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Research Output 1987 2019

2019

A combined score of clinical factors and serum proteins can predict time to recurrence in high grade serous ovarian cancer

Mysona, D., Pyrzak, A., Purohit, S. B., Zhi, W., Sharma, A. K., Tran, L., Tran, P., Bai, S., Rungruang, B. J., Ghamande, S. A. & She, J-X., Mar 1 2019, In : Gynecologic Oncology. 152, 3, p. 574-580 7 p.

Research output: Contribution to journalArticle

Ovarian Neoplasms
Blood Proteins
Recurrence
Disease-Free Survival
Proteins

A pan-cancer perspective of matrix metalloproteases (MMP) gene expression profile and their diagnostic/prognostic potential

Gobin, E., Bagwell, K., Wagner, J., Mysona, D., Sandirasegarane, S., Smith, N., Bai, S., Sharma, A. K., Schleifer, R. & She, J-X., Jun 14 2019, In : BMC Cancer. 19, 1, 581.

Research output: Contribution to journalArticle

Open Access
Metalloproteases
Transcriptome
Matrix Metalloproteinases
Neoplasms
Genes

Genetic contribution to the divergence in type 1 diabetes risk between children from the general population and children from affected families

The TEDDY study group, Apr 1 2019, In : Diabetes. 68, 4, p. 847-857 11 p.

Research output: Contribution to journalArticle

Open Access
Type 1 Diabetes Mellitus
Population
Genetic Predisposition to Disease
Autoimmunity
Autoantibodies
1 Citation (Scopus)

Maternal dietary supplement use and development of islet autoimmunity in the offspring: TEDDY study

The TEDDY study group, Feb 1 2019, In : Pediatric Diabetes. 20, 1, p. 86-92 7 p.

Research output: Contribution to journalArticle

Dietary Supplements
Autoimmunity
Mothers
Autoantibodies
Vitamin D
1 Citation (Scopus)

Predicting islet cell autoimmunity and type 1 diabetes: An 8-year teddy study progress report

TEDDY study group, Jun 1 2019, In : Diabetes Care. 42, 6, p. 1051-1060 10 p.

Research output: Contribution to journalArticle

Autoimmunity
Type 1 Diabetes Mellitus
Islets of Langerhans
Autoantibodies
ROC Curve
1 Citation (Scopus)

Predicting progression to type 1 diabetes from ages 3 to 6 in islet autoantibody positive TEDDY children

The TEDDY study group, May 1 2019, In : Pediatric Diabetes. 20, 3, p. 263-270 8 p.

Research output: Contribution to journalArticle

Type 1 Diabetes Mellitus
Autoantibodies
Logistic Models
Insulinoma
Area Under Curve

Progression from islet autoimmunity to clinical type 1 diabetes is influenced by genetic factors: Results from the prospective TEDDY study

Beyerlein, A., Bonifacio, E., Vehik, K., Hippich, M., Winkler, C., Frohnert, B. I., Steck, A. K., Hagopian, W. A., Krischer, J. P., Lernmark, Å., Rewers, M. J., She, J-X., Toppari, J., Akolkar, B., Rich, S. S. & Ziegler, A. G., Sep 1 2019, In : Journal of medical genetics. 56, 9, p. 602-605 4 p.

Research output: Contribution to journalArticle

Autoimmunity
Type 1 Diabetes Mellitus
Autoantibodies
HLA Antigens
Genotype
2 Citations (Scopus)

Time-resolved autoantibody profiling facilitates stratification of preclinical type 1 diabetes in children

for the TEDDY Study Group*, Jan 1 2019, In : Diabetes. 68, 1, p. 119-130 12 p.

Research output: Contribution to journalArticle

Type 1 Diabetes Mellitus
Autoantibodies
Insulinoma
HLA-DR3 Antigen
Insulin
2018
11 Citations (Scopus)

Cesarean Section on the Risk of Celiac Disease in the Offspring: The Teddy Study

for the TEDDY Study Group, Mar 1 2018, In : Journal of Pediatric Gastroenterology and Nutrition. 66, 3, p. 417-424 8 p.

Research output: Contribution to journalArticle

Celiac Disease
Cesarean Section
Autoimmunity
Confidence Intervals
Nonparametric Statistics
1 Citation (Scopus)
Autoimmunity
Type 1 Diabetes Mellitus
Respiratory Tract Infections
Single Nucleotide Polymorphism
Emotions
2 Citations (Scopus)

Cytokeratin-8 in anaplastic thyroid carcinoma: More than a simple structural cytoskeletal protein

Guo, D., Xu, Q., Pabla, S., Koomen, J., Biddinger, P. W., Sharma, A. K., Pabla, S., Pacholczyk, R. W., Chang, C. C., Friedrich, K., Mohammed, K., Smallridge, R. C., Copland, J. A., She, J-X. & Weinberger, P. M., Feb 14 2018, In : International journal of molecular sciences. 19, 2, 577.

Research output: Contribution to journalArticle

Keratin-8
keratins
Keratin
Cytoskeletal Proteins
cancer
2 Citations (Scopus)

Diagnostic and prognostic biomarker potential of kallikrein family genes in different cancer types

Tailor, P. D., Kodeboyina, S. K., Bai, S., Sharma, S., Ratnani, A., Copland, J. A., She, J-X., Sharma, A. K. & Patel, N., Apr 1 2018, In : Oncotarget. 9, 25, p. 17876-17888 13 p.

Research output: Contribution to journalArticle

Kallikreins
Renal Cell Carcinoma
Biomarkers
Genes
Neoplasms
8 Citations (Scopus)

Early infant diet and islet autoimmunity in the TEDDY study

Uusitalo, U., Lee, H. S., Aronsson, C. A., Vehik, K., Yang, J., Hummel, S., Silvis, K., Lernmark, Å., Rewers, M., Hagopian, W., She, J-X., Simell, O., Toppari, J., Ziegler, A. G., Akolkar, B., Krischer, J., Virtanen, S. M. & Norris, J. M., Mar 1 2018, In : Diabetes Care. 41, 3, p. 522-530 9 p.

Research output: Contribution to journalArticle

Autoimmunity
Diet
Glutens
Type 1 Diabetes Mellitus
Insulin Antibodies
16 Citations (Scopus)

Genetic scores to stratify risk of developing multiple islet autoantibodies and type 1 diabetes: A prospective study in children

for the TEDDY Study Group, Apr 1 2018, In : PLoS Medicine. 15, 4, e1002548.

Research output: Contribution to journalArticle

Type 1 Diabetes Mellitus
Autoantibodies
Prospective Studies
Genotype
Primary Prevention
1 Citation (Scopus)
DNA Methylation
Methylation
Colorectal Neoplasms
Genome
Neoplasm Genes
5 Citations (Scopus)

Gestational respiratory infections interacting with offspring HLA and CTLA-4 modifies incident β-cell autoantibodies

TEDDY study group, Jan 1 2018, In : Journal of Autoimmunity. 86, p. 93-103 11 p.

Research output: Contribution to journalArticle

HLA Antigens
Respiratory Tract Infections
Autoantibodies
Type 1 Diabetes Mellitus
Infection
6 Citations (Scopus)

Identification of non-HLA genes associated with development of islet autoimmunity and type 1 diabetes in the prospective TEDDY cohort

TEDDY study group, May 1 2018, In : Journal of Autoimmunity. 89, p. 90-100 11 p.

Research output: Contribution to journalArticle

Autoimmunity
Type 1 Diabetes Mellitus
Genes
Single Nucleotide Polymorphism
Cohort Studies
1 Citation (Scopus)

Identification of novel macropinocytosis inhibitors using a rational screen of Food and Drug Administration-approved drugs

Lin, H. P., Singla, B., Ghoshal, P., Faulkner, J. L., Cherian-Shaw, M., O'Connor, P. M., She, J-X., Belin de Chantemele, E. J. & Csanyi, G., Sep 1 2018, In : British Journal of Pharmacology. 175, 18, p. 3640-3655 16 p.

Research output: Contribution to journalArticle

Imipramine
United States Food and Drug Administration
Pharmaceutical Preparations
Endocytosis
Electron Scanning Microscopy

KLHL5 knockdown increases cellular sensitivity to anticancer drugs

Schleifer, R. J., Li, S., Nechtman, W., Miller, E., Bai, S., Sharma, A. K. & She, J-X., Dec 1 2018, In : Oncotarget. 9, 100, p. 37429-37438 10 p.

Research output: Contribution to journalArticle

Pharmaceutical Preparations
Neoplasms
Cell Cycle
Aurora Kinases
Cullin Proteins
7 Citations (Scopus)

Multiplex glycan bead array for high throughput and high content analyses of glycan binding proteins

Purohit, S. B., Li, T., Guan, W., Song, X., Song, J., Tian, Y., Li, L., Sharma, A. K., Dun, B., Mysona, D., Ghamande, S. A., Rungruang, B. J., Cummings, R. D., Wang, P. G. & She, J-X., Dec 1 2018, In : Nature Communications. 9, 1, 258.

Research output: Contribution to journalArticle

antibodies
beads
Polysaccharides
Carrier Proteins
Throughput
2 Citations (Scopus)

Pandemrix® vaccination is not associated with increased risk of islet autoimmunity or type 1 diabetes in the TEDDY study children

for the TEDDY Study Group, Jan 1 2018, In : Diabetologia. 61, 1, p. 193-202 10 p.

Research output: Contribution to journalArticle

Autoimmunity
Type 1 Diabetes Mellitus
Vaccination
Autoantibodies
Finland
14 Citations (Scopus)

Plasma 25-Hydroxyvitamin D concentration and risk of islet autoimmunity

Norris, J. M., Lee, H. S., Frederiksen, B., Erlund, I., Uusitalo, U., Yang, J., Lernmark, Å., Simell, O., Toppari, J., Rewers, M., Ziegler, A. G., She, J-X., Onengut-Gumuscu, S., Chen, W. M., Rich, S. S., Sundvall, J., Akolkar, B., Krischer, J., Virtanen, S. M. & Hagopian, W., Jan 1 2018, In : Diabetes. 67, 1, p. 146-154 9 p.

Research output: Contribution to journalArticle

Autoimmunity
Type 1 Diabetes Mellitus
Vitamin D
25-Hydroxyvitamin D3 1-alpha-Hydroxylase
Odds Ratio

Proteins of TNF-α and IL6 pathways are elevated in serum of type-1 diabetes patients with microalbuminuria

Purohit, S. B., Sharma, A. K., Zhi, W., Bai, S., Hopkins, D., Steed, L., Bode, B., Anderson, S. W., Reed, J. C., Steed, R. D. & She, J-X., Jan 31 2018, In : Frontiers in immunology. 9, JAN, 154.

Research output: Contribution to journalArticle

Type 1 Diabetes Mellitus
Interleukin-6
Serum
Proteins
Cytokine Receptor gp130

Proteomic approach to identify biomarkers for invasive cervix cancer - a prospective pilot study

Mysona, D., Pyrzak, A., Allen, J., Powell, M., Kleven, D. T., Zhi, W., Sharma, A., Bai, S., She, J-X., Rungruang, B. J. & Ghamande, S. A., Jan 1 2018, In : European Journal of Gynaecological Oncology. 39, 5, p. 737-742 6 p.

Research output: Contribution to journalArticle

Uterine Cervical Neoplasms
Proteomics
Biomarkers
Prospective Studies
Serum
30 Citations (Scopus)

Temporal development of the gut microbiome in early childhood from the TEDDY study

Stewart, C. J., Ajami, N. J., O’Brien, J. L., Hutchinson, D. S., Smith, D. P., Wong, M. C., Ross, M. C., Lloyd, R. E., Doddapaneni, H. V., Metcalf, G. A., Muzny, D., Gibbs, R. A., Vatanen, T., Huttenhower, C., Xavier, R. J., Rewers, M., Hagopian, W., Toppari, J., Ziegler, A. G., She, J-X. & 6 others, Akolkar, B., Lernmark, A., Hyoty, H., Vehik, K., Krischer, J. P. & Petrosino, J. F., Oct 25 2018, In : Nature. 562, 7728, p. 583-588 6 p.

Research output: Contribution to journalLetter

Microbiota
Bacteroides
Human Milk
Autoimmunity
Type 1 Diabetes Mellitus
4 Citations (Scopus)

The Environmental Determinants of Diabetes in the Young (TEDDY) Study: 2018 Update

The TEDDY study group, Dec 1 2018, In : Current Diabetes Reports. 18, 12, 136.

Research output: Contribution to journalReview article

Type 1 Diabetes Mellitus
Autoimmunity
HLA-DQ Antigens
Gene-Environment Interaction
Micronutrients
41 Citations (Scopus)

The human gut microbiome in early-onset type 1 diabetes from the TEDDY study

Vatanen, T., Franzosa, E. A., Schwager, R., Tripathi, S., Arthur, T. D., Vehik, K., Lernmark, Å., Hagopian, W. A., Rewers, M. J., She, J-X., Toppari, J., Ziegler, A. G., Akolkar, B., Krischer, J. P., Stewart, C. J., Ajami, N. J., Petrosino, J. F., Gevers, D., Lähdesmäki, H., Vlamakis, H. & 2 others, Huttenhower, C. & Xavier, R. J., Oct 25 2018, In : Nature. 562, 7728, p. 589-594 6 p.

Research output: Contribution to journalLetter

Microbiota
Type 1 Diabetes Mellitus
Autoimmunity
Metagenome
Volatile Fatty Acids
2017
4 Citations (Scopus)

Analgesic antipyretic use among young children in the TEDDY study: No association with islet autoimmunity

for the TEDDY Study Group, May 16 2017, In : BMC pediatrics. 17, 1, 127.

Research output: Contribution to journalArticle

Antipyretics
Autoimmunity
Analgesics
Acetaminophen
Anti-Inflammatory Agents
11 Citations (Scopus)

Association between early-life antibiotic use and the risk of islet or celiac disease autoimmunity

Kemppainen, K. M., Vehik, K., Lynch, K. F., Larsson, H. E., Canepa, R. J., Simell, V., Koletzko, S., Liu, E., Simell, O. G., Toppari, J., Ziegler, A. G., Rewers, M. J., Lernmark, Å., Hagopian, W. A., She, J-X., Akolkar, B., Schatz, D. A., Atkinson, M. A., Blaser, M. J., Krischer, J. P. & 185 others, Hyöty, H., Agardh, D., Triplett, E. W., Bautista, K., Baxter, J., Bedoy, R., Felipe-Morales, D., Driscoll, K., Frohnert, B. I., Gesualdo, P., Hoffman, M., Karban, R., Norris, J., Samper-Imaz, A., Steck, A., Waugh, K., Wright, H., Adamsson, A., Ahonen, S., Ilonen, J., Jokipuu, S., Kallio, T., Karlsson, L., Kähönen, M., Knip, M., Kovanen, L., Koreasalo, M., Kurppa, K., Latva-Aho, T., Lönnrot, M., Mäntymäki, E., Multasuo, K., Mykkänen, J., Niininen, T., Niinistö, S., Nyblom, M., Rajala, P., Rautanen, J., Riikonen, A., Riikonen, M., Rouhiainen, J., Romo, M., Simell, T., Sjöberg, M., Stenius, A., Leppänen, M., Vainionpää, S., Varjonen, E., Veijola, R., Virtanen, S. M., Vähä-Mäkilä, M., Åkerlund, M., Lindfors, K., Schatz, D., Hopkins, D., Steed, L., Thomas, J., Adams, J., Silvis, K., Haller, M., Gardiner, M., McIndoe, R. A., Sharma, A. K., William, J., Young, G., Anderson, S. W., Jacobsen, L., Beyerlein, A., Bonifacio, E., Hummel, M., Hummel, S., Foterek, K., Janz, N., Kersting, M., Knopff, A., Peplow, C., Roth, R., Scholz, M., Stock, J., Warncke, K., Wendel, L., Winkler, C., Aronsson, C. A., Ask, M., Bremer, J., Carlsson, U. M., Cilio, C., Ericson-Hallström, E., Fransson, L., Gard, T., Gerardsson, J., Bennet, R., Hansen, M., Hansson, G., Hyberg, S., Johansen, F., Jonsdottir, B., Lindström, M., Lundgren, M., Månsson-Martinez, M., Markan, M., Melin, J., Mestan, Z., Ottosson, K., Rahmati, K., Ramelius, A., Salami, F., Sibthorpe, S., Sjöberg, B., Swartling, U., Amboh, E. T., Törn, C., Wallin, A., Wimar, Å., Åberg, S., Killian, M., Crouch, C. C., Skidmore, J., Carson, J., Dalzell, M., Dunson, K., Hervey, R., Johnson, C., Lyons, R., Meyer, A., Mulenga, D., Tarr, A., Uland, M., Willis, J., Becker, D., Franciscus, M., Smith, M. E. D. E., Daftary, A., Klein, M. B., Yates, C., Abbondondolo, M., Austin-Gonzalez, S., Avendano, M., Baethke, S., Brown, R., Burkhardt, B., Butterworth, M., Clasen, J., Cuthbertson, D., Eberhard, C., Fiske, S., Garcia, D., Garmeson, J., Gowda, V., Heyman, K., Laras, F. P., Lee, H. S., Liu, S., Liu, X., Lynch, K., Malloy, J., McCarthy, C., Meulemans, S., Parikh, H., Shaffer, C., Smith, L., Smith, S., Sulman, N., Tamura, R., Uusitalo, U., Vijayakandipan, P., Wood, K., Yang, J., Ballard, L., Hadley, D., McLeod, W., Bourcier, K., Briese, T., Johnson, S. B., Yu, L., Miao, D., Bingley, P., William's, A., Chandler, K., Rokni, S., Willia, C., Wyatt, R., George, G., Grace, S. & Mulholland, N., Dec 1 2017, In : JAMA Pediatrics. 171, 12, p. 1217-1225 9 p.

Research output: Contribution to journalArticle

Celiac Disease
Autoimmunity
Type 1 Diabetes Mellitus
Anti-Bacterial Agents
Autoantibodies
4 Citations (Scopus)

Blood-based biomarkers for precision medicine in lung cancer: Precision radiation therapy

De Ruysscher, D., Jin, J., Lautenschlaeger, T., She, J-X., Liao, Z. & Kong, F. M., Dec 1 2017, In : Translational Lung Cancer Research. 6, 6, p. 661-669 9 p.

Research output: Contribution to journalReview article

Precision Medicine
Lung Neoplasms
Radiotherapy
Biomarkers
Organs at Risk
12 Citations (Scopus)

Co-occurrence of type 1 diabetes and celiac disease autoimmunity

Hagopian, W., Lee, H. S., Liu, E., Rewers, M., She, J-X., Ziegler, A. G., Lernmark, A., Toppari, J., Rich, S. S., Krischer, J. P., Erlich, H., Akolkar, B. & Agardh, D., Nov 1 2017, In : Pediatrics. 140, 5, e20171305.

Research output: Contribution to journalArticle

Celiac Disease
Autoimmunity
Type 1 Diabetes Mellitus
Autoantibodies
Genetic Loci
31 Citations (Scopus)

Factors That Increase Risk of Celiac Disease Autoimmunity After a Gastrointestinal Infection in Early Life

TEDDY study group, May 1 2017, In : Clinical Gastroenterology and Hepatology. 15, 5, p. 694-702.e5

Research output: Contribution to journalArticle

Celiac Disease
Autoimmunity
Glutens
Infection
Rotavirus
11 Citations (Scopus)

First infant formula type and risk of islet autoimmunity in the environmental determinants of diabetes in the young (TEDDY) study

Hummel, S., Beyerlein, A., Tamura, R., Uusitalo, U., Andŕen Aronsson, C., Yang, J., Riikonen, A., Lernmark, A., Rewers, M. J., Hagopian, W. A., She, J-X., Simell, O. G., Toppari, J., Ziegler, A. G., Akolkar, B., Krischer, J. P., Virtanen, S. M. & Norris, J. M., Mar 1 2017, In : Diabetes Care. 40, 3, p. 398-404 7 p.

Research output: Contribution to journalArticle

Infant Formula
Autoimmunity
Type 1 Diabetes Mellitus
Survival Analysis
Breast Feeding
28 Citations (Scopus)

Genetic and environmental interactions modify the risk of diabetes-related autoimmunity by 6 years of age: The teddy study

Krischer, J. P., Lynch, K. F., Lernmark, A., Hagopian, W. A., Rewers, M. J., She, J-X., Toppari, J., Ziegler, A. G. & Akolkar, B., Sep 1 2017, In : Diabetes Care. 40, 9, p. 1194-1202 9 p.

Research output: Contribution to journalArticle

Autoimmunity
Autoantibodies
Single Nucleotide Polymorphism
Antibodies
Environmental Exposure
5 Citations (Scopus)

Identification of serum proteins and multivariate models for diagnosis and therapeutic monitoring of lung cancer

Ma, R., Xu, H., Wu, J., Sharma, A. K., Bai, S., Dun, B., Jing, C., Cao, H., Wang, Z., She, J-X. & Feng, J., Jan 1 2017, In : Oncotarget. 8, 12, p. 18901-18913 13 p.

Research output: Contribution to journalArticle

Blood Proteins
Lung Neoplasms
Non-Small Cell Lung Carcinoma
Proteins
Area Under Curve
8 Citations (Scopus)

Joint modeling of longitudinal autoantibody patterns and progression to type 1 diabetes: results from the TEDDY study

Ancillary Studies, Diet, Genetics, Human Subjects/Publicity/Publications, Immune Markers, Infectious Agents, Laboratory Implementation, Maternal Studies, Psychosocial, Quality Assurance, Steering, Study Coordinators, Celiac Disease, Clinical Implementation & TEDDY study group, Nov 1 2017, In : Acta Diabetologica. 54, 11, p. 1009-1017 9 p.

Research output: Contribution to journalArticle

Type 1 Diabetes Mellitus
Autoantibodies
Joints
Bayes Theorem
Statistical Models
5 Citations (Scopus)

Maternal use of dietary supplements during pregnancy is not associated with coeliac disease in the offspring: The Environmental Determinants of Diabetes in the Young (TEDDY) study

Yang, J., Tamura, R. N., Aronsson, C. A., Uusitalo, U. M., Lernmark, Å., Rewers, M., Hagopian, W. A., She, J-X., Toppari, J., Ziegler, A. G., Akolkar, B., Krischer, J. P., Norris, J. M., Virtanen, S. M. & Agardh, D., Feb 14 2017, In : British Journal of Nutrition. 117, 3, p. 466-472 7 p.

Research output: Contribution to journalArticle

Celiac Disease
Dietary Supplements
Mothers
Pregnancy
Autoimmunity
12 Citations (Scopus)

Psychological manifestations of celiac disease autoimmunity in young children

The TEDDY study group, Mar 1 2017, In : Pediatrics. 139, 3, e20162848.

Research output: Contribution to journalArticle

Celiac Disease
Autoimmunity
Psychology
Mothers
Autoantibodies
19 Citations (Scopus)

Respiratory infections are temporally associated with initiation of type 1 diabetes autoimmunity: the TEDDY study

On behalf of the TEDDY Study Group, Oct 1 2017, In : Diabetologia. 60, 10, p. 1931-1940 10 p.

Research output: Contribution to journalArticle

Autoimmunity
Type 1 Diabetes Mellitus
Respiratory Tract Infections
Autoantibodies
Tracheitis
26 Citations (Scopus)

The influence of type 1 diabetes genetic susceptibility regions, age, sex, and family history on the progression from multiple autoantibodies to type 1 diabetes: A teddy study report

Krischer, J. P., Liu, X., Lernmark, Å., Hagopian, W. A., Rewers, M. J., She, J-X., Toppari, J., Ziegler, A. G. & Akolkar, B., Dec 1 2017, In : Diabetes. 66, 12, p. 3122-3129 8 p.

Research output: Contribution to journalArticle

Genetic Predisposition to Disease
Type 1 Diabetes Mellitus
Autoantibodies
HLA-DQ Antigens
HLA-DR Antigens
2016
6 Citations (Scopus)
Regression Analysis
Pediatrics
Logistic Models
Population
Health
81 Citations (Scopus)

Association of Early Exposure of Probiotics and Islet Autoimmunity in the TEDDY Study

Dietary Biomarkers Laboratory, Project Scientist, Other contributors, Autoantibody Reference Laboratories, Cortisol Laboratory, Data Coordinating Center, Pennsylvania Satellite Center, Washington Clinical Center, Sweden Clinical Center, Finland Clinical Center, Germany Clinical Center, Georgia/Florida Clinical Center, for the TEDDY Study Group, SNP Laboratory, RNA Laboratory and Gene Expression Laboratory, Microbiome and Viral Metagenomics Laboratory, Metabolomics Laboratory, HbA1c Laboratory, HLA Reference Laboratory, OGTT Laboratory & 2 others, Proteomics Laboratory & Repository, Jan 1 2016, In : JAMA Pediatrics. 170, 1, p. 20-28 9 p.

Research output: Contribution to journalArticle

Probiotics
Autoimmunity
Type 1 Diabetes Mellitus
Genotype
Autoantibodies
9 Citations (Scopus)

Characterization of immune response to novel HLA-A2-restricted epitopes from zinc transporter 8 in type 1 diabetes

Xu, X., Gu, Y., Bian, L., Shi, Y., Cai, Y., Chen, Y., Chen, H., Qian, L., Wu, X., Xu, K., Mallone, R., Davidson, H. W., Yu, L., She, J-X., Zhang, M. & Yang, T., Feb 3 2016, In : Vaccine. 34, 6, p. 854-862 9 p.

Research output: Contribution to journalArticle

HLA-A2 Antigen
insulin-dependent diabetes mellitus
Type 1 Diabetes Mellitus
epitopes
transporters
11 Citations (Scopus)

Complement gene variants in relation to autoantibodies to beta cell specific antigens and type 1 diabetes in the TEDDY Study

Törn, C., Liu, X., Hagopian, W., Lernmark, Å., Simell, O., Rewers, M., Ziegler, A. G., Schatz, D., Akolkar, B., Onengut-Gumuscu, S., Chen, W. M., Toppari, J., Mykkänen, J., Ilonen, J., Rich, S. S., She, J-X., Sharma, A. K., Steck, A. & Krischer, J., Jun 16 2016, In : Scientific Reports. 6, 27887.

Research output: Contribution to journalArticle

Type 1 Diabetes Mellitus
Autoantibodies
Single Nucleotide Polymorphism
Antigens
Genes
26 Citations (Scopus)

Co-targeting EGFR and survivin with a bivalent aptamer-dual siRNA chimera effectively suppresses prostate cancer

Liu, H., Yu, X., Liu, H., Wu, D. & She, J-X., Jul 26 2016, In : Scientific Reports. 6, 30346.

Research output: Contribution to journalArticle

Small Interfering RNA
Prostatic Neoplasms
Nucleotide Aptamers
Antibodies
Heterografts
2 Citations (Scopus)

Factors associated with longitudinal food record compliance in a paediatric cohort study

Yang, J., Lynch, K. F., Uusitalo, U. M., Foterek, K., Hummel, S., Silvis, K., Andrén Aronsson, C., Riikonen, A., Rewers, M., She, J-X., Ziegler, A. G., Simell, O. G., Toppari, J., Hagopian, W. A., Lernmark, Å., Akolkar, B., Krischer, J. P., Norris, J. M., Virtanen, S. M. & Johnson, S. B., Apr 1 2016, In : Public Health Nutrition. 19, 5, p. 804-813 10 p.

Research output: Contribution to journalArticle

Compliance
Cohort Studies
Pediatrics
Food
Ambulatory Care
9 Citations (Scopus)

Growth and risk for islet autoimmunity and progression to type 1 diabetes in early childhood: The environmental determinants of diabetes in the young study

Larsson, H. E., Vehik, K., Haller, M. J., Liu, X., Akolkar, B., Hagopian, W., Krischer, J., Lernmark, Å., She, J-X., Simell, O., Toppari, J., Ziegler, A. G. & Rewers, M., Jul 1 2016, In : Diabetes. 65, 7, p. 1988-1995 8 p.

Research output: Contribution to journalArticle

Autoimmunity
Type 1 Diabetes Mellitus
Weights and Measures
Growth
Body Size
15 Citations (Scopus)

Identification of Non-HLA Genes Associated with Celiac Disease and Country-Specific Differences in a Large, International Pediatric Cohort

TEDDY study group, Jan 1 2016, In : PloS one. 11, 3, p. e0152476

Research output: Contribution to journalArticle

Pediatrics
celiac disease
Celiac Disease
Genes
autoantibodies
4 Citations (Scopus)

IGF-binding proteins in type-1 diabetes are more severely altered in the presence of complications

Sharma, A. K., Purohit, S. B., Sharma, S., Bai, S., Zhi, W., Ponny, S. R., Hopkins, D., Steed, L., Bode, B., Anderson, S. W. & She, J-X., Jan 1 2016, In : Frontiers in Endocrinology. 7, JAN, 2.

Research output: Contribution to journalArticle

Insulin-Like Growth Factor Binding Protein 1
Type 1 Diabetes Mellitus
Diabetes Complications
Insulin-Like Growth Factor Binding Proteins
Insulin-Like Growth Factor Binding Protein 2
15 Citations (Scopus)

Reversion of β-cell autoimmunity changes risk of type 1 diabetes: TEDDY study

Vehik, K., Lynch, K. F., Schatz, D. A., Akolkar, B., Hagopian, W., Rewers, M., She, J-X., Simell, O., Toppari, J., Ziegle, A. G., Lernmark, A., Bonifacio, E. & Krischer, J. P., Sep 1 2016, In : Diabetes Care. 39, 9, p. 1535-1542 8 p.

Research output: Contribution to journalArticle

Autoimmunity
Type 1 Diabetes Mellitus
Autoantibodies
Insulin
Insulinoma