• 1011 Citations
  • 18 h-Index
20042019
If you made any changes in Pure, your changes will be visible here soon.

Research Output 2004 2019

  • 1011 Citations
  • 18 h-Index
  • 38 Article
  • 9 Review article
  • 3 Chapter
  • 1 Comment/debate
2019

Atorvastatin inhibits pro-inflammatory actions of aldosterone in vascular smooth muscle cells by reducing oxidative stress

Bruder-Nascimento, T., Callera, G. E., Montezano, A. C., Belin de Chantemele, E. J., Tostes, R. C. & Touyz, R. M., Mar 15 2019, In : Life sciences. 221, p. 29-34 6 p.

Research output: Contribution to journalArticle

Open Access
Oxidative stress
Aldosterone
Vascular Smooth Muscle
Smooth Muscle Myocytes
Muscle
3 Citations (Scopus)

Leptin and Aldosterone

Faulkner, J. L. & Belin de Chantemele, E. J., Jan 1 2019, Vitamins and Hormones. Litwack, G. (ed.). Academic Press Inc., p. 265-284 20 p. (Vitamins and Hormones; vol. 109).

Research output: Chapter in Book/Report/Conference proceedingChapter

Leptin
Aldosterone
Obesity
Hypertension
Adipose Tissue

Leptin Restores Endothelial Function via Endothelial PPARγ-Nox1-Mediated Mechanisms in a Mouse Model of Congenital Generalized Lipodystrophy

Bruder-Nascimento, T., Faulkner, J. L., Haigh, S., Kennard, S., Antonova, G., Patel, V. S., Fulton, D. J. R., Chen, W. & Belin de Chantemèle, E. J., Dec 1 2019, In : Hypertension (Dallas, Tex. : 1979). 74, 6, p. 1399-1408 10 p.

Research output: Contribution to journalArticle

Congenital Generalized Lipodystrophy
Peroxisome Proliferator-Activated Receptors
Leptin
Blood Vessels
Leptin Receptors

Mineralocorticoid Receptor and Endothelial Dysfunction in Hypertension

Faulkner, J. L. & Belin de Chantemèle, E. J., Oct 1 2019, In : Current Hypertension Reports. 21, 10, 78.

Research output: Contribution to journalReview article

Mineralocorticoid Receptors
Hypertension
Progesterone Receptors
Obesity
Epithelial Sodium Channels

Perivascular Adipocytes in Vascular Disease

Kim, H. W., Belin de Chantemèle, E. J. & Weintraub, N. L., Nov 1 2019, In : Arteriosclerosis, thrombosis, and vascular biology. 39, 11, p. 2220-2227 8 p.

Research output: Contribution to journalArticle

Open Access
Vascular Diseases
Adipocytes
Blood Vessels
White Adipocytes
Brown Adipocytes
1 Citation (Scopus)

Progesterone predisposes females to obesity-associated leptin-mediated endothelial dysfunction via upregulating endothelial mr (mineralocorticoid receptor) expression

Faulkner, J. L., Kennard, S., Huby, A. C., Antonova, G., Lu, Q., Jaffe, I. Z., Patel, V. S., Fulton, D. J. R. & Belin De Chantemèle, E. J., Sep 1 2019, In : Hypertension. 74, 3, p. 678-686 9 p.

Research output: Contribution to journalArticle

Mineralocorticoid Receptors
Leptin
Progesterone
Obesity
Progesterone Receptors
Open Access
Lipodystrophy
Peer Review
Leptin
Cardiovascular Diseases
Medical problems

Sex hormones, aging and cardiometabolic syndrome

Faulkner, J. L. & Belin De Chantemèle, E. J., Jul 1 2019, In : Biology of Sex Differences. 10, 1, 30.

Research output: Contribution to journalReview article

Open Access
Gonadal Steroid Hormones
Sex Chromosomes
Sex Characteristics
Homeostasis
Obesity
2018
3 Citations (Scopus)

Identification of novel macropinocytosis inhibitors using a rational screen of Food and Drug Administration-approved drugs

Lin, H. P., Singla, B., Ghoshal, P., Faulkner, J. L., Cherian-Shaw, M., O'Connor, P. M., She, J. X., Belin de Chantemele, E. J. & Csányi, G., Sep 2018, In : British Journal of Pharmacology. 175, 18, p. 3640-3655 16 p.

Research output: Contribution to journalArticle

Imipramine
United States Food and Drug Administration
Pharmaceutical Preparations
Endocytosis
Electron Scanning Microscopy
1 Citation (Scopus)

Lack of suppression of aldosterone production leads to salt-sensitive hypertension in female but not Male BALB/c mice

Faulkner, J. L., Harwood, D., Bender, L., Shrestha, L., Brands, M. W., Jane Morwitzer, M., Kennard, S., Antonova, G. & Belin De Chantemèle, E. J., Dec 2018, In : Hypertension. 72, 6, p. 1397-1406 10 p.

Research output: Contribution to journalArticle

Aldosterone
Salts
Hypertension
Mineralocorticoid Receptors
Diet
4 Citations (Scopus)

New roles of aldosterone and mineralocorticoid receptors in cardiovascular disease: Translational and sex-specific effects

Davel, A. P., Jaffe, I. Z., Tostes, R. C., Jaisser, F. & Belin de Chantemele, E. J., Oct 1 2018, In : American Journal of Physiology - Heart and Circulatory Physiology. 315, 4, p. H989-H999

Research output: Contribution to journalReview article

Mineralocorticoid Receptors
Aldosterone
Cardiovascular Diseases
Obesity
Leptin
3 Citations (Scopus)

Remote Effects of Transplanted Perivascular Adipose Tissue on Endothelial Function and Atherosclerosis

Horimatsu, T., Patel, A. S., Prasad, R., Reid, L. E., Benson, T. W., Zarzour, A., Ogbi, M., Bruder do Nascimento, T., Belin de Chantemele, E., Stansfield, B. K., Lu, X. Y., Kim, H. W. & Weintraub, N. L., Oct 1 2018, In : Cardiovascular Drugs and Therapy. 32, 5, p. 503-510 8 p.

Research output: Contribution to journalArticle

Adipose Tissue
Atherosclerosis
Tissue Transplantation
Abdominal Aorta
Obesity
21 Citations (Scopus)

Sex Differences in Mechanisms of Hypertension Associated with Obesity

Faulkner, J. L. & Belin De Chantemèle, E. J., Jan 1 2018, In : Hypertension. 71, 1, p. 15-21 7 p.

Research output: Contribution to journalReview article

Sex Factors
Age Factors
Sympathetic Nervous System
Renin-Angiotensin System
Sex Characteristics
10 Citations (Scopus)

The regulation of aldosterone secretion by leptin: Implications in obesity-related cardiovascular disease

Faulkner, J. L., Bruder-Nascimento, T. & Belin De Chantemèle, E. J., Mar 1 2018, In : Current opinion in nephrology and hypertension. 27, 2, p. 63-69 7 p.

Research output: Contribution to journalReview article

Leptin
Aldosterone
Cardiovascular Diseases
Obesity
Adipocytes
2017
11 Citations (Scopus)

Genetic deletion of NADPH oxidase 1 rescues microvascular function in mice with metabolic disease

Thompson, J. A., Larion, S., Mintz, J. D., Belin De Chantemèle, E. J., Fulton, D. J. & Stepp, D. W., Aug 1 2017, In : Circulation research. 121, 5, p. 502-511 10 p.

Research output: Contribution to journalArticle

Metabolic Diseases
Acetylcholine
Reactive Oxygen Species
Blood Vessels
Mesenteric Arteries
11 Citations (Scopus)

Long term high fat diet treatment: An appropriate approach to study the sex-specificity of the autonomic and cardiovascular responses to obesity in mice

Bruder-Nascimento, T., Ekeledo, O. J., Anderson, R., Le, H. B. & Belin de Chantemele, E. J., Jan 1 2017, In : Frontiers in Physiology. 8, JAN, 32.

Research output: Contribution to journalArticle

High Fat Diet
Obesity
Heart Rate
Blood Vessels
Therapeutics
5 Citations (Scopus)

Sex differences in leptin control of cardiovascular function in health and metabolic diseases

Belin de Chantemele, E. J., Jan 1 2017, Advances in Experimental Medicine and Biology. Springer New York LLC, p. 87-111 25 p. (Advances in Experimental Medicine and Biology; vol. 1043).

Research output: Chapter in Book/Report/Conference proceedingChapter

Metabolic Diseases
Leptin
Sex Characteristics
Health
Adipose Tissue
2016
53 Citations (Scopus)

Leptin induces hypertension and endothelial dysfunction via aldosterone-dependent mechanisms in obese female mice

Huby, A. C., Otvos, L. & De Chantemèle, E. J. B., May 1 2016, In : Hypertension. 67, 5, p. 1020-1028 9 p.

Research output: Contribution to journalArticle

Obese Mice
Leptin
Aldosterone
Hypertension
Obesity
4 Citations (Scopus)

Ptp1b deletion in pro-opiomelanocortin neurons increases energy expenditure and impairs endothelial function via TNF-α dependent mechanisms

Bruder-Nascimento, T., Kennard, S., Antonova, G., Mintz, J. D., Bence, K. K. & Belin de Chantemele, E. J., Jan 1 2016, In : Clinical Science. 130, 11, p. 881-893 13 p.

Research output: Contribution to journalArticle

Non-Receptor Type 1 Protein Tyrosine Phosphatase
Pro-Opiomelanocortin
Energy Metabolism
Tumor Necrosis Factor-alpha
Neurons
2015
97 Citations (Scopus)

Adipocyte-Derived Hormone Leptin Is a Direct Regulator of Aldosterone Secretion, Which Promotes Endothelial Dysfunction and Cardiac Fibrosis

Huby, A. C., Antonova, G., Groenendyk, J., Gomez-Sanchez, C. E., Bollag, W. B., Filosa, J. A. & De Chantemèle, E. J. B., Dec 1 2015, In : Circulation. 132, 22, p. 2134-2145 12 p.

Research output: Contribution to journalArticle

Cytochrome P-450 CYP11B2
Leptin
Aldosterone
Adipocytes
Fibrosis
4 Citations (Scopus)

Correction: Deletion of protein tyrosine phosphatase 1B (PTP1B) enhances endothelial cyclooxygenase 2 expression and protects mice from type 1 diabetes-induced endothelial dysfunction

Herren, D. J., Norman, J. B., Anderson, R., Tremblay, M. L., Huby, A. C. & Belin De Chantemèle, E. J., Jun 11 2015, In : PloS one. 10, 6, e0130781.

Research output: Contribution to journalComment/debate

Non-Receptor Type 1 Protein Tyrosine Phosphatase
protein-tyrosine-phosphatase
insulin-dependent diabetes mellitus
prostaglandin synthase
Cyclooxygenase 2
15 Citations (Scopus)

Deletion of protein tyrosine phosphatase 1B (PTP1B) enhances endothelial cyclooxygenase 2 expression and protects mice from type 1 diabetes-induced endothelial dysfunction

Herre, D. J., Norman, J. B., Anderson, R., Tremblay, M. L., Huby, A. C. & Belin de Chantemele, E. J., May 14 2015, In : PloS one. 10, 5, e0126866.

Research output: Contribution to journalArticle

Non-Receptor Type 1 Protein Tyrosine Phosphatase
protein-tyrosine-phosphatase
insulin-dependent diabetes mellitus
prostaglandin synthase
Cyclooxygenase 2
6 Citations (Scopus)
Non-Receptor Type 1 Protein Tyrosine Phosphatase
Pro-Opiomelanocortin
Leptin
Blood Pressure
Hypertension
4 Citations (Scopus)
Aldosterone
Obesity
Hypertension
Antihypertensive Agents
Blood Pressure
9 Citations (Scopus)

The adipokine leptin mediates muscle- and liver-derived IGF-1 in aged mice

Hamrick, M. W., Dukes, A., Arounleut, P., Davis, C. M., Periyasamy Thandavan, S., Mork, S., Herberg, S., Johnson, M. H., Isales, C. M., Hill, W. D., Otvos, L. & Belin de Chantemele, E. J., Oct 1 2015, In : Experimental Gerontology. 70, p. 92-96 5 p.

Research output: Contribution to journalArticle

Adipokines
Leptin
Insulin-Like Growth Factor I
Liver
Muscle
2014
61 Citations (Scopus)
Caveolae
Peroxynitrous Acid
Arterioles
Dilatation
Diabetes Mellitus
2013
7 Citations (Scopus)

Cyclooxygenase-2-derived prostanoids reduce inward arterial remodeling induced by blood flow reduction in old obese Zucker rat mesenteric arteries

Vessières, E., Belin de Chantemele, E. J., Guihot, A. L., Jardel, A., Toutain, B., Loufrani, L. & Henrion, D., May 1 2013, In : Vascular Pharmacology. 58, 5-6, p. 356-362 7 p.

Research output: Contribution to journalArticle

Zucker Rats
Mesenteric Arteries
Cyclooxygenase 2
Prostaglandins
Arteries

PTP1B in obesity-related cardiovascular function

Ketsawatsomkron, P., Stepp, D. W. & De Chantemèle, E. J. B., Apr 1 2013, Protein Tyrosine Phosphatase Control of Metabolism. Springer New York, p. 129-145 17 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Non-Receptor Type 1 Protein Tyrosine Phosphatase
Obesity
Cardiovascular system
Cardiovascular System
Animals
11 Citations (Scopus)

Vascular effects of deletion of melanocortin-4 receptors in rats

Stepp, D. W., Osakwe, C. C., de Chantemele, E. J. B. & Mintz, J. D., Jan 1 2013, In : Physiological reports. 1, 6, p. 1-7 7 p., e00146.

Research output: Contribution to journalArticle

Receptor, Melanocortin, Type 4
Blood Vessels
Obesity
Hypertension
Insulin
2012
19 Citations (Scopus)

Increasing peripheral insulin sensitivity by protein tyrosine phosphatase 1B deletion improves control of blood pressure in obesity

De Chantemèle, E. J. B., Ali, M. I., Mintz, J. D., Rainey, W. E., Tremblay, M. L., Fulton, D. J. & Stepp, D. W., Nov 1 2012, In : Hypertension. 60, 5, p. 1273-1279 7 p.

Research output: Contribution to journalArticle

Non-Receptor Type 1 Protein Tyrosine Phosphatase
Insulin Resistance
Obesity
Blood Pressure
Hypertension
32 Citations (Scopus)
Coronary Circulation
Obesity
Blood Vessels
Vascular Endothelium
Hemostasis
2011
60 Citations (Scopus)

Impact of leptin-mediated sympatho-activation on cardiovascular function in obese mice

De Chantemèle, E. J. B., Mintz, J. D., Rainey, W. E. & Stepp, D. W., Aug 1 2011, In : Hypertension. 58, 2, p. 271-279 9 p.

Research output: Contribution to journalArticle

Obese Mice
Leptin
High Fat Diet
Obesity
Aldosterone
2010
23 Citations (Scopus)

Cyclooxygenase-2 inhibition restored endothelium-mediated relaxation in old obese Zucker rat mesenteric arteries

Vessières, E., Belin de Chantemèle, E. J., Toutain, B., Guihot, A. L., Jardel, A., Loufrani, L. & Henrion, D., Dec 1 2010, In : Frontiers in Physiology. 1 NOV, 145.

Research output: Contribution to journalArticle

Zucker Rats
Mesenteric Arteries
Cyclooxygenase 2
Endothelium
Prostaglandins
18 Citations (Scopus)

Cyclooxygenase-2 preserves flow-mediated remodelling in old obese zucker rat mesenteric arteries

Belin De Chantemle, E. J., Vessires, E., Guihot, A. L., Toutain, B., Loufrani, L. & Henrion, D., Jun 1 2010, In : Cardiovascular Research. 86, 3, p. 516-525 10 p.

Research output: Contribution to journalArticle

Zucker Rats
Mesenteric Arteries
Cyclooxygenase 2
Arteries
Acetylcholine
32 Citations (Scopus)

Reactive oxygen species and cyclooxygenase 2-derived thromboxane A2 reduce angiotensin II type 2 receptor vasorelaxation in diabetic rat resistance arteries

Retailleau, K., Belin De Chantemèle, E. J., Chanoine, S., Guihot, A. L., Vessières, E., Toutain, B., Faure, S., Bagi, Z., Loufrani, L. & Henrion, D., Feb 1 2010, In : Hypertension. 55, 2, p. 339-344 6 p.

Research output: Contribution to journalArticle

Angiotensin Type 2 Receptor
Thromboxane A2
Cyclooxygenase 2
Vasodilation
Reactive Oxygen Species
2009
58 Citations (Scopus)

Deletion of protein tyrosine phosphatase 1b improves peripheral insulin resistance and vascular function in obese, leptin-resistant mice via reduced oxidant tone

Ali, M. I., Ketsawatsomkron, P., Belin De Chantemele, E. J., Mintz, J. D., Muta, K., Salet, C., Black, S. M., Tremblay, M. L., Fulton, D. J., Marrero, M. B. & Stepp, D. W., Nov 1 2009, In : Circulation research. 105, 10, p. 1013-1022 10 p.

Research output: Contribution to journalArticle

Non-Receptor Type 1 Protein Tyrosine Phosphatase
Leptin
Oxidants
Vascular Resistance
Blood Vessels
15 Citations (Scopus)

Effects of immersion in water containing high concentrations of CO 2 (CO2-water) at thermoneutral on thermoregulation and heart rate variability in humans

Sato, M., Kanikowska, D., Iwase, S., Nishimura, N., Shimizu, Y., De Chantemele, E. B., Matsumoto, T., Inukai, Y., Taniguchi, Y., Ogata, A. & Sugenoya, J., Jan 1 2009, In : International Journal of Biometeorology. 53, 1, p. 25-30 6 p.

Research output: Contribution to journalArticle

thermoregulation
Body Temperature Regulation
Immersion
Carbon Monoxide
Heart Rate
16 Citations (Scopus)
Hindlimb
Blood Vessels
Insulin Resistance
Ischemia
Obesity
41 Citations (Scopus)

Protein tyrosine phosphatase 1B, a major regulator of leptin-mediated control of cardiovascular function

De Belin Chantemèle, E. J., Muta, K., Mintz, J., Tremblay, M. L., Matrero, M. B., Fulton, D. J. & Stepp, D. W., Nov 12 2009, In : Circulation. 120, 9, p. 753-763 11 p.

Research output: Contribution to journalArticle

Non-Receptor Type 1 Protein Tyrosine Phosphatase
Leptin
Knockout Mice
Arterial Pressure
Phenylephrine
30 Citations (Scopus)

Reactive oxygen species are necessary for high flow (shear Stress)-induced diameter enlargement of rat resistance arteries

Belin De Chanteméle, E., Vessiéres, E., Dumont, O., Guihot, A. L., Toutain, B., Loufrani, L. & Henrion, D., Aug 12 2009, In : Microcirculation. 16, 5, p. 391-402 12 p.

Research output: Contribution to journalArticle

Reactive Oxygen Species
Arteries
Endothelium
Peroxynitrous Acid
Mesenteric Arteries
37 Citations (Scopus)

Type 2 diabetes severely impairs structural and functional adaptation of rat resistance arteries to chronic changes in blood flow

Belin De Chantemèle, E. J., Vessières, E., Guihot, A. L., Toutain, B., Maquignau, M., Loufrani, L. & Henrion, D., Mar 1 2009, In : Cardiovascular Research. 81, 4, p. 788-796 9 p.

Research output: Contribution to journalArticle

Type 2 Diabetes Mellitus
Arteries
Dilatation
Zucker Rats
Superoxides
2008
2 Citations (Scopus)

CGP12177-induced haemodynamic and vascular effects in normotensive and hypertensive rats

Holopherne, D., Mallem, M. Y., Le Strat, E., de Chantemèle, E. J. B., Gogny, M., Henrion, D., Noireaud, J. & Desfontis, J. C., Sep 4 2008, In : European Journal of Pharmacology. 591, 1-3, p. 196-202 7 p.

Research output: Contribution to journalArticle

Inbred WKY Rats
Inbred SHR Rats
Blood Vessels
Hemodynamics
Adrenergic Receptors
63 Citations (Scopus)

Notch3 is a major regulator of vascular tone in cerebral and tail resistance arteries

Belin De Chantemèle, E. J., Retailleau, K., Pinaud, F., Vessières, E., Bocquet, A., Guihot, A. L., Lemaire, B., Domenga, V., Baufreton, C., Loufrani, L., Joutel, A. & Henrion, D., Dec 2008, In : Arteriosclerosis, thrombosis, and vascular biology. 28, 12, p. 2216-2224 9 p.

Research output: Contribution to journalArticle

Blood Vessels
Tail
Arteries
Dilatation
rho-Associated Kinases
68 Citations (Scopus)

Paradoxical activation of endothelial nitric oxide synthase by NADPH oxidase

Zhang, Q., Malik, P., Pandey, D., Gupta, S., Jagnandan, D., De Chantemele, E. B., Banfi, B., Marrero, M. B., Rudic, R. D., Stepp, D. W. & Fulton, D. J. R., Sep 1 2008, In : Arteriosclerosis, thrombosis, and vascular biology. 28, 9, p. 1627-1633 7 p.

Research output: Contribution to journalArticle

Nitric Oxide Synthase Type III
NADPH Oxidase
Reactive Oxygen Species
Blood Vessels
Superoxides
2007
61 Citations (Scopus)

Flow-induced remodeling in resistance arteries from obese Zucker rats is associated with endothelial dysfunction

Bouvet, C., De Chantemèle, E. B., Guihot, A. L., Vessières, E., Bocquet, A., Dumont, O., Jardel, A., Loufrani, L., Moreau, P. & Henrion, D., Jul 1 2007, In : Hypertension. 50, 1, p. 248-254 7 p.

Research output: Contribution to journalArticle

Zucker Rats
Arteries
Endothelium
Dilatation
Superoxides
14 Citations (Scopus)

Structural remodeling in the limb circulation: Impact of obesity and diabetes

Stepp, D. W. & Belin de Chantemele, E. J., Jun 1 2007, In : Microcirculation. 14, 4-5, p. 311-316 6 p.

Research output: Contribution to journalReview article

Microcirculation
Extremities
Obesity
Basement Membrane
Type 2 Diabetes Mellitus
2006
14 Citations (Scopus)

Blood volume measurement: The comparison of pulse dye densitometry and Dill and Costill's methods

Belin De Chantemèle, E., Gauquelin-Koch, G., Duvareille, M., Pellet, N., Gharib, C. & Custaud, M. A., Feb 28 2006, In : Life sciences. 78, 14, p. 1564-1569 6 p.

Research output: Contribution to journalArticle

Anethum graveolens
Volume measurement
Densitometry
Blood Volume
Blood
2005
4 Citations (Scopus)

Régulation de la volémie au cours d'une simulation d'impesanteur de longue durée

Translated title of the contribution: Regulation of volemia during a prolonged weightlessness simulationCustaud, M. A., Belin de Chantemele, E. J., Blanc, S., Gauquelin-Koch, G. & Gharib, C., Dec 1 2005, In : Canadian Journal of Physiology and Pharmacology. 83, 12, p. 1147-1153 7 p.

Research output: Contribution to journalArticle

Weightlessness Simulation
Diuretics
Plasma Volume
Hormones
Body Water
2004
24 Citations (Scopus)

Calf venous volume during stand-test after a 90-day bed-rest study with or without exercise countermeasure

Belin de Chantemèle, E., Pascaud, L., Custaud, M. A., Capri, A., Louisy, F., Ferretti, G., Gharib, C. & Arbeille, P., Dec 1 2004, In : Journal of Physiology. 561, 2, p. 611-622 12 p.

Research output: Contribution to journalArticle

Bed Rest
Orthostatic Intolerance
Posture
Veins
Head-Down Tilt
24 Citations (Scopus)

Does resistance exercise prevent body fluid changes after a 90-day bed rest?

Belin de Chantemele, E., Blanc, S., Pellet, N., Duvareille, M., Ferretti, G., Gauquelin-Koch, G., Gharib, C. & Custaud, M. A., Aug 1 2004, In : European Journal of Applied Physiology. 92, 4-5, p. 555-564 10 p.

Research output: Contribution to journalArticle

Bed Rest
Cardiovascular Deconditioning
Body Fluids
Atrial Natriuretic Factor
Aldosterone