• 12253 Citations
  • 56 h-Index
1973 …2020

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Research Output

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Article
2012

Novel toll-like receptor 2 ligands for targeted pancreatic cancer imaging and immunotherapy

Huynh, A. S., Chung, W. J., Cho, H. I., Moberg, V. E., Celis, E., Morse, D. L. & Vagner, J., Nov 26 2012, In : Journal of Medicinal Chemistry. 55, 22, p. 9751-9762 12 p.

Research output: Contribution to journalArticle

21 Scopus citations

Vaccine-elicited CD8+T cells protect against respiratory syncytial virus strain A2-line19F-induced pathogenesis in BALB/c mice

Lee, S., Stokes, K. L., Currier, M. G., Sakamoto, K., Lukacs, N. W., Celis, E. & Moore, M. L., Dec 2012, In : Journal of Virology. 86, 23, p. 13016-13024 9 p.

Research output: Contribution to journalArticle

35 Scopus citations
2011

Interferon γ limits the effectiveness of melanoma peptide vaccines

Cho, H. I., Lee, Y. R. & Celis, E., Jan 6 2011, In : Blood. 117, 1, p. 135-144 10 p.

Research output: Contribution to journalArticle

42 Scopus citations

Six-transmembrane epithelial antigen of the prostate and enhancer of zeste homolog 2 as immunotherapeutic targets for lung cancer

Hayashi, S., Kumai, T., Matsuda, Y., Aoki, N., Sato, K., Kimura, S., Kitada, M., Tateno, M., Celis, E. & Kobayashi, H., Nov 5 2011, In : Journal of Translational Medicine. 9, 1, 191.

Research output: Contribution to journalArticle

25 Scopus citations

Tumor-infiltrating myeloid cells induce tumor cell resistance to cytotoxic T cells in mice

Lu, T., Ramakrishnan, R., Altiok, S., Youn, J. I., Cheng, P., Celis, E., Pisarev, V., Sherman, S., Sporn, M. B. & Gabrilovich, D., Oct 3 2011, In : Journal of Clinical Investigation. 121, 10, p. 4015-4029 15 p.

Research output: Contribution to journalArticle

195 Scopus citations
2010

Characterization of human CD4 helper T cell responses against Aurora kinase A

Kobayashi, H., Azumi, M., Hayashi, S., Sato, K., Aoki, N., Kimura, S., Kakizaki, H., Nagato, T., Harabuchi, Y., Tateno, M. & Celis, E., Jul 1 2010, In : Cancer Immunology, Immunotherapy. 59, 7, p. 1029-1039 11 p.

Research output: Contribution to journalArticle

4 Scopus citations

Chemotherapy enhances tumor cell susceptibility to CTL-mediated killing during cancer immunotherapy in mice

Ramakrishnan, R., Assudani, D., Nagaraj, S., Hunter, T., Cho, H. I., Antonia, S., Altiok, S., Celis, E. & Gabrilovich, D. I., Apr 1 2010, In : Journal of Clinical Investigation. 120, 4, p. 1111-1124 14 p.

Research output: Contribution to journalArticle

294 Scopus citations

Combination cytokine therapy inhibits tumor growth by generation of tumor-specific T-cell responses in a murine melanoma model

Kalaaji, A. N., Lu, J., Markovic, S. N., Celis, E. & Pittelkow, M. R., Mar 1 2010, In : Cytokine. 49, 3, p. 287-293 7 p.

Research output: Contribution to journalArticle

3 Scopus citations

HIF-1α regulates function and differentiation of myeloid-derived suppressor cells in the tumor microenvironment

Corzo, C. A., Condamine, T., Lu, L., Cotter, M. J., Youn, J. I., Cheng, P., Cho, H. I., Celis, E., Quiceno, D. G., Padhya, T., McCaffrey, T. V., McCaffrey, J. C. & Gabrilovich, D. I., Oct 25 2010, In : Journal of Experimental Medicine. 207, 11, p. 2439-2453 15 p.

Research output: Contribution to journalArticle

589 Scopus citations

Lipid accumulation and dendritic cell dysfunction in cancer

Herber, D. L., Cao, W., Nefedova, Y., Novitskiy, S. V., Nagaraj, S., Tyurin, V. A., Corzo, A., Cho, H. I., Celis, E., Lennox, B., Knight, S. C., Padhya, T., McCaffrey, T. V., McCaffrey, J. C., Antonia, S., Fishman, M., Ferris, R. L., Kagan, V. E. & Gabrilovich, D. I., Aug 2010, In : Nature Medicine. 16, 8, p. 880-886 7 p.

Research output: Contribution to journalArticle

261 Scopus citations

Mechanism of T cell tolerance induced by myeloid-derived suppressor cells

Nagaraj, S., Schrum, A. G., Cho, H. I., Celis, E. & Gabrilovich, D. I., Mar 15 2010, In : Journal of Immunology. 184, 6, p. 3106-3116 11 p.

Research output: Contribution to journalArticle

242 Scopus citations

Optimized combination therapy using bortezomib, TRAIL and TLR agonists in established breast tumors

Lee, S., Yagita, H., Sayers, T. J. & Celis, E., Jul 2010, In : Cancer Immunology, Immunotherapy. 59, 7, p. 1073-1081 9 p.

Research output: Contribution to journalArticle

12 Scopus citations

PRDM1/Blimp-1 controls effector cytokine production in human NK cells

Smith, M. A., Maurin, M., Cho, H. I., Becknell, B., Freud, A. G., Yu, J., Wei, S., Djeu, J., Celis, E., Caligiuri, M. A. & Wright, K. L., Nov 15 2010, In : Journal of Immunology. 185, 10, p. 6058-6067 10 p.

Research output: Contribution to journalArticle

55 Scopus citations
2009

Focal adhesion kinase as an immunotherapeutic target

Kobayashi, H., Azumi, M., Kimura, Y., Sato, K., Aoki, N., Kimura, S., Honma, M., Iizuka, H., Tateno, M. & Celis, E., Jun 2009, In : Cancer Immunology, Immunotherapy. 58, 6, p. 931-940 10 p.

Research output: Contribution to journalArticle

3 Scopus citations

Optimized peptide vaccines eliciting extensive CD8 T-cell responses with therapeutic antitumor effects

Cho, H. I. & Celis, E., Dec 1 2009, In : Cancer Research. 69, 23, p. 9012-9019 8 p.

Research output: Contribution to journalArticle

91 Scopus citations

Oral administration of PPC enhances antigen-specific CD8+ T cell responses while reducing IgE levels in sensitized mice

Burrows, M., Assundani, D., Celis, E., Tufaro, F., Tanaka, A. & Bradley, W. G., Nov 30 2009, In : BMC Complementary and Alternative Medicine. 9, 49.

Research output: Contribution to journalArticle

7 Scopus citations

PKCθ is required for alloreactivity and GVHD but not for immune responses toward leukemia and infection in mice

Valenzuela, J. O., Iclozan, C., Hossain, M. S., Prlic, M., Hopewell, E., Bronk, C. C., Wang, J., Celis, E., Engelman, R. W., Blazar, B. R., Bevan, M. J., Waller, E. K., Yu, X. Z. & Beg, A. A., Dec 1 2009, In : Journal of Clinical Investigation. 119, 12, p. 3774-3786 13 p.

Research output: Contribution to journalArticle

57 Scopus citations

Stimulatory effects of CpG ollgodeoxynucleotide on dendritic cell-based immunotherapy of colon cancer in CEA/HLA-A2 transgenic mice

Sah, A., Bhattacharya-Chatterjee, M., Foon, K. A., Celis, E. & Chatterjee, S. K., Feb 15 2009, In : International Journal of Cancer. 124, 4, p. 877-888 12 p.

Research output: Contribution to journalArticle

21 Scopus citations
2008

Induction of EBV-latent membrane protein 1-specific MHC class II-restricted T-cell responses against natural killer lymphoma cells

Kobayashi, H., Nagato, T., Takahara, M., Sato, K., Kimura, S., Aoki, N., Azumi, M., Tateno, M., Harabuchi, Y. & Celis, E., Feb 1 2008, In : Cancer Research. 68, 3, p. 901-908 8 p.

Research output: Contribution to journalArticle

33 Scopus citations

In vivo expansion, persistence, and function of peptide vaccine-induced CD8 T cells occur independently of CD4 T cells

Assudani, D., Cho, H. I., DeVito, N., Bradley, N. & Celis, E., Dec 1 2008, In : Cancer Research. 68, 23, p. 9892-9899 8 p.

Research output: Contribution to journalArticle

45 Scopus citations

Optimized DNA vaccines to specifically induce therapeutic CD8 T cell responses against autochthonous breast tumors

Cho, H. I., Niu, G., Bradley, N. & Celis, E., Nov 2008, In : Cancer Immunology, Immunotherapy. 57, 11, p. 1695-1703 9 p.

Research output: Contribution to journalArticle

14 Scopus citations

Unpasteurized milk consumption and subsequent risk of cancer

Sellers, T. A., Vierkant, R. A., Djeu, J., Celis, E., Wang, A. H., Kumar, N. & Cerhan, J. R., Oct 2008, In : Cancer Causes and Control. 19, 8, p. 805-811 7 p.

Research output: Contribution to journalArticle

6 Scopus citations
2007

Functional analysis of birch pollen allergen Bet v 1-specific regulatory T cells

Nagato, T., Kobayashi, H., Yanai, M., Sato, K., Aoki, N., Oikawa, K., Kimura, S., Abe, Y., Celis, E., Harabuchi, Y. & Tateno, M., Jan 15 2007, In : Journal of Immunology. 178, 2, p. 1189-1198 10 p.

Research output: Contribution to journalArticle

18 Scopus citations

In vitro induction of immune responses to shared tumor-associated antigens in rhabdomyosarcoma

Rodeberg, D. A., Erskine, C. & Celis, E., Aug 1 2007, In : Journal of Pediatric Surgery. 42, 8, p. 1396-1402 7 p.

Research output: Contribution to journalArticle

9 Scopus citations

Overlapping human leukocyte antigen class I/II binding peptide vaccine for the treatment of patients with stage IV melanoma: Evidence of systemic immune dysfunction

Celis, E., Markovic, S. N., Suman, V. J., Rao, R. D., Creagan, E. T., Knutson, K. L., Leontovich, A. A., Ingle, J. N., Kaur, J. S., Erickson, L. A., Pitot, H. C., Allred, J. B., Kottschade, L. A., McWilliams, R. R., Croghan, G. A. & Nevala, W. K., Jul 1 2007, In : Cancer. 110, 1, p. 203-214 12 p.

Research output: Contribution to journalArticle

32 Scopus citations

Peptide vaccine given with a toll-like receptor agonist is effective for the treatment and prevention of spontaneous breast tumors

Nava-Parada, P., Forni, G., Knutson, K. L., Pease, L. R. & Celis, E., Feb 1 2007, In : Cancer Research. 67, 3, p. 1326-1334 9 p.

Research output: Contribution to journalArticle

93 Scopus citations

Recognition of prostate and melanoma tumor cells by six-transmembrane epithelial antigen of prostate-specific helper T lymphocytes in a human leukocyte antigen class II-restricted manner

Kobayashi, H., Nagato, T., Sato, K., Aoki, N., Kimura, S., Murakami, M., Iizuka, H., Azumi, M., Kakizaki, H., Tateno, M. & Celis, E., Jun 1 2007, In : Cancer Research. 67, 11, p. 5498-5504 7 p.

Research output: Contribution to journalArticle

24 Scopus citations

Therapy of established tumors in a novel murine model transgenic for human carcinoembryonic antigen and HLA-A2 with a combination of anti-idiotype vaccine and CTL peptides of carcinoembryonic antigen

Saha, A., Chatterjee, S. K., Foon, K. A., Celis, E. & Bhattacharya-Chatterjee, M., Mar 15 2007, In : Cancer Research. 67, 6, p. 2881-2892 12 p.

Research output: Contribution to journalArticle

26 Scopus citations
2006

A reproducible method for the enumeration of functional (cytokine producing) versus non-functional peptide-specific cytotoxic T lymphocytes in human peripheral blood

Markovic, S. N., Nevala, W. K., Uhl, C. B., Celis, E. & McKean, D. J., Sep 2006, In : Clinical and Experimental Immunology. 145, 3, p. 438-447 10 p.

Research output: Contribution to journalArticle

9 Scopus citations

Defining MHC class II T helper epitopes for WT1 tumor antigen

Kobayashi, H., Nagato, T., Aoki, N., Sato, K., Kimura, S., Tateno, M. & Celis, E., Jul 2006, In : Cancer Immunology, Immunotherapy. 55, 7, p. 850-860 11 p.

Research output: Contribution to journalArticle

35 Scopus citations

Generation of tumoricidal PAX3 peptide antigen specific cytotoxic T lymphocytes

Rodeberg, D. A., Nuss, R. A., Elsawa, S. F., Erskine, C. L. & Celis, E., Jul 1 2006, In : International Journal of Cancer. 119, 1, p. 126-132 7 p.

Research output: Contribution to journalArticle

7 Scopus citations

In vitro peptide immunization of target tax protein human T-cell leukemia virus type 1-specific CD4+ helper T lymphocytes

Kobayashi, H., Ngato, T., Sato, K., Aoki, N., Kimura, S., Tanaka, Y., Aizawa, H., Tateno, M. & Celis, E., Jun 15 2006, In : Clinical Cancer Research. 12, 12, p. 3814-3822 9 p.

Research output: Contribution to journalArticle

10 Scopus citations

Peptide vaccination of patients with metastatic melanoma: Improved clinical outcome in patients demonstrating effective immunization

Markovic, S. N., Suman, V. J., Ingle, J. N., Kaur, J. S., Pitot, H. C., Loprinzi, C. L., Rao, R. D., Creagan, E. T., Pittelkow, M. R., Allred, J. B., Nevala, W. K. & Celis, E., Aug 1 2006, In : American Journal of Clinical Oncology: Cancer Clinical Trials. 29, 4, p. 352-360 9 p.

Research output: Contribution to journalArticle

48 Scopus citations

T helper lymphocytes rescue CTL from activation-induced cell death

Kennedy, R. & Celis, E., Sep 1 2006, In : Journal of Immunology. 177, 5, p. 2862-2872 11 p.

Research output: Contribution to journalArticle

47 Scopus citations
2005

Direct cross-priming by Th lymphocytes generates memory cytotoxic T cell responses

Kennedy, R., Undale, A. H., Kieper, W. C., Block, M. S., Pease, L. R. & Celis, E., Apr 1 2005, In : Journal of Immunology. 174, 7, p. 3967-3977 11 p.

Research output: Contribution to journalArticle

25 Scopus citations

Lack of effective T-lymphocyte response to the PAX3/FKHR translocation area in alveolar rhabdomyosarcoma

Rodeberg, D. A., Nuss, R. A., Heppelmann, C. J. & Celis, E., Jun 2005, In : Cancer Immunology, Immunotherapy. 54, 6, p. 526-534 9 p.

Research output: Contribution to journalArticle

16 Scopus citations

Recognition of prostate and breast tumor cells by helper T lymphocytes specific for a prostate and breast tumor-associated antigen, TARP

Kobayashi, H., Nagato, T., Oikawa, K., Sato, K., Kimura, S., Aoki, N., Omiya, R., Tateno, M. & Celis, E., May 15 2005, In : Clinical Cancer Research. 11, 10, p. 3869-3878 10 p.

Research output: Contribution to journalArticle

28 Scopus citations

Recognition of six-transmembrane epithelial antigen of the prostate-expressing tumor cells by peptide antigen-induced cytotoxic T lymphocytes

Rodeberg, D. A., Nuss, R. A., Elsawa, S. F. & Celis, E., Jun 15 2005, In : Clinical Cancer Research. 11, 12, p. 4545-4552 8 p.

Research output: Contribution to journalArticle

41 Scopus citations

Transcutaneous immunization with cytotoxic T-cell peptide epitopes provides effective antitumor immunity in mice

Itoh, T. & Celis, E., 2005, In : Journal of Immunotherapy. 28, 5, p. 430-437 8 p.

Research output: Contribution to journalArticle

34 Scopus citations
2004

Antigen-independent acquisition of MHC class II molecules by human T lymphocytes

Undale, A. H., van den Elsen, P. J. & Celis, E., Oct 2004, In : International Immunology. 16, 10, p. 1523-1533 11 p.

Research output: Contribution to journalArticle

20 Scopus citations

Augmentation of T cell levels and responses induced by androgen deprivation

Roden, A. C., Moser, M. T., Tri, S. D., Mercader, M., Kuntz, S. M., Dong, H., Hurwitz, A. A., McKean, D. J., Celis, E., Leibovich, B. C., Allison, J. P. & Kwon, E. D., Nov 15 2004, In : Journal of Immunology. 173, 10, p. 6098-6108 11 p.

Research output: Contribution to journalArticle

177 Scopus citations

Identification and Characterization of A T-Helper Peptide from Carcinoembryonic Antigen

Ruiz, M., Kobayashi, H., Lasarte, J. J., Prieto, J., Borrás-Cuesta, F., Celis, E. & Sarobe, P., Apr 15 2004, In : Clinical Cancer Research. 10, 8, p. 2860-2867 8 p.

Research output: Contribution to journalArticle

11 Scopus citations

Multiepitope Trojan Antigen Peptide Vaccines for the Induction of Antitumor CTL and Th Immune Responses

Lu, J., Higashimoto, Y., Appella, E. & Celis, E., Apr 1 2004, In : Journal of Immunology. 172, 7, p. 4575-4582 8 p.

Research output: Contribution to journalArticle

66 Scopus citations

Recognition of adult T-cell leukemia/lymphoma cells by CD4+ helper T lymphocytes specific for human T-cell leukemia virus type I envelope protein

Kobayashi, H., Nagato, T., Yanai, M., Oikawa, K., Sato, K., Kimura, S., Tateno, M., Omiya, R. & Celis, E., Oct 15 2004, In : Clinical Cancer Research. 10, 20, p. 7053-7062 10 p.

Research output: Contribution to journalArticle

10 Scopus citations
2003

Identification of Naturally Processed Helper T-Cell Epitopes from Prostate-Specific Membrane Antigen Using Peptide-Based in Vitro Stimulation

Kobayashi, H., Omiya, R., Sodey, B., Yanai, M., Oikawa, K., Sato, K., Kimura, S., Senju, S., Nishimura, Y., Tateno, M. & Celis, E., Nov 1 2003, In : Clinical Cancer Research. 9, 14, p. 5386-5393 8 p.

Research output: Contribution to journalArticle

22 Scopus citations

Immune-mediated tumor regression induced by CpG-containing oligodeoxynucleotides

Baines, J. & Celis, E., Jul 1 2003, In : Clinical Cancer Research. 9, 7, p. 2693-2700 8 p.

Research output: Contribution to journalArticle

105 Scopus citations

Session III: Involvement of HLA-class II molecules in tumor rejection - The role of epitopes for tumor-reactive T cells

Celis, E., Kobayashi, H., Omiya, R., Sodey, B. & Appella, E., Dec 1 2003, In : Cancer Immunology, Immunotherapy. 52, SUPPL. 1

Research output: Contribution to journalArticle

Specificity and functional characteristics of anti-HLA-A mAbs LGIII-147.4. 1 and LGIII-220.6.2

Wang, X., Liang, B., Rebmann, V., Lu, J., Celis, E., Kageshita, T., Grosse-Wilde, H. & Ferrone, S., Aug 1 2003, In : Tissue Antigens. 62, 2, p. 139-148 10 p.

Research output: Contribution to journalArticle

17 Scopus citations
2002
938 Scopus citations