Research Output per year
Research Output 1988 2019
Loss of the tumor suppressor BIN1 enables ATM Ser/Thr kinase activation by the nuclear protein E2F1 and renders cancer cells resistant to cisplatin
Folk, W. P., Kumari, A., Iwasaki, T., Pyndiah, S., Johnson, J. C., Cassimere, E. K., Abdulovic-Cui, A. L. & Sakamuro, D., Jan 1 2019, In : Journal of Biological Chemistry. 294, 14, p. 5700-5719 20 p.Research output: Contribution to journal › Article
Endocrine disruptor exposure during development increases incidence of uterine fibroids by altering DNA repair in myometrial stem cells
Prusinski Fernung, L., Yang, Q., Sakamuro, D., Kumari, A., Mas, A. & Al-Hendy, A., Oct 1 2018, In : Biology of reproduction. 99, 4, p. 735-748 14 p.Research output: Contribution to journal › Article
Regulation of E2F1-induced apoptosis by poly(ADP-ribosyl)ation
Kumari, A., Iwasaki, T., Pyndiah, S., Cassimere, E. K., Palani, C. D. & Sakamuro, D., Feb 1 2015, In : Cell Death and Differentiation. 22, 2, p. 311-322 12 p.Research output: Contribution to journal › Article
Restoration of tumor suppressor functions by small-molecule inhibitors
Pyndiah, S. & Sakamuro, D., Jul 3 2015, In : Molecular and Cellular Oncology. 2, 3, e991225.Research output: Contribution to journal › Article
To die, or not to die: E2F1 never decides by itself during serum starvation
Sakamuro, D., Folk, W. P. & Kumari, A., Apr 3 2015, In : Molecular and Cellular Oncology. 2, 2, e981447.Research output: Contribution to journal › Article
Un trio de choc pour pallier la chimiorésistance des cancers c-MYC, PARP1, BIN1
Research output: Contribution to journal › Article
c-MYC suppresses BIN1 to release poly(ADP-ribose) polymerase 1: A mechanism by which cancer cells acquire cisplatin resistance
Pyndiah, S., Tanida, S., Ahmed, K. M., Cassimere, E. K., Choe, C. & Sakamuro, D., Mar 29 2011, In : Science Signaling. 4, 166, ra19.Research output: Contribution to journal › Article
Identification of a novel effector domain of BIN1 for cancer suppression
Lundgaard, G. L., Daniels, N. E., Pyndiah, S., Cassimere, E. K., Ahmed, K. M., Rodrigue, A., Kihara, D., Post, C. B. & Sakamuro, D., Oct 1 2011, In : Journal of cellular biochemistry. 112, 10, p. 2992-3001 10 p.Research output: Contribution to journal › Article
The c-MYC-interacting proapoptotic tumor suppressor BIN1 is a transcriptional target for E2F1 in response to DNA damage
Cassimere, E. K., Pyndiah, S. & Sakamuro, D., Jul 27 2009, In : Cell Death and Differentiation. 16, 12, p. 1641-1653 13 p.Research output: Contribution to journal › Article
Adenovirus E1A oncoprotein liberates c-Myc activity to promote cell proliferation through abating Bin1 expression via an Rb/E2F1-dependent mechanism
Kinney, E. L., Tanida, S., Rodrigue, A. A., Johnson, J. K., Tompkins, V. S. & Sakamuro, D., Sep 1 2008, In : Journal of Cellular Physiology. 216, 3, p. 621-631 11 p.Research output: Contribution to journal › Article
Bin1 attenuation in breast cancer is correlated to nodal metastasis and reduced survival
Ghaneie, A., Zemba-Palko, V., Itoh, H., Itoh, K., Sakamuro, D., Nakamura, S., Soler, A. P. & Prendergast, G. C., Jan 1 2007, In : Cancer Biology and Therapy. 6, 2, p. 192-194 3 p.Research output: Contribution to journal › Article
Induction of Fas (CD95/APO-1) ligand is essential for p53-dependent apoptosis in an in vitro renal carcinoma model system
Okazaki, T. & Sakamuro, D., Sep 1 2007, In : Journal of Cancer Research and Clinical Oncology. 133, 9, p. 581-588 8 p.Research output: Contribution to journal › Article
Bin1 mediates apoptosis by c-Myc in transformed primary cells
DuHadaway, J. B., Sakamuro, D., Ewert, D. L. & Prendergast, G. C., Apr 1 2001, In : Cancer Research. 61, 7, p. 3151-3156 6 p.Research output: Contribution to journal › Article
Losses of the tumor suppressor BIN1 in breast carcinoma are frequent and reflect deficits in programmed cell death capacity
Ge, K., Duhadaway, J., Sakamuro, D., Wechsler-Reya, R., Reynolds, C. & Prendergast, G. C., Jan 17 2000, In : International Journal of Cancer. 85, 3, p. 376-383 8 p.Research output: Contribution to journal › Article
Loss of heterozygosity and tumor suppressor activity of BIN1 in prostate carcinoma
Ge, K., Minhas, F., Duhadaway, J., Mao, N. C., Wilson, D., Buccafusca, R., Sakamuro, D., Nelson, P., Malkowicz, S. B., Tomaszewski, J. & Prendergast, G. C., Apr 12 2000, In : International Journal of Cancer. 86, 2, p. 155-161 7 p.Research output: Contribution to journal › Article
Bin1 functionally interacts with Myc and inhibits cell proliferation via multiple mechanisms
Elliott, K., Sakamuro, D., Basu, A., Du, W., Wunner, W., Staller, P., Gaubatz, S., Zhang, H., Prochownik, E., Eilers, M. & Prendergast, G. C., Jun 17 1999, In : Oncogene. 18, 24, p. 3564-3573 10 p.Research output: Contribution to journal › Article
Farnesyl transferase inhibitors induce apoptosis of Ras-transformed cells denied substratum attachment
Lebowitz, P. F., Sakamuro, D. & Prendergast, G. C., Mar 3 1997, In : Cancer Research. 57, 4, p. 708-713 6 p.Research output: Contribution to journal › Article
Structural analysis of the human BIN1 gene: Evidence for tissue-specific transcriptional regulation and alternate RNA splicing
Wechsler-Reya, R., Sakamuro, D., Zhang, J., Duhadaway, J. & Prendergast, G. C., Dec 12 1997, In : Journal of Biological Chemistry. 272, 50, p. 31453-31458 6 p.Research output: Contribution to journal › Article
The polyproline region of p53 is required to activate apoptosis but not growth arrest
Sakamuro, D., Sabbatini, P., White, E. & Prendergast, G. C., Jan 1 1997, In : Oncogene. 15, 8, p. 887-898 12 p.Research output: Contribution to journal › Article
BIN1 is a novel MYC-interacting protein with features of a tumour suppressor
Sakamuro, D., Elliott, K. J., Wechsler-Reya, R. & Prendergast, G. C., Sep 1 1996, In : Nature Genetics. 14, 1, p. 69-77 9 p.Research output: Contribution to journal › Article
Detection of a unique γ-glutamyl transpeptidase messenger RNA species closely related to the development of hepatocellular carcinoma in humans: A new candidate for early diagnosis of hepatocellular carcinoma
Tsutsumi, M., Sakamuro, D., Takada, A., Zang, S. C., Furukawa, T. & Taniguchi, N., Jan 1 1996, In : Hepatology. 23, 5, p. 1093-1097 5 p.Research output: Contribution to journal › Article
The Bin1 gene localizes to human chromosome 2q14 by PCR analysis of somatic cell hybrids and fluorescence in situ hybridization
Negorev, D., Riethman, H., Wechsler-Reya, R., Sakamuro, D., Prendergast, G. C. & Simon, D., Apr 15 1996, In : Genomics. 33, 2, p. 329-331 3 p.Research output: Contribution to journal › Article
c-Myc induces apoptosis in epithelial cells by both p53-dependent and p53-independent mechanisms
Sakamuro, D., Eviner, V., Elliott, K. J., Showe, L., White, E. & Prendergast, G. C., Dec 7 1995, In : Oncogene. 11, 11, p. 2410-2418 9 p.Research output: Contribution to journal › Article
Hepatitis C virus nonstructural protein NS3 transforms NIH 3T3 cells
Sakamuro, D., Furukawa, T. & Takegami, T., Jan 1 1995, In : Journal of Virology. 69, 6, p. 3893-3896 4 p.Research output: Contribution to journal › Article
Japanese encephalitis virus nonstructural protein NS3 has RNA binding and ATPase activities
Takegami, T., Sakamuro, D. & Furukawa, T., Jan 1 1995, In : Virus Genes. 9, 2, p. 105-112 8 p.Research output: Contribution to journal › Article
Detection of human cytomegalovirus genome in uterus tissue
Furukawa, T., Jisaki, F., Sakamuro, D., Takegami, T. & Murayama, T., Sep 1 1994, In : Archives of Virology. 135, 3-4, p. 265-277 13 p.Research output: Contribution to journal › Article
Different antibody response to a neutralizing epitope of human cytomegalovirus glycoprotein B among seropositive individuals
Ayata, M., Sugano, T., Murayama, T., Sakamuro, D., Takegami, T., Matsumoto, YI. I. & Furukawa, T., Jan 1 1994, In : Journal of Medical Virology. 43, 4, p. 386-392 7 p.Research output: Contribution to journal › Article
Elevated cytokine levels in synovial fluid of rheumatoid arthritis correlates with the presence of cytomegalovirus genome
Murayama, T., Tsuchiya, N., Jisaki, F., Ozaki, M., Sakamuro, D., Hirai, K., Shimizu, S., Ito, K., Matsushima, K. & Furukawa, T., Jan 1 1994, In : Autoimmunity. 17, 4, p. 333-337 5 p.Research output: Contribution to journal › Article
Cytomegalovirus genomes demonstrates by polymerase chain reaction in synovial fluid from rheumatoid arthritis patients
Murayama, T., Jisaki, F., Ayata, M., Sakamuro, D., Hironaka, T., Hirai, K., Tsuchiya, N., Ito, K. & Furukawa, T., Jan 1 1992, In : Clinical and Experimental Rheumatology. 10, 2, p. 161-164 4 p.Research output: Contribution to journal › Article
Synthesis of human gamma-glutamyl transpeptidase (GGT) during the fetal development of liver
Shiozawa, M., Hiraoka, Y., Yasuda, K., Imamura, T., Sakamuro, D., Taniguchi, N., Yamazoe, M. & Yoshikawa, H., Mar 15 1990, In : Gene. 87, 2, p. 299-303 5 p.Research output: Contribution to journal › Article
Polymorphonuclear cell factor found in patients with rheumatoid arthritis
Wakitani, S., Sakamuro, D., Ochi, T., Owaki, H., Fujimoto, M. & Ono, K., Jan 1 1988, In : Biomedical Research. 9, 5, p. 395-399 5 p.Research output: Contribution to journal › Article
The primary structure of human gamma-glutamyl transpeptidase
Sakamuro, D., Mitsuyoshi, Y., Yukihiko, M., Kenji, K., Naoyuki, T., Hisayuki, M., Hiroshi, Y. & Naotake, O., Dec 15 1988, In : Gene. 73, 1, p. 1-9 9 p.Research output: Contribution to journal › Article