• 5224 Citations
  • 38 h-Index
1983 …2020

Research output per year

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Research Output

  • 5224 Citations
  • 38 h-Index
  • 62 Article
  • 2 Chapter
  • 2 Comment/debate
  • 1 Review article
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Article
2020
2019
1 Scopus citations
2018
2 Scopus citations
2017

The transcriptional regulator of the chaperone response HSF1 controls hepatic bioenergetics and protein homeostasis

Qiao, A., Jin, X., Pang, J., Moskofidis, D. & Mivechi, N. F., Mar 6 2017, In : The Journal of cell biology. 216, 3, p. 723-741 19 p.

Research output: Contribution to journalArticle

15 Scopus citations
2014

An essential role for heat shock transcription factor binding protein 1 (HSBP1) during early embryonic development

Eroglu, B., Min, J. N., Zhang, Y., Szurek, E., Moskofidis, D., Eroglu, A. & Mivechi, N. F., Feb 15 2014, In : Developmental Biology. 386, 2, p. 448-460 13 p.

Research output: Contribution to journalArticle

12 Scopus citations

Therapeutic inducers of the HSP70/HSP110 protect mice against traumatic brain injury

Eroglu, B., Kimbler, D. E., Pang, J., Choi, J., Moskophidis, D., Yanasak, N., Dhandapani, K. M. & Mivechi, N. F., Sep 2014, In : Journal of Neurochemistry. 130, 5, p. 626-641 16 p.

Research output: Contribution to journalArticle

26 Scopus citations
2012

Heat shock factor Hsf1 cooperates with ErbB2 (Her2/Neu) protein to promote mammary tumorigenesis and metastasis

Xi, C., Hu, Y., Buckhaults, P., Moskophidis, D. & Mivechi, N. F., Oct 12 2012, In : Journal of Biological Chemistry. 287, 42, p. 35646-35657 12 p.

Research output: Contribution to journalArticle

50 Scopus citations

Inactivation of heat shock factor Hsf4 induces cellular senescence and suppresses tumorigenesis In Vivo

Jin, X., Eroglu, B., Cho, W., Yamaguchi, Y., Moskofidis, D. & Mivechi, N. F., Apr 1 2012, In : Molecular Cancer Research. 10, 4, p. 523-534 12 p.

Research output: Contribution to journalArticle

10 Scopus citations
2011
75 Scopus citations
2010
41 Scopus citations
2009

Heat shock factor 1 deficiency via its downstream target gene αB-crystallin (Hspb5) impairs p53 degradation

Jin, X., Moskophidis, D., Hu, Y., Phillips, A. & Mivechi, N. F., Jun 1 2009, In : Journal of cellular biochemistry. 107, 3, p. 504-515 12 p.

Research output: Contribution to journalArticle

22 Scopus citations
2008

Control of virus-specific CD8+ T-cell exhaustion and immune-mediated pathology by E3 ubiquitin ligase Cbl-b during chronic viral infection

Ou, R., Zhang, M., Huang, L. & Moskophidis, D., Apr 1 2008, In : Journal of Virology. 82, 7, p. 3353-3368 16 p.

Research output: Contribution to journalArticle

22 Scopus citations

Genomic and biological characterization of aggressive and docile strains of lymphocytic choriomeningitis virus rescued from a plasmid-based reverse-genetics system

Chen, M., Lan, S., Ou, R., Price, G. E., Jiang, H., de la Torre, J. C. & Moskophidis, D., Jun 1 2008, In : Journal of General Virology. 89, 6, p. 1421-1433 13 p.

Research output: Contribution to journalArticle

8 Scopus citations

Regulation of immune response and inflammatory reactions against viral infection by VCAM-1

Ou, R., Zhang, M., Huang, L., Flavell, R. A., Koni, P. A. & Moskophidis, D., Mar 1 2008, In : Journal of Virology. 82, 6, p. 2952-2965 14 p.

Research output: Contribution to journalArticle

19 Scopus citations
2007

Insights into function and regulation of small heat shock protein 25 (HSPB1) in a mouse model with targeted gene disruption

Huang, L., Min, J. N., Masters, S., Mivechi, N. F. & Moskofidis, D., Aug 1 2007, In : Genesis. 45, 8, p. 487-501 15 p.

Research output: Contribution to journalArticle

69 Scopus citations

Selective suppression of lymphomas by functional loss of Hsf1 in a p53-deficient mouse model for spontaneous tumors

Min, J. N., Huang, L., Zimonjic, D. B., Moskophidis, D. & Mivechi, N. F., Aug 2 2007, In : Oncogene. 26, 35, p. 5086-5097 12 p.

Research output: Contribution to journalArticle

113 Scopus citations
2005

Perforin and Fas cytolytic pathways coordinately shape the selection and diversity of CD8+-T-cell escape variants of influenza virus

Price, G. E., Huang, L., Ou, R., Zhang, M. & Moskophidis, D., Jul 1 2005, In : Journal of Virology. 79, 13, p. 8545-8559 15 p.

Research output: Contribution to journalArticle

18 Scopus citations
2004

Differential Tissue-Specific Regulation of Antiviral CD8+ T-Cell Immune Responses during Chronic Viral Infection

Zhou, S., Ou, R., Huang, L., Price, G. E. & Moskophidis, D., Apr 1 2004, In : Journal of Virology. 78, 7, p. 3578-3600 23 p.

Research output: Contribution to journalArticle

72 Scopus citations

Essential Requirement for Both hsf1 and hsf2 Transcriptional Activity in Spermatogenesis and Male Fertility

Wang, G., Ying, Z., Jin, X., Tu, N., Zhang, Y., Phillips, M., Moskophidis, D. & Mivechi, N. F., Feb 1 2004, In : Genesis. 38, 2, p. 66-80 15 p.

Research output: Contribution to journalArticle

79 Scopus citations

TCR affinity and negative regulation limit autoimmunity

Gronski, M. A., Boulter, J. M., Moskophidis, D., Nguyen, L. T., Holmberg, K., Elford, A. R., Deenick, E. K., Kim, H. O., Penninger, J. M., Odermatt, B., Gallimore, A., Gascoigne, N. R. J. & Ohashi, P. S., Nov 1 2004, In : Nature Medicine. 10, 11, p. 1234-1239 6 p.

Research output: Contribution to journalArticle

123 Scopus citations

Unique contribution of heat shock transcription factor 4 in ocular lens development and fiber cell differentiation

Min, J. N., Zhang, Y., Moskophidis, D. & Mivechi, N. F., Dec 1 2004, In : Genesis. 40, 4, p. 205-217 13 p.

Research output: Contribution to journalArticle

91 Scopus citations
2003
102 Scopus citations
2002
81 Scopus citations
112 Scopus citations
2001
114 Scopus citations
197 Scopus citations
2000

The role of alpha/beta and gamma interferons in development of immunity to influenza A virus in mice

Price, G. E., Gaszewska-Mastarlarz, A. & Moskophidis, D., May 2 2000, In : Journal of Virology. 74, 9, p. 3996-4003 8 p.

Research output: Contribution to journalArticle

145 Scopus citations

Viral escape by selection of cytotoxic T cell-resistant variants in influenza a virus pneumonia

Price, G. E., Ou, R., Jiang, H., Huang, L. & Moskophidis, D., Jun 5 2000, In : Journal of Experimental Medicine. 191, 11, p. 1853-1867 15 p.

Research output: Contribution to journalArticle

74 Scopus citations
1998
147 Scopus citations

Susceptibility and resistance to antigen-induced apoptosis in the thymus of transgenic mice

Tarazona, R., Williams, O., Moskophidis, D., Smyth, L. A., Tanaka, Y., Murdjeva, M., Wack, A., Mamalaki, C. & Kioussis, D., Jun 1 1998, In : Journal of Immunology. 160, 11, p. 5397-5403 7 p.

Research output: Contribution to journalArticle

19 Scopus citations
1997

Virus-Specific IgD in Acute Viral Infection of Mice

Moskophidis, D., Moskophidis, M. & Löhler, J., Feb 1 1997, In : Journal of Immunology. 158, 3, p. 1254-1261 8 p.

Research output: Contribution to journalArticle

11 Scopus citations
1995

Immumobiology of cytotoxic T-cell escape mutants of lymphocytic choriomeningitis virus

Moskofidis, D. & Zinkernagel, R. M., Apr 1 1995, In : Journal of Virology. 69, 4, p. 2187-2193 7 p.

Research output: Contribution to journalArticle

77 Scopus citations

Role of virus and host variables in virus persistence or immunopathological disease caused by a non-cytolytic virus

Moskophidis, D., Battegay, M., Van den Broek, M., Laine, E., Hoffmann-Rohrer, U. & Zinkernagel, R. M., Jan 1 1995, In : Journal of General Virology. 76, 2, p. 381-391 11 p.

Research output: Contribution to journalArticle

67 Scopus citations
1994

Functional commitment to helper T cell lineage precedes positive selection and is independent of T cell receptor MHC specificity

Corbella, P., Moskophidis, D., Spanopoulou, E., Mamalaki, C., Tolaini, M., Itano, A., Lans, D., Baltimore, D., Robeyj, E. & Kioussis, D., Jul 1994, In : Immunity. 1, 4, p. 269-276 8 p.

Research output: Contribution to journalArticle

71 Scopus citations

MHC class I and non-MHC-linked capacity for generating an anti-viral CTL response determines susceptibility to CTL exhaustion and establishment of virus persistence in mice

Moskophidis, D., Lechner, F., Hengartner, H. & Zinkernagel, R. M., Jan 1 1994, In : Journal of Immunology. 152, 10, p. 4976-4983 8 p.

Research output: Contribution to journalArticle

51 Scopus citations

Resistance of lymphocytic choriomeningitis virus to alpha/beta interferon and to gamma interferon

Moskophidis, D., Battegay, M., Bruendler, M. A., Laine, E., Gresser, I. & Zinkernagel, R. M., Mar 1 1994, In : Journal of Virology. 68, 3, p. 1951-1955 5 p.

Research output: Contribution to journalArticle

80 Scopus citations
1993

Effector T‐Cell Induction and T‐Cell Memory versus Peripheral Deletion of T Cells

Zinkernagel, R. M., Moskofidis, D., Kündig, T., Oehen, S., Pircher, H. & Hengartner, H., Jan 1 1993, In : Immunological Reviews. 133, 1, p. 199-223 25 p.

Research output: Contribution to journalArticle

76 Scopus citations

Impairment and delay of neutralizing antiviral antibody responses by virus-specific cytotoxic T cells

Battegay, M., Moskofidis, D., Waldner, H., Brundler, M. A., Fung-Leung, W. P., Mak, T. W., Hengartner, H. & Zinkernagel, R. M., Jan 1 1993, In : Journal of Immunology. 151, 10, p. 5408-5415 8 p.

Research output: Contribution to journalArticle

103 Scopus citations

Peripheral clonal deletion of antiviral memory CD8+ T cells

Moskophidis, D., Laine, E. & Zinkernagel, R. M., Dec 1993, In : European Journal of Immunology. 23, 12, p. 3306-3311 6 p.

Research output: Contribution to journalArticle

80 Scopus citations

Virus persistence in acutely infected immunocompetent mice by exhaustion of antiviral cytotoxic effector T cells

Moskofidis, D., Lechner, F., Pircher, H. & Zinkernagel, R. M., Jan 1 1993, In : Nature. 362, 6422, p. 758-761 4 p.

Research output: Contribution to journalArticle

919 Scopus citations
1992

Immunosuppression by lymphocytic choriomeningitis virus infection: competent effector T and B cells but impaired antigen presentation

Althage, A., Odermatt, B., Moskophidis, D., Kündig, T., Hengartner, U. HR. H. & Zinkernagel, R. M., Jul 1992, In : European Journal of Immunology. 22, 7, p. 1803-1812 10 p.

Research output: Contribution to journalArticle

53 Scopus citations

Suppression of virus-specific antibody production by CD8+ class I- restricted antiviral cytotoxic T cells in vivo

Moskophidis, D., Pircher, H., Ciernik, I., Odermatt, B., Hengartner, H. & Zinkernagel, R. M., Jan 1 1992, In : Journal of Virology. 66, 6, p. 3661-3668 8 p.

Research output: Contribution to journalArticle

Open Access
22 Scopus citations
1991

In vitro selection of lymphocytic choriomeningitis virus escape mutants by cytotoxic T lymphocytes

Aebischer, T., Moskophidis, D., Rohrer, U. H., Zinkernagel, R. M. & Hengartner, H., Jan 1 1991, In : Proceedings of the National Academy of Sciences of the United States of America. 88, 24, p. 11047-11051 5 p.

Research output: Contribution to journalArticle

72 Scopus citations

Lower receptor avidity required for thymic clonal deletion than for effector T-cell function

Pircher, H., Rohrer, U. H., Moskofidis, D., Zinkernagel, R. M. & Hengartner, H., Jan 1 1991, In : Nature. 351, 6326, p. 482-485 4 p.

Research output: Contribution to journalArticle

251 Scopus citations

Production of random classes of immunoglobulins in brain tissue during persistent viral infection paralleled by secretion of interleukin-6 (IL-6) but not IL-4, IL-5, and gamma interferon

Moskophidis, D., Frei, K., Lohler, J., Fontana, A. & Zinkernagel, R. M., Jan 1 1991, In : Journal of Virology. 65, 3, p. 1364-1369 6 p.

Research output: Contribution to journalArticle

28 Scopus citations
1990

Viral escape by selection of cytotoxic T cell-resistant virus variants in vivo

Pircher, H., Moskofidis, D., Rohrer, U., Bürki, K., Hengartner, H. & Zinkernagel, R. M., Jan 1 1990, In : Nature. 346, 6285, p. 629-633 5 p.

Research output: Contribution to journalArticle

451 Scopus citations

Virus-specific delayed-type hypersensitivity (DTH). Cells mediating lymphocytic choriomeningitis virus-specific DTH reaction in mice

Moskophidis, D., Fang, L., Gossmann, J., Drjupin, R., Lohler, J., Bruns, M. & Lehmann-Grube, F., Jan 1 1990, In : Journal of Immunology. 144, 5, p. 1926-1934 9 p.

Research output: Contribution to journalArticle

15 Scopus citations
1989

Enumeration of single IFN-γ-producing cells in mice during viral and bacterial infection

Gessner, A., Moskofidis, D. & Lehmann-Grube, F., Jan 1 1989, In : Journal of Immunology. 142, 4, p. 1293-1298 6 p.

Research output: Contribution to journalArticle

43 Scopus citations

Lymphocytic choriomeningitis virus-specific delayed-type hypersensitivity reaction in mice

Lehmann-Grube, F. & Moskofidis, D., Dec 1 1989, In : Advances in Experimental Medicine and Biology. 257, p. 91-107 17 p.

Research output: Contribution to journalArticle

1 Scopus citations
7 Scopus citations