• 434 Citations
  • 8 h-Index
20132018
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Fingerprint Dive into the research topics where Joanna Ruth Appel is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 4 Similar Profiles
Protein Transport Medicine & Life Sciences
Neuronal Plasticity Medicine & Life Sciences
Neurogenesis Medicine & Life Sciences
Microglia Medicine & Life Sciences
Obesity Medicine & Life Sciences
Synucleins Medicine & Life Sciences
Dopaminergic Neurons Medicine & Life Sciences
Endosomes Medicine & Life Sciences

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Research Output 2013 2018

  • 434 Citations
  • 8 h-Index
  • 8 Article
  • 1 Review article
7 Citations (Scopus)

Increased microglial activity, impaired adult hippocampal neurogenesis, and depressive-like behavior in microglial VPS35-depleted mice

Appel, J. R., Ye, S., Tang, F., Sun, D., Zhang, H., Mei, L. & Xiong, W. C., Jun 27 2018, In : Journal of Neuroscience. 38, 26, p. 5949-5968 20 p.

Research output: Contribution to journalArticle

Neurogenesis
Microglia
Dentate Gyrus
Dendritic Spines
Alzheimer Disease
84 Citations (Scopus)

VPS35 Deficiency or Mutation Causes Dopaminergic Neuronal Loss by Impairing Mitochondrial Fusion and Function

Tang, F., Liu, W., Hu, J. X., Appel, J. R., Ye, J., Mei, L. & Xiong, W., Sep 8 2015, In : Cell Reports. 12, 10, p. 1631-1643 13 p.

Research output: Contribution to journalArticle

Mitochondrial Dynamics
Protein Transport
Sorting
Fusion reactions
Dopaminergic Neurons
82 Citations (Scopus)
Synucleins
Lysosome-Associated Membrane Glycoproteins
Endosomes
Dopaminergic Neurons
Autophagy
37 Citations (Scopus)

Glucocorticoid receptor activation impairs hippocampal plasticity by suppressing BDNF expression in obese mice

Wosiski-Kuhn, M., Appel, J. R., Gomez-Sanchez, E. P., Gomez-Sanchez, C. E. & Stranahan, A. M., Jan 1 2014, In : Psychoneuroendocrinology. 42, p. 165-177 13 p.

Research output: Contribution to journalArticle

Obese Mice
Brain-Derived Neurotrophic Factor
Glucocorticoid Receptors
Glucocorticoids
Obesity
30 Citations (Scopus)

Glucocorticoid sensitization of microglia in a genetic mouse model of obesity and diabetes

Dey, A., Hao, S., Appel, J. R., Wosiski-Kuhn, M. & Stranahan, A. M., Jan 1 2014, In : Journal of Neuroimmunology. 269, 1-2, p. 20-27 8 p.

Research output: Contribution to journalArticle

Genetic Models
Microglia
Glucocorticoids
Obesity
Corticosterone