If you made any changes in Pure these will be visible here soon.

Research Output

2008

The IL-10 and IFN-γ pathways are essential to the potent immunosuppressive activity of cultured CD8+ NKT-like cells

Zhou, L., Wang, H., Zhong, X., Jin, Y., Mi, Q. S., Sharma, A. K., McIndoe, R. A., Garge, N., Podolsky, R. & She, J-X., Jul 29 2008, In : Genome Biology. 9, 7, R119.

Research output: Contribution to journalArticle

11 Scopus citations

Type 1 diabetes patients have significantly lower frequency of plasmacytoid dendritic cells in the peripheral blood

Chen, X., Makala, L. H. C., Jin, Y., Hopkins, D., Muir, A., Garge, N., Podolsky, R. H. & She, J. X., Dec 1 2008, In : Clinical Immunology. 129, 3, p. 413-418 6 p.

Research output: Contribution to journalArticle

34 Scopus citations
2007

A high-throughput population screening system for the estimation of genetic risk for type 1 diabetes: An application for the TEDDY (The Environmental Determinants of Diabetes in the Young) study

Kiviniemi, M., Hermann, R., Nurmi, J., Ziegler, A. G., Knip, M., Simell, O., Veijola, R., Lövgren, T., Ilonen, J., Rewers, M., Barriga, K., Baxter, J., Deas, A., Eisenbarth, G., Emery, L., Gesualdo, P., Hoffman, M., Norris, J., Waugh, K., Weber, S. & 88 others, She, J-X., Muir, A., Schatz, D., Hopkins, D., Steed, L., Choate, A., Silvis, K., Shankar, M., Huang, Y. H., Yang, P., Zheng, W. P., Wang, H. J., English, K., McIndoe, R. A., Bonifacio, E., Baumgarten, A., Hummel, S., Kersting, M., Koenig, S., Knopff, A., Locher, A., Roth, R., Schoen, S., Schwaiger, P., Sichert-Hellert, W., Winkler, C., Zimmermann, D., Nanto-Salonen, K., Simell, T., Uusitalo, U., Hyöty, H., Virtanen, S. M., Kronberg-Kippilä, C., Torma, M., Ruohonen, E., Romo, M., Mantymaki, E., Niininen, T., Nyblom, M., Stenius, A., Lernmark, Å., Almgren, P., Andrén-Aronsson, C., Andersson, E., Bianconi-Svensson, S., Carlsson, U. M., Cilio, C., Gerardsson, J., Gustavsson, B., Hansson, A., Hansson, G., Hansson, I., Ivarsson, S., Larsson, H., Karlsson, E., Katsarou, A., Lernmark, B., Massadakis, T., Nilsson, A., Järvirova, M. S., Sjöberg, B., Wallin, A., Wimar, Å., Hagopian, W. A., Brantley, M., Cowen, C., Hui, P., Hay, K. M., Jackson, M., Stepikova, V., Ugale, J., Krischer, J. P., Bray, C., Cuthbertson, D., Gowda, V., Hunt, K., Liu, S., Malloy, J., McCarthy, C., McLeod, W., Moyers, S., Nallamshetty, L., Smith, S., Akolkar, B., Briese, T., Erlich, H., Johnson, S. B. & Oberste, S., Oct 1 2007, In : Diabetes Technology and Therapeutics. 9, 5, p. 460-472 13 p.

Research output: Contribution to journalArticle

44 Scopus citations

A mixture model approach to the tests of concordance and discordance between two large-scale experiments with two-sample groups

Lai, Y., Adam, B. L., Podolsky, R. & She, J. X., May 15 2007, In : Bioinformatics. 23, 10, p. 1243-1250 8 p.

Research output: Contribution to journalArticle

16 Scopus citations
1 Scopus citations

GCSF receptor regulates antigen uptake and expression of cytokines and costimulatory molecules in dendritic cells

Geng, D., Joshi, S. K., Podolsky, R. & She, J. X., Jan 1 2007, In : Molecular Immunology. 44, 4, p. 521-529 9 p.

Research output: Contribution to journalArticle

7 Scopus citations

Gene amplification and associated loss of 5′ regulatory sequences of CoAA in human cancers

Sui, Y., Yang, Z., Xiong, S., Zhang, L., Blanchard, K. L., Peiper, S. C., Dynan, W. S., Tuan, D. & Ko, L., Feb 8 2007, In : Oncogene. 26, 6, p. 822-835 14 p.

Research output: Contribution to journalArticle

20 Scopus citations

Genetic factors for human type 1 diabetes

Wang, C. Y., Han, J. & She, J-X., Jan 1 2007, Current Topics in Human Genetics: Studies in Complex Diseases. World Scientific Publishing Co., p. 693-706 14 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations

Relative predispositional effects of HLA class II DRB1-DQB1 haplotypes and genotypes on type 1 diabetes: A meta-analysis

Thomson, G., Valdes, A. M., Noble, J. A., Kockum, I., Grote, M. N., Najman, J., Erlich, H. A., Cucca, F., Pugliese, A., Steenkiste, A., Dorman, J. S., Caillat-Zucman, S., Hermann, R., Ilonen, J., Lambert, A. P., Bingley, P. J., Gillespie, K. M., Lernmark, Å., Sanjeevi, C. B., Rønningen, K. S. & 32 others, Undlien, D. E., Thorsby, E., Petrone, A., Buzzetti, R., Koeleman, B. P. C., Roep, B. O., Saruhan-Direskeneli, G., Uyar, F. A., Günoz, H., Gorodezky, C., Alaez, C., Boehm, B. O., Mlynarski, W., Ikegami, H., Berrino, M., Fasano, M. E., Dametto, E., Israel, S., Brautbar, C., Santiago-Cortes, A., Frazer De Llado, T., She, J-X., Bugawan, T. L., Rotter, J. I., Raffel, L., Zeidler, A., Leyva-Cobian, F., Hawkins, B. R., Chan, S. H., Castano, L., Pociot, F. & Nerup, J., Aug 2007, In : Tissue Antigens. 70, 2, p. 110-127 18 p.

Research output: Contribution to journalArticle

114 Scopus citations

The autoimmune regulator directly controls the expression of genes critical for thymic epithelial function

Ruan, Q. G., Tung, K., Elsenman, D., Setiady, Y., Eckenrode, S., Yi, B., Purohit, S. B., Zheng, W. P., Zhang, Y., Peltonen, L. & She, J-X., Jun 1 2007, In : Journal of Immunology. 178, 11, p. 7173-7180 8 p.

Research output: Contribution to journalArticle

38 Scopus citations

The Environmental Determinants of Diabetes in the Young (TEDDY) study: Study design

Krischer, J., Rewers, M., Barriga, K., Baxter, J., Deas, A., Eisenbarth, G., Emery, L., Gesualdo, P., Hoffman, M., Norris, J., Waugh, K., Weber, S., She, J-X., Muir, A., Schatz, D., Hopkins, D., Steed, L., Silvis, K., Shankar, M., huang, Y. H. & 84 others, Yang, P., Zheng, W. P., Wang, H. J., English, K., McIndoe, R. A., Ziegler, A. G., Bonifacio, E., Baumgarten, A., Hummel, S., Kersting, M., Koenig, S., Knopff, A., Locher, A., Roth, R., Schoen, S., Schwaiger, P., Sichert-Hellert, W., Winkler, C., Zimmermann, D., Simell, O. G., Nanto-Salonen, K., Ilonen, J., Knip, M., Veijola, R., Simell, T., Uusitalo, U., Hyöty, H., Virtanen, S. M., Kronberg-Kippila̧, C., Torma, M., Ruohonen, E., Romo, M., Mantymaki, E., Niininen, T., Nyblom, M., Stenius, A., Lernmark, Å., Almgren, P., Andrén-Aronsson, C., Andersson, E., Bianconi-Svensson, S., Carlsson, U. M., Cilio, C., Gerardsson, J., Gustavsson, B., Hansson, A., Hansson, G., Hansson, I., Ivarsson, S., Larsson, H., Karlsson, E., Katsarou, A., Lernmark, B., Massadakis, T., Nilsson, A., Järvirova, M. S., Sjöberg, B., Wallin, A., Wimar, Å., Hagopian, W. A., Brantley, M., Cowen, C., Hui, P., Hay, K. M., Jackson, M., Stepikova, V., Ugale, J., Krischer, J. P., Bray, C., Cuthbertson, D., Gowda, V., Hunt, K., Liu, S., Malloy, J., McCarthy, C., McLeod, W., Moyers, S., Nallamshetty, L., Smith, S., Akolkar, B., Briese, T., Erlich, H., Bennett Johnson, S. & Oberste, S., Oct 1 2007, In : Pediatric Diabetes. 8, 5, p. 286-298 13 p.

Research output: Contribution to journalArticle

182 Scopus citations

Vascular endothelium summary statement VI: Research directions for the 21st century

Mensah, G. A., Catravas, J. D., Engelgau, M. M., Hooper, W. C., Madeddu, P., Ryan, U. S., She, J. X., Reed, E., Vinicor, F. & Yacoub, M. H., May 2007, In : Vascular Pharmacology. 46, 5 SPEC. ISS., p. 330-332 3 p.

Research output: Contribution to journalArticle

5 Scopus citations
2006

Assessing the utility of SELDI-TOF and model averaging for serum proteomic biomarker discovery

Purohit, S. B., Podolsky, R., Schatz, D., Muir, A., Hopkins, D., Huang, Y. H. & She, J-X., Dec 1 2006, In : Proteomics. 6, 24, p. 6405-6415 11 p.

Research output: Contribution to journalArticle

30 Scopus citations

Association of the PTPN22/LYP gene with type 1 diabetes

Steck, A. K., Liu, S. Y., McFann, K., Barriga, K. J., Babu, S. R., Eisenbarth, G. S., Rewers, M. J. & She, J. X., Oct 1 2006, In : Pediatric Diabetes. 7, 5, p. 274-278 5 p.

Research output: Contribution to journalArticle

45 Scopus citations

Characterization of PAF-AH Ib1 in NOD mice: PAF-AH may not be a candidate gene of the diabetes susceptibility Idd4.1 locus

Mi, Q. S., Zhou, L., Grattan, M., Wang, Z. Z., Sivilotti, M., She, J-X. & Delovitch, T. L., Oct 2006, Immunology of Diabetes IV: Progress in Our Understanding. Blackwell Publishing Inc., p. 147-152 6 p. (Annals of the New York Academy of Sciences; vol. 1079).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Disordered osteoclast formation in RAGE-deficient mouse establishes an essential role for RAGE in diabetes related bone loss

Ding, K., Wang, Z. Z., Hamrick, M. W., Deng, Z. B., Zhou, L., Kang, B., Yan, S. L., She, J-X., Stern, D. M., Isales, C. M. & Mi, Q. S., Feb 24 2006, In : Biochemical and Biophysical Research Communications. 340, 4, p. 1091-1097 7 p.

Research output: Contribution to journalArticle

87 Scopus citations

Early pathogenic events associated with Sjögren's syndrome (SjS)-like disease of the nod mouse using microarray analysis

Killedar, S. Y., Eckenrode, S. E., McIndoe, R. A., She, J. X., Nguyen, C. Q., Peck, A. B. & Cha, S. R., Dec 2 2006, In : Laboratory Investigation. 86, 12, p. 1243-1260 18 p.

Research output: Contribution to journalArticle

46 Scopus citations

Erratum (Retracted article): The autoimmune regulator (Aire) controls iNKT cell development and maturation (Nature Medicine (2006) 12 (624-626))

Mi, Q. S., Deng, Z. B., Joshi, S. K., Wang, Z. Z., Zhou, L., Eckenrode, S., Joshi, R., Ly, D., Yi, B., Delovitch, T. L. & She, J-X., Sep 1 2006, In : Nature Medicine. 12, 9, 1 p.

Research output: Contribution to journalComment/debate

1 Scopus citations

Genetic and functional evidence supporting SUMO4 as a type 1 diabetes susceptibility gene

Wang, C. Y., Podolsky, R. & She, J-X., Jan 1 2006, Immunology of Diabetes IV: Progress in Our Understanding. Blackwell Publishing Inc., p. 257-267 11 p. (Annals of the New York Academy of Sciences; vol. 1079).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

37 Scopus citations

Impaired Crkl expression contributes to the defective DNA binding of Stat5b in nonobese diabetic mice

Laloraya, M., Davoodi-Semiromi, A., Kumar, G. P., McDuffie, M. & She, J. X., Mar 2006, In : Diabetes. 55, 3, p. 734-741 8 p.

Research output: Contribution to journalArticle

16 Scopus citations

Maternal understanding of infant diabetes risk: Differential effects of maternal anxiety and depression

Hood, K. K., Johnson, S. B., Baughcum, A. E., She, J-X. & Schatz, D. A., Oct 1 2006, In : Genetics in Medicine. 8, 10, p. 665-670 6 p.

Research output: Contribution to journalArticle

9 Scopus citations

Physiologic self antigens rapidly capacitate autoimmune disease-specific polyclonal CD4+CD25+ regulatory T cells

Setiady, Y. Y., Ohno, K., Samy, E. T., Bagavant, H., Qiao, H., Sharp, C., Jin, X. S. & Tung, K. S. K., Feb 1 2006, In : Blood. 107, 3, p. 1056-1062 7 p.

Research output: Contribution to journalArticle

48 Scopus citations

TEDDY - The Environmental Determinants of Diabetes in the Young: An observational clinical trial

Hagopian, W. A., Lernmark, Å., Rewers, M. J., Simell, O. G., She, J. X., Ziegler, A. G., Krischer, J. P. & Akolkar, B., Oct 2006, Immunology of Diabetes IV: Progress in Our Understanding. Blackwell Publishing Inc., p. 320-326 7 p. (Annals of the New York Academy of Sciences; vol. 1079).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

71 Scopus citations

The application of genomic and proteomic technologies in predictive, preventive and personalized medicine

Collins, C. D., Purohit, S., Podolsky, R. H., Zhao, H. S., Schatz, D., Eckenrode, S. E., Yang, P., Hopkins, D., Muir, A., Hoffman, M., McIndoe, R. A., Rewers, M. & She, J. X., Nov 1 2006, In : Vascular Pharmacology. 45, 5, p. 258-267 10 p.

Research output: Contribution to journalArticle

47 Scopus citations

The autoimmune regulator (Aire) controls iNKT cell development and maturation

Mi, Q. S., Deng, Z. B., Joshi, S. K., Wang, Z. Z., Zhou, L., Eckenrode, S., Joshi, R., Ly, D., Yi, B., Delovitch, T. L. & She, J-X., Jun 1 2006, In : Nature Medicine. 12, 6, p. 624-626 3 p.

Research output: Contribution to journalArticle

6 Scopus citations

The autoimmune regulator (Aire) controls iNKT cell development and maturation.

Mi, Q. S., Deng, Z. B., Joshi, S. K., Wang, Z. Z., Zhou, L., Eckenrode, S., Joshi, R., Ly, D., Yi, B., Delovitch, T. L. & She, J. X., Sep 1 2006, In : Nature Medicine. 12, 9

Research output: Contribution to journalArticle

2005

Alterations of renal phenotype and gene expression profiles due to protein overload in NOD-related mouse strains

Wilson, K. H. S., McIndoe, R. A., Eckenrode, S., Morel, L., Agarwal, A., Croker, B. P. & She, J. X., Dec 21 2005, In : BMC Nephrology. 6, 17.

Research output: Contribution to journalArticle

6 Scopus citations

Autoimmunity to glutamic acid decarboxylase in the neurodegenerative disorder Batten disease

Ramirez-Montealegre, D., Chattopadhyay, S., Curran, T. M., Wasserfall, C., Pritchard, L., Schatz, D., Petitto, J., Hopkins, D., She, J. X., Rothberg, P. G., Atkinson, M. & Pearce, D. A., Feb 22 2005, In : Neurology. 64, 4, p. 743-745 3 p.

Research output: Contribution to journalArticle

24 Scopus citations

Chronic inflammatory demyelinating polyradiculoneuropathy in two children with type 1 diabetes mellitus

Fudge, E., Carol, J., She, J. X., Dosch, M., Atkinson, M. & Muir, A., Dec 1 2005, In : Pediatric Diabetes. 6, 4, p. 244-248 5 p.

Research output: Contribution to journalArticle

8 Scopus citations

Depressive symptoms in mothers of infants identified as genetically at risk for type 1 diabetes

Hood, K. K., Johnson, S. B., Carmichael, S. K., Laffel, L. M. B., She, J-X. & Schatz, D. A., Aug 1 2005, In : Diabetes Care. 28, 8, p. 1898-1903 6 p.

Research output: Contribution to journalArticle

15 Scopus citations

Genetic association between a lymphoid tyrosine phosphatase (PTPN22) and type 1 diabetes

Zheng, W. & She, J. X., Mar 1 2005, In : Diabetes. 54, 3, p. 906-908 3 p.

Research output: Contribution to journalArticle

113 Scopus citations

In reply [5]

Wang, C. Y., Yang, P. & She, J. X., Feb 1 2005, In : Nature Genetics. 37, 2, p. 112-113 2 p.

Research output: Contribution to journalLetter

3 Scopus citations

Lack of correlation between the levels of soluble cytotoxic T-lymphocyte associated antigen-4 (CTLA-4) and the CT-60 genotypes

Purohit, S., Podolsky, R., Collins, C., Zheng, W., Schatz, D., Muir, A., Hopkins, D., Huang, Y. H. & She, J. X., Oct 31 2005, In : Journal of Autoimmune Diseases. 2, 8.

Research output: Contribution to journalArticle

51 Scopus citations

Mapping DNA-binding domains of the autoimmune regulator protein

Purohit, S. B., Kumar, P. G., Laloraya, M. & She, J-X., Feb 18 2005, In : Biochemical and Biophysical Research Communications. 327, 3, p. 939-944 6 p.

Research output: Contribution to journalArticle

38 Scopus citations

Maternal efforts to prevent type 1 diabetes in at-risk children

Baughcum, A. E., Johnson, S. B., Carmichael, S. K., Lewin, A. B., She, J-X. & Schatz, D. A., Apr 1 2005, In : Diabetes Care. 28, 4, p. 916-921 6 p.

Research output: Contribution to journalReview article

20 Scopus citations
22 Scopus citations

Proteomic analysis of SUMO4 substrates in HEK293 cells under serum starvation-induced stress

Guo, D., Han, J., Adam, B. L., Colburn, N. H., Wang, M-H., Dong, Z., Eizirik, D. L., She, J-X. & Wang, C. Y., Dec 2 2005, In : Biochemical and Biophysical Research Communications. 337, 4, p. 1308-1318 11 p.

Research output: Contribution to journalArticle

69 Scopus citations

SUMO wrestling with type 1 diabetes

Li, M., Guo, D., Isales, C. M., Eizirik, D. L., Atkinson, M., She, J. X. & Wang, C. Y., Jul 1 2005, In : Journal of Molecular Medicine. 83, 7, p. 504-513 10 p.

Research output: Contribution to journalReview article

71 Scopus citations
2004

A functional variant of SUMO4, a new IκBα modifier, is associated with type diabetes

Guo, D., Li, M., Zhang, Y., Yang, P., Eckenrode, S., Hopkins, D., Zheng, W., Purohit, S. B., Podolsky, R. H., Muir, A., Wang, J., Dong, Z., Brusko, T., Atkinson, M., Pozzilli, P., Zeidler, A., Raffel, L. J., Jacob, C. O., Park, Y., Serrano-Rios, M. & 7 others, Martinez Larrad, M. T., Zhang, Z., Garchon, H. J., Bach, J. F., Rotter, J. I., She, J-X. & Wang, C. Y., Aug 1 2004, In : Nature Genetics. 36, 8, p. 837-841 5 p.

Research output: Contribution to journalArticle

299 Scopus citations

A Mutant Stat5b with Weaker DNA Binding Affinity Defines a Key Defective Pathway in Nonobese Diabetic Mice

Davoodi-Semiromi, A., Laloraya, M., Kumar, G. P., Purohit, S., Jha, R. K. & She, J. X., Mar 19 2004, In : Journal of Biological Chemistry. 279, 12, p. 11553-11561 9 p.

Research output: Contribution to journalArticle

32 Scopus citations

Autoimmune polyglandular syndrome type 1 and the autoimmune regulator

Ruan, Q. G. & She, J-X., Mar 1 2004, In : Clinics in Laboratory Medicine. 24, 1, p. 305-317 13 p.

Research output: Contribution to journalReview article

16 Scopus citations

Erratum: A functional variant of SUMO4, a new IκBα modifier, is associated with type 1 diabetes (Nature Genetics (2004) 36 (837-841))

Guo, D., Li, M., Zhang, Y., Yang, P., Eckenrode, S., Hopkins, D., Zheng, W., Purohit, S. B., Podolsky, R. H., Muir, A., Wang, J., Dong, Z., Brusko, T., Atkinson, M., Pozzilli, P., Zeidler, A., Raffel, L. J., Jacob, C. O., Park, Y., Serrano-Rios, M. & 7 others, Martinez Larrad, M. T., Zhang, Z., Garchon, H. J., Bach, J. F., Rotter, J. I., She, J-X. & Wang, C. Y., Sep 2004, In : Nature Genetics. 36, 9, 1 p.

Research output: Contribution to journalComment/debate

Open Access

Gene Expression Profiles Define a Key Checkpoint for Type 1 Diabetes in NOD Mice

Eckenrode, S. E., Ruan, Q., Yang, P., Zheng, W., McIndoe, R. A. & She, J-X., Feb 1 2004, In : Diabetes. 53, 2, p. 366-375 10 p.

Research output: Contribution to journalArticle

27 Scopus citations

Maternal Anxiety Associated with Newborn Genetic Screening for Type 1 Diabetes

Johnson, S. B., Baughcum, A. E., Carmichael, S. K., She, J-X. & Schatz, D. A., Feb 1 2004, In : Diabetes Care. 27, 2, p. 392-397 6 p.

Research output: Contribution to journalArticle

33 Scopus citations

Microarray experimental design: Power and sample size considerations

Yang, M. C. K., Yang, J. J., McIndoe, R. A. & She, J. X., Apr 1 2004, In : Physiological Genomics. 16, p. 24-28 5 p.

Research output: Contribution to journalArticle

40 Scopus citations

Molecular cloning and characterization of the mouse Acdp gene family

Wang, C. Y., Yang, P., Shi, J. D., Purohit, S., Guo, D., An, H., Gu, J. G., Ling, J., Dong, Z. & She, J. X., Jan 15 2004, In : BMC Genomics. 5, 7.

Research output: Contribution to journalArticle

37 Scopus citations

Molecular pathways altered by insulin B9-23 immunization

Eckenrode, S. E., Ruan, Q. G., Collins, C. D., Yang, P., McIndoe, R. A., Muir, A. & She, J-X., Jan 1 2004, In : Annals of the New York Academy of Sciences. 1037, p. 175-185 11 p.

Research output: Contribution to journalArticle

4 Scopus citations

Novel TSHβ subunit gene mutation causing congenital central hypothyroidism in a newborn male

Morales, A. E., Shi, J. D., Wang, C. Y., She, J. X. & Muir, A., Jan 1 2004, In : Journal of Pediatric Endocrinology and Metabolism. 17, 3, p. 355-359 5 p.

Research output: Contribution to journalArticle

14 Scopus citations

Prenatal and infant nutrition in the pathogenesis of type 1 diabetes implications for diagnosis and therapy

Muir, A. & She, J-X., Jan 1 2004, Perinatal Nutrition: Optimizing Infant Health and Development. CRC Press, p. 307-330 24 p.

Research output: Chapter in Book/Report/Conference proceedingChapter