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Research Output

The 6 year incidence of diabetes-associated autoantibodies in genetically at-risk children: the TEDDY study

Krischer, J. P., Lynch, K. F., Schatz, D. A., Ilonen, J., Lernmark, Å., Hagopian, W. A., Rewers, M. J., She, J. X., Simell, O. G., Toppari, J., Ziegler, A. G., Akolkar, B. & Bonifacio, E., May 1 2015, In : Diabetologia. 58, 5, p. 980-987 8 p.

Research output: Contribution to journalArticle

171 Scopus citations

The application of genomic and proteomic technologies in predictive, preventive and personalized medicine

Collins, C. D., Purohit, S., Podolsky, R. H., Zhao, H. S., Schatz, D., Eckenrode, S. E., Yang, P., Hopkins, D., Muir, A., Hoffman, M., McIndoe, R. A., Rewers, M. & She, J. X., Nov 2006, In : Vascular Pharmacology. 45, 5, p. 258-267 10 p.

Research output: Contribution to journalArticle

47 Scopus citations

The autoimmune regulator (Aire) controls iNKT cell development and maturation

Mi, Q. S., Deng, Z. B., Joshi, S. K., Wang, Z. Z., Zhou, L., Eckenrode, S., Joshi, R., Ly, D., Yi, B., Delovitch, T. L. & She, J-X., Jun 2006, In : Nature Medicine. 12, 6, p. 624-626 3 p.

Research output: Contribution to journalArticle

6 Scopus citations

The autoimmune regulator (Aire) controls iNKT cell development and maturation.

Mi, Q. S., Deng, Z. B., Joshi, S. K., Wang, Z. Z., Zhou, L., Eckenrode, S., Joshi, R., Ly, D., Yi, B., Delovitch, T. L. & She, J. X., Sep 1 2006, In : Nature Medicine. 12, 9

Research output: Contribution to journalArticle

The Autoimmune Regulator (AIRE) Is a DNA-binding Protein

Kumar, P. G., Laloraya, M., Wang, C. Y., Ruan, Q. G., Davoodi-Semiromi, A., Kao, K. J. & She, J-X., Nov 2 2001, In : Journal of Biological Chemistry. 276, 44, p. 41357-41364 8 p.

Research output: Contribution to journalArticle

123 Scopus citations

The autoimmune regulator directly controls the expression of genes critical for thymic epithelial function

Ruan, Q. G., Tung, K., Elsenman, D., Setiady, Y., Eckenrode, S., Yi, B., Purohit, S. B., Zheng, W. P., Zhang, Y., Peltonen, L. & She, J-X., Jun 1 2007, In : Journal of Immunology. 178, 11, p. 7173-7180 8 p.

Research output: Contribution to journalArticle

38 Scopus citations

The Environmental Determinants of Diabetes in the Young (TEDDY): Genetic criteria and international diabetes risk screening of 421 000 infants

Hagopian, W. A., Erlich, H., Lernmark, Å., Rewers, M., Ziegler, A. G., Simell, O., Akolkar, B., Vogt, R., Blair, A., Ilonen, J., Krischer, J. & She, J., Dec 2011, In : Pediatric Diabetes. 12, 8, p. 733-743 11 p.

Research output: Contribution to journalArticle

125 Scopus citations

The environmental determinants of diabetes in the young (TEDDY) study

Rewers, M., She, J. X., Ziegler, A. G., Simell, O. G., Lernmark, Å., Hagopian, W. A., Krischer, J. P. & Akolkar, B., Dec 2008, Immunology of Diabetes V From Bench to Bedside. Blackwell Publishing Inc., p. 1-13 13 p. (Annals of the New York Academy of Sciences; vol. 1150).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

151 Scopus citations

The Environmental Determinants of Diabetes in the Young (TEDDY) study: Study design

Krischer, J., Rewers, M., Barriga, K., Baxter, J., Deas, A., Eisenbarth, G., Emery, L., Gesualdo, P., Hoffman, M., Norris, J., Waugh, K., Weber, S., She, J-X., Muir, A., Schatz, D., Hopkins, D., Steed, L., Silvis, K., Shankar, M., huang, Y. H. & 84 others, Yang, P., Zheng, W. P., Wang, H. J., English, K., McIndoe, R. A., Ziegler, A. G., Bonifacio, E., Baumgarten, A., Hummel, S., Kersting, M., Koenig, S., Knopff, A., Locher, A., Roth, R., Schoen, S., Schwaiger, P., Sichert-Hellert, W., Winkler, C., Zimmermann, D., Simell, O. G., Nanto-Salonen, K., Ilonen, J., Knip, M., Veijola, R., Simell, T., Uusitalo, U., Hyöty, H., Virtanen, S. M., Kronberg-Kippila̧, C., Torma, M., Ruohonen, E., Romo, M., Mantymaki, E., Niininen, T., Nyblom, M., Stenius, A., Lernmark, Å., Almgren, P., Andrén-Aronsson, C., Andersson, E., Bianconi-Svensson, S., Carlsson, U. M., Cilio, C., Gerardsson, J., Gustavsson, B., Hansson, A., Hansson, G., Hansson, I., Ivarsson, S., Larsson, H., Karlsson, E., Katsarou, A., Lernmark, B., Massadakis, T., Nilsson, A., Järvirova, M. S., Sjöberg, B., Wallin, A., Wimar, Å., Hagopian, W. A., Brantley, M., Cowen, C., Hui, P., Hay, K. M., Jackson, M., Stepikova, V., Ugale, J., Krischer, J. P., Bray, C., Cuthbertson, D., Gowda, V., Hunt, K., Liu, S., Malloy, J., McCarthy, C., McLeod, W., Moyers, S., Nallamshetty, L., Smith, S., Akolkar, B., Briese, T., Erlich, H., Bennett Johnson, S. & Oberste, S., Oct 2007, In : Pediatric Diabetes. 8, 5, p. 286-298 13 p.

Research output: Contribution to journalArticle

183 Scopus citations

The Environmental Determinants of Diabetes in the Young (TEDDY) Study: 2018 Update

The TEDDY study group, Dec 1 2018, In : Current diabetes reports. 18, 12, 136.

Research output: Contribution to journalReview article

13 Scopus citations

The expression of inflammatory genes is upregulated in peripheral blood of patients with type 1 diabetes

Jin, Y., Sharma, A. K., Davis, C. M., Hopkins, D., Wang, X., Robertson, D. G., Bode, B., Anderson, S. W., Reed, J. C., Steed, R. D., Steed, L. & She, J-X., Sep 2013, In : Diabetes Care. 36, 9, p. 2794-2802 9 p.

Research output: Contribution to journalArticle

24 Scopus citations

The Generation and Maintenance of MHC Class II Gene Polymorphism in Rodents

Wakeland, E. K., Boehme, S. & She, J. X., Feb 1990, In : Immunological Reviews. 113, 1, p. 207-226 20 p.

Research output: Contribution to journalArticle

39 Scopus citations

The generation of MHC class II gene polymorphism in the genus Mus

SHE, J. X., BOEHME, S., WANG, T. W., BONHOMME, F. & WAKELAND, E. K., Sep 1990, In : Biological Journal of the Linnean Society. 41, 1-3, p. 141-161 21 p.

Research output: Contribution to journalArticle

18 Scopus citations

The gene responsible for autoimmune polyglandular syndrome type 1 maps to chromosome 21q22.3 in US patients

Chen, Q. Y., Lan, M. S., She, J. X. & Maclaren, N. K., Apr 1998, In : Journal of Autoimmunity. 11, 2, p. 177-183 7 p.

Research output: Contribution to journalArticle

16 Scopus citations

The heterogeneity of islet autoantibodies and the progression of islet failure in type 1 diabetic patients

Liu, J., Bian, L., Ji, L., Chen, Y., Chen, H., Gu, Y., Ma, B., Gu, W., Xu, X., Shi, Y., Wang, J., Zhu, D., Sun, Z., Ma, J., Jin, H., Shi, X., Miao, H., Xin, B., Zhu, Y., Zhang, Z. & 52 others, Bu, R., Xu, L., Shi, G., Tang, W., Li, W., Zhou, D., Liang, J., Cheng, X., Shi, B., Dong, J., Hu, J., Fang, C., Zhong, S., Yu, W., Lu, W., Wu, C., Qian, L., Yu, J., Gao, J., Fei, X., Zhang, Q., Wang, X., Cui, S., Cheng, J., Xu, N., Wang, G., Han, G., Xu, C., Xie, Y., An, M., Zhang, W., Wang, Z., Cai, Y., Fu, Q., Fu, Y., Zheng, S., Yang, F., Hu, Q., Dai, H., Jin, Y., Zhang, Z., Xu, K., Li, Y., Shen, J., Zhou, H., He, W., Zheng, X., Han, X., Yu, L., She, J-X., Zhang, M. & Yang, T., Sep 1 2016, In : Science China Life Sciences. 59, 9, p. 930-939 10 p.

Research output: Contribution to journalArticle

5 Scopus citations

The human gut microbiome in early-onset type 1 diabetes from the TEDDY study

Vatanen, T., Franzosa, E. A., Schwager, R., Tripathi, S., Arthur, T. D., Vehik, K., Lernmark, Å., Hagopian, W. A., Rewers, M. J., She, J-X., Toppari, J., Ziegler, A. G., Akolkar, B., Krischer, J. P., Stewart, C. J., Ajami, N. J., Petrosino, J. F., Gevers, D., Lähdesmäki, H., Vlamakis, H. & 2 others, Huttenhower, C. & Xavier, R. J., Oct 25 2018, In : Nature. 562, 7728, p. 589-594 6 p.

Research output: Contribution to journalArticle

126 Scopus citations

The IDDMK1,222 retrovirus is not detectable in either mRNA or genomic DNA from patients with type 1 diabetes

Muir, A., Ruan, Q. G., Marron, M. P. & She, J-X., Jan 1999, In : Diabetes. 48, 1, p. 219-222 4 p.

Research output: Contribution to journalArticle

26 Scopus citations

The IL-10 and IFN-γ pathways are essential to the potent immunosuppressive activity of cultured CD8+ NKT-like cells

Zhou, L., Wang, H., Zhong, X., Jin, Y., Mi, Q. S., Sharma, A. K., McIndoe, R. A., Garge, N., Podolsky, R. & She, J-X., Jul 29 2008, In : Genome Biology. 9, 7, R119.

Research output: Contribution to journalArticle

11 Scopus citations

The influence of type 1 diabetes genetic susceptibility regions, age, sex, and family history on the progression from multiple autoantibodies to type 1 diabetes: A teddy study report

Krischer, J. P., Liu, X., Lernmark, Å., Hagopian, W. A., Rewers, M. J., She, J. X., Toppari, J., Ziegler, A. G. & Akolkar, B., Dec 1 2017, In : Diabetes. 66, 12, p. 3122-3129 8 p.

Research output: Contribution to journalArticle

48 Scopus citations

The relationship between breastfeeding and reported respiratory and gastrointestinal infection rates in young children

TEDDY study group, Sep 18 2019, In : BMC pediatrics. 19, 1, 339.

Research output: Contribution to journalArticle

Open Access

The relationship between humoral and cellular immunity to IA-2 in IDDM

Ellis, T. M., Schatz, D. A., Ottendorfer, E. W., Lan, M. S., Wasserfall, C., Salisbury, P. J., She, J. X., Notkins, A. L., Maclaren, N. K. & Atkinson, M. A., 1998, In : Diabetes. 47, 4, p. 566-569 4 p.

Research output: Contribution to journalArticle

43 Scopus citations

Tie2cre-induced inactivation of the miRNA-processing enzyme Dicer disrupts invariant NKT cell development

Zhou, L., Seo, K. H., He, H. Z., Pacholczyk, R. W., Meng, D. M., Li, C. G., Xu, J., She, J-X., Dong, Z. & Mi, Q. S., Jun 23 2009, In : Proceedings of the National Academy of Sciences of the United States of America. 106, 25, p. 10266-10271 6 p.

Research output: Contribution to journalArticle

76 Scopus citations

Time-resolved autoantibody profiling facilitates stratification of preclinical type 1 diabetes in children

for the TEDDY Study Group*, Jan 1 2019, In : Diabetes. 68, 1, p. 119-130 12 p.

Research output: Contribution to journalArticle

11 Scopus citations

TNP-ATP-resistant P2X ionic current on the central terminals and somata of rat primary sensory neurons

Tsuzuki, K., Ase, A., Séguéla, P., Nakatsuka, T., Wang, C. Y., She, J. X. & Gu, J. G., Jun 1 2003, In : Journal of Neurophysiology. 89, 6, p. 3235-3242 8 p.

Research output: Contribution to journalArticle

28 Scopus citations

To screen or not to screen for pre-type 1 diabetes?

Schatz, D., Krischer, J. & She, J. X., May 11 2002, In : Hormone Research. 57, SUPPL. 1, p. 12-17 6 p.

Research output: Contribution to journalArticle

6 Scopus citations

Toxicity assessment of 7 anticancer compounds in zebrafish

Gao, X. P., Feng, F., Zhang, X. Q., Liu, X. X., Wang, Y. B., She, J. X., He, Z. H. & He, M. F., Jan 1 2014, In : International Journal of Toxicology. 33, 2, p. 98-105 8 p.

Research output: Contribution to journalArticle

16 Scopus citations

Transcriptomic changes induced by mycophenolic acid in gastric cancer cells

Dun, B., Sharma, A., Xu, H., Liu, H., Bai, S., Zeng, L. & She, J. X., 2014, In : American Journal of Translational Research. 6, 1, p. 28-42 15 p.

Research output: Contribution to journalArticle

15 Scopus citations

Transracial evidence for the influence of the homologous HLA DR-DQ haplotype on transmission of HLA DR4 haplotypes to diabetic children

Park, Y. S., She, J. X., Noble, J. A., Erlich, H. A. & Eisenbarth, G. S., 2001, In : Tissue Antigens. 57, 3, p. 185-191 7 p.

Research output: Contribution to journalArticle

15 Scopus citations

Tumor profiling of co-regulated receptor tyrosine kinase and chemoresistant genes reveal different targeting options for lung and gastroesophageal cancers

Wu, J., Li, S., Ma, R., Sharma, A. K., Bai, S., Dun, B., Cao, H., Jing, C., She, J-X. & Feng, J., Jan 1 2016, In : American Journal of Translational Research. 8, 12, p. 5729-5740 12 p.

Research output: Contribution to journalArticle

4 Scopus citations
12 Scopus citations

Type 1 diabetes patients have significantly lower frequency of plasmacytoid dendritic cells in the peripheral blood

Chen, X., Makala, L. H. C., Jin, Y., Hopkins, D., Muir, A., Garge, N., Podolsky, R. H. & She, J. X., Dec 2008, In : Clinical Immunology. 129, 3, p. 413-418 6 p.

Research output: Contribution to journalArticle

34 Scopus citations

Vascular endothelium summary statement VI: Research directions for the 21st century

Mensah, G. A., Catravas, J. D., Engelgau, M. M., Hooper, W. C., Madeddu, P., Ryan, U. S., She, J. X., Reed, E., Vinicor, F. & Yacoub, M. H., May 2007, In : Vascular Pharmacology. 46, 5 SPEC. ISS., p. 330-332 3 p.

Research output: Contribution to journalArticle

5 Scopus citations