Chad E. Stephens

Associate Professor

  • 2091 Citations
  • 27 h-Index
19962019

Research output per year

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Research Output

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Article
2005

Inhibitory effect of dicationic diphenylfurans on production of type I collagen by human fibroblasts and activated hepatic stellate cells

Stefanovic, L., Stephens, C. E., Boykin, D. & Stefanovic, B., Mar 11 2005, In : Life sciences. 76, 17, p. 2011-2026 16 p.

Research output: Contribution to journalArticle

11 Scopus citations

Synthesis, DNA affinity, and antiprotozoal activity of fused ring dicationic compounds and their prodrugs

Arafa, R. K., Brun, R., Wenzler, T., Tanious, F. A., Wilson, W. D., Stephens, C. E. & Boykin, D. W., Aug 25 2005, In : Journal of Medicinal Chemistry. 48, 17, p. 5480-5488 9 p.

Research output: Contribution to journalArticle

60 Scopus citations

Unusual dehydroxylation of antimicrobial amidoxime prodrugs by cytochrome b5 and NADH cytochrome b5 reductase

Saulter, J. Y., Kurian, J. R., Trepanier, L. A., Tidwell, R. R., Bridges, A. S., Boykin, D. W., Stephens, C. E., Anbazhagan, M. & Hall, J. E., Dec 1 2005, In : Drug Metabolism and Disposition. 33, 12, p. 1886-1893 8 p.

Research output: Contribution to journalArticle

41 Scopus citations
2004

Activities of dicationic compounds against Trichomonas vaginalis

Crowell, A. L., Stephens, C. E., Kumar, A., Boykin, D. W. & Secor, W. E., Sep 1 2004, In : Antimicrobial agents and chemotherapy. 48, 9, p. 3602-3605 4 p.

Research output: Contribution to journalArticle

10 Scopus citations

Nuclear fluorination of 3,5-diarylisoxazoles with Selectfluor®

Stephens, C. E. & Blake, J. A., Dec 1 2004, In : Journal of Fluorine Chemistry. 125, 12, p. 1939-1945 7 p.

Research output: Contribution to journalArticle

18 Scopus citations

Synthesis of Benzyloxybromobenzonitriles

Ismail, M. A., Anbazhagan, M., Stephens, C. E. & Boykin, D. W., Mar 31 2004, In : Synthetic Communications. 34, 5, p. 751-758 8 p.

Research output: Contribution to journalArticle

3 Scopus citations
2003

Convenient and improved halogenation of 3,5-diarylisoxazoles using N-halosuccinimides

Day, R. A., Blake, J. A. & Stephens, C. E., Jan 1 2003, In : Synthesis. 10, p. 1586-1590 5 p.

Research output: Contribution to journalArticle

35 Scopus citations

Detection of inhibition of bovine viral diarrhea virus by aromatic cationic molecules

Givens, M. D., Dykstra, C. C., Brock, K. V., Stringfellow, D. A., Kumar, A., Stephens, C. E., Goker, H. & Boykin, D. W., Jul 1 2003, In : Antimicrobial agents and chemotherapy. 47, 7, p. 2223-2230 8 p.

Research output: Contribution to journalArticle

43 Scopus citations

Direct Conversion of Amidoximes to Amidines via Transfer Hydrogenation

Anbazhagan, M., Boykin, D. W. & Stephens, C. E., Jan 1 2003, In : Synthesis. 16, p. 2467-2469 3 p.

Research output: Contribution to journalArticle

13 Scopus citations

Inhibition of In Vitro Intracellular Growth of Trypanosoma cruzi by Dicationic Compounds

Rowland, E. C., Moore-Lai, D., Seed, J. R., Stephens, C. E. & Boykin, D. W., Oct 1 2003, In : Journal of Parasitology. 89, 5, p. 1078-1080 3 p.

Research output: Contribution to journalArticle

10 Scopus citations

The activity of diguanidino and 'reversed' diamidino 2,5-diarylfurans versus Trypanosoma cruzi and Leishmania donovani

Stephens, C. E., Brun, R., Salem, M. M., Werbovetz, K. A., Tanious, F., Wilson, W. D. & Boykin, D. W., Jun 16 2003, In : Bioorganic and Medicinal Chemistry Letters. 13, 12, p. 2065-2069 5 p.

Research output: Contribution to journalArticle

67 Scopus citations
2002

Characterizing the fragmentation of 2,5-bis (4-amidinophenyl)furan-bis-O-methylamidoxime and selected metabolites using ion trap mass spectrometry

Zhou, L., Voyksner, R. D., Thakker, D. R., Stephens, C. E., Anbazhagan, M., Boykin, D. W., Hall, J. E. & Tidwell, R. R., Jun 5 2002, In : Rapid Communications in Mass Spectrometry. 16, 11, p. 1078-1085 8 p.

Research output: Contribution to journalArticle

15 Scopus citations

Distribution of furamidine analogues in tumor cells: Targeting of the nucleus or mitochondria depending on the amidine substitution

Lansiaux, A., Tanious, F., Mishal, Z., Dassonneville, L., Kumar, A., Stephens, C. E., Hu, Q., Wilson, W. D., Boykin, D. W. & Bailly, C., Dec 15 2002, In : Cancer Research. 62, 24, p. 7219-7229 11 p.

Research output: Contribution to journalArticle

63 Scopus citations

Distribution of furamidine analogues in tumor cells: Influence of the number of positive charges

Lansiaux, A., Dassonneville, L., Facompré, M., Kumar, A., Stephens, C. E., Bajic, M., Tanious, F., Wilson, D. W., Boykin, D. W. & Bailly, C., May 9 2002, In : Journal of Medicinal Chemistry. 45, 10, p. 1994-2002 9 p.

Research output: Contribution to journalArticle

64 Scopus citations

Palladium-catalyzed N-arylation of O-methylamidoximes

Anbazhagan, M., Stephens, C. E. & Boykin, D. W., Jun 3 2002, In : Tetrahedron Letters. 43, 23, p. 4221-4224 4 p.

Research output: Contribution to journalArticle

26 Scopus citations

Regioselective cleavage of O-benzyl-N-arylamidoximes: Synthesis of N-aryl amidines and amidoximes

Anbazhagan, M., Boykin, D. W. & Stephens, C. E., Dec 9 2002, In : Tetrahedron Letters. 43, 50, p. 9089-9092 4 p.

Research output: Contribution to journalArticle

12 Scopus citations
2001

Diguanidino and "reversed" diamidino 2,5-diarylfurans as antimicrobial agents

Stephens, C. E., Tanious, F., Kim, S., Wilson, W. D., Schell, W. A., Perfect, J. R., Franzblau, S. G. & Boykin, D. W., May 24 2001, In : Journal of Medicinal Chemistry. 44, 11, p. 1741-1748 8 p.

Research output: Contribution to journalArticle

132 Scopus citations

Evaluation of the influence of compound structure on stacked-dimer formation in the DNA minor groove

Wang, L., Carrasco, C., Kumar, A., Stephens, C. E., Bailly, C., Boykin, D. W. & Wilson, W. D., Feb 27 2001, In : Biochemistry. 40, 8, p. 2511-2521 11 p.

Research output: Contribution to journalArticle

67 Scopus citations

Synthesis and antiviral/antitumor evaluation of 2-amino- and 2-carboxamido-3-arylsulfonylthiophenes and related compounds as a new class of diarylsulfones

Stephens, C. E., Felder, T. M., Sowell, J. W., Andrei, G., Balzarini, J., Snoeck, R. & De Clercq, E., May 1 2001, In : Bioorganic and Medicinal Chemistry. 9, 5, p. 1123-1132 10 p.

Research output: Contribution to journalArticle

55 Scopus citations

Synthesis of deuterium-labelled 2,5-bis(4-amidinophenyl)furan, 2,5-bis[4-(methoxyamidino)phenyl]furan, and 2,7-diamidinocarbazole

Stephens, C. E., Patrick, D. A., Chen, H., Tidwell, R. R. & Boykin, D. W., Mar 19 2001, In : Journal of Labelled Compounds and Radiopharmaceuticals. 44, 3, p. 197-208 12 p.

Research output: Contribution to journalArticle

16 Scopus citations
2000
6 Scopus citations
1999

Palladium catalyzed cross-coupling reactions for the synthesis of 2,5-disubstitutedfurans

Kumar, A., Stephens, C. E. & Boykin, D. W., Jan 1 1999, In : Heterocyclic Communications. 5, 4, p. 301-304 4 p.

Research output: Contribution to journalArticle

19 Scopus citations

Synthesis of methyl 3-amino-4-aryl(or methyl)sulfonyl-2- thiophenecarboxylates from 3-alkoxy-2-aryl(or methyl)-sulfonylacrylonitriles

Stephens, C. E., Price, M. B. & Sowell, J. W., Jan 1 1999, In : Journal of Heterocyclic Chemistry. 36, 3, p. 659-665 7 p.

Research output: Contribution to journalArticle

13 Scopus citations
1998

Synthesis and Cyclization Reactions of 2-Amino-3-[(methoxycarbonyl)methylsulfonyl]pyrroles and Thiophene

Stephens, C. E. & Walter Sowell, J., Jan 1 1998, In : Journal of Heterocyclic Chemistry. 35, 4, p. 933-938 6 p.

Research output: Contribution to journalArticle

4 Scopus citations

Synthesis of Novel Heterocycles from 2-Amino-3-(cyanomethylsulfonyl)thiophene

Stephens, C. E. & Sowell, J. W., Jan 1 1998, In : Journal of Heterocyclic Chemistry. 35, 4, p. 927-931 5 p.

Research output: Contribution to journalArticle

10 Scopus citations
1997

Synthesis of Novel Heterocycles from 2-Amino-3-cyanomethyl-sulfonyl-4,5-dimethylfuran

Stephens, C. E. & Sowell, J. W., Jan 1 1997, In : Journal of Heterocyclic Chemistry. 34, 3, p. 857-860 4 p.

Research output: Contribution to journalArticle

4 Scopus citations
1996

Synthesis of Substituted Pyrrolo[2,3-e][1,3,4]thiadiazine 4,4-Dioxides

Stephens, C. E. & Sowell, J. W., Jan 1 1996, In : Journal of Heterocyclic Chemistry. 33, 6, p. 1615-1617 3 p.

Research output: Contribution to journalArticle

9 Scopus citations