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Research Output

Article

Characterization of mutations in patients with autoimmune polyglandular syndrome type 1 (APS1)

Wang, C. Y., Davoodi-Semiromi, A., Huang, W., Connor, E., Shi, J. D. & She, J-X., Dec 1 1998, In : Human Genetics. 103, 6, p. 681-685 5 p.

Research output: Contribution to journalArticle

114 Scopus citations

Characterizations of candidate genes for IDD susceptibility from the diabetes-prone NOD mouse strain

Chesnut, K., She, J. X., Cheng, I., Muralidharan, K. & Wakeland, E. K., Oct 1 1993, In : Mammalian Genome. 4, 10, p. 549-554 6 p.

Research output: Contribution to journalArticle

27 Scopus citations

Chemokine (c-c motif) ligand 2 (ccl2) in sera of patients with type 1 diabetes and diabetic complications

Guan, R., Purohit, S. B., Wang, H., Bode, B., Reed, J. C., Steed, R. D., Anderson, S. W., Steed, L., Hopkins, D., Xia, C. & She, J-X., 2011, In : PloS one. 6, 4, e17822.

Research output: Contribution to journalArticle

19 Scopus citations

Children followed in the TEDDY study are diagnosed with type 1 diabetes at an early stage of disease

Elding Larsson, H., Vehik, K., Gesualdo, P., Akolkar, B., Hagopian, W., Krischer, J., Lernmark, Å., Rewers, M., Simell, O., She, J. X., Ziegler, A. & Haller, M. J., Mar 2014, In : Pediatric Diabetes. 15, 2, p. 118-126 9 p.

Research output: Contribution to journalArticle

39 Scopus citations

Chromosomal localization and complete genomic sequence of the murine autoimmune regulator gene (Aire)

Shi, J. D., Wang, C. Y., Marron, M. P., Ruan, Q. G., Huang, Y. Q., Detter, J. C. & She, J-X., Jan 1 1999, In : Autoimmunity. 31, 1, p. 47-53 7 p.

Research output: Contribution to journalArticle

5 Scopus citations

Chronic inflammatory demyelinating polyradiculoneuropathy in two children with type 1 diabetes mellitus

Fudge, E., Carol, J., She, J. X., Dosch, M., Atkinson, M. & Muir, A., Dec 1 2005, In : Pediatric Diabetes. 6, 4, p. 244-248 5 p.

Research output: Contribution to journalArticle

8 Scopus citations

Clinical calculator predictive of chemotherapy benefit in stage 1A uterine papillary serous cancers

Mysona, D. P., Tran, L. K. H., Tran, P. M. H., Gehrig, P. A., Van Le, L., Ghamande, S., Rungruang, B. J., Java, J., Mann, A. K., Liao, J., Kapp, D. S., Santos, B. D., She, J. X. & Chan, J. K., Jan 2020, In : Gynecologic Oncology. 156, 1, p. 77-84 8 p.

Research output: Contribution to journalArticle

2 Scopus citations

Cloning of Aire, the mouse homologue of the autoimmune regulator (AIRE) gene responsible for autoimmune polyglandular syndrome Type 1 (APS1)

Wang, C. Y., Shi, J. D., Davoodi-Semiromi, A. & She, J. X., Feb 1 1999, In : Genomics. 55, 3, p. 322-326 5 p.

Research output: Contribution to journalArticle

38 Scopus citations

Combinations of HLA DR and DQ molecules determine the susceptibility to insulin-dependent diabetes mellitus in Koreans

Park, Y. S., Wang, C. Y., Ko, K. W., Yang, S. W., Park, M., Yang, M. C. K. & She, J. X., Dec 1 1998, In : Human Immunology. 59, 12, p. 794-801 8 p.

Research output: Contribution to journalArticle

49 Scopus citations

Common susceptibility and transmission pattern of human leukocyte antigen DRB1-DQB1 haplotypes to Korean and Caucasian patients with type 1 diabetes

Park, Y., She, J. X., Wang, C. Y., Lee, H., Babu, S., Erlich, H. A., Noble, J. A. & Eisenbarth, G. S., Dec 1 2000, In : Journal of Clinical Endocrinology and Metabolism. 85, 12, p. 4538-4542 5 p.

Research output: Contribution to journalArticle

25 Scopus citations

Complement gene variants in relation to autoantibodies to beta cell specific antigens and type 1 diabetes in the TEDDY Study

Törn, C., Liu, X., Hagopian, W., Lernmark, Å., Simell, O., Rewers, M., Ziegler, A. G., Schatz, D., Akolkar, B., Onengut-Gumuscu, S., Chen, W. M., Toppari, J., Mykkänen, J., Ilonen, J., Rich, S. S., She, J-X., Sharma, A. K., Steck, A. & Krischer, J., Jun 16 2016, In : Scientific reports. 6, 27887.

Research output: Contribution to journalArticle

16 Scopus citations

Confirmation of novel type 1 diabetes risk loci in families

Cooper, J. D., Howson, J. M. M., Smyth, D., Walker, N. M., Stevens, H., Yang, J. H. M., She, J. X., Eisenbarth, G. S., Rewers, M., Todd, J. A., Akolkar, B., Concannon, P., Erlich, H. A., Julier, C., Morahan, G., Nerup, J., Nierras, C., Pociot, F. & Rich, S. S., Apr 2012, In : Diabetologia. 55, 4, p. 996-1000 5 p.

Research output: Contribution to journalArticle

31 Scopus citations

Confirmation of three susceptibility genes to insulin-dependent diabetes mellitus: IDDM4, IDDM5 and IDDM8

Luo, D. F., Buzzetti, R., Rotter, J. I., Maclaren, N. K., Raffel, L. J., Nisticò, L., Giovannini, C., Pozzilli, P., Thomson, G. & She, J-X., May 1996, In : Human Molecular Genetics. 5, 5, p. 693-698 6 p.

Research output: Contribution to journalArticle

134 Scopus citations

Construction of a physical and transcript map for a 1-Mb genomic region containing the urofacial (Ochoa) syndrome gene on 10q23-q24 and localization of the disease gene within two overlapping BAC clones (<360 kb)

Wang, C. Y., Shi, J. D., Huang, Y. Q., Cruz, P. E., Ochoa, B., Hawkins-Lee, B., Davoodi-Semiromi, A. & She, J. X., Aug 15 1999, In : Genomics. 60, 1, p. 12-19 8 p.

Research output: Contribution to journalArticle

18 Scopus citations

Co-occurrence of type 1 diabetes and celiac disease autoimmunity

Hagopian, W., Lee, H. S., Liu, E., Rewers, M., She, J. X., Ziegler, A. G., Lernmark, A., Toppari, J., Rich, S. S., Krischer, J. P., Erlich, H., Akolkar, B. & Agardh, D., Nov 2017, In : Pediatrics. 140, 5, e20171305.

Research output: Contribution to journalArticle

25 Scopus citations

Co-targeting EGFR and survivin with a bivalent aptamer-dual siRNA chimera effectively suppresses prostate cancer

Liu, H., Yu, X., Liu, H., Wu, D. & She, J-X., Jul 26 2016, In : Scientific reports. 6, 30346.

Research output: Contribution to journalArticle

31 Scopus citations

Country-specific birth weight and length in type 1 diabetes high-risk HLA genotypes in combination with prenatal characteristics

Sterner, Y., Törn, C., Lee, H. S., Larsson, H., Winkler, C., McLeod, W., Lynch, K., Simell, O., Ziegler, A., Schatz, D., Hagopian, W., Rewers, M., She, J. X., Krischer, J. P., Akolkar, B. & Lernmark, Å., Dec 2011, In : Journal of Perinatology. 31, 12, p. 764-769 6 p.

Research output: Contribution to journalArticle

6 Scopus citations

Cytokeratin-8 in anaplastic thyroid carcinoma: More than a simple structural cytoskeletal protein

Guo, D., Xu, Q., Pabla, S., Koomen, J., Biddinger, P. W., Sharma, A. K., Pabla, S., Pacholczyk, R. W., Chang, C. C., Friedrich, K., Mohammed, K., Smallridge, R. C., Copland, J. A., She, J-X. & Weinberger, P. M., Feb 14 2018, In : International journal of molecular sciences. 19, 2, 577.

Research output: Contribution to journalArticle

2 Scopus citations

Delineating the angiogenic gene expression profile before pulmonary vascular remodeling in a lamb model of congenital heart disease

Tian, J., Fratz, S., Hou, Y., Lu, Q., Görlach, A., Hess, J., Schreiber, C., Datar, S. A., Oishi, P., Nechtman, J., Podolsky, R., She, J. X., Fineman, J. R. & Black, S. M., Jan 2011, In : Physiological Genomics. 43, 2, p. 87-98 12 p.

Research output: Contribution to journalArticle

11 Scopus citations

Delineation of biological and molecular mechanisms underlying the diverse anticancer activities of mycophenolic acid

Dun, B., Xu, H., Sharma, A. K., Liu, H., Yu, H., Yi, B., Liu, X., He, M., Zeng, L. & She, J-X., Dec 5 2013, In : International Journal of Clinical and Experimental Pathology. 6, 12, p. 2880-2886 7 p.

Research output: Contribution to journalArticle

13 Scopus citations

Delineation of gastric cancer subtypes by co-regulated expression of receptor tyrosine kinases and chemosensitivity genes

Li, S. C., Ma, R., Wu, J. Z., Xiao, X., Wu, W., Li, G., Chen, B., Sharma, A. K., Bai, S., Dun, B. Y., She, J-X. & Tang, J. H., Sep 11 2015, In : American Journal of Translational Research. 7, 8, p. 1429-1439 11 p.

Research output: Contribution to journalArticle

8 Scopus citations

Depressive symptoms in mothers of infants identified as genetically at risk for type 1 diabetes

Hood, K. K., Johnson, S. B., Carmichael, S. K., Laffel, L. M. B., She, J-X. & Schatz, D. A., Aug 1 2005, In : Diabetes Care. 28, 8, p. 1898-1903 6 p.

Research output: Contribution to journalArticle

15 Scopus citations

Derivatives containing both coumarin and benzimidazole potently induce caspase-dependent apoptosis of cancer cells through inhibition of PI3K-AKT-mTOR signaling

Liu, H., Wang, Y., Sharma, A. K., Mao, R., Jiang, N., Dun, B. & She, J-X., Jun 9 2015, In : Anti-Cancer Drugs. 26, 6, p. 667-677 11 p.

Research output: Contribution to journalArticle

11 Scopus citations

Design, Synthesis, and in Vitro Evaluation of Novel 3, 7-Disubstituted Coumarin Derivatives as Potent Anticancer Agents

Wang, Y., Liu, H., Lu, P., Mao, R., Xue, X., Fan, C. & She, J., Oct 1 2015, In : Chemical Biology and Drug Design. 86, 4, p. 637-647 11 p.

Research output: Contribution to journalArticle

10 Scopus citations
13 Scopus citations

Detection of AIRE mutation in atypical autoimmune polyglandular syndrome type 1 (APS1)

Guttmann-Bauman, I., Shi, J. D., Wang, C. Y., She, J. X. & Guttmann-Bauman, I., Aug 23 2001, In : Journal of Endocrine Genetics. 2, 2, p. 115-121 7 p.

Research output: Contribution to journalArticle

1 Scopus citations

Detection of lactobacilli in monthly mail-in stool samples from 3-18 months old infants at genetic risk for type 1 diabetes

Salami, F., Abels, M., Hyöty, H., Vaziri-Sani, F., Aronsson, C. A., Vehik, K., Delli, A., Hagopian, W. A., Rewers, M., Ziegler, A. G., Simell, O., Akolkar, B., Krischer, J., She, J. & Leramark, Å., Dec 1 2012, In : International Journal of Probiotics and Prebiotics. 7, 3-4, p. 135-144 10 p.

Research output: Contribution to journalArticle

4 Scopus citations

Diagnostic and prognostic biomarker potential of kallikrein family genes in different cancer types

Tailor, P. D., Kodeboyina, S. K., Bai, S., Sharma, S., Ratnani, A., Copland, J. A., She, J-X., Sharma, A. K. & Patel, N., Apr 1 2018, In : Oncotarget. 9, 25, p. 17876-17888 13 p.

Research output: Contribution to journalArticle

10 Scopus citations

Dietary intake of soluble fiber and risk of islet autoimmunity by 5 y of age: Results from the TEDDY study

Beyerlein, A., Liu, X., Uusitalo, U. M., Harsunen, M., Norris, J. M., Foterek, K., Virtanen, S. M., Rewers, M. J., She, J. X., Simell, O., Lernmark, A., Hagopian, W., Akolkar, B., Ziegler, A. G., Krischer, J. P. & Hummel, S., Aug 1 2015, In : American Journal of Clinical Nutrition. 102, 2, p. 345-352 8 p.

Research output: Contribution to journalArticle

12 Scopus citations

Differences in recruitment and early retention among ethnic minority participants in a large pediatric cohort: The TEDDY Study

Baxter, J., Vehik, K., Johnson, S. B., Lernmark, B., Roth, R., Simell, T., Rewers, M., Barriga, K., Bautista, K., Baxter, J., Eisenbarth, G., Frank, N., Gesualdo, P., Hoffman, M., Ide, L., Karban, R., Liu, E., Norris, J., Waugh, K., Samper-Imaz, A. & 149 others, Steck, A., She, J-X., Schatz, D., Hopkins, D., Steed, L., Thomas, J., Silvis, K., Haller, M., Shankar, M., English, K., McIndoe, R. A., Liu, H., Nechtman, J., Williams, J., Foghis, G., Stephen, W., Anderson, M. D., Ziegler, A. G., Achenbach, A., Boerschmann, H., Bonifacio, E., Bunk, M., Försch, J., Henneberger, L., Hummel, M., Hummel, S., Joslowski, G., Kersting, M., Knopff, A., Kocher, N., Koletzko, S., Krause, S., Mann, A., Matzke, C., Mittermeier, A., Peplow, C., Pflüger, M., Ramminger, C., Strauss, E., Rash-Sur, S., Roth, R., Schenkel, J., Stock, J., Voit, K., Winkler, C., Wosch, A., Zwilling, M., Simell, O. G., Nanto-Salonen, K., Ilonen, J., Knip, M., Tuula Simell, V., Hyöty, H., Virtanen, S. M., Kronberg-Kippilä, C., Sjöberg, M., Simell, B., Ruohonen, E., Romo, M., Mantymaki, E., Schroderus, H., Nyblom, M., Stenius, A., Lernmark, Å., Agardh, D., Almgren, P., Andersson, E., Andrén-Aronsson, C., Ask, M., Karlsson, U. M., Cilio, C., Bremer, J., Ericson-Hallström, E., Gard, T., Gerardsson, J., Hansson, G., Hansen, M., Hyberg, S., Håkansson, R., Johansen, F., Jonsson, L., Larsson, H., Lernmark, B., Markan, M., Massadakis, T., Melin, J., Månsson-Martinez, M., Nilsson, A., Rahmati, K., Järvirova, M. S., Sibthorpe, S., Sjöberg, B., Skogberg, A., Törn, C., Wallin, A., Wimar, Å., Åberg, S., Hagopian, W. A., Yan, X., Killian, M., Cowen Crouch, C., Hay, K. M., Ayres, S., Adams, C., Bratrude, B., Coughlin, D., Fowler, G., Franco, C., Hammar, C., Heaney, D., Marcus, P., Meyer, A., Mulenga, D., Scott, E., Skidmore, J., Stabbert, J., Stepitova, V., Williams, N., Becker, D., Franciscus, M., Dalmagro-Elias, M. E., Daftary, A., Krischer, J. P., Abbondondolo, M., Ballard, L., Brown, R., Burkhardt, B., Cuthbertson, D., Eberhard, C., Fiske, S., Gowda, V., Hadley, D., Lee, H. S., Liu, S., Lynch, K., Malloy, J., McCarthy, C., McLeod, W., Smith, L., Smith, S., Uusitalo, U., Vehik, K., Washington, E., Yang, J., Akolkar, B., Briese, T., Erlich, H., Johnson, S. B. & Oberste, S., Jul 2012, In : Contemporary Clinical Trials. 33, 4, p. 633-640 8 p.

Research output: Contribution to journalArticle

25 Scopus citations
28 Scopus citations
26 Scopus citations

Discovery and validation of serum protein changes in type 1 diabetes patients using high throughput two dimensional liquid chromatography-mass spectrometry and immunoassays.

Zhi, W., Sharma, A., Purohit, S., Miller, E., Bode, B., Anderson, S. W., Reed, J. C., Steed, R. D., Steed, L., Hopkins, D. & She, J. X., Nov 1 2011, In : Molecular & cellular proteomics : MCP. 10, 11

Research output: Contribution to journalArticle

41 Scopus citations

Disordered osteoclast formation in RAGE-deficient mouse establishes an essential role for RAGE in diabetes related bone loss

Ding, K., Wang, Z. Z., Hamrick, M. W., Deng, Z. B., Zhou, L., Kang, B., Yan, S. L., She, J-X., Stern, D. M., Isales, C. M. & Mi, Q. S., Feb 24 2006, In : Biochemical and Biophysical Research Communications. 340, 4, p. 1091-1097 7 p.

Research output: Contribution to journalArticle

88 Scopus citations

Distinct growth phases in early life associated with the risk of type 1 diabetes: The teddy study

TEDDY study group, Mar 1 2020, In : Diabetes Care. 43, 3, p. 556-562 7 p.

Research output: Contribution to journalArticle

Early childhood gut microbiomes show strong geographic differences among subjects at high risk for type 1 diabetes

Kemppainen, K. M., Ardissone, A. N., Davis-Richardson, A. G., Fagen, J. R., Gano, K. A., León-Novelo, L. G., Vehik, K., Casella, G., Simell, O., Ziegler, A. G., Rewers, M. J., Lernmark, Å., Hagopian, W., She, J. X., Krischer, J. P., Akolkar, B., Schatz, D. A., Atkinson, M. A. & Triplett, E. W., Feb 1 2015, In : Diabetes Care. 38, 2, p. 329-332 4 p.

Research output: Contribution to journalArticle

47 Scopus citations

Early Diagnosis and Specific Treatment of Insulin‐Dependent Diabetes

MACLAREN, NOEL., MUIR, ANDREW., SILVERSTEIN, JANET., SONG, YAOHUA. H., SHE, JIN. XIONG., KRISCHER, JEFFREY., ATKINSON, MARK. & SCHATZ, DESMOND., Jan 1 1993, In : Annals of the New York Academy of Sciences. 696, 1, p. 342-350 9 p.

Research output: Contribution to journalArticle

Early infant diet and islet autoimmunity in the TEDDY study

Uusitalo, U., Lee, H. S., Aronsson, C. A., Vehik, K., Yang, J., Hummel, S., Silvis, K., Lernmark, Å., Rewers, M., Hagopian, W., She, J. X., Simell, O., Toppari, J., Ziegler, A. G., Akolkar, B., Krischer, J., Virtanen, S. M. & Norris, J. M., Mar 1 2018, In : Diabetes Care. 41, 3, p. 522-530 9 p.

Research output: Contribution to journalArticle

24 Scopus citations

Early pathogenic events associated with Sjögren's syndrome (SjS)-like disease of the nod mouse using microarray analysis

Killedar, S. Y., Eckenrode, S. E., McIndoe, R. A., She, J. X., Nguyen, C. Q., Peck, A. B. & Cha, S. R., Dec 2 2006, In : Laboratory Investigation. 86, 12, p. 1243-1260 18 p.

Research output: Contribution to journalArticle

46 Scopus citations

Early probiotic supplementation and the risk of celiac disease in children at genetic risk

TEDDY study group, Aug 2019, In : Nutrients. 11, 8, 1790.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Effect of PPARγ inhibition on pulmonary endothelial cell gene expression: Gene profiling in pulmonary hypertension

Tian, J., Smith, A., Nechtman, J., Podolsky, R., Aggarwal, S., Snead, C., Kumar, S., Elgaish, M., Oishi, P., Göerlach, A., Fratz, S., Hess, J., Catravas, J. D., Verin, A. D., Fineman, J. R., She, J. X. & Black, S. M., Jan 2009, In : Physiological Genomics. 40, 1, p. 48-60 13 p.

Research output: Contribution to journalArticle

35 Scopus citations
19 Scopus citations

Enhanced T Cell Lymphoma in NOD.Stat5b Transgenic Mice Is Caused by Hyperactivation of Stat5b in CD8+ Thymocytes

Chen, B., Yi, B., Mao, R., Liu, H., Wang, J., Sharma, A., Peiper, S., Leonard, W. J. & She, J. X., Feb 14 2013, In : PloS one. 8, 2, e56600.

Research output: Contribution to journalArticle

6 Scopus citations

Erbb3-mediated regulation of bergmann glia proliferation in cerebellar lamination

Sathyamurthy, A., Yin, D. M., Barik, A., Shen, C., Bean, J. C., Figueiredo, D., She, J. X., Xiong, W. C. & Mei, L., Feb 1 2015, In : Development (Cambridge). 142, 3, p. 522-532 11 p.

Research output: Contribution to journalArticle

14 Scopus citations

Evidence of gene-gene interaction and age-at-diagnosis effects in type 1 diabetes

Howson, J. M. M., Cooper, J. D., Smyth, D. J., Walker, N. M., Stevens, H., She, J. X., Eisenbarth, G. S., Rewers, M., Todd, J. A., Akolkar, B., Concannon, P., Erlich, H. A., Julier, C., Morahan, G., Nerup, J., Nierras, C., Pociot, F. & Rich, S. S., Nov 2012, In : Diabetes. 61, 11, p. 3012-3017 6 p.

Research output: Contribution to journalArticle

46 Scopus citations

Evolutionary origins of retroposon lineages of Mhc class II Ab alleles

Lu, C. C., Ye, Y., She, J-X., Bonhomme, F. & Wakeland, E. K., May 1996, In : Immunogenetics. 43, 3, p. 115-124 10 p.

Research output: Contribution to journalArticle

3 Scopus citations

Expression and alternative splicing of the mouse autoimmune regulator gene (Aire)

Ruan, Q. G., Wang, C. Y., Shi, J. D. & She, J-X., Jan 1 1999, In : Journal of Autoimmunity. 13, 3, p. 307-313 7 p.

Research output: Contribution to journalArticle

32 Scopus citations

Extracellular high-mobility group box 1 acts as an innate immune mediator to enhance autoimmune progression and diabetes onset in NOD mice

Han, J., Zhong, J., Wei, W., Wang, Y., Huang, Y., Yang, P., Purohit, S. B., Dong, Z., Wang, M-H., She, J-X., Gong, F., Stern, D. M. & Wang, C. Y., Aug 2008, In : Diabetes. 57, 8, p. 2118-2127 10 p.

Research output: Contribution to journalArticle

86 Scopus citations

Factors associated with longitudinal food record compliance in a paediatric cohort study

Yang, J., Lynch, K. F., Uusitalo, U. M., Foterek, K., Hummel, S., Silvis, K., Andrén Aronsson, C., Riikonen, A., Rewers, M., She, J-X., Ziegler, A. G., Simell, O. G., Toppari, J., Hagopian, W. A., Lernmark, Å., Akolkar, B., Krischer, J. P., Norris, J. M., Virtanen, S. M. & Johnson, S. B., Apr 1 2016, In : Public Health Nutrition. 19, 5, p. 804-813 10 p.

Research output: Contribution to journalArticle

3 Scopus citations

Factors That Increase Risk of Celiac Disease Autoimmunity After a Gastrointestinal Infection in Early Life

TEDDY study group, May 2017, In : Clinical Gastroenterology and Hepatology. 15, 5, p. 694-702.e5

Research output: Contribution to journalArticle

57 Scopus citations