• 12163 Citations
  • 55 h-Index
1973 …2020

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Prominent role of secondary anchor residues in peptide binding to HLA-A2.1 molecules

Ruppert, J., Sidney, J., Celis, E., Kubo, R. T., Grey, H. M. & Sette, A., Sep 10 1993, In : Cell. 74, 5, p. 929-937 9 p.

Research output: Contribution to journalArticle

582 Scopus citations

Programmed death-ligand 1 and its soluble form are highly expressed in nasal natural killer/T-cell lymphoma: a potential rationale for immunotherapy

Nagato, T., Ohkuri, T., Ohara, K., Hirata, Y., Kishibe, K., Komabayashi, Y., Ueda, S., Takahara, M., Kumai, T., Ishibashi, K., Kosaka, A., Aoki, N., Oikawa, K., Uno, Y., Akiyama, N., Sado, M., Takei, H., Celis, E., Harabuchi, Y. & Kobayashi, H., Jul 1 2017, In : Cancer Immunology, Immunotherapy. 66, 7, p. 877-890 14 p.

Research output: Contribution to journalArticle

53 Scopus citations

Primary tumor-induced immunity eradicates disseminated tumor cells in syngeneic mouse model

Piranlioglu, R., Lee, E. M., Ouzounova, M., Bollag, R. J., Vinyard, A., Arbab, A. S., Marasco, D., Guzel, M., Cowell, J. K., Thangaraju, M., Chadli, A., Hassan, K. A., Wicha, M. S., Celis, E. & Korkaya, H., Dec 1 2019, In : Nature communications. 10, 1, 1430.

Research output: Contribution to journalArticle

6 Scopus citations

Presentation of an immunodominant T-cell epitope of hepatitis B surface antigen by the HLA-DPw4 molecule

Celis, E. & Karr, R. W., 1989, In : Journal of Virology. 63, 2, p. 747-752 6 p.

Research output: Contribution to journalArticle

Open Access
44 Scopus citations

PRDM1/Blimp-1 controls effector cytokine production in human NK cells

Smith, M. A., Maurin, M., Cho, H. I., Becknell, B., Freud, A. G., Yu, J., Wei, S., Djeu, J., Celis, E., Caligiuri, M. A. & Wright, K. L., Nov 15 2010, In : Journal of Immunology. 185, 10, p. 6058-6067 10 p.

Research output: Contribution to journalArticle

55 Scopus citations

Pools of lipidated HTL-CTL constructs prime for multiple HBV and HCV CTL epitope responses

Oseroff, C., Sette, A., Wentworth, P., Celis, E., Maewal, A., Dahlberg, C., Fikes, J., Kubo, R. T., Chesnut, R. W., Grey, H. M. & Alexander, J., May 1 1998, In : Vaccine. 16, 8, p. 823-833 11 p.

Research output: Contribution to journalArticle

36 Scopus citations

PKCθ is required for alloreactivity and GVHD but not for immune responses toward leukemia and infection in mice

Valenzuela, J. O., Iclozan, C., Hossain, M. S., Prlic, M., Hopewell, E., Bronk, C. C., Wang, J., Celis, E., Engelman, R. W., Blazar, B. R., Bevan, M. J., Waller, E. K., Yu, X. Z. & Beg, A. A., Dec 1 2009, In : Journal of Clinical Investigation. 119, 12, p. 3774-3786 13 p.

Research output: Contribution to journalArticle

57 Scopus citations

Peptide vaccine given with a toll-like receptor agonist is effective for the treatment and prevention of spontaneous breast tumors

Nava-Parada, P., Forni, G., Knutson, K. L., Pease, L. R. & Celis, E., Feb 1 2007, In : Cancer Research. 67, 3, p. 1326-1334 9 p.

Research output: Contribution to journalArticle

93 Scopus citations

Peptide vaccination of patients with metastatic melanoma: Improved clinical outcome in patients demonstrating effective immunization

Markovic, S. N., Suman, V. J., Ingle, J. N., Kaur, J. S., Pitot, H. C., Loprinzi, C. L., Rao, R. D., Creagan, E. T., Pittelkow, M. R., Allred, J. B., Nevala, W. K. & Celis, E., Aug 1 2006, In : American Journal of Clinical Oncology: Cancer Clinical Trials. 29, 4, p. 352-360 9 p.

Research output: Contribution to journalArticle

48 Scopus citations
12 Scopus citations

PD-L1-specific helper T-cells exhibit effective antitumor responses: New strategy of cancer immunotherapy targeting PD-L1 in head and neck squamous cell carcinoma

Hirata-Nozaki, Y., Ohkuri, T., Ohara, K., Kumai, T., Nagata, M., Harabuchi, S., Kosaka, A., Nagato, T., Ishibashi, K., Oikawa, K., Aoki, N., Ohara, M., Harabuchi, Y., Uno, Y., Takei, H., Celis, E. & Kobayashi, H., Jun 20 2019, In : Journal of Translational Medicine. 17, 1, 207.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Patients with chronic hepatitis C have circulating cytotoxic T cells which recognize hepatitis C virus-encoded peptides binding to HLA-A2.1 molecules

Battegay, M., Fikes, J., Di Bisceglie, A. M., Wentworth, P. A., Sette, A., Celis, E., Ching, W. M., Grakoui, A., Rice, C. M., Kurokohchi, K., Berzofsky, J. A., Hoofnagle, J. H., Feinstone, S. M. & Akatsuka, T., Apr 1995, In : Journal of Virology. 69, 4, p. 2462-2470 9 p.

Research output: Contribution to journalArticle

Open Access
205 Scopus citations

Oxidized lipids block antigen cross-presentation by dendritic cells in cancer

Cao, W., Ramakrishnan, R., Tuyrin, V. A., Veglia, F., Condamine, T., Amoscato, A., Mohammadyani, D., Johnson, J. J., Zhang, L. M., Klein-Seetharaman, J., Celis, E., Kagan, V. E. & Gabrilovich, D. I., Mar 15 2014, In : Journal of Immunology. 192, 6, p. 2920-2931 12 p.

Research output: Contribution to journalArticle

69 Scopus citations

Overlapping human leukocyte antigen class I/II binding peptide vaccine for the treatment of patients with stage IV melanoma: Evidence of systemic immune dysfunction

Celis, E., Markovic, S. N., Suman, V. J., Rao, R. D., Creagan, E. T., Knutson, K. L., Leontovich, A. A., Ingle, J. N., Kaur, J. S., Erickson, L. A., Pitot, H. C., Allred, J. B., Kottschade, L. A., McWilliams, R. R., Croghan, G. A. & Nevala, W. K., Jul 1 2007, In : Cancer. 110, 1, p. 203-214 12 p.

Research output: Contribution to journalArticle

32 Scopus citations

Oral administration of PPC enhances antigen-specific CD8+ T cell responses while reducing IgE levels in sensitized mice

Burrows, M., Assundani, D., Celis, E., Tufaro, F., Tanaka, A. & Bradley, W. G., Nov 30 2009, In : BMC Complementary and Alternative Medicine. 9, 49.

Research output: Contribution to journalArticle

7 Scopus citations

Optimized peptide vaccines eliciting extensive CD8 T-cell responses with therapeutic antitumor effects

Cho, H. I. & Celis, E., Dec 1 2009, In : Cancer Research. 69, 23, p. 9012-9019 8 p.

Research output: Contribution to journalArticle

88 Scopus citations

Optimized DNA vaccines to specifically induce therapeutic CD8 T cell responses against autochthonous breast tumors

Cho, H. I., Niu, G., Bradley, N. & Celis, E., Nov 2008, In : Cancer Immunology, Immunotherapy. 57, 11, p. 1695-1703 9 p.

Research output: Contribution to journalArticle

14 Scopus citations

Optimized combination therapy using bortezomib, TRAIL and TLR agonists in established breast tumors

Lee, S., Yagita, H., Sayers, T. J. & Celis, E., Jul 2010, In : Cancer Immunology, Immunotherapy. 59, 7, p. 1073-1081 9 p.

Research output: Contribution to journalArticle

12 Scopus citations

Optimization of peptide vaccines to induce robust antitumor CD4 T-cell responses

Kumai, T., Lee, S., Cho, H. I., Sultan, H., Kobayashi, H., Harabuchi, Y. & Celis, E., Jan 2017, In : Cancer Immunology Research. 5, 1, p. 72-83 12 p.

Research output: Contribution to journalArticle

24 Scopus citations

Nuclear and cytoplasmic cross-resistance and correlated sensitivity to DNA intercalating drugs in a petite-negative yeast

Celis, E., Mas, J. & Brunner, A., Feb 1975, In : Genetical Research. 25, 1, p. 59-69 11 p.

Research output: Contribution to journalArticle

8 Scopus citations

Novel toll-like receptor 2 ligands for targeted pancreatic cancer imaging and immunotherapy

Huynh, A. S., Chung, W. J., Cho, H. I., Moberg, V. E., Celis, E., Morse, D. L. & Vagner, J., Nov 26 2012, In : Journal of Medicinal Chemistry. 55, 22, p. 9751-9762 12 p.

Research output: Contribution to journalArticle

21 Scopus citations

NF-κB is crucial in proximal T-cell signaling for calcium influx and NFAT activation

Bronk, C. C., Yoder, S., Hopewell, E. L., Yang, S., Celis, E., Yu, X. Z. & Beg, A. A., 2014, In : European Journal of Immunology. 44, 12, p. 3741-3746 6 p.

Research output: Contribution to journalArticle

7 Scopus citations

Mutated BRAF emerges as a major effector of recurrence in a murine melanoma model after treatment with immunomodulatory agents

Zaidi, S., Blanchard, M., Shim, K., Ilett, E., Rajani, K., Parrish, C., Boisgerault, N., Kottke, T., Thompson, J., Celis, E., Pulido, J., Selby, P., Pandha, H., Melcher, A., Harrington, K. & Vile, R., May 9 2015, In : Molecular Therapy. 23, 5, p. 845-856 12 p.

Research output: Contribution to journalArticle

8 Scopus citations

Multiepitope Trojan Antigen Peptide Vaccines for the Induction of Antitumor CTL and Th Immune Responses

Lu, J., Higashimoto, Y., Appella, E. & Celis, E., Apr 1 2004, In : Journal of Immunology. 172, 7, p. 4575-4582 8 p.

Research output: Contribution to journalArticle

66 Scopus citations

Modulation of the immunological response to hepatitis b virus by antibodies

Celis, E., Abraham, K. G. & Miller, R. W., Jan 1 1987, In : Hepatology. 7, 3, p. 563-568 6 p.

Research output: Contribution to journalArticle

43 Scopus citations

MHC-binding peptides as immunotherapeutics for cancer

Kobayashi, H., Kennedy, R., Lu, J., Davila, E. & Celis, E., Jan 1 2000, In : Immunological Investigations. 29, 2, p. 105-110 6 p.

Research output: Contribution to journalArticle

7 Scopus citations

Mechanism of T cell tolerance induced by myeloid-derived suppressor cells

Nagaraj, S., Schrum, A. G., Cho, H. I., Celis, E. & Gabrilovich, D. I., Mar 15 2010, In : Journal of Immunology. 184, 6, p. 3106-3116 11 p.

Research output: Contribution to journalArticle

241 Scopus citations

Lung tumor NF-κB signaling promotes T cell-mediated immune surveillance

Hopewell, E. L., Zhao, W., Fulp, W. J., Bronk, C. C., Lopez, A. S., Massengill, M., Antonia, S., Celis, E., Haura, E. B., Enkemann, S. A., Chen, D. T. & Beg, A. A., Jun 3 2013, In : Journal of Clinical Investigation. 123, 6, p. 2509-2522 14 p.

Research output: Contribution to journalArticle

53 Scopus citations

Localization and immunological characterization of antigenic domains of the rabies virus internal N and NS proteins

Dietzschold, B., Lafon, M., Wang, H., Otvos, L., Celis, E., Wunner, W. H. & Koprowski, H., Aug 1987, In : Virus Research. 8, 2, p. 103-125 23 p.

Research output: Contribution to journalArticle

80 Scopus citations

Local activation of p53 in the tumor microenvironment overcomes immune suppression and enhances antitumor immunity

Guo, G., Yu, M., Xiao, W., Celis, E. & Cui, Y., May 1 2017, In : Cancer Research. 77, 9, p. 2292-2305 14 p.

Research output: Contribution to journalArticle

35 Scopus citations

Lipid bodies containing oxidatively truncated lipids block antigen cross-presentation by dendritic cells in cancer

Veglia, F., Tyurin, V. A., Mohammadyani, D., Blasi, M., Duperret, E. K., Donthireddy, L., Hashimoto, A., Kapralov, A., Amoscato, A., Angelini, R., Patel, S., Alicea-Torres, K., Weiner, D., Murphy, M. E., Klein-Seetharaman, J., Celis, E., Kagan, V. E. & Gabrilovich, D. I., Dec 1 2017, In : Nature communications. 8, 1, 2122.

Research output: Contribution to journalArticle

36 Scopus citations

Lipid accumulation and dendritic cell dysfunction in cancer

Herber, D. L., Cao, W., Nefedova, Y., Novitskiy, S. V., Nagaraj, S., Tyurin, V. A., Corzo, A., Cho, H. I., Celis, E., Lennox, B., Knight, S. C., Padhya, T., McCaffrey, T. V., McCaffrey, J. C., Antonia, S., Fishman, M., Ferris, R. L., Kagan, V. E. & Gabrilovich, D. I., Aug 2010, In : Nature Medicine. 16, 8, p. 880-886 7 p.

Research output: Contribution to journalArticle

259 Scopus citations

Lack of effective T-lymphocyte response to the PAX3/FKHR translocation area in alveolar rhabdomyosarcoma

Rodeberg, D. A., Nuss, R. A., Heppelmann, C. J. & Celis, E., Jun 2005, In : Cancer Immunology, Immunotherapy. 54, 6, p. 526-534 9 p.

Research output: Contribution to journalArticle

16 Scopus citations

Isolation and characterization of human T cell lines and clones reactive to rabies virus: Antigen specificity and production of interferon-γ

Celis, E., Miller, R. W., Wiktor, T. J., Dietzschold, B. & Koprowski, H., Apr 3 1986, In : Journal of Immunology. 136, 2, p. 692-697 6 p.

Research output: Contribution to journalArticle

41 Scopus citations
1 Scopus citations

In vivo expansion, persistence, and function of peptide vaccine-induced CD8 T cells occur independently of CD4 T cells

Assudani, D., Cho, H. I., DeVito, N., Bradley, N. & Celis, E., Dec 1 2008, In : Cancer Research. 68, 23, p. 9892-9899 8 p.

Research output: Contribution to journalArticle

45 Scopus citations

In Vitro Response to HBsAg of Peripheral Blood Lymphocytes from Recipients of Hepatitis B Vaccine

Chang, T. W., Celis, E., Miller, R. W., Zurawski, V. R. & Kung, P. C., Jan 1 1984, In : Hepatology. 4, 5, p. 824-829 6 p.

Research output: Contribution to journalArticle

17 Scopus citations

In vitro peptide immunization of target tax protein human T-cell leukemia virus type 1-specific CD4+ helper T lymphocytes

Kobayashi, H., Ngato, T., Sato, K., Aoki, N., Kimura, S., Tanaka, Y., Aizawa, H., Tateno, M. & Celis, E., Jun 15 2006, In : Clinical Cancer Research. 12, 12, p. 3814-3822 9 p.

Research output: Contribution to journalArticle

10 Scopus citations

In vitro induction of primary, antigen-specific CTL from human peripheral blood mononuclear cells stimulated with synthetic peptides

Wentworth, P. A., Celis, E., Crimi, C., Stitely, S., Hale, L., Tsai, V., Serra, H. M., Guercio, M. F. D., Livingston, B., Alazard, D., Fikes, J., Kubo, R. T., Grey, H. M., Chesnut, R. W., Chisari, F. V. & Sette, A., Jan 1 1995, In : Molecular Immunology. 32, 9, p. 603-612 10 p.

Research output: Contribution to journalArticle

48 Scopus citations

In vitro induction of immune responses to shared tumor-associated antigens in rhabdomyosarcoma

Rodeberg, D. A., Erskine, C. & Celis, E., Aug 1 2007, In : Journal of Pediatric Surgery. 42, 8, p. 1396-1402 7 p.

Research output: Contribution to journalArticle

9 Scopus citations

In vitro immunization and expansion of antigen-specific cytotoxic T lymphocytes for adoptive immunotherapy using peptide-pulsed dendritic cells

Tsai, V., Kawashima, I., Keogh, E., Daly, K., Sette, A. & Celis, E., Jan 1 1997, In : Critical Reviews in Immunology. 18, 1-2, p. 65-75 11 p.

Research output: Contribution to journalArticle

60 Scopus citations

Intratumoral electroporation of IL-12 cDNA eradicates established melanomas by Trp2180-188-specific CD8+ CTLs in a perforin/granzyme-mediated and IFN-c-dependent manner: Application of Trp2180-188 peptides

Sin, J. I., Park, J. B., Lee, I. H., Park, D., Choi, Y. S., Choe, J. & Celis, E., Oct 2012, In : Cancer Immunology, Immunotherapy. 61, 10, p. 1671-1682 12 p.

Research output: Contribution to journalArticle

27 Scopus citations

Intratumoral administration of cGAMP transiently accumulates potent macrophages for anti-tumor immunity at a mouse tumor site

Ohkuri, T., Kosaka, A., Ishibashi, K., Kumai, T., Hirata, Y., Ohara, K., Nagato, T., Oikawa, K., Aoki, N., Harabuchi, Y., Celis, E. & Kobayashi, H., Jun 1 2017, In : Cancer Immunology, Immunotherapy. 66, 6, p. 705-716 12 p.

Research output: Contribution to journalArticle

32 Scopus citations

Interleukin 15 promotes antigen-independent in vitro expansion and long-term survival of antitumor cytotoxic T lymphocytes

Lu, J., Giuntoli, R. L., Omiya, R., Kobayashi, H., Kennedy, R. & Celis, E., Dec 1 2002, In : Clinical Cancer Research. 8, 12, p. 3877-3884 8 p.

Research output: Contribution to journalArticle

50 Scopus citations

Interferon γ limits the effectiveness of melanoma peptide vaccines

Cho, H. I., Lee, Y. R. & Celis, E., Jan 6 2011, In : Blood. 117, 1, p. 135-144 10 p.

Research output: Contribution to journalArticle

42 Scopus citations

Interactions between a novel cell surface glycoprotein and the H‐2K and H‐2D antigens on myeloma tumor cells

Celis, E. & Eisen, H. N., Jun 1980, In : European Journal of Immunology. 10, 6, p. 455-461 7 p.

Research output: Contribution to journalArticle

5 Scopus citations

Inhibition of EBV-induced lymphoproliferation by CD4+ T cells specific for an MHC class II promiscuous epitope

Omiya, R., Buteau, C., Kobayashi, H., Paya, C. V. & Celis, E., Aug 15 2002, In : Journal of Immunology. 169, 4, p. 2172-2179 8 p.

Research output: Contribution to journalArticle

65 Scopus citations

Induction of tumor-reactive T helper responses by a posttranslational modified epitope from tumor protein p53

Kumai, T., Ishibashi, K., Oikawa, K., Matsuda, Y., Aoki, N., Kimura, S., Hayashi, S., Kitada, M., Harabuchi, Y., Celis, E. & Kobayashi, H., May 2014, In : Cancer Immunology, Immunotherapy. 63, 5, p. 469-478 10 p.

Research output: Contribution to journalArticle

15 Scopus citations

Induction of protective immunity against rabies by immunization with rabies virus ribonucleoprotein.

Dietzschold, B., Wang, H. H., Rupprecht, C. E., Celis, E., Tollis, M., Ertl, H., Heber-Katz, E. & Koprowski, H., Dec 1987, In : Proceedings of the National Academy of Sciences of the United States of America. 84, 24, p. 9165-9169 5 p.

Research output: Contribution to journalArticle

134 Scopus citations

InducTION of mage-A3 and HPV-16 immunity by Trojan vaccines in patients with head and neck carcinoma

Voskens, C. J., Sewell, D., Hertzano, R., Desanto, J., Rollins, S., Lee, M., Taylor, R., Wolf, J., Suntharalingam, M., Gastman, B., Papadimitriou, J. C., Lu, C., Tan, M., Morales, R., Cullen, K., Celis, E., Mann, D. & Strome, S. E., Dec 2012, In : Head and Neck. 34, 12, p. 1734-1746 13 p.

Research output: Contribution to journalArticle

35 Scopus citations