Daitoku Sakamuro

Research output

Research output per year 1988 2019

• 2276 Citations
• 21 h-Index
• 32 Article
• 3 Review article
• 1 Comment/debate

Research output per year

Research output per year

Search results

• 2019

  Loss of the tumor suppressor BIN1 enables ATM Ser/Thr kinase activation by the nuclear protein E2F1 and renders cancer cells resistant to cisplatin

  Folk, W. P., Kumari, A., Iwasaki, T., Pyndiah, S., Johnson, J. C., Cassimere, E. K., Abdulovic-Cui, A. L. & Sakamuro, D., Apr 5 2019, In: Journal of Biological Chemistry. 294, 14, p. 5700-5719 20 p.

  Research output: Contribution to journal › Article › peer-review

  • Ataxia Telangiectasia
  • Nuclear Proteins
  • Tumors
  • Cells
  • Cisplatin
  5 Scopus citations
• 2018

  Endocrine disruptor exposure during development increases incidence of uterine fibroids by altering DNA repair in myometrial stem cells

  Prusinski Fernung, L., Yang, Q., Sakamuro, D., Kumari, A., Mas, A. & Al-Hendy, A., Oct 1 2018, In: Biology of reproduction. 99, 4, p. 735-748 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Endocrine Disruptors
  • Leiomyoma
  • DNA Repair
  • Stem Cells
  • Incidence
  8 Scopus citations
• 2015

  Regulation of E2F1-induced apoptosis by poly(ADP-ribosyl)ation

  Kumari, A., Iwasaki, T., Pyndiah, S., Cassimere, E. K., Palani, C. D. & Sakamuro, D., Feb 1 2015, In: Cell Death and Differentiation. 22, 2, p. 311-322 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Poly ADP Ribosylation
  • Poly (ADP-Ribose) Polymerase-1
  • Apoptosis
  • Starvation
  • Serum
  24 Scopus citations

• Restoration of tumor suppressor functions by small-molecule inhibitors

  Pyndiah, S. & Sakamuro, D., Jul 3 2015, In: Molecular and Cellular Oncology. 2, 3, e991225.

  Research output: Contribution to journal › Article › peer-review

  • Tumor Suppressor Proteins
  • Neoplasms
  • Therapeutics

• To die, or not to die: E2F1 never decides by itself during serum starvation

  Sakamuro, D., Folk, W. P. & Kumari, A., Apr 3 2015, In: Molecular and Cellular Oncology. 2, 2, e981447.

  Research output: Contribution to journal › Article › peer-review

  • Starvation
  • Apoptosis
  • DNA Damage
  • Poly ADP Ribosylation
  • Serum
  2 Scopus citations
• 2013

  Un trio de choc pour pallier la chimiorésistance des cancers c-MYC, PARP1, BIN1

  Pyndiah, S. & Sakamuro, D., Feb 2013, In: Medecine/Sciences. 29, 2, p. 133-135 3 p.

  Research output: Contribution to journal › Article › peer-review
  5 Scopus citations
• 2011

  c-MYC suppresses BIN1 to release poly(ADP-ribose) polymerase 1: A mechanism by which cancer cells acquire cisplatin resistance

  Pyndiah, S., Tanida, S., Ahmed, K. M., Cassimere, E. K., Choe, C. & Sakamuro, D., Mar 29 2011, In: Science Signaling. 4, 166, ra19.

  Research output: Contribution to journal › Article › peer-review

  • Poly (ADP-Ribose) Polymerase-1
  • Cells
  • Cisplatin
  • Genes
  • Catalyst activity
  60 Scopus citations

• Identification of a novel effector domain of BIN1 for cancer suppression

  Lundgaard, G. L., Daniels, N. E., Pyndiah, S., Cassimere, E. K., Ahmed, K. M., Rodrigue, A., Kihara, D., Post, C. B. & Sakamuro, D., Oct 2011, In: Journal of cellular biochemistry. 112, 10, p. 2992-3001 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Peptides
  • Trypsin
  • Neoplasms
  • Tumor Suppressor Proteins
  • Mass spectrometry
  9 Scopus citations
• 2009

  The c-MYC-interacting proapoptotic tumor suppressor BIN1 is a transcriptional target for E2F1 in response to DNA damage

  Cassimere, E. K., Pyndiah, S. & Sakamuro, D., 2009, In: Cell Death and Differentiation. 16, 12, p. 1641-1653 13 p.

  Research output: Contribution to journal › Article › peer-review

  • DNA Damage
  • Etoposide
  • Apoptosis
  • Tumor Protein p73
  • E2F1 Transcription Factor
  25 Scopus citations
• 2008

  Adenovirus E1A oncoprotein liberates c-Myc activity to promote cell proliferation through abating Bin1 expression via an Rb/E2F1-dependent mechanism

  Kinney, E. L., Tanida, S., Rodrigue, A. A., Johnson, J. K., Tompkins, V. S. & Sakamuro, D., Sep 2008, In: Journal of Cellular Physiology. 216, 3, p. 621-631 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Cell proliferation
  • Fibroblasts
  • Oncogene Proteins
  • Adenoviridae
  • Small Interfering RNA
  15 Scopus citations
• 2007

  Bin1 attenuation in breast cancer is correlated to nodal metastasis and reduced survival

  Ghaneie, A., Zemba-Palko, V., Itoh, H., Itoh, K., Sakamuro, D., Nakamura, S., Soler, A. P. & Prendergast, G. C., Feb 2007, In: Cancer Biology and Therapy. 6, 2, p. 192-194 3 p.

  Research output: Contribution to journal › Article › peer-review

  • Breast Neoplasms
  • Neoplasm Metastasis
  • Survival
  • Neoplastic Cell Transformation
  • Modifier Genes
  21 Scopus citations

• Induction of Fas (CD95/APO-1) ligand is essential for p53-dependent apoptosis in an in vitro renal carcinoma model system

  Okazaki, T. & Sakamuro, D., Sep 2007, In: Journal of Cancer Research and Clinical Oncology. 133, 9, p. 581-588 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Ligands
  • Carcinoma
  • Apoptosis
  • fas Receptor
  • Kidney
  7 Scopus citations
• 2001

  Bin1 mediates apoptosis by c-Myc in transformed primary cells

  DuHadaway, J. B., Sakamuro, D., Ewert, D. L. & Prendergast, G. C., Apr 1 2001, In: Cancer Research. 61, 7, p. 3151-3156 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Capital Punishment
  • Cell Death
  • Tumor Suppressor Proteins
  • Apoptosis
  • Carrier Proteins
  66 Scopus citations
• 2000

  Losses of the tumor suppressor BIN1 in breast carcinoma are frequent and reflect deficits in programmed cell death capacity

  Ge, K., Duhadaway, J., Sakamuro, D., Wechsler-Reya, R., Reynolds, C. & Prendergast, G. C., 2000, In: International Journal of Cancer. 85, 3, p. 376-383 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Cell Death
  • Breast Neoplasms
  • Estrogen Receptors
  • Breast
  • Neoplasms
  77 Scopus citations

• Loss of heterozygosity and tumor suppressor activity of BIN1 in prostate carcinoma

  Ge, K., Minhas, F., Duhadaway, J., Mao, N. C., Wilson, D., Buccafusca, R., Sakamuro, D., Nelson, P., Malkowicz, S. B., Tomaszewski, J. & Prendergast, G. C., Apr 12 2000, In: International Journal of Cancer. 86, 2, p. 155-161 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Loss of Heterozygosity
  • Prostate
  • Carcinoma
  • Prostatic Neoplasms
  • Neoplasms
  78 Scopus citations
• 1999

  Bin1 functionally interacts with Myc and inhibits cell proliferation via multiple mechanisms

  Elliott, K., Sakamuro, D., Basu, A., Du, W., Wunner, W., Staller, P., Gaubatz, S., Zhang, H., Prochownik, E., Eilers, M. & Prendergast, G. C., Jun 17 1999, In: Oncogene. 18, 24, p. 3564-3573 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Cell Proliferation
  • Ornithine Decarboxylase
  • Growth
  • Transcriptional Activation
  • myc Genes
  94 Scopus citations
• 1997

  Farnesyl transferase inhibitors induce apoptosis of Ras-transformed cells denied substratum attachment

  Lebowitz, P. F., Sakamuro, D. & Prendergast, G. C., 1997, In: Cancer Research. 57, 4, p. 708-713 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Transferases
  • Apoptosis
  • L 739749
  • Ectopic Gene Expression
  • Antineoplastic Agents
  176 Scopus citations

• Structural analysis of the human BIN1 gene: Evidence for tissue-specific transcriptional regulation and alternate RNA splicing

  Wechsler-Reya, R., Sakamuro, D., Zhang, J., Duhadaway, J. & Prendergast, G. C., Dec 12 1997, In: Journal of Biological Chemistry. 272, 50, p. 31453-31458 6 p.

  Research output: Contribution to journal › Article › peer-review

  • amphiphysin
  • RNA Splicing
  • Alternative Splicing
  • Structural analysis
  • Genes
  113 Scopus citations

• The polyproline region of p53 is required to activate apoptosis but not growth arrest

  Sakamuro, D., Sabbatini, P., White, E. & Prendergast, G. C., 1997, In: Oncogene. 15, 8, p. 887-898 12 p.

  Research output: Contribution to journal › Article › peer-review

  • polyproline
  • Apoptosis
  • Growth
  • Transcriptional Activation
  • DNA
  239 Scopus citations
• 1996

  BIN1 is a novel MYC-interacting protein with features of a tumour suppressor

  Sakamuro, D., Elliott, K. J., Wechsler-Reya, R. & Prendergast, G. C., Sep 1996, In: Nature Genetics. 14, 1, p. 69-77 9 p.

  Research output: Contribution to journal › Article › peer-review

  • amphiphysin
  • Breast Neoplasms
  • Oncogene Proteins
  • Ectopic Gene Expression
  • Proteins
  293 Scopus citations

• Detection of a unique γ-glutamyl transpeptidase messenger RNA species closely related to the development of hepatocellular carcinoma in humans: A new candidate for early diagnosis of hepatocellular carcinoma

  Tsutsumi, M., Sakamuro, D., Takada, A., Zang, S. C., Furukawa, T. & Taniguchi, N., 1996, In: Hepatology. 23, 5, p. 1093-1097 5 p.

  Research output: Contribution to journal › Article › peer-review

  • gamma-Glutamyltransferase
  • Early Diagnosis
  • Hepatocellular Carcinoma
  • Messenger RNA
  • RNA
  47 Scopus citations

• The Bin1 gene localizes to human chromosome 2q14 by PCR analysis of somatic cell hybrids and fluorescence in situ hybridization

  Negorev, D., Riethman, H., Wechsler-Reya, R., Sakamuro, D., Prendergast, G. C. & Simon, D., Apr 15 1996, In: Genomics. 33, 2, p. 329-331 3 p.

  Research output: Contribution to journal › Article › peer-review
  24 Scopus citations
• 1995

  c-Myc induces apoptosis in epithelial cells by both p53-dependent and p53-independent mechanisms

  Sakamuro, D., Eviner, V., Elliott, K. J., Showe, L., White, E. & Prendergast, G. C., Dec 7 1995, In: Oncogene. 11, 11, p. 2410-2418 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Epithelial Cells
  • Apoptosis
  • Temperature
  • Cell Death
  • G1 Phase Cell Cycle Checkpoints
  155 Scopus citations

• Hepatitis C virus nonstructural protein NS3 transforms NIH 3T3 cells

  Sakamuro, D., Furukawa, T. & Takegami, T., Jan 1 1995, In: Journal of Virology. 69, 6, p. 3893-3896 4 p.

  Research output: Contribution to journal › Article › peer-review

  • hepatitis C virus NS3 protein
  • Hepatitis C virus
  • NIH 3T3 Cells
  • Hepacivirus
  • Complementary DNA
  277 Scopus citations

• Japanese encephalitis virus nonstructural protein NS3 has RNA binding and ATPase activities

  Takegami, T., Sakamuro, D. & Furukawa, T., Jan 1 1995, In: Virus Genes. 9, 2, p. 105-112 8 p.

  Research output: Contribution to journal › Article › peer-review

  • flavivirus NS3 protein
  • Japanese Encephalitis Virus
  • Adenosine Triphosphatases
  • RNA
  • Proteins
  39 Scopus citations
• 1994

  Detection of human cytomegalovirus genome in uterus tissue

  Furukawa, T., Jisaki, F., Sakamuro, D., Takegami, T. & Murayama, T., Sep 1 1994, In: Archives of Virology. 135, 3-4, p. 265-277 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Human Genome
  • Cytomegalovirus
  • Uterus
  • Cytomegalovirus Infections
  • Myoma
  23 Scopus citations

• Different antibody response to a neutralizing epitope of human cytomegalovirus glycoprotein B among seropositive individuals

  Ayata, M., Sugano, T., Murayama, T., Sakamuro, D., Takegami, T., Matsumoto, YI. I. & Furukawa, T., Aug 1994, In: Journal of Medical Virology. 43, 4, p. 386-392 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Simplexvirus glycoprotein B
  • Antibody Formation
  • Epitopes
  • Viral Fusion Proteins
  • Monoclonal Antibodies
  11 Scopus citations

• Elevated cytokine levels in synovial fluid of rheumatoid arthritis correlates with the presence of cytomegalovirus genome

  Murayama, T., Tsuchiya, N., Jisaki, F., Ozaki, M., Sakamuro, D., Hirai, K., Shimizu, S., Ito, K., Matsushima, K. & Furukawa, T., 1994, In: Autoimmunity. 17, 4, p. 333-337 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Synovial Fluid
  • Cytomegalovirus
  • Rheumatoid Arthritis
  • Genome
  • Cytokines
  12 Scopus citations
• 1992

  Cytomegalovirus genomes demonstrates by polymerase chain reaction in synovial fluid from rheumatoid arthritis patients

  Murayama, T., Jisaki, F., Ayata, M., Sakamuro, D., Hironaka, T., Hirai, K., Tsuchiya, N., Ito, K. & Furukawa, T., Jan 1 1992, In: Clinical and Experimental Rheumatology. 10, 2, p. 161-164 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Synovial Fluid
  • Cytomegalovirus
  • Rheumatoid Arthritis
  • Genome
  • Polymerase Chain Reaction
  21 Scopus citations
• 1990

  Synthesis of human gamma-glutamyl transpeptidase (GGT) during the fetal development of liver

  Shiozawa, M., Hiraoka, Y., Yasuda, K., Imamura, T., Sakamuro, D., Taniguchi, N., Yamazoe, M. & Yoshikawa, H., Mar 15 1990, In: Gene. 87, 2, p. 299-303 5 p.

  Research output: Contribution to journal › Article › peer-review

  • gamma-Glutamyltransferase
  • Fetal Development
  • Liver
  • Messenger RNA
  • Bile Canaliculi
  10 Scopus citations
• 1988

  Polymorphonuclear cell factor found in patients with rheumatoid arthritis

  Wakitani, S., Sakamuro, D., Ochi, T., Owaki, H., Fujimoto, M. & Ono, K., Jan 1 1988, In: Biomedical Research. 9, 5, p. 395-399 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Collagenases
  • Bone
  • Blood
  • Rheumatoid Arthritis
  • Fluids
  2 Scopus citations

• The primary structure of human gamma-glutamyl transpeptidase

  Daitoku, S., Mitsuyoshi, Y., Yukihiko, M., Kenji, K., Naoyuki, T., Hisayuki, M., Hiroshi, Y. & Naotake, O., Dec 15 1988, In: Gene. 73, 1, p. 1-9 9 p.

  Research output: Contribution to journal › Article › peer-review

  • gamma-Glutamyltransferase
  • Complementary DNA
  • Light
  • Amino Acids
  • Amino Acid Sequence
  55 Scopus citations