Chad E. Stephens

Associate Professor

  • 2012 Citations
  • 27 h-Index
19962019
If you made any changes in Pure, your changes will be visible here soon.

Research Output 1996 2019

Filter
Article
12 Citations (Scopus)

3,5-diarylisoxazoles: Individualized three-step synthesis and isomer determination using 13C NMR or mass spectroscopy

Stephens, C. E. & Arafa, R. K., Sep 1 2006, In : Journal of Chemical Education. 83, 9, p. 1336-1340 5 p.

Research output: Contribution to journalArticle

Chalcone
Isomers
fragmentation
Isoxazoles
Nuclear magnetic resonance
10 Citations (Scopus)

Activities of dicationic compounds against Trichomonas vaginalis

Crowell, A. L., Stephens, C. E., Kumar, A., Boykin, D. W. & Secor, W. E., Sep 1 2004, In : Antimicrobial Agents and Chemotherapy. 48, 9, p. 3602-3605 4 p.

Research output: Contribution to journalArticle

Trichomonas vaginalis
Metronidazole
Inhibitory Concentration 50
Parasites
4-nitroimidazole
48 Citations (Scopus)

Activity of "reversed" diamidines against Trypanosoma cruzi "in vitro"

Silva, C. F., Batista, M. M., Mota, R. A., de Souza, E. M., Stephens, C. E., Som, P., Boykin, D. W. & Soeiro, M. D. N. C., Jun 15 2007, In : Biochemical Pharmacology. 73, 12, p. 1939-1946 8 p.

Research output: Contribution to journalArticle

Pentamidine
Trypanosoma cruzi
Toxicity
Nifurtimox
Cells
1 Citation (Scopus)

Aerobic aromatization of 1,3,5-triarylpyrazolines in open air and without catalyst

Jenkins, R. N., Hinnant, G. M., Bean, A. C. & Stephens, C. E., Dec 7 2015, In : Arkivoc. 2015, 7, p. 347-353 7 p.

Research output: Contribution to journalArticle

Pyrazoles
Aromatization
Dimethyl Sulfoxide
Heating
Catalysts
4 Citations (Scopus)

Aerobic epoxidation and hydroxylation of a pyrrolo[2,1-b]quinazoline under ambient conditions

Hawkins, R. A. & Stephens, C. E., Nov 24 2010, In : Tetrahedron Letters. 51, 47, p. 6129-6131 3 p.

Research output: Contribution to journalArticle

Quinazolines
Hydroxylation
Pyrroles
Oxygenation
Epoxidation
27 Citations (Scopus)

An efficient synthesis of 5,5′-diaryl-2,2′-bichalcophenes

Ismail, M. A., Boykin, D. W. & Stephens, C. E., Jan 30 2006, In : Tetrahedron Letters. 47, 5, p. 795-797 3 p.

Research output: Contribution to journalArticle

Furans
Thiophenes
Light
5 Citations (Scopus)
Thiadiazines
Thiadiazoles
Carboxylic Acids
Hydrolysis
Esters
4 Citations (Scopus)

An intramolecular N-arylation approach to 3-functionalized 4,9-dihydropyrrolo[2,1-b]quinazolines

Suthiwangcharoen, N., Pochini, S. M., Sweat, D. P. & Stephens, C. E., May 1 2011, In : Journal of Heterocyclic Chemistry. 48, 3, p. 706-709 4 p.

Research output: Contribution to journalArticle

Quinazolines
phosphine
Ligands
Palladium
Electrons
3 Citations (Scopus)

Antiprion activity of DB772 and related monothiophene- and furan-based analogs in a persistently infected ovine microglia culture system

Dinkel, K. D., Stanton, J. B., Boykin, D. W., Stephens, C. E., Madsen-Bouterse, S. A. & Schneider, D. A., Sep 1 2016, In : Antimicrobial Agents and Chemotherapy. 60, 9, p. 5467-5482 16 p.

Research output: Contribution to journalArticle

Microglia
Sheep
Prions
Structure-Activity Relationship
Library Surveys
27 Citations (Scopus)

Antiviral properties of new arylsulfone derivatives with activity against human betaherpesviruses

Naesens, L., Stephens, C. E., Andrei, G., Loregian, A., De Bolle, L., Snoeck, R., Sowell, J. W. & De Clercq, E., Oct 1 2006, In : Antiviral Research. 72, 1, p. 60-67 8 p.

Research output: Contribution to journalArticle

Human Herpesvirus 6
Benzene Derivatives
Cytomegalovirus
Human Activities
Foscarnet
9 Citations (Scopus)

A quantitative reverse-transcriptase PCR assay for the assessment of drug activities against intracellular Theileria annulata schizonts

Hostettler, I., Müller, J., Stephens, C. E., Haynes, R. & Hemphill, A., Dec 1 2014, In : International Journal for Parasitology: Drugs and Drug Resistance. 4, 3, p. 201-209 9 p.

Research output: Contribution to journalArticle

Theileria annulata
Schizonts
Reverse Transcriptase Polymerase Chain Reaction
Theileria
Parasites
56 Citations (Scopus)

Arylimidamide DB766, a potential chemotherapeutic candidate for Chagas' disease treatment

Batista, D. D. G. J., Batista, M. M., De Oliveira, G. M., Do Amaral, P. B., Lannes-Vieira, J., Britto, C. C., Junqueira, A., Lima, M. M., Romanha, A. J., Sales, P. A., Stephens, C. E., Boykin, D. W. & Soeiro, M. D. N. C., Jul 1 2010, In : Antimicrobial Agents and Chemotherapy. 54, 7, p. 2940-2952 13 p.

Research output: Contribution to journalArticle

Chagas Disease
Trypanosoma cruzi
Parasites
Parasite Load
Parasitic Diseases
1 Citation (Scopus)
Pyrroles
Carboxylic Acids
Acetic Acid
Acids
phenylacetic acid
46 Citations (Scopus)

Cellular effects of reversed amidines on Trypanosoma cruzi

Silva, C. F., Meuser, M. B., De Souza, E. M., Meirelles, M. N. L., Stephens, C. E., Som, P., Boykin, D. W. & Soeiro, M. N. C., Nov 1 2007, In : Antimicrobial Agents and Chemotherapy. 51, 11, p. 3803-3809 7 p.

Research output: Contribution to journalArticle

Amidines
Trypanosoma cruzi
Pentamidine
Chagas Disease
Parasites
15 Citations (Scopus)

Characterizing the fragmentation of 2,5-bis (4-amidinophenyl)furan-bis-O-methylamidoxime and selected metabolites using ion trap mass spectrometry

Zhou, L., Voyksner, R. D., Thakker, D. R., Stephens, C. E., Anbazhagan, M., Boykin, D. W., Hall, J. E. & Tidwell, R. R., Jun 5 2002, In : Rapid Communications in Mass Spectrometry. 16, 11, p. 1078-1085 8 p.

Research output: Contribution to journalArticle

Metabolites
Mass spectrometry
Ions
Deuterium Oxide
Electrospray ionization
16 Citations (Scopus)

Combined treatment of heterocyclic analogues and benznidazole upon Trypanosoma cruzi in vivo

da Gama Jaén Batista, D., Batista, M. M., de Oliveira, G. M., Britto, C. C., Rodrigues, A. C. M., Stephens, C. E., Boykin, D. W. & de Nazaré Correia Soeiro, M., Aug 1 2011, In : PloS one. 6, 7, e22155.

Research output: Contribution to journalArticle

Trypanosoma cruzi
parasitemia
mice
therapeutics
Chagas disease
33 Citations (Scopus)

Convenient and improved halogenation of 3,5-diarylisoxazoles using N-halosuccinimides

Day, R. A., Blake, J. A. & Stephens, C. E., Jan 1 2003, In : Synthesis. 10, p. 1586-1590 5 p.

Research output: Contribution to journalArticle

Halogenation
Isoxazoles
Acetic acid
Acetic Acid
Heating
6 Citations (Scopus)

CYP1A1 and CYP1B1-mediated biotransformation of the antitrypanosomal methamidoxime prodrug DB844 forms novel metabolites through intramolecular rearrangement

Ju, W., Yang, S., Ansede, J. H., Stephens, C. E., Bridges, A. S., Voyksner, R. D., Ismail, M. A., Boykin, D. W., Tidwell, R. R., Hall, J. E. & Wang, M. Z., Jan 1 2014, In : Journal of Pharmaceutical Sciences. 103, 1, p. 337-349 13 p.

Research output: Contribution to journalArticle

Cytochrome P-450 CYP1A1
Prodrugs
Biotransformation
Nitric Oxide
Amidines
69 Citations (Scopus)

CYP4F enzymes are the major enzymes in human liver microsomes that catalyze the O-demethylation of the antiparasitic prodrug DB289 [2,5-bis(4- amidinophenyl)furan-bis-O-methylamidoxime]

Wang, M. Z., Saulter, J. Y., Usuki, E., Cheung, Y. L., Hall, M., Bridges, A. S., Loewen, G., Parkinson, O. T., Stephens, C. E., Allen, J. L., Zeldin, D. C., Boykin, D. W., Tidwell, R. R., Parkinson, A., Paine, M. F. & Hall, J. E., Dec 1 2006, In : Drug Metabolism and Disposition. 34, 12, p. 1985-1994 10 p.

Research output: Contribution to journalArticle

Antiparasitic Agents
Prodrugs
Liver Microsomes
Enzymes
Cytochrome-B(5) Reductase
43 Citations (Scopus)

Detection of inhibition of bovine viral diarrhea virus by aromatic cationic molecules

Givens, M. D., Dykstra, C. C., Brock, K. V., Stringfellow, D. A., Kumar, A., Stephens, C. E., Goker, H. & Boykin, D. W., Jul 1 2003, In : Antimicrobial Agents and Chemotherapy. 47, 7, p. 2223-2230 8 p.

Research output: Contribution to journalArticle

Bovine Viral Diarrhea Viruses
Hepacivirus
RNA Viruses
Drug Discovery
Cell Culture Techniques
24 Citations (Scopus)

Di-cationic arylimidamides act against Neospora caninum tachyzoites by interference in membrane structure and nucleolar integrity and are active against challenge infection in mice

Schorer, M., Debache, K., Barna, F., Monney, T., Müller, J., Boykin, D. W., Stephens, C. E. & Hemphill, A., Dec 1 2012, In : International Journal for Parasitology: Drugs and Drug Resistance. 2, p. 109-120 12 p.

Research output: Contribution to journalArticle

Neospora
Membranes
Infection
Parasites
Pentamidine
135 Citations (Scopus)

Dications that target the DNA minor groove: Compound design and preparation, DNA interactions, cellular distribution and biological activity

Wilson, W. D., Nguyen, B., Tanious, F. A., Mathis, A., Hall, J. E., Stephens, C. E. & Boykin, D. W., Jul 1 2005, In : Current Medicinal Chemistry - Anti-Cancer Agents. 5, 4, p. 389-408 20 p.

Research output: Contribution to journalArticle

Pentamidine
Kinetoplast DNA
DNA
Circular DNA
Thiophenes
129 Citations (Scopus)

Diguanidino and "reversed" diamidino 2,5-diarylfurans as antimicrobial agents

Stephens, C. E., Tanious, F., Kim, S., Wilson, W. D., Schell, W. A., Perfect, J. R., Franzblau, S. G. & Boykin, D. W., May 24 2001, In : Journal of Medicinal Chemistry. 44, 11, p. 1741-1748 8 p.

Research output: Contribution to journalArticle

Furans
Anti-Infective Agents
Rhizopus
Cryptococcus neoformans
Aspergillus fumigatus
13 Citations (Scopus)

Direct Conversion of Amidoximes to Amidines via Transfer Hydrogenation

Anbazhagan, M., Boykin, D. W. & Stephens, C. E., Jan 1 2003, In : Synthesis. 16, p. 2467-2469 3 p.

Research output: Contribution to journalArticle

formic acid
Amidines
Acetic acid
Acetic Acid
Hydrogenation
64 Citations (Scopus)

Distribution of furamidine analogues in tumor cells: Influence of the number of positive charges

Lansiaux, A., Dassonneville, L., Facompré, M., Kumar, A., Stephens, C. E., Bajic, M., Tanious, F., Wilson, D. W., Boykin, D. W. & Bailly, C., May 9 2002, In : Journal of Medicinal Chemistry. 45, 10, p. 1994-2002 9 p.

Research output: Contribution to journalArticle

Cell Count
Cell Nucleus
Amidines
DNA
Neoplasms
61 Citations (Scopus)

Distribution of furamidine analogues in tumor cells: Targeting of the nucleus or mitochondria depending on the amidine substitution

Lansiaux, A., Tanious, F., Mishal, Z., Dassonneville, L., Kumar, A., Stephens, C. E., Hu, Q., Wilson, W. D., Boykin, D. W. & Bailly, C., Dec 15 2002, In : Cancer Research. 62, 24, p. 7219-7229 11 p.

Research output: Contribution to journalArticle

Amidines
Cell Nucleus
Mitochondria
DNA
Pentamidine
29 Citations (Scopus)

DNA Minor Groove Induced Dimerization of Heterocyclic Cations: Compound Structure, Binding Affinity, and Specificity for a TTAA Site

Munde, M., Kumar, A., Nhili, R., Depauw, S., David-Cordonnier, M. H., Ismail, M. A., Stephens, C. E., Farahat, A. A., Batista-Parra, A., Boykin, D. W. & Wilson, W. D., Oct 8 2010, In : Journal of Molecular Biology. 402, 5, p. 847-864 18 p.

Research output: Contribution to journalArticle

Heterocyclic Compounds
Dimerization
Pentamidine
Cations
CD-I
16 Citations (Scopus)

Evaluation of arylimidamides DB1955 and DB1960 as candidates against visceral leishmaniasis and Chagas' disease: In vivo efficacy, acute toxicity, pharmacokinetics, and toxicology studies

Zhu, X., Liu, Q., Yang, S., Parman, T., Green, C. E., Mirsalis, J. C., Soeiro, M. D. N. C., De Souza, E. M., Da Silva, C. F., Batista, D. D. G. J., Stephens, C. E., Banerjee, M., Farahat, A. A., Munde, M., Wilson, W. D., Boykin, D. W., Wang, M. Z. & Werbovetz, K. A., Jul 1 2012, In : Antimicrobial Agents and Chemotherapy. 56, 7, p. 3690-3699 10 p.

Research output: Contribution to journalArticle

Visceral Leishmaniasis
Parasitemia
Chagas Disease
Toxicology
Pharmacokinetics
67 Citations (Scopus)

Evaluation of the influence of compound structure on stacked-dimer formation in the DNA minor groove

Wang, L., Carrasco, C., Kumar, A., Stephens, C. E., Bailly, C., Boykin, D. W. & Wilson, W. D., Feb 27 2001, In : Biochemistry. 40, 8, p. 2511-2521 11 p.

Research output: Contribution to journalArticle

Amidines
Dimers
DNA
Human Genome Project
Nucleotide Motifs
23 Citations (Scopus)

Experimental treatment of Neospora caninum-infected mice with the arylimidamide DB750 and the thiazolide nitazoxanide

Debache, K., Guionaud, C., Kropf, C., Boykin, D., Stephens, C. E. & Hemphill, A., Oct 1 2011, In : Experimental Parasitology. 129, 2, p. 95-100 6 p.

Research output: Contribution to journalArticle

nitazoxanide
Neospora
Infection
Intraperitoneal Injections
Therapeutics
34 Citations (Scopus)

G-quadruplex-binding small molecules ameliorate C9orf72 FTD/ALS pathology in vitro and in vivo

Simone, R., Balendra, R., Moens, T. G., Preza, E., Wilson, K. M., Heslegrave, A., Woodling, N. S., Niccoli, T., Gilbert-Jaramillo, J., Abdelkarim, S., Clayton, E. L., Clarke, M., Konrad, M. T., Nicoll, A. J., Mitchell, J. S., Calvo, A., Chio, A., Houlden, H., Polke, J. M., Ismail, M. A. & 13 others, Stephens, C. E., Vo, T., Farahat, A. A., Wilson, W. D., Boykin, D. W., Zetterberg, H., Partridge, L., Wray, S., Parkinson, G., Neidle, S., Patani, R., Fratta, P. & Isaacs, A. M., Jan 1 2018, In : EMBO Molecular Medicine. 10, 1, p. 22-31 10 p.

Research output: Contribution to journalArticle

G-Quadruplexes
Dipeptides
Pathology
Motor Neurons
RNA
1 Citation (Scopus)

Heterocyclic Diamidine DNA Ligands as HOXA9 Transcription Factor Inhibitors: Design, Molecular Evaluation, and Cellular Consequences in a HOXA9-Dependant Leukemia Cell Model

Depauw, S., Lambert, M., Jambon, S., Paul, A., Peixoto, P., Nhili, R., Marongiu, L., Figeac, M., Dassi, C., Paul-Constant, C., Billoré, B., Kumar, A., Farahat, A. A., Ismail, M. A., Mineva, E., Sweat, D. P., Stephens, C. E., Boykin, D. W., Wilson, W. D. & David-Cordonnier, M. H., Feb 14 2019, In : Journal of Medicinal Chemistry. 62, 3, p. 1306-1329 24 p.

Research output: Contribution to journalArticle

Pentamidine
Leukemia
Transcription Factors
Ligands
DNA
18 Citations (Scopus)

Heterocyclic diamidine interactions at AT base Pairs in the DNA minor groove: Effects of heterocycle differences, DNA AT sequence and length

Liu, Y., Collar, C. J., Kumar, A., Stephens, C. E., Boykin, D. W. & Wilson, W. D., Sep 18 2008, In : Journal of Physical Chemistry B. 112, 37, p. 11809-11818 10 p.

Research output: Contribution to journalArticle

Pentamidine
DNA sequences
Amidines
grooves
DNA
30 Citations (Scopus)

Host cells participate in the in vitro effects of novel diamidine analogues against tachyzoites of the intracellular apicomplexan parasites Neospora caninum and Toxoplasma gondii

Leepin, A., Stüdli, A., Brun, R., Stephens, C. E., Boykin, D. W. & Hemphill, A., Jun 1 2008, In : Antimicrobial Agents and Chemotherapy. 52, 6, p. 1999-2008 10 p.

Research output: Contribution to journalArticle

Neospora
Pentamidine
Toxoplasma
Parasites
Pharmaceutical Preparations
16 Citations (Scopus)

Inhibition by dications of in vitro growth of Leishmania major and Leishmania tropica: Causative agents of old world cutaneous leishmaniasis

Rosypal, A. C., Werbovetz, K. A., Salem, M., Stephens, C. E., Kumar, A., Boykin, D. W., Hall, J. E. & Tidwell, R. R., Jun 1 2008, In : Journal of Parasitology. 94, 3, p. 743-749 7 p.

Research output: Contribution to journalArticle

amidines
Leishmania tropica
Amidines
leishmaniasis
Leishmania major
10 Citations (Scopus)

Inhibition of In Vitro Intracellular Growth of Trypanosoma cruzi by Dicationic Compounds

Rowland, E. C., Moore-Lai, D., Seed, J. R., Stephens, C. E. & Boykin, D. W., Oct 1 2003, In : Journal of Parasitology. 89, 5, p. 1078-1080 3 p.

Research output: Contribution to journalArticle

Trypanosoma cruzi
parasite
Parasites
parasites
drug
11 Citations (Scopus)

Inhibitory effect of dicationic diphenylfurans on production of type I collagen by human fibroblasts and activated hepatic stellate cells

Stefanovic, L., Stephens, C. E., Boykin, D. & Stefanovic, B., Mar 11 2005, In : Life Sciences. 76, 17, p. 2011-2026 16 p.

Research output: Contribution to journalArticle

Hepatic Stellate Cells
Fibroblasts
Protein Sorting Signals
Collagen Type I
Procollagen
12 Citations (Scopus)

In vitro activity and preliminary toxicity of various diamidine compounds against Trypanosoma evansi

Gillingwater, K., Kumar, A., Ismail, M. A., Arafa, R. K., Stephens, C. E., Boykin, D. W., Tidwell, R. R. & Brun, R., May 1 2010, In : Veterinary Parasitology. 169, 3-4, p. 264-272 9 p.

Research output: Contribution to journalArticle

Pentamidine
Trypanosoma
Trypanosoma evansi
toxicity
Trypanosoma rhodesiense
12 Citations (Scopus)

In vitro activity of dicationic compounds against a North American foxhound isolate of Leishmania infantum

Rosypal, A. C., Hall, J. E., Bakunova, S., Patrick, D. A., Bakunov, S., Stephens, C. E., Kumar, A., Boykin, D. W. & Tidwell, R. R., Apr 30 2007, In : Veterinary Parasitology. 145, 3-4, p. 207-216 10 p.

Research output: Contribution to journalArticle

Leishmania infantum
Pentamidine
leishmaniasis
amidines
Leishmaniasis
17 Citations (Scopus)

In Vitro and in vivo activities of dicationic diguanidino compounds against echinococcus multilocularis metacestodes

Küster, T., Kriegel, N., Boykin, D. W., Stephens, C. E. & Hemphill, A., Aug 1 2013, In : Antimicrobial Agents and Chemotherapy. 57, 8, p. 3829-3835 7 p.

Research output: Contribution to journalArticle

Echinococcus multilocularis
Benzimidazoles
Thiophenes
Mebendazole
Furans
5 Citations (Scopus)

In vitro and in vivo studies of the biological activity of novel arylimidamides against Trypanosoma cruzi

De Araújo, J. S., Da Silva, C. F., Batista, D. G. J., Da Silva, P. B., Meuser, M. B., Aiub, C. A. F., Da Silva, M. F. V., Araújo-Lima, C. F., Banerjee, M., Farahat, A. A., Stephens, C. E., Kumar, A., Boykin, D. W. & Soeiro, M. N. C., Jan 1 2014, In : Antimicrobial Agents and Chemotherapy. 58, 7, p. 4191-4195 5 p.

Research output: Contribution to journalArticle

Trypanosoma cruzi
Parasitemia
Mortality
In Vitro Techniques
19 Citations (Scopus)

In vitro effects of arylimidamides against Besnoitia besnoiti infection in Vero cells.

Cortes, H. C., Muller, N., Boykin, D., Stephens, C. E. & Hemphill, A., Apr 1 2011, In : Parasitology. 138, 5, p. 583-592 10 p.

Research output: Contribution to journalArticle

Sarcocystidae
Besnoitia besnoiti
Vero Cells
tachyzoites
Real-Time Polymerase Chain Reaction
27 Citations (Scopus)

In vitro efficacy of dicationic compounds and mefloquine enantiomers against Echinococcus multilocularis metacestodes

Stadelmann, B., Küster, T., Scholl, S., Barna, F., Kropf, C., Keiser, J., Boykin, D. W., Stephens, C. E. & Hemphill, A., Oct 1 2011, In : Antimicrobial Agents and Chemotherapy. 55, 10, p. 4866-4872 7 p.

Research output: Contribution to journalArticle

Echinococcus multilocularis
Mefloquine
nitazoxanide
Benzimidazoles
Glucose-6-Phosphate Isomerase
13 Citations (Scopus)

In vitro trypanocidal activity of DB745B and other novel arylimidamides against Trypanosoma cruzi

da Silva, C. F., Junqueira, A., Lima, M. M., Romanha, A. J., Sales Junior, P. A., Stephens, C. E., Som, P., Boykin, D. W. & de Nazaré Correia Soeiro, M., Jun 1 2011, In : Journal of Antimicrobial Chemotherapy. 66, 6, p. 1295-1297 3 p., dkr140.

Research output: Contribution to journalArticle

Trypanosoma cruzi
Inhibitory Concentration 50
Trypanocidal Agents
Gentian Violet
Blood Banks

Isolation of 5-Hydroxy-γ-lactams from a Classical 2-Aminopyrrole Synthesis

Suthiwangcharoen, N., Bean, A. C., Hassan, M., Eidell, C. K. & Stephens, C. E., May 1 2018, In : Journal of Heterocyclic Chemistry. 55, 5, p. 1219-1222 4 p.

Research output: Contribution to journalArticle

Lactams
Byproducts
Condensation
28 Citations (Scopus)

Large, sequence-dependent effects on DNA conformation by minor groove binding compounds

Tevis, D. S., Kumar, A., Stephens, C. E., Boykin, D. W. & Wilson, W. D., Jul 3 2009, In : Nucleic Acids Research. 37, 16, p. 5550-5558 9 p., gkp558.

Research output: Contribution to journalArticle

Nucleic Acid Conformation
Netropsin
Kinetoplast DNA
Amidines
Pentamidine
4 Citations (Scopus)

Mono- and trifluorination of the thiazole ring of 2,5-diarylthiazoles using N-fluorobenzenesulfonimide (NFSI)

Hatfield, J. M., Eidell, C. K. & Stephens, C. E., Feb 20 2013, In : Tetrahedron Letters. 54, 8, p. 1025-1028 4 p.

Research output: Contribution to journalArticle

Thiazoles
Fluorination
Halogenation
Crystal structure
X-Rays
51 Citations (Scopus)

Novel arylimidamides for treatment of visceral leishmaniasis

Wang, M. Z., Zhu, X., Srivastava, A., Liu, Q., Sweat, J. M., Pandharkar, T., Stephens, C. E., Riccio, E., Parman, T., Munde, M., Mandal, S., Madhubala, R., Tidwell, R. R., Wilson, W. D., Boykin, D. W., Hall, J. E., Kyle, D. E. & Werbovetz, K. A., Jun 1 2010, In : Antimicrobial Agents and Chemotherapy. 54, 6, p. 2507-2516 10 p.

Research output: Contribution to journalArticle

Visceral Leishmaniasis
Leishmania donovani
Parasitemia
Cricetinae
Inhibitory Concentration 50
12 Citations (Scopus)

Nuclear fluorination of 2,4-diarylthiazoles with Accufluor®

Campbell, T. F. & Stephens, C. E., Dec 1 2006, In : Journal of Fluorine Chemistry. 127, 12, p. 1591-1594 4 p.

Research output: Contribution to journalArticle

Thiazoles
Fluorination
fluorination
Halogenation
chromatography
17 Citations (Scopus)

Nuclear fluorination of 3,5-diarylisoxazoles with Selectfluor®

Stephens, C. E. & Blake, J. A., Dec 1 2004, In : Journal of Fluorine Chemistry. 125, 12, p. 1939-1945 7 p.

Research output: Contribution to journalArticle

Fluorination
fluorination
Halogenation
Temperature
acetonitrile