• 480 Citations
  • 10 h-Index
19952019
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Research Output 1995 2019

  • 480 Citations
  • 10 h-Index
  • 35 Article
2019
1 Citation (Scopus)

Monosodium urate contributes to retinal inflammation and progression of diabetic retinopathy

Thounaojam, M., Montemari, A., Powell, F. L., Malla, P., Gutsaeva, D. R., Bachettoni, A., Ripandelli, G., Repossi, A., Tawfik, A. M., Martin, P. M., Facchiano, F. & Bartoli, M., Jan 1 2019, In : Diabetes. 68, 5, p. 1014-1025 12 p.

Research output: Contribution to journalArticle

Open Access
Diabetic Retinopathy
Uric Acid
Inflammation
Streptozocin
Hyperglycemia
2017
11 Citations (Scopus)
Growth Hormone-Releasing Hormone
Diabetic Retinopathy
Retina
Streptozocin
Hormone Antagonists
5 Citations (Scopus)

STAT3-mediated activation of miR-21 is involved in downregulation of TIMP3 and neovascularization in the ischemic retina

Gutsaeva, D. R., Thounaojam, M., Rajpurohit, S., Powell, F. L., Martin, P. M., Goei, S., Duncan, M. & Bartoli, M., Jan 1 2017, In : Oncotarget. 8, 61, p. 103568-103580 13 p.

Research output: Contribution to journalArticle

Tissue Inhibitor of Metalloproteinase-3
STAT3 Transcription Factor
Matrix Metalloproteinase 3
Retinal Neovascularization
MicroRNAs
2016
4 Citations (Scopus)

Oral Monomethyl Fumarate Therapy Ameliorates Retinopathy in a Humanized Mouse Model of Sickle Cell Disease

Promsote, W., Powell, F. L., Veean, S., Thounaojam, M., Markand, S., Saul, A., Gutsaeva, D., Bartoli, M., Smith, S. B., Ganapathy, V. & Martin, P. M., Dec 10 2016, In : Antioxidants and Redox Signaling. 25, 17, p. 921-935 15 p.

Research output: Contribution to journalArticle

Fumarates
Sickle Cell Anemia
Oxidative stress
Pathology
Oxidative Stress
2014
17 Citations (Scopus)

Molecular mechanisms underlying synergistic adhesion of sickle red blood cells by hypoxia and low nitric oxide bioavailability

Gutsaeva, D. R., Montero-Huerta, P., Parkerson, J. B., Yerigenahally, S. D., Ikuta, T. & Head, C. A., Mar 20 2014, In : Blood. 123, 12, p. 1917-1926 10 p.

Research output: Contribution to journalArticle

Cell Hypoxia
Cell adhesion
Biological Availability
Cell Adhesion
Nitric Oxide
2011
70 Citations (Scopus)

Inhibition of cell adhesion by anti-P-selectin aptamer: A new potential therapeutic agent for sickle cell disease

Gutsaeva, D. R., Parkerson, J. B., Yerigenahally, S. D., Kurz, J. C., Schaub, R. G., Ikuta, T. & Head, C. A., Jan 13 2011, In : Blood. 117, 2, p. 727-735 9 p.

Research output: Contribution to journalArticle

P-Selectin
Cell adhesion
Sickle Cell Anemia
Cell Adhesion
Endothelial cells
8 Citations (Scopus)

The proinflammatory cytokine GM-CSF downregulates fetal hemoglobin expression by attenuating the cAMP-dependent pathway in sickle cell disease

Ikuta, T., Adekile, A. D., Gutsaeva, D. R., Parkerson, J. B., Yerigenahally, S. D., Clair, B., Kutlar, A., Odo, N. & Head, C. A., Dec 15 2011, In : Blood Cells, Molecules, and Diseases. 47, 4, p. 235-242 8 p.

Research output: Contribution to journalArticle

Fetal Hemoglobin
Sickle Cell Anemia
Granulocyte-Macrophage Colony-Stimulating Factor
Down-Regulation
Cytokines
2010
10 Citations (Scopus)

Involvement of extracellular superoxide dismutase in regulating brain blood flow

Demchenko, I. T., Gutsaeva, D. R., Moskvin, A. N. & Zhilyaev, S. Y., Jan 1 2010, In : Neuroscience and Behavioral Physiology. 40, 2, p. 173-178 6 p.

Research output: Contribution to journalArticle

Superoxide Dismutase
Nitric Oxide
Brain
Superoxides
Blood Vessels
2009

Hypoxia preadaptation to nitrogen anesthesia and heat shock proteins in neurons of the cerebral cortex

Alekseeva, O. S., Korzhevskii, D. E., Otellin, V. A., Vetosh, A. N., Kostkin, V. B. & Gutsaeva, D. R., Apr 1 2009, In : Doklady Biological Sciences. 425, 1, p. 104-106 3 p.

Research output: Contribution to journalArticle

cerebral cortex
Heat-Shock Proteins
heat shock proteins
Cerebral Cortex
hypoxia
2008
26 Citations (Scopus)

Contributions of nitric oxide synthase isoforms to pulmonary oxygen toxicity, local vs. mediated effects

Demchenko, I. T., Atochin, D. N., Gutsaeva, D. R., Godfrey, R. R., Huang, P. L., Piantadosi, C. A. & Allen, B. W., May 1 2008, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 294, 5, p. L984-L990

Research output: Contribution to journalArticle

Lung Injury
Hyperoxia
Nitric Oxide Synthase
Protein Isoforms
Oxygen

Involvement of extracellular superoxide dismutase in cerebral blood flow regulation

Demchenko, I. T., Gutsaeva, D. R., Moskvin, A. N. & Zhiliaev, S. I., Dec 1 2008, In : Rossiǐskii fiziologicheskiǐ zhurnal imeni I.M. Sechenova / Rossiǐskaia akademiia nauk. 94, 12, p. 1365-1373 9 p.

Research output: Contribution to journalArticle

Cerebrovascular Circulation
Superoxide Dismutase
Nitric Oxide
Nitric Oxide Donors
Microdialysis
137 Citations (Scopus)

Transient hypoxia stimulates mitochondrial biogenesis in brain subcortex by a neuronal nitric oxide synthase-dependent mechanism

Gutsaeva, D. R., Carraway, M. S., Suliman, H. B., Demchenko, I. T., Shitara, H., Yonekawa, H. & Piantadosi, C. A., Feb 27 2008, In : Journal of Neuroscience. 28, 9, p. 2015-2024 10 p.

Research output: Contribution to journalArticle

Nitric Oxide Synthase Type I
Organelle Biogenesis
Brain
Response Elements
Mitochondrial DNA
2006
2 Citations (Scopus)

Effect of indomethacin on cerebral blood flow and development of oxygen convulsions

Moskvin, A. N., Alekseeva, O. S., Gutsaeva, D. R., Khmel'nitskii, A. V. & Sharapov, O. I., Jul 1 2006, In : Bulletin of Experimental Biology and Medicine. 142, 1, p. 26-28 3 p.

Research output: Contribution to journalArticle

Cerebrovascular Circulation
Oxygenation
Indomethacin
Hyperbaric Oxygenation
Seizures
42 Citations (Scopus)

Oxygen-induced mitochondrial biogenesis in the rat hippocampus

Gutsaeva, D. R., Suliman, H. B., Carraway, M. S., Demchenko, I. T. & Piantadosi, C. A., Jan 9 2006, In : Neuroscience. 137, 2, p. 493-504 12 p.

Research output: Contribution to journalArticle

Organelle Biogenesis
Mitochondrial DNA
Hippocampus
Oxygen
GA-Binding Protein Transcription Factor
2005
44 Citations (Scopus)

Cerebral blood flow and brain oxygenation in rats breathing oxygen under pressure

Demchenko, I. T., Luchakov, Y. I., Moskvin, A. N., Gutsaeva, D. R., Allen, B. W., Thalmann, E. D. & Piantadosi, C. A., Oct 1 2005, In : Journal of Cerebral Blood Flow and Metabolism. 25, 10, p. 1288-1300 13 p.

Research output: Contribution to journalArticle

Cerebrovascular Circulation
Regional Blood Flow
Respiration
Oxygen
Pressure
3 Citations (Scopus)

The roles of nitric oxide and carbon dioxide gas in the neurotoxic actions of oxygen under pressure

Gutsaeva, D. R., Moskvin, A. N., Zhilyaev, S. Y., Kostkin, V. B. & Demchenko, I. T., Sep 1 2005, In : Neuroscience and Behavioral Physiology. 35, 7, p. 751-756 6 p.

Research output: Contribution to journalArticle

Carbon Dioxide
Nitric Oxide
Gases
Acetazolamide
Oxygen
2004
7 Citations (Scopus)

Rol' oksida azota i uglekislogo gaza v neirotoksicheskom deistvii kisloroda pod davleniem.

Translated title of the contribution: Nitric oxide and carbon dioxide in neurotoxicity induced by oxygen under pressureGutsaeva, D. R., Moskvin, A. N., Zhiliaev, S. I., Kostkin, V. B. & Demchenko, I. T., Apr 1 2004, In : Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova / Rossiiskaia akademiia nauk. 90, 4, p. 428-436 9 p.

Research output: Contribution to journalArticle

Cerebrovascular Circulation
Acetazolamide
Carbon Dioxide
Nitric Oxide
Oxygen
2003
16 Citations (Scopus)

Brain Blood Flow Modulates the Neurotoxic Action of Hyperbaric Oxygen via Neuronal and Endothelial Nitric Oxide

Moskvin, A. N., Zhilyaev, S. Y., Sharapov, O. I., Platonova, T. F., Gutsaeva, D. R., Kostkin, V. B. & Demchenko, I. T., Nov 1 2003, In : Neuroscience and Behavioral Physiology. 33, 9, p. 883-888 6 p.

Research output: Contribution to journalArticle

Electroencephalography
Nitric Oxide
Nitric Oxide Synthase
Hyperbaric Oxygenation
Oxygen

Cell and tissue reaction of animal embryonic brain on hypoxia

Otellin, V. A., Khozhaj, L. I., Gilerovich, E. G., Korzhevskij, D. E., Gutsaeva, D. R., Demchenko, I. T., Kostkin, V. B. & Grigor'ev, I. P., Dec 1 2003, In : Doklady Akademii Nauk. 393, 5, p. 703-705 3 p.

Research output: Contribution to journalArticle

Brain Hypoxia
Brain
Embryonic Structures
Cell Hypoxia
Embryonic Development

Cell and tissue responses of embryonic animal brain to hypoxia.

Otellin, V. A., Khozhai, L. I., Gilerovich, E. G., Korzhevskii, D. E., Gutsaeva, D. R., Demchenko, I. T., Kostkin, V. B. & Grigor'ev, I. P., Jan 1 2003, In : Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections / translated from Russian. 393, p. 520-522 3 p.

Research output: Contribution to journalArticle

Rats
Brain
Nitric Oxide
Animals
Tissue
49 Citations (Scopus)

Hyperoxic Vasoconstriction in the Brain Is Mediated by Inactivation of Nitric Oxide by Superoxide Anions

Zhilyaev, S. Y., Moskvin, A. N., Platonova, T. F., Gutsaeva, D. R., Churilina, I. V. & Demchenko, I. T., Oct 1 2003, In : Neuroscience and Behavioral Physiology. 33, 8, p. 783-787 5 p.

Research output: Contribution to journalArticle

Vasoconstriction
Superoxides
Nitric Oxide
Superoxide Dismutase
Brain
2002
5 Citations (Scopus)

Giperoksicheskaia vazokonstriktsiia v golovnom mozgu realizuetsia putem inaktivatsii oksida azota superoksidnymi anionami.

Translated title of the contribution: Hyperoxic vasoconstriction in the brain is realized by inactivation of nitric oxide by superoxide anionsZhiliaev, S. I., Moskvin, A. N., Platonova, T. F., Gutsaeva, D. R., Churilina, I. V. & Demchenko, I. T., Jan 1 2002, In : Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova / Rossiiskaia akademiia nauk. 88, 5, p. 553-559 7 p.

Research output: Contribution to journalArticle

Cerebrovascular Circulation
Hyperbaric Oxygenation
Vasoconstriction
Superoxides
Nitric Oxide
2 Citations (Scopus)

Mozgovoi krovotok moduliruet neirotoksicheskoe deistvie giperbaricheskogo kisloroda s pomoshch'iu neironal'nogo i endotelial'nogo oksida azota.

Translated title of the contribution: Cerebral blood flow modulates hyperbaric oxygen induced neurotoxicity by neuronal and endothelial nitric oxideMoskvin, A. N., Zhiliaev, S. I., Sharapov, O. I., Platonova, T. F., Gutsaeva, D. R., Kostkin, V. B. & Demchenko, I. T., Jul 2002, In : Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova / Rossiiskaia akademiia nauk. 88, 7, p. 873-880 8 p.

Research output: Contribution to journalArticle

Cerebrovascular Circulation
Nitric Oxide
Seizures
Oxygen
NG-Nitroarginine Methyl Ester

Role of nitric oxide in postnatal resistance of rats to neurotoxic action of hyperbaric oxygen

Gutsaeva, D. R., Moskvin, A. N., Kostkin, V. B. & Demchenko, I. T., Mar 1 2002, In : Journal of Evolutionary Biochemistry and Physiology. 38, 2, p. 245-247 3 p.

Research output: Contribution to journalArticle

nitric oxide
oxygen
rats
1 Citation (Scopus)

Rol' okisi azota v postnatal'noi ustoichivosti krys k neirotoksicheskomy deistviiu giperbaricheskogo kisloroda.

Translated title of the contribution: The role of nitric oxide in rat postnatal resistance to neurotoxic action of hyperbaric oxygenGutsaeva, D. R., Moskvin, A. N., Kostkin, V. B. & Demchenko, I. T., Mar 1 2002, In : Zhurnal Evolyutsionnoi Biokhimii i Fiziologii. 38, 2, p. 189-190 2 p.

Research output: Contribution to journalArticle

Nitric Oxide Donors
Nitroglycerin
Arginine
Rats
Brain
2000
1 Citation (Scopus)

Age and sex peculiarities of distribution of blood erythrocytes according to their electrophoretic mobility

Matyushichev, V. B., Sharmatova, V. G., Akhunova, A. R. & Gutsaeva, D. R., Jan 1 2000, In : Journal of Evolutionary Biochemistry and Physiology. 36, 3, p. 359-361 3 p.

Research output: Contribution to journalArticle

Electrophoretic mobility
Blood
1 Citation (Scopus)

Polovye i vozrastnye osobennosti raspredeleniia éritrotsitov krovi po ikh élektroforeticheskoi podvizhnosti.

Translated title of the contribution: Sex and age characteristics of the erythrocyte electrophoretic mobility distributionMatiushichev, V. B., Shamratova, V. G., Akhunova, A. P. & Gutsaeva, D. R., May 1 2000, In : Zhurnal Evolyutsionnoi Biokhimii i Fiziologii. 36, 3, p. 273-275 3 p.

Research output: Contribution to journalArticle

Electrophoretic mobility
Electrophoresis
9 Citations (Scopus)

Rol' oksida azota v tserebral'noi vazokonstriktsii u krys pri dykhanii kislorodom pod davleniiem.

Translated title of the contribution: Involvement of nitrogen oxide in the cerebral vasoconstriction during respiration with high pressure oxygenDemchenko, I. T., Bosso, A. E., Zhiliaev, S. I., Moskvin, A. N., Gutsaeva, D. R., Atochin, D. N., Bennett, P. B. & Piantadossi, K. A., Jan 1 2000, In : Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova / Rossiiskaia akademiia nauk. 86, 12, p. 1594-1603 10 p.

Research output: Contribution to journalArticle

Vasoconstriction
Cerebrovascular Circulation
Nitric Oxide
Respiration
Oxygen

Sushchestvuet li dykhatel'naia funktsiia trombotsitov krovi cheloveka?

Translated title of the contribution: Does a respiratory function exist for human blood thrombocytes?Matiushichev, V. B., Shamratova, V. G. & Gutsaeva, D. R., Jan 1 2000, In : Fiziologiia cheloveka. 26, 1, p. 65-69 5 p.

Research output: Contribution to journalArticle

Hypochromic Anemia
Erythrocyte Count
Platelet Count
Hematocrit
Statistical Factor Analysis
1999
5 Citations (Scopus)

Dinamika vzaimosviazi élektroforeticheskoi podvizhnosti i ob''ema éritrotsitov krovi krys pri stresse.

Translated title of the contribution: Dynamics of relationship of electrophoretic motility and erythrocyte volume in rats during stressMatiushichev, V. B., Shamratova, V. G. & Gutsaeva, D. R., Nov 1 1999, In : Byulleten Eksperimentalnoi Biologii i Meditsiny. 128, 11, p. 504-506 3 p.

Research output: Contribution to journalArticle

Blood Protein Electrophoresis
Erythrocyte Volume
Rats
Animals

Dynamics of correlation between erythrocyte electrophoretic mobility and volume in stress

Matyushichev, V. B., Shamratova, V. G. & Gutsaeva, D. R., Dec 1 1999, In : Bulletin of Experimental Biology and Medicine. 128, 11, p. 1094-1096 3 p.

Research output: Contribution to journalArticle

Erythrocyte Volume
Electrophoretic mobility
Cell Size
Psychological Stress
Erythrocytes
1 Citation (Scopus)

Kachestvennoe razlichie éritrotsitov krovi muzhchin i zhenshchin.

Translated title of the contribution: Qualitative difference in blood erythrocytes of men and womenMatiushichev, V. B., Shamratova, V. G., Muzapharova, D. A. & Gutsaeva, D. R., Oct 1 1999, In : Byulleten Eksperimentalnoi Biologii i Meditsiny. 128, 10, p. 372-374 3 p.

Research output: Contribution to journalArticle

Sex Characteristics
Animals
Blood
Erythrocytes
1 Citation (Scopus)

Qualitative difference between male and female erythrocytes

Matyushichev, V. B., Shamratova, V. G., Muzafarova, D. A. & Gutsaeva, D. R., Dec 1 1999, In : Bulletin of Experimental Biology and Medicine. 128, 10, p. 978-980 3 p.

Research output: Contribution to journalArticle

Hemoglobins
Erythrocytes
Erythrocyte Indices
Hematocrit
Cell Count
1995

Mekhanizmy kontrolia élektrokineticheskikh svoistv éritrotsitov krovi cheloveka pri émotsional'nom stresse.

Translated title of the contribution: The control mechanisms of the electrokinetic properties of human erythrocytes in emotional stressMatiushichev, V. B., Shamratova, V. G. & Gutsaeva, D. R., Dec 1 1995, In : Tsitologiia. 37, 8, p. 824-828 5 p.

Research output: Contribution to journalArticle

Psychological Stress
Erythrocytes
Students
Epinephrine
2 Citations (Scopus)

Sviaz' kislotno-shchelochnogo sostoianiia krovi s élektroforeticheskoi podvizhnost'iu éritrotsitov pri patologii pecheni.

Translated title of the contribution: The relationship of the acid-base status of the blood to the electrophoretic mobility of the erythrocytes in liver pathologyMatiushichev, V. B., Shamratova, C. G. & Gutsaeva, D. R., Dec 1 1995, In : Tsitologiia. 37, 5-6, p. 444-448 5 p.

Research output: Contribution to journalArticle

Erythrocytes
Pathology
Acids
Partial Pressure
Liver