Joanna Ruth Appel


  • 380 Citations
  • 8 h-Index
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  • 3 Similar Profiles
Protein Transport Medicine & Life Sciences
Neuronal Plasticity Medicine & Life Sciences
Neurogenesis Medicine & Life Sciences
Microglia Medicine & Life Sciences
Obesity Medicine & Life Sciences
Dopaminergic Neurons Medicine & Life Sciences
Endosomes Medicine & Life Sciences
alpha-Synuclein Medicine & Life Sciences

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Research Output 2013 2018

  • 380 Citations
  • 8 h-Index
  • 8 Article
  • 1 Review article
3 Citations

Increased microglial activity, impaired adult hippocampal neurogenesis, and depressive-like behavior in microglial VPS35-depleted mice

Appel, J. R., Ye, S., Tang, F., Sun, D., Zhang, H., Mei, L. & Xiong, W. C., Jun 27 2018, In : Journal of Neuroscience. 38, 26, p. 5949-5968 20 p.

Research output: Contribution to journalArticle

Dentate Gyrus
Dendritic Spines
Alzheimer Disease
69 Citations

VPS35 Deficiency or Mutation Causes Dopaminergic Neuronal Loss by Impairing Mitochondrial Fusion and Function

Tang, F., Liu, W., Hu, J. X., Appel, J. R., Ye, J., Mei, L. & Xiong, W. C., Sep 8 2015, In : Cell Reports. 12, 10, p. 1631-1643 13 p.

Research output: Contribution to journalArticle

Mitochondrial Dynamics
Protein Transport
Fusion reactions
Dopaminergic Neurons
73 Citations
Lysosome-Associated Membrane Glycoproteins
Dopaminergic Neurons
33 Citations

Glucocorticoid receptor activation impairs hippocampal plasticity by suppressing BDNF expression in obese mice

Wosiski-Kuhn, M., Appel, J. R., Gomez-Sanchez, E. P., Gomez-Sanchez, C. E. & Stranahan, A. M., Jan 1 2014, In : Psychoneuroendocrinology. 42, p. 165-177 13 p.

Research output: Contribution to journalArticle

Obese Mice
Brain-Derived Neurotrophic Factor
Glucocorticoid Receptors
27 Citations

Glucocorticoid sensitization of microglia in a genetic mouse model of obesity and diabetes

Dey, A., Hao, S., Appel, J. R., Wosiski-Kuhn, M. & Stranahan, A. M., Jan 1 2014, In : Journal of Neuroimmunology. 269, 1-2, p. 20-27 8 p.

Research output: Contribution to journalArticle

Genetic Models