Clive A. Slaughter

Professor

  • 22156 Citations
  • 67 h-Index
1975 …2019
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Research Output 1975 2019

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Article
2017

Article Watch: April 2017

Slaughter, C. A., Apr 1 2017, In : Journal of biomolecular techniques : JBT. 28, 1, p. 56-64 9 p.

Research output: Contribution to journalArticle

Open Access
Telefacsimile

Article Watch: September 2017

Slaughter, C. A., Sep 1 2017, In : Journal of biomolecular techniques : JBT. 28, 3, p. 127-134 8 p.

Research output: Contribution to journalArticle

Open Access
Telefacsimile
2 Citations (Scopus)

Teaching Biochemistry and Genetics to Students of Medicine, Pharmacy, and Dentistry: 6 th International Conference of the Association of Biochemistry Educators (ABE) Clearwater Beach, FL, USA, May 7-11, 2017

Niederhoffer, E. C., Cline, S. D., Osheroff, N., Simmons, J. M., Diekman, A. B., Franklin, D. S., Abali, E. E., Bateman, R. C., Fontes, J. D., Lindsley, J. E., Pearson, D., Rubenstein, P. A., Slaughter, C. A., Bernstein, J. A., Hyland, K. M., Park, V. M., Sobering, A. K., Weiler, T. A. & Dasgupta, S., Dec 1 2017, In : Medical Science Educator. 27, 4, p. 855-859 5 p.

Research output: Contribution to journalArticle

Pharmacy Students
biochemistry
dentistry
Dentistry
Biochemistry
2015

Article watch: September 2015

Slaughter, C. A., Sep 1 2015, In : Journal of Biomolecular Techniques. 26, 3, p. 113-117 5 p.

Research output: Contribution to journalArticle

Article watch: December 2015

Slaughter, C. A., Dec 1 2015, In : Journal of Biomolecular Techniques. 26, 4, p. 150-156 7 p.

Research output: Contribution to journalArticle

Teaching Biochemistry to Students of Medicine, Pharmacy and Dentistry: 5th International Conference of the Association of Biochemistry Course Directors (ABCD) Santa Fe, NM, USA, May 3–7, 2015

Osheroff, N., Niederhoffer, E. C., Sabina, R. L., Cline, S. D., Wimmer, M. J., Franklin, D. S., Diekman, A. B., Hogg, T., Kearney, K. R., King, S. C., Pearson, D., Slaughter, C. A. & Thompson, K., Dec 1 2015, In : Medical Science Educator. 25, 4, p. 473-477 5 p.

Research output: Contribution to journalArticle

Osteopathic Medicine
Pharmacy Education
Pharmacy Students
biochemistry
dentistry
2014

Article watch: September 2014

Slaughter, C. A., Sep 1 2014, In : Journal of Biomolecular Techniques. 25, 3, p. 87-91 5 p.

Research output: Contribution to journalArticle

Telefacsimile
2012

Article watch, July 2011

Slaughter, C., Jul 1 2012, In : Journal of Biomolecular Techniques. 22, 2, p. 86-89 4 p.

Research output: Contribution to journalArticle

2011
63 Citations (Scopus)

A20-binding inhibitor of NF-κB (ABIN1) controls Toll-like receptor-mediated CCAAT/enhancer-binding protein β activation and protects from inflammatory disease

Zhou, J., Wu, R., High, A. A., Slaughter, C. A., Finkelstein, D., Rehg, J. E., Redecke, V. & Häcker, H., Nov 1 2011, In : Proceedings of the National Academy of Sciences of the United States of America. 108, 44, p. E998-E1006

Research output: Contribution to journalArticle

CCAAT-Enhancer-Binding Proteins
Toll-Like Receptors
Nitric Oxide Synthase Type II
Inflammation
Anti-Inflammatory Agents

Article watch, April 2011

Slaughter, C., Apr 1 2011, In : Journal of Biomolecular Techniques. 22, 1, p. 45-49 5 p.

Research output: Contribution to journalArticle

Article watch, September 2011

Slaughter, C. A., Sep 1 2011, In : Journal of Biomolecular Techniques. 22, 3, p. 119-121 3 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Bub1-mediated adaptation of the spindle checkpoint

Goto, G. H., Mishra, A., Abdulle, R., Slaughter, C. A. & Kitagawa, K., Feb 15 2011, In : PLoS Genetics. 7, 1, e1001282.

Research output: Contribution to journalArticle

Anaphase
anaphase
chromosome
Microtubules
microtubules
2009
44 Citations (Scopus)

Large-scale analysis of thermostable, mammalian proteins provides insights into the intrinsically disordered proteome

Galea, C. A., High, A. A., Obenauer, J. C., Mlshra, A., Park, C. G., Punta, M., Schlesslnger, A., Jing, M., Rost, B., Slaughter, C. A. & Kriwacki, R. W., Jan 1 2009, In : Journal of Proteome Research. 8, 1, p. 211-226 16 p.

Research output: Contribution to journalArticle

Proteome
Proteins
Cells
Fibroblasts
Genes
2008
111 Citations (Scopus)

Differential roles of the COOH termini of AAA subunits of PA700 (19 S regulator) in asymmetric assembly and Activation of the 26 S proteasome

Gillette, T. G., Kumar, B., Thompson, D., Slaughter, C. A. & DeMartino, G. N., Nov 14 2008, In : Journal of Biological Chemistry. 283, 46, p. 31813-31822 10 p.

Research output: Contribution to journalArticle

Proteasome Endopeptidase Complex
Chemical activation
Peptides
Hydrolysis
Substrates
2007
31 Citations (Scopus)
carbovir
Zidovudine
Solid Phase Extraction
Metabolites
Anions
2006
34 Citations (Scopus)

Crystal structure of a glycosylated Fab from an IgM cryoglobulin with properties of a natural proteolytic antibody

Ramsland, P. A., Terzyan, S. S., Cloud, G., Bourne, C. R., Farrugia, W., Tribbick, G., Geysen, H. M., Moomaw, C. R., Slaughter, C. A. & Edmundson, A. B., May 1 2006, In : Biochemical Journal. 395, 3, p. 473-481 9 p.

Research output: Contribution to journalArticle

Cryoglobulins
Immunoglobulin M
Crystal structure
Antigens
Antibodies
47 Citations (Scopus)

Proteomic studies of the intrinsically unstructured mammalian proteome

Galea, C. A., Pagala, V. R., Obenauer, J. C., Park, C. G., Slaughter, C. A. & Kriwacki, R. W., Oct 1 2006, In : Journal of Proteome Research. 5, 10, p. 2839-2848 10 p.

Research output: Contribution to journalArticle

Intrinsically Disordered Proteins
Proteome
Proteomics
Cell signaling
Fibroblasts
12 Citations (Scopus)

The influence of phosphorylation on the activity and structure of the neuronal IQ motif protein, PEP-19

Dickerson, J. B., Morgan, M. A., Mishra, A., Slaughter, C. A., Morgan, J. I. & Zheng, J., May 30 2006, In : Brain Research. 1092, 1, p. 16-27 12 p.

Research output: Contribution to journalArticle

Amino Acid Motifs
Calmodulin
Phosphorylation
Serine
camstatin
2005
6 Citations (Scopus)

A bright but demanding future for core facilities

Slaughter, C. A., Jun 1 2005, In : Journal of Biomolecular Techniques. 16, 2, p. 167-169 3 p.

Research output: Contribution to journalArticle

Systems Biology
Biomedical Research
Research Personnel
26 Citations (Scopus)

Activation of pre-mRNA splicing by human RNPS1 is regulated by CK2 phosphorylation

Trembley, J. H., Tatsumi, S., Sakashita, E., Loyer, P., Slaughter, C. A., Suzuki, H., Endo, H., Kidd, V. J. & Mayeda, A., Feb 1 2005, In : Molecular and Cellular Biology. 25, 4, p. 1446-1457 12 p.

Research output: Contribution to journalArticle

RNA Precursors
Phosphorylation
Serine
Exons
Protein Splicing
113 Citations (Scopus)

Phosphorylation of FADD at serine 194 by CKIα regulates its nonapoptotic activities

Alappat, E. C., Feig, C., Boyerinas, B., Volkland, J., Samuels, M., Murmann, A. E., Thorburn, A., Kidd, V. J., Slaughter, C. A., Osborn, S. L., Winoto, A., Tang, W. J. & Peter, M. E., Aug 5 2005, In : Molecular Cell. 19, 3, p. 321-332 12 p.

Research output: Contribution to journalArticle

Casein Kinase I
Serine
Phosphorylation
Mitosis
Spindle Poles
14 Citations (Scopus)

T cell epitope "hotspots" on the HIV type 1 gp120 envelope protein overlap with tryptic fragments displayed by mass spectrometry

Brown, S. A., Lockey, T. D., Slaughter, C., Slobod, K. S., Surman, S., Zirkel, A., Mishra, A., Pagala, V. R., Coleclough, C., Doherty, P. C. & Hurwitz, J. L., Feb 1 2005, In : AIDS Research and Human Retroviruses. 21, 2, p. 165-170 6 p.

Research output: Contribution to journalArticle

T-Lymphocyte Epitopes
Mass Spectrometry
Immunodominant Epitopes
Peptides
T-Lymphocytes
2004
62 Citations (Scopus)

A Novel CRM1-mediated Nuclear Export Signal Governs Nuclear Accumulation of Glyceraldehyde-3-phosphate Dehydrogenase following Genotoxic Stress

Brown, V. M., Krynetski, E. Y., Krynetskaia, N. F., Grieger, D., Mukatira, S. T., Murti, K. G., Slaughter, C. A., Park, H. W. & Evans, W. E., Feb 13 2004, In : Journal of Biological Chemistry. 279, 7, p. 5984-5992 9 p.

Research output: Contribution to journalArticle

Nuclear Export Signals
Glyceraldehyde-3-Phosphate Dehydrogenases
DNA Damage
U5 Small Nuclear Ribonucleoproteins
rev Gene Products
55 Citations (Scopus)

Tyrosine phosphorylated Disabled 1 recruits Crk family adapter proteins

Huang, Y., Magdaleno, S., Hopkins, R., Slaughter, C. A., Curran, T. & Keshvara, L., May 21 2004, In : Biochemical and Biophysical Research Communications. 318, 1, p. 204-212 9 p.

Research output: Contribution to journalArticle

Tyrosine
Phosphorylation
Brain
Proteins
Phosphotyrosine
2003
50 Citations (Scopus)

Casein kinase 2 interacts with cyclin-dependent kinase 11 (CDK11) in vivo and phosphorylates both the rna polymerase II carboxyl-terminal domain and CDk11 in vitro

Trembley, J. H., Hu, D., Slaughter, C. A., Lahti, J. M. & Kidd, V. J., Jan 24 2003, In : Journal of Biological Chemistry. 278, 4, p. 2265-2270 6 p.

Research output: Contribution to journalArticle

Casein Kinase II
Cyclin-Dependent Kinases
RNA Polymerase II
Transcription
Protein Kinases
2002
40 Citations (Scopus)

Binding of JNK/SAPK to MEKK1 is regulated by phosphorylation

Gallagher, E. D., Xu, S., Moomaw, C., Slaughter, C. A. & Cobb, M. H., Nov 29 2002, In : Journal of Biological Chemistry. 277, 48, p. 45785-45792 8 p.

Research output: Contribution to journalArticle

Phosphorylation
JNK Mitogen-Activated Protein Kinases
Heat-Shock Proteins
Protein Kinases
Serine
107 Citations (Scopus)

Identification of a multifunctional binding site on Ubc9p required for Smt3p conjugation

Bencsath, K. P., Podgorski, M. S., Pagala, V. R., Slaughter, C. A. & Schulman, B. A., Dec 6 2002, In : Journal of Biological Chemistry. 277, 49, p. 47938-47945 8 p.

Research output: Contribution to journalArticle

Ubiquitins
Binding Sites
Adenosine Triphosphate
Enzymes
Ubiquitin
62 Citations (Scopus)

PITSLRE p110 protein kinases associate with transcription complexes and affect their activity

Trembley, J. H., Hu, D., Hsu, L. C., Yeung, C. Y., Slaughter, C., Lahti, J. M. & Kidd, V. J., Jan 25 2002, In : Journal of Biological Chemistry. 277, 4, p. 2589-2596 8 p.

Research output: Contribution to journalArticle

Transcription
Protein Kinases
Phosphotransferases
RNA Polymerase II
RNA
140 Citations (Scopus)

Sustained high-level expression of human factor IX (hFIX) after liver-targeted delivery of recombinant adeno-associated virus encoding the hFIX gene in rhesus macaques

Nathwani, A. C., Davidoff, A. M., Hanawa, H., Hu, Y., Hoffer, F. A., Nikanorov, A., Slaughter, C., Ng, C. Y. C., Zhou, J., Lozier, J. N., Mandrell, T. D., Vanin, E. F. & Nienhuis, A. W., Sep 1 2002, In : Blood. 100, 5, p. 1662-1669 8 p.

Research output: Contribution to journalArticle

Dependovirus
Factor IX
Human engineering
Macaca mulatta
Viruses
26 Citations (Scopus)

Three-dimensional structure of an immunoglobulin light-chain dimer with amyloidogenic properties

Bourne, P. C., Ramsland, P. A., Shan, L., Fan, Z. C., DeWitt, C. R., Shultz, B. B., Terzyan, S. S., Moomaw, C. R., Slaughter, C. A., Guddat, L. W. & Edmundson, A. B., Jan 1 2002, In : Acta Crystallographica Section D: Biological Crystallography. 58, 5, p. 815-823 9 p.

Research output: Contribution to journalArticle

Immunoglobulin Light Chains
Oceans and Seas
Bence Jones Protein
Amyloidosis
Amyloidogenic Proteins
2001
47 Citations (Scopus)

Endothelin-1 Stimulates Leptin Production in Adipocytes

Xiong, Y., Tanaka, H., Richardson, J. A., Williams, S. C., Slaughter, C. A., Nakamura, M., Chen, J. L. & Yanagisawa, M., Jul 27 2001, In : Journal of Biological Chemistry. 276, 30, p. 28471-28477 7 p.

Research output: Contribution to journalArticle

Endothelin-1
Leptin
Adipocytes
Northern Blotting
White Adipocytes
2000
1315 Citations (Scopus)

Activation of the Iκb kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain

Deng, L., Wang, C., Spencer, E., Yang, L., Braun, A., You, J., Slaughter, C., Pickart, C. & Chen, Z. J., Oct 13 2000, In : Cell. 103, 2, p. 351-361 11 p.

Research output: Contribution to journalArticle

TNF Receptor-Associated Factor 6
Polyubiquitin
Ubiquitin-Conjugating Enzymes
Phosphotransferases
Chemical activation
16 Citations (Scopus)

An unusual human IgM antibody with a protruding HCDR3 and high avidity for its peptide ligands

Ramsland, P. A., Shan, L., Moomaw, C. R., Slaughter, C. A., Fan, Z. C., Guddat, L. W. & Edmundson, A. B., Oct 3 2000, In : Molecular Immunology. 37, 6, p. 295-310 16 p.

Research output: Contribution to journalArticle

Complementarity Determining Regions
Immunoglobulin M
Ligands
Peptides
Antibodies
30 Citations (Scopus)

Carica papaya glutamine cyclotransferase belongs to a novel plant enzyme subfamily: Cloning and characterization of the recombinant enzyme

Dahl, S. W., Slaughter, C., Lauritzen, C., Bateman, R. C., Connerton, I. & Pedersen, J., Jan 1 2000, In : Protein Expression and Purification. 20, 1, p. 27-36 10 p.

Research output: Contribution to journalArticle

glutaminyl-peptide cyclotransferase
Carica
Protein Sequence Analysis
Protein Sorting Signals
Organism Cloning
91 Citations (Scopus)

cDNA cloning, expression, and functional characterization of PI31, a proline-rich inhibitor of the proteasome

McCutchen-Maloney, S. L., Matsuda, K., Shimbara, N., Binns, D. D., Tanaka, K., Slaughter, C. A. & DeMartino, G. N., Jun 16 2000, In : Journal of Biological Chemistry. 275, 24, p. 18557-18565 9 p.

Research output: Contribution to journalArticle

Proteasome Inhibitors
Cloning
Proteasome Endopeptidase Complex
Proline
Organism Cloning
26 Citations (Scopus)

Evaluation of an isogenic major outer membrane protein-deficient mutant in the human model of Haemophilus ducreyi infection

Throm, R. E., Al-Tawfiq, J. A., Fortney, K. R., Katz, B. P., Hood, A. F., Slaughter, C. A., Hansen, E. J. & Spinola, S. M., May 1 2000, In : Infection and Immunity. 68, 5, p. 2602-2607 6 p.

Research output: Contribution to journalArticle

Haemophilus ducreyi
Haemophilus Infections
Membrane Proteins
Open Reading Frames
Porins
89 Citations (Scopus)

Identification and functional expression of four isoforms of ATPase II, the putative aminophospholipid translocase: Effect of isoform variation on the ATPase activity and phospholipid specificity

Ding, J., Wu, Z., Crider, B. P., Ma, Y., Li, X., Slaughter, C. A., Gong, L. & Xie, X. S., Jul 28 2000, In : Journal of Biological Chemistry. 275, 30, p. 23378-23386 9 p.

Research output: Contribution to journalArticle

Phospholipid Transfer Proteins
Adenosine Triphosphatases
Phospholipids
Protein Isoforms
Phosphatidylserines
155 Citations (Scopus)

In organello formaldehyde crosslinking of proteins to mtDNA: Identification of bifunctional proteins

Kaufman, B. A., Newman, S. M., Hallberg, R. L., Slaughter, C. A., Perlman, P. S. & Butow, R. A., Jul 5 2000, In : Proceedings of the National Academy of Sciences of the United States of America. 97, 14, p. 7772-7777 6 p.

Research output: Contribution to journalArticle

Mitochondrial DNA
Formaldehyde
Proteins
DNA
High Mobility Group Proteins
36 Citations (Scopus)

Proteolytic cleavage of the Fe - S subunit hinge region of Rhodobacter capsulatus bc1 complex: Effects of inhibitors and mutations

Valkova-Valchanova, M., Darrouzet, E., Moomaw, C. R., Slaughter, C. A. & Daldal, F., Dec 19 2000, In : Biochemistry. 39, 50, p. 15484-15492 9 p.

Research output: Contribution to journalArticle

Rhodobacter capsulatus
Hinges
Proteolysis
Mutation
Conformations
74 Citations (Scopus)

The 21- and 23-kD forms of TCRζ are generated by specific ITAM phosphorylations

Van Oers, N. S. C., Tohlen, B., Malissen, B., Moomaw, C. R., Afendis, S. & Slaughter, C. A., Oct 2000, In : Nature Immunology. 1, 4, p. 322-328 7 p.

Research output: Contribution to journalArticle

Immunoreceptor Tyrosine-Based Activation Motif
T-Cell Antigen Receptor
Phosphorylation
Tyrosine
src Homology Domains
1999
87 Citations (Scopus)

Characterization of the Moraxella catarrhalis uspA1 and uspA2 genes and their encoded products

Cope, L. D., Lafontaine, E. R., Slaughter, C. A., Hasemann, C. A., Aebi, C., Henderson, F. W., McCracken, G. H. & Hansen, E. J., Jul 1 1999, In : Journal of Bacteriology. 181, 13, p. 4026-4034 9 p.

Research output: Contribution to journalArticle

Moraxella (Branhamella) catarrhalis
Genes
Amino Acid Motifs
Proteins
Sequence Analysis
32 Citations (Scopus)

Interaction of the N-terminus of chicken skeletal essential light chain 1 with F-actin

Andreev, O. A., Saraswat, L. D., Lowey, S., Slaughter, C. & Borejdo, J., Feb 23 1999, In : Biochemistry. 38, 8, p. 2480-2485 6 p.

Research output: Contribution to journalArticle

alanylproline
Actins
Chickens
Lysine
Light

Novel HY peptide antigens presented by HLA-B27.

Taurog, J. D., Hammer, R. E., Moomaw, C. R., Slaughter, C. A., Roopenian, D. C., Zuberi, A. R., Gaskell, S. J., Bordoli, R. S., Colbert, R. A., Butcher, G. W. & Leong, L. Y., Nov 15 1999, In : Journal of Immunology. 163, 10

Research output: Contribution to journalArticle

H-Y Antigen
HLA-B27 Antigen
Peptides
85 Citations (Scopus)

Palmitoylation of a conserved cysteine in the regulator of G protein signaling (RGS) domain modulates the GTPase-activating activity of RGS4 and RGS10

Tu, Y., Popov, S., Slaughter, C. & Ross, E. M., Dec 31 1999, In : Journal of Biological Chemistry. 274, 53, p. 38260-38267 8 p.

Research output: Contribution to journalArticle

GTP-Binding Protein Regulators
Lipoylation
GTPase-Activating Proteins
GTP Phosphohydrolases
GTP-Binding Proteins
57 Citations (Scopus)

Secreted Site-1 protease cleaves peptides corresponding to luminal loop of sterol regulatory element-binding proteins

Cheng, D., Espenshade, P. J., Slaughter, C. A., Jaen, J. C., Brown, M. S. & Goldstein, J. L., Aug 6 1999, In : Journal of Biological Chemistry. 274, 32, p. 22805-22812 8 p.

Research output: Contribution to journalArticle

Sterol Regulatory Element Binding Proteins
Peptides
Sterol Regulatory Element Binding Protein 2
Peptide Hydrolases
Biosynthesis
1998
2860 Citations (Scopus)

Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors

Luo, X., Budihardjo, I., Zou, H., Slaughter, C. & Wang, X., Aug 21 1998, In : Cell. 94, 4, p. 481-490 10 p.

Research output: Contribution to journalArticle

Death Domain Receptors
Mitochondria
Cell Surface Receptors
Cytochromes c
Cell Death
40 Citations (Scopus)

cDNA cloning and characterization of a human proteasomal modulator subunit, p27 (PSMD9)

Watanabe, T. K., Saito, A., Suzuki, M., Fujiwara, T., Takahashi, E. I., Slaughter, C. A., DeMartino, G. N., Hendil, K. B., Chung, C. H., Tanahashi, N. & Tanaka, K., Jun 1 1998, In : Genomics. 50, 2, p. 241-250 10 p.

Research output: Contribution to journalArticle

Organism Cloning
Complementary DNA
Yeasts
Chromosomes, Human, Pair 12
Proteins
72 Citations (Scopus)

cDNA cloning and functional analysis of p28 (Nas6p) and p40.5 (Nas7p), two novel regulatory subunits of the 26S proteasome

Hori, T., Kato, S., Saeki, M., DeMartino, G. N., Slaughter, C. A., Takeuchi, J., Toh-e, A. & Tanaka, K., Aug 17 1998, In : Gene. 216, 1, p. 113-122 10 p.

Research output: Contribution to journalArticle

Organism Cloning
Complementary DNA
Yeasts
Ankyrin Repeat
Fungal Proteins
43 Citations (Scopus)

Formation of proteasome-PA700 complexes directly correlates with activation of peptidase activity

Adams, G. M., Crotchett, B., Slaughter, C. A., DeMartino, G. N. & Gogol, E. P., Sep 15 1998, In : Biochemistry. 37, 37, p. 12927-12932 6 p.

Research output: Contribution to journalArticle

Proteasome Endopeptidase Complex
Peptide Hydrolases
Chemical activation
Modulators
PA700 proteasome activator
38 Citations (Scopus)

Mapping of a protective epitope of the CopB outer membrane protein of Moraxella catarrhalis

Aebi, C., Cope, L. D., Latimer, J. L., Thomas, S. E., Slaughter, C. A., McCracken, G. H. & Hansen, E. J., Feb 25 1998, In : Infection and Immunity. 66, 2, p. 540-548 9 p.

Research output: Contribution to journalArticle

Moraxella (Branhamella) catarrhalis
Epitopes
Membrane Proteins
Monoclonal Antibodies
Proteins