterjee, B., Meyer, R., Yu, J. C., Borke, J. L., Isales, C. M., Kirby, M. L., Lo, C. W. & Bollag, R. J., Jun 1 2004, In : Calcified Tissue International. 74, 6, p. 561-573 13 p.

Research output: Contribution to journalArticle

Connexin 43
Osteoblasts
Gap Junctions
Binding Sites
Down-Regulation
29 Citations (Scopus)

The LTR enhancer of ERV-9 human endogenous retrovirus is active in oocytes and progenitor cells in transgenic zebrafish and humans

Pi, W., Yang, Z., Wang, J., Ruan, L., Yu, X., Ling, J., Krantz, S., Isales, C. M., Conway, S. J., Lin, S. & Tuan Lo, D., Jan 20 2004, In : Proceedings of the National Academy of Sciences of the United States of America. 101, 3, p. 805-810 6 p.

Research output: Contribution to journalArticle

Endogenous Retroviruses
Zebrafish
Oocytes
Stem Cells
Globins
2003
13 Citations (Scopus)
Gastric Inhibitory Polypeptide
Transforming Growth Factor beta
Cell proliferation
Thymidine
Cell Proliferation
15 Citations (Scopus)
Gastric Inhibitory Polypeptide
Endothelial cells
Human Umbilical Vein Endothelial Cells
Endothelin-1
Thymidine
65 Citations (Scopus)

High glucose augments the angiotensin II-induced activation of JAK2 in vascular smooth muscle cells via the polyol pathway

Shaw, S., Wang, X., Redd, H., Alexander, G. D., Isales, C. M. & Marrero, M. B., Aug 15 2003, In : Journal of Biological Chemistry. 278, 33, p. 30634-30641 8 p.

Research output: Contribution to journalArticle

Janus Kinase 2
Vascular Smooth Muscle
Angiotensin II
Smooth Muscle Myocytes
Muscle
15 Citations (Scopus)

Negative transcriptional regulation of connexin 43 by Tbx2 in rat immature coronal sutures and ROS 17/2.8 cells in culture

Borke, J. L., Chen, J. R., Yu, J. C., Bollag, R. J., Orellana, M. F. & Isales, C. M., May 1 2003, In : Cleft Palate-Craniofacial Journal. 40, 3, p. 284-290 7 p.

Research output: Contribution to journalArticle

Connexin 43
Sutures
Cell Culture Techniques
Proteins
Cranial Sutures
6 Citations (Scopus)

Primary ovarian lymphoma manifesting with severe hypercalcemia

Rizvi, A. A., Bowman, M. A., Vaughters, R. B., Isales, C. & Mulloy, A. L., Sep 1 2003, In : Endocrine Practice. 9, 5, p. 389-393 5 p.

Research output: Contribution to journalArticle

Hypercalcemia
Lymphoma
Serum
Calcium
Confusion
17 Citations (Scopus)

Tension-Induced Reduction in Connexin 43 Expression in Cranial Sutures is Linked to Transcriptional Regulation by TBX2

Borke, J. L., Yu, J. C., Isales, C. M., Wagle, N., Do, N. N., Chen, J. R. & Bollag, R. J., Nov 1 2003, In : Annals of Plastic Surgery. 51, 5, p. 499-504 6 p.

Research output: Contribution to journalArticle

Cranial Sutures
Connexin 43
Bone and Bones
Green Fluorescent Proteins
Osteogenesis
2002
10 Citations (Scopus)

Parathyroid hormone effects on signaling pathways in endothelial cells vary with peptide concentration

Throckmorton, D., Kurscheid-Reich, D., Rosales, O. R., Rodriguez-Commes, J., Lopez, R., Sumpio, B., Zhong, Q., Ding, K., McCarthy, R., Barrett, P. Q. & Isales, C. M., Feb 11 2002, In : Peptides. 23, 1, p. 79-85 7 p.

Research output: Contribution to journalArticle

Endothelial cells
Parathyroid Hormone
Endothelial Cells
Protein Kinase C
Peptides
2001
9 Citations (Scopus)

Angiotensin II priming of aldosterone secretion with agents that enhance Ca2+ influx

Betancourt-Calle, S., Mann-Blakeney, R. S., Isales, C. M., Calle, R. A. & Bollag, W. B., May 25 2001, In : Molecular and Cellular Endocrinology. 177, 1-2, p. 61-70 10 p.

Research output: Contribution to journalArticle

Aldosterone
Angiotensin II
Phosphorylation
Saralasin
Protein Kinase C
35 Citations (Scopus)

Differential effects of agonists of aldosterone secretion on steroidogenic acute regulatory phosphorylation

Betancourt-Calle, S., Calle, R. A., Isales, C. M., White, S., Rasmussen, H. & Bollag, W. B., Feb 22 2001, In : Molecular and Cellular Endocrinology. 173, 1-2, p. 87-94 8 p.

Research output: Contribution to journalArticle

Phosphorylation
Aldosterone
Tetradecanoylphorbol Acetate
Angiotensin II
Adrenocorticotropic Hormone

Functional analysis of glucose-dependent insulinotropic polypeptide fusion proteins

Ding, K., Isales, C. M., Zhong, Q. & Bollag, R. J., Apr 30 2001, In : Peptides. 22, 4, p. 575-582 8 p.

Research output: Contribution to journalArticle

Functional analysis
Fusion reactions
Glucose
Peptides
Green Fluorescent Proteins
98 Citations (Scopus)

Glucose-dependent insulinotropic peptide is an integrative hormone with osteotropic effects

Bollag, R. J., Zhong, Q., Ding, K. H., Phillips, P., Zhong, L., Qin, F., Cranford, J., Mulloy, A. L., Cameron, R. & Isales, C. M., May 25 2001, In : Molecular and Cellular Endocrinology. 177, 1-2, p. 35-41 7 p.

Research output: Contribution to journalArticle

Gastric Inhibitory Polypeptide
Hormones
Bone
Nutrients
Bone and Bones
43 Citations (Scopus)

Microarray analysis of Tbx2-directed gene expression: A possible role in osteogenesis

Chen, J. R., Zhong, Q., Wang, J., Cameron, R. S., Borke, J. L., Isales, C. M. & Bollag, R. J., May 25 2001, In : Molecular and Cellular Endocrinology. 177, 1-2, p. 43-54 12 p.

Research output: Contribution to journalArticle

Microarray Analysis
Microarrays
Osteogenesis
Gene expression
Genes
2000
35 Citations (Scopus)

Functional parathyroid hormone receptors are present in an umbilical vein endothelial cell line

Isales, C. M., Sumpio, B., Bollag, R. J., Zhong, Q., Ding, K., Du, W., Rodriguez-Commes, J., Lopez, R., Rosales, O. R., Gasalla-Herraiz, J., McCarthy, R. & Barrett, P. Q., Oct 4 2000, In : American Journal of Physiology - Endocrinology and Metabolism. 279, 3 42-3

Research output: Contribution to journalArticle

Parathyroid Hormone Receptors
Umbilical Veins
Parathyroid Hormone
Endothelial Cells
Cell Line
37 Citations (Scopus)

Glucose-dependent insulinotropic peptide signaling pathways in endothelial cells

Zhong, Q., Bollag, R. J., Dransfield, D. T., Gasalla-Herraiz, J., Ding, K. H., Min, L. & Isales, C. M., Nov 8 2000, In : Peptides. 21, 9, p. 1427-1432 6 p.

Research output: Contribution to journalArticle

Gastric Inhibitory Polypeptide
Endothelial cells
Endothelial Cells
Peptide Receptors
Calcium Signaling
166 Citations (Scopus)

Osteoblast-derived cells express functional glucose-dependent insulinotropic peptide receptors

Bollag, R. J., Zhong, Q., Phillips, P., Min, L., Zhong, L., Cameron, R., Mulloy, A. L., Rasmussen, H., Qin, F., Ding, K. H. & Isales, C. M., Jan 1 2000, In : Endocrinology. 141, 3, p. 1228-1235 8 p.

Research output: Contribution to journalArticle

Gastric Inhibitory Polypeptide
Peptide Receptors
Osteoblasts
Incretins
Bone and Bones
1999
57 Citations (Scopus)
Hydroxybutyrates
Ketone Bodies
Diabetic Ketoacidosis
Endothelin-1
Vascular Endothelial Growth Factor A
1998
8 Citations (Scopus)

Fenfluramine potentiates canine pulmonary vasoreactivity to endothelin-1

Barman, S. A. & Isales, C. M., Jan 1 1998, In : Pulmonary Pharmacology and Therapeutics. 11, 2-3, p. 183-187 5 p.

Research output: Contribution to journalArticle

Fenfluramine
Endothelin-1
Canidae
Lung
Pulmonary Circulation
11 Citations (Scopus)

Overexpression of protein kinase C α and β1 has distinct effects on bovine aortic endothelial cell growth

Rosales, O. R., Isales, C. M. & Bhargava, J., Sep 1 1998, In : Cellular Signalling. 10, 8, p. 589-597 9 p.

Research output: Contribution to journalArticle

Protein Kinase C
Endothelial Cells
Growth
Cell Cycle
Complementary DNA
19 Citations (Scopus)

pH-dependent fluoride transport in intestinal brush border membrane vesicles

He, H., Ganapathy, V., Isales, C. M. & Whitford, G. M., Jul 17 1998, In : Biochimica et Biophysica Acta - Biomembranes. 1372, 2, p. 244-254 11 p.

Research output: Contribution to journalArticle

4-Chloromercuribenzenesulfonate
Brushes
Microvilli
Fluorides
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid
22 Citations (Scopus)

Sustained phospholipase D activation in response to angiotensin II but not carbachol in bovine adrenal glomerulosa cells

Jung, E. M., Betancourt-Calle, S., Mann-Blakeney, R. S., Foushee, T., Isales, C. M. & Bollag, W. B., Feb 15 1998, In : Biochemical Journal. 330, 1, p. 445-451 7 p.

Research output: Contribution to journalArticle

Zona Glomerulosa
Phospholipase D
Carbachol
Angiotensin II
Chemical activation
7 Citations (Scopus)

Vasopressin-induced activation of protein kinase C in renal epithelial cells

Ali, N., Kantachuvesiri, S., Smallwood, J. I., Macala, L. J., Isales, C. M., Ji, J., Reilly, R. & Hayslett, J. P., Mar 27 1998, In : Biochimica et Biophysica Acta - Molecular Cell Research. 1402, 2, p. 188-196 9 p.

Research output: Contribution to journalArticle

Arginine Vasopressin
Vasopressins
Protein Kinase C
Protein Isoforms
Epithelial Cells
1997
15 Citations (Scopus)
Protein-Tyrosine Kinases
Canidae
Serotonin
Compliance
Blood Vessels
42 Citations (Scopus)

Exposure of endothelial cells to cyclic strain induces elevations of cytosolic Ca 2+ concentration through mobilization of intracellular and extracellular pools

Rosales, O. R., Isales, C. M., Barrett, P. Q., Brophy, C. & Sumpio, B. E., Sep 1 1997, In : Biochemical Journal. 326, 2, p. 385-392 8 p.

Research output: Contribution to journalArticle

Endothelial cells
Endothelial Cells
Membranes
Aequorin
Charybdotoxin
76 Citations (Scopus)

Expression of inducible nitric oxide synthase in breast cancer correlates with metastatic disease

Dueñas-Gonzalez, A., Isales, C. M., Del Mar Abad-Hernandez, M., Gonzalez-Sarmiento, R., Sangueza, O. & Rodriguez-Commes, J., Jul 1 1997, In : Modern Pathology. 10, 7, p. 645-649 5 p.

Research output: Contribution to journalArticle

Nitric Oxide Synthase Type II
Nitric Oxide Synthase
Breast Neoplasms
Neoplasms
Neoplasm Metastasis
26 Citations (Scopus)

Inhibition of muscarinic-stimulated polyphosphoinositide hydrolysis and Ca2+ mobilization in cat iris sphincter smooth muscle cells by cAMP-elevating agents

Ding, K., Husain, S., Akhtar, R. A., Isales, C. M. & Abdel-Latif, A. A., Sep 1 1997, In : Cellular Signalling. 9, 6, p. 411-421 11 p.

Research output: Contribution to journalArticle

Phosphatidylinositol Phosphates
Carbachol
Iris
Cholinergic Agents
Smooth Muscle Myocytes
17 Citations (Scopus)

Molecular cloning of a putative tetrodotoxin-resistant sodium channel from dog nodose ganglion neurons

Chen, J., Ikeda, S. R., Lang, W., Isales, C. M. & Wei, X., Nov 20 1997, In : Gene. 202, 1-2, p. 7-14 8 p.

Research output: Contribution to journalArticle

Nodose Ganglion
Sodium Channels
Tetrodotoxin
Molecular Cloning
Dogs
1 Citation (Scopus)

Novel effect of insulin: Insulin-stimulated Na+ transport is mediated by hydrolysis of phosphoinositides

Isales, C. M., MacAla, L. J., Rodriguez-Commes, J., Gasalla-Herraiz, J. & Hayslett, J. P., Feb 3 1997, In : Biochemical and Biophysical Research Communications. 231, 1, p. 156-159 4 p.

Research output: Contribution to journalArticle

Phosphatidylinositols
Hydrolysis
Insulin
Inositol
Signal transduction
2 Citations (Scopus)

Pancreatic fibrosis with islet cell pseudoneoplastic proliferation as a cause of hypoglycemia [6]

Sangueza, O., Wei, J. & Isales, C. M., Jan 1 1997, In : Annals of Internal Medicine. 127, 11, p. 1042-1043 2 p.

Research output: Contribution to journalLetter

Islets of Langerhans
Hypoglycemia
Hypertrophy
Pancreas
Fibrosis
1996
48 Citations (Scopus)

A midregion parathyroid hormone-related peptide mobilizes cytosolic calcium and stimulates formation of inositol trisphosphate in a squamous carcinoma cell line

Orloff, J. J., Ganz, M. B., Nathanson, M. H., Moyer, M. S., Kats, Y., Mitnick, M., Behal, A., Gasalla-Herraiz, J. & Isales, C. M., Jan 1 1996, In : Endocrinology. 137, 12, p. 5376-5385 10 p.

Research output: Contribution to journalArticle

Parathyroid Hormone-Related Protein
Inositol
Squamous Cell Carcinoma
Calcium
Cell Line
122 Citations (Scopus)

Tauroursodeoxycholic acid activates protein kinase C in isolated rat hepatocytes

Beuers, U., Throckmorton, D. C., Anderson, M. S., Isales, C. M., Thasler, W., Kullak- Ublick, G. A., Sauter, G., Koebe, H. G., Paumgartner, G. & Boyer, J. L., Jan 1 1996, In : Gastroenterology. 110, 5, p. 1553-1563 11 p.

Research output: Contribution to journalArticle

Protein Kinase C
Hepatocytes
Exocytosis
Isoenzymes
Ursodeoxycholic Acid
1995
31 Citations (Scopus)

Adenosine stimulation of Na+ transport is mediated by an A1 receptor and a [Ca2+]i-dependent mechanism

Hayslett, J. P., Macala, L. J., Smallwood, J. I., Kalghatgi, L., Gasalla-Herraiz, J. & Isales, C. M., Jan 1 1995, In : Kidney International. 47, 6, p. 1576-1584 9 p.

Research output: Contribution to journalArticle

Adenosine
Signal Transduction
Sodium
Trifluoperazine
Ion Transport
15 Citations (Scopus)

Calcium Sensitive Probes for the Measurement of Intracellular Calcium: Effects of Buffer System and Magnesium Concentration

Gasalla-Herraiz, J., Rhee, S. & Isales, C. M., Jan 1 1995, In : Biochemical and Biophysical Research Communications. 214, 2, p. 373-388 16 p.

Research output: Contribution to journalArticle

Fura-2
Aequorin
Magnesium
Buffers
Calcium
106 Citations (Scopus)

Diacylglycerol production, ca2+ influx, and proteinkinase c activation in sustained cellular responses

Rasmussen, H., Isales, C. M., Calle, R., Throckmorton, D., Gasalla-Herraiz, J., Anderson, M. & McCARTHY, R., Jan 1 1995, In : Endocrine Reviews. 16, 5, p. 649-681 33 p.

Research output: Contribution to journalArticle

Diglycerides
Protein Kinase C
Transducers
Phosphotransferases
Programmed Instruction
30 Citations (Scopus)

Kinase activation and smooth muscle contraction in the presence and absence of calcium

Whitney, G., Throckmorton, D., Isales, C. M., Takuwa, Y., Yeh, J., Rasmussen, H. & Brophy, C., Jan 1 1995, In : Journal of Vascular Surgery. 22, 1, p. 37-44 8 p.

Research output: Contribution to journalArticle

Phorbol 12,13-Dibutyrate
Muscle Contraction
Vascular Smooth Muscle
Protein Kinase C
Smooth Muscle
4 Citations (Scopus)

Parathyroid Hormone Stimulates Electrogenic Sodium Transport in A6 Cells

Rodriguezcommes, J., Forrest, J. N., Lopez, R., Gasallaherraiz, J. & Isales, C. M., Jan 1 1995, In : Biochemical and Biophysical Research Communications. 213, 2, p. 688-698 11 p.

Research output: Contribution to journalArticle

Parathyroid Hormone
Sodium
Calcium
Nitrendipine
Calcium Channel Blockers
25 Citations (Scopus)

Vasopressin-stimulated electrogenic sodium transport in a6 cells is linked to a Ca2+-mobilizing signal mechanism

Hayslett, J. P., Macala, L. J., Smallwood, J. I., Kalghatgi, L., Gassala-Herraiz, J. & Isales, C. M., Jul 7 1995, In : Journal of Biological Chemistry. 270, 27, p. 16082-16088 7 p.

Research output: Contribution to journalArticle

Arginine Vasopressin
Vasopressins
Sodium
Adenylyl Cyclases
Chemical activation
1994
19 Citations (Scopus)

Atrial natriuretic peptide enhances activity of potassium conductance in adrenal glomerulosa cells

Ganz, M. B., Nee, J. J., Isales, C. M. & Barrett, P. Q., May 13 1994, In : AM.J.PHYSIOL.. 266, 5 part 1, p. 1357-1365 9 p.

Research output: Contribution to journalArticle

Zona Glomerulosa
Atrial Natriuretic Factor
Potassium
Atrial Natriuretic Factor Receptors
Aldosterone
27 Citations (Scopus)

Mechanism of insulin-stimulated electrogenic sodium transport

Rodriguez-Commes, J., Isales, C. M., Kalghati, L., Gasalla-Herraiz, J. & Hayslett, J. P., Jan 1 1994, In : Kidney International. 46, 3, p. 666-674 9 p.

Research output: Contribution to journalArticle

Sodium
Insulin
Aldosterone
Trifluoperazine
Calcium-Calmodulin-Dependent Protein Kinases
1993
22 Citations (Scopus)

Endothelin-1 induces cholestasis which is mediated by an increase in portal pressure

Isales, C. M., Nathanson, M. H. & Bruck, R., Mar 31 1993, In : Biochemical and Biophysical Research Communications. 191, 3, p. 1244-1251 8 p.

Research output: Contribution to journalArticle

Portal Pressure
Cholestasis
Endothelin-1
Perfusion
Pressure
43 Citations (Scopus)

Phospholipase C: A Putative Mechanotransducer for Endothelial Cell Response to Acute Hemodynamic Changes

Brophy, C. M., Mills, I., Rosales, O., Isales, C. M. & Sumpio, B. E., Jan 1 1993, In : Biochemical and Biophysical Research Communications. 190, 2, p. 576-581 6 p.

Research output: Contribution to journalArticle

Endothelial cells
Hemodynamics
Type C Phospholipases
Endothelial Cells
Signal transduction
21 Citations (Scopus)

Platelet cytosolic calcium, peripheral hemodynamics, and vasodilatory peptides in liver cirrhosis

Rodríguez-pérez, F., Isales, C. M. & Groszmann, R. J., Jan 1 1993, In : Gastroenterology. 105, 3, p. 863-867 5 p.

Research output: Contribution to journalArticle

Liver Cirrhosis
Blood Platelets
Hemodynamics
Calcium
Peptides
137 Citations (Scopus)

Tauroursodeoxycholic acid stimulates hepatocellular exocytosis and mobilizes extracellular Ca++ mechanisms defective in cholestasis

Beuers, U., Nathanson, M. H., Isales, C. M. & Boyer, J. L., Jan 1 1993, In : Journal of Clinical Investigation. 92, 6, p. 2984-2993 10 p.

Research output: Contribution to journalArticle

Cholestasis
Exocytosis
Hepatocytes
Bile
Liver
46 Citations (Scopus)

T-type calcium channels in adrenal glomerulosa cells: GTP-dependent modulation by angiotensin II

McCarthy, R. T., Isales, C. M. & Rasmussen, H., Jan 1 1993, In : Proceedings of the National Academy of Sciences of the United States of America. 90, 8, p. 3260-3264 5 p.

Research output: Contribution to journalArticle

T-Type Calcium Channels
Zona Glomerulosa
Guanosine Triphosphate
Angiotensin II
Calcium Channels