Lei Wang

Research Scientist

  • 1814 Citations
  • 16 h-Index
19962017
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Research Output 1996 2017

  • 1814 Citations
  • 16 h-Index
  • 22 Article
  • 2 Review article
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Article
13 Citations (Scopus)
Minocycline
Stroke
Cerebrovascular Circulation
Tissue Plasminogen Activator
Therapeutics
14 Citations (Scopus)

Activation of myeloid TLR4 Mediates T lymphocyte polarization after traumatic brain injury

Braun, M., Vaibhav, K., Saad, N., Fatima, S., Brann, D. W., Vender, J. R., Wang, L., Hoda, MD. N., Baban, B. & Dhandapani, K. M., May 1 2017, In : Journal of Immunology. 198, 9, p. 3615-3626 12 p.

Research output: Contribution to journalArticle

T-Lymphocytes
Macrophages
Monocytes
Adaptive Immunity
Brain
11 Citations (Scopus)

Balanced dopamine is critical for pattern completion during associative memory recall

Li, F., Wang, L., Shen, X. & Tsien, J. Z., Nov 17 2010, In : PloS one. 5, 10, e15401.

Research output: Contribution to journalArticle

dopamine
Dopamine
Data storage equipment
Cues
Dopamine Plasma Membrane Transport Proteins
33 Citations (Scopus)

CaMKII Activation State Underlies Synaptic Labile Phase of LTP and Short-Term Memory Formation

Wang, H., Feng, R., Wang, L., Li, F., Cao, X. & Tsien, J. Z., Oct 28 2008, In : Current Biology. 18, 20, p. 1546-1554 9 p.

Research output: Contribution to journalArticle

Calcium-Calmodulin-Dependent Protein Kinase Type 2
Short-Term Memory
Chemical activation
Data storage equipment
Learning
22 Citations (Scopus)

Conditional knockout of NMDA receptors in dopamine neurons prevents nicotine-conditioned place preference

Wang, L., Li, F., Shen, X. & Tsien, J. Z., Jan 7 2010, In : PloS one. 5, 1, e8616.

Research output: Contribution to journalArticle

nicotine
Dopaminergic Neurons
N-Methyl-D-Aspartate Receptors
Nicotine
Neurons
995 Citations (Scopus)

Control of memory formation through regulated expression of a CaMKII transgene

Mayford, M., Bach, M. E., Huang, Y. Y., Wang, L., Hawkins, R. D. & Kandel, E. R., Dec 6 1996, In : Science. 274, 5293, p. 1678-1683 6 p.

Research output: Contribution to journalArticle

Calcium-Calmodulin-Dependent Protein Kinases
Transgenes
Prosencephalon
Calcium
Critical Pathways
31 Citations (Scopus)

Dietary supplementation with uridine-5′-monophosphate (UMP), a membrane phosphatide precursor, increases acetylcholine level and release in striatum of aged rat

Wang, L., Albrecht, M. A. & Wurtman, R. J., Jan 16 2007, In : Brain Research. 1133, 1, p. 42-48 7 p.

Research output: Contribution to journalArticle

Uridine Monophosphate
Dietary Supplements
Acetylcholine
Phospholipids
Membranes
39 Citations (Scopus)

Dietary uridine-5′-monophosphate supplementation increases potassium-evoked dopamine release and promotes neurite outgrowth in aged rats

Wang, L., Pooler, A. M., Albrecht, M. A. & Wurtman, R. J., Sep 1 2005, In : Journal of Molecular Neuroscience. 27, 1, p. 137-146 10 p.

Research output: Contribution to journalArticle

Uridine Monophosphate
Dopamine
Potassium
Cytidine Diphosphate Choline
Corpus Striatum
10 Citations (Scopus)

Dopamine rebound-excitation theory: Putting brakes on PTSD

Lee, J. C., Wang, L. & Tsien, J. Z., Sep 27 2016, In : Frontiers in Psychiatry. 7, SEP, 163.

Research output: Contribution to journalArticle

Dopaminergic Neurons
Post-Traumatic Stress Disorders
Dopamine
Fear
Anxiety
18 Citations (Scopus)

Efficient reproduction of cynomolgus monkey using pronuclear embryo transfer technique

Sun, Q., Dong, J., Yang, W., Jin, Y., Yang, M., Wang, Y., Wang, P. L., Hu, Y. & Tsien, J. Z., Sep 2 2008, In : Proceedings of the National Academy of Sciences of the United States of America. 105, 35, p. 12956-12960 5 p.

Research output: Contribution to journalArticle

Macaca fascicularis
Embryo Transfer
Reproduction
Embryonic Structures
Birth Rate
85 Citations (Scopus)

Genetic enhancement of memory and long-term potentiation but not CA1 long-term depression in NR2B transgenic rats

Wang, D., Cui, Z., Zeng, Q., Kuang, H., Wang, L. P., Tsien, J. Z. & Cao, X., Oct 19 2009, In : PloS one. 4, 10, e7486.

Research output: Contribution to journalArticle

Genetic Enhancement
Transgenic Rats
Long-Term Potentiation
Rats
genetically modified organisms
55 Citations (Scopus)

Inducible and Selective Erasure of Memories in the Mouse Brain via Chemical-Genetic Manipulation

Cao, X., Wang, H., Mei, B., An, S., Yin, L., Wang, L. & Tsien, J. Z., Oct 23 2008, In : Neuron. 60, 2, p. 353-366 14 p.

Research output: Contribution to journalArticle

Brain
Fear
Calcium-Calmodulin-Dependent Protein Kinase Type 2
Genetic Techniques
Access to Information
76 Citations (Scopus)

In vivo evidence for NMDA receptor-mediated excitotoxicity in a murine genetic model of huntington disease

Heng, M. Y., Detloff, P. J., Wang, P. L., Tsien, J. Z. & Albin, R. L., Mar 11 2009, In : Journal of Neuroscience. 29, 10, p. 3200-3205 6 p.

Research output: Contribution to journalArticle

Genetic Models
Huntington Disease
N-Methyl-D-Aspartate Receptors
Corpus Striatum
Nerve Degeneration
39 Citations (Scopus)

Neural population-level memory traces in the mouse hippocampus

Chen, G., Wang, L. & Tsien, J. Z., Dec 1 2009, In : PLoS One. 4, 12, e8256.

Research output: Contribution to journalArticle

hippocampus
Hippocampus
Shock
Data storage equipment
mice
6 Citations (Scopus)

Neuronal pannexin-1 channels are not molecular routes of water influx during spreading depolarization-induced dendritic beading

Sword, J., Croom, D., Wang, L., Thompson, R. J. & Kirov, S. A., May 1 2017, In : Journal of Cerebral Blood Flow and Metabolism. 37, 5, p. 1626-1633 8 p.

Research output: Contribution to journalArticle

Water
Aquaporins
Pyramidal Cells
Photons
Chlorides
77 Citations (Scopus)

NMDA receptors in dopaminergic neurons are crucial for habit learning

Wang, L., Li, F., Wang, D., Xie, K., Wang, D., Shen, X. & Tsien, J. Z., Dec 22 2011, In : Neuron. 72, 6, p. 1055-1066 12 p.

Research output: Contribution to journalArticle

Dopaminergic Neurons
N-Methyl-D-Aspartate Receptors
Habits
Learning
Dopamine
2 Citations (Scopus)

On brain activity mapping: Insights and lessons from Brain Decoding Project to map memory patterns in the hippocampus

Tsien, J. Z., Li, M., Osan, R., Chen, G. F., Lin, L. N., Wang, L., Frey, S. M., Frey, J. U., Zhu, D. J., Liu, T. M., Zhao, F. & Kuang, H., Jan 1 2013, In : Science China Life Sciences. 56, 9, p. 767-779 13 p.

Research output: Contribution to journalArticle

Brain Mapping
hippocampus
Decoding
brain
Hippocampus
37 Citations (Scopus)

Oral L-glutamine increases GABA levels in striatal tissue and extracellular fluid

Wang, L., Maher, T. J. & Wurtman, R. J., Apr 1 2007, In : FASEB Journal. 21, 4, p. 1227-1232 6 p.

Research output: Contribution to journalArticle

Aminobutyrates
Corpus Striatum
Extracellular Fluid
Glutamine
Tissue
41 Citations (Scopus)

Remote Ischemic Postconditioning: Harnessing Endogenous Protection in a Murine Model of Vascular Cognitive Impairment

Khan, M. B., Hoda, M. N., Vaibhav, K., Giri, S., Wang, P., Waller, J. L., Ergul, A., Dhandapani, K. M., Fagan, S. C. & Hess, D. C., Jan 1 2014, In : Translational Stroke Research. 6, 1, p. 69-77 9 p.

Research output: Contribution to journalArticle

Ischemic Postconditioning
Carotid Stenosis
Cerebrovascular Circulation
Blood Vessels
Cognition
49 Citations (Scopus)

Restorative effects of uridine plus docosahexaenoic acid in a rat model of Parkinson's disease

Cansev, M., Ulus, I. H., Wang, L., Maher, T. J. & Wurtman, R. J., Nov 1 2008, In : Neuroscience Research. 62, 3, p. 206-209 4 p.

Research output: Contribution to journalArticle

Docosahexaenoic Acids
Uridine
Uridine Monophosphate
Parkinson Disease
Oxidopamine
118 Citations (Scopus)

Synaptic proteins and phospholipids are increased in gerbil brain by administering uridine plus docosahexaenoic acid orally

Wurtman, R. J., Ulus, I. H., Cansev, M., Watkins, C. J., Wang, L. & Marzloff, G., May 9 2006, In : Brain Research. 1088, 1, p. 83-92 10 p.

Research output: Contribution to journalArticle

Gerbillinae
Docosahexaenoic Acids
Uridine
Phospholipids
Choline
22 Citations (Scopus)

The immunologic effect of TGF-beta1 chitosan nanoparticle plasmids on ovalbumin-induced allergic BALB/c mice

Li, F., Wang, L., Jin, X. M., Yan, C. H., Jiang, S. & Shen, X. M., Feb 1 2009, In : Immunobiology. 214, 2, p. 87-99 13 p.

Research output: Contribution to journalArticle

Transforming Growth Factor beta1
Ovalbumin
Chitosan
Transforming Growth Factor beta
Nanoparticles