• 11943 Citations
  • 55 h-Index
1973 …2020

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2002

Enhancing immunogenicity of a CTL epitope from carcinoembryonic antigen by selective amino acid replacements

Huarte, E., Sarobe, P., Lu, J., Casares, N., Lasarte, J. J., Dotor, J., Ruiz, M., Prieto, J., Celis, E. & Borrás-Cuesta, F., Jan 1 2002, In : Clinical Cancer Research. 8, 7, p. 2336-2344 9 p.

Research output: Contribution to journalArticle

26 Scopus citations

Identification of an antigenic epitope for helper T lymphocytes from carcinoembryonic antigen

Kobayashi, H., Omiya, R., Ruiz, M., Huarte, E., Sarobe, P., Lasarte, J. J., Herraiz, M., Sangro, B., Prieto, J., Borras-Cuesta, F. & Celis, E., Oct 1 2002, In : Clinical Cancer Research. 8, 10, p. 3219-3225 7 p.

Research output: Contribution to journalArticle

49 Scopus citations

Inhibition of EBV-induced lymphoproliferation by CD4+ T cells specific for an MHC class II promiscuous epitope

Omiya, R., Buteau, C., Kobayashi, H., Paya, C. V. & Celis, E., Aug 15 2002, In : Journal of Immunology. 169, 4, p. 2172-2179 8 p.

Research output: Contribution to journalArticle

65 Scopus citations

Interleukin 15 promotes antigen-independent in vitro expansion and long-term survival of antitumor cytotoxic T lymphocytes

Lu, J., Giuntoli, R. L., Omiya, R., Kobayashi, H., Kennedy, R. & Celis, E., Dec 1 2002, In : Clinical Cancer Research. 8, 12, p. 3877-3884 8 p.

Research output: Contribution to journalArticle

50 Scopus citations

Recognition of prostate tumor cells by cytotoxic T lymphocytes specific for prostate-specific membrane antigen

Lu, J. & Celis, E., Oct 15 2002, In : Cancer Research. 62, 20, p. 5807-5812 6 p.

Research output: Contribution to journalArticle

84 Scopus citations
2001

Avoiding tolerance against prostatic antigens with subdominant peptide epitopes

Grossmann, M. E., Davila, E. & Celis, E., Jun 7 2001, In : Journal of Immunotherapy. 24, 3, p. 237-241 5 p.

Research output: Contribution to journalArticle

44 Scopus citations

Existence of MHC class I-restricted alloreactive CD4+ T cells reacting with peptide transporter-deficient cells

Kobayashi, H., Kimura, S., Aoki, N., Sato, K., Celis, E. & Katagiri, M., Jan 1 2001, In : Immunogenetics. 53, 8, p. 626-633 8 p.

Research output: Contribution to journalArticle

9 Scopus citations

Expression, specificity and immunotherapy potential of prostate-associated genes in murine cell lines

Grossmann, M. E., Wood, M. & Celis, E., Jan 1 2001, In : World Journal of Urology. 19, 5, p. 365-370 6 p.

Research output: Contribution to journalArticle

20 Scopus citations

Identification of helper T-cell epitopes that encompass or lie proximal to cytotoxic T-cell epitopes in the gp100 melanoma tumor antigen

Kobayashi, H., Lu, J. & Celis, E., Oct 15 2001, In : Cancer Research. 61, 20, p. 7577-7584 8 p.

Research output: Contribution to journalArticle

66 Scopus citations

Identification of new epitopes from four different tumor-associated antigens: Recognition of naturally processed epitopes correlates with HLA-A*0201-binding affinity

Keogh, E., Fikes, J., Southwood, S., Celis, E., Chesnut, R. & Sette, A., Jul 15 2001, In : Journal of Immunology. 167, 2, p. 787-796 10 p.

Research output: Contribution to journalArticle

118 Scopus citations

TAP-independent presentation of CTL epitopes by Trojan antigens

Lu, J., Wettstein, P. J., Higashimoto, Y., Appella, E. & Celis, E., Jun 15 2001, In : Journal of Immunology. 166, 12, p. 7063-7071 9 p.

Research output: Contribution to journalArticle

57 Scopus citations

Tum-or-reactive T helper lymphocytes recognize a promiscuous MAGE-A3 epitope presented by various major histocompatibility complex class II alleles

Kobayashi, H., Song, Y., Hoon, D. S. B., Appella, E. & Celis, E., Jun 15 2001, In : Cancer Research. 61, 12, p. 4773-4778 6 p.

Research output: Contribution to journalArticle

70 Scopus citations
2000

Antimicrobial activity of MHC class I-restricted CD8+ T cells in human tuberculosis

Cho, S., Mehra, V., Thoma-Uszynski, S., Stenger, S., Serbina, N., Mazzaccaro, R. J., Flynn, J. L., Barnes, P. F., Southwood, S., Celis, E., Bloom, B. R., Modlin, R. L. & Sette, A., Oct 24 2000, In : Proceedings of the National Academy of Sciences of the United States of America. 97, 22, p. 12210-12215 6 p.

Research output: Contribution to journalArticle

134 Scopus citations

Defining promiscuous MHC class II helper T-cell epitopes for the HER2/neu tumor antigen

Kobayashi, H., Wood, M., Song, Y., Appella, E. & Celis, E., Sep 15 2000, In : Cancer Research. 60, 18, p. 5228-5236 9 p.

Research output: Contribution to journalArticle

121 Scopus citations

Detection of t helper responses, but not of human papillomavirus-specific cytotoxic t lymphocyte responses, after peptide vaccination of patients with cervical carcinoma

Ressing, M. E., van Driel, W. J., Brandt, R. M. P., Kenter, G. G., de Jong, J. H., Bauknecht, T., Fleuren, G. J., Hoogerhout, P., Offringa, R., Sette, A., Celis, E., Grey, H., Trimbos, B. J., Kast, W. M. & Melief, C. J. M., Jan 1 2000, In : Journal of Immunotherapy. 23, 2, p. 255-266 12 p.

Research output: Contribution to journalArticle

151 Scopus citations

Identification of HLA-A*03, A*11 and B*07-restricted melanoma-associated peptides that are immunogenic in vivo by vaccine-induced immune response (VIIR) analysis

Reynolds, S. R., Celis, E., Sette, A., Oratz, R., Shapiro, R. L., Johnston, D., Fotino, M. & Bystryn, J. C., Oct 20 2000, In : Journal of Immunological Methods. 244, 1-2, p. 59-67 9 p.

Research output: Contribution to journalArticle

20 Scopus citations

MHC-binding peptides as immunotherapeutics for cancer

Kobayashi, H., Kennedy, R., Lu, J., Davila, E. & Celis, E., Jan 1 2000, In : Immunological Investigations. 29, 2, p. 105-110 6 p.

Research output: Contribution to journalArticle

7 Scopus citations
128 Scopus citations

Tumor prevention and antitumor immunity with heat shock protein 70 induced by 15-deoxy-Δ12,14-prostaglandin J2 in transgenic adenocarcinoma of mouse prostate cells

Vanaja, D. K., Grossmann, M. E., Celis, E. & Young, C. Y. F., Sep 1 2000, In : Cancer Research. 60, 17, p. 4714-4718 5 p.

Research output: Contribution to journalArticle

41 Scopus citations

Use of two predictive algorithms of the world wide web for the identification of tumor-reactive T-cell epitopes

Lu, J. & Celis, E., Sep 15 2000, In : Cancer Research. 60, 18, p. 5223-5227 5 p.

Research output: Contribution to journalArticle

65 Scopus citations
1999

Altered helper T lymphocyte function associated with chronic hepatitis B virus infection and its role in response to therapeutic vaccination in humans

Livingston, B. D., Alexander, J., Crimi, C., Oseroff, C., Celis, E., Daly, K., Guidotti, L. G., Chisari, F. V., Fikes, J., Chesnut, R. W. & Sette, A., Mar 1 1999, In : Journal of Immunology. 162, 5, p. 3088-3095 8 p.

Research output: Contribution to journalArticle

123 Scopus citations

A phase I trial of an HLA-A1 restricted MAGE-3 epitope peptide with incomplete freund’s adjuvant in patients with resected high-risk melanoma

Weber, J. S., Hua, F. L., Spears, L., Marty, V., Kuniyoshi, C. & Celis, E., Jan 1 1999, In : Journal of Immunotherapy. 22, 5, p. 431-440 10 p.

Research output: Contribution to journalArticle

110 Scopus citations

Identification of a MAGE-2-encoded human leukocyte antigen-A24-binding synthetic peptide that induces specific antitumor cytotoxic T lymphocytes

Tahara, K., Takesako, K., Sette, A., Celis, E., Kitano, S. & Akiyoshi, T., Aug 1 1999, In : Clinical Cancer Research. 5, 8, p. 2236-2241 6 p.

Research output: Contribution to journalArticle

33 Scopus citations

Identification of HLA-A24 epitope peptides of carcinoembryonic antigen which induce tumor-reactive cytotoxic T lymphocyte

Nukaya, I., Yasumoto, M., Iwasaki, T., Ideno, M., Sette, A., Celis, E., Takesako, K. & Kato, I., Jan 5 1999, In : International Journal of Cancer. 80, 1, p. 92-97 6 p.

Research output: Contribution to journalArticle

103 Scopus citations

Identification of HLA-A3-restricted cytotoxic T lymphocyte epitopes from carcinoembryonic antigen and HER-2/neu by primary in vitro immunization with peptide-pulsed dendritic cells

Kawashima, I., Tsai, V., Southwood, S., Takesako, K., Sette, A. & Celis, E., Jan 16 1999, In : Cancer Research. 59, 2, p. 431-435 5 p.

Research output: Contribution to journalArticle

121 Scopus citations

Identification of new HER2/neu-derived peptide epitopes that can elicit specific CTL against autologous and allogeneic carcinomas and melanomas

Rongcun, Y., Salazar-Onfray, F., Charo, J., Malmberg, K. J., Evrin, K., Maes, H., Kono, K., Hising, C., Petersson, M., Larsson, O., Lan, L., Appella, E., Sette, A., Celis, E. & Kiessling, R., Jul 15 1999, In : Journal of Immunology. 163, 2, p. 1037-1044 8 p.

Research output: Contribution to journalArticle

164 Scopus citations
1998

Cell-mediated immunological responses in cervical and vaginal cancer patients immunized with a lipidated epitope of human papillomavirus type 16 E7

Steller, M. A., Gurski, K. J., Murakami, M., Daniel, R. W., Shah, K. V., Celis, E., Sette, A., Trimble, E. L., Park, R. C. & Marincola, F. M., Sep 1 1998, In : Clinical Cancer Research. 4, 9, p. 2103-2109 7 p.

Research output: Contribution to journalArticle

169 Scopus citations

HLA-independent heterogeneity of CD8+ T cell responses to MAGE-3, Melan-A/MART-1, gp100, tyrosinase, MC1R, and TRP-2 in vaccine-treated melanoma patients

Reynolds, S. R., Celis, E., Sette, A., Oratz, R., Shapiro, R. L., Johnston, D., Fotino, M. & Bystryn, J. C., Dec 15 1998, In : Journal of Immunology. 161, 12, p. 6970-6976 7 p.

Research output: Contribution to journalArticle

74 Scopus citations

Identification of GP100-derived, melanoma-specific cytotoxic T- lymphocyte epitopes restricted by HLA-A3 supertype molecules by primary in vitro immunization with peptide-pulsed dendritic cells

Kawashtma, I., Tsai, V., Southwood, S., Takesako, K., Celis, E. & Sette, A., Nov 2 1998, In : International Journal of Cancer. 78, 4, p. 518-524 7 p.

Research output: Contribution to journalArticle

39 Scopus citations

Identification of HER2/neu-derived peptide epitopes recognized by gastric cancer-specific cytotoxic T lymphocytes

Kono, K., Rongcun, Y., Charo, J., Ichihara, F., Celis, E., Sette, A., Appella, E., Sekikawa, T., Matsumoto, Y. & Kiessung, R., Oct 8 1998, In : International Journal of Cancer. 78, 2, p. 202-208 7 p.

Research output: Contribution to journalArticle

76 Scopus citations

Pools of lipidated HTL-CTL constructs prime for multiple HBV and HCV CTL epitope responses

Oseroff, C., Sette, A., Wentworth, P., Celis, E., Maewal, A., Dahlberg, C., Fikes, J., Kubo, R. T., Chesnut, R. W., Grey, H. M. & Alexander, J., May 1 1998, In : Vaccine. 16, 8, p. 823-833 11 p.

Research output: Contribution to journalArticle

36 Scopus citations

Role of preimmunization virus sequences in cellular immunity in HIV- infected patients during HIV type 1 MN recombinant gp160 immunization

Kundu, S. K., Dupuis, M., Sette, A., Celis, E., Dorner, F., Eibl, M. & Merigan, T. C., Jan 1 1998, In : AIDS Research and Human Retroviruses. 14, 18, p. 1669-1678 10 p.

Research output: Contribution to journalArticle

15 Scopus citations

Specific T cell recognition of peptides derived from prostate-specific antigen in patients with prostate cancer

Alexander, R. B., Brady, F., Leffell, M. S., Tsai, V. & Celis, E., Jan 1 1998, In : Urology. 51, 1, p. 150-157 8 p.

Research output: Contribution to journalArticle

39 Scopus citations

The multi-epitope approach for immunotherapy for cancer: Identification of several CTL epitopes from various tumor-associated antigens expressed on solid epithelial tumors

Kawashima, I., Hudson, S. J., Tsai, V., Southwood, S., Takesako, K., Appella, E., Sette, A. & Celis, E., Jan 1 1998, In : Human Immunology. 59, 1, p. 1-14 14 p.

Research output: Contribution to journalArticle

196 Scopus citations
1997

Identification of Subdominant CTL Epitopes of the GP100 Melanoma-Associated Tumor Antigen by Primary in Vitro Immunization with Peptide-Pulsed Dendritic Cells

Tsai, V., Southwood, S., Sidney, J., Sakaguchi, K., Kawakami, Y., Appella, E., Sette, A. & Celis, E., Feb 15 1997, In : Journal of Immunology. 158, 4, p. 1796-1802 7 p.

Research output: Contribution to journalArticle

165 Scopus citations

Induction of antitumor cytotoxic T lymphocytes with a MAGE-3-encoded synthetic peptide presented by human leukocytes antigen-A24

Tanaka, F., Fujie, T., Tahara, K., Mori, M., Takesako, K., Sette, A., Celis, E. & Akiyoshi, T., Oct 15 1997, In : Cancer Research. 57, 20, p. 4465-4468 4 p.

Research output: Contribution to journalArticle

95 Scopus citations

In vitro immunization and expansion of antigen-specific cytotoxic T lymphocytes for adoptive immunotherapy using peptide-pulsed dendritic cells

Tsai, V., Kawashima, I., Keogh, E., Daly, K., Sette, A. & Celis, E., Jan 1 1997, In : Critical Reviews in Immunology. 18, 1-2, p. 65-75 11 p.

Research output: Contribution to journalArticle

60 Scopus citations

Synthetic peptides derived from the melanocyte-stimulating hormone receptor MC1R can stimulate HLA-A2-restricted cytotoxic T lymphocytes that recognize naturally processed peptides on human melanoma cells

Salazar-Onfray, F., Nakazawa, T., Chhajlani, V., Petersson, M., Kärre, K., Masucci, G., Celis, E., Sette, A., Southwood, S., Appella, E. & Kiessling, R., Oct 1 1997, In : Cancer Research. 57, 19, p. 4348-4355 8 p.

Research output: Contribution to journalArticle

49 Scopus citations

Two distinct HLA-A*0101-specific submotifs illustrate alternative peptide binding modes

Kondo, A., Sidney, J., Southwood, S., Del Guercio, M. F., Appella, E., Sakamoto, H., Grey, H. M., Celis, E., Chesnut, R. W., Kubo, R. T. & Sette, A., Jan 1 1997, In : Immunogenetics. 45, 4, p. 249-258 10 p.

Research output: Contribution to journalArticle

27 Scopus citations
1996

Definition of an HLA-A3-like supermotif demonstrates the overlapping peptide-binding repertoires of common HLA molecules

Sidney, J., Grey, H. M., Southwood, S., Celis, E., Wentworth, P. A., Del Guercio, M. F., Kubo, R. T., Chesnut, R. W. & Sette, A., Jan 1 1996, In : Human Immunology. 45, 2, p. 79-93 15 p.

Research output: Contribution to journalArticle

187 Scopus citations

Generation of tumor-specific cytolytic T lymphocytes from peripheral blood of cervical cancer patients by in vitro stimulation with a synthetic human papillomavirus type 16 E7 epitope

Alexander, M., Salgaller, M. L., Celis, E., Sette, A., Barnes, W. A., Rosenberg, S. A. & Steller, M. A., Jan 1 1996, In : American journal of obstetrics and gynecology. 175, 6, p. 1586-1593 8 p.

Research output: Contribution to journalArticle

88 Scopus citations

Identification of A2-restricted hepatitis C virus-specific cytotoxic T lymphocyte epitopes from conserved regions of the viral genome

Wentworth, P. A., Sette, A., Celis, E., Sidney, J., Southwood, S., Crimi, C., Stitely, S., Keogh, E., Wong, N. C., Livingston, B., Alazard, D., Vitiello, A., Grey, H. M., Chisari, F. V., Chesnut, R. W. & Fikes, J., Jan 1 1996, In : International Immunology. 8, 5, p. 651-659 9 p.

Research output: Contribution to journalArticle

65 Scopus citations

Substitutions in the HLA-DRα chain differentially affect DR7-restricted T-cell recognition of rabies virus antigen

Fu, X. T., Saibara, T., Karr, R. W. & Celis, E., Feb 1996, In : Human Immunology. 45, 2, p. 111-116 6 p.

Research output: Contribution to journalArticle

1 Scopus citations
1995

Analysis of MHC-specific peptide motifs: Applications in immunotherapy

Loftus, D. J., Kubo, R. T., Sakaguchi, K., Celis, E., Sette, A. & Appella, E., Jan 1 1995, In : Advances in experimental medicine and biology. 383, p. 201-210 10 p.

Research output: Contribution to journalArticle

6 Scopus citations

Epitope selection and development of peptide based vaccines to treat cancer

Celis, E., Sette, A. & Grey, H. M., Jan 1 1995, In : Seminars in Cancer Biology. 6, 6, p. 329-336 8 p.

Research output: Contribution to journalArticle

48 Scopus citations

In vitro induction of primary, antigen-specific CTL from human peripheral blood mononuclear cells stimulated with synthetic peptides

Wentworth, P. A., Celis, E., Crimi, C., Stitely, S., Hale, L., Tsai, V., Serra, H. M., Guercio, M. F. D., Livingston, B., Alazard, D., Fikes, J., Kubo, R. T., Grey, H. M., Chesnut, R. W., Chisari, F. V. & Sette, A., Jan 1 1995, In : Molecular Immunology. 32, 9, p. 603-612 10 p.

Research output: Contribution to journalArticle

48 Scopus citations

Patients with chronic hepatitis C have circulating cytotoxic T cells which recognize hepatitis C virus-encoded peptides binding to HLA-A2.1 molecules

Battegay, M., Fikes, J., Di Bisceglie, A. M., Wentworth, P. A., Sette, A., Celis, E., Ching, W. M., Grakoui, A., Rice, C. M., Kurokohchi, K., Berzofsky, J. A., Hoofnagle, J. H., Feinstone, S. M. & Akatsuka, T., Jan 1 1995, In : Journal of Virology. 69, 4, p. 2462-2470 9 p.

Research output: Contribution to journalArticle

205 Scopus citations

Prominent roles of secondary anchor residues in peptide binding to HLA- A24 human class I molecules

Kondo, A., Sidney, J., Southwood, S., Del Guercio, M. F., Appella, E., Sakamoto, H., Celis, E., Grey, H. M., Chesnut, R. W., Kubo, R. T. & Sette, A., Jan 1 1995, In : Journal of Immunology. 155, 9, p. 4307-4312 6 p.

Research output: Contribution to journalArticle

77 Scopus citations
1994

Identification of potential CTL epitopes of tumor-associated antigen MAGE-1 for five common HLA-A alleles

Celis, E., Fikes, J., Wentworth, P., Sidney, J., Southwood, S., Maewal, A., Del Guercio, M. F., Sette, A. & Livingston, B., Dec 1994, In : Molecular Immunology. 31, 18, p. 1423-1430 8 p.

Research output: Contribution to journalArticle

59 Scopus citations

Induction of anti-tumor cytotoxic T lymphocytes in normal humans using primary cultures and synthetic peptide epitopes

Celis, E., Tsai, V., Crimi, C., Demars, R., Wentworth, P. A., Chesnut, R. W., Grey, H. M., Sette, A. & Serra, H. M., Mar 15 1994, In : Proceedings of the National Academy of Sciences of the United States of America. 91, 6, p. 2105-2109 5 p.

Research output: Contribution to journalArticle

293 Scopus citations