David C Hess

EVP, Med Affairs & Dean, MCG

  • 11106 Citations
  • 58 h-Index
1989 …2020

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14 Scopus citations

Acetazolamide treatment of paroxysmal dystonia in central demyelinating disease

Sethi, K. D., Hess, D. C., Huffnagle, V. H. & Adams, R. J., Apr 1992, In : Neurology. 42, 4, p. 919-921 3 p.

Research output: Contribution to journalArticle

38 Scopus citations

Acetoacetate increases expression of intercellular adhesion molecule-1 (ICAM-1) in human brain microvascular endothelial cells

Hoffman, W. H., Cheng, C., Passmore, G. G., Carroll, J. E. & Hess, D., Dec 13 2002, In : Neuroscience Letters. 334, 2, p. 71-74 4 p.

Research output: Contribution to journalArticle

34 Scopus citations

Acute functional effects of cyclosporine-A and methylprednisolone treatment in adult rats exposed to transient ischemic stroke

Borlongan, C. V., Yu, G., Matsukawa, N., Xu, L., Hess, D. C., Sanberg, P. R. & Wang, Y., Feb 11 2005, In : Life sciences. 76, 13, p. 1503-1512 10 p.

Research output: Contribution to journalArticle

25 Scopus citations

Addressing Disparities in Stroke Prevention for Atrial Fibrillation: Educational Opportunities

Karcher, R., Berman, A. E., Gross, H., Hess, D. C., Jauch, E. C., Viser, P. E., Solenski, N. J. & Wolf, A. M. D., Jul 1 2016, In : American Journal of Medical Quality. 31, 4, p. 337-348 12 p.

Research output: Contribution to journalArticle

4 Scopus citations

Adjusted-dose warfarin versus low-intensity, fixed-dose warfarin plus aspirin for high-risk patients with atrial fibrillation: Stroke prevention in Atrial Fibrillation III Randomised Clinical Trial

Blackshear, J. L., Baker, V. S., Rubino, F., Safford, R., Lane, G., Flipse, T., Malouf, J., Thompson, R., Webel, R., Flaker, G. C., Young, L., Hess, D. C., Friedman, G., Burger, R., McAnulty, J. H., Coull, B. M., Marchant, C., Timberg, J., Janzik, C., Giraud, G. & 142 others, Halperin, B., Kron, J., Wynn, M., Raitt, M., Anderson, D. C., Asinger, R. W., Newburg, S. M., Fifield, J., Bundlie, S. R., Koller, R. L., Tarrel, R. D., Dick, C., Haugland, J. M., Jorgensen, C. R., Leonard, A. D., Kanter, M. C., Solomon, D. H., Zabalgoitia, M., Mego, D., Carter, J. E., Boyd, S. Y., Boop, B. S., LaLonde, D., Modlin, R., Logan, W. R., Green, B. J., Hamilton, W. P., Mezei, L., Riggio, S., Feldman, G., Hayward, A., Strauss, R., Anderson, W., Grover, J., McKenzie, M., Hart-McArthur, P., Gramberg, M., Houston, H., Halperin, J. L., Rothauf, E. B., Weinberger, J. M., Goldman, M. E., Laupacis, A., Chan, K. L., Bourque, P., Biggs, J., Ives, A., Feinberg, W. M., Kern, K. B., Pennock, G. D., Fenster, P. E., Huerta, B. J., Ohm, J., Dittrich, H. C., Kerridge, C., Keen, W., Swenson, M., Kopecky, S. L., Litin, S. C., Wiebers, D. O., Holland, A. E., Brown, R. D., Khandheria, B. K., Meissner, I., Tucker, K. R., Rothbart, R., Torelli, J., Schmidt, J., Murray, D., Ruzich, R. S., Loutfi, H., Appleton, C., Ingall, T., Carlson, L., Wilson, D., Dunn, M., Nolte, B., Edwards, C., Dick, A., Price, L. A., Janosik, D. L., Bjerregaard, P., Quattromani, A., Schiller, L., Labovitz, A., Burch, C., Parks, B. J., Thompson, D., Berarducci, L., Carey, S., Vigil, A., Falk, R., Battinelli, N., McNeil, M., Davidoff, R., Bernard, S., Bergethon, P., Fiori, L., Albers, G., Atwood, E., Clark, J., Tong, D., Yenari, M., Froelicker, V., Lutsep, H., Hock, N. H., Quaglietti, S., Kemp, S., Alpert, M. A., Rothrock, J. F., Hupp, C. H., Massey, C. V., Hamilton, W. J., Miller, V. T., Fox, J., Kronmal, R. A., McBride, R., Nasco, E., Pearce, L. A., Fletcher, K., Koehler, J., Hart, R. G., Sherman, D. G., Talbert, R. L., Heberling, P. A., Kajzer, C., Bovill, E., Geffken, D., Cornell, E., Nightingale, S., Blackshear, J. L., Halperin, J. L., Hart, R. G., Laupacis, A., McAnulty, J. H., McBride, R., Kelsy, S. P., Levy, D. E., Marsh, J. D., Welch, K. M. A., Marler, J. R. & Walker, M. D., Sep 7 1996, In : Lancet. 348, 9028, p. 633-638 6 p.

Research output: Contribution to journalArticle

1063 Scopus citations

A double-blind placebo-controlled clinical evaluation of MultiStem for the treatment of ischemic stroke

Hess, D. C., Sila, C. A., Furlan, A. J., Wechsler, L. R., Switzer, J. A. & Mays, R. W., Apr 2014, In : International Journal of Stroke. 9, 3, p. 381-386 6 p.

Research output: Contribution to journalArticle

62 Scopus citations

A multicentre, randomised, sham-controlled trial on REmote iSchemic conditioning In patients with acute STroke (RESIST) – Rationale and study design

Blauenfeldt, R. A., Hjort, N., Gude, M. F., Behrndtz, A. B., Fisher, M., Valentin, J. B., Kirkegaard, H., Johnsen, S. P., Hess, D. C. & Andersen, G., Mar 1 2020, In : European Stroke Journal. 5, 1, p. 94-101 8 p.

Research output: Contribution to journalArticle

Open Access

An analysis of business issues in a telestroke project

Cho, S., Khasanshina, E. V., Mathiassen, L., Hess, D. C., Wang, S. & Stachura, M. E., Jul 1 2007, In : Journal of Telemedicine and Telecare. 13, 5, p. 257-262 6 p.

Research output: Contribution to journalArticle

16 Scopus citations

Anomaly in aortic arch alters pathological outcome of transient global ischemia in Rhesus macaques

Hara, K., Yasuhara, T., Maki, M., Matsukawa, N., Yu, G., Xu, L., Tambrallo, L., Rodriguez, N. A., Stern, D. M., Yamashima, T., Buccafusco, J. J., Kawase, T., Hess, D. C. & Borlongan, C. V., Aug 25 2009, In : Brain Research. 1286, p. 185-191 7 p.

Research output: Contribution to journalArticle

5 Scopus citations

Anticardiolipin antibodies: A study of frequency in TIA and stroke

Hess, D. C., Krauss, J., Adams, R. J., Nichols, F. T., Zhang, D. I. & Rountree, H. A., Apr 1991, In : Neurology. 41, 4, p. 525-528 4 p.

Research output: Contribution to journalArticle

58 Scopus citations

Antiphospholipid antibodies in stroke.

Hess, D. C., Adams, R. J. & Nichols, F. T., Dec 1 1989, In : Journal of the Medical Association of Georgia. 78, 12, p. 815-820 6 p.

Research output: Contribution to journalArticle

Antiphospholipid antibody syndrome mimicking multiple sclerosis clinically and by magnetic resonance imaging

Scott, T. F., Hess, D. & Brillman, J., Apr 25 1994, In : Archives of Internal Medicine. 154, 8, p. 917-920 4 p.

Research output: Contribution to journalArticle

52 Scopus citations

A simple, assumption-free, and clinically interpretable approach for analysis of modified Rankin outcomes

Howard, G., Waller, J. L., Voeks, J. H., Howard, V. J., Jauch, E. C., Lees, K. R., Nichols, F. T., Rahlfs, V. W. & Hess, D. C., Mar 1 2012, In : Stroke. 43, 3, p. 664-669 6 p.

Research output: Contribution to journalArticle

48 Scopus citations

A telestroke network enhances recruitment into acute stroke clinical trials

Switzer, J. A., Hall, C. E., Close, B., Nichols, F. T., Gross, H., Bruno, A. & Hess, D. C., Mar 1 2010, In : Stroke. 41, 3, p. 566-569 4 p.

Research output: Contribution to journalArticle

41 Scopus citations
76 Scopus citations

Behavioral and histological characterization of intrahippocampal grafts of human bone marrow-derived multipotent progenitor cells in neonatal rats with hypoxic-ischemic injury

Yasuhara, T., Matsukawa, N., Yu, G., Xu, L., Mays, R. W., Kovach, J., Deans, R. J., Hess, D. C., Carroll, J. E. & Borlongan, C. V., May 22 2006, In : Cell Transplantation. 15, 3, p. 231-238 8 p.

Research output: Contribution to journalArticle

81 Scopus citations

Bone marrow as a source of endothelial cells and NeuN-expressing cells after stroke

Hess, D. C., Hill, W. D., Martin-Studdard, A., Carroll, J., Brailer, J. & Carothers, J., May 27 2002, In : Stroke. 33, 5, p. 1362-1368 7 p.

Research output: Contribution to journalArticle

243 Scopus citations

Bone marrow grafts restore cerebral blood flow and blood brain barrier in stroke rats

Borlongan, C. V., Lind, J. G., Dillon-Carter, O., Yu, G., Hadman, M., Cheng, C., Carroll, J. & Hess, D. C., Jun 4 2004, In : Brain Research. 1010, 1-2, p. 108-116 9 p.

Research output: Contribution to journalArticle

144 Scopus citations

BrdU-positive cells in the neonatal mouse hippocampus following hypoxic-ischemic brain injury

Bartley, J., Soltau, T., Wimborne, H., Kim, S., Martin-Studdard, A., Hess, D. C., Hill, W. D., Waller, J. L. & Carroll, J. E., Mar 2 2005, In : BMC Neuroscience. 6, 15.

Research output: Contribution to journalArticle

50 Scopus citations

Carotid endarterectomy - An evidence-based review: Report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology

Chaturvedi, S., Bruno, A., Feasby, T., Holloway, R., Benavente, O., Cohen, S. N., Cote, R., Hess, D., Saver, J., Spence, J. D., Stern, B. & Wilterdink, J., Sep 27 2005, In : Neurology. 65, 6, p. 794-801 8 p.

Research output: Contribution to journalArticle

401 Scopus citations

Carotid endarterectomy - An evidence-based review: Report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology

Chaturvedi, S., Bruno, A., Feasby, T., Holloway, R., Benavente, O., Cohen, S. N., Cote, R., Hess, D., Saver, J., Spence, J. D., Stern, B. & Wilterdink, J., Feb 1 2008, In : CONTINUUM Lifelong Learning in Neurology. 14, 1, p. 197-204 8 p.

Research output: Contribution to journalArticle

Cell therapy for ischaemic stroke

Hess, D. C. & Hill, W. D., Apr 1 2011, In : Cell Proliferation. 44, SUPPL. 1, p. 1-8 8 p.

Research output: Contribution to journalArticle

12 Scopus citations

Cerebral lupus vasculopathy: Mechanisms and clinical relevance

Hess, D. C., Jan 1 1997, In : Annals of the New York Academy of Sciences. 823, p. 154-168 15 p.

Research output: Contribution to journalArticle

44 Scopus citations

Chronic Remote Ischemic Conditioning Is Cerebroprotective and Induces Vascular Remodeling in a VCID Model

Khan, M. B., Hafez, S., Hoda, M. N., Baban, B., Wagner, J., Awad, M. E., Sangabathula, H., Haigh, S., Elsalanty, M., Waller, J. L. & Hess, D. C., Feb 1 2018, In : Translational Stroke Research. 9, 1, p. 51-63 13 p.

Research output: Contribution to journalArticle

9 Scopus citations

Clinical, radiological, and pathological aspects of cerebrovascular disease associated with antiphospholipid antibodies

Kittner, S., Joseph, C., Levine, S. R., Sawaya, K., Palm, L., Carey, J., Deegan, M., Brey, R., Davis, W., Kaste, J., McGlasson, D., McAtee, R., Feldmann, E., Friedberg, K., Stem, B., Karanjia, P., Jacobson, D., Lobner, S., Hess, D., Adams, R. & 20 others, Weinberger, J., Dunn, M., Horowitz, D., Tuhrim, S., Fayad, P., Brass, L. M., Hwang, T. L., Trijillano, A., Babikian, V., Hersey, H., Sloan, M., Fetzer, D. E., Coull, B., Briley, D., deGarmo, P., Gomez, C., Jedlicka, M., Fisher, M., Doyle, E. & DeWitt, D. D., Dec 1993, In : Stroke. 24, 12, p. I-120-I-123

Research output: Contribution to journalArticle

23 Scopus citations

Clinical and laboratory findings in patients with antiphospholipid antibodies and cerebral ischemia

The Antiphospholipid Antibodies in Stroke Study Group, Sep 1990, In : Stroke. 21, 9, p. 1268-1273 6 p.

Research output: Contribution to journalArticle

173 Scopus citations

Cognitive and neurologic deficits in the MRL/lpr mouse: A clinicopathologic study

Hess, D. C., Taormina, M., Thompson, J., Sethi, K. D., Diamond, B., Rao, R., Chamberlain, C. R. & Feldman, D. S., Jan 1 1993, In : Journal of Rheumatology. 20, 4, p. 610-617 8 p.

Research output: Contribution to journalArticle

83 Scopus citations

Collaterals 2016: Translating the collaterome around the globe

for the Collaterals 2016 Consortium, Jan 1 2017, In : International Journal of Stroke. 12, 4, p. 338-342 5 p.

Research output: Contribution to journalArticle

3 Scopus citations

Combined cyclosporine-A and methylprednisolone treatment exerts partial and transient neuroprotection against ischemic stroke

Yu, G., Hess, D. C. & Borlongan, C. V., Aug 20 2004, In : Brain Research. 1018, 1, p. 32-37 6 p.

Research output: Contribution to journalArticle

29 Scopus citations

Comparative Neuroimaging With Pathologic Correlates in Alexander's Disease

Hess, D. C., Fischer, A. Q., Yaghmai, F., Figueroa Ortiz, R. E. & Akamatsu, Y., Jan 1 1990, In : Journal of Child Neurology. 5, 3, p. 248-252 5 p.

Research output: Contribution to journalArticle

15 Scopus citations

Creutzfeldt‐Jakob's disease presenting with ataxia and a movement disorder

Sethi, K. D. & Hess, D. C., Jan 1 1991, In : Movement Disorders. 6, 2, p. 157-162 6 p.

Research output: Contribution to journalArticle

12 Scopus citations

Delayed minocycline inhibits ischemia-activated matrix metalloproteinases 2 and 9 after experimental stroke

Machado, L. S., Kozak, A., Ergul, A., Hess, D. C., Borlongan, C. V. & Fagan, S. C., Jul 17 2006, In : BMC Neuroscience. 7, 56.

Research output: Contribution to journalArticle

153 Scopus citations

Design and baseline characteristics of the Stroke Prevention by Aggressive Reduction in Cholesterol Levels (SPARCL) Study

Sillesen, H., Albers, G., Altafullah, I., Benavente, O., Book, D., Broderick, J., Calder, C., Callahan, A. S., Carlini, W., Chaturvedi, S., Chippendale, T., Clark, W., Collins, G., Coull, B., Davis, P., Devlin, T., Dick, A. R., Dirr-Ledbetter, L. Y., Dooneief, G., Duff, R. S. & 124 others, Estronza, N., Forteza, A., Frankel, M. R., Frey, J. L., Friday, G., Goldstein, J., Goldstein, S., Graham, G., Harper, W., Harris, J., Hendin, B., Hess, D. C., Hinton, R., Hollander, J., Hsu, C. Y., Hughes, R. L., Kasner, S., Kent, T. A., Kim, L., Kirshner, H., LaMonte, M., Levin, K., Libman, R., McDowell, P., McGee, F. E., Meyer, B., Minagar, A., Munschauer, F. E., Munson, R., Nash, M., Orr, S. C., Ratinov, G., Salanga, V., Sen, S., Silliman, S., Singer, R., Smith, D., Sullivan, H., Thaler, D., Tietjen, G., Tuchman, M., Uskavitch, D., Verro, P., Vicari, R., Weinstein, R., Wilterdink, J., Zweifler, R., Beaudry, M., Cote, R., Hoyte, K., Lebrun, L. H., Norris, J., Selchen, D., Shuaib, A., Simard, D., Spence, D., Teal, P., Winger, M., Schmidt, R., Pramsohler, B., Schmidauer, C., Kaste, M., Sivenius, J., Wagner, A., Terent, A., Amarenco, P., Milandre, L., Chollet, F., de Broucker, T., Moulin, T., Roullet, E., Leys, D., Mahagne, M. H., Hennerici, M., Heiss, W. D., Busse, O., Haberl, R., Harms, L., Diener, C., Hamann, G., Ringelstein, E. B., Canal, N., Capurso, A., Mamoli, A., Frattola, L., Gandolfo, C., Senin, U., Zito, M., de Keyser, K., Netherlands, T., Koudstaal, P. J., Haas, J. A., de Jong, G., Bogousslavsky, J., Mattie, H., Baumgartner, R., MacWalter, R. S., Dijkhuizen, R., Ekpo, E. B., Bath, P., Lees, K. R., Ferro, J., Cunha, L., Davalos, A., Chamorro, A., Sabin, A., Jimenez, D., Gonzalez, J. R., Lago, A., Egido, J., Vivancos, J., Guiu, M., Dorman, G., Davis, S., Gilles, D., Frayne, J., Crimmins, D., Dimmit, S., Singh, G. P., Scott, R., Anderson, N. E., Carr, J., Kruger, A. K. & Gardiner, J., Jan 1 2003, In : Cerebrovascular Diseases. 16, 4, p. 389-395 7 p.

Research output: Contribution to journalArticle

156 Scopus citations

Development and characterization of a Yucatan miniature biomedical pig permanent middle cerebral artery occlusion stroke model

Platt, S. R., Holmes, S. P., Howerth, E. W., Duberstein, K. J. J., Dove, C. R., Kinder, H. A., Wyatt, E. L., Linville, A. V., Lau, V. W., Stice, S. L., Hill, W. D., Hess, D. C. & West, F. D., Mar 23 2014, In : Experimental and Translational Stroke Medicine. 6, 1, 5.

Research output: Contribution to journalArticle

24 Scopus citations

Development of an allogeneic adherent stem cell therapy for treatment of ischemic stroke

Mays, R. W., Borlongan, C. V., Yasuhara, T., Hara, K., Maki, M., Carroll, J. E., Deans, R. J. & Hess, D. C., 2010, In : Journal of Experimental Stroke and Translational Medicine. 3, 1, p. 34-46 13 p.

Research output: Contribution to journalArticle

28 Scopus citations
15 Scopus citations

Epilepsia partialis continua in multiple sclerosis

Hess, D. C. & Sethi, K. D., Jan 1 1990, In : International Journal of Neuroscience. 50, 1-2, p. 109-111 3 p.

Research output: Contribution to journalArticle

14 Scopus citations

E-Selectin expression on human brain microvascular endothelial cells

Hess, D. C., Thompson, Y., Sprinkle, A., Carroll, J. & Smith, J., Jul 26 1996, In : Neuroscience Letters. 213, 1, p. 37-40 4 p.

Research output: Contribution to journalArticle

26 Scopus citations

Establishing data elements for the Paul Coverdell National Acute Stroke Registry: Part 1: Proceedings of an expert panel

Wattigney, W. A., Croft, J. B., Mensah, G. A., Alberts, M. J., Shephard, T. J., Gorelick, P. B., Nilasena, D. S., Hess, D. C., Walker, M. D., Hanley, D. F., Shwayder, P., Girgus, M., Neff, L. J., Williams, J. E., LaBarthe, D. R. & Collins, J. L., Jan 1 2003, In : Stroke. 34, 1, p. 151-156 6 p.

Research output: Contribution to journalArticle

56 Scopus citations

Establishment of an internationally agreed minimum data set for acute telestroke

Cadilhac, D. A., Bagot, K. L., Demaerschalk, B. M., Hubert, G., Schwamm, L., Watkins, C. L., Lightbody, C. E., Kim, J., Vu, M., Pompeani, N., Switzer, J., Caudill, J., Estrada, J., Viswanathan, A., Hubert, N., Ohannessian, R., Hargroves, D., Roberts, N., Ingall, T., Hess, D. C. & 3 others, Ranta, A., Padma, V. & Bladin, C. F., Jan 1 2020, (Accepted/In press) In : Journal of Telemedicine and Telecare.

Research output: Contribution to journalArticle

1 Scopus citations

Evaluating the comatose patient: Rapid neurologic assessment is key to appropriate management

Malik, K. & Hess, D. C., Jan 1 2002, In : Postgraduate medicine. 111, 2, p. 38-55 18 p.

Research output: Contribution to journalArticle

12 Scopus citations

Expansion of telestroke services improves quality of care provided in super rural areas

Zhang, D., Wang, G., Zhu, W., Thapa, J. R., Switzer, J. A., Hess, D. C., Smith, M. L. & Ritchey, M. D., Dec 2018, In : Health Affairs. 37, 12, p. 2005-2013 9 p.

Research output: Contribution to journalArticle

5 Scopus citations

Gait analysis in a pre- and post-ischemic stroke biomedical pig model

Duberstein, K. J., Platt, S. R., Holmes, S. P., Dove, C. R., Howerth, E. W., Kent, M., Stice, S. L., Hill, W. D., Hess, D. C. & West, F. D., Feb 10 2014, In : Physiology and Behavior. 125, p. 8-16 9 p.

Research output: Contribution to journalArticle

22 Scopus citations

Gaze‐evoked involuntary movement

Sethi, K. D., Hess, D. C., Harbour, R. C. & Holmes, G. L., 1990, In : Movement Disorders. 5, 2, p. 139-142 4 p.

Research output: Contribution to journalArticle

7 Scopus citations

Hematopoietic origin of glomerular mesangial cells

Masuya, M., Drake, C. J., Fleming, P. A., Reilly, C. M., Zeng, H., Hill, W. D., Martin-Studdard, A., Hess, D. C. & Ogawa, M., Mar 15 2003, In : Blood. 101, 6, p. 2215-2218 4 p.

Research output: Contribution to journalArticle

159 Scopus citations

Hematopoietic origin of microglial and perivascular cells in brain

Hess, D. C., Abe, T., Hill, W. D., Studdard, A. M., Carothers, J., Masuya, M., Fleming, P. A., Drake, C. J. & Ogawa, M., Apr 1 2004, In : Experimental Neurology. 186, 2, p. 134-144 11 p.

Research output: Contribution to journalArticle

219 Scopus citations

Hippocampal CA1 cell loss in a non-human primate model of transient global ischemia: A pilot study

Hara, K., Yasuhara, T., Matsukawa, N., Maki, M., Masuda, T., Yu, G., Xu, L., Tambrallo, L., Rodriguez, N. A., Stern, D. M., Kawase, T., Yamashima, T., Buccafusco, J. J., Hess, D. C. & Borlongan, C. V., Sep 14 2007, In : Brain Research Bulletin. 74, 1-3, p. 164-171 8 p.

Research output: Contribution to journalArticle

17 Scopus citations

Human neural stem cell extracellular vesicles improve recovery in a porcine model of ischemic stroke

Webb, R. L., Kaiser, E. E., Jurgielewicz, B. J., Spellicy, S., Scoville, S. L., Thompson, T. A., Swetenburg, R. L., Hess, D. C., West, F. D. & Stice, S. L., Jan 1 2018, In : Stroke. 49, 5, p. 1248-1256 9 p.

Research output: Contribution to journalArticle

Open Access
39 Scopus citations

Human Neural Stem Cell Extracellular Vesicles Improve Tissue and Functional Recovery in the Murine Thromboembolic Stroke Model

Webb, R. L., Kaiser, E. E., Scoville, S. L., Thompson, T. A., Fatima, S., Pandya, C., Sriram, K., Swetenburg, R. L., Vaibhav, K., Arbab, A. S., Baban, B., Dhandapani, K. M., Hess, D. C., Hoda, M. N. & Stice, S. L., Oct 1 2018, In : Translational Stroke Research. 9, 5, p. 530-539 10 p.

Research output: Contribution to journalArticle

33 Scopus citations