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Research Output 1987 2020

2016
12 Citations (Scopus)

Characterization of immune response to novel HLA-A2-restricted epitopes from zinc transporter 8 in type 1 diabetes

Xu, X., Gu, Y., Bian, L., Shi, Y., Cai, Y., Chen, Y., Chen, H., Qian, L., Wu, X., Xu, K., Mallone, R., Davidson, H. W., Yu, L., She, J-X., Zhang, M. & Yang, T., Feb 3 2016, In : Vaccine. 34, 6, p. 854-862 9 p.

Research output: Contribution to journalArticle

HLA-A2 Antigen
insulin-dependent diabetes mellitus
Type 1 Diabetes Mellitus
epitopes
transporters
12 Citations (Scopus)

Complement gene variants in relation to autoantibodies to beta cell specific antigens and type 1 diabetes in the TEDDY Study

Törn, C., Liu, X., Hagopian, W., Lernmark, Å., Simell, O., Rewers, M., Ziegler, A. G., Schatz, D., Akolkar, B., Onengut-Gumuscu, S., Chen, W. M., Toppari, J., Mykkänen, J., Ilonen, J., Rich, S. S., She, J-X., Sharma, A. K., Steck, A. & Krischer, J., Jun 16 2016, In : Scientific Reports. 6, 27887.

Research output: Contribution to journalArticle

Type 1 Diabetes Mellitus
Autoantibodies
Single Nucleotide Polymorphism
Antigens
Genes
27 Citations (Scopus)

Co-targeting EGFR and survivin with a bivalent aptamer-dual siRNA chimera effectively suppresses prostate cancer

Liu, H., Yu, X., Liu, H., Wu, D. & She, J-X., Jul 26 2016, In : Scientific Reports. 6, 30346.

Research output: Contribution to journalArticle

Small Interfering RNA
Prostatic Neoplasms
Nucleotide Aptamers
Antibodies
Heterografts
3 Citations (Scopus)

Factors associated with longitudinal food record compliance in a paediatric cohort study

Yang, J., Lynch, K. F., Uusitalo, U. M., Foterek, K., Hummel, S., Silvis, K., Andrén Aronsson, C., Riikonen, A., Rewers, M., She, J-X., Ziegler, A. G., Simell, O. G., Toppari, J., Hagopian, W. A., Lernmark, Å., Akolkar, B., Krischer, J. P., Norris, J. M., Virtanen, S. M. & Johnson, S. B., Apr 1 2016, In : Public Health Nutrition. 19, 5, p. 804-813 10 p.

Research output: Contribution to journalArticle

Compliance
Cohort Studies
Pediatrics
Food
Ambulatory Care
13 Citations (Scopus)

Growth and risk for islet autoimmunity and progression to type 1 diabetes in early childhood: The environmental determinants of diabetes in the young study

Larsson, H. E., Vehik, K., Haller, M. J., Liu, X., Akolkar, B., Hagopian, W., Krischer, J., Lernmark, Å., She, J. X., Simell, O., Toppari, J., Ziegler, A. G. & Rewers, M., Jul 1 2016, In : Diabetes. 65, 7, p. 1988-1995 8 p.

Research output: Contribution to journalArticle

Autoimmunity
Type 1 Diabetes Mellitus
Weights and Measures
Growth
Body Size
17 Citations (Scopus)

Identification of Non-HLA Genes Associated with Celiac Disease and Country-Specific Differences in a Large, International Pediatric Cohort

TEDDY study group, Jan 1 2016, In : PloS one. 11, 3, p. e0152476

Research output: Contribution to journalArticle

Pediatrics
celiac disease
Celiac Disease
Genes
autoantibodies
6 Citations (Scopus)

IGF-binding proteins in type-1 diabetes are more severely altered in the presence of complications

Sharma, A. K., Purohit, S. B., Sharma, S., Bai, S., Zhi, W., Ponny, S. R., Hopkins, D., Steed, L., Bode, B., Anderson, S. W. & She, J-X., Jan 1 2016, In : Frontiers in Endocrinology. 7, JAN, 2.

Research output: Contribution to journalArticle

Insulin-Like Growth Factor Binding Protein 1
Type 1 Diabetes Mellitus
Diabetes Complications
Insulin-Like Growth Factor Binding Proteins
Insulin-Like Growth Factor Binding Protein 2
18 Citations (Scopus)

Reversion of β-cell autoimmunity changes risk of type 1 diabetes: TEDDY study

Vehik, K., Lynch, K. F., Schatz, D. A., Akolkar, B., Hagopian, W., Rewers, M., She, J. X., Simell, O., Toppari, J., Ziegle, A. G., Lernmark, A., Bonifacio, E. & Krischer, J. P., Sep 1 2016, In : Diabetes Care. 39, 9, p. 1535-1542 8 p.

Research output: Contribution to journalArticle

Autoimmunity
Type 1 Diabetes Mellitus
Autoantibodies
Insulin
Insulinoma
5 Citations (Scopus)

The heterogeneity of islet autoantibodies and the progression of islet failure in type 1 diabetic patients

Liu, J., Bian, L., Ji, L., Chen, Y., Chen, H., Gu, Y., Ma, B., Gu, W., Xu, X., Shi, Y., Wang, J., Zhu, D., Sun, Z., Ma, J., Jin, H., Shi, X., Miao, H., Xin, B., Zhu, Y., Zhang, Z. & 52 others, Bu, R., Xu, L., Shi, G., Tang, W., Li, W., Zhou, D., Liang, J., Cheng, X., Shi, B., Dong, J., Hu, J., Fang, C., Zhong, S., Yu, W., Lu, W., Wu, C., Qian, L., Yu, J., Gao, J., Fei, X., Zhang, Q., Wang, X., Cui, S., Cheng, J., Xu, N., Wang, G., Han, G., Xu, C., Xie, Y., An, M., Zhang, W., Wang, Z., Cai, Y., Fu, Q., Fu, Y., Zheng, S., Yang, F., Hu, Q., Dai, H., Jin, Y., Zhang, Z., Xu, K., Li, Y., Shen, J., Zhou, H., He, W., Zheng, X., Han, X., Yu, L., She, J-X., Zhang, M. & Yang, T., Sep 1 2016, In : Science China Life Sciences. 59, 9, p. 930-939 10 p.

Research output: Contribution to journalArticle

autoantibodies
diabetes
Autoantibodies
antigen
risk factor
3 Citations (Scopus)

Tumor profiling of co-regulated receptor tyrosine kinase and chemoresistant genes reveal different targeting options for lung and gastroesophageal cancers

Wu, J., Li, S., Ma, R., Sharma, A. K., Bai, S., Dun, B., Cao, H., Jing, C., She, J-X. & Feng, J., Jan 1 2016, In : American Journal of Translational Research. 8, 12, p. 5729-5740 12 p.

Research output: Contribution to journalArticle

Receptor Protein-Tyrosine Kinases
Tumors
Lung Neoplasms
Genes
Stomach Neoplasms
2015
3 Citations (Scopus)

3D-QSAR based pharmacophore modeling and virtual screening for identification of novel G protein-coupled receptor40 agonists

Lu, P., Wang, Y., Ouyang, P. K., She, J. & He, M., Jul 1 2015, In : Current Computer-Aided Drug Design. 11, 1, p. 51-56 6 p.

Research output: Contribution to journalArticle

Quantitative Structure-Activity Relationship
GTP-Binding Proteins
Random Allocation
Hydrogen
Databases
72 Citations (Scopus)

Age at gluten introduction and risk of celiac disease

TEDDY study group, Feb 1 2015, In : Pediatrics. 135, 2, p. 239-245 7 p.

Research output: Contribution to journalArticle

Glutens
Celiac Disease
Autoantibodies
Finland
Germany
15 Citations (Scopus)

A method for reporting and classifying acute infectious diseases in a prospective study of young children: TEDDY

Lönnrot, M., Lynch, K., Larsson, H. E., Lernmark, Å., Rewers, M., Hagopian, W., She, J. X., Simell, O., Ziegler, A. G., Akolkar, B., Krischer, J. & Hyöty, H., Mar 20 2015, In : BMC pediatrics. 15, 1, 24.

Research output: Contribution to journalArticle

International Classification of Diseases
Acute Disease
Communicable Diseases
Prospective Studies
Infection
7 Citations (Scopus)

Delineation of gastric cancer subtypes by co-regulated expression of receptor tyrosine kinases and chemosensitivity genes

Li, S. C., Ma, R., Wu, J. Z., Xiao, X., Wu, W., Li, G., Chen, B., Sharma, A. K., Bai, S., Dun, B. Y., She, J-X. & Tang, J. H., Sep 11 2015, In : American Journal of Translational Research. 7, 8, p. 1429-1439 11 p.

Research output: Contribution to journalArticle

Receptor Protein-Tyrosine Kinases
Stomach Neoplasms
Genes
Chemotherapy
Platelet-Derived Growth Factor beta Receptor
11 Citations (Scopus)

Derivatives containing both coumarin and benzimidazole potently induce caspase-dependent apoptosis of cancer cells through inhibition of PI3K-AKT-mTOR signaling

Liu, H., Wang, Y., Sharma, A. K., Mao, R., Jiang, N., Dun, B. & She, J-X., Jun 9 2015, In : Anti-Cancer Drugs. 26, 6, p. 667-677 11 p.

Research output: Contribution to journalArticle

Caspases
Phosphatidylinositol 3-Kinases
Apoptosis
Genes
Coumarins
10 Citations (Scopus)

Design, Synthesis, and in Vitro Evaluation of Novel 3, 7-Disubstituted Coumarin Derivatives as Potent Anticancer Agents

Wang, Y., Liu, H., Lu, P., Mao, R., Xue, X., Fan, C. & She, J., Oct 1 2015, In : Chemical Biology and Drug Design. 86, 4, p. 637-647 11 p.

Research output: Contribution to journalArticle

Coumarins
K562 Cells
Antineoplastic Agents
Cells
Cell Line
11 Citations (Scopus)

Dietary intake of soluble fiber and risk of islet autoimmunity by 5 y of age: Results from the TEDDY study

Beyerlein, A., Liu, X., Uusitalo, U. M., Harsunen, M., Norris, J. M., Foterek, K., Virtanen, S. M., Rewers, M. J., She, J. X., Simell, O., Lernmark, A., Hagopian, W., Akolkar, B., Ziegler, A. G., Krischer, J. P. & Hummel, S., Aug 1 2015, In : American Journal of Clinical Nutrition. 102, 2, p. 345-352 8 p.

Research output: Contribution to journalArticle

Autoimmunity
Type 1 Diabetes Mellitus
Autoantibodies
Dietary Fiber
Proportional Hazards Models
43 Citations (Scopus)

Early childhood gut microbiomes show strong geographic differences among subjects at high risk for type 1 diabetes

Kemppainen, K. M., Ardissone, A. N., Davis-Richardson, A. G., Fagen, J. R., Gano, K. A., León-Novelo, L. G., Vehik, K., Casella, G., Simell, O., Ziegler, A. G., Rewers, M. J., Lernmark, Å., Hagopian, W., She, J. X., Krischer, J. P., Akolkar, B., Schatz, D. A., Atkinson, M. A. & Triplett, E. W., Feb 1 2015, In : Diabetes Care. 38, 2, p. 329-332 4 p.

Research output: Contribution to journalArticle

Microbiota
Type 1 Diabetes Mellitus
Finland
Sweden
Dysbiosis
16 Citations (Scopus)
Tumor Necrosis Factor Receptors
Diabetic Retinopathy
Type 1 Diabetes Mellitus
Cytokine Receptor gp130
Serum
14 Citations (Scopus)

Erbb3-mediated regulation of bergmann glia proliferation in cerebellar lamination

Sathyamurthy, A., Yin, D. M., Barik, A., Shen, C., Bean, J. C., Figueiredo, D., She, J. X., Xiong, W. C. & Mei, L., Feb 1 2015, In : Development (Cambridge). 142, 3, p. 522-532 11 p.

Research output: Contribution to journalArticle

Neuroglia
Neurons
Purkinje Cells
Phenotype
Genes
12 Citations (Scopus)

HLA-DPB1∗04:01 protects genetically susceptible children from celiac disease autoimmunity in the TEDDY study

Hadley, D., Hagopian, W., Liu, E., She, J-X., Simell, O., Akolkar, B., Ziegler, A. G., Rewers, M., Krischer, J. P., Chen, W. M., Onengut-Gumuscu, S., Bugawan, T. L., Rich, S. S., Erlich, H. & Agardh, D., Jun 10 2015, In : American Journal of Gastroenterology. 110, 6, p. 915-920 6 p.

Research output: Contribution to journalArticle

Celiac Disease
HLA Antigens
Autoimmunity
Autoantibodies
Gene Frequency
7 Citations (Scopus)

Inflammatory serum proteins are severely altered in metastatic gastric adenocarcinoma patients from the Chinese population

Wang, J., Ma, R., Sharma, A. K., He, M., Xue, J., Wu, J., Dun, B., Li, G., Wang, X., Ji, M., She, J-X. & Tang, J., Apr 17 2015, In : PloS one. 10, 4, e0123985.

Research output: Contribution to journalArticle

adenocarcinoma
blood proteins
Blood Proteins
Stomach
stomach
6 Citations (Scopus)

Large-scale discovery and validation studies demonstrate significant reductions in circulating levels of IL8, IL-1Ra, MCP-1, and MIP-1β in patients with type 1 diabetes

Purohit, S. B., Sharma, A. K., Hopkins, D., Steed, L., Bode, B., Anderson, S. W., Reed, J. C., Steed, R. D., Yang, T. & She, J-X., Sep 1 2015, In : Journal of Clinical Endocrinology and Metabolism. 100, 9, p. E1179-E1187

Research output: Contribution to journalArticle

Interleukin 1 Receptor Antagonist Protein
Validation Studies
Medical problems
Type 1 Diabetes Mellitus
Interleukin-8
9 Citations (Scopus)
Medical problems
Type 1 Diabetes Mellitus
Throughput
Technology
Assays
9 Citations (Scopus)

Maternal anxiety about a child's diabetes risk in the TEDDY study: The potential role of life stress, postpartum depression, and risk perception

TEDDY study group, Jun 1 2015, In : Pediatric Diabetes. 16, 4, p. 287-298 12 p.

Research output: Contribution to journalArticle

Postpartum Depression
Psychological Stress
Anxiety
Mothers
Type 1 Diabetes Mellitus
66 Citations (Scopus)
Autoantibodies
Insulin
Type 1 Diabetes Mellitus
Class 8 Receptor-Like Protein Tyrosine Phosphatases
Life Tables
52 Citations (Scopus)

Role of type 1 diabetes- Associated snps on risk of autoantibody positivity in the TEDDY study

Törn, C., Hadley, D., Lee, H. S., Hagopian, W., Lernmark, Å., Simell, O., Rewers, M., Ziegler, A., Schatz, D., Akolkar, B., Onengut-Gumuscu, S., Chen, W. M., Toppari, J., Mykkänen, J., Ilonen, J., Rich, S. S., She, J-X., Steck, A. K. & Krischer, J., May 2015, In : Diabetes. 64, 5, p. 1818-1829 12 p.

Research output: Contribution to journalArticle

Type 1 Diabetes Mellitus
Autoantibodies
Single Nucleotide Polymorphism
Genotype
Genome-Wide Association Study
142 Citations (Scopus)

The 6 year incidence of diabetes-associated autoantibodies in genetically at-risk children: the TEDDY study

Krischer, J. P., Lynch, K. F., Schatz, D. A., Ilonen, J., Lernmark, Å., Hagopian, W. A., Rewers, M. J., She, J. X., Simell, O. G., Toppari, J., Ziegler, A. G., Akolkar, B. & Bonifacio, E., May 1 2015, In : Diabetologia. 58, 5, p. 980-987 8 p.

Research output: Contribution to journalArticle

Autoantibodies
Incidence
Glutamate Decarboxylase
HLA-DR Antigens
Genotype
2014
4 Citations (Scopus)

A novel monoclonal antibody induces cancer cell apoptosis and enhances the activity of chemotherapeutic drugs

Xu, H., Tian, Y. N., Dun, B. Y., Liu, H. T., Dong, G. K., Wang, J. H., Lu, S. S., Chen, B. & She, J. X., 2014, In : Asian Pacific Journal of Cancer Prevention. 15, 11, p. 4423-4428 6 p.

Research output: Contribution to journalArticle

Monoclonal Antibodies
Apoptosis
Carcinoma
Pharmaceutical Preparations
Neoplasms
14 Citations (Scopus)

Anti-angiogenic effect of auranofin on HUVECs in vitro and zebrafish in vivo

He, M. F., Gao, X. P., Li, S. C., He, Z. H., Chen, N., Wang, Y. B. & She, J. X., Jan 1 2014, In : European Journal of Pharmacology. 740, p. 240-247 8 p.

Research output: Contribution to journalArticle

Auranofin
Zebrafish
Vascular Endothelial Growth Factor A
Physiological Phenomena
Thioredoxin-Disulfide Reductase
16 Citations (Scopus)

Biomarker discovery study design for type 1 diabetes in The Environmental Determinants of Diabetes in the Young (TEDDY) study

Lee, H. S., Burkhardt, B. R., Mcleod, W., Smith, S., Eberhard, C., Lynch, K., Hadley, D., Rewers, M., Simell, O., She, J. X., Hagopian, B., Lernmark, A., Akolkar, B., Ziegler, A. G., Krischer, J. P., Barriga, K., Bautista, K., Baxter, J., Eisenbarth, G., Frank, N. & 208 others, Gesualdo, P., Hoffman, M., Ide, L., Karban, R., Liu, E., Norris, J., Waugh, K., Samper-Imaz, A., Steck, A., Schatz, D., Hopkins, D., Steed, L., Thomas, J., Silvis, K., Haller, M., Shankar, M., Sheehan, E., Gardiner, M., McIndoe, R., Liu, H., Nechtman, J., Sharma, A., Williams, J., Foghis, G., Anderson W., S. W., Beyerlein, A., Bonifacio, E., Hummel, M., Hummel, S., Foterek, K., Kersting, M., Knopff, A., Koletzko, S., Peplow, C., Roth, R., Schenke, J., Stock, J., Strauss, E., Warncke, K., Winkler, C., Simell G., O. G., Hyoty, H., Ilonen, J., Knip, M., Koivu, A., Koreasalo, M., Kahonen, M., Lonnrot, M., Multasuo, K., Mantymaki, E., Mykkanen, J., Nanto-Salonen, K., Niininen, T., Nyblom, M., Rautanen, J., Riikonen, A., Romo, M., Simell, A., Simell, B., Simell, T., Simell, V., Sjoberg, M., Stenius, A., Toppari, J., Varjonen, E., Veijola, R., Virtanen M., S. M., Akerlund, M., Agardh, D., Andrén-Aronsson, C., Ask, M., Bremer, J., Carlsson, U. M., Cilio, C., Ericson-Hallstrom, E., Fransson, L., Gard, T., Gerardsson, J., Hakansson, R., Hansen, M., Hansson, G., Hyberg, S., Johansen, F., Jonasdottir, B., Jonsson, L., Larsson, H., Lernmark, B., Mansson-Martinez, M., Markan, M., Massadakis, T., Melin, J., Mestan, Z., Nilsson, A., Nilsson, E., Rahmati, K., Rosenquist, A., Salami, F., Jarvirova, M. S., Sibthorpe, S., Sjoberg, B., Swartling, U., Trulsson, E., Torn, C., Wallin, A., Wimar, A., Aberg, S., Hagopian A., W. A., Yan, X., Killian, M., Crouch, C. C., Hay M., K. M., Ayres, S., Adams, C., Bratrude, B., Coughlin, D., Fowler, G., Franco, C., Hammar, C., Heaney, D., Marcus, P., Meyer, A., Mulenga, D., Scott, E., Skidmore, J., Stabbert, J., Stepitova, V., Williams, N., Becker, D., Franciscus, M., Dalmagro-Elias, M. E., Daftary, A., Klein, M. B., Abbondondolo, M., Austin-Gonzalez, S., Brown, R., Burkhardt, B., Butterworth, M., Cuthbertson, D., Eberhard, C., Fiske, S., Gowda, V., Lane, P., Liu, S., Liu, X., Malloy, J., McCarthy, C., McLeod, W., Smith, L., Tamura, R., Uusitalo, U., Vehik, K., Washington, E., Yang, J., Bourcier, K., Briese, T., Johnson, S. B., Oberste, S., Triplett, E., Yu, L., Miao, D., Bingley, P., Williams, A., Chandler, K., Rokni, S., Long, A., Boldison, J., Butterly, J., Broadhurst, J., Carreno, G., Curnock, R., Easton, P., Geoghan, I., Goode, J., Pearson, J., Reed, C., Ridewood, S., Wyatt, R., Eriksson, E. A., Karlsson, E. L., Erlund, I., Salminen, I., Sundvall, J., Leiviska, J., Lehtonen, M., Little R., R. R., Tennill L., A. L., Erlich, H., Bugawan, T., Alejandrino, M., Fiehn, O., Wikoff, B., Kind, T., Palazoglu, M., Wong, J., Wohlgemuth, G., Petrosino F., J. F., Marcovina M., S. M., Higgins, H., Ke, S., Zhao, Y., Jiang, N., Rich S., S. S., Chen, W. M., Onengut-Gumuscu, S., Farber, E., Pickin, R. R., Davis, J. & Gallo, D., Jul 2014, In : Diabetes/Metabolism Research and Reviews. 30, 5, p. 424-434 11 p.

Research output: Contribution to journalArticle

Type 1 Diabetes Mellitus
Biomarkers
Quality Control
Autoantibodies
Metagenomics
36 Citations (Scopus)

Children followed in the TEDDY study are diagnosed with type 1 diabetes at an early stage of disease

Elding Larsson, H., Vehik, K., Gesualdo, P., Akolkar, B., Hagopian, W., Krischer, J., Lernmark, Å., Rewers, M., Simell, O., She, J. X., Ziegler, A. & Haller, M. J., Mar 2014, In : Pediatric Diabetes. 15, 2, p. 118-126 9 p.

Research output: Contribution to journalArticle

Type 1 Diabetes Mellitus
Glutamate Decarboxylase
Class 8 Receptor-Like Protein Tyrosine Phosphatases
Glucose Tolerance Test
Autoantibodies
3 Citations (Scopus)

Pharmacophore-based discovery of new human dihydroorotate dehydrogenase inhibitor

Lu, P., Wang, Y., Ma, B., She, J., Zhang, Q., He, M. & Liu, Y., Jun 2014, In : Medicinal Chemistry. 10, 4, p. 402-408 7 p.

Research output: Contribution to journalArticle

Inhibitory Concentration 50
Chemical Databases
Random Allocation
Hydrogen
Costs and Cost Analysis
7 Citations (Scopus)

Prevalence of obesity was related to HLA-DQ in 2-4-year-old children at genetic risk for type 1 diabetes

Yang, J., Lernmark, Uusitalo, U. M., Lynch, K. F., Veijola, R., Winkler, C., Larsson, H. E., Rewers, M., She, J. X., Ziegler, A. G., Simell, O. G., Hagopian, W. A., Akolkar, B., Krischer, J. P. & Vehik, K., Dec 11 2014, In : International Journal of Obesity. 38, 12, p. 1491-1496 6 p.

Research output: Contribution to journalArticle

HLA Antigens
Type 1 Diabetes Mellitus
Obesity
Genotype
Body Size
19 Citations (Scopus)
Lymphocyte Activation
Type 1 Diabetes Mellitus
Autoantibodies
Genes
Gene Expression
14 Citations (Scopus)

Serum Dickkopf-1 (DKK1) is significantly lower in patients with lung cancer but is rapidly normalized after treatment

Xu, H., Wu, J., Chen, B., Li, M., Tian, Y., He, M., Xue, J., Wang, J., Bai, S., Sharma, A. K., Liu, H., Tang, J. & She, J-X., Jan 1 2014, In : American Journal of Translational Research. 6, 6, p. 850-856 7 p.

Research output: Contribution to journalArticle

Catenins
Lung Neoplasms
Serum
Cells
Non-Small Cell Lung Carcinoma
2 Citations (Scopus)
Thiadiazoles
Immunosuppressive Agents
formamide
benzofuran
4 Citations (Scopus)

Synthesis and in vitro evaluation of 1,3,4-thiadiazol-2-yl urea derivatives as novel AChE inhibitors

Xue, X. J., Wang, Y. B., Lu, P., Shang, H. F., She, J. X., Xia, L. X., Qian, H. & Huang, W. L., Jun 2014, In : Chemical and Pharmaceutical Bulletin. 62, 6, p. 524-527 4 p.

Research output: Contribution to journalArticle

Cholinesterase Inhibitors
Urea
Galantamine
Derivatives
Structure-Activity Relationship
12 Citations (Scopus)

Toxicity assessment of 7 anticancer compounds in zebrafish

Gao, X. P., Feng, F., Zhang, X. Q., Liu, X. X., Wang, Y. B., She, J-X., He, Z. H. & He, M. F., Jan 1 2014, In : International Journal of Toxicology. 33, 2, p. 98-105 8 p.

Research output: Contribution to journalArticle

Zebrafish
Mycophenolic Acid
Thalidomide
Toxicity
Paclitaxel
13 Citations (Scopus)

Transcriptomic changes induced by mycophenolic acid in gastric cancer cells

Dun, B., Sharma, A., Xu, H., Liu, H., Bai, S., Zeng, L. & She, J. X., 2014, In : American Journal of Translational Research. 6, 1, p. 28-42 15 p.

Research output: Contribution to journalArticle

Mycophenolic Acid
Stomach Neoplasms
Cells
Genes
Biological Phenomena
10 Citations (Scopus)
Squamous Cell Neoplasms
Serum Amyloid A Protein
Uterine Cervical Neoplasms
Blood Proteins
Carcinoembryonic Antigen
2013
12 Citations (Scopus)

Delineation of biological and molecular mechanisms underlying the diverse anticancer activities of mycophenolic acid

Dun, B., Xu, H., Sharma, A. K., Liu, H., Yu, H., Yi, B., Liu, X., He, M., Zeng, L. & She, J-X., Dec 5 2013, In : International Journal of Clinical and Experimental Pathology. 6, 12, p. 2880-2886 7 p.

Research output: Contribution to journalArticle

Mycophenolic Acid
Cell Line
Apoptosis
Cell Proliferation
Neoplasms
5 Citations (Scopus)

Enhanced T Cell Lymphoma in NOD.Stat5b Transgenic Mice Is Caused by Hyperactivation of Stat5b in CD8+ Thymocytes

Chen, B., Yi, B., Mao, R., Liu, H., Wang, J., Sharma, A., Peiper, S., Leonard, W. J. & She, J. X., Feb 14 2013, In : PloS one. 8, 2, e56600.

Research output: Contribution to journalArticle

Phosphorylation
thymocytes
T-cells
T-Cell Lymphoma
Thymocytes
29 Citations (Scopus)

Methods, quality control and specimen management in an international multicentre investigation of type 1 diabetes: TEDDY

Vehik, K., Fiske, S. W., Logan, C. A., Agardh, D., Cilio, C. M., Hagopian, W., Simell, O., Roivainen, M., She, J. X., Briese, T., Oikarinen, S., Hyoty, H., Ziegler, A. G., Rewers, M., Lernmark, A., Akolkar, B., Krischer, J. P. & Burkhardt, B. R., Oct 1 2013, In : Diabetes/Metabolism Research and Reviews. 29, 7, p. 557-567 11 p.

Research output: Contribution to journalArticle

Type 1 Diabetes Mellitus
Quality Control
Biomarkers
Autoantibodies
Autoimmunity
19 Citations (Scopus)

Mycophenolic acid inhibits migration and invasion of gastric cancer cells via multiple molecular pathways

Dun, B., Sharma, A., Teng, Y., Liu, H., Purohit, S., Xu, H., Zeng, L. & She, J. X., Nov 15 2013, In : PloS one. 8, 11, e81702.

Research output: Contribution to journalArticle

Mycophenolic Acid
stomach neoplasms
Stomach Neoplasms
Genes
Cells
22 Citations (Scopus)

Next-generation sequencing for viruses in children with rapid-onset type 1 diabetes

Lee, H. S., Briese, T., Winkler, C., Rewers, M., Bonifacio, E., Hyoty, H., Pflueger, M., Simell, O., She, J. X., Hagopian, W., Lernmark, A., Akolkar, B., Krischer, J. P. & Ziegler, A. G., Aug 1 2013, In : Diabetologia. 56, 8, p. 1705-1711 7 p.

Research output: Contribution to journalArticle

Type 1 Diabetes Mellitus
Viruses
Autoimmunity
Fever
Viremia
8 Citations (Scopus)

Serum protein profile at remission can accurately assess therapeutic outcomes and survival for serous ovarian cancer

Wang, J., Sharma, A., Ghamande, S. A., Bush, S., Ferris, D., Zhi, W., He, M., Wang, M., Wang, X., Miller, E., Hopkins, D., Macfee, M., Guan, R., Tang, J. & She, J. X., Nov 11 2013, In : PloS one. 8, 11, e78393.

Research output: Contribution to journalArticle

ovarian neoplasms
remission
Ovarian Neoplasms
blood proteins
Blood Proteins
13 Citations (Scopus)

Systematic evaluation of 640 FDA drugs for their effect on CD4 +Foxp3+ regulatory T cells using a novel cell-based high throughput screening assay

Mao, R., Xiao, W., Liu, H., Chen, B., Yi, B., Kraj, P. & She, J-X., May 15 2013, In : Biochemical Pharmacology. 85, 10, p. 1513-1524 12 p.

Research output: Contribution to journalArticle

High-Throughput Screening Assays
T-cells
Regulatory T-Lymphocytes
Assays
Screening
17 Citations (Scopus)

The expression of inflammatory genes is upregulated in peripheral blood of patients with type 1 diabetes

Jin, Y., Sharma, A. K., Davis, C. M., Hopkins, D., Wang, X., Robertson, D. G., Bode, B., Anderson, S. W., Reed, J. C., Steed, R. D., Steed, L. & She, J-X., Sep 1 2013, In : Diabetes Care. 36, 9, p. 2794-2802 9 p.

Research output: Contribution to journalArticle

Type 1 Diabetes Mellitus
Gene Expression
Genes
Antigen Presentation
Myeloid Cells
2012
29 Citations (Scopus)

Confirmation of novel type 1 diabetes risk loci in families

Cooper, J. D., Howson, J. M. M., Smyth, D., Walker, N. M., Stevens, H., Yang, J. H. M., She, J. X., Eisenbarth, G. S., Rewers, M., Todd, J. A., Akolkar, B., Concannon, P., Erlich, H. A., Julier, C., Morahan, G., Nerup, J., Nierras, C., Pociot, F. & Rich, S. S., Apr 1 2012, In : Diabetologia. 55, 4, p. 996-1000 5 p.

Research output: Contribution to journalArticle

Type 1 Diabetes Mellitus
Genome-Wide Association Study
Genotype
Genetic Association Studies
Population