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Research Output

Pandemrix® vaccination is not associated with increased risk of islet autoimmunity or type 1 diabetes in the TEDDY study children

for the TEDDY Study Group, Jan 1 2018, In : Diabetologia. 61, 1, p. 193-202 10 p.

Research output: Contribution to journalArticle

5 Scopus citations

Paternally transmitted IDDM2 influences diabetes susceptibility despite biallelic expression of the insulin gene in human pancreas

Bui, M. M., Luo, D. F., She, J. Y., Maclaren, N. K., Muir, A., Thomson, G. & Jin-Xiong, S., Feb 1996, In : Journal of Autoimmunity. 9, 1, p. 97-103 7 p.

Research output: Contribution to journalArticle

27 Scopus citations

Persistence of multiple maternal genotypes of human immunodeficiency virus type I in infants infected by vertical transmission

Lamers, S. L., Sleasman, J. W., She, J. X., Barrie, K. A., Pomeroy, S. M., Barrett, D. J. & Goodenow, M. M., Jan 1994, In : Journal of Clinical Investigation. 93, 1, p. 380-390 11 p.

Research output: Contribution to journalArticle

76 Scopus citations

Pharmacophore-based discovery of new human dihydroorotate dehydrogenase inhibitor

Lu, P., Wang, Y., Ma, B., She, J., Zhang, Q., He, M. & Liu, Y., Jun 2014, In : Medicinal Chemistry. 10, 4, p. 402-408 7 p.

Research output: Contribution to journalArticle

3 Scopus citations
22 Scopus citations

Physiologic self antigens rapidly capacitate autoimmune disease-specific polyclonal CD4+CD25+ regulatory T cells

Setiady, Y. Y., Ohno, K., Samy, E. T., Bagavant, H., Qiao, H., Sharp, C., Jin, X. S. & Tung, K. S. K., Feb 1 2006, In : Blood. 107, 3, p. 1056-1062 7 p.

Research output: Contribution to journalArticle

48 Scopus citations

Plasma 25-Hydroxyvitamin D concentration and risk of islet autoimmunity

Norris, J. M., Lee, H. S., Frederiksen, B., Erlund, I., Uusitalo, U., Yang, J., Lernmark, Å., Simell, O., Toppari, J., Rewers, M., Ziegler, A. G., She, J-X., Onengut-Gumuscu, S., Chen, W. M., Rich, S. S., Sundvall, J., Akolkar, B., Krischer, J., Virtanen, S. M. & Hagopian, W., Jan 1 2018, In : Diabetes. 67, 1, p. 146-154 9 p.

Research output: Contribution to journalArticle

27 Scopus citations

Population genetics and functions of the autoimmune regulator (AIRE)

Kumar, P. G., Laloraya, M. & She, J. X., Jul 4 2002, In : Endocrinology and Metabolism Clinics of North America. 31, 2, p. 321-338 18 p.

Research output: Contribution to journalReview article

31 Scopus citations

Porous-wall hollow glass microspheres as novel potential nanocarriers for biomedical applications

Li, S., Nguyen, L., Xiong, H., Wang, M., Hu, T. C. C., She, J. X., Serkiz, S. M., Wicks, G. G. & Dynan, W. S., Feb 2010, In : Nanomedicine: Nanotechnology, Biology, and Medicine. 6, 1, p. 127-136 10 p.

Research output: Contribution to journalArticle

41 Scopus citations

Poststreptococcal reactive arthritis: Clinical characteristics and association with HLA-DR alleles

Ahmed, S., Ayoub, E. M., Scornik, J. C., Wang, C. Y. & She, J-X., Jun 1 1998, In : Arthritis and Rheumatism. 41, 6, p. 1096-1102 7 p.

Research output: Contribution to journalArticle

84 Scopus citations

Prediabetic markers in children with stress hyperglycemia

Bhisitkul, D. M., Vinik, A. I., Morrow, A. L., She, J. X., Shults, J., Powers, A. C. & Maclaren, N. K., Sep 1996, In : Archives of Pediatrics and Adolescent Medicine. 150, 9, p. 936-941 6 p.

Research output: Contribution to journalArticle

25 Scopus citations

Predicting islet cell autoimmunity and type 1 diabetes: An 8-year teddy study progress report

TEDDY study group, Jun 1 2019, In : Diabetes Care. 42, 6, p. 1051-1060 10 p.

Research output: Contribution to journalArticle

13 Scopus citations

Predicting progression to type 1 diabetes from ages 3 to 6 in islet autoantibody positive TEDDY children

The TEDDY study group, May 2019, In : Pediatric Diabetes. 20, 3, p. 263-270 8 p.

Research output: Contribution to journalArticle

5 Scopus citations

Prediction and prevention of type 1 diabetes.

Morales, A. E., She, J. X. & Schatz, D. A., Aug 2001, In : Current diabetes reports. 1, 1, p. 28-32 5 p.

Research output: Contribution to journalReview article

9 Scopus citations
75 Scopus citations

Prenatal and infant nutrition in the pathogenesis of type 1 diabetes implications for diagnosis and therapy

Muir, A. & She, J-X., Jan 1 2004, Perinatal Nutrition: Optimizing Infant Health and Development. CRC Press, p. 307-330 24 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Preservation of C-peptide secretion in subjects at high risk of developing type 1 diabetes mellitus - A new surrogate measure of non-progression?

Schatz, D., Cuthbertson, D., Atkinson, M., Salzer, M. C., Winter, W., Muir, A., Silverstein, J., Cook, R., Maclaren, N., She, J-X., Greenbaum, C. & Krischer, J., Jun 2004, In : Pediatric Diabetes. 5, 2, p. 72-79 8 p.

Research output: Contribution to journalArticle

30 Scopus citations

Prevalence of obesity was related to HLA-DQ in 2-4-year-old children at genetic risk for type 1 diabetes

Yang, J., Lernmark, Uusitalo, U. M., Lynch, K. F., Veijola, R., Winkler, C., Larsson, H. E., Rewers, M., She, J. X., Ziegler, A. G., Simell, O. G., Hagopian, W. A., Akolkar, B., Krischer, J. P. & Vehik, K., Dec 11 2014, In : International Journal of Obesity. 38, 12, p. 1491-1496 6 p.

Research output: Contribution to journalArticle

10 Scopus citations

Proficiency testing of human leukocyte antigen-DR and human leukocyte antigen-DQ genetic risk assessment for type 1 diabetes using dried blood spots

Dantonio, P., Meredith-Molloy, N., Hagopian, W. A., She, J. X., Akolkar, B., Cordovado, S. K., Hendrix, M., Henderson, L. O., Hannon, W. H. & Vogt, R. F., Jul 2010, In : Journal of Diabetes Science and Technology. 4, 4, p. 929-941 13 p.

Research output: Contribution to journalArticle

6 Scopus citations

Progression from islet autoimmunity to clinical type 1 diabetes is influenced by genetic factors: Results from the prospective TEDDY study

Beyerlein, A., Bonifacio, E., Vehik, K., Hippich, M., Winkler, C., Frohnert, B. I., Steck, A. K., Hagopian, W. A., Krischer, J. P., Lernmark, Å., Rewers, M. J., She, J. X., Toppari, J., Akolkar, B., Rich, S. S. & Ziegler, A. G., Sep 1 2019, In : Journal of medical genetics. 56, 9, p. 602-605 4 p.

Research output: Contribution to journalArticle

4 Scopus citations

Prospective assessment in newborns of diabetes autoimmunity (PANDA): Maternal understanding of infant diabetes risk

Carmichael, S. K., Johnson, S. B., Baughcum, A., North, K., Hopkins, D., Dukes, M. G., She, J-X. & Schatz, D. A., Mar 1 2003, In : Genetics in Medicine. 5, 2, p. 77-83 7 p.

Research output: Contribution to journalArticle

35 Scopus citations

Prospective virome analyses in young children at increased genetic risk for type 1 diabetes

The TEDDY study group, Dec 1 2019, In : Nature Medicine. 25, 12, p. 1865-1872 8 p.

Research output: Contribution to journalArticle

Open Access
16 Scopus citations

Protein microarrays to detect protein-protein interactions using red and green fluorescent proteins

Kukar, T., Eckenrode, S., Gu, Y., Lian, W., Megginson, M., She, J. X. & Wu, D., Jul 1 2002, In : Analytical Biochemistry. 306, 1, p. 50-54 5 p.

Research output: Contribution to journalArticle

84 Scopus citations

Proteins of TNF-α and IL6 pathways are elevated in serum of type-1 diabetes patients with microalbuminuria

Purohit, S. B., Sharma, A. K., Zhi, W., Bai, S., Hopkins, D., Steed, L., Bode, B., Anderson, S. W., Reed, J. C., Steed, R. D. & She, J-X., Jan 31 2018, In : Frontiers in immunology. 9, JAN, 154.

Research output: Contribution to journalArticle

4 Scopus citations

Proteomic analysis of SUMO4 substrates in HEK293 cells under serum starvation-induced stress

Guo, D., Han, J., Adam, B. L., Colburn, N. H., Wang, M-H., Dong, Z., Eizirik, D. L., She, J-X. & Wang, C. Y., Dec 2 2005, In : Biochemical and Biophysical Research Communications. 337, 4, p. 1308-1318 11 p.

Research output: Contribution to journalArticle

70 Scopus citations

Proteomic approach to identify biomarkers for invasive cervix cancer - a prospective pilot study

Mysona, D., Pyrzak, A., Allen, J., Powell, M., Kleven, D., Zhi, W., Sharma, A., Bai, S., She, J. X., Rungruang, B. & Ghamande, S., Jan 1 2018, In : European Journal of Gynaecological Oncology. 39, 5, p. 737-742 6 p.

Research output: Contribution to journalArticle

Proteomic technologies for the discovery of type 1 diabetes biomarkers

Zhi, W., Purohit, S., Carey, C., Wang, M. & She, J. X., Jul 2010, In : Journal of Diabetes Science and Technology. 4, 4, p. 993-1002 10 p.

Research output: Contribution to journalReview article

33 Scopus citations

Psychological manifestations of celiac disease autoimmunity in young children

The TEDDY study group, Mar 2017, In : Pediatrics. 139, 3, e20162848.

Research output: Contribution to journalArticle

18 Scopus citations

Rapid decrease of RNA level of a novel mouse mitochondria solute carrier protein (Mscp) gene at 4-5 weeks of age

Li, Q. Z., Eckenrode, S., Ruan, Q. G., Wang, C. Y., Shi, J. D., McIndoe, R. A. & She, J-X., 2001, In : Mammalian Genome. 12, 11, p. 830-836 7 p.

Research output: Contribution to journalArticle

4 Scopus citations

Reduced serum vitamin D-binding protein levels are associated with type 1 diabetes

Blanton, D., Han, Z., Bierschenk, L., Linga-Reddy, M. V. P., Wang, H., Clare-Salzler, M., Haller, M., Schatz, D., Myhr, C., She, J-X., Wasserfall, C. & Atkinson, M., Oct 2011, In : Diabetes. 60, 10, p. 2566-2570 5 p.

Research output: Contribution to journalArticle

80 Scopus citations

Relative predispositional effects of HLA class II DRB1-DQB1 haplotypes and genotypes on type 1 diabetes: A meta-analysis

Thomson, G., Valdes, A. M., Noble, J. A., Kockum, I., Grote, M. N., Najman, J., Erlich, H. A., Cucca, F., Pugliese, A., Steenkiste, A., Dorman, J. S., Caillat-Zucman, S., Hermann, R., Ilonen, J., Lambert, A. P., Bingley, P. J., Gillespie, K. M., Lernmark, Å., Sanjeevi, C. B., Rønningen, K. S. & 32 others, Undlien, D. E., Thorsby, E., Petrone, A., Buzzetti, R., Koeleman, B. P. C., Roep, B. O., Saruhan-Direskeneli, G., Uyar, F. A., Günoz, H., Gorodezky, C., Alaez, C., Boehm, B. O., Mlynarski, W., Ikegami, H., Berrino, M., Fasano, M. E., Dametto, E., Israel, S., Brautbar, C., Santiago-Cortes, A., Frazer De Llado, T., She, J-X., Bugawan, T. L., Rotter, J. I., Raffel, L., Zeidler, A., Leyva-Cobian, F., Hawkins, B. R., Chan, S. H., Castano, L., Pociot, F. & Nerup, J., Aug 2007, In : Tissue Antigens. 70, 2, p. 110-127 18 p.

Research output: Contribution to journalArticle

116 Scopus citations

Respiratory infections are temporally associated with initiation of type 1 diabetes autoimmunity: the TEDDY study

On behalf of the TEDDY Study Group, Oct 1 2017, In : Diabetologia. 60, 10, p. 1931-1940 10 p.

Research output: Contribution to journalArticle

38 Scopus citations

Reversion of β-cell autoimmunity changes risk of type 1 diabetes: TEDDY study

Vehik, K., Lynch, K. F., Schatz, D. A., Akolkar, B., Hagopian, W., Rewers, M., She, J. X., Simell, O., Toppari, J., Ziegle, A. G., Lernmark, A., Bonifacio, E. & Krischer, J. P., Sep 1 2016, In : Diabetes Care. 39, 9, p. 1535-1542 8 p.

Research output: Contribution to journalArticle

25 Scopus citations
21 Scopus citations

Role of type 1 diabetes- Associated snps on risk of autoantibody positivity in the TEDDY study

Törn, C., Hadley, D., Lee, H. S., Hagopian, W., Lernmark, Å., Simell, O., Rewers, M., Ziegler, A., Schatz, D., Akolkar, B., Onengut-Gumuscu, S., Chen, W. M., Toppari, J., Mykkänen, J., Ilonen, J., Rich, S. S., She, J-X., Steck, A. K. & Krischer, J., May 2015, In : Diabetes. 64, 5, p. 1818-1829 12 p.

Research output: Contribution to journalArticle

60 Scopus citations

rs2476601 T allele (R620W) defines high-risk PTPN22 type I diabetes-associated haplotypes with preliminary evidence for an additional protective haplotype

Type I Diabetes Genetics Consortium, Dec 2009, In : Genes and Immunity. 10, p. S21-S26

Research output: Contribution to journalArticle

21 Scopus citations
19 Scopus citations

Sequence divergence of B2m alleles of wild Mus musculus and Mus spretus implies positive selection

Hermel, E., Robinson, P. J., She, J. X. & Fischer Lindahl, K., Apr 1 1993, In : Immunogenetics. 38, 2, p. 106-116 11 p.

Research output: Contribution to journalArticle

28 Scopus citations

Serum Dickkopf-1 (DKK1) is significantly lower in patients with lung cancer but is rapidly normalized after treatment

Xu, H., Wu, J., Chen, B., Li, M., Tian, Y., He, M., Xue, J., Wang, J., Bai, S., Sharma, A. K., Liu, H., Tang, J. & She, J-X., Jan 1 2014, In : American Journal of Translational Research. 6, 6, p. 850-856 7 p.

Research output: Contribution to journalArticle

15 Scopus citations
9 Scopus citations

Serum protein profile at remission can accurately assess therapeutic outcomes and survival for serous ovarian cancer

Wang, J., Sharma, A., Ghamande, S. A., Bush, S., Ferris, D., Zhi, W., He, M., Wang, M., Wang, X., Miller, E., Hopkins, D., Macfee, M., Guan, R., Tang, J. & She, J. X., Nov 11 2013, In : PloS one. 8, 11, e78393.

Research output: Contribution to journalArticle

9 Scopus citations

SUMO4 and its role in type 1 diabetes pathogenesis

Wang, C. Y. & She, J. X., Feb 1 2008, In : Diabetes/Metabolism Research and Reviews. 24, 2, p. 93-102 10 p.

Research output: Contribution to journalReview article

44 Scopus citations

SUMO wrestling with type 1 diabetes

Li, M., Guo, D., Isales, C. M., Eizirik, D. L., Atkinson, M., She, J. X. & Wang, C. Y., Jul 1 2005, In : Journal of Molecular Medicine. 83, 7, p. 504-513 10 p.

Research output: Contribution to journalReview article

72 Scopus citations

Susceptibility to type I diabetes: HLA-DQ and DR revisited

She, J. X., Jul 1996, In : Immunology Today. 17, 7, p. 323-329 7 p.

Research output: Contribution to journalComment/debate

302 Scopus citations
2 Scopus citations

Synthesis and in vitro evaluation of 1,3,4-thiadiazol-2-yl urea derivatives as novel AChE inhibitors

Xue, X. J., Wang, Y. B., Lu, P., Shang, H. F., She, J. X., Xia, L. X., Qian, H. & Huang, W. L., Jun 2014, In : Chemical and Pharmaceutical Bulletin. 62, 6, p. 524-527 4 p.

Research output: Contribution to journalArticle

5 Scopus citations

Synthesis of saracatinib

Shang, H. F., Wang, Y. B., Zhao, D. M., Zhang, Q. & She, J-X., Dec 15 2011, In : Chinese Journal of New Drugs. 20, 23, p. 2363-2366 4 p.

Research output: Contribution to journalArticle

Systematic evaluation of 640 FDA drugs for their effect on CD4 +Foxp3+ regulatory T cells using a novel cell-based high throughput screening assay

Mao, R., Xiao, W., Liu, H., Chen, B., Yi, B., Kraj, P. & She, J-X., May 15 2013, In : Biochemical Pharmacology. 85, 10, p. 1513-1524 12 p.

Research output: Contribution to journalArticle

13 Scopus citations

TEDDY - The Environmental Determinants of Diabetes in the Young: An observational clinical trial

Hagopian, W. A., Lernmark, Å., Rewers, M. J., Simell, O. G., She, J. X., Ziegler, A. G., Krischer, J. P. & Akolkar, B., Oct 2006, Immunology of Diabetes IV: Progress in Our Understanding. Blackwell Publishing Inc., p. 320-326 7 p. (Annals of the New York Academy of Sciences; vol. 1079).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

71 Scopus citations

Temporal development of the gut microbiome in early childhood from the TEDDY study

Stewart, C. J., Ajami, N. J., O’Brien, J. L., Hutchinson, D. S., Smith, D. P., Wong, M. C., Ross, M. C., Lloyd, R. E., Doddapaneni, H. V., Metcalf, G. A., Muzny, D., Gibbs, R. A., Vatanen, T., Huttenhower, C., Xavier, R. J., Rewers, M., Hagopian, W., Toppari, J., Ziegler, A. G., She, J-X. & 6 others, Akolkar, B., Lernmark, A., Hyoty, H., Vehik, K., Krischer, J. P. & Petrosino, J. F., Oct 25 2018, In : Nature. 562, 7728, p. 583-588 6 p.

Research output: Contribution to journalArticle

198 Scopus citations