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Research Output 1973 2019

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120 Citations (Scopus)

Defining promiscuous MHC class II helper T-cell epitopes for the HER2/neu tumor antigen

Kobayashi, H., Wood, M., Song, Y., Appella, E. & Celis, E., Sep 15 2000, In : Cancer Research. 60, 18, p. 5228-5236 9 p.

Research output: Contribution to journalArticle

T-Lymphocyte Epitopes
Neoplasm Antigens
Helper-Inducer T-Lymphocytes
Peptides
Cancer Vaccines
35 Citations (Scopus)

Defining MHC class II T helper epitopes for WT1 tumor antigen

Kobayashi, H., Nagato, T., Aoki, N., Sato, K., Kimura, S., Tateno, M. & Celis, E., Jul 1 2006, In : Cancer Immunology, Immunotherapy. 55, 7, p. 850-860 11 p.

Research output: Contribution to journalArticle

Wilms' Tumor Genes
Wilms Tumor
Neoplasm Antigens
Helper-Inducer T-Lymphocytes
Epitopes
218 Citations (Scopus)

Defective processing and presentation of exogenous antigens in mutants with normal HLA class II genes

Mellins, E., Smith, L., Arp, B., Cotner, T., Celis, E. & Pious, D., Jan 1 1990, In : Nature. 343, 6253, p. 71-74 4 p.

Research output: Contribution to journalArticle

MHC Class II Genes
Antigen Presentation
Peptides
Major Histocompatibility Complex
Antigen-Presenting Cells
18 Citations (Scopus)

Cytoplasmic and nuclear inheritance of resistance to alkylguanidines and ethidium bromide in a petite-negative yeast

Brunner, A., Mas, J., Celis, E. & Mattoon, J. R., Jul 17 1973, In : Biochemical and Biophysical Research Communications. 53, 2, p. 638-644 7 p.

Research output: Contribution to journalArticle

Extrachromosomal Inheritance
Ethidium
Yeast
Yeasts
Oxidative Phosphorylation
9 Citations (Scopus)
Membrane Glycoproteins
T-Lymphocytes
Serum
Neoplasms
Cytotoxic T-Lymphocytes
4 Citations (Scopus)

Cyclical changes in susceptibility of a myeloma tumor (LPC-1) to immune destruction. II. Periodic fluctuations during growth in normal and nude mice and in culture

Hale, A. H., Celis, E., Russell, J. H. & Eisen, H. N., Dec 1 1979, In : Journal of Immunology. 122, 3, p. 959-964 6 p.

Research output: Contribution to journalArticle

Nude Mice
Cytotoxic T-Lymphocytes
Growth
Neoplasms
Phenotype
14 Citations (Scopus)

Cyclical changes in susceptibility of a myeloma tumor (LPC-1) to immune destruction. I. Changes in reactivity with cytotoxic T lymphocytes and anti-H-2(d) sera

Celis, E., Hale, A. H., Russell, J. H. & Eisen, H. N., Dec 1 1979, In : Journal of Immunology. 122, 3, p. 954-958 5 p.

Research output: Contribution to journalArticle

Cytotoxic T-Lymphocytes
Serum
Neoplasms
Minor Histocompatibility Antigens
Ascites
46 Citations (Scopus)

Creating space: An antigen-independent, CpG-induced peripheral expansion of naive and memory T lymphocytes in a full T-cell compartment

Davila, E., Velez, M. G., Heppelmann, C. J. & Celis, E., Oct 1 2002, In : Blood. 100, 7, p. 2537-2545 9 p.

Research output: Contribution to journalArticle

Computer peripheral equipment
T-cells
T-Lymphocytes
Antigens
Data storage equipment
32 Citations (Scopus)

Crawling movements of lymphocytes on and beneath fibroblasts in culture

Chang, T. W., Celis, E., Eisen, H. N. & Solomon, F., Jan 1 1979, In : Proceedings of the National Academy of Sciences of the United States of America. 76, 6, p. 2917-2921 5 p.

Research output: Contribution to journalArticle

Fibroblasts
Lymphocytes
T-Lymphocytes
T-Cell Leukemia
3T3 Cells
59 Citations (Scopus)

Consensus nomenclature for CD8+ T cell phenotypes in cancer

Apetoh, L., Smyth, M. J., Drake, C. G., Abastado, J. P., Apte, R. N., Ayyoub, M., Blay, J. Y., Bonneville, M., Butterfield, L. H., Caignard, A., Castelli, C., Cavallo, F., Celis, E., Chen, L., Colombo, M. P., Comin-Anduix, B., Coukos, G., Dhodapkar, M. V., Dranoff, G., Frazer, I. H. & 39 others, Fridman, W. H., Gabrilovich, D. I., Gilboa, E., Gnjatic, S., Jäger, D., Kalinski, P., Kaufman, H. L., Kiessling, R., Kirkwood, J., Knuth, A., Liblau, R., Lotze, M. T., Lugli, E., Marincola, F., Melero, I., Melief, C. J., Mempel, T. R., Mittendorf, E. A., Odun, K., Overwijk, W. W., Palucka, A. K., Parmiani, G., Ribas, A., Romero, P., Schreiber, R. D., Schuler, G., Srivastava, P. K., Tartour, E., Valmori, D., van der Burg, S. H., van der Bruggen, P., van den Eynde, B. J., Wang, E., Zou, W., Whiteside, T. L., Speiser, D. E., Pardoll, D. M., Restifo, N. P. & Anderson, A. C., Jan 1 2015, In : OncoImmunology. 4, 4

Research output: Contribution to journalArticle

Terminology
T-Lymphocytes
Phenotype
Neoplasms
Tumor Microenvironment
Antigens
Antibodies
Neoplasms
Membrane Glycoproteins
Surface Antigens

Comparison of European bat rabies virus and fixed rabies virus protein sequences with respect to rabies virus pathogenesis and immunity

Wunner, W. H., Larson, J. K., Celis, E. & Dietzschold, B., Sep 1 1988, In : Virus Research. 11, SUPPL. 1, 1 p.

Research output: Contribution to journalArticle

Rabies virus
Immunity
Proteins
36 Citations (Scopus)

Combinatorial immunotherapy of polyinosinic-polycytidylic acid and blockade of programmed death-ligand 1 induce effective CD8 t-cell responses against established tumors

Nagato, T., Lee, Y. R., Harabuchi, Y. & Celis, E., Jan 1 2014, In : Clinical Cancer Research. 20, 5, p. 1223-1234 12 p.

Research output: Contribution to journalArticle

Poly I-C
Immunotherapy
Ligands
Neoplasms
Poly C
3 Citations (Scopus)

Combination cytokine therapy inhibits tumor growth by generation of tumor-specific T-cell responses in a murine melanoma model

Kalaaji, A. N., Lu, J., Markovic, S. N., Celis, E. & Pittelkow, M. R., Mar 1 2010, In : Cytokine. 49, 3, p. 287-293 7 p.

Research output: Contribution to journalArticle

T-cells
Granulocyte-Macrophage Colony-Stimulating Factor
Interferons
Tumors
Melanoma
18 Citations (Scopus)

c-Met is a novel tumor associated antigen for T-cell based immunotherapy against NK/T cell lymphoma

Kumai, T., Matsuda, Y., Ohkuri, T., Oikawa, K., Ishibashi, K., Aoki, N., Kimura, S., Harabuchi, Y., Celis, E. & Kobayashi, H., Jan 1 2015, In : OncoImmunology. 4, 2, p. 1-10 10 p.

Research output: Contribution to journalArticle

T-Cell Lymphoma
Neoplasm Antigens
Helper-Inducer T-Lymphocytes
Natural Killer Cells
Immunotherapy
202 Citations (Scopus)

Classification of current anticancer immunotherapies

Galluzzi, L., Vacchelli, E., Bravo-San Pedro, J. M., Buqué, A., Senovilla, L., Baracco, E. E., Bloy, N., Castoldi, F., Abastado, J. P., Agostinis, P., Apte, R. N., Aranda, F., Ayyoub, M., Beckhove, P., Blay, J. Y., Bracci, L., Caignard, A., Castelli, C., Cavallo, F., Celis, E. & 68 others, Cerundolo, V., Clayton, A., Colombo, M. P., Coussens, L., Dhodapkar, M. V., Eggermont, A. M., Fearon, D. T., Fridman, W. H., Fucíková, J., Gabrilovich, D. I., Galon, J., Garg, A., Ghiringhelli, F., Giaccone, G., Gilboa, E., Gnjatic, S., Hoos, A., Hosmalin, A., Jäger, D., Kalinski, P., Kärre, K., Kepp, O., Kiessling, R., Kirkwood, J. M., Klein, E., Knuth, A., Lewis, C. E., Liblau, R., Lotze, M. T., Lugli, E., Mach, J. P., Mattei, F., Mavilio, D., Melero, I., Melief, C. J., Mittendorf, E. A., Moretta, L., Odunsi, A., Okada, H., Palucka, A. K., Peter, M. E., Pienta, K. J., Porgador, A., Prendergast, G. C., Rabinovich, G. A., Restifo, N. P., Rizvi, N., Sautès-Fridman, C., Schreiber, H., Seliger, B., Shiku, H., Silva-Santos, B., Smyth, M. J., Speiser, D. E., Spisek, R., Srivastava, P. K., Talmadge, J. E., Tartour, E., Van Der Burg, S. H., Van Den Eynde, B. J., Vile, R., Wagner, H., Weber, J. S., Whiteside, T. L., Wolchok, J. D., Zitvogel, L., Zou, W. & Kroemer, G., Jan 1 2014, In : Oncotarget. 5, 24, p. 12472-12508 37 p.

Research output: Contribution to journalArticle

Immunotherapy
Immune System
Neoplasms
Neoplasm Antigens
United States Food and Drug Administration
268 Citations (Scopus)

Chemotherapy enhances tumor cell susceptibility to CTL-mediated killing during cancer immunotherapy in mice

Ramakrishnan, R., Assudani, D., Nagaraj, S., Hunter, T., Cho, H. I., Antonia, S., Altiok, S., Celis, E. & Gabrilovich, D. I., Apr 1 2010, In : Journal of Clinical Investigation. 120, 4, p. 1111-1124 14 p.

Research output: Contribution to journalArticle

Immunotherapy
Drug Therapy
Neoplasms
Cancer Vaccines
IGF Type 2 Receptor
4 Citations (Scopus)

Characterization of human CD4 helper T cell responses against Aurora kinase A

Kobayashi, H., Azumi, M., Hayashi, S., Sato, K., Aoki, N., Kimura, S., Kakizaki, H., Nagato, T., Harabuchi, Y., Tateno, M. & Celis, E., Jul 1 2010, In : Cancer Immunology, Immunotherapy. 59, 7, p. 1029-1039 11 p.

Research output: Contribution to journalArticle

Aurora Kinase A
Helper-Inducer T-Lymphocytes
Neoplasms
T-Lymphocyte Epitopes
Clone Cells
167 Citations (Scopus)

Cell-mediated immunological responses in cervical and vaginal cancer patients immunized with a lipidated epitope of human papillomavirus type 16 E7

Steller, M. A., Gurski, K. J., Murakami, M., Daniel, R. W., Shah, K. V., Celis, E., Sette, A., Trimble, E. L., Park, R. C. & Marincola, F. M., Sep 1 1998, In : Clinical Cancer Research. 4, 9, p. 2103-2109 7 p.

Research output: Contribution to journalArticle

Vaginal Neoplasms
Human papillomavirus 16
Uterine Cervical Neoplasms
Epitopes
Cellular Immunity
17 Citations (Scopus)

CCL17 and CCL22/CCR4 signaling is a strong candidate for novel targeted therapy against nasal natural killer/T-cell lymphoma

Kumai, T., Nagato, T., Kobayashi, H., Komabayashi, Y., Ueda, S., Kishibe, K., Ohkuri, T., Takahara, M., Celis, E. & Harabuchi, Y., Jun 6 2015, In : Cancer Immunology, Immunotherapy. 64, 6, p. 697-705 9 p.

Research output: Contribution to journalArticle

C Chemokines
Natural Killer T-Cells
T-Cell Lymphoma
Chemokine Receptors
Nose
Immunotherapy
Canada
Neoplasms
76 Citations (Scopus)

Blockade of LIGHT/LTβ and CD40 signaling induces allospecific T cell anergy, preventing graft-versus-host disease

Tamada, K., Tamura, H., Flies, D., Fu, Y. X., Celis, E., Pease, L. R., Blazar, B. R. & Chen, L., Jan 1 2002, In : Journal of Clinical Investigation. 109, 4, p. 549-557 9 p.

Research output: Contribution to journalArticle

Graft vs Host Disease
T-Lymphocytes
Light
Lymphotoxin-alpha
CD40 Ligand

Blockade of LIGHT/LTbeta and CD40 signaling induces allospecific T cell anergy, preventing graft-versus-host disease.

Tamada, K., Tamura, H., Flies, D., Fu, Y. X., Celis, E., Pease, L. R., Blazar, B. R. & Chen, L., Feb 1 2002, In : Journal of Clinical Investigation. 109, 4, p. 549-557 9 p.

Research output: Contribution to journalArticle

Graft vs Host Disease
Lymphotoxin beta Receptor
T-Lymphocytes
Light
CD40 Ligand
36 Citations (Scopus)

BiVax: A peptide/poly-IC subunit vaccine that mimics an acute infection elicits vast and effective anti-tumor CD8 T-cell responses

Cho, H. I., Barrios, K., Lee, Y. R., Linowski, A. K. & Celis, E., Apr 1 2013, In : Cancer Immunology, Immunotherapy. 62, 4, p. 787-799 13 p.

Research output: Contribution to journalArticle

Subunit Vaccines
T-Lymphocytes
Peptides
Infection
Neoplasms
30 Citations (Scopus)
T-Cell Antigen Receptor-CD3 Complex
Lymphokines
Phorbol Esters
Surface Antigens
T-Cell Antigen Receptor
43 Citations (Scopus)

Avoiding tolerance against prostatic antigens with subdominant peptide epitopes

Grossmann, M. E., Davila, E. & Celis, E., Jun 7 2001, In : Journal of Immunotherapy. 24, 3, p. 237-241 5 p.

Research output: Contribution to journalArticle

Prostate
Epitopes
Antigens
Peptides
Transgenic Mice
38 Citations (Scopus)

Autophagy induced by conventional chemotherapy mediates tumor cell sensitivity to immunotherapy

Ramakrishnan, R., Huang, C., Cho, H. I., Lloyd, M., Johnson, J., Ren, X., Altiok, S., Sullivan, D., Weber, J., Celis, E. & Gabrilovich, D. I., Nov 1 2012, In : Cancer Research. 72, 21, p. 5483-5493 11 p.

Research output: Contribution to journalArticle

Autophagy
Immunotherapy
Drug Therapy
IGF Type 2 Receptor
Neoplasms
167 Citations (Scopus)

Augmentation of T cell levels and responses induced by androgen deprivation

Roden, A. C., Moser, M. T., Tri, S. D., Mercader, M., Kuntz, S. M., Dong, H., Hurwitz, A. A., McKean, D. J., Celis, E., Leibovich, B. C., Allison, J. P. & Kwon, E. D., Nov 15 2004, In : Journal of Immunology. 173, 10, p. 6098-6108 11 p.

Research output: Contribution to journalArticle

Androgens
T-Lymphocytes
Immunity
Lymphocyte Depletion
Drug Therapy
9 Citations (Scopus)

A reproducible method for the enumeration of functional (cytokine producing) versus non-functional peptide-specific cytotoxic T lymphocytes in human peripheral blood

Markovic, S. N., Nevala, W. K., Uhl, C. B., Celis, E. & McKean, D. J., Sep 1 2006, In : Clinical and Experimental Immunology. 145, 3, p. 438-447 10 p.

Research output: Contribution to journalArticle

Cytotoxic T-Lymphocytes
Cytokines
Peptides
Antigen Presentation
HLA Antigens
26 Citations (Scopus)

A potent vaccination strategy that circumvents lymphodepletion for effective antitumor adoptive T-cell therapy

Cho, H. I., Reyes-Vargas, E., Delgado, J. C. & Celis, E., Apr 15 2012, In : Cancer Research. 72, 8, p. 1986-1995 10 p.

Research output: Contribution to journalArticle

Cell- and Tissue-Based Therapy
Interleukin-2
Vaccination
T-Lymphocytes
Whole-Body Irradiation
109 Citations (Scopus)

A phase I trial of an HLA-A1 restricted MAGE-3 epitope peptide with incomplete freund’s adjuvant in patients with resected high-risk melanoma

Weber, J. S., Hua, F. L., Spears, L., Marty, V., Kuniyoshi, C. & Celis, E., Jan 1 1999, In : Journal of Immunotherapy. 22, 5, p. 431-440 10 p.

Research output: Contribution to journalArticle

HLA-A1 Antigen
Epitopes
Melanoma
Peptides
Vaccines
132 Citations (Scopus)

Antimicrobial activity of MHC class I-restricted CD8+ T cells in human tuberculosis

Cho, S., Mehra, V., Thoma-Uszynski, S., Stenger, S., Serbina, N., Mazzaccaro, R. J., Flynn, J. L., Barnes, P. F., Southwood, S., Celis, E., Bloom, B. R., Modlin, R. L. & Sette, A., Oct 24 2000, In : Proceedings of the National Academy of Sciences of the United States of America. 97, 22, p. 12210-12215 6 p.

Research output: Contribution to journalArticle

Tuberculosis
T-Lymphocytes
Epitopes
Mycobacterium tuberculosis
Cytotoxic T-Lymphocytes
6 Citations (Scopus)

Antigen-induced production of lymphokines by human T cell clones specific for hepatitis B surface antigen

Celis, E., Miller, R. W. & Tse wen, C., Dec 1984, In : Human Immunology. 11, 4, p. 229-237 9 p.

Research output: Contribution to journalArticle

Lymphokines
Hepatitis B Surface Antigens
Interleukin-2
Clone Cells
T-Lymphocytes
20 Citations (Scopus)

Antigen-independent acquisition of MHC class II molecules by human T lymphocytes

Undale, A. H., van den Elsen, P. J. & Celis, E., Oct 1 2004, In : International Immunology. 16, 10, p. 1523-1533 11 p.

Research output: Contribution to journalArticle

T-Lymphocytes
Antigens
Antigen-Presenting Cells
Histocompatibility Antigens Class II
Cell Adhesion Molecules
28 Citations (Scopus)

Antigenic variation in rabies and rabies-related viruses: cross-protection independent of glycoprotein-mediated virus-neutralizing antibody

Dietzschold, B., Tollis, M., Rupprecht, C. E., Celis, E. & Koprowski, H., Jan 1 1987, In : Journal of Infectious Diseases. 156, 5, p. 815-822 8 p.

Research output: Contribution to journalArticle

Cross Protection
Antigenic Variation
Rabies virus
Rabies
Neutralizing Antibodies
83 Citations (Scopus)

Antibodies to hepatitis B surface antigen potentiate the response of human T lymphocyte clones to the same antigen

Celis, E. & Chang, T. W., Jan 1 1984, In : Science. 224, 4646, p. 297-299 3 p.

Research output: Contribution to journalArticle

Hepatitis B Surface Antigens
Clone Cells
T-Lymphocytes
Antigens
Hepatitis B virus
10 Citations (Scopus)

A novel combinatorial cancer immunotherapy: Poly-IC and blockade of the PD-1/PD-L1 pathway

Nagato, T. & Celis, E., Jan 1 2014, In : OncoImmunology. 3, 5, e28440.

Research output: Contribution to journalArticle

Immunotherapy
Cell Death
Neoplasms
Blocking Antibodies
T-Lymphocytes
5 Citations (Scopus)

An osteopontin/CD44 immune checkpoint controls CD8+ T cell activation and tumor immune evasion

Klement, J. D., Paschall, A. V., Redd, P. S., Ibrahim, M. L., Lu, C., Yang, D., Celis, E., Abrams, S. I., Ozato, K. & Liu, K., Dec 3 2018, In : Journal of Clinical Investigation. 128, 12, p. 5549-5560 12 p.

Research output: Contribution to journalArticle

Tumor Escape
Osteopontin
T-Lymphocytes
Immunotherapy
Colon
15 Citations (Scopus)

An optimized peptide vaccine strategy capable of inducing multivalent CD8+ T cell responses with potent antitumor effects

Cho, H. I., Jung, S. H., Sohn, H. J., Celis, E. & Kim, T. G., Nov 2 2015, In : OncoImmunology. 4, 11

Research output: Contribution to journalArticle

Subunit Vaccines
T-Lymphocytes
Neoplasms
Cancer Vaccines
Vaccination
7 Citations (Scopus)

A naturally processed HLA-DR-bound peptide from the IL-9 receptor alpha of HTLV-1-transformed T cells serves as a T helper epitope

Kobayashi, H., Kumai, T., Hayashi, S., Matsuda, Y., Aoki, N., Sato, K., Kimura, S. & Celis, E., Dec 1 2012, In : Cancer Immunology, Immunotherapy. 61, 12, p. 2215-2225 11 p.

Research output: Contribution to journalArticle

Interleukin-9 Receptors
Deltaretrovirus
HLA-DR Antigens
Epitopes
Adult T Cell Leukemia Lymphoma
6 Citations (Scopus)

Analysis of MHC-specific peptide motifs: Applications in immunotherapy

Loftus, D. J., Kubo, R. T., Sakaguchi, K., Celis, E., Sette, A. & Appella, E., Jan 1 1995, In : Advances in experimental medicine and biology. 383, p. 201-210 10 p.

Research output: Contribution to journalArticle

Immunotherapy
Peptides
Molecules
Epitopes
Guidelines
28 Citations (Scopus)

Amplification of rabies virus-induced stimulation of human T-cell lines and clones by antigen-specific antibodies

Celis, E., Wiktor, T. J., Dietzschold, B. & Koprowski, H., Dec 1 1985, In : Journal of Virology. 56, 2, p. 426-433 8 p.

Research output: Contribution to journalArticle

Rabies virus
Rabies
rabies
Clone Cells
T-lymphocytes
123 Citations (Scopus)

Altered helper T lymphocyte function associated with chronic hepatitis B virus infection and its role in response to therapeutic vaccination in humans

Livingston, B. D., Alexander, J., Crimi, C., Oseroff, C., Celis, E., Daly, K., Guidotti, L. G., Chisari, F. V., Fikes, J., Chesnut, R. W. & Sette, A., Mar 1 1999, In : Journal of Immunology. 162, 5, p. 3088-3095 8 p.

Research output: Contribution to journalArticle

Chronic Hepatitis B
Virus Diseases
Helper-Inducer T-Lymphocytes
Hepatitis B virus
Vaccination
38 Citations (Scopus)

Adoptive transfer of Tc1 or Tc17 cells elicits antitumor immunity against established melanoma through distinct mechanisms

Yu, Y., Hyun-II Cho, C., Wang, D., Kaosaard, K., Anasetti, C., Celis, E. & Yu, X. Z., Feb 15 2013, In : Journal of Immunology. 190, 4, p. 1873-1881 9 p.

Research output: Contribution to journalArticle

Adoptive Transfer
Immunity
Melanoma
Interleukin-17
Neoplasms
915 Citations (Scopus)
CD8 Antigens
Cell- and Tissue-Based Therapy
Melanoma
Clone Cells
T-Lymphocytes