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Research Output 1987 2020

2012
4 Citations (Scopus)

Detection of lactobacilli in monthly mail-in stool samples from 3-18 months old infants at genetic risk for type 1 diabetes

Salami, F., Abels, M., Hyöty, H., Vaziri-Sani, F., Aronsson, C. A., Vehik, K., Delli, A., Hagopian, W. A., Rewers, M., Ziegler, A. G., Simell, O., Akolkar, B., Krischer, J., She, J. & Leramark, Å., Dec 1 2012, In : International Journal of Probiotics and Prebiotics. 7, 3-4, p. 135-144 10 p.

Research output: Contribution to journalArticle

insulin-dependent diabetes mellitus
Postal Service
Lactobacillus
Type 1 Diabetes Mellitus
Sweden
24 Citations (Scopus)

Differences in recruitment and early retention among ethnic minority participants in a large pediatric cohort: The TEDDY Study

Baxter, J., Vehik, K., Johnson, S. B., Lernmark, B., Roth, R., Simell, T., Rewers, M., Barriga, K., Bautista, K., Baxter, J., Eisenbarth, G., Frank, N., Gesualdo, P., Hoffman, M., Ide, L., Karban, R., Liu, E., Norris, J., Waugh, K., Samper-Imaz, A. & 149 others, Steck, A., She, J-X., Schatz, D., Hopkins, D., Steed, L., Thomas, J., Silvis, K., Haller, M., Shankar, M., English, K., McIndoe, R. A., Liu, H., Nechtman, J., Williams, J., Foghis, G., Stephen, W., Anderson, M. D., Ziegler, A. G., Achenbach, A., Boerschmann, H., Bonifacio, E., Bunk, M., Försch, J., Henneberger, L., Hummel, M., Hummel, S., Joslowski, G., Kersting, M., Knopff, A., Kocher, N., Koletzko, S., Krause, S., Mann, A., Matzke, C., Mittermeier, A., Peplow, C., Pflüger, M., Ramminger, C., Strauss, E., Rash-Sur, S., Roth, R., Schenkel, J., Stock, J., Voit, K., Winkler, C., Wosch, A., Zwilling, M., Simell, O. G., Nanto-Salonen, K., Ilonen, J., Knip, M., Tuula Simell, V., Hyöty, H., Virtanen, S. M., Kronberg-Kippilä, C., Sjöberg, M., Simell, B., Ruohonen, E., Romo, M., Mantymaki, E., Schroderus, H., Nyblom, M., Stenius, A., Lernmark, Å., Agardh, D., Almgren, P., Andersson, E., Andrén-Aronsson, C., Ask, M., Karlsson, U. M., Cilio, C., Bremer, J., Ericson-Hallström, E., Gard, T., Gerardsson, J., Hansson, G., Hansen, M., Hyberg, S., Håkansson, R., Johansen, F., Jonsson, L., Larsson, H., Lernmark, B., Markan, M., Massadakis, T., Melin, J., Månsson-Martinez, M., Nilsson, A., Rahmati, K., Järvirova, M. S., Sibthorpe, S., Sjöberg, B., Skogberg, A., Törn, C., Wallin, A., Wimar, Å., Åberg, S., Hagopian, W. A., Yan, X., Killian, M., Cowen Crouch, C., Hay, K. M., Ayres, S., Adams, C., Bratrude, B., Coughlin, D., Fowler, G., Franco, C., Hammar, C., Heaney, D., Marcus, P., Meyer, A., Mulenga, D., Scott, E., Skidmore, J., Stabbert, J., Stepitova, V., Williams, N., Becker, D., Franciscus, M., Dalmagro-Elias, M. E., Daftary, A., Krischer, J. P., Abbondondolo, M., Ballard, L., Brown, R., Burkhardt, B., Cuthbertson, D., Eberhard, C., Fiske, S., Gowda, V., Hadley, D., Lee, H. S., Liu, S., Lynch, K., Malloy, J., McCarthy, C., McLeod, W., Smith, L., Smith, S., Uusitalo, U., Vehik, K., Washington, E., Yang, J., Akolkar, B., Briese, T., Erlich, H., Johnson, S. B. & Oberste, S., Jul 1 2012, In : Contemporary Clinical Trials. 33, 4, p. 633-640 8 p.

Research output: Contribution to journalArticle

Type 1 Diabetes Mellitus
Pediatrics
Minority Groups
Hispanic Americans
Ethnic Groups
39 Citations (Scopus)

Evidence of gene-gene interaction and age-at-diagnosis effects in type 1 diabetes

Howson, J. M. M., Cooper, J. D., Smyth, D. J., Walker, N. M., Stevens, H., She, J. X., Eisenbarth, G. S., Rewers, M., Todd, J. A., Akolkar, B., Concannon, P., Erlich, H. A., Julier, C., Morahan, G., Nerup, J., Nierras, C., Pociot, F. & Rich, S. S., Nov 1 2012, In : Diabetes. 61, 11, p. 3012-3017 6 p.

Research output: Contribution to journalArticle

Type 1 Diabetes Mellitus
Genotype
Genes
Interleukin-2
CTLA-4 Antigen
5 Citations (Scopus)

Novel biomarkers in type 1 diabetes

Jin, Y. & She, J. X., Dec 1 2012, In : Review of Diabetic Studies. 9, 4, p. 224-235 12 p.

Research output: Contribution to journalReview article

Type 1 Diabetes Mellitus
Biomarkers
Autoantibodies
Proteomics
Genes
5 Citations (Scopus)
Inbred NOD Mouse
T-cells
Regulatory T-Lymphocytes
Medical problems
Up-Regulation
9 Citations (Scopus)
Insulin-Like Growth Factor Binding Protein 6
Diabetes Complications
Medical problems
Type 1 Diabetes Mellitus
Serum
2011
58 Citations (Scopus)

Association between type 1 diabetes and GWAS SNPs in the southeast US Caucasian population

Reddy, M. P. L., Wang, H., Liu, S., Bode, B., Reed, J. C., Steed, R. D., Anderson, S. W., Steed, L., Hopkins, D. & She, J-X., Apr 1 2011, In : Genes and Immunity. 12, 3, p. 208-212 5 p.

Research output: Contribution to journalArticle

Southeastern United States
Genome-Wide Association Study
Type 1 Diabetes Mellitus
Single Nucleotide Polymorphism
Interleukin-27
101 Citations (Scopus)

Central (ICV) leptin injection increases bone formation, bone mineral density, muscle mass, serum IGF-1, and the expression of osteogenic genes in leptin-deficient ob/ob mice

Bartell, S. M., Rayalam, S., Ambati, S., Gaddam, D. R., Hartzell, D. L., Hamrick, M. W., She, J-X., Della-Fera, M. A. & Baile, C. A., Aug 1 2011, In : Journal of Bone and Mineral Research. 26, 8, p. 1710-1720 11 p.

Research output: Contribution to journalArticle

Leptin
Insulin-Like Growth Factor I
Osteogenesis
Bone Density
Gene Expression
16 Citations (Scopus)

Chemokine (c-c motif) ligand 2 (ccl2) in sera of patients with type 1 diabetes and diabetic complications

Guan, R., Purohit, S. B., Wang, H., Bode, B., Reed, J. C., Steed, R. D., Anderson, S. W., Steed, L., Hopkins, D., Xia, C. & She, J-X., Apr 21 2011, In : PloS one. 6, 4, e17822.

Research output: Contribution to journalArticle

insulin-dependent diabetes mellitus
Chemokine CCL2
Diabetes Complications
Medical problems
Type 1 Diabetes Mellitus
5 Citations (Scopus)

Country-specific birth weight and length in type 1 diabetes high-risk HLA genotypes in combination with prenatal characteristics

Sterner, Y., Törn, C., Lee, H. S., Larsson, H., Winkler, C., McLeod, W., Lynch, K., Simell, O., Ziegler, A., Schatz, D., Hagopian, W., Rewers, M., She, J. X., Krischer, J. P., Akolkar, B. & Lernmark, Å., Dec 1 2011, In : Journal of Perinatology. 31, 12, p. 764-769 6 p.

Research output: Contribution to journalArticle

HLA Antigens
Type 1 Diabetes Mellitus
Birth Weight
Genotype
Parturition
11 Citations (Scopus)

Delineating the angiogenic gene expression profile before pulmonary vascular remodeling in a lamb model of congenital heart disease

Tian, J., Fratz, S., Hou, Y., Lu, Q., Görlach, A., Hess, J., Schreiber, C., Datar, S. A., Oishi, P., Nechtman, J., Podolsky, R., She, J. X., Fineman, J. R. & Black, S. M., Jan 1 2011, In : Physiological Genomics. 43, 2, p. 87-98 12 p.

Research output: Contribution to journalArticle

Transcriptome
Heart Diseases
Lung
Fibroblast Growth Factor 2
Genes

Developments in small molecule immunosuppressive drugs

Liu, Y., Wang, Y. B., Zhang, Q. & She, J-X., Oct 30 2011, In : Chinese Journal of New Drugs. 20, 20, p. 1981-1988 8 p.

Research output: Contribution to journalReview article

Immunosuppressive Agents
Pharmaceutical Preparations
Janus Kinase 3
Tacrolimus
Organ Transplantation
38 Citations (Scopus)

Discovery and validation of serum protein changes in type 1 diabetes patients using high throughput two dimensional liquid chromatography-mass spectrometry and immunoassays.

Zhi, W., Sharma, A., Purohit, S., Miller, E., Bode, B., Anderson, S. W., Reed, J. C., Steed, R. D., Steed, L., Hopkins, D. & She, J. X., Nov 1 2011, In : Molecular & cellular proteomics : MCP. 10, 11

Research output: Contribution to journalArticle

Liquid chromatography
Medical problems
Type 1 Diabetes Mellitus
Immunoassay
Liquid Chromatography
8 Citations (Scopus)
Inbred NOD Mouse
Focal Adhesions
Gene Expression Profiling
Lacrimal Apparatus
Leukocytes
4 Citations (Scopus)

Lack of an association of miR-938 SNP in IDDM10 with human type 1 diabetes

Mi, X., He, H., Deng, Y., Levin, A. M., She, J-X., Mi, Q. S. & Zhou, L., Oct 21 2011, In : Diabetology and Metabolic Syndrome. 3, 1, 27.

Research output: Contribution to journalArticle

Type 1 Diabetes Mellitus
Single Nucleotide Polymorphism
MicroRNAs
Interleukin-16
Small Untranslated RNA
75 Citations (Scopus)

Reduced serum vitamin D-binding protein levels are associated with type 1 diabetes

Blanton, D., Han, Z., Bierschenk, L., Linga-Reddy, M. V. P., Wang, H., Clare-Salzler, M., Haller, M., Schatz, D., Myhr, C., She, J-X., Wasserfall, C. & Atkinson, M., Oct 1 2011, In : Diabetes. 60, 10, p. 2566-2570 5 p.

Research output: Contribution to journalArticle

Vitamin D-Binding Protein
Type 1 Diabetes Mellitus
Blood Proteins
Vitamin D
Single Nucleotide Polymorphism
18 Citations (Scopus)
Isotopes
Labeling
Mass spectrometry
Monitoring
Assays

Synthesis of saracatinib

Shang, H. F., Wang, Y. B., Zhao, D. M., Zhang, Q. & She, J-X., Dec 15 2011, In : Chinese Journal of New Drugs. 20, 23, p. 2363-2366 4 p.

Research output: Contribution to journalArticle

src-Family Kinases
Cyclization
Hydrolysis
saracatinib
Proton Magnetic Resonance Spectroscopy
116 Citations (Scopus)

The Environmental Determinants of Diabetes in the Young (TEDDY): Genetic criteria and international diabetes risk screening of 421 000 infants

Hagopian, W. A., Erlich, H., Lernmark, Å., Rewers, M., Ziegler, A. G., Simell, O., Akolkar, B., Vogt, R., Blair, A., Ilonen, J., Krischer, J. & She, J., Dec 1 2011, In : Pediatric Diabetes. 12, 8, p. 733-743 11 p.

Research output: Contribution to journalArticle

HLA Antigens
Type 1 Diabetes Mellitus
Costs and Cost Analysis
Population
Genotyping Techniques
2010
4 Citations (Scopus)
Biomarkers
Medical problems
Type 1 Diabetes Mellitus
Technology
Throughput
19 Citations (Scopus)

Autoimmunity predominates in a large South African cohort with addison's disease of mainly European descent despite long-standing disease and is associated with HLA DQB*0201

Ross, I., Boulle, A., Soule, S., Levitt, N., Pirie, F., Karlsson, A., Mienie, J., Yang, P., Wang, H., She, J-X., Winter, W. & Schatz, D., Sep 1 2010, In : Clinical Endocrinology. 73, 3, p. 291-298 8 p.

Research output: Contribution to journalArticle

Addison Disease
HLA Antigens
Autoimmunity
Autoantibodies
Steroid 21-Hydroxylase
13 Citations (Scopus)
Type 1 Diabetes Mellitus
National Institute of Diabetes and Digestive and Kidney Diseases (U.S.)
Siblings
HLA Antigens
North America
1 Citation (Scopus)

Erratum: Loss-of-function mutations in HPSE2 cause the autosomal recessive urofacial syndrome (The American Journal of Human Genetics (2010) 86 (957-962))

Pang, J., Zhang, S., Yang, P., Lee, B. H., Zhong, J., Zhang, Y., Ochoa, B., Agundez, J. A. G., Voelckel, M. A., Fisher, R. B., Gu, W., Xiong, W., Mei, L., She, J-X. & Wang, C. Y., Jul 9 2010, In : American Journal of Human Genetics. 87, 1, 1 p.

Research output: Contribution to journalComment/debate

Medical Genetics
Mutation
Urofacial syndrome
25 Citations (Scopus)

Genetically dependent ERBB3 expression modulates antigen presenting cell function and type 1 diabetes risk

Wang, H., Jin, Y., Reddy, M. V. P. L., Podolsky, R., Liu, S., Yang, P., Bode, B., Reed, J. C., Steed, R. D., Anderson, S. W., Steed, L., Hopkins, D., Huang, Y. & She, J-X., Aug 20 2010, In : PloS one. 5, 7, e11789.

Research output: Contribution to journalArticle

antigen-presenting cells
insulin-dependent diabetes mellitus
Antigen-Presenting Cells
Medical problems
Type 1 Diabetes Mellitus
19 Citations (Scopus)

Hepatic gene expression profiling reveals key pathways involved in leptin-mediated weight loss in ob/ob mice

Sharma, A., Bartell, S. M., Baile, C. A., Chen, B., Podolsky, R. H., McIndoe, R. A. & She, J. X., Oct 20 2010, In : PloS one. 5, 8, e12147.

Research output: Contribution to journalArticle

Gene Expression Profiling
Leptin
leptin
Gene expression
Weight Loss
41 Citations (Scopus)

Loss-of-Function Mutations in HPSE2 Cause the Autosomal Recessive Urofacial Syndrome

Pang, J., Zhang, S., Yang, P., Lee, B. H., Zhong, J., Zhang, Y., Ochoa, B., Agundez, J. A. G., Voelckel, M. A., Gu, W., Xiong, W., Mei, L., She, J-X. & Wang, C. Y., Jul 11 2010, In : American journal of human genetics. 86, 6, p. 957-962 6 p.

Research output: Contribution to journalArticle

Mutation
Genes
Facial Expression
Colombia
Hydrolases
87 Citations (Scopus)

MicroRNA-34a is induced via p53 during cisplatin nephrotoxicity and contributes to cell survival

Bhatt, K., Zhou, L., Mi, Q. S., Huang, S., She, J-X. & Dong, Z., Sep 1 2010, In : Molecular Medicine. 16, 9-10, p. 409-416 8 p.

Research output: Contribution to journalArticle

MicroRNAs
Cisplatin
Cell Survival
Acute Kidney Injury
Kidney
40 Citations (Scopus)

Porous-wall hollow glass microspheres as novel potential nanocarriers for biomedical applications

Li, S., Nguyen, L., Xiong, H., Wang, M., Hu, T. C. C., She, J-X., Serkiz, S. M., Wicks, G. G. & Dynan, W. S., Jan 1 2010, In : Nanomedicine: Nanotechnology, Biology, and Medicine. 6, 1, p. 127-136 10 p.

Research output: Contribution to journalArticle

Microspheres
Glass
Antibodies
Single-Chain Antibodies
Immunoglobulin Fragments
6 Citations (Scopus)

Proficiency testing of human leukocyte antigen-DR and human leukocyte antigen-DQ genetic risk assessment for type 1 diabetes using dried blood spots

Dantonio, P., Meredith-Molloy, N., Hagopian, W. A., She, J. X., Akolkar, B., Cordovado, S. K., Hendrix, M., Henderson, L. O., Hannon, W. H. & Vogt, R. F., Jul 2010, In : Journal of Diabetes Science and Technology. 4, 4, p. 929-941 13 p.

Research output: Contribution to journalArticle

Antigens
Medical problems
HLA Antigens
Type 1 Diabetes Mellitus
Risk assessment
33 Citations (Scopus)

Proteomic technologies for the discovery of type 1 diabetes biomarkers

Zhi, W., Purohit, S., Carey, C., Wang, M. & She, J. X., Jul 2010, In : Journal of Diabetes Science and Technology. 4, 4, p. 993-1002 10 p.

Research output: Contribution to journalReview article

Biomarkers
Medical problems
Type 1 Diabetes Mellitus
Proteomics
Technology
2009
7 Citations (Scopus)

Analyses of multiple single-nucleotide polymorphisms in the SUMO4/IDDM5 region in affected sib-pair families with type i diabetes

Podolsky, R., Prasad Linga-Reddy, M. V. & She, J. X., Dec 1 2009, In : Genes and Immunity. 10, SUPPL. 1, p. S16-S20

Research output: Contribution to journalArticle

Type 1 Diabetes Mellitus
Single Nucleotide Polymorphism
Population
Genes
Autoimmune Diseases
21 Citations (Scopus)

APC dysfunction is correlated with defective suppression of T cell proliferation in human type 1 diabetes

Jin, Y., Chen, X., Podolsky, R., Hopkins, D., Makala, L. H., Muir, A. & She, J-X., Mar 1 2009, In : Clinical Immunology. 130, 3, p. 272-279 8 p.

Research output: Contribution to journalArticle

Antigen-Presenting Cells
Type 1 Diabetes Mellitus
Cell Proliferation
T-Lymphocytes
Viral Tumor Antigens
8 Citations (Scopus)

A statistical framework for integrating two microarray data sets in differential expression analysis

Lai, Y., Eckenrode, S. E. & She, J. X., Jan 30 2009, In : BMC Bioinformatics. 10, SUPPL. 1, S23.

Research output: Contribution to journalArticle

Differential Expression
Microarrays
Microarray Data
Data integration
Genes
27 Citations (Scopus)
Xerostomia
Inbred NOD Mouse
Salivary Glands
Gene Expression
Genes
25 Citations (Scopus)
Keratoconjunctivitis Sicca
Lacrimal Apparatus
Inbred NOD Mouse
Gene Expression
Genes
35 Citations (Scopus)

Effect of PPARγ inhibition on pulmonary endothelial cell gene expression: Gene profiling in pulmonary hypertension

Tian, J., Smith, A., Nechtman, J., Podolsky, R., Aggarwal, S., Snead, C., Kumar, S., Elgaish, M., Oishi, P., Göerlach, A., Fratz, S., Hess, J., Catravas, J. D., Verin, A. D., Fineman, J. R., She, J. X. & Black, S. M., Jan 1 2009, In : Physiological Genomics. 40, 1, p. 48-60 13 p.

Research output: Contribution to journalArticle

PPAR gamma
Gene Expression Profiling
Pulmonary Hypertension
Endothelial Cells
Lung
1067 Citations (Scopus)

Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes

Barrett, J. C., Clayton, D. G., Concannon, P., Akolkar, B., Cooper, J. D., Erlich, H. A., Julier, C., Morahan, G., Nerup, J., Nierras, C., Plagnol, V., Pociot, F., Schuilenburg, H., Smyth, D. J., Stevens, H., Todd, J. A., Walker, N. M., Rich, S. S., Baskerville, T., Bautista, N. & 380 others, Bhatia, E., Bhatia, V., Bin Hasan, K., Bonnici, F., Brodnicki, T., Cameron, F., Chaichanwatanakul, K., Cheung, P. T., Colman, P., Cotterill, A., Couper, J., Cutfield, R., Davis, T., Dixon, P., Donaghue, K., Dowling, K., Drury, P., Dye, S., Gellert, S., Abdul Ghani, R., Greer, R., Han, X., Harrison, L., Homatopoulos, N., Ji, L., Jones, T., Yin, L. K., Kamaruddin, N. A., Kanga, U., Kanungo, A., Kaur, G., Kek, B., Knowles, S., Krebs, J., Kumar, N., Lee, Y. J., Li, X., Liktimaskul, S., Lloyd, M., Loth, A., Louey, A., Mehra, N., Merriman, T., Min, L., Morahan, G., Moses, R., Mraz, G., Murphy, R., Nicholson, I., Panelo, A., Poh, P., Price, G., Ratnam, N., Sanjeevi, C., Sedimbi, S., Shen, S., Ying, G. S., Tait, B., Tandon, N., Thomas, A., Varney, M., Weerakulwattana, P., Willis, J., Albret, L., Ampudia-Blasco, F., Argente, J., Babadjanova, G., Badenhoop, K., Battelino, T., Beilhack, G., Bergholdt, R., Bingley, P., Boehm, B., Bolidson, J., Brorsson, C., Carlson, J., Castano, L., Chandler, K., Cinek, O., Cipponeri, E., Corripio, R., Garcia Cuartero, B., de Leiva, A., Fagulha, A., Fernandez Balcells, M., Guja, C., Gutierrez, P., Hatziagelaki, E., Heath, S., Helmberg, W., Hernandez, M., Holzheu, I., Hosszufalusi, N., Ionescu-Tirgoviste, C., Johannesen, J., Julier, C., Kahles, H., Knip, M., Kockum, I., Kojo, E., Koprivarova, K., Kordonouri, O., Kretowski, A., Krikovszky, D., Kurkhaus, A., Lalic, N., Lavant, E., Long, A., Ludvigsson, J., Madacsy, L., Marga, M., Mauricio, D., Mazurkievicz, G., Nerup, J., Novoa Mogollon, F. J., Petersen, M. T., Phillip, M., Pirags, V., Pociot, F., Pozzilli, P., Rappner, R., Roep, B., Rokni, S., Rosinger, S., Rubio-Cabezas, O., Ruckgaber, C., Satman, I., Schober, E., Seufert, J., Sing, R., Skrha, J., Sobngwi, E., Somerville, M., Spinas, G., Tilmann, V., Undlien, D., Urbanavicius, V., Van der Auwera, B., Vasquez San Miguel, F., Vazeo-Gerasimidi, A., Velickiene, D., Wagner, A., Williams, A., Wurzburger, M., Ziegler, A., Agleham, M., Aldrich, A., Alemzadeh, R., Aly, T., Arora, S., Austin, A., Becker, D., Benoist, C., Berka, N., Bhatia, S., Bonella, P., Bottini, N., Boyle, S., Brady, B., Brickman, W., Christensen, R., Concannon, P., Couch, R., Counts, D., Crandall, J., Daniels, M., Dolan, L., Donaldson, D., Doria, A., Eisenbarth, G., El-Hajj, R., Erlich, H., Fain, P., Fear, A. L., Ferry, R., Fiallo-Scharer, R., Ghosh, S., Gitelman, S., Godwin, M., Goland, R., Goodman, N., Goodwin, G., Gravely, J., Greenbaum, C., Gudgeon, C., Gunville, F., Hagopian, W., Hakonarson, H., Hansen, J., Harrington, K., Hassing, J., Hilliker, W., Hoffman, R., Hulbert, E., Izquierdo, R., Jospe, N., Kaiserman, K., Kaufman, F., Kim, S., Kloos, E., Kosoy, R., Lane, J., Lane, J., Lawrence, J., Levetan, C., Levin, P., Lipton, R., Lonsdale, J., Magnuson, V., Marks, J., Mayer-Davis, B., McEvoy, R., McIndoe, R. A., Merkle, L., Metzger, D., Miao, D., Mickelson, E., Moonsamy, P., Moore, W., Moran, A., Noble, J., Olsem, G., Onengut-Gumuscu, S., Orban, T., Orlowski, C., Paterson, A., Pietropaolo, M., Pihoker, C., Polychronakos, C., Post, J., Postellon, D., Pugliese, A., Qu, H., Quattrin, T., Rappaport, M., Raskin, P., Risbeck, H., Rodriguez, H., Rodriguez, L., Rogers, M., Russell, B., Schatz, D., Scott, C., She, J-X., Shulman, D., Soyka, L., Speiser, P., Starkman, H., Steck, A., Stender, S., Stratton, L., Sur, D., Taback, S., Thrailkill, K., Toth, E., Trymbiski, P., Tsalikian, E., Vertachnik, K., Wahlen, J., Wang, X., Weber, S., Wherrett, D., Willi, S., Wilson, D., Youkey, J., Young, N., Yu, L., Zimmerman, D., Adlem, E., Allen, J., Brown, J., Burren, O., Clarke, P., Clayton, D., Coleman, G., Cooper, J., Cucca, F., Duley, S., Dunger, D., Everett, V., Hardy, M., Harrison, D., Harrison, I., Hawkins, S., Healy, B., Hood, S., Howell, S., Maisuria, M., Meadows, W., Mistry, T., Nutland, S., Ovington, N., Schuilenburg, H., Simpson, A., Smink, L., Stevens, H., Taylor, N., Todd, J., Tuomilehto, J., Walker, N., Widmer, B., Wilson, M., Withers, H., Brown, M., Chen, W. M., Crews, A., Griffin, J., Hall, M., Harnish, T., Hepler, J., Hilner, J., King, N., Lohman, K., Lu, L., Mychaleckyj, J., Nail, J., Perdue, L., Pierce, J., Reboussin, D., Rich, S., Rushing, S., Sale, M., Sides, E., Snively, B., Teuschler, H., Theil, G., Williams, D., Akolkar, B., McKeon, C., Nierras, C., Thomson, E., Altshuler, D., Au, K., Bain, S., Barcellos, L., Barral, S., Becker, T., Briggs, F., Bronson, P., Daly, M., de Bakker, P., Deloukas, P., Devlin, B., Eike, M. C., Field, L., Gabriel, S., Garge, N., Gaudieri, S., Goldstein, B., Gorodezky, C., Hamon, S., He, C., Howson, J., Humphreys, K., James, I., Lathrop, M., Lie, B. A., Li, D., Mack, S., McGinnis, R., McKinnon, E., McLaren, W., Nolan, D., Olsson, M., Ott, J., Owerbach, D., Patterson, C., Podolsky, R., Ramsay, P., Rangantah, V., Risch, N., Ronningen, K. S., Shao, X., Single, R., Steffes, M., Thomson, G., Valdes, A. M., Vandiedonck, C., Whittaker, P. & Zhang, Q., Jun 1 2009, In : Nature Genetics. 41, 6, p. 703-707 5 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Type 1 Diabetes Mellitus
Meta-Analysis
Interleukin-27
Interleukin-10
6 Citations (Scopus)

Greater fractalkine expression in mesenteric arteries of female spontaneously hypertensive rats compared with males

Sullivan, J. C., Pardieck, J. L., Doran, D., Zhang, Y., She, J. X. & Pollock, J. S., Apr 1 2009, In : American Journal of Physiology - Heart and Circulatory Physiology. 296, 4, p. H1080-H1088

Research output: Contribution to journalArticle

Chemokine CX3CL1
Mesenteric Arteries
Inbred SHR Rats
Arteries
Tumor Necrosis Factor-alpha
105 Citations (Scopus)

IFIH1 polymorphisms are significantly associated with type 1 diabetes and IFIH1 gene expression in peripheral blood mononuclear cells

Liu, S., Wang, H., Jin, Y., Podolsky, R., Reddy, M. V. P. L., Pedersen, J., Bode, B., Reed, J., Steed, D., Anderson, S., Yang, P., Muir, A., Steed, L., Hopkins, D., Huang, Y., Purohit, S. B., Wang, C. Y., Steck, A. K., Montemari, A., Eisenbarth, G. & 2 others, Rewers, M. & She, J-X., Jan 1 2009, In : Human Molecular Genetics. 18, 2, p. 358-365 8 p.

Research output: Contribution to journalArticle

Type 1 Diabetes Mellitus
Single Nucleotide Polymorphism
Blood Cells
Gene Expression
Chromosomes, Human, Pair 5
19 Citations (Scopus)

rs2476601 T allele (R620W) defines high-risk PTPN22 type I diabetes-associated haplotypes with preliminary evidence for an additional protective haplotype

Type I Diabetes Genetics Consortium, Dec 2009, In : Genes and Immunity. 10, p. S21-S26

Research output: Contribution to journalArticle

Non-Receptor Type 22 Protein Tyrosine Phosphatase
Type 1 Diabetes Mellitus
Haplotypes
Alleles
Single Nucleotide Polymorphism
75 Citations (Scopus)

Tie2cre-induced inactivation of the miRNA-processing enzyme Dicer disrupts invariant NKT cell development

Zhou, L., Seo, K. H., He, H. Z., Pacholczyk, R. W., Meng, D. M., Li, C. G., Xu, J., She, J-X., Dong, Z. & Mi, Q. S., Jun 23 2009, In : Proceedings of the National Academy of Sciences of the United States of America. 106, 25, p. 10266-10271 6 p.

Research output: Contribution to journalArticle

Ribonuclease III
Natural Killer T-Cells
MicroRNAs
Thymus Gland
Homeostasis
2008
44 Citations (Scopus)

A stress-dependent SUMO4 sumoylation of its substrate proteins

Wei, W., Yang, P., Pang, J., Zhang, S., Wang, Y., Wang, M-H., Dong, Z., She, J-X. & Wang, C. Y., Oct 24 2008, In : Biochemical and Biophysical Research Communications. 375, 3, p. 454-459 6 p.

Research output: Contribution to journalArticle

Sumoylation
Small Ubiquitin-Related Modifier Proteins
Hydrolases
Substrates
Luciferases
82 Citations (Scopus)

Extracellular high-mobility group box 1 acts as an innate immune mediator to enhance autoimmune progression and diabetes onset in NOD mice

Han, J., Zhong, J., Wei, W., Wang, Y., Huang, Y., Yang, P., Purohit, S. B., Dong, Z., Wang, M-H., She, J-X., Gong, F., Stern, D. M. & Wang, C. Y., Aug 1 2008, In : Diabetes. 57, 8, p. 2118-2127 10 p.

Research output: Contribution to journalArticle

Inbred NOD Mouse
Type 1 Diabetes Mellitus
Dendritic Cells
Autoimmunity
T-Lymphocytes
43 Citations (Scopus)

SUMO4 and its role in type 1 diabetes pathogenesis

Wang, C. Y. & She, J. X., Feb 1 2008, In : Diabetes/Metabolism Research and Reviews. 24, 2, p. 93-102 10 p.

Research output: Contribution to journalReview article

Medical problems
Type 1 Diabetes Mellitus
Genes
Modifier Genes
Cloning
146 Citations (Scopus)

The environmental determinants of diabetes in the young (TEDDY) study

Rewers, M., She, J. X., Ziegler, A. G., Simell, O. G., Lernmark, Å., Hagopian, W. A., Krischer, J. P. & Akolkar, B., Dec 2008, Immunology of Diabetes V From Bench to Bedside. Blackwell Publishing Inc., p. 1-13 13 p. (Annals of the New York Academy of Sciences; vol. 1150).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Medical problems
Type 1 Diabetes Mellitus
Newborn Infant
Autoimmunity
HLA-DQ Antigens
11 Citations (Scopus)

The IL-10 and IFN-γ pathways are essential to the potent immunosuppressive activity of cultured CD8+ NKT-like cells

Zhou, L., Wang, H., Zhong, X., Jin, Y., Mi, Q. S., Sharma, A. K., McIndoe, R. A., Garge, N., Podolsky, R. & She, J-X., Jul 29 2008, In : Genome Biology. 9, 7, R119.

Research output: Contribution to journalArticle

immunosuppressive agents
Natural Killer T-Cells
Immunosuppressive Agents
interleukin-10
Interleukin-10
33 Citations (Scopus)

Type 1 diabetes patients have significantly lower frequency of plasmacytoid dendritic cells in the peripheral blood

Chen, X., Makala, L. H. C., Jin, Y., Hopkins, D., Muir, A., Garge, N., Podolsky, R. H. & She, J. X., Dec 1 2008, In : Clinical Immunology. 129, 3, p. 413-418 6 p.

Research output: Contribution to journalArticle

Type 1 Diabetes Mellitus
Dendritic Cells
Population Control
Autoimmune Diseases
Immunity
2007
44 Citations (Scopus)

A high-throughput population screening system for the estimation of genetic risk for type 1 diabetes: An application for the TEDDY (The Environmental Determinants of Diabetes in the Young) study

Kiviniemi, M., Hermann, R., Nurmi, J., Ziegler, A. G., Knip, M., Simell, O., Veijola, R., Lövgren, T., Ilonen, J., Rewers, M., Barriga, K., Baxter, J., Deas, A., Eisenbarth, G., Emery, L., Gesualdo, P., Hoffman, M., Norris, J., Waugh, K., Weber, S. & 88 others, She, J-X., Muir, A., Schatz, D., Hopkins, D., Steed, L., Choate, A., Silvis, K., Shankar, M., Huang, Y. H., Yang, P., Zheng, W. P., Wang, H. J., English, K., McIndoe, R. A., Bonifacio, E., Baumgarten, A., Hummel, S., Kersting, M., Koenig, S., Knopff, A., Locher, A., Roth, R., Schoen, S., Schwaiger, P., Sichert-Hellert, W., Winkler, C., Zimmermann, D., Nanto-Salonen, K., Simell, T., Uusitalo, U., Hyöty, H., Virtanen, S. M., Kronberg-Kippilä, C., Torma, M., Ruohonen, E., Romo, M., Mantymaki, E., Niininen, T., Nyblom, M., Stenius, A., Lernmark, Å., Almgren, P., Andrén-Aronsson, C., Andersson, E., Bianconi-Svensson, S., Carlsson, U. M., Cilio, C., Gerardsson, J., Gustavsson, B., Hansson, A., Hansson, G., Hansson, I., Ivarsson, S., Larsson, H., Karlsson, E., Katsarou, A., Lernmark, B., Massadakis, T., Nilsson, A., Järvirova, M. S., Sjöberg, B., Wallin, A., Wimar, Å., Hagopian, W. A., Brantley, M., Cowen, C., Hui, P., Hay, K. M., Jackson, M., Stepikova, V., Ugale, J., Krischer, J. P., Bray, C., Cuthbertson, D., Gowda, V., Hunt, K., Liu, S., Malloy, J., McCarthy, C., McLeod, W., Moyers, S., Nallamshetty, L., Smith, S., Akolkar, B., Briese, T., Erlich, H., Johnson, S. B. & Oberste, S., Oct 1 2007, In : Diabetes Technology and Therapeutics. 9, 5, p. 460-472 13 p.

Research output: Contribution to journalArticle

Type 1 Diabetes Mellitus
Costs and Cost Analysis
Population
Polymerase Chain Reaction
HLA Antigens
16 Citations (Scopus)

A mixture model approach to the tests of concordance and discordance between two large-scale experiments with two-sample groups

Lai, Y., Adam, B. L., Podolsky, R. & She, J. X., May 15 2007, In : Bioinformatics. 23, 10, p. 1243-1250 8 p.

Research output: Contribution to journalArticle

Concordance
Microarrays
Mixture Model
Parameter estimation
Mass spectrometry
1 Citation (Scopus)
Sjogren's Syndrome
Microarray Analysis