Joanna Ruth Appel

Instructor

  • 356 Citations
  • 8 h-Index
20132018
If you made any changes in Pure, your changes will be visible here soon.

Fingerprint Fingerprint is based on mining the text of the experts' scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 4 Similar Profiles
Protein Transport Medicine & Life Sciences
Neuronal Plasticity Medicine & Life Sciences
Neurogenesis Medicine & Life Sciences
Microglia Medicine & Life Sciences
Obesity Medicine & Life Sciences
Dopaminergic Neurons Medicine & Life Sciences
Endosomes Medicine & Life Sciences
alpha-Synuclein Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 2013 2018

  • 356 Citations
  • 8 h-Index
  • 8 Article
  • 1 Review article
2 Citations

Increased microglial activity, impaired adult hippocampal neurogenesis, and depressive-like behavior in microglial VPS35-depleted mice

Appel, J. R., Ye, S., Tang, F., Sun, D., Zhang, H., Mei, L. & Xiong, W. C., Jun 27 2018, In : Journal of Neuroscience. 38, 26, p. 5949-5968 20 p.

Research output: Contribution to journalArticle

Neurogenesis
Microglia
Dentate Gyrus
Dendritic Spines
Alzheimer Disease
66 Citations

VPS35 Deficiency or Mutation Causes Dopaminergic Neuronal Loss by Impairing Mitochondrial Fusion and Function

Tang, F. L., Liu, W., Hu, J. X., Erion, J. R., Ye, J., Mei, L. & Xiong, W. C., Sep 8 2015, In : Cell Reports. 12, 10, p. 1631-1643 13 p.

Research output: Contribution to journalArticle

Mitochondrial Dynamics
Protein Transport
Sorting
Fusion reactions
Dopaminergic Neurons
70 Citations

VPS35 in dopamine neurons is required for endosome-to- golgi retrieval of Lamp2a, a receptor of chaperone- mediated autophagy that is critical for α-synuclein degradation and prevention of pathogenesis of Parkinson’s disease

Tang, F. L., Erion, J. R., Tian, Y., Liu, W., Yin, D. M., Ye, J., Tang, B., Mei, L. & Xiong, W. C., Jul 22 2015, In : Journal of Neuroscience. 35, 29, p. 10613-10628 16 p.

Research output: Contribution to journalArticle

Lysosome-Associated Membrane Glycoproteins
alpha-Synuclein
Endosomes
Dopaminergic Neurons
Autophagy
29 Citations

Glucocorticoid receptor activation impairs hippocampal plasticity by suppressing BDNF expression in obese mice

Wosiski-Kuhn, M., Erion, J. R., Gomez-Sanchez, E. P., Gomez-Sanchez, C. E. & Stranahan, A. M., Jan 1 2014, In : Psychoneuroendocrinology. 42, p. 165-177 13 p.

Research output: Contribution to journalArticle

Obese Mice
Brain-Derived Neurotrophic Factor
Glucocorticoid Receptors
Glucocorticoids
Obesity
27 Citations

Glucocorticoid sensitization of microglia in a genetic mouse model of obesity and diabetes

Dey, A., Hao, S., Erion, J. R., Wosiski-Kuhn, M. & Stranahan, A. M., Jan 1 2014, In : Journal of Neuroimmunology. 269, 1-2, p. 20-27 8 p.

Research output: Contribution to journalArticle

Genetic Models
Microglia
Glucocorticoids
Obesity
Corticosterone