David C Hess

EVP, Med Affairs & Dean, MCG

  • 11346 Citations
  • 58 h-Index
1989 …2020

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output

1989

Antiphospholipid antibodies in stroke.

Hess, D. C., Adams, R. J. & Nichols, F. T., Dec 1 1989, In : Journal of the Medical Association of Georgia. 78, 12, p. 815-820 6 p.

Research output: Contribution to journalArticle

1990

Carotid dissection: A new false localising sign

Hess, D. C., Sethi, K. D. & Nichols, F. T., 1990, In : Journal of Neurology Neurosurgery and Psychiatry. 53, 9, p. 804-805 2 p.

Research output: Contribution to journalLetter

19 Scopus citations

Clinical and laboratory findings in patients with antiphospholipid antibodies and cerebral ischemia

The Antiphospholipid Antibodies in Stroke Study Group, Sep 1990, In : Stroke. 21, 9, p. 1268-1273 6 p.

Research output: Contribution to journalArticle

173 Scopus citations

Comparative Neuroimaging With Pathologic Correlates in Alexander's Disease

Hess, D. C., Fischer, A. Q., Yaghmai, F., Figueroa Ortiz, R. E. & Akamatsu, Y., Jan 1 1990, In : Journal of Child Neurology. 5, 3, p. 248-252 5 p.

Research output: Contribution to journalArticle

15 Scopus citations

Epilepsia partialis continua in multiple sclerosis

Hess, D. C. & Sethi, K. D., Jan 1 1990, In : International Journal of Neuroscience. 50, 1-2, p. 109-111 3 p.

Research output: Contribution to journalArticle

14 Scopus citations

Gaze‐evoked involuntary movement

Sethi, K. D., Hess, D. C., Harbour, R. C. & Holmes, G. L., 1990, In : Movement Disorders. 5, 2, p. 139-142 4 p.

Research output: Contribution to journalArticle

7 Scopus citations

Hyperammonemia in women with a mutation at the ornithine carbamoyltransferase locus: A Cause of Postpartum Coma

Arn, P. H., Hauser, E. R., Thomas, G. H., Herman, G., Hess, D. & Brusilow, S. W., Jun 7 1990, In : New England Journal of Medicine. 322, 23, p. 1652-1655 4 p.

Research output: Contribution to journalArticle

145 Scopus citations

Miller Fisher syndrome in systemic lupus erythematosus

Hess, D. C., Awad, E., Posas, H., Sethi, K. D. & Adams, R. J., Jan 1 1990, In : Journal of Rheumatology. 17, 11, p. 1520-1522 3 p.

Research output: Contribution to journalArticle

14 Scopus citations

Prevalence of dystonia in veterans on chronic antipsychotic therapy

Sethi, K. D., Hess, D. C. & Harp, R. J., 1990, In : Movement Disorders. 5, 4, p. 319-321 3 p.

Research output: Contribution to journalArticle

35 Scopus citations
1991

Anticardiolipin antibodies: A study of frequency in TIA and stroke

Hess, D. C., Krauss, J., Adams, R. J., Nichols, F. T., Zhang, D. I. & Rountree, H. A., Apr 1991, In : Neurology. 41, 4, p. 525-528 4 p.

Research output: Contribution to journalArticle

58 Scopus citations

Creutzfeldt‐Jakob's disease presenting with ataxia and a movement disorder

Sethi, K. D. & Hess, D. C., Jan 1 1991, In : Movement Disorders. 6, 2, p. 157-162 6 p.

Research output: Contribution to journalArticle

12 Scopus citations

Sickle cell anemia and other hemoglobinopathies

Hess, D. C., Adams, R. J. & Nichols, F. T., Jan 1 1991, In : Seminars in Neurology. 11, 4, p. 314-328 15 p.

Research output: Contribution to journalReview article

13 Scopus citations

Species variation in pulmonary endothelial aminopeptidase P activity

Chen, X., Orfanos, S. E., Ryan, J. W., Chung, A. Y. K., Hess, D. C. & Catravas, J. D., 1991, In : Journal of Pharmacology and Experimental Therapeutics. 259, 3, p. 1301-1307 7 p.

Research output: Contribution to journalArticle

14 Scopus citations

Stroke in a young adult with Fletcher trait

Hess, D. C., Krauss, J. S. & Rardin, D., Jan 1 1991, In : Southern medical journal. 84, 4, p. 507-508 2 p.

Research output: Contribution to journalArticle

15 Scopus citations

Transient cerebral ischemia masquerading as paroxysmal dyskinesia

Hess, D. C., Nichols, F. T., Sethi, K. D. & Adams, R. J., Jan 1 1991, In : Cerebrovascular Diseases. 1, 1, p. 54-57 4 p.

Research output: Contribution to journalArticle

9 Scopus citations
1992

Acetazolamide treatment of paroxysmal dystonia in central demyelinating disease

Sethi, K. D., Hess, D. C., Huffnagle, V. H. & Adams, R. J., Apr 1992, In : Neurology. 42, 4, p. 919-921 3 p.

Research output: Contribution to journalArticle

38 Scopus citations

Stroke associated with antiphospholipid antibodies

Hess, D. C., Feb 1992, In : Stroke. 23, 2, p. I-23-I-28

Research output: Contribution to journalArticle

43 Scopus citations

The use of transcranial ultrasonography to predict stroke in sickle cell disease

Adams, R., Nichols, F., Carl, E., Zhang, D. L., Hess, D., Mckie, V., Mckie, K., Figueroa, R., Litaker, M. & Thompson, W., Feb 27 1992, In : New England Journal of Medicine. 326, 9, p. 605-610 6 p.

Research output: Contribution to journalArticle

472 Scopus citations
50 Scopus citations
1993

Anticardiolipin antibodies and hypercoagulability [3]

Anand, A., Hess, D. C., Liang, M. H., Hennekens, C. H. & Stampfer, M. J., Jan 1 1993, In : Annals of internal medicine. 118, 12, p. 986-987 2 p.

Research output: Contribution to journalLetter

1 Scopus citations

Clinical, radiological, and pathological aspects of cerebrovascular disease associated with antiphospholipid antibodies

Kittner, S., Joseph, C., Levine, S. R., Sawaya, K., Palm, L., Carey, J., Deegan, M., Brey, R., Davis, W., Kaste, J., McGlasson, D., McAtee, R., Feldmann, E., Friedberg, K., Stem, B., Karanjia, P., Jacobson, D., Lobner, S., Hess, D., Adams, R. & 20 others, Weinberger, J., Dunn, M., Horowitz, D., Tuhrim, S., Fayad, P., Brass, L. M., Hwang, T. L., Trijillano, A., Babikian, V., Hersey, H., Sloan, M., Fetzer, D. E., Coull, B., Briley, D., deGarmo, P., Gomez, C., Jedlicka, M., Fisher, M., Doyle, E. & DeWitt, D. D., Dec 1993, In : Stroke. 24, 12, p. I-120-I-123

Research output: Contribution to journalArticle

23 Scopus citations

Cognitive and neurologic deficits in the MRL/lpr mouse: A clinicopathologic study

Hess, D. C., Taormina, M., Thompson, J., Sethi, K. D., Diamond, B., Rao, R., Chamberlain, C. R. & Feldman, D. S., Jan 1 1993, In : Journal of Rheumatology. 20, 4, p. 610-617 8 p.

Research output: Contribution to journalArticle

83 Scopus citations

Coronary artery disease, myocardial infarction, and brain embolism

Hess, D. C., D'Cruz, I. A., Adams, R. J. & Nichols, F. T., 1993, In : Neurologic Clinics. 11, 2, p. 399-417 19 p.

Research output: Contribution to journalReview article

25 Scopus citations

Increased immunoglobulin binding to cerebral endothelium in patients with antiphospholipid antibodies

Hess, D. C., Sheppard, J. C. & Adams, R. J., Jul 1993, In : Stroke. 24, 7, p. 994-999 6 p.

Research output: Contribution to journalArticle

41 Scopus citations

Thrombotic thrombocytopenic purpura in systemic lupus erythematosus [3]

Porta, C., Bobbio-Pallavicini, E., Centurioni, R., Caporali, R., Montecucco, C. M., Hess, D. C. & Sethi, K. D., Dec 1 1993, In : Journal of Rheumatology. 20, 9, p. 1625-1626 2 p.

Research output: Contribution to journalLetter

29 Scopus citations
1994

Anticardiolipin antibodies in MS patients

Scott, F., Brillman, J., Romanelli, J. & Hess, D., Nov 1994, In : Acta Neurologica Scandinavica. 90, 5, p. 374 1 p.

Research output: Contribution to journalLetter

2 Scopus citations

Antiphospholipid antibody syndrome mimicking multiple sclerosis clinically and by magnetic resonance imaging

Scott, T. F., Hess, D. & Brillman, J., Apr 25 1994, In : Archives of Internal Medicine. 154, 8, p. 917-920 4 p.

Research output: Contribution to journalArticle

52 Scopus citations

ICAM-1 expression on human brain microvascular endothelial cells

Hess, D. C., Bhutwala, T., Sheppard, J. C., Zhao, W. & Smith, J., Feb 28 1994, In : Neuroscience Letters. 168, 1-2, p. 201-204 4 p.

Research output: Contribution to journalArticle

63 Scopus citations

Increased expression of icam-1 during reoxygenation in brain endothelial cells

Hess, D. C., Zhao, W., Carroll, J. E., McEachin, M. & Buchanan, K., Jul 1994, In : Stroke. 25, 7, p. 1463-1467 5 p.

Research output: Contribution to journalArticle

77 Scopus citations

Models for Central Nervous System Complications of Antiphospholipid Syndrome

Hess, D. C., Aug 1994, In : Lupus. 3, 4, p. 253-257 5 p.

Research output: Contribution to journalArticle

6 Scopus citations

Postdischarge survival and functional status following in-hospital cardiopulmonary resuscitation

Robinson, G. R. & Hess, D., 1994, In : CHEST. 105, 4, p. 991-996 6 p.

Research output: Contribution to journalArticle

63 Scopus citations

Safety study of tirilazad mesylate in patients with acute ischemic stroke (Stipas)

Putman, S., Anderson, F., Morrison, M. R., Turtle, P., Passini, B. T., Wilner, A. N., Allen, F. H., Adams, R., Carl, B., Bueke, C., Nichols, F. T., Hess, D. C., Hyder, S., Burch, G., Foley, C., Bivins, D. H., Wilson, J. T., Sisk, M. A., Nolan, D. B., Elias, W. S. & 28 others, Sheppard, G. L., Crowe, N. F., Massey, S., Hurst, D., Zontine, D., Gustin, K. H., Haley, E. C., McClure, K., Granner, M., Wolf, S., Gwynn, M., Mettetal, R. W., Haley, E. C., Tomer, J. C., Kongable, G., Wilkinson, S., Apperson Hansen, C., Wolff, M. C., Gibson, R. S., Bergin, J. D., Truskowski, L., Lightfoot, G., Lightfoot, A., Polin, A., Solenski, N. J., Stiteler, J., Peters, G. R. & Bryan, W. J., Feb 1994, In : Stroke. 25, 2, p. 418-423 6 p.

Research output: Contribution to journalArticle

64 Scopus citations
1996

Adjusted-dose warfarin versus low-intensity, fixed-dose warfarin plus aspirin for high-risk patients with atrial fibrillation: Stroke prevention in Atrial Fibrillation III Randomised Clinical Trial

Blackshear, J. L., Baker, V. S., Rubino, F., Safford, R., Lane, G., Flipse, T., Malouf, J., Thompson, R., Webel, R., Flaker, G. C., Young, L., Hess, D. C., Friedman, G., Burger, R., McAnulty, J. H., Coull, B. M., Marchant, C., Timberg, J., Janzik, C., Giraud, G. & 142 others, Halperin, B., Kron, J., Wynn, M., Raitt, M., Anderson, D. C., Asinger, R. W., Newburg, S. M., Fifield, J., Bundlie, S. R., Koller, R. L., Tarrel, R. D., Dick, C., Haugland, J. M., Jorgensen, C. R., Leonard, A. D., Kanter, M. C., Solomon, D. H., Zabalgoitia, M., Mego, D., Carter, J. E., Boyd, S. Y., Boop, B. S., LaLonde, D., Modlin, R., Logan, W. R., Green, B. J., Hamilton, W. P., Mezei, L., Riggio, S., Feldman, G., Hayward, A., Strauss, R., Anderson, W., Grover, J., McKenzie, M., Hart-McArthur, P., Gramberg, M., Houston, H., Halperin, J. L., Rothauf, E. B., Weinberger, J. M., Goldman, M. E., Laupacis, A., Chan, K. L., Bourque, P., Biggs, J., Ives, A., Feinberg, W. M., Kern, K. B., Pennock, G. D., Fenster, P. E., Huerta, B. J., Ohm, J., Dittrich, H. C., Kerridge, C., Keen, W., Swenson, M., Kopecky, S. L., Litin, S. C., Wiebers, D. O., Holland, A. E., Brown, R. D., Khandheria, B. K., Meissner, I., Tucker, K. R., Rothbart, R., Torelli, J., Schmidt, J., Murray, D., Ruzich, R. S., Loutfi, H., Appleton, C., Ingall, T., Carlson, L., Wilson, D., Dunn, M., Nolte, B., Edwards, C., Dick, A., Price, L. A., Janosik, D. L., Bjerregaard, P., Quattromani, A., Schiller, L., Labovitz, A., Burch, C., Parks, B. J., Thompson, D., Berarducci, L., Carey, S., Vigil, A., Falk, R., Battinelli, N., McNeil, M., Davidoff, R., Bernard, S., Bergethon, P., Fiori, L., Albers, G., Atwood, E., Clark, J., Tong, D., Yenari, M., Froelicker, V., Lutsep, H., Hock, N. H., Quaglietti, S., Kemp, S., Alpert, M. A., Rothrock, J. F., Hupp, C. H., Massey, C. V., Hamilton, W. J., Miller, V. T., Fox, J., Kronmal, R. A., McBride, R., Nasco, E., Pearce, L. A., Fletcher, K., Koehler, J., Hart, R. G., Sherman, D. G., Talbert, R. L., Heberling, P. A., Kajzer, C., Bovill, E., Geffken, D., Cornell, E., Nightingale, S., Blackshear, J. L., Halperin, J. L., Hart, R. G., Laupacis, A., McAnulty, J. H., McBride, R., Kelsy, S. P., Levy, D. E., Marsh, J. D., Welch, K. M. A., Marler, J. R. & Walker, M. D., Sep 7 1996, In : Lancet. 348, 9028, p. 633-638 6 p.

Research output: Contribution to journalArticle

1063 Scopus citations

E-Selectin expression on human brain microvascular endothelial cells

Hess, D. C., Thompson, Y., Sprinkle, A., Carroll, J. & Smith, J., Jul 26 1996, In : Neuroscience Letters. 213, 1, p. 37-40 4 p.

Research output: Contribution to journalArticle

26 Scopus citations
1997

Cerebral lupus vasculopathy: Mechanisms and clinical relevance

Hess, D. C., Jan 1 1997, In : Annals of the New York Academy of Sciences. 823, p. 154-168 15 p.

Research output: Contribution to journalArticle

44 Scopus citations
1998

NF-κB is activated and ICAM-1 gene expression is upregulated during reoxygenation of human brain endothelial cells

Howard, E. F., Chen, Q., Cheng, C., Carroll, J. E. & Hess, D., Jun 5 1998, In : Neuroscience Letters. 248, 3, p. 199-203 5 p.

Research output: Contribution to journalArticle

72 Scopus citations

Nuclear factor-κB activation during cerebral reperfusion: Effect of attenuation with N-acetylcysteine treatment

Carroll, J. E., Howard, E. F., Hess, D. C., Wakade, C. G., Chen, Q. & Cheng, C., May 1 1998, In : Molecular Brain Research. 56, 1-2, p. 186-191 6 p.

Research output: Contribution to journalArticle

91 Scopus citations
1999

Is cholesterol a risk factor for stroke? Yes

Demchuk, A. M., Hess, D. C., Brass, L. M. & Yatsu, F. M., Jan 1 1999, In : Archives of Neurology. 56, 12, p. 1518-1520 3 p.

Research output: Contribution to journalArticle

46 Scopus citations
2000

HMG-CoA reductase inhibitors (statins): A promising approach to stroke prevention

Hess, D. C., Demchuk, A. M., Brass, L. M. & Yatsu, F. M., Feb 22 2000, In : Neurology. 54, 4, p. 790-796 7 p.

Research output: Contribution to journalReview article

107 Scopus citations

HMG-CoA reductase inhibitors (statins): A promising approach to stroke prevention [1] (multiple letters)

Di Napoli, M., Hess, D. C., Demchuk, A. M., Brass, L. M. & Yatsu, F. M., Oct 10 2000, In : Neurology. 55, 7, p. 1066-1067 2 p.

Research output: Contribution to journalLetter

Hypertonic mannitol loading of NF-κ̄ transcription factor decoys in human brain microvascular endothelial cells blocks upregulation of ICAM-1

Hess, D. C., Howard, E., Cheng, C., Carroll, J. & Hill, D. W., May 2000, In : Stroke. 31, 5, p. 1179-1186 8 p.

Research output: Contribution to journalArticle

41 Scopus citations

Is nuclear factor-κB a good treatment target in brain ischemia/reperfusion injury?

Carroll, J. E., Hess, D. C., Howard, E. F. & Hill, W. D., Jun 26 2000, In : NeuroReport. 11, 9

Research output: Contribution to journalReview article

40 Scopus citations

Limb and hemispatial hypometria

Meador, K. J., Moore, E. E., Martin, R. C., Loring, D. W., Hess, D. C. & Heilman, K. M., Jan 2000, In : Journal of the International Neuropsychological Society. 6, 1, p. 71-75 5 p.

Research output: Contribution to journalArticle

2 Scopus citations

New help, new hope

Hess, D. C., May 1 2000, In : Consultant. 40, 6, p. 1085-1094 10 p.

Research output: Contribution to journalReview article

2001

Pharmacology and clinical experience with simvastatin

Hess, D. C. & Fagan, S. C., May 22 2001, In : Expert Opinion on Pharmacotherapy. 2, 1, p. 153-163 11 p.

Research output: Contribution to journalArticle

27 Scopus citations

The NF-κB inhibitor diethyldithiocarbamate (DDTC) increases brain cell death in a transient middle cerebral artery occlusion model of ischemia

Hill, W. D., Hess, D. C., Carroll, J. E., Wakade, C. G., Howard, E. F., Chen, Q., Cheng, C., Martin-Studdard, A., Waller, J. L. & Beswick, R. A., Aug 20 2001, In : Brain Research Bulletin. 55, 3, p. 375-386 12 p.

Research output: Contribution to journalArticle

56 Scopus citations

Use of anti-ICAM-1 therapy in ischemic stroke: Results of the enlimomab acute stroke trial

Sherman, D., Bes, A., Easton, J. D., Hacke, W., Kaste, M., Polmar, S. H., Zivin, J. A., Clark, W., Schneider, D., Whisnant, J., Fieschi, C., Miller, P., Schoenfeld, D., Street, J., Albers, G., Atkinson, R., Biller, J., Bruno, A., Carpenter, D., DeGraba, T. & 57 others, Driscoll, P., Ellis, J., Greenlee R., J., Hess, D. C., Horowitz, D. R., Davenport, J., Hsu, C., Starkman, S., Madden, K., Pettigrew, C., Rosenbaum, D., Schim, J., Tietjen, G., Mansbach, H., Edwards, K., Webb, R., Crisostomo, E., Wilterdrink, J., Rothrock, J., Zweifler, R., Dexter, J., Horowitz, S., Futrell, N., Alter, M., Ferbert, A., Prange, H., Wiersbitzky, M., Büttner, T., Schwartz, A., Busse, O., Klingelhöfer, J., Kaste, M., Erilä, T., Sivenius, J., Sotaniemi, K., Liukkonen, J., Hedman, C., Muuronen, A., Rissanen, A., Larrue, V., Blard, J. M., Caussanel, J. P., Feve, J. R., Moulin, T., Mahagne, M. H., Rancurel, G., Trouillas, P., Weber, M., Thomassen, L., Rosjø, Johnsen, H. J., Kjällman, L., Petersson, J., Ferrari, G., Lagi, A., Mamoli, A. & Re, G., Oct 23 2001, In : Neurology. 57, 8, p. 1428-1434 7 p.

Research output: Contribution to journalArticle

378 Scopus citations
2002

Acetoacetate increases expression of intercellular adhesion molecule-1 (ICAM-1) in human brain microvascular endothelial cells

Hoffman, W. H., Cheng, C., Passmore, G. G., Carroll, J. E. & Hess, D., Dec 13 2002, In : Neuroscience Letters. 334, 2, p. 71-74 4 p.

Research output: Contribution to journalArticle

35 Scopus citations

Bone marrow as a source of endothelial cells and NeuN-expressing cells after stroke

Hess, D. C., Hill, W. D., Martin-Studdard, A., Carroll, J., Brailer, J. & Carothers, J., May 27 2002, In : Stroke. 33, 5, p. 1362-1368 7 p.

Research output: Contribution to journalArticle

244 Scopus citations

Evaluating the comatose patient: Rapid neurologic assessment is key to appropriate management

Malik, K. & Hess, D. C., Jan 1 2002, In : Postgraduate medicine. 111, 2, p. 38-55 18 p.

Research output: Contribution to journalArticle

12 Scopus citations