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Research Output

2017

Respiratory infections are temporally associated with initiation of type 1 diabetes autoimmunity: the TEDDY study

On behalf of the TEDDY Study Group, Oct 1 2017, In : Diabetologia. 60, 10, p. 1931-1940 10 p.

Research output: Contribution to journalArticle

31 Scopus citations

The influence of type 1 diabetes genetic susceptibility regions, age, sex, and family history on the progression from multiple autoantibodies to type 1 diabetes: A teddy study report

Krischer, J. P., Liu, X., Lernmark, Å., Hagopian, W. A., Rewers, M. J., She, J. X., Toppari, J., Ziegler, A. G. & Akolkar, B., Dec 1 2017, In : Diabetes. 66, 12, p. 3122-3129 8 p.

Research output: Contribution to journalArticle

42 Scopus citations
2016
6 Scopus citations

Association of Early Exposure of Probiotics and Islet Autoimmunity in the TEDDY Study

Dietary Biomarkers Laboratory, Project Scientist, Other contributors, Autoantibody Reference Laboratories, Cortisol Laboratory, Data Coordinating Center, Pennsylvania Satellite Center, Washington Clinical Center, Sweden Clinical Center, Finland Clinical Center, Germany Clinical Center, Georgia/Florida Clinical Center, for the TEDDY Study Group, SNP Laboratory, RNA Laboratory and Gene Expression Laboratory, Microbiome and Viral Metagenomics Laboratory, Metabolomics Laboratory, HbA1c Laboratory, HLA Reference Laboratory, OGTT Laboratory & 2 others, Proteomics Laboratory & Repository, Jan 2016, In : JAMA Pediatrics. 170, 1, p. 20-28 9 p.

Research output: Contribution to journalArticle

101 Scopus citations

Characterization of immune response to novel HLA-A2-restricted epitopes from zinc transporter 8 in type 1 diabetes

Xu, X., Gu, Y., Bian, L., Shi, Y., Cai, Y., Chen, Y., Chen, H., Qian, L., Wu, X., Xu, K., Mallone, R., Davidson, H. W., Yu, L., She, J-X., Zhang, M. & Yang, T., Feb 3 2016, In : Vaccine. 34, 6, p. 854-862 9 p.

Research output: Contribution to journalArticle

13 Scopus citations

Complement gene variants in relation to autoantibodies to beta cell specific antigens and type 1 diabetes in the TEDDY Study

Törn, C., Liu, X., Hagopian, W., Lernmark, Å., Simell, O., Rewers, M., Ziegler, A. G., Schatz, D., Akolkar, B., Onengut-Gumuscu, S., Chen, W. M., Toppari, J., Mykkänen, J., Ilonen, J., Rich, S. S., She, J-X., Sharma, A. K., Steck, A. & Krischer, J., Jun 16 2016, In : Scientific reports. 6, 27887.

Research output: Contribution to journalArticle

13 Scopus citations

Co-targeting EGFR and survivin with a bivalent aptamer-dual siRNA chimera effectively suppresses prostate cancer

Liu, H., Yu, X., Liu, H., Wu, D. & She, J-X., Jul 26 2016, In : Scientific reports. 6, 30346.

Research output: Contribution to journalArticle

29 Scopus citations

Factors associated with longitudinal food record compliance in a paediatric cohort study

Yang, J., Lynch, K. F., Uusitalo, U. M., Foterek, K., Hummel, S., Silvis, K., Andrén Aronsson, C., Riikonen, A., Rewers, M., She, J-X., Ziegler, A. G., Simell, O. G., Toppari, J., Hagopian, W. A., Lernmark, Å., Akolkar, B., Krischer, J. P., Norris, J. M., Virtanen, S. M. & Johnson, S. B., Apr 1 2016, In : Public Health Nutrition. 19, 5, p. 804-813 10 p.

Research output: Contribution to journalArticle

3 Scopus citations

Growth and risk for islet autoimmunity and progression to type 1 diabetes in early childhood: The environmental determinants of diabetes in the young study

Larsson, H. E., Vehik, K., Haller, M. J., Liu, X., Akolkar, B., Hagopian, W., Krischer, J., Lernmark, Å., She, J. X., Simell, O., Toppari, J., Ziegler, A. G. & Rewers, M., Jul 1 2016, In : Diabetes. 65, 7, p. 1988-1995 8 p.

Research output: Contribution to journalArticle

15 Scopus citations

Identification of non-HLA genes associated with celiac disease and country-specific differences in a large, international pediatric cohort

TEDDY study group, Mar 2016, In : PloS one. 11, 3, e0152476.

Research output: Contribution to journalArticle

20 Scopus citations

IGF-binding proteins in type-1 diabetes are more severely altered in the presence of complications

Sharma, A. K., Purohit, S. B., Sharma, S., Bai, S., Zhi, W., Ponny, S. R., Hopkins, D., Steed, L., Bode, B., Anderson, S. W. & She, J-X., Jan 1 2016, In : Frontiers in Endocrinology. 7, JAN, 2.

Research output: Contribution to journalArticle

8 Scopus citations

Reversion of β-cell autoimmunity changes risk of type 1 diabetes: TEDDY study

Vehik, K., Lynch, K. F., Schatz, D. A., Akolkar, B., Hagopian, W., Rewers, M., She, J. X., Simell, O., Toppari, J., Ziegle, A. G., Lernmark, A., Bonifacio, E. & Krischer, J. P., Sep 1 2016, In : Diabetes Care. 39, 9, p. 1535-1542 8 p.

Research output: Contribution to journalArticle

23 Scopus citations

The heterogeneity of islet autoantibodies and the progression of islet failure in type 1 diabetic patients

Liu, J., Bian, L., Ji, L., Chen, Y., Chen, H., Gu, Y., Ma, B., Gu, W., Xu, X., Shi, Y., Wang, J., Zhu, D., Sun, Z., Ma, J., Jin, H., Shi, X., Miao, H., Xin, B., Zhu, Y., Zhang, Z. & 52 others, Bu, R., Xu, L., Shi, G., Tang, W., Li, W., Zhou, D., Liang, J., Cheng, X., Shi, B., Dong, J., Hu, J., Fang, C., Zhong, S., Yu, W., Lu, W., Wu, C., Qian, L., Yu, J., Gao, J., Fei, X., Zhang, Q., Wang, X., Cui, S., Cheng, J., Xu, N., Wang, G., Han, G., Xu, C., Xie, Y., An, M., Zhang, W., Wang, Z., Cai, Y., Fu, Q., Fu, Y., Zheng, S., Yang, F., Hu, Q., Dai, H., Jin, Y., Zhang, Z., Xu, K., Li, Y., Shen, J., Zhou, H., He, W., Zheng, X., Han, X., Yu, L., She, J-X., Zhang, M. & Yang, T., Sep 1 2016, In : Science China Life Sciences. 59, 9, p. 930-939 10 p.

Research output: Contribution to journalArticle

5 Scopus citations

Tumor profiling of co-regulated receptor tyrosine kinase and chemoresistant genes reveal different targeting options for lung and gastroesophageal cancers

Wu, J., Li, S., Ma, R., Sharma, A. K., Bai, S., Dun, B., Cao, H., Jing, C., She, J-X. & Feng, J., Jan 1 2016, In : American Journal of Translational Research. 8, 12, p. 5729-5740 12 p.

Research output: Contribution to journalArticle

4 Scopus citations
2015

3D-QSAR based pharmacophore modeling and virtual screening for identification of novel G protein-coupled receptor40 agonists

Lu, P., Wang, Y., Ouyang, P. K., She, J. & He, M., Jul 1 2015, In : Current Computer-Aided Drug Design. 11, 1, p. 51-56 6 p.

Research output: Contribution to journalArticle

3 Scopus citations

Age at gluten introduction and risk of celiac disease

TEDDY study group, Feb 1 2015, In : Pediatrics. 135, 2, p. 239-245 7 p.

Research output: Contribution to journalArticle

76 Scopus citations

A method for reporting and classifying acute infectious diseases in a prospective study of young children: TEDDY

Lönnrot, M., Lynch, K., Larsson, H. E., Lernmark, Å., Rewers, M., Hagopian, W., She, J. X., Simell, O., Ziegler, A. G., Akolkar, B., Krischer, J. & Hyöty, H., Mar 20 2015, In : BMC pediatrics. 15, 1, 24.

Research output: Contribution to journalArticle

15 Scopus citations

Delineation of gastric cancer subtypes by co-regulated expression of receptor tyrosine kinases and chemosensitivity genes

Li, S. C., Ma, R., Wu, J. Z., Xiao, X., Wu, W., Li, G., Chen, B., Sharma, A. K., Bai, S., Dun, B. Y., She, J-X. & Tang, J. H., Sep 11 2015, In : American Journal of Translational Research. 7, 8, p. 1429-1439 11 p.

Research output: Contribution to journalArticle

8 Scopus citations

Derivatives containing both coumarin and benzimidazole potently induce caspase-dependent apoptosis of cancer cells through inhibition of PI3K-AKT-mTOR signaling

Liu, H., Wang, Y., Sharma, A. K., Mao, R., Jiang, N., Dun, B. & She, J-X., Jun 9 2015, In : Anti-Cancer Drugs. 26, 6, p. 667-677 11 p.

Research output: Contribution to journalArticle

11 Scopus citations

Design, Synthesis, and in Vitro Evaluation of Novel 3, 7-Disubstituted Coumarin Derivatives as Potent Anticancer Agents

Wang, Y., Liu, H., Lu, P., Mao, R., Xue, X., Fan, C. & She, J., Oct 1 2015, In : Chemical Biology and Drug Design. 86, 4, p. 637-647 11 p.

Research output: Contribution to journalArticle

10 Scopus citations

Dietary intake of soluble fiber and risk of islet autoimmunity by 5 y of age: Results from the TEDDY study

Beyerlein, A., Liu, X., Uusitalo, U. M., Harsunen, M., Norris, J. M., Foterek, K., Virtanen, S. M., Rewers, M. J., She, J. X., Simell, O., Lernmark, A., Hagopian, W., Akolkar, B., Ziegler, A. G., Krischer, J. P. & Hummel, S., Aug 1 2015, In : American Journal of Clinical Nutrition. 102, 2, p. 345-352 8 p.

Research output: Contribution to journalArticle

12 Scopus citations

Early childhood gut microbiomes show strong geographic differences among subjects at high risk for type 1 diabetes

Kemppainen, K. M., Ardissone, A. N., Davis-Richardson, A. G., Fagen, J. R., Gano, K. A., León-Novelo, L. G., Vehik, K., Casella, G., Simell, O., Ziegler, A. G., Rewers, M. J., Lernmark, Å., Hagopian, W., She, J. X., Krischer, J. P., Akolkar, B., Schatz, D. A., Atkinson, M. A. & Triplett, E. W., Feb 1 2015, In : Diabetes Care. 38, 2, p. 329-332 4 p.

Research output: Contribution to journalArticle

47 Scopus citations
16 Scopus citations

Erbb3-mediated regulation of bergmann glia proliferation in cerebellar lamination

Sathyamurthy, A., Yin, D. M., Barik, A., Shen, C., Bean, J. C., Figueiredo, D., She, J. X., Xiong, W. C. & Mei, L., Feb 1 2015, In : Development (Cambridge). 142, 3, p. 522-532 11 p.

Research output: Contribution to journalArticle

14 Scopus citations

Fine mapping of type 1 diabetes susceptibility loci and evidence for colocalization of causal variants with lymphoid gene enhancers

Onengut-Gumuscu, S., Chen, W. M., Burren, O., Cooper, N. J., Quinlan, A. R., Mychaleckyj, J. C., Farber, E., Bonnie, J. K., Szpak, M., Schofield, E., Achuthan, P., Guo, H., Fortune, M. D., Stevens, H., Walker, N. M., Ward, L. D., Kundaje, A., Kellis, M., Daly, M. J., Barrett, J. C. & 419 others, Cooper, J. D., Deloukas, P., Todd, J. A., Wallace, C., Concannon, P., Rich, S. S., Baskerville, T., Bautista, N., Bhatia, E., Bhatia, V., Hasan, K. B., Bonnici, F., Brodnicki, T., Browning, B., Cameron, F., Chaichanwatanakul, K., Cheung, P. T., Colman, P., Cotterill, A., Couper, J., Crock, P., Cutfield, R., Davis, T., Dixon, P., Donaghue, K., Dowling, K., Drury, P., Dye, S., Gellert, S., Ghani, R. A., Greer, R., Han, X., Harrison, L., Homatopoulos, N., Ji, L., Jones, T., Yin, L. K., Kamaruddin, N. A., Kanga, U., Kanungo, A., Kaur, G., Kek, B., Knowles, S., Krebs, J., Kumar, N., Lee, Y. J., Li, X., Liktimaskul, S., Lloyd, M., Loth, A., Louey, A., Mehra, N., Merriman, T., Min, L., Morahan, G., Moses, R., Mraz, G., Murphy, R., Nicholson, I., Panelo, A., Poh, P., Price, G., Ratnam, N., Sanjeevi, C., Sedimbi, S., Shen, S., Ying, G. S., Tait, B., Tandon, N., Thomas, A., Varney, M., Weerakulwattana, P., Willis, J., Akwo, E. A., Albret, L., Ampudia-Blasco, F., Argente, J., Avbelj, M., Babadjanova, G., Badenhoop, K., Battelino, T., Beilhack, G., Bergholdt, R., Bingley, P., Boehm, B., Bolidson, J., Brismar, K., Brorsson, C., Carlson, J., Castano, L., Chandler, K., Cherubini, V., Cinek, O., Cipponeri, E., Collado, R. C., de Leiva, A., Dzivite, I., Fagulha, A., Balcells, M. F., Cuartero, B. G., Lacalle, C. G., Guja, C., Gutiérrez, P., Hamou, A., Hatziagelaki, E., Heath, S., Heilman, K., Helmberg, W., Hermon, O., Hernandez, M., Holzheu, I., Hosszufalusi, N., Ilonen, J., Ionescu-Tirgoviste, C., Johannesen, J., Julier, C., Kahles, H., Kinalska, I., Knip, M., Kockum, I., Kojo, E., Kordonouri, O., Kretowski, A., Krikovszky, D., Kurkhaus, A., Kuzmicki, M., Lavant, E., Long, A., Ludvigsson, J., Madacsy, L., Maliszewska, K., Marga, M., Martinez, M. P., Mauricio, D., Mazurkievicz, G., Nerup, J., Norkus, A., Mogollon, F. J. N., Okruszko, A., Pettinari, C., Phillip, M., Pirags, V., Pociot, F., Pozzilli, P., Racasan, R., Raile, K., Rappner, R., Troyano, M. J. R., Roep, B. O., Rokni, S., Rosinger, S., Rubio-Cabezas, O., Ruckgaber, C., Satman, I., Schober, E., Seufert, J., Sing, R., Skrha, J., Sobngwi, E., Somerville, M., Spinas, G., Sumnik, Z., Tilmann, V., Undlien, D., Urbanavicius, V., der Auwera, B. V., San Miguel, F. V., Vazeo-Gerasimidi, A., Velickiene, D., Wägner, A., Walter, M., Williams, A., Ziegler, A., Agleham, M., Aldrich, A., Alemzadeh, R., Alper, C., Aly, T., Anastassiou, D., Arora, S., Austin, A., Becker, D., Benoist, C., Berka, N., Bhatia, S., Bonella, P., Bottini, N., Boyle, S., Braden, J., Brady, B., Brickman, W., Christensen, R., Couch, R., Counts, D., Crandall, J., Daniels, M., Dolan, L., Donaldson, D., Doria, A., Eisenbarth, G., Elder, J., El-Hajj, R., Erlich, H., Fain, P., Fear, A. L., Ferry, R., Fiallo-Scharer, R., Geraghty, D., Ghosh, S., Gitelman, S., Godwin, M., Goland, R., Goodman, N., Goodwin, G., Gravely, J., Greenbaum, C., Gudgeon, C., Gunville, F., Hagopian, W., Hakonarson, H., Hansen, J., Harrington, K., Hassing, J., Hilliker, W., Hoffman, R., Hulbert, E., Izquierdo, R., Jospe, N., Kaiserman, K., Kaufman, F., Kim, S., Kloos, E., Kosoy, R., Lane, J., Lane, J., Lawrence, J., Levetan, C., Levin, P., Lipton, R., Lonsdale, J., Magnuson, V., Marks, J., Mayer-Davis, B., McEvoy, R., McIndoe, R., Merkle, L., Metzger, D., Miao, D., Mickelson, E., Moonsamy, P., Moore, W., Moran, A., Noble, J., Olsem, G., Orban, T., Orlowski, C., Paterson, A., Pietropaolo, M., Pihoker, C., Polychronakos, C., Post, J., Postellon, D., Pugliese, A., Qu, H. Q., Quattrin, T., Rappaport, M., Raskin, P., Risbeck, H., Rodriguez, H., Rodriguez, L., Rogers, M., Rubalcava, L., Russell, B., Schatz, D., Scott, C., She, J-X., Shilling, H., Shulman, D., Soyka, L., Speiser, P., Starkman, H., Steck, A., Stender, S., Stratton, L., Sur, D., Taback, S., Thrailkill, K., Toth, E., Trymbiski, P., Tsalikian, E., Vertachnik, K., Wahlen, J., Wang, X., Weber, S., Wherrett, D., Willi, S., Wilson, D., Youkey, J., Young, N., Yu, L., Zhao, L. P., Zimmerman, D., Adlem, E., Allen, J., Brown, J., Clarke, P., Clayton, D., Coleman, G., Cucca, F., Davison, L., Downes, K., Duley, S., Dunger, D., Esposito, L., Everett, V., Field, S., Hafler, J., Hardy, M., Harrison, D., Harrison, I., Hawkins, S., Healy, B., Hood, S., Howell, S., Howson, J., Maisuria, M., Meadows, W., Mistry, T., Nezhenstsev, S., Nutland, S., Ovington, N., Plagnol, V., Rainbow, D., Rainbow, K., Raj, S., Schuilenburg, H., Simpson, A., Smink, L., Smyth, D., Taylor, N., Tuomilehto, J., Wicker, L., Widmer, B., Wilson, M., Withers, H., Yang, J., Brown, M., Crews, A., Griffin, J., Hall, M., Harnish, T., Hepler, J., Hilner, J., King, N., Lohman, K., Lu, L., Nail, J., Perdue, L., Pierce, J., Reboussin, D., Rushing, S., Sale, M., Sides, E., Snively, B., Teuschler, H., Theil, G., Wagenknecht, L., Williams, D., Akolkar, B., McKeon, C., Nierras, C., Thomson, E., Altshuler, D., Au, K., Bain, S., Barcellos, L., Barral, S., Becker, T., Briggs, F., Bronson, P., de Bakker, P., Devlin, B., Eike, M. C., Field, L., Gabriel, S., Garge, N., Gaudieri, S., Goldstein, B., Gorodezky, C., Hamon, S., He, C., Howson, J., Humphreys, K., James, I., Lathrop, M., Lie, B. A., Li, D., Mack, S., McGinnis, R., McKinnon, E., McLaren, W., Nolan, D., Olsson, M., Ott, J., Owerbach, D., Patterson, C., Podolsky, R., Ramsay, P., Rangantah, V., Risch, N., Ronningen, K. S., Shao, X., Single, R., Steffes, M., Thomson, G., Valdes, A. M., Vandiedonck, C., Whittaker, P. & Zhang, Q., Apr 28 2015, In : Nature Genetics. 47, 4, p. 381-386 6 p.

Research output: Contribution to journalArticle

236 Scopus citations

HLA-DPB1∗04:01 protects genetically susceptible children from celiac disease autoimmunity in the TEDDY study

Hadley, D., Hagopian, W., Liu, E., She, J-X., Simell, O., Akolkar, B., Ziegler, A. G., Rewers, M., Krischer, J. P., Chen, W. M., Onengut-Gumuscu, S., Bugawan, T. L., Rich, S. S., Erlich, H. & Agardh, D., Jun 10 2015, In : American Journal of Gastroenterology. 110, 6, p. 915-920 6 p.

Research output: Contribution to journalArticle

14 Scopus citations

Inflammatory serum proteins are severely altered in metastatic gastric adenocarcinoma patients from the Chinese population

Wang, J., Ma, R., Sharma, A. K., He, M., Xue, J., Wu, J., Dun, B., Li, G., Wang, X., Ji, M., She, J-X. & Tang, J., Apr 17 2015, In : PloS one. 10, 4, e0123985.

Research output: Contribution to journalArticle

7 Scopus citations

Large-scale discovery and validation studies demonstrate significant reductions in circulating levels of IL8, IL-1Ra, MCP-1, and MIP-1β in patients with type 1 diabetes

Purohit, S. B., Sharma, A. K., Hopkins, D., Steed, L., Bode, B., Anderson, S. W., Reed, J. C., Steed, R. D., Yang, T. & She, J-X., Sep 1 2015, In : Journal of Clinical Endocrinology and Metabolism. 100, 9, p. E1179-E1187

Research output: Contribution to journalArticle

8 Scopus citations
9 Scopus citations

Maternal anxiety about a child's diabetes risk in the TEDDY study: The potential role of life stress, postpartum depression, and risk perception

TEDDY study group, Jun 1 2015, In : Pediatric Diabetes. 16, 4, p. 287-298 12 p.

Research output: Contribution to journalArticle

10 Scopus citations
70 Scopus citations

Role of type 1 diabetes- Associated snps on risk of autoantibody positivity in the TEDDY study

Törn, C., Hadley, D., Lee, H. S., Hagopian, W., Lernmark, Å., Simell, O., Rewers, M., Ziegler, A., Schatz, D., Akolkar, B., Onengut-Gumuscu, S., Chen, W. M., Toppari, J., Mykkänen, J., Ilonen, J., Rich, S. S., She, J-X., Steck, A. K. & Krischer, J., May 2015, In : Diabetes. 64, 5, p. 1818-1829 12 p.

Research output: Contribution to journalArticle

56 Scopus citations

The 6 year incidence of diabetes-associated autoantibodies in genetically at-risk children: the TEDDY study

Krischer, J. P., Lynch, K. F., Schatz, D. A., Ilonen, J., Lernmark, Å., Hagopian, W. A., Rewers, M. J., She, J. X., Simell, O. G., Toppari, J., Ziegler, A. G., Akolkar, B. & Bonifacio, E., May 1 2015, In : Diabetologia. 58, 5, p. 980-987 8 p.

Research output: Contribution to journalArticle

157 Scopus citations
2014

A novel monoclonal antibody induces cancer cell apoptosis and enhances the activity of chemotherapeutic drugs

Xu, H., Tian, Y. N., Dun, B. Y., Liu, H. T., Dong, G. K., Wang, J. H., Lu, S. S., Chen, B. & She, J. X., 2014, In : Asian Pacific Journal of Cancer Prevention. 15, 11, p. 4423-4428 6 p.

Research output: Contribution to journalArticle

4 Scopus citations

Anti-angiogenic effect of auranofin on HUVECs in vitro and zebrafish in vivo

He, M. F., Gao, X. P., Li, S. C., He, Z. H., Chen, N., Wang, Y. B. & She, J. X., Jan 1 2014, In : European Journal of Pharmacology. 740, p. 240-247 8 p.

Research output: Contribution to journalArticle

15 Scopus citations

Biomarker discovery study design for type 1 diabetes in The Environmental Determinants of Diabetes in the Young (TEDDY) study

Lee, H. S., Burkhardt, B. R., Mcleod, W., Smith, S., Eberhard, C., Lynch, K., Hadley, D., Rewers, M., Simell, O., She, J. X., Hagopian, B., Lernmark, A., Akolkar, B., Ziegler, A. G., Krischer, J. P., Barriga, K., Bautista, K., Baxter, J., Eisenbarth, G., Frank, N. & 208 others, Gesualdo, P., Hoffman, M., Ide, L., Karban, R., Liu, E., Norris, J., Waugh, K., Samper-Imaz, A., Steck, A., Schatz, D., Hopkins, D., Steed, L., Thomas, J., Silvis, K., Haller, M., Shankar, M., Sheehan, E., Gardiner, M., McIndoe, R., Liu, H., Nechtman, J., Sharma, A., Williams, J., Foghis, G., Anderson W., S. W., Beyerlein, A., Bonifacio, E., Hummel, M., Hummel, S., Foterek, K., Kersting, M., Knopff, A., Koletzko, S., Peplow, C., Roth, R., Schenke, J., Stock, J., Strauss, E., Warncke, K., Winkler, C., Simell G., O. G., Hyoty, H., Ilonen, J., Knip, M., Koivu, A., Koreasalo, M., Kahonen, M., Lonnrot, M., Multasuo, K., Mantymaki, E., Mykkanen, J., Nanto-Salonen, K., Niininen, T., Nyblom, M., Rautanen, J., Riikonen, A., Romo, M., Simell, A., Simell, B., Simell, T., Simell, V., Sjoberg, M., Stenius, A., Toppari, J., Varjonen, E., Veijola, R., Virtanen M., S. M., Akerlund, M., Agardh, D., Andrén-Aronsson, C., Ask, M., Bremer, J., Carlsson, U. M., Cilio, C., Ericson-Hallstrom, E., Fransson, L., Gard, T., Gerardsson, J., Hakansson, R., Hansen, M., Hansson, G., Hyberg, S., Johansen, F., Jonasdottir, B., Jonsson, L., Larsson, H., Lernmark, B., Mansson-Martinez, M., Markan, M., Massadakis, T., Melin, J., Mestan, Z., Nilsson, A., Nilsson, E., Rahmati, K., Rosenquist, A., Salami, F., Jarvirova, M. S., Sibthorpe, S., Sjoberg, B., Swartling, U., Trulsson, E., Torn, C., Wallin, A., Wimar, A., Aberg, S., Hagopian A., W. A., Yan, X., Killian, M., Crouch, C. C., Hay M., K. M., Ayres, S., Adams, C., Bratrude, B., Coughlin, D., Fowler, G., Franco, C., Hammar, C., Heaney, D., Marcus, P., Meyer, A., Mulenga, D., Scott, E., Skidmore, J., Stabbert, J., Stepitova, V., Williams, N., Becker, D., Franciscus, M., Dalmagro-Elias, M. E., Daftary, A., Klein, M. B., Abbondondolo, M., Austin-Gonzalez, S., Brown, R., Burkhardt, B., Butterworth, M., Cuthbertson, D., Eberhard, C., Fiske, S., Gowda, V., Lane, P., Liu, S., Liu, X., Malloy, J., McCarthy, C., McLeod, W., Smith, L., Tamura, R., Uusitalo, U., Vehik, K., Washington, E., Yang, J., Bourcier, K., Briese, T., Johnson, S. B., Oberste, S., Triplett, E., Yu, L., Miao, D., Bingley, P., Williams, A., Chandler, K., Rokni, S., Long, A., Boldison, J., Butterly, J., Broadhurst, J., Carreno, G., Curnock, R., Easton, P., Geoghan, I., Goode, J., Pearson, J., Reed, C., Ridewood, S., Wyatt, R., Eriksson, E. A., Karlsson, E. L., Erlund, I., Salminen, I., Sundvall, J., Leiviska, J., Lehtonen, M., Little R., R. R., Tennill L., A. L., Erlich, H., Bugawan, T., Alejandrino, M., Fiehn, O., Wikoff, B., Kind, T., Palazoglu, M., Wong, J., Wohlgemuth, G., Petrosino F., J. F., Marcovina M., S. M., Higgins, H., Ke, S., Zhao, Y., Jiang, N., Rich S., S. S., Chen, W. M., Onengut-Gumuscu, S., Farber, E., Pickin, R. R., Davis, J. & Gallo, D., Jul 2014, In : Diabetes/Metabolism Research and Reviews. 30, 5, p. 424-434 11 p.

Research output: Contribution to journalArticle

17 Scopus citations

Children followed in the TEDDY study are diagnosed with type 1 diabetes at an early stage of disease

Elding Larsson, H., Vehik, K., Gesualdo, P., Akolkar, B., Hagopian, W., Krischer, J., Lernmark, Å., Rewers, M., Simell, O., She, J. X., Ziegler, A. & Haller, M. J., Mar 2014, In : Pediatric Diabetes. 15, 2, p. 118-126 9 p.

Research output: Contribution to journalArticle

38 Scopus citations

Pharmacophore-based discovery of new human dihydroorotate dehydrogenase inhibitor

Lu, P., Wang, Y., Ma, B., She, J., Zhang, Q., He, M. & Liu, Y., Jun 2014, In : Medicinal Chemistry. 10, 4, p. 402-408 7 p.

Research output: Contribution to journalArticle

3 Scopus citations

Prevalence of obesity was related to HLA-DQ in 2-4-year-old children at genetic risk for type 1 diabetes

Yang, J., Lernmark, Uusitalo, U. M., Lynch, K. F., Veijola, R., Winkler, C., Larsson, H. E., Rewers, M., She, J. X., Ziegler, A. G., Simell, O. G., Hagopian, W. A., Akolkar, B., Krischer, J. P. & Vehik, K., Dec 11 2014, In : International Journal of Obesity. 38, 12, p. 1491-1496 6 p.

Research output: Contribution to journalArticle

9 Scopus citations
21 Scopus citations

Serum Dickkopf-1 (DKK1) is significantly lower in patients with lung cancer but is rapidly normalized after treatment

Xu, H., Wu, J., Chen, B., Li, M., Tian, Y., He, M., Xue, J., Wang, J., Bai, S., Sharma, A. K., Liu, H., Tang, J. & She, J-X., Jan 1 2014, In : American Journal of Translational Research. 6, 6, p. 850-856 7 p.

Research output: Contribution to journalArticle

15 Scopus citations
2 Scopus citations

Synthesis and in vitro evaluation of 1,3,4-thiadiazol-2-yl urea derivatives as novel AChE inhibitors

Xue, X. J., Wang, Y. B., Lu, P., Shang, H. F., She, J. X., Xia, L. X., Qian, H. & Huang, W. L., Jun 2014, In : Chemical and Pharmaceutical Bulletin. 62, 6, p. 524-527 4 p.

Research output: Contribution to journalArticle

5 Scopus citations

Toxicity assessment of 7 anticancer compounds in zebrafish

Gao, X. P., Feng, F., Zhang, X. Q., Liu, X. X., Wang, Y. B., She, J. X., He, Z. H. & He, M. F., Jan 1 2014, In : International Journal of Toxicology. 33, 2, p. 98-105 8 p.

Research output: Contribution to journalArticle

14 Scopus citations

Transcriptomic changes induced by mycophenolic acid in gastric cancer cells

Dun, B., Sharma, A., Xu, H., Liu, H., Bai, S., Zeng, L. & She, J. X., 2014, In : American Journal of Translational Research. 6, 1, p. 28-42 15 p.

Research output: Contribution to journalArticle

15 Scopus citations
12 Scopus citations
2013

Delineation of biological and molecular mechanisms underlying the diverse anticancer activities of mycophenolic acid

Dun, B., Xu, H., Sharma, A. K., Liu, H., Yu, H., Yi, B., Liu, X., He, M., Zeng, L. & She, J-X., Dec 5 2013, In : International Journal of Clinical and Experimental Pathology. 6, 12, p. 2880-2886 7 p.

Research output: Contribution to journalArticle

12 Scopus citations

Enhanced T Cell Lymphoma in NOD.Stat5b Transgenic Mice Is Caused by Hyperactivation of Stat5b in CD8+ Thymocytes

Chen, B., Yi, B., Mao, R., Liu, H., Wang, J., Sharma, A., Peiper, S., Leonard, W. J. & She, J. X., Feb 14 2013, In : PloS one. 8, 2, e56600.

Research output: Contribution to journalArticle

6 Scopus citations

Methods, quality control and specimen management in an international multicentre investigation of type 1 diabetes: TEDDY

Vehik, K., Fiske, S. W., Logan, C. A., Agardh, D., Cilio, C. M., Hagopian, W., Simell, O., Roivainen, M., She, J. X., Briese, T., Oikarinen, S., Hyoty, H., Ziegler, A. G., Rewers, M., Lernmark, A., Akolkar, B., Krischer, J. P. & Burkhardt, B. R., Oct 1 2013, In : Diabetes/Metabolism Research and Reviews. 29, 7, p. 557-567 11 p.

Research output: Contribution to journalArticle

31 Scopus citations

Mycophenolic acid inhibits migration and invasion of gastric cancer cells via multiple molecular pathways

Dun, B., Sharma, A., Teng, Y., Liu, H., Purohit, S., Xu, H., Zeng, L. & She, J. X., Nov 15 2013, In : PloS one. 8, 11, e81702.

Research output: Contribution to journalArticle

20 Scopus citations