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Daitoku Sakamuro

Associate Professor

  • 2218 Citations
  • 21 h-Index
1988 …2019

Research output per year

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Research Output

  • 2218 Citations
  • 21 h-Index
  • 32 Article
  • 3 Review article
  • 1 Comment/debate
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Article
2019

Loss of the tumor suppressor BIN1 enables ATM Ser/Thr kinase activation by the nuclear protein E2F1 and renders cancer cells resistant to cisplatin

Folk, W. P., Kumari, A., Iwasaki, T., Pyndiah, S., Johnson, J. C., Cassimere, E. K., Abdulovic-Cui, A. L. & Sakamuro, D., Apr 5 2019, In : Journal of Biological Chemistry. 294, 14, p. 5700-5719 20 p.

Research output: Contribution to journal › Article

5 Scopus citations
2018

Endocrine disruptor exposure during development increases incidence of uterine fibroids by altering DNA repair in myometrial stem cells

Prusinski Fernung, L., Yang, Q., Sakamuro, D., Kumari, A., Mas, A. & Al-Hendy, A., Oct 1 2018, In : Biology of reproduction. 99, 4, p. 735-748 14 p.

Research output: Contribution to journal › Article

4 Scopus citations
2015

Regulation of E2F1-induced apoptosis by poly(ADP-ribosyl)ation

Kumari, A., Iwasaki, T., Pyndiah, S., Cassimere, E. K., Palani, C. D. & Sakamuro, D., Feb 1 2015, In : Cell Death and Differentiation. 22, 2, p. 311-322 12 p.

Research output: Contribution to journal › Article

19 Scopus citations

Restoration of tumor suppressor functions by small-molecule inhibitors

Pyndiah, S. & Sakamuro, D., Jul 3 2015, In : Molecular and Cellular Oncology. 2, 3, e991225.

Research output: Contribution to journal › Article

To die, or not to die: E2F1 never decides by itself during serum starvation

Sakamuro, D., Folk, W. P. & Kumari, A., Apr 3 2015, In : Molecular and Cellular Oncology. 2, 2, e981447.

Research output: Contribution to journal › Article

2 Scopus citations
2013

Un trio de choc pour pallier la chimiorésistance des cancers c-MYC, PARP1, BIN1

Translated title of the contribution: C-MYC, PARP1 and BIN1 as targets for therapy of cancer cell resistancePyndiah, S. & Sakamuro, D., Feb 1 2013, In : Medecine/Sciences. 29, 2, p. 133-135 3 p.

Research output: Contribution to journal › Article

5 Scopus citations
2011

c-MYC suppresses BIN1 to release poly(ADP-ribose) polymerase 1: A mechanism by which cancer cells acquire cisplatin resistance

Pyndiah, S., Tanida, S., Ahmed, K. M., Cassimere, E. K., Choe, C. & Sakamuro, D., Mar 29 2011, In : Science Signaling. 4, 166, ra19.

Research output: Contribution to journal › Article

57 Scopus citations

Identification of a novel effector domain of BIN1 for cancer suppression

Lundgaard, G. L., Daniels, N. E., Pyndiah, S., Cassimere, E. K., Ahmed, K. M., Rodrigue, A., Kihara, D., Post, C. B. & Sakamuro, D., Oct 1 2011, In : Journal of cellular biochemistry. 112, 10, p. 2992-3001 10 p.

Research output: Contribution to journal › Article

9 Scopus citations
2009

The c-MYC-interacting proapoptotic tumor suppressor BIN1 is a transcriptional target for E2F1 in response to DNA damage

Cassimere, E. K., Pyndiah, S. & Sakamuro, D., Jul 27 2009, In : Cell Death and Differentiation. 16, 12, p. 1641-1653 13 p.

Research output: Contribution to journal › Article

25 Scopus citations
2008

Adenovirus E1A oncoprotein liberates c-Myc activity to promote cell proliferation through abating Bin1 expression via an Rb/E2F1-dependent mechanism

Kinney, E. L., Tanida, S., Rodrigue, A. A., Johnson, J. K., Tompkins, V. S. & Sakamuro, D., Sep 2008, In : Journal of Cellular Physiology. 216, 3, p. 621-631 11 p.

Research output: Contribution to journal › Article

15 Scopus citations
2007

Bin1 attenuation in breast cancer is correlated to nodal metastasis and reduced survival

Ghaneie, A., Zemba-Palko, V., Itoh, H., Itoh, K., Sakamuro, D., Nakamura, S., Soler, A. P. & Prendergast, G. C., Feb 2007, In : Cancer Biology and Therapy. 6, 2, p. 192-194 3 p.

Research output: Contribution to journal › Article

21 Scopus citations

Induction of Fas (CD95/APO-1) ligand is essential for p53-dependent apoptosis in an in vitro renal carcinoma model system

Okazaki, T. & Sakamuro, D., Sep 1 2007, In : Journal of Cancer Research and Clinical Oncology. 133, 9, p. 581-588 8 p.

Research output: Contribution to journal › Article

7 Scopus citations
2001

Bin1 mediates apoptosis by c-Myc in transformed primary cells

DuHadaway, J. B., Sakamuro, D., Ewert, D. L. & Prendergast, G. C., Apr 1 2001, In : Cancer Research. 61, 7, p. 3151-3156 6 p.

Research output: Contribution to journal › Article

65 Scopus citations
2000

Losses of the tumor suppressor BIN1 in breast carcinoma are frequent and reflect deficits in programmed cell death capacity

Ge, K., Duhadaway, J., Sakamuro, D., Wechsler-Reya, R., Reynolds, C. & Prendergast, G. C., Jan 17 2000, In : International Journal of Cancer. 85, 3, p. 376-383 8 p.

Research output: Contribution to journal › Article

77 Scopus citations

Loss of heterozygosity and tumor suppressor activity of BIN1 in prostate carcinoma

Ge, K., Minhas, F., Duhadaway, J., Mao, N. C., Wilson, D., Buccafusca, R., Sakamuro, D., Nelson, P., Malkowicz, S. B., Tomaszewski, J. & Prendergast, G. C., Apr 12 2000, In : International Journal of Cancer. 86, 2, p. 155-161 7 p.

Research output: Contribution to journal › Article

77 Scopus citations
1999

Bin1 functionally interacts with Myc and inhibits cell proliferation via multiple mechanisms

Elliott, K., Sakamuro, D., Basu, A., Du, W., Wunner, W., Staller, P., Gaubatz, S., Zhang, H., Prochownik, E., Eilers, M. & Prendergast, G. C., Jun 17 1999, In : Oncogene. 18, 24, p. 3564-3573 10 p.

Research output: Contribution to journal › Article

91 Scopus citations
1997

Farnesyl transferase inhibitors induce apoptosis of Ras-transformed cells denied substratum attachment

Lebowitz, P. F., Sakamuro, D. & Prendergast, G. C., Mar 3 1997, In : Cancer Research. 57, 4, p. 708-713 6 p.

Research output: Contribution to journal › Article

175 Scopus citations

Structural analysis of the human BIN1 gene: Evidence for tissue-specific transcriptional regulation and alternate RNA splicing

Wechsler-Reya, R., Sakamuro, D., Zhang, J., Duhadaway, J. & Prendergast, G. C., Dec 12 1997, In : Journal of Biological Chemistry. 272, 50, p. 31453-31458 6 p.

Research output: Contribution to journal › Article

107 Scopus citations

The polyproline region of p53 is required to activate apoptosis but not growth arrest

Sakamuro, D., Sabbatini, P., White, E. & Prendergast, G. C., Jan 1 1997, In : Oncogene. 15, 8, p. 887-898 12 p.

Research output: Contribution to journal › Article

236 Scopus citations
1996

BIN1 is a novel MYC-interacting protein with features of a tumour suppressor

Sakamuro, D., Elliott, K. J., Wechsler-Reya, R. & Prendergast, G. C., Sep 1 1996, In : Nature Genetics. 14, 1, p. 69-77 9 p.

Research output: Contribution to journal › Article

283 Scopus citations

Detection of a unique γ-glutamyl transpeptidase messenger RNA species closely related to the development of hepatocellular carcinoma in humans: A new candidate for early diagnosis of hepatocellular carcinoma

Tsutsumi, M., Sakamuro, D., Takada, A., Zang, S. C., Furukawa, T. & Taniguchi, N., Jan 1 1996, In : Hepatology. 23, 5, p. 1093-1097 5 p.

Research output: Contribution to journal › Article

46 Scopus citations

The Bin1 gene localizes to human chromosome 2q14 by PCR analysis of somatic cell hybrids and fluorescence in situ hybridization

Negorev, D., Riethman, H., Wechsler-Reya, R., Sakamuro, D., Prendergast, G. C. & Simon, D., Apr 15 1996, In : Genomics. 33, 2, p. 329-331 3 p.

Research output: Contribution to journal › Article

23 Scopus citations
1995

c-Myc induces apoptosis in epithelial cells by both p53-dependent and p53-independent mechanisms

Sakamuro, D., Eviner, V., Elliott, K. J., Showe, L., White, E. & Prendergast, G. C., Dec 7 1995, In : Oncogene. 11, 11, p. 2410-2418 9 p.

Research output: Contribution to journal › Article

153 Scopus citations

Hepatitis C virus nonstructural protein NS3 transforms NIH 3T3 cells

Sakamuro, D., Furukawa, T. & Takegami, T., Jan 1 1995, In : Journal of Virology. 69, 6, p. 3893-3896 4 p.

Research output: Contribution to journal › Article

276 Scopus citations

Japanese encephalitis virus nonstructural protein NS3 has RNA binding and ATPase activities

Takegami, T., Sakamuro, D. & Furukawa, T., Jan 1 1995, In : Virus Genes. 9, 2, p. 105-112 8 p.

Research output: Contribution to journal › Article

37 Scopus citations
1994

Detection of human cytomegalovirus genome in uterus tissue

Furukawa, T., Jisaki, F., Sakamuro, D., Takegami, T. & Murayama, T., Sep 1 1994, In : Archives of Virology. 135, 3-4, p. 265-277 13 p.

Research output: Contribution to journal › Article

23 Scopus citations

Different antibody response to a neutralizing epitope of human cytomegalovirus glycoprotein B among seropositive individuals

Ayata, M., Sugano, T., Murayama, T., Sakamuro, D., Takegami, T., Matsumoto, YI. I. & Furukawa, T., Aug 1994, In : Journal of Medical Virology. 43, 4, p. 386-392 7 p.

Research output: Contribution to journal › Article

11 Scopus citations

Elevated cytokine levels in synovial fluid of rheumatoid arthritis correlates with the presence of cytomegalovirus genome

Murayama, T., Tsuchiya, N., Jisaki, F., Ozaki, M., Sakamuro, D., Hirai, K., Shimizu, S., Ito, K., Matsushima, K. & Furukawa, T., Jan 1 1994, In : Autoimmunity. 17, 4, p. 333-337 5 p.

Research output: Contribution to journal › Article

11 Scopus citations
1992

Cytomegalovirus genomes demonstrates by polymerase chain reaction in synovial fluid from rheumatoid arthritis patients

Murayama, T., Jisaki, F., Ayata, M., Sakamuro, D., Hironaka, T., Hirai, K., Tsuchiya, N., Ito, K. & Furukawa, T., Jan 1 1992, In : Clinical and Experimental Rheumatology. 10, 2, p. 161-164 4 p.

Research output: Contribution to journal › Article

21 Scopus citations
1990

Synthesis of human gamma-glutamyl transpeptidase (GGT) during the fetal development of liver

Shiozawa, M., Hiraoka, Y., Yasuda, K., Imamura, T., Sakamuro, D., Taniguchi, N., Yamazoe, M. & Yoshikawa, H., Mar 15 1990, In : Gene. 87, 2, p. 299-303 5 p.

Research output: Contribution to journal › Article

10 Scopus citations
1988

Polymorphonuclear cell factor found in patients with rheumatoid arthritis

Wakitani, S., Sakamuro, D., Ochi, T., Owaki, H., Fujimoto, M. & Ono, K., Jan 1 1988, In : Biomedical Research. 9, 5, p. 395-399 5 p.

Research output: Contribution to journal › Article

2 Scopus citations

The primary structure of human gamma-glutamyl transpeptidase

Daitoku, S., Mitsuyoshi, Y., Yukihiko, M., Kenji, K., Naoyuki, T., Hisayuki, M., Hiroshi, Y. & Naotake, O., Dec 15 1988, In : Gene. 73, 1, p. 1-9 9 p.

Research output: Contribution to journal › Article

54 Scopus citations