David C Hess

EVP, Med Affairs & Dean, MCG

  • 10585 Citations
  • 57 h-Index
1989 …2019
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Research Output 1989 2019

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Article
2008
95 Citations (Scopus)

Intravenous grafts recapitulate the neurorestoration afforded by intracerebrally delivered multipotent adult progenitor cells in neonatal hypoxic-ischemic rats

Yasuhara, T., Hara, K., Maki, M., Mays, R. W., Deans, R. J., Hess, D. C., Carroll, J. E. & Borlongan, C. V., Nov 1 2008, In : Journal of Cerebral Blood Flow and Metabolism. 28, 11, p. 1804-1810 7 p.

Research output: Contribution to journalArticle

Stem Cells
Transplants
Transplantation
Wounds and Injuries
Cell- and Tissue-Based Therapy
1 Citation (Scopus)
Geography
Fibrinolytic Agents
Tissue Plasminogen Activator
Rural Population
Neurology
171 Citations (Scopus)

Stem cells and neurological diseases

Hess, D. C. & Borlongan, C. V., Feb 1 2008, In : Cell Proliferation. 41, S1, p. 94-114 21 p.

Research output: Contribution to journalArticle

Stem Cells
Cell- and Tissue-Based Therapy
Neural Stem Cells
Brain-Derived Neurotrophic Factor
Brain
2007
16 Citations (Scopus)

An analysis of business issues in a telestroke project

Cho, S., Khasanshina, E. V., Mathiassen, L., Hess, D. C., Wang, S. & Stachura, M. E., Jul 1 2007, In : Journal of Telemedicine and Telecare. 13, 5, p. 257-262 6 p.

Research output: Contribution to journalArticle

Rural Hospitals
Telemedicine
Negotiating
Tissue Plasminogen Activator
Stroke
15 Citations (Scopus)

Hippocampal CA1 cell loss in a non-human primate model of transient global ischemia: A pilot study

Hara, K., Yasuhara, T., Matsukawa, N., Maki, M., Masuda, T., Yu, G., Xu, L., Tambrallo, L., Rodriguez, N. A., Stern, D. M., Kawase, T., Yamashima, T., Buccafusco, J. J., Hess, D. C. & Borlongan, C. V., Sep 14 2007, In : Brain Research Bulletin. 74, 1-3, p. 164-171 8 p.

Research output: Contribution to journalArticle

Primates
Ischemia
Calpain
Hippocampus
Cathepsins
91 Citations (Scopus)

Transplantation of bone marrow-derived stem cells: A promising therapy for stroke

Tang, Y., Yasuhara, T., Hara, K., Matsukawa, N., Maki, M., Yu, G., Xu, L., Hess, D. C. & Borlongan, C. V., May 4 2007, In : Cell Transplantation. 16, 2, p. 159-169 11 p.

Research output: Contribution to journalArticle

Stem cells
Bone Marrow Transplantation
Bone
Stem Cells
Stroke
33 Citations (Scopus)

Transplantation of post-mitotic human neuroteratocarcinoma-overexpressing Nurr1 cells provides therapeutic benefits in experimental stroke: In vitro evidence of expedited neuronal differentiation and GDNF secretion

Hara, K., Matsukawa, N., Yasuhara, T., Xu, L., Yu, G., Maki, M., Kawase, T., Hess, D. C., Kim, S. U. & Borlongan, C. V., May 1 2007, In : Journal of Neuroscience Research. 85, 6, p. 1240-1251 12 p.

Research output: Contribution to journalArticle

Glial Cell Line-Derived Neurotrophic Factor
Transplantation
Stroke
Therapeutics
Nestin
2006
80 Citations (Scopus)

Behavioral and histological characterization of intrahippocampal grafts of human bone marrow-derived multipotent progenitor cells in neonatal rats with hypoxic-ischemic injury

Yasuhara, T., Matsukawa, N., Yu, G., Xu, L., Mays, R. W., Kovach, J., Deans, R. J., Hess, D. C., Carroll, J. E. & Borlongan, C. V., May 22 2006, In : Cell Transplantation. 15, 3, p. 231-238 8 p.

Research output: Contribution to journalArticle

Stem cells
Grafts
Rats
Bone
Stem Cells
149 Citations (Scopus)

Delayed minocycline inhibits ischemia-activated matrix metalloproteinases 2 and 9 after experimental stroke

Machado, L. S., Kozak, A., Ergul, A., Hess, D. C., Borlongan, C. V. & Fagan, S. C., Jul 17 2006, In : BMC Neuroscience. 7, 56.

Research output: Contribution to journalArticle

Minocycline
Matrix Metalloproteinase 2
Matrix Metalloproteinase 9
Matrix Metalloproteinases
Ischemia
53 Citations (Scopus)

Hypertension after experimental cerebral ischemia: Candesartan provides neurovascular protection

Fagan, S. C., Kozak, A., Hill, W. D., Pollock, D. M., Xu, L., Johnson, M. H., Ergul, A. & Hess, D. C., Mar 2006, In : Journal of hypertension. 24, 3, p. 535-539 5 p.

Research output: Contribution to journalArticle

Brain Ischemia
Blood Pressure
Hypertension
Reperfusion
Middle Cerebral Artery Infarction
98 Citations (Scopus)

Minocycline for short-term neuroprotection

Elewa, H. F., Hilali, R., Hess, D. C., Machado, L. S. & Fagan, S. C., Apr 1 2006, In : Pharmacotherapy. 26, 4, p. 515-521 7 p.

Research output: Contribution to journalArticle

Minocycline
Nervous System Trauma
Neuroprotective Agents
Infection
Tetracycline
56 Citations (Scopus)

Telestroke: Extending stroke expertise into underserved areas

Hess, D. C., Wang, S., Gross, H., Nichols, F. T., Hall, C. E. & Adams, R. J., Mar 1 2006, In : Lancet Neurology. 5, 3, p. 275-278 4 p.

Research output: Contribution to journalArticle

Stroke
Rural Hospitals
Community Hospital
Tissue Plasminogen Activator
Rural Population
27 Citations (Scopus)

Transplantation of Cryopreserved Human Bone Marrow-derived Multipotent Adult Progenitor Cells for Neonatal Hypoxic-Ischemic Injury: Targeting the Hippocampus

Yasuhara, T., Matsukawa, N., Yu, G., Xu, L., Mays, R. W., Kovach, J., Deans, R., Hess, D. C., Carroll, J. E. & Borlongan, C. V., Jan 1 2006, In : Reviews in the Neurosciences. 17, 1-2, p. 215-226 12 p.

Research output: Contribution to journalArticle

Hippocampus
Stem Cells
Transplantation
Bone Marrow
Wounds and Injuries
2005
23 Citations (Scopus)

Acute functional effects of cyclosporine-A and methylprednisolone treatment in adult rats exposed to transient ischemic stroke

Borlongan, C. V., Yu, G., Matsukawa, N., Xu, L., Hess, D. C., Sanberg, P. R. & Wang, Y., Feb 11 2005, In : Life sciences. 76, 13, p. 1503-1512 10 p.

Research output: Contribution to journalArticle

Methylprednisolone
Cyclosporine
Rats
Stroke
Animals
49 Citations (Scopus)

BrdU-positive cells in the neonatal mouse hippocampus following hypoxic-ischemic brain injury

Bartley, J., Soltau, T., Wimborne, H., Kim, S., Martin-Studdard, A., Hess, D. C., Hill, W. D., Waller, J. L. & Carroll, J. E., Mar 2 2005, In : BMC Neuroscience. 6, 15.

Research output: Contribution to journalArticle

Bromodeoxyuridine
Brain Injuries
Hippocampus
Neurogenesis
Dentate Gyrus
390 Citations (Scopus)

Carotid endarterectomy - An evidence-based review: Report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology

Chaturvedi, S., Bruno, A., Feasby, T., Holloway, R., Benavente, O., Cohen, S. N., Cote, R., Hess, D. C., Saver, J., Spence, J. D., Stern, B. & Wilterdink, J., Sep 27 2005, In : Neurology. 65, 6, p. 794-801 8 p.

Research output: Contribution to journalArticle

Biomedical Technology Assessment
Carotid Endarterectomy
Pathologic Constriction
Endarterectomy
Stroke
37 Citations (Scopus)

Limitations of intravenous human bone marrow CD133+ cell grafts in stroke rats

Borlongan, C. V., Evans, A., Yu, G. & Hess, D. C., Jun 28 2005, In : Brain Research. 1048, 1-2, p. 116-122 7 p.

Research output: Contribution to journalArticle

Bone Marrow Cells
Transplantation
Stroke
Transplants
Graft Survival
127 Citations (Scopus)

REACH: Clinical feasibility of a rural telestroke network

Hess, D. C., Wang, S., Hamilton, W. B., Lee, S., Pardue, C., Waller, J. L., Gross, H., Nichols, F. T., Hall, C. & Adams, R. J., Sep 1 2005, In : Stroke. 36, 9, p. 2018-2020 3 p.

Research output: Contribution to journalArticle

Stroke
Tissue Plasminogen Activator
Rural Hospitals
Community Hospital
National Institutes of Health (U.S.)
107 Citations (Scopus)

The neuroblast and angioblast chemotaxic factor SDF-1 (CXCL12) expression is briefly up regulated by reactive astrocytes in brain following neonatal hypoxic-ischemic injury

Miller, J. T., Bartley, J. H., Wimborne, H. J. C., Walker, A. L., Hess, D. C., Hill, W. D. & Carroll, J. E., Oct 31 2005, In : BMC Neuroscience. 6, 63.

Research output: Contribution to journalArticle

Astrocytes
Wounds and Injuries
Brain
Blood Vessels
Bone Marrow Cells
2004
140 Citations (Scopus)

Bone marrow grafts restore cerebral blood flow and blood brain barrier in stroke rats

Borlongan, C. V., Lind, J. G., Dillon-Carter, O., Yu, G., Hadman, M., Cheng, C., Carroll, J. E. & Hess, D. C., Jun 4 2004, In : Brain Research. 1010, 1-2, p. 108-116 9 p.

Research output: Contribution to journalArticle

Cerebrovascular Circulation
Blood-Brain Barrier
Mesenchymal Stromal Cells
Middle Cerebral Artery Infarction
Bone Marrow
27 Citations (Scopus)

Combined cyclosporine-A and methylprednisolone treatment exerts partial and transient neuroprotection against ischemic stroke

Yu, G., Hess, D. C. & Borlongan, C. V., Aug 20 2004, In : Brain Research. 1018, 1, p. 32-37 6 p.

Research output: Contribution to journalArticle

Methylprednisolone
Cyclosporine
Stroke
Neuroprotection
Middle Cerebral Artery Infarction
214 Citations (Scopus)

Hematopoietic origin of microglial and perivascular cells in brain

Hess, D. C., Abe, T., Hill, W. D., Studdard, A. M., Carothers, J., Masuya, M., Fleming, P. A., Drake, C. J. & Ogawa, M., Apr 1 2004, In : Experimental Neurology. 186, 2, p. 134-144 11 p.

Research output: Contribution to journalArticle

Brain
Middle Cerebral Artery Infarction
Stem Cells
Endothelial Cells
Hematopoietic Stem Cells
15 Citations (Scopus)

Intracerebral transplantation of carotid body in rats with transient middle cerebral artery occlusion

Yu, G., Xu, L., Hadman, M., Hess, D. C. & Borlongan, C. V., Jul 23 2004, In : Brain Research. 1015, 1-2, p. 50-56 7 p.

Research output: Contribution to journalArticle

Carotid Body
Middle Cerebral Artery Infarction
Transplantation
Stroke
Nerve Growth Factors
38 Citations (Scopus)

Intracerebral xenografts of mouse bone marrow cells in adult rats facilitate restoration of cerebral blood flow and blood-brain barrier

Borlongan, C. V., Lind, J. G., Dillon-Carter, O., Yu, G., Hadman, M., Cheng, C., Carroll, J. E. & Hess, D. C., May 29 2004, In : Brain Research. 1009, 1-2, p. 26-33 8 p.

Research output: Contribution to journalArticle

Cerebrovascular Circulation
Blood-Brain Barrier
Heterografts
Bone Marrow Cells
Transplantation
49 Citations (Scopus)

Intracerebral Xenotransplantation of GFP Mouse Bone Marrow Stromal Cells in Intact and Stroke Rat Brain: Graft Survival and Immunologic Response

Irons, H., Lind, J. G., Wakade, C. G., Yu, G., Hadman, M., Carroll, J. E., Hess, D. C. & Borlongan, C. V., Jan 1 2004, In : Cell Transplantation. 13, 3, p. 283-294 12 p.

Research output: Contribution to journalArticle

Heterologous Transplantation
Graft Survival
Green Fluorescent Proteins
Mesenchymal Stromal Cells
Grafts
125 Citations (Scopus)

Low dose intravenous minocycline is neuroprotective after middle cerebral artery occlusion-reperfusion in rats

Xu, L., Fagan, S. C., Waller, J. L., Edwards, D., Borlongan, C. V., Zheng, J., Hill, W. D., Feurstein, G. & Hess, D. C., Apr 26 2004, In : BMC Neurology. 4, 7.

Research output: Contribution to journalArticle

Minocycline
Middle Cerebral Artery Infarction
Reperfusion
Hemodynamics
Neuroprotective Agents
215 Citations (Scopus)

Minocycline Up-regulates Bcl-2 and Protects against Cell Death in Mitochondria

Wang, J., Wei, Q., Wang, C. Y., Hill, W. D., Hess, D. C. & Dong, Z., May 7 2004, In : Journal of Biological Chemistry. 279, 19, p. 19948-19954 7 p.

Research output: Contribution to journalArticle

Minocycline
Mitochondria
Cell death
Cell Death
Up-Regulation
106 Citations (Scopus)

Optimal delivery of minocycline to the brain: Implication for human studies of acute neuroprotection

Fagan, S. C., Edwards, D. J., Borlongan, C. V., Xu, L., Arora, A., Feuerstein, G. & Hess, D. C., Apr 1 2004, In : Experimental Neurology. 186, 2, p. 248-251 4 p.

Research output: Contribution to journalArticle

Minocycline
Brain
Brain Diseases
Neuroprotective Agents
Brain Injuries
91 Citations (Scopus)

Remote evaluation of acute ischemic stroke in rural community hospitals in Georgia

Wang, S., Gross, H., Lee, S. B., Pardue, C., Waller, J. L., Nichols, F. T., Adams, R. J. & Hess, D. C., Jul 1 2004, In : Stroke. 35, 7, p. 1763-1768 6 p.

Research output: Contribution to journalArticle

Rural Hospitals
Community Hospital
Rural Population
Stroke
National Institutes of Health (U.S.)
313 Citations (Scopus)

SDF-1 (CXCL12) Is Upregulated in the Ischemic Penumbra Following Stroke: Association with Bone Marrow Cell Homing to Injury

Hill, W. D., Hess, D. C., Martin-Studdard, A., Carothers, J. J., Zheng, J., Hale, D., Maeda, M., Fagan, S. C., Carroll, J. E. & Conway, S. J., Jan 1 2004, In : Journal of neuropathology and experimental neurology. 63, 1, p. 84-96 13 p.

Research output: Contribution to journalArticle

Bone Marrow Cells
Green Fluorescent Proteins
Stroke
Wounds and Injuries
Middle Cerebral Artery Infarction
8 Citations (Scopus)

Tracking Trends in Secondary Stroke Prevention Strategies

Carswell, J. L., Beard, K. A., Chevrette, M. M., Pardue, C. N., Hess, D. C. & Fagan, S. C., Feb 1 2004, In : Annals of Pharmacotherapy. 38, 2, p. 215-219 5 p.

Research output: Contribution to journalArticle

Secondary Prevention
Stroke
clopidogrel
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Medication Adherence
2003
155 Citations (Scopus)

Design and baseline characteristics of the Stroke Prevention by Aggressive Reduction in Cholesterol Levels (SPARCL) Study

Sillesen, H., Albers, G., Altafullah, I., Benavente, O., Book, D., Broderick, J., Calder, C., Callahan, A. S., Carlini, W., Chaturvedi, S., Chippendale, T., Clark, W., Collins, G., Coull, B., Davis, P., Devlin, T., Dick, A. R., Dirr-Ledbetter, L. Y., Dooneief, G., Duff, R. S. & 124 others, Estronza, N., Forteza, A., Frankel, M. R., Frey, J. L., Friday, G., Goldstein, J., Goldstein, S., Graham, G., Harper, W., Harris, J., Hendin, B., Hess, D. C., Hinton, R., Hollander, J., Hsu, C. Y., Hughes, R. L., Kasner, S., Kent, T. A., Kim, L., Kirshner, H., LaMonte, M., Levin, K., Libman, R., McDowell, P., McGee, F. E., Meyer, B., Minagar, A., Munschauer, F. E., Munson, R., Nash, M., Orr, S. C., Ratinov, G., Salanga, V., Sen, S., Silliman, S., Singer, R., Smith, D., Sullivan, H., Thaler, D., Tietjen, G., Tuchman, M., Uskavitch, D., Verro, P., Vicari, R., Weinstein, R., Wilterdink, J., Zweifler, R., Beaudry, M., Cote, R., Hoyte, K., Lebrun, L. H., Norris, J., Selchen, D., Shuaib, A., Simard, D., Spence, D., Teal, P., Winger, M., Schmidt, R., Pramsohler, B., Schmidauer, C., Kaste, M., Sivenius, J., Wagner, A., Terent, A., Amarenco, P., Milandre, L., Chollet, F., de Broucker, T., Moulin, T., Roullet, E., Leys, D., Mahagne, M. H., Hennerici, M., Heiss, W. D., Busse, O., Haberl, R., Harms, L., Diener, C., Hamann, G., Ringelstein, E. B., Canal, N., Capurso, A., Mamoli, A., Frattola, L., Gandolfo, C., Senin, U., Zito, M., de Keyser, K., Netherlands, T., Koudstaal, P. J., Haas, J. A., de Jong, G., Bogousslavsky, J., Mattie, H., Baumgartner, R., MacWalter, R. S., Dijkhuizen, R., Ekpo, E. B., Bath, P., Lees, K. R., Ferro, J., Cunha, L., Davalos, A., Chamorro, A., Sabin, A., Jimenez, D., Gonzalez, J. R., Lago, A., Egido, J., Vivancos, J., Guiu, M., Dorman, G., Davis, S., Gilles, D., Frayne, J., Crimmins, D., Dimmit, S., Singh, G. P., Scott, R., Anderson, N. E., Carr, J., Kruger, A. K. & Gardiner, J., Jan 1 2003, In : Cerebrovascular Diseases. 16, 4, p. 389-395 7 p.

Research output: Contribution to journalArticle

Stroke
Cholesterol
Coronary Disease
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Cerebrovascular Disorders
55 Citations (Scopus)

Establishing data elements for the Paul Coverdell National Acute Stroke Registry: Part 1: Proceedings of an expert panel

Wattigney, W. A., Croft, J. B., Mensah, G. A., Alberts, M. J., Shephard, T. J., Gorelick, P. B., Nilasena, D. S., Hess, D. C., Walker, M. D., Hanley, D. F., Shwayder, P., Girgus, M., Neff, L. J., Williams, J. E., LaBarthe, D. R. & Collins, J. L., Jan 1 2003, In : Stroke. 34, 1, p. 151-156 6 p.

Research output: Contribution to journalArticle

Registries
Stroke
Quality Improvement
Nonprofit Organizations
Professional Education
158 Citations (Scopus)

Hematopoietic origin of glomerular mesangial cells

Masuya, M., Drake, C. J., Fleming, P. A., Reilly, C. M., Zeng, H., Hill, W. D., Martin-Studdard, A., Hess, D. C. & Ogawa, M., Mar 15 2003, In : Blood. 101, 6, p. 2215-2218 4 p.

Research output: Contribution to journalArticle

Mesangial Cells
Bone Marrow Cells
Bone
Stem cells
Cells
144 Citations (Scopus)

Remote evaluation of acute ischemic stroke: reliability of National Institutes of Health Stroke Scale via telestroke.

Wang, S., Lee, S. B., Pardue, C., Ramsingh, D., Waller, J. L., Gross, H., Nichols, F. T., Hess, D. C. & Adams, R. J., Jan 1 2003, In : Stroke; a journal of cerebral circulation. 34, 10

Research output: Contribution to journalArticle

National Institutes of Health (U.S.)
Stroke
Drug Approval
Rural Hospitals
Community Hospital
2002
34 Citations (Scopus)

Acetoacetate increases expression of intercellular adhesion molecule-1 (ICAM-1) in human brain microvascular endothelial cells

Hoffman, W. H., Cheng, C., Passmore, G. G., Carroll, J. E. & Hess, D. C., Dec 13 2002, In : Neuroscience Letters. 334, 2, p. 71-74 4 p.

Research output: Contribution to journalArticle

Intercellular Adhesion Molecule-1
Ketone Bodies
Diabetic Ketoacidosis
Endothelial Cells
Brain
242 Citations (Scopus)

Bone marrow as a source of endothelial cells and NeuN-expressing cells after stroke

Hess, D. C., Hill, W. D., Martin-Studdard, A., Carroll, J., Brailer, J. & Carothers, J., May 27 2002, In : Stroke. 33, 5, p. 1362-1368 7 p.

Research output: Contribution to journalArticle

Bone Marrow Cells
Endothelial Cells
Bone Marrow
Stroke
Middle Cerebral Artery Infarction
12 Citations (Scopus)

Evaluating the comatose patient: Rapid neurologic assessment is key to appropriate management

Malik, K. & Hess, D. C., Jan 1 2002, In : Postgraduate medicine. 111, 2, p. 38-55 18 p.

Research output: Contribution to journalArticle

Coma
Nervous System
Pupil
Persistent Vegetative State
Light
5 Citations (Scopus)

Orthostatic paroxysmal dystonia

Sethi, K. D., Ki, H. L., Deuskar, V. & Hess, D. C., Jul 1 2002, In : Movement Disorders. 17, 4, p. 841-845 5 p.

Research output: Contribution to journalArticle

Dystonia
Internal Carotid Artery
Emission-Computed Tomography
Cerebrovascular Disorders
Posture
2001
27 Citations (Scopus)

Pharmacology and clinical experience with simvastatin

Hess, D. C. & Fagan, S. C., May 22 2001, In : Expert Opinion on Pharmacotherapy. 2, 1, p. 153-163 11 p.

Research output: Contribution to journalArticle

Simvastatin
Clinical Pharmacology
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Mortality
Coronary Disease
56 Citations (Scopus)

The NF-κB inhibitor diethyldithiocarbamate (DDTC) increases brain cell death in a transient middle cerebral artery occlusion model of ischemia

Hill, W. D., Hess, D. C., Carroll, J. E., Wakade, C. G., Howard, E. F., Chen, Q., Cheng, C., Martin-Studdard, A., Waller, J. L. & Beswick, R. A., Aug 20 2001, In : Brain Research Bulletin. 55, 3, p. 375-386 12 p.

Research output: Contribution to journalArticle

Ditiocarb
Brain Death
Middle Cerebral Artery Infarction
DNA Fragmentation
Cell Death
359 Citations (Scopus)

Use of anti-ICAM-1 therapy in ischemic stroke: Results of the enlimomab acute stroke trial

Sherman, D., Bes, A., Easton, J. D., Hacke, W., Kaste, M., Polmar, S. H., Zivin, J. A., Clark, W., Schneider, D., Whisnant, J., Fieschi, C., Miller, P., Schoenfeld, D., Street, J., Albers, G., Atkinson, R., Biller, J., Bruno, A., Carpenter, D., DeGraba, T. & 57 others, Driscoll, P., Ellis, J., Greenlee R., J., Hess, D. C., Horowitz, D. R., Davenport, J., Hsu, C., Starkman, S., Madden, K., Pettigrew, C., Rosenbaum, D., Schim, J., Tietjen, G., Mansbach, H., Edwards, K., Webb, R., Crisostomo, E., Wilterdrink, J., Rothrock, J., Zweifler, R., Dexter, J., Horowitz, S., Futrell, N., Alter, M., Ferbert, A., Prange, H., Wiersbitzky, M., Büttner, T., Schwartz, A., Busse, O., Klingelhöfer, J., Kaste, M., Erilä, T., Sivenius, J., Sotaniemi, K., Liukkonen, J., Hedman, C., Muuronen, A., Rissanen, A., Larrue, V., Blard, J. M., Caussanel, J. P., Feve, J. R., Moulin, T., Mahagne, M. H., Rancurel, G., Trouillas, P., Weber, M., Thomassen, L., Rosjø, Johnsen, H. J., Kjällman, L., Petersson, J., Ferrari, G., Lagi, A., Mamoli, A. & Re, G., Oct 23 2001, In : Neurology. 57, 8, p. 1428-1434 7 p.

Research output: Contribution to journalArticle

Intercellular Adhesion Molecule-1
Stroke
Placebos
Therapeutics
Fever
2000
39 Citations (Scopus)

Hypertonic mannitol loading of NF-κ̄ transcription factor decoys in human brain microvascular endothelial cells blocks upregulation of ICAM-1

Hess, D. C., Howard, E., Cheng, C., Carroll, J. & Hill, D. W., May 2000, In : Stroke. 31, 5, p. 1179-1186 8 p.

Research output: Contribution to journalArticle

Mannitol
Intercellular Adhesion Molecule-1
Transcription Factors
Up-Regulation
Endothelial Cells
2 Citations (Scopus)

Limb and hemispatial hypometria

Meador, K. J., Moore, E. E., Martin, R. C., Loring, D. W., Hess, D. C. & Heilman, K. M., Jan 1 2000, In : Journal of the International Neuropsychological Society. 6, 1, p. 71-75 5 p.

Research output: Contribution to journalArticle

Arm
Extremities
Hand
Patient Rights
Healthy Volunteers
1999
46 Citations (Scopus)

Is cholesterol a risk factor for stroke? Yes

Demchuk, A. M., Hess, D. C., Brass, L. M. & Yatsu, F. M., Jan 1 1999, In : Archives of Neurology. 56, 12, p. 1518-1520 3 p.

Research output: Contribution to journalArticle

Stroke
Cholesterol
1998
71 Citations (Scopus)

NF-κB is activated and ICAM-1 gene expression is upregulated during reoxygenation of human brain endothelial cells

Howard, E. F., Chen, Q., Cheng, C., Carroll, J. E. & Hess, D., Jun 5 1998, In : Neuroscience Letters. 248, 3, p. 199-203 5 p.

Research output: Contribution to journalArticle

NF-kappa B
Intercellular Adhesion Molecule-1
Endothelial Cells
Gene Expression
Brain
90 Citations (Scopus)

Nuclear factor-κB activation during cerebral reperfusion: Effect of attenuation with N-acetylcysteine treatment

Carroll, J. E., Howard, E. F., Hess, D. C., Wakade, C. G., Chen, Q. & Cheng, C., May 1 1998, In : Molecular Brain Research. 56, 1-2, p. 186-191 6 p.

Research output: Contribution to journalArticle

Acetylcysteine
Reperfusion
Cerebral Infarction
Middle Cerebral Artery Infarction
Infarction
1997
44 Citations (Scopus)

Cerebral lupus vasculopathy: Mechanisms and clinical relevance

Hess, D. C., Jan 1 1997, In : Annals of the New York Academy of Sciences. 823, p. 154-168 15 p.

Research output: Contribution to journalArticle

Brain
Endothelial cells
Endothelial Cells
Shwartzman Phenomenon
Chemical activation
1996
1057 Citations (Scopus)

Adjusted-dose warfarin versus low-intensity, fixed-dose warfarin plus aspirin for high-risk patients with atrial fibrillation: Stroke prevention in Atrial Fibrillation III Randomised Clinical Trial

Blackshear, J. L., Baker, V. S., Rubino, F., Safford, R., Lane, G., Flipse, T., Malouf, J., Thompson, R., Webel, R., Flaker, G. C., Young, L., Hess, D. C., Friedman, G., Burger, R., McAnulty, J. H., Coull, B. M., Marchant, C., Timberg, J., Janzik, C., Giraud, G. & 142 others, Halperin, B., Kron, J., Wynn, M., Raitt, M., Anderson, D. C., Asinger, R. W., Newburg, S. M., Fifield, J., Bundlie, S. R., Koller, R. L., Tarrel, R. D., Dick, C., Haugland, J. M., Jorgensen, C. R., Leonard, A. D., Kanter, M. C., Solomon, D. H., Zabalgoitia, M., Mego, D., Carter, J. E., Boyd, S. Y., Boop, B. S., LaLonde, D., Modlin, R., Logan, W. R., Green, B. J., Hamilton, W. P., Mezei, L., Riggio, S., Feldman, G., Hayward, A., Strauss, R., Anderson, W., Grover, J., McKenzie, M., Hart-McArthur, P., Gramberg, M., Houston, H., Halperin, J. L., Rothauf, E. B., Weinberger, J. M., Goldman, M. E., Laupacis, A., Chan, K. L., Bourque, P., Biggs, J., Ives, A., Feinberg, W. M., Kern, K. B., Pennock, G. D., Fenster, P. E., Huerta, B. J., Ohm, J., Dittrich, H. C., Kerridge, C., Keen, W., Swenson, M., Kopecky, S. L., Litin, S. C., Wiebers, D. O., Holland, A. E., Brown, R. D., Khandheria, B. K., Meissner, I., Tucker, K. R., Rothbart, R., Torelli, J., Schmidt, J., Murray, D., Ruzich, R. S., Loutfi, H., Appleton, C., Ingall, T., Carlson, L., Wilson, D., Dunn, M., Nolte, B., Edwards, C., Dick, A., Price, L. A., Janosik, D. L., Bjerregaard, P., Quattromani, A., Schiller, L., Labovitz, A., Burch, C., Parks, B. J., Thompson, D., Berarducci, L., Carey, S., Vigil, A., Falk, R., Battinelli, N., McNeil, M., Davidoff, R., Bernard, S., Bergethon, P., Fiori, L., Albers, G., Atwood, E., Clark, J., Tong, D., Yenari, M., Froelicker, V., Lutsep, H., Hock, N. H., Quaglietti, S., Kemp, S., Alpert, M. A., Rothrock, J. F., Hupp, C. H., Massey, C. V., Hamilton, W. J., Miller, V. T., Fox, J., Kronmal, R. A., McBride, R., Nasco, E., Pearce, L. A., Fletcher, K., Koehler, J., Hart, R. G., Sherman, D. G., Talbert, R. L., Heberling, P. A., Kajzer, C., Bovill, E., Geffken, D., Cornell, E., Nightingale, S., Blackshear, J. L., Halperin, J. L., Hart, R. G., Laupacis, A., McAnulty, J. H., McBride, R., Kelsy, S. P., Levy, D. E., Marsh, J. D., Welch, K. M. A., Marler, J. R. & Walker, M. D., Sep 7 1996, In : Lancet. 348, 9028, p. 633-638 6 p.

Research output: Contribution to journalArticle

Warfarin
Atrial Fibrillation
Aspirin
Randomized Controlled Trials
Stroke
26 Citations (Scopus)

E-Selectin expression on human brain microvascular endothelial cells

Hess, D. C., Thompson, Y., Sprinkle, A., Carroll, J. E. & Smith, J., Jul 26 1996, In : Neuroscience Letters. 213, 1, p. 37-40 4 p.

Research output: Contribution to journalArticle

E-Selectin
Endothelial Cells
Brain
Acetylcysteine
Dexamethasone