Chad E. Stephens

Associate Professor

  • 2124 Citations
  • 27 h-Index

Research output per year

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Personal profile

Education/Academic qualification

University of South Carolina

Research interests

  • Medicinal Chemistry
  • Fluorination Chemistry
  • Antiprotozoals
  • Prodrugs
  • Heterocyclic Chemistry
  • Antivirals

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Research Output

Heterocyclic Diamidine DNA Ligands as HOXA9 Transcription Factor Inhibitors: Design, Molecular Evaluation, and Cellular Consequences in a HOXA9-Dependant Leukemia Cell Model

Depauw, S., Lambert, M., Jambon, S., Paul, A., Peixoto, P., Nhili, R., Marongiu, L., Figeac, M., Dassi, C., Paul-Constant, C., Billoré, B., Kumar, A., Farahat, A. A., Ismail, M. A., Mineva, E., Sweat, D. P., Stephens, C. E., Boykin, D. W., Wilson, W. D. & David-Cordonnier, M. H., Feb 14 2019, In : Journal of Medicinal Chemistry. 62, 3, p. 1306-1329 24 p.

Research output: Contribution to journalArticle

  • 5 Scopus citations

    G-quadruplex-binding small molecules ameliorate C9orf72 FTD/ALS pathology in vitro and in vivo

    Simone, R., Balendra, R., Moens, T. G., Preza, E., Wilson, K. M., Heslegrave, A., Woodling, N. S., Niccoli, T., Gilbert-Jaramillo, J., Abdelkarim, S., Clayton, E. L., Clarke, M., Konrad, M. T., Nicoll, A. J., Mitchell, J. S., Calvo, A., Chio, A., Houlden, H., Polke, J. M., Ismail, M. A. & 13 others, Stephens, C. E., Vo, T., Farahat, A. A., Wilson, W. D., Boykin, D. W., Zetterberg, H., Partridge, L., Wray, S., Parkinson, G., Neidle, S., Patani, R., Fratta, P. & Isaacs, A. M., Jan 2018, In : EMBO Molecular Medicine. 10, 1, p. 22-31 10 p.

    Research output: Contribution to journalArticle

  • 59 Scopus citations

    Isolation of 5-Hydroxy-γ-lactams from a Classical 2-Aminopyrrole Synthesis

    Suthiwangcharoen, N., Bean, A. C., Hassan, M., Eidell, C. K. & Stephens, C. E., May 1 2018, In : Journal of Heterocyclic Chemistry. 55, 5, p. 1219-1222 4 p.

    Research output: Contribution to journalArticle

  • Phenotypic evaluation and in silico ADMET properties of novel arylimidamides in acute mouse models of Trypanosoma cruzi infection

    da Silva, C. F., Batista, D. D. G. J., de Araújo, J. S., Cunha-Junior, E. F., Stephens, C. E., Banerjee, M., Farahat, A. A., Akay, S., Fisher, M. K., Boykin, D. W. & Soeiro, M. D. N. C., Apr 3 2017, In : Drug Design, Development and Therapy. 11, p. 1095-1105 11 p.

    Research output: Contribution to journalArticle

  • 4 Scopus citations

    Synthesis of 4H-3-aryl-2-cyano-1,4-benzothiazine 1,1-dioxides for antiviral studies

    Wilkerson, P. D., Bean, A. C. & Stephens, C. E., Apr 1 2017, In : Heterocyclic Communications. 23, 2, p. 101-103 3 p.

    Research output: Contribution to journalArticle

  • 1 Scopus citations


    • 1 Editorial activity

    Heterocyclic Communications (Journal)

    Chad E. Stephens (Editor)


    Activity: Editorial work typesEditorial activity