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Research Output 1991 2019

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Article
2019

Differential mechanisms of adenosine- and ATPγS-induced microvascular endothelial barrier strengthening

Bátori, R., Kumar, S., Bordán, Z., Cherian-Shaw, M., Kovács-Kása, A., MacDonald, J. A., Fulton, D. J., Erdődi, F. & Verin, A. D., May 1 2019, In : Journal of Cellular Physiology. 234, 5, p. 5863-5879 17 p.

Research output: Contribution to journalArticle

Endothelial cells
Adenosine
Endothelial Cells
Cyclic AMP-Dependent Protein Kinases
Cyclic AMP
2 Citations (Scopus)

Galectin-3 is expressed in vascular smooth muscle cells and promotes pulmonary hypertension through changes in proliferation, apoptosis, and fibrosis

Barman, S. A., Li, X., Haigh, S., Kondrikov, D., Mahboubi, K., Bordan, Z., Stepp, D. W., Zhou, J., Wang, Y., Weintraub, D. S., Traber, P., Snider, W., Jonigk, D., Sullivan, J., Ryan Crislip, G., Butcher, J. T., Thompson, J., Su, Y., Chen, F. & Fulton, D. J. R., May 2019, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 316, 5, p. L784-L797

Research output: Contribution to journalArticle

Galectin 3
Vascular Smooth Muscle
Pulmonary Hypertension
Smooth Muscle Myocytes
Fibrosis
Arginase
Vasodilation
Hyperglycemia
p38 Mitogen-Activated Protein Kinases
Phosphotransferases
1 Citation (Scopus)
Exosomes
Endothelial cells
MicroRNAs
Stem Cells
Myocardial Infarction

PFKFB3-mediated endothelial glycolysis promotes pulmonary hypertension

Cao, Y., Zhang, X., Wang, L., Yang, Q., Ma, Q., Xu, J., Wang, J., Kovacs, L., Ayon, R. J., Liu, Z., Zhang, M., Zhou, Y., Zeng, X., Xu, Y., Wang, Y., Fulton, D. J., Weintraub, N. L., Lucas, R., Dong, Z., Yuan, J. X. J. & 8 others, Sullivan, J. C., Meadows, L., Barman, S. A., Wu, C., Quan, J., Hong, M., Su, Y. & Huo, Y., Jan 1 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 27, p. 13394-13403 10 p.

Research output: Contribution to journalArticle

Open Access
Glycolysis
Pulmonary Hypertension
Lung
Endothelial Cells
Rodentia
1 Citation (Scopus)

Transcription factor TEAD1 is essential for vascular development by promoting vascular smooth muscle differentiation

Wen, T., Liu, J., He, X., Dong, K., Hu, G., Yu, L., Yin, Q., Osman, I., Peng, J., Zheng, Z., Xin, H., Fulton, D. J., Du, Q., Zhang, W. & Zhou, J., Dec 1 2019, In : Cell Death and Differentiation. 26, 12, p. 2790-2806 17 p.

Research output: Contribution to journalArticle

Vascular Smooth Muscle
Smooth Muscle Myocytes
Blood Vessels
Transcription Factors
Cardiac Myocytes
2018

Ablation of Myeloid ADK (Adenosine Kinase) Epigenetically Suppresses Atherosclerosis in ApoE-/- (Apolipoprotein E Deficient) Mice

Zhang, M., Zeng, X., Yang, Q., Xu, J., Liu, Z., Zhou, Y., Cao, Y., Zhang, X., An, X., Xu, Y., Huang, L., Han, Z., Wang, T., Wu, C., Fulton, D. J., Weintraub, N. L., Hong, M. & Huo, Y., Dec 1 2018, In : Arteriosclerosis, thrombosis, and vascular biology. 38, 12, p. 2780-2792 13 p.

Research output: Contribution to journalArticle

Adenosine Kinase
Apolipoproteins E
Atherosclerosis
Foam Cells
Myeloid Cells

Extracellular adenosine-induced Rac1 activation in pulmonary endothelium: Molecular mechanisms and barrier-protective role

Kovacs-Kasa, A., Kim, K. M., Cherian-Shaw, M., Black, S. M., Fulton, D. J. & Verin, A. D., Aug 2018, In : Journal of Cellular Physiology. 233, 8, p. 5736-5746 11 p.

Research output: Contribution to journalArticle

Acoustic impedance
Adenosine
Endothelium
Endothelial cells
Electric Impedance
7 Citations (Scopus)

Hsp70 suppresses mitochondrial reactive oxygen species and preserves pulmonary microvascular barrier integrity following exposure to bacterial toxins

Li, X., Yu, Y., Gorshkov, B., Haigh, S., Bordan, Z., Weintraub, D., Rudic, R. D., Chakraborty, T., Barman, S. A., Verin, A. D., Su, Y., Lucas, R., Stepp, D. W., Chen, F. & Fulton, D. J., Jun 12 2018, In : Frontiers in immunology. 9, JUN, 1309.

Research output: Contribution to journalArticle

Bacterial Toxins
geranylgeranylacetone
Reactive Oxygen Species
Lung
Pneumonia
4 Citations (Scopus)

Increased muscle mass protects against hypertension and renal injury in obesity

Butcher, J. T., Mintz, J. D., Larion, S., Qiu, S., Ruan, L., Fulton, D. J. & Stepp, D. W., Aug 1 2018, In : Journal of the American Heart Association. 7, 16, e009358.

Research output: Contribution to journalArticle

Myostatin
Renal Hypertension
Obesity
Muscles
Wounds and Injuries
3 Citations (Scopus)

Mechanisms of diabetes-induced endothelial cell senescence: Role of arginase 1

Shosha, E., Xu, Z., Priya Narayanan, S., Lemtalsi, T., Fouda, A. Y., Rojas, M., Xing, J., Fulton, D., William Caldwell, R. & Caldwell, R. B., Apr 17 2018, In : International journal of molecular sciences. 19, 4, 1215.

Research output: Contribution to journalArticle

Arginase
Cell Aging
Endothelial cells
Medical problems
Endothelial Cells
7 Citations (Scopus)
Cardiac Myocytes
Cullin Proteins
Heart Failure
Ubiquitins
cdc Genes

Neurofibromin deficiency induces endothelial cell proliferation and retinal neovascularization

Zhang, H., Hudson, F. Z., Xu, Z., Tritz, R., Rojas, M., Patel, C., Haigh, S. B., Bordán, Z., Ingram, D. A., Fulton, D. J., Weintraub, N. L., Caldwell, R. B. & Stansfield, B. K., May 2018, In : Investigative Ophthalmology and Visual Science. 59, 6, p. 2520-2528 9 p.

Research output: Contribution to journalArticle

Neurofibromin 1
Retinal Neovascularization
Retina
Neurofibromatosis 1
Endothelial Cells
5 Citations (Scopus)

PRKAA1/AMPKα1-driven glycolysis in endothelial cells exposed to disturbed flow protects against atherosclerosis

Yang, Q., Xu, J., Ma, Q., Liu, Z., Varadarajan, S., Cao, Y., Wang, L., Zeng, X., Zhou, Y., Zhang, M., Xu, Y., Wang, Y., Weintraub, N. L., Zhang, C., Fukai, T., Wu, C., Huang, L., Han, Z., Wang, T., Fulton, D. J. & 2 others, Hong, M. & Huo, Y., Dec 1 2018, In : Nature Communications. 9, 1, 4667.

Research output: Contribution to journalArticle

glycolysis
arteriosclerosis
Endothelial cells
Glycolysis
Atherosclerosis
6 Citations (Scopus)

Vasodilator dysfunction and oligodendrocyte dysmaturation in aging white matter

Bagi, Z., Brandner, D. D., Le, P., McNeal, D. W., Gong, X., Dou, H., Fulton, D. J., Beller, A., Ngyuen, T., Larson, E. B., Montine, T. J., Keene, C. D. & Back, S. A., Jan 1 2018, In : Annals of Neurology. 83, 1, p. 142-152 11 p.

Research output: Contribution to journalArticle

Oligodendroglia
Vasodilator Agents
Brain Injuries
Blood Vessels
Dementia
2017
5 Citations (Scopus)

A novel role for the Wnt inhibitor APCDD1 in adipocyte differentiation: Implications for diet-induced obesity

Yiew, N. K. H., Chatterjee, T. K., Tang, Y. L., Pellenberg, R., Stansfield, B. K., Bagi, Z., Fulton, D. J., Stepp, D. W., Chen, W., Patel, V., Kamath, V. M., Litwin, S. E., Hui, D. Y., Rudich, S. M., Kim, H. W. & Weintraub, N. L., Apr 14 2017, In : Journal of Biological Chemistry. 292, 15, p. 6312-6324 13 p.

Research output: Contribution to journalArticle

Adenomatous Polyposis Coli
Nutrition
Adipocytes
Obesity
Diet
6 Citations (Scopus)

Differential Regulation of BMAL1, CLOCK, and Endothelial Signaling in the Aortic Arch and Ligated Common Carotid Artery

Shang, X., Pati, P., Anea, C. B., Fulton, D. J. R. & Rudic, R. D., Jan 1 2017, In : Journal of Vascular Research. 53, 5-6, p. 269-278 10 p.

Research output: Contribution to journalArticle

Common Carotid Artery
Thoracic Aorta
Nitric Oxide Synthase Type III
Circadian Clocks
Acetylcholine
5 Citations (Scopus)

Effect of myostatin deletion on cardiac and microvascular function

Butcher, J. T., Ali, M. I., Ma, M. W., McCarthy, C. G., Islam, B. N., Fox, L. G., Mintz, J. D., Larion, S., Fulton, D. J. & Stepp, D. W., Dec 2017, In : Physiological reports. 5, 23, e13525.

Research output: Contribution to journalArticle

Myostatin
Muscles
Adrenergic Agents
Exercise
Blood Vessels
12 Citations (Scopus)

Endothelial adenosine A2a receptor-mediated glycolysis is essential for pathological retinal angiogenesis

Liu, Z., Yan, S., Wang, J., Xu, Y., Wang, Y., Zhang, S., Xu, X., Yang, Q., Zeng, X., Zhou, Y., Gu, X., Lu, S., Fu, Z., Fulton, D. J., Weintraub, N. L., Caldwell, R. B., Zhang, W., Wu, C., Liu, X. L., Chen, J. F. & 10 others, Ahmad, A., Kaddour-Djebbar, I., Al-Shabrawey, M., Li, Q., Jiang, X., Sun, Y., Sodhi, A., Smith, L., Hong, M. & Huo, Y., Dec 1 2017, In : Nature Communications. 8, 1, 584.

Research output: Contribution to journalArticle

glycolysis
Pathologic Neovascularization
angiogenesis
adenosines
Purinergic P1 Receptors
22 Citations (Scopus)

Epigenetic regulation of interleukin 6 by histone acetylation in macrophages and its role in paraquat-induced pulmonary fibrosis

Hu, L., Yu, Y., Huang, H., Fan, H., Hu, L., Yin, C., Li, K., Fulton, D. J. & Chen, F., Jan 30 2017, In : Frontiers in immunology. 7, JAN, 696.

Research output: Contribution to journalArticle

Paraquat
Pulmonary Fibrosis
Acetylation
Epigenomics
Histones
11 Citations (Scopus)

Epithelial sodium channel-α mediates the protective effect of the TNF-derived TIP peptide in pneumolysin-induced endothelial barrier dysfunction

Czikora, I., Alli, A. A., Sridhar, S., Matthay, M. A., Pillich, H., Hudel, M., Berisha, B., Gorshkov, B. A., Romero Lucas, M. J., Gonzales, J. N., Wu, G., Huo, Y., Su, Y., Verin, A. D., Fulton, D. J., Chakraborty, T., Eaton, D. C. & Lucas, R., Jul 21 2017, In : Frontiers in immunology. 8, JUL, 842.

Research output: Contribution to journalArticle

Epithelial Sodium Channels
Endothelial Cells
Acid Sensing Ion Channels
Lung
Peptides
11 Citations (Scopus)

Genetic deletion of NADPH oxidase 1 rescues microvascular function in mice with metabolic disease

Thompson, J. A., Larion, S., Mintz, J. D., Belin De Chantemèle, E. J., Fulton, D. J. & Stepp, D. W., Aug 1 2017, In : Circulation research. 121, 5, p. 502-511 10 p.

Research output: Contribution to journalArticle

Metabolic Diseases
Acetylcholine
Reactive Oxygen Species
Blood Vessels
Mesenteric Arteries
19 Citations (Scopus)

Intracellular adenosine regulates epigenetic programming in endothelial cells to promote angiogenesis

Xu, Y., Wang, Y., Yan, S., Zhou, Y., Yang, Q., Pan, Y., Zeng, X., An, X., Liu, Z., Wang, L., Xu, J., Cao, Y., Fulton, D. J., Weintraub, N. L., Bagi, Z., Hoda, MD. N., Wang, X., Li, Q., Hong, M., Jiang, X. & 4 others, Boison, D., Weber, C., Wu, C. & Huo, Y., Sep 2017, In : EMBO Molecular Medicine. 9, 9, p. 1263-1278 16 p.

Research output: Contribution to journalArticle

Adenosine Kinase
Epigenomics
Adenosine
Endothelial Cells
Methylation
11 Citations (Scopus)

Regulation of endothelial intracellular adenosine via adenosine kinase epigenetically modulates vascular inflammation

Xu, Y., Wang, Y., Yan, S., Yang, Q., Zhou, Y., Zeng, X., Liu, Z., An, X., Flores Toque, H. A., Dong, Z., Jiang, X., Fulton, D. J., Weintraub, N. L., Li, Q., Bagi, Z., Hong, M., Boison, D., Wu, C. & Huo, Y., Dec 1 2017, In : Nature Communications. 8, 1, 986.

Research output: Contribution to journalArticle

Adenosine Kinase
adenosines
Adenosine
Blood Vessels
Inflammation
4 Citations (Scopus)

RhoA S-nitrosylation as a regulatory mechanism influencing endothelial barrier function in response to G+-bacterial toxins

Chen, F., Wang, Y., Rafikov, R., Haigh, S., Kumar, S., Rafikova, O., Lucas, R., Verin, A. D., Black, S. M. & Fulton, D. J. R., Mar 1 2017, In : Biochemical Pharmacology. 127, p. 34-45 12 p.

Research output: Contribution to journalArticle

Bacterial Toxins
Nitric Oxide
glutathione-independent formaldehyde dehydrogenase
Lung
Calcium
7 Citations (Scopus)

Role of Adipose Tissue Endothelial ADAM17 in Age-Related Coronary Microvascular Dysfunction

Dou, H., Feher, A., Davila, A. C., Romero, M. J., Patel, V. S., Kamath, V. M., Gooz, M. B., Rudic, R. D., Lucas, R., Fulton, D. J., Weintraub, N. L. & Bagi, Z., Jun 1 2017, In : Arteriosclerosis, thrombosis, and vascular biology. 37, 6, p. 1180-1193 14 p.

Research output: Contribution to journalArticle

Adipose Tissue
Caveolin 1
Tumor Necrosis Factor-alpha
Obesity
Dilatation
6 Citations (Scopus)

Role of myeloperoxidase in abdominal aortic aneurysm formation: Mitigation by taurine

Kim, H. W., Blomkalns, A. L., Ogbi, M., Thomas, M., Gavrila, D., Neltner, B. S., Cassis, L. A., Thompson, R. W., Weiss, R. M., Lindower, P. D., Blanco, V. M., McCormick, M. L., Daugherty, A., Fu, X., Hazen, S. L., Stansfield, B. K., Huo, Y., Fulton, D. J., Chatterjee, T. K. & Weintraub, N. L., Dec 1 2017, In : American Journal of Physiology - Heart and Circulatory Physiology. 313, 6, p. H1168-H1179

Research output: Contribution to journalArticle

Taurine
Abdominal Aortic Aneurysm
Peroxidase
Gene Deletion
Neutrophils
2016
8 Citations (Scopus)

Cloning, characteristics, and functional analysis of rabbit NADPH oxidase 5

Chen, F., Yin, C., Dimitropoulou, C. & Fulton, D. J. R., Jul 19 2016, In : Frontiers in Physiology. 7, JUL, 284.

Research output: Contribution to journalArticle

NADPH Oxidase
Organism Cloning
Rabbits
MicroRNAs
Superoxides
11 Citations (Scopus)

Endotoxin disrupts circadian rhythms in macrophages via reactive oxygen species

Wang, Y., Pati, P., Xu, Y., Chen, F., Stepp, D. W., Huo, Y., Rudic, R. D. & Fulton, D. J. R., May 1 2016, In : PloS one. 11, 5, e0155075.

Research output: Contribution to journalArticle

Macrophages
endotoxins
Circadian Rhythm
Endotoxins
circadian rhythm
6 Citations (Scopus)

Hsp90 inhibition suppresses NF-ĸB transcriptional activation via Sirt-2 in human lung microvascular endothelial cells

Thangjam, G. S., Birmpas, C., Barabutis, N., Gregory, B. W., Clemens, M. A., Newton, J. R., Fulton, D. & Catravas, J. D., May 15 2016, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 310, 10, p. L964-L974

Research output: Contribution to journalArticle

HSP90 Heat-Shock Proteins
RNA Polymerase II
Histones
Transcriptional Activation
Sirtuin 2
33 Citations (Scopus)
Histone Deacetylases
NADPH Oxidase
Transcription
Pulmonary Hypertension
Reactive Oxygen Species
31 Citations (Scopus)

Low-dose IL-17 therapy prevents and reverses diabetic nephropathy, metabolic syndrome, and associated organ fibrosis

Mohamed, R., Jayakumar, C., Chen, F., Fulton, D., Stepp, D., Gansevoort, R. T. & Ramesh, G., Mar 2016, In : Journal of the American Society of Nephrology. 27, 3, p. 745-765 21 p.

Research output: Contribution to journalArticle

Interleukin-17
Diabetic Nephropathies
Fibrosis
Therapeutics
AMP-Activated Protein Kinases
11 Citations (Scopus)

Low-Salt Diet and Circadian Dysfunction Synergize to Induce Angiotensin II-Dependent Hypertension in Mice

Pati, P., Fulton, D. J. R., Bagi, Z., Chen, F., Wang, Y., Kitchens, J., Cassis, L. A., Stepp, D. W. & Rudic, R. D., Mar 1 2016, In : Hypertension. 67, 3, p. 661-668 8 p.

Research output: Contribution to journalArticle

Sodium-Restricted Diet
Angiotensin II
Blood Pressure
Hypertension
Knockout Mice
11 Citations (Scopus)

Neurofibromin is a novel regulator of Ras-induced reactive oxygen species production in mice and humans

Bessler, W. K., Hudson, F. Z., Zhang, H., Harris, V., Wang, Y., Mund, J. A., Downing, B., Ingram, D. A., Case, J., Fulton, D. J. & Stansfield, B. K., Aug 1 2016, In : Free Radical Biology and Medicine. 97, p. 212-222 11 p.

Research output: Contribution to journalArticle

Neurofibromin 1
Neurofibromatosis 1
Macrophages
Reactive Oxygen Species
Neointima
1 Citation (Scopus)

Pressor recovery after acute stress is impaired in high fructose-fed Lean Zucker rats

Thompson, J. A., D'Angelo, G., Mintz, J. D., Fulton, D. J. & Stepp, D. W., Jun 1 2016, In : Physiological reports. 4, 12, e12758.

Research output: Contribution to journalArticle

Zucker Rats
Fructose
Arterial Pressure
Isoproterenol
Blood Pressure
6 Citations (Scopus)
Growth Hormone-Releasing Hormone
Dyslipidemias
Glucagon-Like Peptide 1
Type 1 Diabetes Mellitus
Lipoproteins
3 Citations (Scopus)

The protective role of MLCP-mediated ERM dephosphorylation in endotoxin-induced lung injury in vitro and in vivo

Kovacs-Kasa, A., Gorshkov, B. A., Kim, K. M., Kumar, S., Black, S. M., Fulton, D. J., Dimitropoulou, C., Catravas, J. D. & Verin, A. D., Dec 15 2016, In : Scientific Reports. 6, 39018.

Research output: Contribution to journalArticle

Lung Injury
Phosphoric Monoester Hydrolases
Endotoxins
Acute Lung Injury
Permeability
6 Citations (Scopus)

TNFα reduces eNOS activity in endothelial cells through serine 116 phosphorylation and Pin1 binding: Confirmation of a direct, inhibitory interaction of Pin1 with eNOS

Kennard, S., Ruan, L., Buffett, R. J., Fulton, D. & Venema, R. C., Jun 1 2016, In : Vascular Pharmacology. 81, p. 61-68 8 p.

Research output: Contribution to journalArticle

Nitric Oxide Synthase Type III
Serine
Endothelial Cells
Phosphorylation
Proline
2015
9 Citations (Scopus)
Caveolin 1
Constriction
Angiotensin II
Arteries
Obesity
7 Citations (Scopus)
Apoptosis Inducing Factor
hyperoxia
Hyperoxia
HSP70 Heat-Shock Proteins
caspases
17 Citations (Scopus)

Nox5 stability and superoxide production is regulated by C-terminal binding of Hsp90 and CO-chaperones

Chen, F., Haigh, S., Yu, Y., Benson, T., Wang, Y., Li, X., Dou, H., Bagi, Z., Verin, A. D., Stepp, D. W., Csanyi, G., Chadli, A., Weintraub, N. L., Smith, S. M. E. & Fulton, D. J., Dec 1 2015, In : Free Radical Biology and Medicine. 89, p. 793-805 13 p.

Research output: Contribution to journalArticle

HSP90 Heat-Shock Proteins
Carbon Monoxide
Superoxides
Enzyme activity
Protein Binding
7 Citations (Scopus)

Obesity Alters the Peripheral Circadian Clock in the Aorta and Microcirculation

Nernpermpisooth, N., Qiu, S., Mintz, J. D., Suvitayavat, W., Thirawarapan, S., Rudic, R. D., Fulton, D. J. & Stepp, D. W., Jan 1 2015, In : Microcirculation. 22, 4, p. 257-266 10 p.

Research output: Contribution to journalArticle

Circadian Clocks
Microcirculation
Aorta
Obesity
Obese Mice
22 Citations (Scopus)

Red blood cell dysfunction induced by high-fat diet: Potential implications for obesity-related atherosclerosis

Unruh, D., Srinivasan, R., Benson, T., Haigh, S., Coyle, D., Batra, N., Keil, R., Sturm, R., Blanco, V., Palascak, M., Franco, R. S., Tong, W., Chatterjee, T., Hui, D. Y., Davidson, W. S., Aronow, B. J., Kalfa, T., Manka, D., Peairs, A., Blomkalns, A. & 4 others, Fulton, D. J., Brittain, J. E., Weintraub, N. L. & Bogdanov, V. Y., Nov 17 2015, In : Circulation. 132, 20, p. 1898-1908 11 p.

Research output: Contribution to journalArticle

High Fat Diet
Atherosclerosis
Obesity
Erythrocytes
Macrophages
2014
39 Citations (Scopus)

Caveolin-1 is a negative regulator of NADPH oxidase-derived reactive oxygen species

Chen, F., Barman, S. A., Yu, Y., Haigh, S., Wang, Y., Dou, H., Bagi, Z., Han, W., Su, Y. & Fulton, D. J., Jan 1 2014, In : Free Radical Biology and Medicine. 73, p. 201-213 13 p.

Research output: Contribution to journalArticle

Caveolin 1
NADPH Oxidase
Reactive Oxygen Species
Pulmonary Artery
Pulmonary Hypertension
82 Citations (Scopus)

Endothelial PFKFB3 plays a critical role in angiogenesis

Xu, Y., An, X., Guo, X., Habtetsion, T. G., Wang, Y., Xu, X., Kandala, S., Li, Q., Li, H., Zhang, C., Caldwell, R. B., Fulton, D. J., Su, Y., Hoda, MD. N., Zhou, G., Wu, C. & Huo, Y., Jun 2014, In : Arteriosclerosis, thrombosis, and vascular biology. 34, 6, p. 1231-1239 9 p.

Research output: Contribution to journalArticle

Phosphofructokinase-2
Protein Isoforms
Glycolysis
Endothelial Cells
Lactic Acid
34 Citations (Scopus)

Heat shock protein 90 inhibitors prevent lps-induced endothelial barrier dysfunction by disrupting Rhoa signaling

Joshi, A. D., Dimitropoulou, C., Thangjam, G., Snead, C., Feldman, S., Barabutis, N., Fulton, D., Hou, Y., Kumar, S., Patel, V., Gorshkov, B., Verin, A. D., Black, S. M. & Catravas, J. D., Jan 1 2014, In : American journal of respiratory cell and molecular biology. 50, 1, p. 170-179 10 p.

Research output: Contribution to journalArticle

HSP90 Heat-Shock Proteins
tanespimycin
Endothelial cells
Myosin Light Chains
Phosphorylation
16 Citations (Scopus)

Impact of Nox5 polymorphisms on basal and stimulus-dependent ROS generation

Wang, Y., Chen, F., Le, B., Stepp, D. W. & Fulton, D. J. R., Jul 3 2014, In : PloS one. 9, 7, e100102.

Research output: Contribution to journalArticle

Polymorphism
reactive oxygen species
Reactive Oxygen Species
Enzyme activity
genetic polymorphism
16 Citations (Scopus)

Increasing muscle mass improves vascular function in obese (DB/DB) Mice

Qiu, S., Mintz, J. D., Salet, C. D., Han, W., Giannis, A., Chen, F., Yu, Y., Su, Y., Fulton, D. J. & Stepp, D. W., Jan 1 2014, In : Journal of the American Heart Association. 3, 3, 000854.

Research output: Contribution to journalArticle

Myostatin
Obese Mice
Blood Vessels
Vasodilation
Muscles
29 Citations (Scopus)

Lipopolysaccharide-induced lung injury involves the nitration-mediated activation of RhoA

Rafikov, R., Dimitropoulou, C., Aggarwal, S., Kangath, A., Gross, C., Pardo, D., Sharma, S., Jezierska-Drutel, A., Patel, V., Snead, C., Lucas, R., Verin, A., Fulton, D., Catravas, J. D. & Black, S. M., Feb 21 2014, In : Journal of Biological Chemistry. 289, 8, p. 4710-4722 13 p.

Research output: Contribution to journalArticle

Nitration
Acute Lung Injury
Lung Injury
Lipopolysaccharides
Chemical activation
65 Citations (Scopus)

NADPH oxidase 4 is expressed in pulmonary artery adventitia and contributes to hypertensive vascular remodeling

Barman, S. A., Chen, F., Su, Y., Dimitropoulou, C., Wang, Y., Catravas, J. D., Han, W., Orfi, L., Szantai-Kis, C., Keri, G., Szabadkai, I., Barabutis, N., Rafikova, O., Rafikov, R., Black, S. M., Jonigk, D., Giannis, A., Asmis, R., Stepp, D. W., Ramesh, G. & 1 others, Fulton, D. J., Aug 2014, In : Arteriosclerosis, thrombosis, and vascular biology. 34, 8, p. 1704-1715 12 p.

Research output: Contribution to journalArticle

Adventitia
NADPH Oxidase
Pulmonary Artery
Pulmonary Hypertension
Fibroblasts