• 12253 Citations
  • 56 h-Index
1973 …2020

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InducTION of mage-A3 and HPV-16 immunity by Trojan vaccines in patients with head and neck carcinoma

Voskens, C. J., Sewell, D., Hertzano, R., Desanto, J., Rollins, S., Lee, M., Taylor, R., Wolf, J., Suntharalingam, M., Gastman, B., Papadimitriou, J. C., Lu, C., Tan, M., Morales, R., Cullen, K., Celis, E., Mann, D. & Strome, S. E., Dec 2012, In : Head and Neck. 34, 12, p. 1734-1746 13 p.

Research output: Contribution to journalArticle

35 Scopus citations

Induction of EBV-latent membrane protein 1-specific MHC class II-restricted T-cell responses against natural killer lymphoma cells

Kobayashi, H., Nagato, T., Takahara, M., Sato, K., Kimura, S., Aoki, N., Azumi, M., Tateno, M., Harabuchi, Y. & Celis, E., Feb 1 2008, In : Cancer Research. 68, 3, p. 901-908 8 p.

Research output: Contribution to journalArticle

33 Scopus citations

Induction of antitumor cytotoxic T lymphocytes with a MAGE-3-encoded synthetic peptide presented by human leukocytes antigen-A24

Tanaka, F., Fujie, T., Tahara, K., Mori, M., Takesako, K., Sette, A., Celis, E. & Akiyoshi, T., Oct 15 1997, In : Cancer Research. 57, 20, p. 4465-4468 4 p.

Research output: Contribution to journalArticle

97 Scopus citations

Induction of anti-tumor cytotoxic T lymphocytes in normal humans using primary cultures and synthetic peptide epitopes

Celis, E., Tsai, V., Crimi, C., Demars, R., Wentworth, P. A., Chesnut, R. W., Grey, H. M., Sette, A. & Serra, H. M., Mar 15 1994, In : Proceedings of the National Academy of Sciences of the United States of America. 91, 6, p. 2105-2109 5 p.

Research output: Contribution to journalArticle

295 Scopus citations

Immune-mediated tumor regression induced by CpG-containing oligodeoxynucleotides

Baines, J. & Celis, E., Jul 1 2003, In : Clinical Cancer Research. 9, 7, p. 2693-2700 8 p.

Research output: Contribution to journalArticle

105 Scopus citations

Immature myeloid cells directly contribute to skin tumor development by recruiting IL-17-producing CD4+ T cells

Ortiz, M. L., Kumar, V., Martner, A., Mony, S., Donthireddy, L., Condamine, T., Seykora, J., Knight, S. C., Malietzis, G., Lee, G. H., Moorghen, M., Lenox, B., Luetteke, N., Celis, E. & Gabrilovich, D., Mar 9 2015, In : Journal of Experimental Medicine. 212, 3, p. 351-367 17 p.

Research output: Contribution to journalArticle

37 Scopus citations

Identification of α-fetoprotein-specific T-cell receptors for hepatocellular carcinoma immunotherapy

Zhu, W., Peng, Y., Wang, L., Hong, Y., Jiang, X., Li, Q., Liu, H., Huang, L., Wu, J., Celis, E., Merchen, T. D., Kruse, E. J. & He, Y., Aug 2018, In : Hepatology. 68, 2, p. 574-589 16 p.

Research output: Contribution to journalArticle

15 Scopus citations

Identification of Subdominant CTL Epitopes of the GP100 Melanoma-Associated Tumor Antigen by Primary in Vitro Immunization with Peptide-Pulsed Dendritic Cells

Tsai, V., Southwood, S., Sidney, J., Sakaguchi, K., Kawakami, Y., Appella, E., Sette, A. & Celis, E., Feb 15 1997, In : Journal of Immunology. 158, 4, p. 1796-1802 7 p.

Research output: Contribution to journalArticle

165 Scopus citations

Identification of potential CTL epitopes of tumor-associated antigen MAGE-1 for five common HLA-A alleles

Celis, E., Fikes, J., Wentworth, P., Sidney, J., Southwood, S., Maewal, A., Del Guercio, M. F., Sette, A. & Livingston, B., Dec 1994, In : Molecular Immunology. 31, 18, p. 1423-1430 8 p.

Research output: Contribution to journalArticle

60 Scopus citations

Identification of new HER2/neu-derived peptide epitopes that can elicit specific CTL against autologous and allogeneic carcinomas and melanomas

Rongcun, Y., Salazar-Onfray, F., Charo, J., Malmberg, K. J., Evrin, K., Maes, H., Kono, K., Hising, C., Petersson, M., Larsson, O., Lan, L., Appella, E., Sette, A., Celis, E. & Kiessling, R., Jul 15 1999, In : Journal of Immunology. 163, 2, p. 1037-1044 8 p.

Research output: Contribution to journalArticle

164 Scopus citations

Identification of new epitopes from four different tumor-associated antigens: Recognition of naturally processed epitopes correlates with HLA-A*0201-binding affinity

Keogh, E., Fikes, J., Southwood, S., Celis, E., Chesnut, R. & Sette, A., Jul 15 2001, In : Journal of Immunology. 167, 2, p. 787-796 10 p.

Research output: Contribution to journalArticle

118 Scopus citations

Identification of Naturally Processed Helper T-Cell Epitopes from Prostate-Specific Membrane Antigen Using Peptide-Based in Vitro Stimulation

Kobayashi, H., Omiya, R., Sodey, B., Yanai, M., Oikawa, K., Sato, K., Kimura, S., Senju, S., Nishimura, Y., Tateno, M. & Celis, E., Nov 1 2003, In : Clinical Cancer Research. 9, 14, p. 5386-5393 8 p.

Research output: Contribution to journalArticle

22 Scopus citations

Identification of HLA-A3-restricted cytotoxic T lymphocyte epitopes from carcinoembryonic antigen and HER-2/neu by primary in vitro immunization with peptide-pulsed dendritic cells

Kawashima, I., Tsai, V., Southwood, S., Takesako, K., Sette, A. & Celis, E., Jan 16 1999, In : Cancer Research. 59, 2, p. 431-435 5 p.

Research output: Contribution to journalArticle

121 Scopus citations

Identification of HLA-A24 epitope peptides of carcinoembryonic antigen which induce tumor-reactive cytotoxic T lymphocyte

Nukaya, I., Yasumoto, M., Iwasaki, T., Ideno, M., Sette, A., Celis, E., Takesako, K. & Kato, I., Jan 5 1999, In : International Journal of Cancer. 80, 1, p. 92-97 6 p.

Research output: Contribution to journalArticle

103 Scopus citations

Identification of HLA-A*03, A*11 and B*07-restricted melanoma-associated peptides that are immunogenic in vivo by vaccine-induced immune response (VIIR) analysis

Reynolds, S. R., Celis, E., Sette, A., Oratz, R., Shapiro, R. L., Johnston, D., Fotino, M. & Bystryn, J. C., Oct 20 2000, In : Journal of Immunological Methods. 244, 1-2, p. 59-67 9 p.

Research output: Contribution to journalArticle

21 Scopus citations

Identification of HER2/neu-derived peptide epitopes recognized by gastric cancer-specific cytotoxic T lymphocytes

Kono, K., Rongcun, Y., Charo, J., Ichihara, F., Celis, E., Sette, A., Appella, E., Sekikawa, T., Matsumoto, Y. & Kiessung, R., 1998, In : International Journal of Cancer. 78, 2, p. 202-208 7 p.

Research output: Contribution to journalArticle

77 Scopus citations

Identification of helper T-cell epitopes that encompass or lie proximal to cytotoxic T-cell epitopes in the gp100 melanoma tumor antigen

Kobayashi, H., Lu, J. & Celis, E., Oct 15 2001, In : Cancer Research. 61, 20, p. 7577-7584 8 p.

Research output: Contribution to journalArticle

66 Scopus citations

Identification of GP100-derived, melanoma-specific cytotoxic T- lymphocyte epitopes restricted by HLA-A3 supertype molecules by primary in vitro immunization with peptide-pulsed dendritic cells

Kawashtma, I., Tsai, V., Southwood, S., Takesako, K., Celis, E. & Sette, A., Nov 2 1998, In : International Journal of Cancer. 78, 4, p. 518-524 7 p.

Research output: Contribution to journalArticle

39 Scopus citations
19 Scopus citations

Identification of an antigenic epitope for helper T lymphocytes from carcinoembryonic antigen

Kobayashi, H., Omiya, R., Ruiz, M., Huarte, E., Sarobe, P., Lasarte, J. J., Herraiz, M., Sangro, B., Prieto, J., Borras-Cuesta, F. & Celis, E., Oct 1 2002, In : Clinical Cancer Research. 8, 10, p. 3219-3225 7 p.

Research output: Contribution to journalArticle

49 Scopus citations

Identification of a MAGE-2-encoded human leukocyte antigen-A24-binding synthetic peptide that induces specific antitumor cytotoxic T lymphocytes

Tahara, K., Takesako, K., Sette, A., Celis, E., Kitano, S. & Akiyoshi, T., Aug 1 1999, In : Clinical Cancer Research. 5, 8, p. 2236-2241 6 p.

Research output: Contribution to journalArticle

33 Scopus citations

Identification of A2-restricted hepatitis C virus-specific cytotoxic T lymphocyte epitopes from conserved regions of the viral genome

Wentworth, P. A., Sette, A., Celis, E., Sidney, J., Southwood, S., Crimi, C., Stitely, S., Keogh, E., Wong, N. C., Livingston, B., Alazard, D., Vitiello, A., Grey, H. M., Chisari, F. V., Chesnut, R. W. & Fikes, J., Jan 1 1996, In : International Immunology. 8, 5, p. 651-659 9 p.

Research output: Contribution to journalArticle

65 Scopus citations

Identification and Characterization of A T-Helper Peptide from Carcinoembryonic Antigen

Ruiz, M., Kobayashi, H., Lasarte, J. J., Prieto, J., Borrás-Cuesta, F., Celis, E. & Sarobe, P., Apr 15 2004, In : Clinical Cancer Research. 10, 8, p. 2860-2867 8 p.

Research output: Contribution to journalArticle

11 Scopus citations

HLA-independent heterogeneity of CD8+ T cell responses to MAGE-3, Melan-A/MART-1, gp100, tyrosinase, MC1R, and TRP-2 in vaccine-treated melanoma patients

Reynolds, S. R., Celis, E., Sette, A., Oratz, R., Shapiro, R. L., Johnston, D., Fotino, M. & Bystryn, J. C., Dec 15 1998, In : Journal of Immunology. 161, 12, p. 6970-6976 7 p.

Research output: Contribution to journalArticle

74 Scopus citations

HIF-1α regulates function and differentiation of myeloid-derived suppressor cells in the tumor microenvironment

Corzo, C. A., Condamine, T., Lu, L., Cotter, M. J., Youn, J. I., Cheng, P., Cho, H. I., Celis, E., Quiceno, D. G., Padhya, T., McCaffrey, T. V., McCaffrey, J. C. & Gabrilovich, D. I., Oct 25 2010, In : Journal of Experimental Medicine. 207, 11, p. 2439-2453 15 p.

Research output: Contribution to journalArticle

589 Scopus citations

Hepatitis B virus-reactive human T-lymphocyte clones: Antigen specificity and helper function or antibody synthesis

Celis, E., Kung, P. C. & Chang, T. W., Jan 1 1984, In : Journal of Immunology. 132, 3, p. 1511-1516 6 p.

Research output: Contribution to journalArticle

48 Scopus citations

HBsAg‐Serum Protein Complexes Stimulate Immune T Lymphocytes More Efficiently Than Do Pure HBsAg

Celis, E. & Chang, T. W., Jan 1 1984, In : Hepatology. 4, 6, p. 1116-1123 8 p.

Research output: Contribution to journalArticle

19 Scopus citations

H3K4me3 mediates the NF-κB p50 homodimer binding to the pdcd1 promoter to activate PD-1 transcription in T cells

Redd, P. S., Lu, C., Klement, J. D., Ibrahim, M. L., Zhou, G., Kumai, T., Celis, E. & Liu, K., Sep 2 2018, In : OncoImmunology. 7, 9, e1483302.

Research output: Contribution to journalArticle

6 Scopus citations

Genetic restriction and fine specificity of human T cell clones reactive with rabies virus

Celis, E., Karr, R. W., Dietzschold, B., Wunner, W. H. & Koprowski, H., 1988, In : Journal of Immunology. 141, 8, p. 2721-2728 8 p.

Research output: Contribution to journalArticle

34 Scopus citations

Generation of tumor-specific cytolytic T lymphocytes from peripheral blood of cervical cancer patients by in vitro stimulation with a synthetic human papillomavirus type 16 E7 epitope

Alexander, M., Salgaller, M. L., Celis, E., Sette, A., Barnes, W. A., Rosenberg, S. A. & Steller, M. A., 1996, In : American journal of obstetrics and gynecology. 175, 6, p. 1586-1593 8 p.

Research output: Contribution to journalArticle

88 Scopus citations

Generation of tumoricidal PAX3 peptide antigen specific cytotoxic T lymphocytes

Rodeberg, D. A., Nuss, R. A., Elsawa, S. F., Erskine, C. L. & Celis, E., Jul 1 2006, In : International Journal of Cancer. 119, 1, p. 126-132 7 p.

Research output: Contribution to journalArticle

7 Scopus citations

Functional analysis of MHC Class II- restricted T cells derived from a Caucasian with a DR4, Dw15, DQw8 Haplotype

Celis, E., Karr, R. W., Gregersen, P. K. & Reinsmoen, N. L., Sep 1990, In : Human Immunology. 29, 1, p. 31-41 11 p.

Research output: Contribution to journalArticle

7 Scopus citations

Functional analysis of birch pollen allergen Bet v 1-specific regulatory T cells

Nagato, T., Kobayashi, H., Yanai, M., Sato, K., Aoki, N., Oikawa, K., Kimura, S., Abe, Y., Celis, E., Harabuchi, Y. & Tateno, M., Jan 15 2007, In : Journal of Immunology. 178, 2, p. 1189-1198 10 p.

Research output: Contribution to journalArticle

18 Scopus citations

Focal adhesion kinase as an immunotherapeutic target

Kobayashi, H., Azumi, M., Kimura, Y., Sato, K., Aoki, N., Kimura, S., Honma, M., Iizuka, H., Tateno, M. & Celis, E., Jun 2009, In : Cancer Immunology, Immunotherapy. 58, 6, p. 931-940 10 p.

Research output: Contribution to journalArticle

3 Scopus citations
9 Scopus citations

Expression, specificity and immunotherapy potential of prostate-associated genes in murine cell lines

Grossmann, M. E., Wood, M. & Celis, E., 2001, In : World Journal of Urology. 19, 5, p. 365-370 6 p.

Research output: Contribution to journalArticle

20 Scopus citations

Existence of MHC class I-restricted alloreactive CD4+ T cells reacting with peptide transporter-deficient cells

Kobayashi, H., Kimura, S., Aoki, N., Sato, K., Celis, E. & Katagiri, M., Jan 1 2001, In : Immunogenetics. 53, 8, p. 626-633 8 p.

Research output: Contribution to journalArticle

9 Scopus citations

Ethidium bromide uptake and change of fluorescence by petite-negative yeast mutants resistant to this drug

Celis, E., Mas, J. & Brunner, A., Oct 1 1975, In : FEBS Letters. 57, 3, p. 241-244 4 p.

Research output: Contribution to journalArticle

2 Scopus citations

ER stress regulates myeloid-derived suppressor cell fate through TRAIL-R-mediated apoptosis

Condamine, T., Kumar, V., Ramachandran, I. R., Youn, J. I., Celis, E., Finnberg, N., El-Deiry, W. S., Winograd, R., Vonderheide, R. H., English, N. R., Knight, S. C., Yagita, H., McCaffrey, J. C., Antonia, S., Hockstein, N., Witt, R., Masters, G., Bauer, T. & Gabrilovich, D. I., Jun 2 2014, In : Journal of Clinical Investigation. 124, 6, p. 2626-2639 14 p.

Research output: Contribution to journalArticle

140 Scopus citations

Epitope selection and development of peptide based vaccines to treat cancer

Celis, E., Sette, A. & Grey, H. M., Jan 1 1995, In : Seminars in Cancer Biology. 6, 6, p. 329-336 8 p.

Research output: Contribution to journalArticle

48 Scopus citations

Epigenetic modification augments the immunogenicity of human leukocyte antigen G serving as a tumor antigen for T cell-based immunotherapy

Ishibashi, K., Kumai, T., Ohkuri, T., Kosaka, A., Nagato, T., Hirata, Y., Ohara, K., Oikawa, K., Aoki, N., Akiyama, N., Sado, M., Kitada, M., Harabuchi, Y., Celis, E. & Kobayashi, H., Jun 2 2016, In : OncoImmunology. 5, 6, e1169356.

Research output: Contribution to journalArticle

10 Scopus citations

Enhancing immunogenicity of a CTL epitope from carcinoembryonic antigen by selective amino acid replacements

Huarte, E., Sarobe, P., Lu, J., Casares, N., Lasarte, J. J., Dotor, J., Ruiz, M., Prieto, J., Celis, E. & Borrás-Cuesta, F., 2002, In : Clinical Cancer Research. 8, 7, p. 2336-2344 9 p.

Research output: Contribution to journalArticle

26 Scopus citations

Enhanced therapeutic efficacy and memory of tumor-specific CD8 T cells by ex vivo PI3K-δ inhibition

Abu Eid, R., Ahmad, S., Lin, Y., Webb, M., Berrong, Z., Shrimali, R. K., Kumai, T., Ananth, S., Rodriguez, P. C., Celis, E., Janik, J. E., Mkrtichyan, M. & Khleif, S. N., Aug 1 2017, In : Cancer Research. 77, 15, p. 4135-4145 11 p.

Research output: Contribution to journalArticle

23 Scopus citations

EGFR inhibitors augment antitumour helper T-cell responses of HER family-specific immunotherapy

Kumai, T., Matsuda, Y., Oikawa, K., Aoki, N., Kimura, S., Harabuchi, Y., Celis, E. & Kobayashi, H., Oct 15 2013, In : British Journal of Cancer. 109, 8, p. 2155-2166 12 p.

Research output: Contribution to journalArticle

34 Scopus citations
7 Scopus citations

Effect of O2, ergosterol and sterol precursors on the mating ability of Kluyveromyces lactis

Mas, J., Celis, E., Piña, E. & Brunner, A., Nov 27 1974, In : Biochemical and Biophysical Research Communications. 61, 2, p. 613-620 8 p.

Research output: Contribution to journalArticle

2 Scopus citations

Effective antitumor peptide vaccines can induce severe autoimmune pathology

Sultan, H., Trillo-Tinoco, J., Rodriguez, P. & Celis, E., 2017, In : Oncotarget. 8, 41, p. 70317-70331 15 p.

Research output: Contribution to journalArticle

6 Scopus citations

Direct cross-priming by Th lymphocytes generates memory cytotoxic T cell responses

Kennedy, R., Undale, A. H., Kieper, W. C., Block, M. S., Pease, L. R. & Celis, E., Apr 1 2005, In : Journal of Immunology. 174, 7, p. 3967-3977 11 p.

Research output: Contribution to journalArticle

25 Scopus citations

Direct costimulation of tumor-reactive CTL by helper T cells potentiate their proliferation, survival, and effector function

Giuntoli, R. L., Lu, J., Kobayashi, H., Kennedy, R. & Celis, E., 2002, In : Clinical Cancer Research. 8, 3, p. 922-931 10 p.

Research output: Contribution to journalArticle

74 Scopus citations

Detection of t helper responses, but not of human papillomavirus-specific cytotoxic t lymphocyte responses, after peptide vaccination of patients with cervical carcinoma

Ressing, M. E., van Driel, W. J., Brandt, R. M. P., Kenter, G. G., de Jong, J. H., Bauknecht, T., Fleuren, G. J., Hoogerhout, P., Offringa, R., Sette, A., Celis, E., Grey, H., Trimbos, B. J., Kast, W. M. & Melief, C. J. M., 2000, In : Journal of Immunotherapy. 23, 2, p. 255-266 12 p.

Research output: Contribution to journalArticle

151 Scopus citations