James R Gossage

Professor - Part Time

  • 1505 Citations
  • 15 h-Index
1992 …2019
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Research Output 1992 2019

2019
11 Citations (Scopus)

Pazopanib may reduce bleeding in hereditary hemorrhagic telangiectasia

Faughnan, M. E., Gossage, J. R., Chakinala, M. M., Oh, S. P., Kasthuri, R., Hughes, C. C. W., McWilliams, J. P., Parambil, J. G., Vozoris, N., Donaldson, J., Paul, G., Berry, P. & Sprecher, D. L., Feb 15 2019, In : Angiogenesis. 22, 1, p. 145-155 11 p.

Research output: Contribution to journalArticle

Hereditary Hemorrhagic Telangiectasia
Epistaxis
Hemorrhage
Hemoglobins
Health
2018
1 Citation (Scopus)

Association of common candidate variants with vascular malformations and intracranial hemorrhage in hereditary hemorrhagic telangiectasia

the Brain Vascular Malformation Consortium HHT Investigator Group, May 1 2018, In : Molecular Genetics and Genomic Medicine. 6, 3, p. 350-356 7 p.

Research output: Contribution to journalArticle

Hereditary Hemorrhagic Telangiectasia
Vascular Malformations
Intracranial Hemorrhages
Arteriovenous Malformations
Central Nervous System Vascular Malformations
Hereditary Hemorrhagic Telangiectasia
Hemorrhage
Bevacizumab
2017
3 Citations (Scopus)

Prevalence and predictors of anemia in hereditary hemorrhagic telangiectasia

the Brain Vascular Malformation Consortium HHT Investigator Group, Oct 1 2017, In : American Journal of Hematology. 92, 10, p. E591-E593

Research output: Contribution to journalLetter

8 Citations (Scopus)

Pulmonary arteriovenous malformations: Evidence of physician under-education

Shovlin, C. L. & Gossage, J. R., Apr 1 2017, In : ERS Monograph. 3, 2, 00104-2016.

Research output: Contribution to journalLetter

Arteriovenous Malformations
Physicians
Education
Lung
2016
29 Citations (Scopus)

Effect of topical intranasal therapy on epistaxis frequency in patients with hereditary hemorrhagic telangiectasia: A randomized clinical trial

Whitehead, K. J., Sautter, N. B., McWilliams, J. P., Chakinala, M. M., Merlo, C. A., Johnson, M. H., James, M., Everett, E. M., Clancy, M. S., Faughnan, M. E., Oh, S. P., Olitsky, S. E., Pyeritz, R. E. & Gossage, J. R., Jan 1 2016, In : JAMA - Journal of the American Medical Association. 316, 9, p. 943-951 9 p.

Research output: Contribution to journalArticle

Hereditary Hemorrhagic Telangiectasia
Epistaxis
Randomized Controlled Trials
Tranexamic Acid
Estriol
2015
24 Citations (Scopus)

Clinical implications of pulmonary shunting on saline contrast echocardiography

Velthuis, S., Buscarini, E., Gossage, J. R., Snijder, R. J., Mager, J. J. & Post, M. C., Jan 1 2015, In : Journal of the American Society of Echocardiography. 28, 3, p. 255-263 9 p.

Research output: Contribution to journalArticle

Echocardiography
Lung
Hereditary Hemorrhagic Telangiectasia
Arteriovenous Malformations
Antibiotic Prophylaxis
18 Citations (Scopus)

Executive summary of the 11th HHT international scientific conference

Arthur, H., Geisthoff, U., Gossage, J. R., Hughes, C. C. W., Lacombe, P., Meek, M. E., Oh, P., Roman, B. L., Trerotola, S. O., Velthuis, S. & Wooderchak-Donahue, W., Oct 1 2015, In : Angiogenesis. 18, 4, p. 511-524 14 p.

Research output: Contribution to journalArticle

Activin Receptors
Hereditary Hemorrhagic Telangiectasia
Moderators
Vascular Malformations
Islands
12 Citations (Scopus)

Mutations in RASA1 and GDF2 identified in patients with clinical features of hereditary hemorrhagic telangiectasia

Hernandez, F., Huether, R., Carter, L., Johnston, T., Thompson, J., Gossage, J. R., Chao, E. & Elliott, A. M., Nov 5 2015, In : Human Genome Variation. 2, 15040.

Research output: Contribution to journalArticle

Open Access
Hereditary Hemorrhagic Telangiectasia
Genes
Mutation
Bone Morphogenetic Proteins
Transforming Growth Factor beta
5 Citations (Scopus)

The ACVRL1 c.314-35A>G polymorphism is associated with organ vascular malformations in hereditary hemorrhagic telangiectasia patients with ENG mutations, but not in patients with ACVRL1 mutations

the Brain Vascular Malformation Consortium HHT Investigator Group, Jun 1 2015, In : American Journal of Medical Genetics, Part A. 167, 6, p. 1262-1267 6 p.

Research output: Contribution to journalArticle

Hereditary Hemorrhagic Telangiectasia
Vascular Malformations
Mutation
Arteriovenous Malformations
Lung
2014
20 Citations (Scopus)

Cerebral vascular malformations in hereditary hemorrhagic telangiectasia: Clinical article

Woodall, M. N., McGettigan, M., Figueroa Ortiz, R. E., Gossage, J. R. & Alleyne, C. H., Jan 1 2014, In : Journal of neurosurgery. 120, 1, p. 87-92 6 p.

Research output: Contribution to journalArticle

Hereditary Hemorrhagic Telangiectasia
Vascular Malformations
Arteriovenous Malformations
Magnetic Resonance Angiography
Telangiectasis
13 Citations (Scopus)

Pulmonary vascular complications of hereditary haemorrhagic telangiectasia

Circo, S. & Gossage, J. R., Jan 1 2014, In : Current Opinion in Pulmonary Medicine. 20, 5, p. 421-428 8 p.

Research output: Contribution to journalReview article

Hereditary Hemorrhagic Telangiectasia
Blood Vessels
Pulmonary Hypertension
Lung
Arteriovenous Malformations
2012
27 Citations (Scopus)

Age-dependent lethality in novel transgenic mouse models of central nervous system arteriovenous malformations

Milton, I., Ouyang, D., Allen, C. J., Yanasak, N. E., Gossage, J. R., Alleyne, C. H. & Seki, T., May 1 2012, In : Stroke. 43, 5, p. 1432-1435 4 p.

Research output: Contribution to journalArticle

Nervous System Malformations
Arteriovenous Malformations
Transgenic Mice
Central Nervous System
Hemorrhage
31 Citations (Scopus)

Brain arteriovenous malformations associated with hereditary hemorrhagic telangiectasia: Gene-phenotype correlations

Nishida, T., Faughnan, M. E., Krings, T., Chakinala, M., Gossage, J. R., Young, W. L., Kim, H., Pourmohamad, T., Henderson, K. J., Schrum, S. D., James, M., Quinnine, N., Bharatha, A., terBrugge, K. G. & White, R. I., Nov 1 2012, In : American Journal of Medical Genetics, Part A. 158 A, 11, p. 2829-2834 6 p.

Research output: Contribution to journalArticle

Hereditary Hemorrhagic Telangiectasia
Arteriovenous Malformations
Intracranial Hemorrhages
Phenotype
Brain

Pulmonary Arteriovenous Malformations

Kaushik, S. & Gossage, J. R., Jan 13 2012, Pediatric Cardiovascular Medicine: Second Edition. Wiley-Blackwell, p. 660-666 7 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Arteriovenous Malformations
Lung
Hereditary Hemorrhagic Telangiectasia
Echocardiography
Therapeutic Embolization
2011
19 Citations (Scopus)
Hereditary Hemorrhagic Telangiectasia
Nasal Sprays
Polyethylene
Benzalkonium Compounds
Therapeutics
505 Citations (Scopus)

International guidelines for the diagnosis and management of hereditary haemorrhagic telangiectasia

Faughnan, M. E., Palda, V. A., Garcia-Tsao, G., Geisthoff, U. W., McDonald, J., Proctor, D. D., Spears, J., Brown, D. H., Buscarini, E., Chesnutt, M. S., Cottin, V., Ganguly, A., Gossage, J. R., Guttmacher, A. E., Hyland, R. H., Kennedy, S. J., Korzenik, J., Mager, J. J., Ozanne, A. P., Piccirillo, J. F. & 13 others, Picus, D., Plauchu, H., Porteous, M. E. M., Pyeritz, R. E., Ross, D. A., Sabba, C., Swanson, K., Terry, P., Wallace, M. C., Westermann, C. J. J., White, R. I., Young, L. H. & Zarrabeitia, R., Feb 1 2011, In : Journal of medical genetics. 48, 2, p. 73-87 15 p.

Research output: Contribution to journalReview article

Hereditary Hemorrhagic Telangiectasia
Guidelines
Patient Advocacy
Consensus
Delivery of Health Care
2010
2 Citations (Scopus)

A 31-year-old man with liver transplant and progressive jaundice

Kaushik, S. & Gossage, J. R., Aug 1 2010, In : Chest. 138, 2, p. 448-451 4 p.

Research output: Contribution to journalArticle

Jaundice
Transplants
Liver
13 Citations (Scopus)
Hereditary Hemorrhagic Telangiectasia
Arteriovenous Malformations
Echocardiography
Lung
3 Citations (Scopus)

Second allo-SCT from a different donor can improve severe steroid-resistant gut GVHD

Ustun, C., Jillella, A., Shah, R., Sterling, K., Deremer, D., Savage, N., Awan, F., Gossage, J. R., Dillard, T. & Martin, P. J., Nov 7 2010, In : Bone marrow transplantation. 45, 11, p. 1658-1660 3 p.

Research output: Contribution to journalLetter

Transplantation Chimera
Hematopoietic Stem Cell Transplantation
Graft vs Host Disease
Drug Resistance
Steroids
2009

Utility of echocardiography in hypotension in the intensive care unit.

Verma, S., Kumar, S., Gossage, J. R. & Shah, V. B., Jan 1 2009, In : Hospital practice (1995). 37, 1, p. 64-70 7 p.

Research output: Contribution to journalArticle

Hypotension
Intensive Care Units
Echocardiography
Transesophageal Echocardiography
Left Ventricular Function
2008
4 Citations (Scopus)

Malignancy in kaolin pneumoconiosis found with F-18 FDG positron emission tomography

Williams, H. T., Solis, V., Dillard, T. A., Gossage, J. R. & Freant, L. J., Jan 1 2008, In : Clinical Nuclear Medicine. 33, 1, p. 4-7 4 p.

Research output: Contribution to journalArticle

Kaolin
Pneumoconiosis
Positron-Emission Tomography
Lung
Neoplasms
2007
15 Citations (Scopus)

Evaluation of patients with hereditary hemorrhagic telangiectasia with video capsule endoscopy: A single-center prospective study

Chamberlain, S. M., Patel, J., Carter Balart, J., Gossage, J. R. & Sridhar, S., Jun 1 2007, In : Endoscopy. 39, 6, p. 516-520 5 p.

Research output: Contribution to journalArticle

Capsule Endoscopy
Hereditary Hemorrhagic Telangiectasia
Prospective Studies
Telangiectasis
Hemorrhage
2005
4 Citations (Scopus)

Latex d-dimer signal in in situ femoral vein thrombus in swine and effect of minidose exogenous tissue plasminogen activator bolus

Robinson, V. J. B., Pineda, G. E., Salah, A. K., Pipkin, W. L., Corley, J. H., Jonah, M. H. & Gossage, J. R., Jan 1 2005, In : CHEST. 127, 2, p. 622-629 8 p.

Research output: Contribution to journalArticle

Femoral Vein
Latex
Tissue Plasminogen Activator
Thrombosis
Swine
2004
8 Citations (Scopus)

F-18 FDG positron emission tomography imaging of rare soft tissue sarcomas: Low-grade fibromyxoid sarcoma and malignant hemangiopericytoma

Williams, H. T., Gossage, J. R., Allred, T. J., Kallab, A. M., Pancholy, A. & Anstadt, M. P., Sep 1 2004, In : Clinical Nuclear Medicine. 29, 9, p. 581-584 4 p.

Research output: Contribution to journalArticle

Sarcoma
Positron-Emission Tomography
Neoplasm Metastasis
Glucose
Neoplasms
2003
25 Citations (Scopus)

The role of echocardiography in screening for pulmonary arteriovenous malformations

Gossage, J. R., Feb 1 2003, In : Chest. 123, 2, p. 320-322 3 p.

Research output: Contribution to journalEditorial

Arteriovenous Malformations
Echocardiography
Lung
2002
13 Citations (Scopus)
Triage
Pulmonary Embolism
Embolism
15 Citations (Scopus)

Optimal management of septic shock: Rapid recognition and institution of therapy are crucial

Fitch, S. J. & Gossage, J. R., Jan 1 2002, In : Postgraduate Medicine. 111, 3, p. 53-66 14 p.

Research output: Contribution to journalArticle

Septic Shock
Fluid Therapy
Immunocompromised Host
Immunosuppressive Agents
Microbial Drug Resistance
2000
38 Citations (Scopus)

Hemodynamic effects of epoprostenol in patients with systemic sclerosis and pulmonary hypertension

Strange, C., Bolster, M., Mazur, J., Taylor, M., Gossage, J. R. & Silver, R., Jan 1 2000, In : Chest. 118, 4, p. 1077-1082 6 p.

Research output: Contribution to journalArticle

Systemic Scleroderma
Epoprostenol
Pulmonary Hypertension
Hemodynamics
Interstitial Lung Diseases
1998
170 Citations (Scopus)

Massive pulmonary edema and death after prostacyclin infusion in a patient with pulmonary veno-occlusive disease

Palmer, S. M., Robinson, L. J., Wang, A., Gossage, J. R., Bashore, T. & Tapson, V. F., Jan 1 1998, In : Chest. 113, 1, p. 237-240 4 p.

Research output: Contribution to journalArticle

Pulmonary Veno-Occlusive Disease
Epoprostenol
Pulmonary Edema
Vasodilator Agents
Pulmonary Veins
1 Citation (Scopus)
Patent Foramen Ovale
Atrial Heart Septal Defects
Respiratory Function Tests
Sleep Apnea Syndromes
Obstructive Sleep Apnea
4 Citations (Scopus)

Primary pulmonary hypertension or portopulmonary hypertension? [2]

Gossage, J. R., Jan 1 1998, In : Chest. 114, 4, p. 1224-1225 2 p.

Research output: Contribution to journalArticle

Hypertension
Familial Primary Pulmonary Hypertension
404 Citations (Scopus)

Pulmonary arteriovenous malformations: A state of the art review

Gossage, J. R. & Kanj, G., Jan 1 1998, In : American Journal of Respiratory and Critical Care Medicine. 158, 2, p. 643-661 19 p.

Research output: Contribution to journalReview article

Therapeutic Embolization
Exercise Tolerance
Pulmonary Veins
Chromosome Mapping
Arteriovenous Malformations
1997

A 36-year-old woman with a chest mass and altered mental status

Garner, E. C. & Gossage, J. R., Jan 1 1997, In : Chest. 112, 3, p. 836-839 4 p.

Research output: Contribution to journalArticle

Thorax
1 Citation (Scopus)

Letter to the editor (multiple letters) [1]

Gossage, J. R., Lichtwarck-Aschoff, M., Beale, R. & Pfeiffer, U. J., Jan 1 1997, In : Journal of Critical Care. 12, 3, p. 152-153 2 p.

Research output: Contribution to journalArticle

Right Ventricular Function
Central Venous Pressure
Pulmonary Wedge Pressure
Physiologic Monitoring
Blood Volume
8 Citations (Scopus)

Of emperors, emboli, and echocardiography

Gossage, J. R., Jan 1 1997, In : Chest. 112, 5, p. 1158-1159 2 p.

Research output: Contribution to journalEditorial

Embolism
Echocardiography
1995
5 Citations (Scopus)

Gold pulmonary toxicity in a patient with a normal chest radiograph

Blackwell, T. S. & Gossage, J. R., Jan 1 1995, In : Southern Medical Journal. 88, 6, p. 644-646 3 p.

Research output: Contribution to journalArticle

Gold
Thorax
Adult-Onset Still's Disease
Lung
Dyspnea
7 Citations (Scopus)

Secretory leukoprotease inhibitor attenuates lung injury induced by continuous air embolization into sheep

Gossage, J. R., Perkett, E. A., Davidson, J. M., Starcher, B. C., Carmichael, D., Brigham, K. L. & Meyrick, B., Jan 1 1995, In : Journal of Applied Physiology. 79, 4, p. 1163-1172 10 p.

Research output: Contribution to journalArticle

Secretory Leukocyte Peptidase Inhibitor
Lung Injury
Sheep
Air
Pulmonary Hypertension
1994
2 Citations (Scopus)

Mediators of acute and chronic pulmonary hypertension: Part II

Gossage, J. R. & Christman, B. W., Jan 1 1994, In : Seminars in Respiratory and Critical Care Medicine. 15, 6, p. 453-462 10 p.

Research output: Contribution to journalReview article

Pulmonary Hypertension
3 Citations (Scopus)

Mediators of acute and chronic pulmonary hypertension (Part 1)

Gossage, J. R. & Christman, B. W., Jan 1 1994, In : Seminars in Respiratory and Critical Care Medicine. 15, 3, p. 190-198 9 p.

Research output: Contribution to journalReview article

Pulmonary Hypertension
1993
1 Citation (Scopus)

Elastin metabolism in the vessel wall during pulmonary hypertension

Davidson, J. M., Perkett, E. A., Gossage, J. R., Christman, J. W., Meyrick, B., Reeves, J., Laurent, G., Botney, M., Keeley, F., Gauldie, J. & Riley, D., Dec 1 1993, In : European Respiratory Review. 3, 16, p. 581-590 10 p.

Research output: Contribution to journalArticle

Elastin
Pulmonary Hypertension
Sheep
Lymph
Elastic Tissue

Lytic lament

Gossage, J. R., Oct 1 1993, In : The American Journal of Cardiology. 72, 11, 1 p.

Research output: Contribution to journalComment/debate

33 Citations (Scopus)

Neutrophil elastase inhibitors, SC-37698 and SC-39026, reduce endotoxin- induced lung dysfunction in awake sheep

Gossage, J. R., Kuratomi, Y., Davidson, J. M., Lefferts, P. L. & Snapper, J. R., Jan 1 1993, In : American Review of Respiratory Disease. 147, 6 I, p. 1371-1379 9 p.

Research output: Contribution to journalArticle

Secretory Proteinase Inhibitory Proteins
Endotoxins
Sheep
Lung
Endotoxemia
1992

Clinical trials: To terminate or not to terminate [4]

Gossage, J. R., Simberkoff, M. S., Hartigan, P. M., Hamilton, J. D., Laupacis, A., Connolly, S. J. & Gent, M., Jan 1 1992, In : Annals of Internal Medicine. 116, 8, p. 699-700 2 p.

Research output: Contribution to journalLetter

Informed Consent
Meta-Analysis
Clinical Trials