If you made any changes in Pure, your changes will be visible here soon.

Research Output 1987 2019

2010
1 Citation (Scopus)

Erratum: Loss-of-function mutations in HPSE2 cause the autosomal recessive urofacial syndrome (The American Journal of Human Genetics (2010) 86 (957-962))

Pang, J., Zhang, S., Yang, P., Lee, B. H., Zhong, J., Zhang, Y., Ochoa, B., Agundez, J. A. G., Voelckel, M. A., Fisher, R. B., Gu, W., Xiong, W., Mei, L., She, J-X. & Wang, C. Y., Jul 9 2010, In : American Journal of Human Genetics. 87, 1, 1 p.

Research output: Contribution to journalComment/debate

Medical Genetics
Mutation
Urofacial syndrome
24 Citations (Scopus)

Genetically dependent ERBB3 expression modulates antigen presenting cell function and type 1 diabetes risk

Wang, H., Jin, Y., Reddy, M. V. P. L., Podolsky, R., Liu, S., Yang, P., Bode, B., Reed, J. C., Steed, R. D., Anderson, S. W., Steed, L., Hopkins, D., Huang, Y. & She, J-X., Aug 20 2010, In : PloS one. 5, 7, e11789.

Research output: Contribution to journalArticle

antigen-presenting cells
insulin-dependent diabetes mellitus
Antigen-Presenting Cells
Medical problems
Type 1 Diabetes Mellitus
19 Citations (Scopus)

Hepatic gene expression profiling reveals key pathways involved in leptin-mediated weight loss in ob/ob mice

Sharma, A., Bartell, S. M., Baile, C. A., Chen, B., Podolsky, R. H., McIndoe, R. A. & She, J. X., Oct 20 2010, In : PloS one. 5, 8, e12147.

Research output: Contribution to journalArticle

Gene Expression Profiling
Leptin
leptin
Gene expression
Weight Loss
41 Citations (Scopus)

Loss-of-Function Mutations in HPSE2 Cause the Autosomal Recessive Urofacial Syndrome

Pang, J., Zhang, S., Yang, P., Lee, B. H., Zhong, J., Zhang, Y., Ochoa, B., Agundez, J. A. G., Voelckel, M. A., Gu, W., Xiong, W., Mei, L., She, J-X. & Wang, C. Y., Jul 11 2010, In : American journal of human genetics. 86, 6, p. 957-962 6 p.

Research output: Contribution to journalArticle

Mutation
Genes
Facial Expression
Colombia
Hydrolases
86 Citations (Scopus)

MicroRNA-34a is induced via p53 during cisplatin nephrotoxicity and contributes to cell survival

Bhatt, K., Zhou, L., Mi, Q. S., Huang, S., She, J-X. & Dong, Z., Sep 1 2010, In : Molecular Medicine. 16, 9-10, p. 409-416 8 p.

Research output: Contribution to journalArticle

MicroRNAs
Cisplatin
Cell Survival
Acute Kidney Injury
Kidney
39 Citations (Scopus)

Porous-wall hollow glass microspheres as novel potential nanocarriers for biomedical applications

Li, S., Nguyen, L., Xiong, H., Wang, M., Hu, T. C. C., She, J-X., Serkiz, S. M., Wicks, G. G. & Dynan, W. S., Jan 1 2010, In : Nanomedicine: Nanotechnology, Biology, and Medicine. 6, 1, p. 127-136 10 p.

Research output: Contribution to journalArticle

Microspheres
Glass
Antibodies
Single-Chain Antibodies
Immunoglobulin Fragments
6 Citations (Scopus)

Proficiency testing of human leukocyte antigen-DR and human leukocyte antigen-DQ genetic risk assessment for type 1 diabetes using dried blood spots

Dantonio, P., Meredith-Molloy, N., Hagopian, W. A., She, J. X., Akolkar, B., Cordovado, S. K., Hendrix, M., Henderson, L. O., Hannon, W. H. & Vogt, R. F., Jul 2010, In : Journal of Diabetes Science and Technology. 4, 4, p. 929-941 13 p.

Research output: Contribution to journalArticle

Antigens
Medical problems
HLA Antigens
Type 1 Diabetes Mellitus
Risk assessment
33 Citations (Scopus)

Proteomic technologies for the discovery of type 1 diabetes biomarkers

Zhi, W., Purohit, S., Carey, C., Wang, M. & She, J. X., Jul 2010, In : Journal of Diabetes Science and Technology. 4, 4, p. 993-1002 10 p.

Research output: Contribution to journalReview article

Biomarkers
Medical problems
Type 1 Diabetes Mellitus
Proteomics
Technology
2011
55 Citations (Scopus)

Association between type 1 diabetes and GWAS SNPs in the southeast US Caucasian population

Reddy, M. P. L., Wang, H., Liu, S., Bode, B., Reed, J. C., Steed, R. D., Anderson, S. W., Steed, L., Hopkins, D. & She, J-X., Apr 1 2011, In : Genes and Immunity. 12, 3, p. 208-212 5 p.

Research output: Contribution to journalArticle

Southeastern United States
Genome-Wide Association Study
Type 1 Diabetes Mellitus
Single Nucleotide Polymorphism
Interleukin-27
98 Citations (Scopus)

Central (ICV) leptin injection increases bone formation, bone mineral density, muscle mass, serum IGF-1, and the expression of osteogenic genes in leptin-deficient ob/ob mice

Bartell, S. M., Rayalam, S., Ambati, S., Gaddam, D. R., Hartzell, D. L., Hamrick, M. W., She, J-X., Della-Fera, M. A. & Baile, C. A., Aug 1 2011, In : Journal of Bone and Mineral Research. 26, 8, p. 1710-1720 11 p.

Research output: Contribution to journalArticle

Leptin
Insulin-Like Growth Factor I
Osteogenesis
Bone Density
Gene Expression
16 Citations (Scopus)

Chemokine (c-c motif) ligand 2 (ccl2) in sera of patients with type 1 diabetes and diabetic complications

Guan, R., Purohit, S. B., Wang, H., Bode, B., Reed, J. C., Steed, R. D., Anderson, S. W., Steed, L., Hopkins, D., Xia, C. & She, J-X., Apr 21 2011, In : PloS one. 6, 4, e17822.

Research output: Contribution to journalArticle

insulin-dependent diabetes mellitus
Chemokine CCL2
Diabetes Complications
Medical problems
Type 1 Diabetes Mellitus
5 Citations (Scopus)

Country-specific birth weight and length in type 1 diabetes high-risk HLA genotypes in combination with prenatal characteristics

Sterner, Y., Törn, C., Lee, H. S., Larsson, H., Winkler, C., McLeod, W., Lynch, K., Simell, O., Ziegler, A., Schatz, D., Hagopian, W., Rewers, M., She, J. X., Krischer, J. P., Akolkar, B. & Lernmark, Å., Dec 1 2011, In : Journal of Perinatology. 31, 12, p. 764-769 6 p.

Research output: Contribution to journalArticle

HLA Antigens
Type 1 Diabetes Mellitus
Birth Weight
Genotype
Parturition
11 Citations (Scopus)

Delineating the angiogenic gene expression profile before pulmonary vascular remodeling in a lamb model of congenital heart disease

Tian, J., Fratz, S., Hou, Y., Lu, Q., Görlach, A., Hess, J., Schreiber, C., Datar, S. A., Oishi, P., Nechtman, J., Podolsky, R., She, J-X., Fineman, J. R. & Black, S. M., Jan 1 2011, In : Physiological Genomics. 43, 2, p. 87-98 12 p.

Research output: Contribution to journalArticle

Transcriptome
Heart Diseases
Lung
Fibroblast Growth Factor 2
Genes

Developments in small molecule immunosuppressive drugs

Liu, Y., Wang, Y. B., Zhang, Q. & She, J-X., Oct 30 2011, In : Chinese Journal of New Drugs. 20, 20, p. 1981-1988 8 p.

Research output: Contribution to journalReview article

Immunosuppressive Agents
Pharmaceutical Preparations
Janus Kinase 3
Tacrolimus
Organ Transplantation
37 Citations (Scopus)

Discovery and validation of serum protein changes in type 1 diabetes patients using high throughput two dimensional liquid chromatography-mass spectrometry and immunoassays.

Zhi, W., Sharma, A., Purohit, S., Miller, E., Bode, B., Anderson, S. W., Reed, J. C., Steed, R. D., Steed, L., Hopkins, D. & She, J. X., Nov 1 2011, In : Molecular & cellular proteomics : MCP. 10, 11

Research output: Contribution to journalArticle

Liquid chromatography
Medical problems
Type 1 Diabetes Mellitus
Immunoassay
Liquid Chromatography
8 Citations (Scopus)
Inbred NOD Mouse
Focal Adhesions
Gene Expression Profiling
Lacrimal Apparatus
Leukocytes
4 Citations (Scopus)

Lack of an association of miR-938 SNP in IDDM10 with human type 1 diabetes

Mi, X., He, H., Deng, Y., Levin, A. M., She, J-X., Mi, Q. S. & Zhou, L., Oct 21 2011, In : Diabetology and Metabolic Syndrome. 3, 1, 27.

Research output: Contribution to journalArticle

Type 1 Diabetes Mellitus
Single Nucleotide Polymorphism
MicroRNAs
Interleukin-16
Small Untranslated RNA
74 Citations (Scopus)

Reduced serum vitamin D-binding protein levels are associated with type 1 diabetes

Blanton, D., Han, Z., Bierschenk, L., Linga-Reddy, M. V. P., Wang, H., Clare-Salzler, M., Haller, M., Schatz, D., Myhr, C., She, J-X., Wasserfall, C. & Atkinson, M., Oct 1 2011, In : Diabetes. 60, 10, p. 2566-2570 5 p.

Research output: Contribution to journalArticle

Vitamin D-Binding Protein
Type 1 Diabetes Mellitus
Blood Proteins
Vitamin D
Single Nucleotide Polymorphism
18 Citations (Scopus)
Isotopes
Labeling
Mass spectrometry
Monitoring
Assays

Synthesis of saracatinib

Shang, H. F., Wang, Y. B., Zhao, D. M., Zhang, Q. & She, J-X., Dec 15 2011, In : Chinese Journal of New Drugs. 20, 23, p. 2363-2366 4 p.

Research output: Contribution to journalArticle

src-Family Kinases
Cyclization
Hydrolysis
saracatinib
Proton Magnetic Resonance Spectroscopy
112 Citations (Scopus)

The Environmental Determinants of Diabetes in the Young (TEDDY): Genetic criteria and international diabetes risk screening of 421 000 infants

Hagopian, W. A., Erlich, H., Lernmark, Å., Rewers, M., Ziegler, A. G., Simell, O., Akolkar, B., Vogt, R., Blair, A., Ilonen, J., Krischer, J. & She, J., Dec 1 2011, In : Pediatric Diabetes. 12, 8, p. 733-743 11 p.

Research output: Contribution to journalArticle

HLA Antigens
Type 1 Diabetes Mellitus
Costs and Cost Analysis
Population
Genotyping Techniques
2012
28 Citations (Scopus)

Confirmation of novel type 1 diabetes risk loci in families

Cooper, J. D., Howson, J. M. M., Smyth, D., Walker, N. M., Stevens, H., Yang, J. H. M., She, J-X., Eisenbarth, G. S., Rewers, M., Todd, J. A., Akolkar, B., Concannon, P., Erlich, H. A., Julier, C., Morahan, G., Nerup, J., Nierras, C., Pociot, F. & Rich, S. S., Apr 1 2012, In : Diabetologia. 55, 4, p. 996-1000 5 p.

Research output: Contribution to journalArticle

Type 1 Diabetes Mellitus
Genome-Wide Association Study
Genotype
Genetic Association Studies
Population
3 Citations (Scopus)

Detection of lactobacilli in monthly mail-in stool samples from 3-18 months old infants at genetic risk for type 1 diabetes

Salami, F., Abels, M., Hyöty, H., Vaziri-Sani, F., Aronsson, C. A., Vehik, K., Delli, A., Hagopian, W. A., Rewers, M., Ziegler, A. G., Simell, O., Akolkar, B., Krischer, J., She, J-X. & Leramark, Å., Dec 1 2012, In : International Journal of Probiotics and Prebiotics. 7, 3-4, p. 135-144 10 p.

Research output: Contribution to journalArticle

insulin-dependent diabetes mellitus
Postal Service
Lactobacillus
Type 1 Diabetes Mellitus
Sweden
22 Citations (Scopus)

Differences in recruitment and early retention among ethnic minority participants in a large pediatric cohort: The TEDDY Study

Baxter, J., Vehik, K., Johnson, S. B., Lernmark, B., Roth, R., Simell, T., Rewers, M., Barriga, K., Bautista, K., Baxter, J., Eisenbarth, G., Frank, N., Gesualdo, P., Hoffman, M., Ide, L., Karban, R., Liu, E., Norris, J., Waugh, K., Samper-Imaz, A. & 149 others, Steck, A., She, J-X., Schatz, D., Hopkins, D., Steed, L., Thomas, J., Silvis, K., Haller, M., Shankar, M., English, K., McIndoe, R. A., Liu, H., Nechtman, J., Williams, J., Foghis, G., Stephen, W., Anderson, M. D., Ziegler, A. G., Achenbach, A., Boerschmann, H., Bonifacio, E., Bunk, M., Försch, J., Henneberger, L., Hummel, M., Hummel, S., Joslowski, G., Kersting, M., Knopff, A., Kocher, N., Koletzko, S., Krause, S., Mann, A., Matzke, C., Mittermeier, A., Peplow, C., Pflüger, M., Ramminger, C., Strauss, E., Rash-Sur, S., Roth, R., Schenkel, J., Stock, J., Voit, K., Winkler, C., Wosch, A., Zwilling, M., Simell, O. G., Nanto-Salonen, K., Ilonen, J., Knip, M., Tuula Simell, V., Hyöty, H., Virtanen, S. M., Kronberg-Kippilä, C., Sjöberg, M., Simell, B., Ruohonen, E., Romo, M., Mantymaki, E., Schroderus, H., Nyblom, M., Stenius, A., Lernmark, Å., Agardh, D., Almgren, P., Andersson, E., Andrén-Aronsson, C., Ask, M., Karlsson, U. M., Cilio, C., Bremer, J., Ericson-Hallström, E., Gard, T., Gerardsson, J., Hansson, G., Hansen, M., Hyberg, S., Håkansson, R., Johansen, F., Jonsson, L., Larsson, H., Lernmark, B., Markan, M., Massadakis, T., Melin, J., Månsson-Martinez, M., Nilsson, A., Rahmati, K., Järvirova, M. S., Sibthorpe, S., Sjöberg, B., Skogberg, A., Törn, C., Wallin, A., Wimar, Å., Åberg, S., Hagopian, W. A., Yan, X., Killian, M., Cowen Crouch, C., Hay, K. M., Ayres, S., Adams, C., Bratrude, B., Coughlin, D., Fowler, G., Franco, C., Hammar, C., Heaney, D., Marcus, P., Meyer, A., Mulenga, D., Scott, E., Skidmore, J., Stabbert, J., Stepitova, V., Williams, N., Becker, D., Franciscus, M., Dalmagro-Elias, M. E., Daftary, A., Krischer, J. P., Abbondondolo, M., Ballard, L., Brown, R., Burkhardt, B., Cuthbertson, D., Eberhard, C., Fiske, S., Gowda, V., Hadley, D., Lee, H. S., Liu, S., Lynch, K., Malloy, J., McCarthy, C., McLeod, W., Smith, L., Smith, S., Uusitalo, U., Vehik, K., Washington, E., Yang, J., Akolkar, B., Briese, T., Erlich, H., Johnson, S. B. & Oberste, S., Jul 1 2012, In : Contemporary Clinical Trials. 33, 4, p. 633-640 8 p.

Research output: Contribution to journalArticle

Type 1 Diabetes Mellitus
Pediatrics
Minority Groups
Hispanic Americans
Ethnic Groups
36 Citations (Scopus)

Evidence of gene-gene interaction and age-at-diagnosis effects in type 1 diabetes

Howson, J. M. M., Cooper, J. D., Smyth, D. J., Walker, N. M., Stevens, H., She, J. X., Eisenbarth, G. S., Rewers, M., Todd, J. A., Akolkar, B., Concannon, P., Erlich, H. A., Julier, C., Morahan, G., Nerup, J., Nierras, C., Pociot, F. & Rich, S. S., Nov 1 2012, In : Diabetes. 61, 11, p. 3012-3017 6 p.

Research output: Contribution to journalArticle

Type 1 Diabetes Mellitus
Genotype
Genes
Interleukin-2
CTLA-4 Antigen
5 Citations (Scopus)

Novel biomarkers in type 1 diabetes

Jin, Y. & She, J. X., Dec 1 2012, In : Review of Diabetic Studies. 9, 4, p. 224-235 12 p.

Research output: Contribution to journalReview article

Type 1 Diabetes Mellitus
Biomarkers
Autoantibodies
Proteomics
Genes
5 Citations (Scopus)
Inbred NOD Mouse
T-cells
Regulatory T-Lymphocytes
Medical problems
Up-Regulation
9 Citations (Scopus)
Insulin-Like Growth Factor Binding Protein 6
Diabetes Complications
Medical problems
Type 1 Diabetes Mellitus
Serum
2013
11 Citations (Scopus)

Delineation of biological and molecular mechanisms underlying the diverse anticancer activities of mycophenolic acid

Dun, B., Xu, H., Sharma, A. K., Liu, H., Yu, H., Yi, B., Liu, X., He, M., Zeng, L. & She, J-X., Dec 5 2013, In : International Journal of Clinical and Experimental Pathology. 6, 12, p. 2880-2886 7 p.

Research output: Contribution to journalArticle

Mycophenolic Acid
Cell Line
Apoptosis
Cell Proliferation
Neoplasms
4 Citations (Scopus)

Enhanced T Cell Lymphoma in NOD.Stat5b Transgenic Mice Is Caused by Hyperactivation of Stat5b in CD8+ Thymocytes

Chen, B., Yi, B., Mao, R., Liu, H., Wang, J., Sharma, A. K., Peiper, S., Leonard, W. J. & She, J-X., Feb 14 2013, In : PloS one. 8, 2, e56600.

Research output: Contribution to journalArticle

Phosphorylation
thymocytes
T-cells
T-Cell Lymphoma
Thymocytes
28 Citations (Scopus)

Methods, quality control and specimen management in an international multicentre investigation of type 1 diabetes: TEDDY

Vehik, K., Fiske, S. W., Logan, C. A., Agardh, D., Cilio, C. M., Hagopian, W., Simell, O., Roivainen, M., She, J-X., Briese, T., Oikarinen, S., Hyoty, H., Ziegler, A. G., Rewers, M., Lernmark, A., Akolkar, B., Krischer, J. P. & Burkhardt, B. R., Oct 1 2013, In : Diabetes/Metabolism Research and Reviews. 29, 7, p. 557-567 11 p.

Research output: Contribution to journalArticle

Type 1 Diabetes Mellitus
Quality Control
Biomarkers
Autoantibodies
Autoimmunity
17 Citations (Scopus)

Mycophenolic acid inhibits migration and invasion of gastric cancer cells via multiple molecular pathways

Dun, B., Sharma, A., Teng, Y., Liu, H., Purohit, S., Xu, H., Zeng, L. & She, J. X., Nov 15 2013, In : PloS one. 8, 11, e81702.

Research output: Contribution to journalArticle

Mycophenolic Acid
stomach neoplasms
Stomach Neoplasms
Genes
Cells
20 Citations (Scopus)

Next-generation sequencing for viruses in children with rapid-onset type 1 diabetes

Lee, H. S., Briese, T., Winkler, C., Rewers, M., Bonifacio, E., Hyoty, H., Pflueger, M., Simell, O., She, J. X., Hagopian, W., Lernmark, A., Akolkar, B., Krischer, J. P. & Ziegler, A. G., Aug 1 2013, In : Diabetologia. 56, 8, p. 1705-1711 7 p.

Research output: Contribution to journalArticle

Type 1 Diabetes Mellitus
Viruses
Autoimmunity
Fever
Viremia
8 Citations (Scopus)

Serum protein profile at remission can accurately assess therapeutic outcomes and survival for serous ovarian cancer

Wang, J., Sharma, A., Ghamande, S. A., Bush, S., Ferris, D., Zhi, W., He, M., Wang, M., Wang, X., Miller, E., Hopkins, D., Macfee, M., Guan, R., Tang, J. & She, J. X., Nov 11 2013, In : PloS one. 8, 11, e78393.

Research output: Contribution to journalArticle

ovarian neoplasms
remission
Ovarian Neoplasms
blood proteins
Blood Proteins
13 Citations (Scopus)

Systematic evaluation of 640 FDA drugs for their effect on CD4 +Foxp3+ regulatory T cells using a novel cell-based high throughput screening assay

Mao, R., Xiao, W., Liu, H., Chen, B., Yi, B., Kraj, P. & She, J-X., May 15 2013, In : Biochemical Pharmacology. 85, 10, p. 1513-1524 12 p.

Research output: Contribution to journalArticle

High-Throughput Screening Assays
T-cells
Regulatory T-Lymphocytes
Assays
Screening
16 Citations (Scopus)

The expression of inflammatory genes is upregulated in peripheral blood of patients with type 1 diabetes

Jin, Y., Sharma, A. K., Davis, C. M., Hopkins, D., Wang, X., Robertson, D. G., Bode, B., Anderson, S. W., Reed, J. C., Steed, R. D., Steed, L. & She, J-X., Sep 1 2013, In : Diabetes Care. 36, 9, p. 2794-2802 9 p.

Research output: Contribution to journalArticle

Type 1 Diabetes Mellitus
Gene Expression
Genes
Antigen Presentation
Myeloid Cells
2014
4 Citations (Scopus)

A novel monoclonal antibody induces cancer cell apoptosis and enhances the activity of chemotherapeutic drugs

Xu, H., Tian, Y. N., Dun, B. Y., Liu, H. T., Dong, G. K., Wang, J. H., Lu, S. S., Chen, B. & She, J. X., 2014, In : Asian Pacific Journal of Cancer Prevention. 15, 11, p. 4423-4428 6 p.

Research output: Contribution to journalArticle

Monoclonal Antibodies
Apoptosis
Carcinoma
Pharmaceutical Preparations
Neoplasms
14 Citations (Scopus)

Anti-angiogenic effect of auranofin on HUVECs in vitro and zebrafish in vivo

He, M. F., Gao, X. P., Li, S. C., He, Z. H., Chen, N., Wang, Y. B. & She, J-X., Jan 1 2014, In : European Journal of Pharmacology. 740, p. 240-247 8 p.

Research output: Contribution to journalArticle

Auranofin
Zebrafish
Vascular Endothelial Growth Factor A
Physiological Phenomena
Thioredoxin-Disulfide Reductase
14 Citations (Scopus)

Biomarker discovery study design for type 1 diabetes in The Environmental Determinants of Diabetes in the Young (TEDDY) study

Lee, H. S., Burkhardt, B. R., Mcleod, W., Smith, S., Eberhard, C., Lynch, K., Hadley, D., Rewers, M., Simell, O., She, J. X., Hagopian, B., Lernmark, A., Akolkar, B., Ziegler, A. G., Krischer, J. P., Barriga, K., Bautista, K., Baxter, J., Eisenbarth, G., Frank, N. & 208 others, Gesualdo, P., Hoffman, M., Ide, L., Karban, R., Liu, E., Norris, J., Waugh, K., Samper-Imaz, A., Steck, A., Schatz, D., Hopkins, D., Steed, L., Thomas, J., Silvis, K., Haller, M., Shankar, M., Sheehan, E., Gardiner, M., McIndoe, R., Liu, H., Nechtman, J., Sharma, A., Williams, J., Foghis, G., Anderson W., S. W., Beyerlein, A., Bonifacio, E., Hummel, M., Hummel, S., Foterek, K., Kersting, M., Knopff, A., Koletzko, S., Peplow, C., Roth, R., Schenke, J., Stock, J., Strauss, E., Warncke, K., Winkler, C., Simell G., O. G., Hyoty, H., Ilonen, J., Knip, M., Koivu, A., Koreasalo, M., Kahonen, M., Lonnrot, M., Multasuo, K., Mantymaki, E., Mykkanen, J., Nanto-Salonen, K., Niininen, T., Nyblom, M., Rautanen, J., Riikonen, A., Romo, M., Simell, A., Simell, B., Simell, T., Simell, V., Sjoberg, M., Stenius, A., Toppari, J., Varjonen, E., Veijola, R., Virtanen M., S. M., Akerlund, M., Agardh, D., Andrén-Aronsson, C., Ask, M., Bremer, J., Carlsson, U. M., Cilio, C., Ericson-Hallstrom, E., Fransson, L., Gard, T., Gerardsson, J., Hakansson, R., Hansen, M., Hansson, G., Hyberg, S., Johansen, F., Jonasdottir, B., Jonsson, L., Larsson, H., Lernmark, B., Mansson-Martinez, M., Markan, M., Massadakis, T., Melin, J., Mestan, Z., Nilsson, A., Nilsson, E., Rahmati, K., Rosenquist, A., Salami, F., Jarvirova, M. S., Sibthorpe, S., Sjoberg, B., Swartling, U., Trulsson, E., Torn, C., Wallin, A., Wimar, A., Aberg, S., Hagopian A., W. A., Yan, X., Killian, M., Crouch, C. C., Hay M., K. M., Ayres, S., Adams, C., Bratrude, B., Coughlin, D., Fowler, G., Franco, C., Hammar, C., Heaney, D., Marcus, P., Meyer, A., Mulenga, D., Scott, E., Skidmore, J., Stabbert, J., Stepitova, V., Williams, N., Becker, D., Franciscus, M., Dalmagro-Elias, M. E., Daftary, A., Klein, M. B., Abbondondolo, M., Austin-Gonzalez, S., Brown, R., Burkhardt, B., Butterworth, M., Cuthbertson, D., Eberhard, C., Fiske, S., Gowda, V., Lane, P., Liu, S., Liu, X., Malloy, J., McCarthy, C., McLeod, W., Smith, L., Tamura, R., Uusitalo, U., Vehik, K., Washington, E., Yang, J., Bourcier, K., Briese, T., Johnson, S. B., Oberste, S., Triplett, E., Yu, L., Miao, D., Bingley, P., Williams, A., Chandler, K., Rokni, S., Long, A., Boldison, J., Butterly, J., Broadhurst, J., Carreno, G., Curnock, R., Easton, P., Geoghan, I., Goode, J., Pearson, J., Reed, C., Ridewood, S., Wyatt, R., Eriksson, E. A., Karlsson, E. L., Erlund, I., Salminen, I., Sundvall, J., Leiviska, J., Lehtonen, M., Little R., R. R., Tennill L., A. L., Erlich, H., Bugawan, T., Alejandrino, M., Fiehn, O., Wikoff, B., Kind, T., Palazoglu, M., Wong, J., Wohlgemuth, G., Petrosino F., J. F., Marcovina M., S. M., Higgins, H., Ke, S., Zhao, Y., Jiang, N., Rich S., S. S., Chen, W. M., Onengut-Gumuscu, S., Farber, E., Pickin, R. R., Davis, J. & Gallo, D., Jul 2014, In : Diabetes/Metabolism Research and Reviews. 30, 5, p. 424-434 11 p.

Research output: Contribution to journalArticle

Type 1 Diabetes Mellitus
Biomarkers
Quality Control
Autoantibodies
Metagenomics
35 Citations (Scopus)

Children followed in the TEDDY study are diagnosed with type 1 diabetes at an early stage of disease

Elding Larsson, H., Vehik, K., Gesualdo, P., Akolkar, B., Hagopian, W., Krischer, J., Lernmark, Å., Rewers, M., Simell, O., She, J. X., Ziegler, A. & Haller, M. J., Mar 2014, In : Pediatric Diabetes. 15, 2, p. 118-126 9 p.

Research output: Contribution to journalArticle

Type 1 Diabetes Mellitus
Glutamate Decarboxylase
Class 8 Receptor-Like Protein Tyrosine Phosphatases
Glucose Tolerance Test
Autoantibodies
3 Citations (Scopus)

Pharmacophore-based discovery of new human dihydroorotate dehydrogenase inhibitor

Lu, P., Wang, Y., Ma, B., She, J., Zhang, Q., He, M. & Liu, Y., Jan 1 2014, In : Medicinal Chemistry. 10, 4, p. 402-408 7 p.

Research output: Contribution to journalArticle

Inhibitory Concentration 50
Chemical Databases
Random Allocation
Hydrogen
Costs and Cost Analysis
6 Citations (Scopus)

Prevalence of obesity was related to HLA-DQ in 2-4-year-old children at genetic risk for type 1 diabetes

Yang, J., Lernmark, Uusitalo, U. M., Lynch, K. F., Veijola, R., Winkler, C., Larsson, H. E., Rewers, M., She, J. X., Ziegler, A. G., Simell, O. G., Hagopian, W. A., Akolkar, B., Krischer, J. P. & Vehik, K., Dec 11 2014, In : International Journal of Obesity. 38, 12, p. 1491-1496 6 p.

Research output: Contribution to journalArticle

HLA Antigens
Type 1 Diabetes Mellitus
Obesity
Genotype
Body Size
18 Citations (Scopus)
Lymphocyte Activation
Type 1 Diabetes Mellitus
Autoantibodies
Genes
Gene Expression
14 Citations (Scopus)

Serum Dickkopf-1 (DKK1) is significantly lower in patients with lung cancer but is rapidly normalized after treatment

Xu, H., Wu, J., Chen, B., Li, M., Tian, Y., He, M., Xue, J., Wang, J., Bai, S., Sharma, A. K., Liu, H., Tang, J. & She, J-X., Jan 1 2014, In : American Journal of Translational Research. 6, 6, p. 850-856 7 p.

Research output: Contribution to journalArticle

Catenins
Lung Neoplasms
Serum
Cells
Non-Small Cell Lung Carcinoma
Thiadiazoles
Immunosuppressive Agents
formamide
benzofuran
4 Citations (Scopus)

Synthesis and in vitro evaluation of 1,3,4-thiadiazol-2-yl urea derivatives as novel AChE inhibitors

Xue, X. J., Wang, Y. B., Lu, P., Shang, H. F., She, J-X., Xia, L. X., Qian, H. & Huang, W. L., Jan 1 2014, In : Chemical and Pharmaceutical Bulletin. 62, 6, p. 524-527 4 p.

Research output: Contribution to journalArticle

Cholinesterase Inhibitors
Urea
Galantamine
Derivatives
Structure-Activity Relationship
12 Citations (Scopus)

Toxicity assessment of 7 anticancer compounds in zebrafish

Gao, X. P., Feng, F., Zhang, X. Q., Liu, X. X., Wang, Y. B., She, J-X., He, Z. H. & He, M. F., Jan 1 2014, In : International Journal of Toxicology. 33, 2, p. 98-105 8 p.

Research output: Contribution to journalArticle

Zebrafish
Mycophenolic Acid
Thalidomide
Toxicity
Paclitaxel
13 Citations (Scopus)

Transcriptomic changes induced by mycophenolic acid in gastric cancer cells

Dun, B., Sharma, A., Xu, H., Liu, H., Bai, S., Zeng, L. & She, J. X., 2014, In : American Journal of Translational Research. 6, 1, p. 28-42 15 p.

Research output: Contribution to journalArticle

Mycophenolic Acid
Stomach Neoplasms
Cells
Genes
Biological Phenomena
9 Citations (Scopus)
Squamous Cell Neoplasms
Serum Amyloid A Protein
Uterine Cervical Neoplasms
Blood Proteins
Carcinoembryonic Antigen
2015
3 Citations (Scopus)

3D-QSAR based pharmacophore modeling and virtual screening for identification of novel G protein-coupled receptor40 agonists

Lu, P., Wang, Y., Ouyang, P. K., She, J-X. & He, M., Jul 1 2015, In : Current Computer-Aided Drug Design. 11, 1, p. 51-56 6 p.

Research output: Contribution to journalArticle

Quantitative Structure-Activity Relationship
GTP-Binding Proteins
Random Allocation
Hydrogen
Databases