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Research Output

Identification of novel macropinocytosis inhibitors using a rational screen of Food and Drug Administration-approved drugs

Lin, H. P., Singla, B., Ghoshal, P., Faulkner, J. L., Cherian-Shaw, M., O'Connor, P. M., She, J. X., Belin de Chantemele, E. J. & Csányi, G., Sep 2018, In : British Journal of Pharmacology. 175, 18, p. 3640-3655 16 p.

Research output: Contribution to journalArticle

12 Scopus citations

Identification of novel T1D risk loci and their association with age and islet function at diagnosis in autoantibody-positive T1D individuals: Based on a two-stage genome-wide association study

Zhu, M., Xu, K., Chen, Y., Gu, Y., Zhang, M., Luo, F., Liu, Y., Gu, W., Hu, J., Xu, H., Xie, Z., Sun, C., Li, Y., Sun, M., Xu, X., Hsu, H. T., Chen, H., Fu, Q., Shi, Y., Xu, J. & 33 others, Ji, L., Liu, J., Bian, L., Zhu, J., Chen, S., Xiao, L., Li, X., Jiang, H., Shen, M., Huang, Q., Fang, C., Li, X., Huang, G., Fan, J., Jiang, Z., Jiang, Y., Dai, J., Ma, H., Zheng, S., Cai, Y., Dai, H., Zheng, X., Zhou, H., Ni, S., Jin, G., She, J. X., Yu, L., Polychronakos, C., Hu, Z., Zhou, Z., Weng, J., Shen, H. & Yang, T., Aug 1 2019, In : Diabetes Care. 42, 8, p. 1414-1421 8 p.

Research output: Contribution to journalArticle

9 Scopus citations

Identification of serum proteins and multivariate models for diagnosis and therapeutic monitoring of lung cancer

Ma, R., Xu, H., Wu, J., Sharma, A. K., Bai, S., Dun, B., Jing, C., Cao, H., Wang, Z., She, J-X. & Feng, J., Jan 1 2017, In : Oncotarget. 8, 12, p. 18901-18913 13 p.

Research output: Contribution to journalArticle

10 Scopus citations

IFIH1 polymorphisms are significantly associated with type 1 diabetes and IFIH1 gene expression in peripheral blood mononuclear cells

Liu, S., Wang, H., Jin, Y., Podolsky, R., Reddy, M. V. P. L., Pedersen, J., Bode, B., Reed, J., Steed, D., Anderson, S., Yang, P., Muir, A., Steed, L., Hopkins, D., Huang, Y., Purohit, S. B., Wang, C. Y., Steck, A. K., Montemari, A., Eisenbarth, G. & 2 others, Rewers, M. & She, J-X., Jan 1 2009, In : Human Molecular Genetics. 18, 2, p. 358-365 8 p.

Research output: Contribution to journalArticle

108 Scopus citations

IGF-binding proteins in type-1 diabetes are more severely altered in the presence of complications

Sharma, A. K., Purohit, S. B., Sharma, S., Bai, S., Zhi, W., Ponny, S. R., Hopkins, D., Steed, L., Bode, B., Anderson, S. W. & She, J-X., 2016, In : Frontiers in Endocrinology. 7, JAN, 2.

Research output: Contribution to journalArticle

9 Scopus citations

IL-12p40 is associated with type 1 diabetes in Caucasian-American families

Davoodi-Semiromi, A., Yang, J. J. & She, J. X., Jan 1 2002, In : Diabetes. 51, 7, p. 2334-2336 3 p.

Research output: Contribution to journalArticle

57 Scopus citations

IL4 and IL4Rα genes are not linked or associated with type 1 diabetes

Reimsnider, S. K., Eckenrode, S. E., Marron, M. P., Muir, A. & She, J. X., Feb 2000, In : Pediatric research. 47, 2, p. 246-249 4 p.

Research output: Contribution to journalArticle

Open Access
7 Scopus citations

Impaired Crkl expression contributes to the defective DNA binding of Stat5b in nonobese diabetic mice

Laloraya, M., Davoodi-Semiromi, A., Kumar, G. P., McDuffie, M. & She, J. X., Mar 2006, In : Diabetes. 55, 3, p. 734-741 8 p.

Research output: Contribution to journalArticle

16 Scopus citations

Independent variation and positive selection in env V1 and V2 domains within maternal-infant strains of human immunodeficiency virus type 1 in vivo

Lamers, S. L., Sleasman, J. W., Jin Xiong She, X. S., Barrie, K. A., Pomeroy, S. M., Barrett, D. J. & Goodenow, M. M., 1993, In : Journal of Virology. 67, 7, p. 3951-3960 10 p.

Research output: Contribution to journalArticle

Open Access
54 Scopus citations

Inflammatory serum proteins are severely altered in metastatic gastric adenocarcinoma patients from the Chinese population

Wang, J., Ma, R., Sharma, A. K., He, M., Xue, J., Wu, J., Dun, B., Li, G., Wang, X., Ji, M., She, J-X. & Tang, J., Apr 17 2015, In : PloS one. 10, 4, e0123985.

Research output: Contribution to journalArticle

8 Scopus citations

In reply [5]

Wang, C. Y., Yang, P. & She, J. X., Feb 1 2005, In : Nature Genetics. 37, 2, p. 112-113 2 p.

Research output: Contribution to journalLetter

3 Scopus citations

Insulin-dependent diabetes mellitus (IDDM) is associated with CTLA4 polymorphisms in multiple ethnic groups

Marron, M. P., Raffel, L. J., Garchon, H. J., Jacob, C. O., Serrano-Rios, M., Martinez Larrad, M. T., Teng, W. P., Park, Y., Zhang, Z. X., Goldstein, D. R., Tao, Y. W., Beaurain, G., Bach, J. F., Huang, H. S., Luo, D. F., Zeidler, A., Rotter, J. I., Yang, M. C. K., Modilevsky, T., Maclaren, N. K. & 1 others, She, J-X., Aug 1997, In : Human Molecular Genetics. 6, 8, p. 1275-1282 8 p.

Research output: Contribution to journalArticle

358 Scopus citations

Intrafamilial and case-control association analysis of d2s152 in insulin-dependent diabetes

Luo, D. F., Maclaren, N. K., Huang, H. S., Muir, A. & She, J. X., 1995, In : Autoimmunity. 21, 2, p. 143-147 5 p.

Research output: Contribution to journalArticle

25 Scopus citations

Joint modeling of longitudinal autoantibody patterns and progression to type 1 diabetes: results from the TEDDY study

Ancillary Studies, Diet, Genetics, Human Subjects/Publicity/Publications, Immune Markers, Infectious Agents, Laboratory Implementation, Maternal Studies, Psychosocial, Quality Assurance, Steering, Study Coordinators, Celiac Disease, Clinical Implementation & TEDDY study group, Nov 1 2017, In : Acta Diabetologica. 54, 11, p. 1009-1017 9 p.

Research output: Contribution to journalArticle

10 Scopus citations

KLHL5 knockdown increases cellular sensitivity to anticancer drugs

Schleifer, R. J., Li, S., Nechtman, W., Miller, E., Bai, S., Sharma, A. & She, J. X., Dec 1 2018, In : Oncotarget. 9, 100, p. 37429-37438 10 p.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Lack of an association of miR-938 SNP in IDDM10 with human type 1 diabetes

Mi, X., He, H., Deng, Y., Levin, A. M., She, J-X., Mi, Q. S. & Zhou, L., 2011, In : Diabetology and Metabolic Syndrome. 3, 1, 27.

Research output: Contribution to journalArticle

4 Scopus citations

Lack of correlation between the levels of soluble cytotoxic T-lymphocyte associated antigen-4 (CTLA-4) and the CT-60 genotypes

Purohit, S., Podolsky, R., Collins, C., Zheng, W., Schatz, D., Muir, A., Hopkins, D., Huang, Y. H. & She, J. X., Oct 31 2005, In : Journal of Autoimmune Diseases. 2, 8.

Research output: Contribution to journalArticle

52 Scopus citations

Large-scale discovery and validation studies demonstrate significant reductions in circulating levels of IL8, IL-1Ra, MCP-1, and MIP-1β in patients with type 1 diabetes

Purohit, S. B., Sharma, A. K., Hopkins, D., Steed, L., Bode, B., Anderson, S. W., Reed, J. C., Steed, R. D., Yang, T. & She, J-X., Sep 1 2015, In : Journal of Clinical Endocrinology and Metabolism. 100, 9, p. E1179-E1187

Research output: Contribution to journalArticle

8 Scopus citations

Longitudinal metabolome-wide signals prior to the appearance of a first islet autoantibody in children participating in the TEDDY study

Li, Q., Parikh, H., Butterworth, M. D., Lernmark, Å., Hagopian, W., Rewers, M., She, J. X., Toppari, J., Ziegler, A. G., Akolkar, B., Fiehn, O., Fan, S., Krischer, J. P., Rewers, M., Barbour, A., Bautista, K., Baxter, J., Felipe-Morales, D., Driscoll, K., Frohnert, B. I. & 236 others, Stahl, M., Gesualdo, P., Hoffman, M., Karban, R., Liu, E., Norris, J., Peacock, S., Shorrosh, H., Steck, A., Stern, M., Villegas, E., Waugh, K., Toppari, J., Simell, O. G., Adamsson, A., Ahonen, S., Åkerlund, M., Hakola, L., Hekkala, A., Holappa, H., Hyöty, H., Ikonen, A., Ilonen, J., Jäminki, S., Jokipuu, S., Karlsson, L., Kero, J., Kähönen, M., Knip, M., Koivikko, M. L., Koskinen, M., Koreasalo, M., Kurppa, K., Kytölä, J., Latva-Aho, T., Lindfors, K., Lönnrot, M., Mäntymäki, E., Mattila, M., Miettinen, M., Multasuo, K., Mykkänen, T., Niininen, T., Niinistö, S., Nyblom, M., Oikarinen, S., Ollikainen, P., Othmani, Z., Pohjola, S., Rajala, P., Rautanen, J., Riikonen, A., Riski, E., Pekkola, M., Romo, M., Ruohonen, S., Simell, S., Sjöberg, M., Stenius, A., Tossavainen, P., Vähä-Mäkilä, M., Vainionpää, S., Varjonen, E., Veijola, R., Viinikangas, I., Virtanen, S. M., She, J. X., Schatz, D., Hopkins, D., Steed, L., Bryant, J., Silvis, K., Haller, M., Gardiner, M., McIndoe, R., Sharma, A., Anderson, S. W., Jacobsen, L., Marks, J., Towe, P. D., Ziegler, A. G., Bonifacio, E., Gavrisan, A., Gezginci, C., Heublein, A., Hoffmann, V., Hummel, S., Keimer, A., Knopff, A., Koch, C., Koletzko, S., Ramminger, C., Roth, R., Scholz, M., Stock, J., Warncke, K., Wendel, L., Winkler, C., Lernmark, Å., Agardh, D., Aronsson, C. A., Ask, M., Bennet, R., Cilio, C., Engqvist, H., Ericson-Hallström, E., Fors, A., Fransson, L., Gard, T., Hansen, M., Jisser, H., Johansen, F., Jonsdottir, B., Jovic, S., Larsson, H. E., Lindström, M., Lundgren, M., Maziarz, M., Månsson-Martinez, M., Markan, M., Melin, J., Mestan, Z., Nilsson, C., Ottosson, K., Rahmati, K., Ramelius, A., Salami, F., Sjöberg, A., Sjöberg, B., Svensson, M., Törn, C., Wallin, A., Wimar, Å., Åberg, S., Hagopian, W. A., Killian, M., Crouch, C. C., Skidmore, J., Chavoshi, M., Hervey, R., Lyons, R., Meyer, A., Mulenga, D., Radtke, J., Romancik, M., Schmitt, D., Zink, S., Becker, D., Franciscus, M., Smith, M. E. D. E., Daftary, A., Klein, M. B., Yates, C., Krischer, J. P., Austin-Gonzalez, S., Avendano, M., Baethke, S., Brown, R., Burkhardt, B., Butterworth, M., Clasen, J., Cuthbertson, D., Dankyi, S., Eberhard, C., Fiske, S., Garmeson, J., Gowda, V., Heyman, K., Hsiao, B., Karges, C., Laras, F. P., Lee, H. S., Li, Q., Liu, S., Liu, X., Lynch, K., Maguire, C., Malloy, J., McCarthy, C., Merrell, A., Parikh, H., Quigley, R., Remedios, C., Shaffer, C., Smith, L., Smith, S., Sulman, N., Tamura, R., Tewey, D., Toth, M., Uusitalo, U., Vehik, K., Vijayakandipan, P., Wood, K., Yang, J., Abbondondolo, M., Ballard, L., Hadley, D., McLeod, W., Meulemans, S., Akolkar, B., Bourcier, K., Briese, T., Johnson, S. B., Triplett, E., Yu, L., Miao, D., Bingley, P., Williams, A., Chandler, K., Ball, O., Kelland, I., Grace, S., Erlich, H., Mack, S. J., Fear, A. L., Fiehn, O., Wikoff, B., Defelice, B., Grapov, D., Kind, T., Palazoglu, M., Valdiviez, L., Wancewicz, B., Wohlgemuth, G., Wong, J., Rich, S. S., Chen, W. M., Onengut-Gumuscu, S., Farber, E., Pickin, R. R., Davis, J., Davis, J., Gallo, D., Bonnie, J. & Campolieto, P., Mar 1 2020, In : Diabetes. 69, 3, p. 465-476 12 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Loss-of-Function Mutations in HPSE2 Cause the Autosomal Recessive Urofacial Syndrome

Pang, J., Zhang, S., Yang, P., Lee, B. H., Zhong, J., Zhang, Y., Ochoa, B., Agundez, J. A. G., Voelckel, M. A., Gu, W., Xiong, W., Mei, L., She, J-X. & Wang, C. Y., Jul 11 2010, In : American journal of human genetics. 86, 6, p. 957-962 6 p.

Research output: Contribution to journalArticle

46 Scopus citations
9 Scopus citations

Mapping DNA-binding domains of the autoimmune regulator protein

Purohit, S. B., Kumar, P. G., Laloraya, M. & She, J-X., Feb 18 2005, In : Biochemical and Biophysical Research Communications. 327, 3, p. 939-944 6 p.

Research output: Contribution to journalArticle

38 Scopus citations

Maternal anxiety about a child's diabetes risk in the TEDDY study: The potential role of life stress, postpartum depression, and risk perception

TEDDY study group, Jun 1 2015, In : Pediatric Diabetes. 16, 4, p. 287-298 12 p.

Research output: Contribution to journalArticle

11 Scopus citations

Maternal Anxiety Associated with Newborn Genetic Screening for Type 1 Diabetes

Johnson, S. B., Baughcum, A. E., Carmichael, S. K., She, J-X. & Schatz, D. A., Feb 1 2004, In : Diabetes Care. 27, 2, p. 392-397 6 p.

Research output: Contribution to journalArticle

33 Scopus citations

Maternal dietary supplement use and development of islet autoimmunity in the offspring: TEDDY study

The TEDDY study group, Feb 1 2019, In : Pediatric Diabetes. 20, 1, p. 86-92 7 p.

Research output: Contribution to journalArticle

6 Scopus citations

Maternal efforts to prevent type 1 diabetes in at-risk children

Baughcum, A. E., Johnson, S. B., Carmichael, S. K., Lewin, A. B., She, J-X. & Schatz, D. A., Apr 1 2005, In : Diabetes Care. 28, 4, p. 916-921 6 p.

Research output: Contribution to journalReview article

20 Scopus citations

Maternal understanding of infant diabetes risk: Differential effects of maternal anxiety and depression

Hood, K. K., Johnson, S. B., Baughcum, A. E., She, J-X. & Schatz, D. A., Oct 1 2006, In : Genetics in Medicine. 8, 10, p. 665-670 6 p.

Research output: Contribution to journalArticle

9 Scopus citations

Maternal use of dietary supplements during pregnancy is not associated with coeliac disease in the offspring: The Environmental Determinants of Diabetes in the Young (TEDDY) study

Yang, J., Tamura, R. N., Aronsson, C. A., Uusitalo, U. M., Lernmark, Å., Rewers, M., Hagopian, W. A., She, J. X., Toppari, J., Ziegler, A. G., Akolkar, B., Krischer, J. P., Norris, J. M., Virtanen, S. M. & Agardh, D., Feb 14 2017, In : British Journal of Nutrition. 117, 3, p. 466-472 7 p.

Research output: Contribution to journalArticle

8 Scopus citations

Metabolite-related dietary patterns and the development of islet autoimmunity

The TEDDY study group, Dec 1 2019, In : Scientific reports. 9, 1, 14819.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations

Methods, quality control and specimen management in an international multicentre investigation of type 1 diabetes: TEDDY

Vehik, K., Fiske, S. W., Logan, C. A., Agardh, D., Cilio, C. M., Hagopian, W., Simell, O., Roivainen, M., She, J. X., Briese, T., Oikarinen, S., Hyoty, H., Ziegler, A. G., Rewers, M., Lernmark, A., Akolkar, B., Krischer, J. P. & Burkhardt, B. R., Oct 2013, In : Diabetes/Metabolism Research and Reviews. 29, 7, p. 557-567 11 p.

Research output: Contribution to journalArticle

32 Scopus citations

Microarray analysis of gene expression in the kidneys of new- and post-onset diabetic NOD mice

Wilson, K. H. S., Eckenrode, S. E., Li, Q. Z., Ruan, Q. G., Yang, P., Shi, J. D., Davoodi-Semiromi, A., McIndoe, R. A., Croker, B. P. & She, J-X., Aug 1 2003, In : Diabetes. 52, 8, p. 2151-2159 9 p.

Research output: Contribution to journalArticle

52 Scopus citations

Microarray experimental design: Power and sample size considerations

Yang, M. C. K., Yang, J. J., McIndoe, R. A. & She, J. X., Apr 1 2004, In : Physiological Genomics. 16, p. 24-28 5 p.

Research output: Contribution to journalArticle

40 Scopus citations

MicroRNA-34a is induced via p53 during cisplatin nephrotoxicity and contributes to cell survival

Bhatt, K., Zhou, L., Mi, Q. S., Huang, S., She, J-X. & Dong, Z., Sep 2010, In : Molecular Medicine. 16, 9-10, p. 409-416 8 p.

Research output: Contribution to journalArticle

90 Scopus citations

Molecular cloning and characterization of a novel gene family of four ancient conserved domain proteins (ACDP)

Wang, C. Y., Shi, J. D., Yang, P., Kumar, P. G., Li, Q. Z., Run, Q. G., Su, Y., Scott, H. S., Kao, K. J. & She, J-X., Mar 13 2003, In : Gene. 306, 1-2, p. 37-44 8 p.

Research output: Contribution to journalArticle

72 Scopus citations

Molecular Cloning and Characterization of a Novel Mammalian Endo-apyrase (LALP1)

Shi, J. D., Kukar, T., Wang, C. Y., Li, Q. Z., Cruz, P. E., Davoodi-Semiromi, A., Yang, P., Gu, Y., Lian, W., Wu, D. H. & She, J-X., May 18 2001, In : Journal of Biological Chemistry. 276, 20, p. 17474-17478 5 p.

Research output: Contribution to journalArticle

39 Scopus citations

Molecular cloning and characterization of the mouse Acdp gene family

Wang, C. Y., Yang, P., Shi, J. D., Purohit, S., Guo, D., An, H., Gu, J. G., Ling, J., Dong, Z. & She, J. X., Jan 15 2004, In : BMC Genomics. 5, 7.

Research output: Contribution to journalArticle

37 Scopus citations

Molecular cloning and characterization of the mouse and human TUSP gene, a novel member of the tubby superfamily

Li, Q. Z., Wang, C. Y., Shi, J. D., Ruan, Q. G., Eckenrode, S., Davoodi-Semiromi, A., Kukar, T., Gu, Y., Lian, W., Wu, D. & She, J-X., Aug 8 2001, In : Gene. 273, 2, p. 275-284 10 p.

Research output: Contribution to journalArticle

23 Scopus citations

Molecular pathways altered by insulin B9-23 immunization

Eckenrode, S. E., Ruan, Q. G., Collins, C. D., Yang, P., McIndoe, R. A., Muir, A. & She, J-X., Jan 1 2004, In : Annals of the New York Academy of Sciences. 1037, p. 175-185 11 p.

Research output: Contribution to journalArticle

4 Scopus citations

Molecular phylogenies in the genus Mus: Comparative analysis of electrophoretic, scnDNA hybridization, and mtDNA RFLP data

SHE, J. X., BONHOMME, F., BOURSOT, P., THALER, L. & CATZEFLIS, F., Sep 1990, In : Biological Journal of the Linnean Society. 41, 1-3, p. 83-103 21 p.

Research output: Contribution to journalArticle

158 Scopus citations

Multiplex glycan bead array for high throughput and high content analyses of glycan binding proteins

Purohit, S. B., Li, T., Guan, W., Song, X., Song, J., Tian, Y., Li, L., Sharma, A. K., Dun, B., Mysona, D., Ghamande, S. A., Rungruang, B. J., Cummings, R. D., Wang, P. G. & She, J-X., Dec 1 2018, In : Nature communications. 9, 1, 258.

Research output: Contribution to journalArticle

21 Scopus citations

Multivariate analysis of genetic exchanges between Solea aegyptiaca and Solea senegalensis (Teleosts, Soleidae)

SHE, J. X., AUTEM, M., KOTULAS, G., PASTEUR, N. & BONHOMME, F., Jan 1 1987, In : Biological Journal of the Linnean Society. 32, 4, p. 357-371 15 p.

Research output: Contribution to journalArticle

108 Scopus citations

Mycophenolic acid inhibits migration and invasion of gastric cancer cells via multiple molecular pathways

Dun, B., Sharma, A., Teng, Y., Liu, H., Purohit, S., Xu, H., Zeng, L. & She, J. X., Nov 15 2013, In : PloS one. 8, 11, e81702.

Research output: Contribution to journalArticle

22 Scopus citations

NeuroD/Beta2 polymorphism is not associated with type 1 diabetes in Chinese, Korean, or Caucasian populations

Marron, M. P., Hopkins, D. I., She, J. X., Park, Y. S. & She, J. X., Apr 1999, In : Journal of Endocrine Genetics. 1, 2, p. 73-77 5 p.

Research output: Contribution to journalArticle

4 Scopus citations

Next-generation sequencing for viruses in children with rapid-onset type 1 diabetes

Lee, H. S., Briese, T., Winkler, C., Rewers, M., Bonifacio, E., Hyoty, H., Pflueger, M., Simell, O., She, J. X., Hagopian, W., Lernmark, A., Akolkar, B., Krischer, J. P. & Ziegler, A. G., Aug 2013, In : Diabetologia. 56, 8, p. 1705-1711 7 p.

Research output: Contribution to journalArticle

23 Scopus citations

No primary association between the 308 polymorphism in the tumor necrosis factor α promoter region and insulin-dependent diabetes mellitus

Deng, G. Y., Maclaren, N. K., Huang, H. S., Zhang, L. P. & She, J. X., Feb 1996, In : Human Immunology. 45, 2, p. 137-142 6 p.

Research output: Contribution to journalArticle

43 Scopus citations

Novel biomarkers in type 1 diabetes

Jin, Y. & She, J. X., 2012, In : Review of Diabetic Studies. 9, 4, p. 224-235 12 p.

Research output: Contribution to journalReview article

6 Scopus citations

Novel TSHβ subunit gene mutation causing congenital central hypothyroidism in a newborn male

Morales, A. E., Shi, J. D., Wang, C. Y., She, J. X. & Muir, A., Jan 1 2004, In : Journal of Pediatric Endocrinology and Metabolism. 17, 3, p. 355-359 5 p.

Research output: Contribution to journalArticle

14 Scopus citations

Nucleotide sequence of a novel HLA-DRB1 allele, DRB1*0806

She, J-X., Zhang, L. P., Scornik, J. & Wakeland, E. K., Jan 1 1994, In : Immunogenetics. 39, 1, 1 p.

Research output: Contribution to journalArticle

7 Scopus citations

Only multiple autoantibodies to islet cells (ICA), insulin, GAD65, IA-2 and IA-2β predict immune-mediated (type 1) diabetes in relatives

Maclaren, N., Lan, M., Coutant, R., Schatz, D., Silverstein, J., Muir, A., Clare-Salzer, M., She, J-X., Malone, J., Crockett, S., Schwartz, S., Quattrin, T., Desilva, M., Vander Vegt, P., Notkins, A. & Krischer, J., Jun 1999, In : Journal of Autoimmunity. 12, 4, p. 279-287 9 p.

Research output: Contribution to journalArticle

97 Scopus citations
6 Scopus citations