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Research Output

Cellular immune responses to β casein: Elevated in but not specific for individuals with Type I diabetes mellitus

Ellis, T. M., Ottendorfer, E., Jodoin, E., Salisbury, P. J., She, J. X., Schatz, D. A. & Atkinson, M. A., Jun 18 1998, In : Diabetologia. 41, 6, p. 731-735 5 p.

Research output: Contribution to journalArticle

28 Scopus citations

Central (ICV) leptin injection increases bone formation, bone mineral density, muscle mass, serum IGF-1, and the expression of osteogenic genes in leptin-deficient ob/ob mice

Bartell, S. M., Rayalam, S., Ambati, S., Gaddam, D. R., Hartzell, D. L., Hamrick, M. W., She, J-X., Della-Fera, M. A. & Baile, C. A., Aug 1 2011, In : Journal of Bone and Mineral Research. 26, 8, p. 1710-1720 11 p.

Research output: Contribution to journalArticle

102 Scopus citations

Cesarean Section on the Risk of Celiac Disease in the Offspring: The Teddy Study

for the TEDDY Study Group, Mar 1 2018, In : Journal of Pediatric Gastroenterology and Nutrition. 66, 3, p. 417-424 8 p.

Research output: Contribution to journalArticle

14 Scopus citations

Characterization of immune response to novel HLA-A2-restricted epitopes from zinc transporter 8 in type 1 diabetes

Xu, X., Gu, Y., Bian, L., Shi, Y., Cai, Y., Chen, Y., Chen, H., Qian, L., Wu, X., Xu, K., Mallone, R., Davidson, H. W., Yu, L., She, J-X., Zhang, M. & Yang, T., Feb 3 2016, In : Vaccine. 34, 6, p. 854-862 9 p.

Research output: Contribution to journalArticle

14 Scopus citations

Characterization of mutations in patients with autoimmune polyglandular syndrome type 1 (APS1)

Wang, C. Y., Davoodi-Semiromi, A., Huang, W., Connor, E., Shi, J. D. & She, J-X., Dec 1 1998, In : Human Genetics. 103, 6, p. 681-685 5 p.

Research output: Contribution to journalArticle

114 Scopus citations

Characterization of PAF-AH Ib1 in NOD mice: PAF-AH may not be a candidate gene of the diabetes susceptibility Idd4.1 locus

Mi, Q. S., Zhou, L., Grattan, M., Wang, Z. Z., Sivilotti, M., She, J-X. & Delovitch, T. L., Oct 2006, Immunology of Diabetes IV: Progress in Our Understanding. Blackwell Publishing Inc., p. 147-152 6 p. (Annals of the New York Academy of Sciences; vol. 1079).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Characterizations of candidate genes for IDD susceptibility from the diabetes-prone NOD mouse strain

Chesnut, K., She, J. X., Cheng, I., Muralidharan, K. & Wakeland, E. K., Oct 1 1993, In : Mammalian Genome. 4, 10, p. 549-554 6 p.

Research output: Contribution to journalArticle

27 Scopus citations

Chemokine (c-c motif) ligand 2 (ccl2) in sera of patients with type 1 diabetes and diabetic complications

Guan, R., Purohit, S. B., Wang, H., Bode, B., Reed, J. C., Steed, R. D., Anderson, S. W., Steed, L., Hopkins, D., Xia, C. & She, J-X., 2011, In : PloS one. 6, 4, e17822.

Research output: Contribution to journalArticle

19 Scopus citations

Children followed in the TEDDY study are diagnosed with type 1 diabetes at an early stage of disease

Elding Larsson, H., Vehik, K., Gesualdo, P., Akolkar, B., Hagopian, W., Krischer, J., Lernmark, Å., Rewers, M., Simell, O., She, J. X., Ziegler, A. & Haller, M. J., Mar 2014, In : Pediatric Diabetes. 15, 2, p. 118-126 9 p.

Research output: Contribution to journalArticle

39 Scopus citations

Chromosomal localization and complete genomic sequence of the murine autoimmune regulator gene (Aire)

Shi, J. D., Wang, C. Y., Marron, M. P., Ruan, Q. G., Huang, Y. Q., Detter, J. C. & She, J-X., Jan 1 1999, In : Autoimmunity. 31, 1, p. 47-53 7 p.

Research output: Contribution to journalArticle

5 Scopus citations

Chronic inflammatory demyelinating polyradiculoneuropathy in two children with type 1 diabetes mellitus

Fudge, E., Carol, J., She, J. X., Dosch, M., Atkinson, M. & Muir, A., Dec 1 2005, In : Pediatric Diabetes. 6, 4, p. 244-248 5 p.

Research output: Contribution to journalArticle

8 Scopus citations

Clinical calculator predictive of chemotherapy benefit in stage 1A uterine papillary serous cancers

Mysona, D. P., Tran, L. K. H., Tran, P. M. H., Gehrig, P. A., Van Le, L., Ghamande, S., Rungruang, B. J., Java, J., Mann, A. K., Liao, J., Kapp, D. S., Santos, B. D., She, J. X. & Chan, J. K., Jan 2020, In : Gynecologic Oncology. 156, 1, p. 77-84 8 p.

Research output: Contribution to journalArticle

2 Scopus citations

Cloning of Aire, the mouse homologue of the autoimmune regulator (AIRE) gene responsible for autoimmune polyglandular syndrome Type 1 (APS1)

Wang, C. Y., Shi, J. D., Davoodi-Semiromi, A. & She, J. X., Feb 1 1999, In : Genomics. 55, 3, p. 322-326 5 p.

Research output: Contribution to journalArticle

38 Scopus citations

Combinations of HLA DR and DQ molecules determine the susceptibility to insulin-dependent diabetes mellitus in Koreans

Park, Y. S., Wang, C. Y., Ko, K. W., Yang, S. W., Park, M., Yang, M. C. K. & She, J. X., Dec 1 1998, In : Human Immunology. 59, 12, p. 794-801 8 p.

Research output: Contribution to journalArticle

49 Scopus citations
1 Scopus citations

Common susceptibility and transmission pattern of human leukocyte antigen DRB1-DQB1 haplotypes to Korean and Caucasian patients with type 1 diabetes

Park, Y., She, J. X., Wang, C. Y., Lee, H., Babu, S., Erlich, H. A., Noble, J. A. & Eisenbarth, G. S., Dec 1 2000, In : Journal of Clinical Endocrinology and Metabolism. 85, 12, p. 4538-4542 5 p.

Research output: Contribution to journalArticle

25 Scopus citations

Complement gene variants in relation to autoantibodies to beta cell specific antigens and type 1 diabetes in the TEDDY Study

Törn, C., Liu, X., Hagopian, W., Lernmark, Å., Simell, O., Rewers, M., Ziegler, A. G., Schatz, D., Akolkar, B., Onengut-Gumuscu, S., Chen, W. M., Toppari, J., Mykkänen, J., Ilonen, J., Rich, S. S., She, J-X., Sharma, A. K., Steck, A. & Krischer, J., Jun 16 2016, In : Scientific reports. 6, 27887.

Research output: Contribution to journalArticle

16 Scopus citations

Confirmation of novel type 1 diabetes risk loci in families

Cooper, J. D., Howson, J. M. M., Smyth, D., Walker, N. M., Stevens, H., Yang, J. H. M., She, J. X., Eisenbarth, G. S., Rewers, M., Todd, J. A., Akolkar, B., Concannon, P., Erlich, H. A., Julier, C., Morahan, G., Nerup, J., Nierras, C., Pociot, F. & Rich, S. S., Apr 2012, In : Diabetologia. 55, 4, p. 996-1000 5 p.

Research output: Contribution to journalArticle

31 Scopus citations

Confirmation of three susceptibility genes to insulin-dependent diabetes mellitus: IDDM4, IDDM5 and IDDM8

Luo, D. F., Buzzetti, R., Rotter, J. I., Maclaren, N. K., Raffel, L. J., Nisticò, L., Giovannini, C., Pozzilli, P., Thomson, G. & She, J-X., May 1996, In : Human Molecular Genetics. 5, 5, p. 693-698 6 p.

Research output: Contribution to journalArticle

134 Scopus citations

Construction of a physical and transcript map for a 1-Mb genomic region containing the urofacial (Ochoa) syndrome gene on 10q23-q24 and localization of the disease gene within two overlapping BAC clones (<360 kb)

Wang, C. Y., Shi, J. D., Huang, Y. Q., Cruz, P. E., Ochoa, B., Hawkins-Lee, B., Davoodi-Semiromi, A. & She, J. X., Aug 15 1999, In : Genomics. 60, 1, p. 12-19 8 p.

Research output: Contribution to journalArticle

18 Scopus citations

Co-occurrence of type 1 diabetes and celiac disease autoimmunity

Hagopian, W., Lee, H. S., Liu, E., Rewers, M., She, J. X., Ziegler, A. G., Lernmark, A., Toppari, J., Rich, S. S., Krischer, J. P., Erlich, H., Akolkar, B. & Agardh, D., Nov 2017, In : Pediatrics. 140, 5, e20171305.

Research output: Contribution to journalArticle

25 Scopus citations
1 Scopus citations

Co-targeting EGFR and survivin with a bivalent aptamer-dual siRNA chimera effectively suppresses prostate cancer

Liu, H., Yu, X., Liu, H., Wu, D. & She, J-X., Jul 26 2016, In : Scientific reports. 6, 30346.

Research output: Contribution to journalArticle

31 Scopus citations

Country-specific birth weight and length in type 1 diabetes high-risk HLA genotypes in combination with prenatal characteristics

Sterner, Y., Törn, C., Lee, H. S., Larsson, H., Winkler, C., McLeod, W., Lynch, K., Simell, O., Ziegler, A., Schatz, D., Hagopian, W., Rewers, M., She, J. X., Krischer, J. P., Akolkar, B. & Lernmark, Å., Dec 2011, In : Journal of Perinatology. 31, 12, p. 764-769 6 p.

Research output: Contribution to journalArticle

6 Scopus citations

Cytokeratin-8 in anaplastic thyroid carcinoma: More than a simple structural cytoskeletal protein

Guo, D., Xu, Q., Pabla, S., Koomen, J., Biddinger, P. W., Sharma, A. K., Pabla, S., Pacholczyk, R. W., Chang, C. C., Friedrich, K., Mohammed, K., Smallridge, R. C., Copland, J. A., She, J-X. & Weinberger, P. M., Feb 14 2018, In : International journal of molecular sciences. 19, 2, 577.

Research output: Contribution to journalArticle

2 Scopus citations

Delineating the angiogenic gene expression profile before pulmonary vascular remodeling in a lamb model of congenital heart disease

Tian, J., Fratz, S., Hou, Y., Lu, Q., Görlach, A., Hess, J., Schreiber, C., Datar, S. A., Oishi, P., Nechtman, J., Podolsky, R., She, J. X., Fineman, J. R. & Black, S. M., Jan 2011, In : Physiological Genomics. 43, 2, p. 87-98 12 p.

Research output: Contribution to journalArticle

11 Scopus citations

Delineation of biological and molecular mechanisms underlying the diverse anticancer activities of mycophenolic acid

Dun, B., Xu, H., Sharma, A. K., Liu, H., Yu, H., Yi, B., Liu, X., He, M., Zeng, L. & She, J-X., Dec 5 2013, In : International Journal of Clinical and Experimental Pathology. 6, 12, p. 2880-2886 7 p.

Research output: Contribution to journalArticle

13 Scopus citations

Delineation of gastric cancer subtypes by co-regulated expression of receptor tyrosine kinases and chemosensitivity genes

Li, S. C., Ma, R., Wu, J. Z., Xiao, X., Wu, W., Li, G., Chen, B., Sharma, A. K., Bai, S., Dun, B. Y., She, J-X. & Tang, J. H., Sep 11 2015, In : American Journal of Translational Research. 7, 8, p. 1429-1439 11 p.

Research output: Contribution to journalArticle

8 Scopus citations

Depressive symptoms in mothers of infants identified as genetically at risk for type 1 diabetes

Hood, K. K., Johnson, S. B., Carmichael, S. K., Laffel, L. M. B., She, J-X. & Schatz, D. A., Aug 1 2005, In : Diabetes Care. 28, 8, p. 1898-1903 6 p.

Research output: Contribution to journalArticle

15 Scopus citations

Derivatives containing both coumarin and benzimidazole potently induce caspase-dependent apoptosis of cancer cells through inhibition of PI3K-AKT-mTOR signaling

Liu, H., Wang, Y., Sharma, A. K., Mao, R., Jiang, N., Dun, B. & She, J-X., Jun 9 2015, In : Anti-Cancer Drugs. 26, 6, p. 667-677 11 p.

Research output: Contribution to journalArticle

11 Scopus citations

Design, Synthesis, and in Vitro Evaluation of Novel 3, 7-Disubstituted Coumarin Derivatives as Potent Anticancer Agents

Wang, Y., Liu, H., Lu, P., Mao, R., Xue, X., Fan, C. & She, J., Oct 1 2015, In : Chemical Biology and Drug Design. 86, 4, p. 637-647 11 p.

Research output: Contribution to journalArticle

10 Scopus citations
13 Scopus citations

Detection of AIRE mutation in atypical autoimmune polyglandular syndrome type 1 (APS1)

Guttmann-Bauman, I., Shi, J. D., Wang, C. Y., She, J. X. & Guttmann-Bauman, I., Aug 23 2001, In : Journal of Endocrine Genetics. 2, 2, p. 115-121 7 p.

Research output: Contribution to journalArticle

1 Scopus citations

Detection of lactobacilli in monthly mail-in stool samples from 3-18 months old infants at genetic risk for type 1 diabetes

Salami, F., Abels, M., Hyöty, H., Vaziri-Sani, F., Aronsson, C. A., Vehik, K., Delli, A., Hagopian, W. A., Rewers, M., Ziegler, A. G., Simell, O., Akolkar, B., Krischer, J., She, J. & Leramark, Å., Dec 1 2012, In : International Journal of Probiotics and Prebiotics. 7, 3-4, p. 135-144 10 p.

Research output: Contribution to journalArticle

4 Scopus citations

Developments in small molecule immunosuppressive drugs

Liu, Y., Wang, Y. B., Zhang, Q. & She, J-X., Oct 30 2011, In : Chinese Journal of New Drugs. 20, 20, p. 1981-1988 8 p.

Research output: Contribution to journalReview article

Diagnostic and prognostic biomarker potential of kallikrein family genes in different cancer types

Tailor, P. D., Kodeboyina, S. K., Bai, S., Sharma, S., Ratnani, A., Copland, J. A., She, J-X., Sharma, A. K. & Patel, N., Apr 1 2018, In : Oncotarget. 9, 25, p. 17876-17888 13 p.

Research output: Contribution to journalArticle

10 Scopus citations

Dietary intake of soluble fiber and risk of islet autoimmunity by 5 y of age: Results from the TEDDY study

Beyerlein, A., Liu, X., Uusitalo, U. M., Harsunen, M., Norris, J. M., Foterek, K., Virtanen, S. M., Rewers, M. J., She, J. X., Simell, O., Lernmark, A., Hagopian, W., Akolkar, B., Ziegler, A. G., Krischer, J. P. & Hummel, S., Aug 1 2015, In : American Journal of Clinical Nutrition. 102, 2, p. 345-352 8 p.

Research output: Contribution to journalArticle

12 Scopus citations

Differences in recruitment and early retention among ethnic minority participants in a large pediatric cohort: The TEDDY Study

Baxter, J., Vehik, K., Johnson, S. B., Lernmark, B., Roth, R., Simell, T., Rewers, M., Barriga, K., Bautista, K., Baxter, J., Eisenbarth, G., Frank, N., Gesualdo, P., Hoffman, M., Ide, L., Karban, R., Liu, E., Norris, J., Waugh, K., Samper-Imaz, A. & 149 others, Steck, A., She, J-X., Schatz, D., Hopkins, D., Steed, L., Thomas, J., Silvis, K., Haller, M., Shankar, M., English, K., McIndoe, R. A., Liu, H., Nechtman, J., Williams, J., Foghis, G., Stephen, W., Anderson, M. D., Ziegler, A. G., Achenbach, A., Boerschmann, H., Bonifacio, E., Bunk, M., Försch, J., Henneberger, L., Hummel, M., Hummel, S., Joslowski, G., Kersting, M., Knopff, A., Kocher, N., Koletzko, S., Krause, S., Mann, A., Matzke, C., Mittermeier, A., Peplow, C., Pflüger, M., Ramminger, C., Strauss, E., Rash-Sur, S., Roth, R., Schenkel, J., Stock, J., Voit, K., Winkler, C., Wosch, A., Zwilling, M., Simell, O. G., Nanto-Salonen, K., Ilonen, J., Knip, M., Tuula Simell, V., Hyöty, H., Virtanen, S. M., Kronberg-Kippilä, C., Sjöberg, M., Simell, B., Ruohonen, E., Romo, M., Mantymaki, E., Schroderus, H., Nyblom, M., Stenius, A., Lernmark, Å., Agardh, D., Almgren, P., Andersson, E., Andrén-Aronsson, C., Ask, M., Karlsson, U. M., Cilio, C., Bremer, J., Ericson-Hallström, E., Gard, T., Gerardsson, J., Hansson, G., Hansen, M., Hyberg, S., Håkansson, R., Johansen, F., Jonsson, L., Larsson, H., Lernmark, B., Markan, M., Massadakis, T., Melin, J., Månsson-Martinez, M., Nilsson, A., Rahmati, K., Järvirova, M. S., Sibthorpe, S., Sjöberg, B., Skogberg, A., Törn, C., Wallin, A., Wimar, Å., Åberg, S., Hagopian, W. A., Yan, X., Killian, M., Cowen Crouch, C., Hay, K. M., Ayres, S., Adams, C., Bratrude, B., Coughlin, D., Fowler, G., Franco, C., Hammar, C., Heaney, D., Marcus, P., Meyer, A., Mulenga, D., Scott, E., Skidmore, J., Stabbert, J., Stepitova, V., Williams, N., Becker, D., Franciscus, M., Dalmagro-Elias, M. E., Daftary, A., Krischer, J. P., Abbondondolo, M., Ballard, L., Brown, R., Burkhardt, B., Cuthbertson, D., Eberhard, C., Fiske, S., Gowda, V., Hadley, D., Lee, H. S., Liu, S., Lynch, K., Malloy, J., McCarthy, C., McLeod, W., Smith, L., Smith, S., Uusitalo, U., Vehik, K., Washington, E., Yang, J., Akolkar, B., Briese, T., Erlich, H., Johnson, S. B. & Oberste, S., Jul 2012, In : Contemporary Clinical Trials. 33, 4, p. 633-640 8 p.

Research output: Contribution to journalArticle

25 Scopus citations
28 Scopus citations
26 Scopus citations

Discovery and validation of serum protein changes in type 1 diabetes patients using high throughput two dimensional liquid chromatography-mass spectrometry and immunoassays.

Zhi, W., Sharma, A., Purohit, S., Miller, E., Bode, B., Anderson, S. W., Reed, J. C., Steed, R. D., Steed, L., Hopkins, D. & She, J. X., Nov 1 2011, In : Molecular & cellular proteomics : MCP. 10, 11

Research output: Contribution to journalArticle

41 Scopus citations

Disordered osteoclast formation in RAGE-deficient mouse establishes an essential role for RAGE in diabetes related bone loss

Ding, K., Wang, Z. Z., Hamrick, M. W., Deng, Z. B., Zhou, L., Kang, B., Yan, S. L., She, J-X., Stern, D. M., Isales, C. M. & Mi, Q. S., Feb 24 2006, In : Biochemical and Biophysical Research Communications. 340, 4, p. 1091-1097 7 p.

Research output: Contribution to journalArticle

88 Scopus citations

Distinct growth phases in early life associated with the risk of type 1 diabetes: The teddy study

TEDDY study group, Mar 1 2020, In : Diabetes Care. 43, 3, p. 556-562 7 p.

Research output: Contribution to journalArticle

Early childhood gut microbiomes show strong geographic differences among subjects at high risk for type 1 diabetes

Kemppainen, K. M., Ardissone, A. N., Davis-Richardson, A. G., Fagen, J. R., Gano, K. A., León-Novelo, L. G., Vehik, K., Casella, G., Simell, O., Ziegler, A. G., Rewers, M. J., Lernmark, Å., Hagopian, W., She, J. X., Krischer, J. P., Akolkar, B., Schatz, D. A., Atkinson, M. A. & Triplett, E. W., Feb 1 2015, In : Diabetes Care. 38, 2, p. 329-332 4 p.

Research output: Contribution to journalArticle

47 Scopus citations

Early Diagnosis and Specific Treatment of Insulin‐Dependent Diabetes

MACLAREN, NOEL., MUIR, ANDREW., SILVERSTEIN, JANET., SONG, YAOHUA. H., SHE, JIN. XIONG., KRISCHER, JEFFREY., ATKINSON, MARK. & SCHATZ, DESMOND., Jan 1 1993, In : Annals of the New York Academy of Sciences. 696, 1, p. 342-350 9 p.

Research output: Contribution to journalArticle

Early infant diet and islet autoimmunity in the TEDDY study

Uusitalo, U., Lee, H. S., Aronsson, C. A., Vehik, K., Yang, J., Hummel, S., Silvis, K., Lernmark, Å., Rewers, M., Hagopian, W., She, J. X., Simell, O., Toppari, J., Ziegler, A. G., Akolkar, B., Krischer, J., Virtanen, S. M. & Norris, J. M., Mar 1 2018, In : Diabetes Care. 41, 3, p. 522-530 9 p.

Research output: Contribution to journalArticle

23 Scopus citations

Early pathogenic events associated with Sjögren's syndrome (SjS)-like disease of the nod mouse using microarray analysis

Killedar, S. Y., Eckenrode, S. E., McIndoe, R. A., She, J. X., Nguyen, C. Q., Peck, A. B. & Cha, S. R., Dec 2 2006, In : Laboratory Investigation. 86, 12, p. 1243-1260 18 p.

Research output: Contribution to journalArticle

46 Scopus citations

Early probiotic supplementation and the risk of celiac disease in children at genetic risk

TEDDY study group, Aug 2019, In : Nutrients. 11, 8, 1790.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Effect of PPARγ inhibition on pulmonary endothelial cell gene expression: Gene profiling in pulmonary hypertension

Tian, J., Smith, A., Nechtman, J., Podolsky, R., Aggarwal, S., Snead, C., Kumar, S., Elgaish, M., Oishi, P., Göerlach, A., Fratz, S., Hess, J., Catravas, J. D., Verin, A. D., Fineman, J. R., She, J. X. & Black, S. M., Jan 2009, In : Physiological Genomics. 40, 1, p. 48-60 13 p.

Research output: Contribution to journalArticle

35 Scopus citations
17 Scopus citations