Lesleyann Hawthorn

Professor

  • 1950 Citations
  • 26 h-Index
1978 …2020

Research output per year

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Research Output

  • 1950 Citations
  • 26 h-Index
  • 58 Article
  • 1 Comment/debate
  • 1 Review article
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Article
2020

Inactivation of Lgi1 in murine neuronal precursor cells leads to dysregulation of axon guidance pathways

Silva, J., Hawthorn, L. & Cowell, J. K., Mar 2020, In : Genomics. 112, 2, p. 1167-1172 6 p.

Research output: Contribution to journalArticle

2019

Distinct signaling programs associated with progression of FGFR1 driven leukemia in a mouse model of stem cell leukemia lymphoma syndrome

Silva, M. J., Chang, C. S., Hu, T., Qin, H., Kitamura, E., Hawthorn, L., Ren, M. & Cowell, J. K., Dec 2019, In : Genomics. 111, 6, p. 1566-1573 8 p.

Research output: Contribution to journalArticle

2 Scopus citations

Genomic analysis of racial differences in triple negative breast cancer

Chang, C. S., Kitamura, E., Johnson, J., Bollag, R. & Hawthorn, L., Dec 2019, In : Genomics. 111, 6, p. 1529-1542 14 p.

Research output: Contribution to journalArticle

4 Scopus citations
2018

MiR-339 promotes development of stem cell leukemia/lymphoma syndrome via downregulation of the BCL2L11 and BAX proapoptotic genes

Hu, T., Chong, Y., Lu, S., Wang, R., Qin, H., Silva, J., Kitamura, E., Chang, C. S., Hawthorn, L. A. & Cowell, J. K., Jul 1 2018, In : Cancer Research. 78, 13, p. 3522-3531 10 p.

Research output: Contribution to journalArticle

11 Scopus citations
2014

Evidence for field effect cancerization in colorectal cancer

Hawthorn, L., Lan, L. & Mojica, W., Feb 2014, In : Genomics. 103, 2-3, p. 211-221 11 p.

Research output: Contribution to journalArticle

27 Scopus citations

mRNA Transcript abundance during plant growth and the influence of Li+ exposure

Duff, M. C., Kuhne, W. W., Halverson, N. V., Chang, C. S., Kitamura, E., Hawthorn, L., Martinez, N. E., Stafford, C., Milliken, C. E., Caldwell, E. F. & Stieve-Caldwell, E., Dec 1 2014, In : Plant Science. 229, p. 262-279 18 p.

Research output: Contribution to journalArticle

4 Scopus citations

The niacin/butyrate receptor GPR109A suppresses mammary tumorigenesis by inhibiting cell survival

Elangovan, S., Pathania, R., Ramachandran, S., Ananth, S., Padia, R. N., Lan, L., Singh, N., Martin, P. M., Hawthorn, L., Prasad, P. D., Ganapathy, V. & Thangaraju, M., Feb 15 2014, In : Cancer Research. 74, 4, p. 1166-1178 13 p.

Research output: Contribution to journalArticle

53 Scopus citations
53 Scopus citations
2013

A systematic evaluation of miRNA: MRNA interactions involved in the migration and invasion of breast cancer cells

Luo, D., Wilson, J. M., Harvel, N., Liu, J., Pei, L., Huang, S., Hawthorn, L. & Shi, H., Mar 5 2013, In : Journal of Translational Medicine. 11, 1, 57.

Research output: Contribution to journalArticle

89 Scopus citations

Molecular mechanism of SLC5A8 inactivation in breast cancer

Elangovan, S., Pathania, R., Ramachandran, S., Ananth, S., Padia, R. N., Srinivas, S. R., Babu, E., Hawthorn, L., Schoenlein, P. V., Boettger, T., Smith, S. B., Prasad, P. D., Ganapathy, V. & Thangaraju, M., Nov 6 2013, In : Molecular and Cellular Biology. 33, 19, p. 3920-3935 16 p.

Research output: Contribution to journalArticle

20 Scopus citations
2011

Analysis of wilms tumors using SNP mapping array-based comparative genomic hybridization

Hawthorn, L. & Cowell, J. K., May 4 2011, In : PloS one. 6, 4, e18941.

Research output: Contribution to journalArticle

18 Scopus citations
2010

Copy number and gene expression alterations in radiation-induced papillary thyroid carcinoma from chernobyl pediatric patients

Stein, L., Rothschild, J., Luce, J., Cowell, J. K., Thomas, G., Bogdanova, T. I., Tronko, M. D. & Hawthorn, L., May 1 2010, In : Thyroid. 20, 5, p. 475-487 13 p.

Research output: Contribution to journalArticle

48 Scopus citations

Integration of transcript expression, copy number and LOH analysis of infiltrating ductal carcinoma of the breast

Hawthorn, L., Luce, J., Stein, L. & Rothschild, J., Aug 27 2010, In : BMC Cancer. 10, 460.

Research output: Contribution to journalArticle

36 Scopus citations
5 Scopus citations
19 Scopus citations

Reexpression of LGI1 in glioma cells results in dysregulation of genes implicated in the canonical axon guidance pathway

Kunapuli, P., Lo, K., Hawthorn, L. & Cowell, J. K., Feb 1 2010, In : Genomics. 95, 2, p. 93-100 8 p.

Research output: Contribution to journalArticle

18 Scopus citations
2008

Identification of genes involved in squamous cell carcinoma of the lung using synchronized data from DNA copy number and transcript expression profiling analysis

Lo, K. C., Stein, L. C., Panzarella, J. A., Cowell, J. K. & Hawthorn, L., Mar 1 2008, In : Lung Cancer. 59, 3, p. 315-331 17 p.

Research output: Contribution to journalArticle

20 Scopus citations

Transformation of MCF-10A cells by random mutagenesis with frameshift mutagen ICR191: A model for identifying candidate breast-tumor suppressors

Zientek-Targosz, H., Kunnev, D., Hawthorn, L., Venkov, M., Matsui, S. I., Cheney, R. T. & Ionov, Y., Jun 5 2008, In : Molecular cancer. 7, 51.

Research output: Contribution to journalArticle

19 Scopus citations

Universal reference RNA is not a representative normal sample for oligonucleotide microarray studies

Mojica, W. D., Stein, L. & Hawthorn, L., Sep 1 2008, In : Pathology and Oncology Research. 14, 3, p. 243-251 9 p.

Research output: Contribution to journalArticle

4 Scopus citations
2007
8 Scopus citations

Candidate glioblastoma development gene identification using concordance between copy number abnormalities and gene expression level changes

Lo, K. C., Rossi, M. R., LaDuca, J., Hicks, D. G., Turpaz, Y., Hawthorn, L. & Cowell, J. K., Oct 1 2007, In : Genes Chromosomes and Cancer. 46, 10, p. 875-894 20 p.

Research output: Contribution to journalArticle

25 Scopus citations

Development of a murine model for blastoid variant mantle-cell lymphoma

Ford, R. J., Shen, L., Lin-Lee, Y. C., Pham, L. V., Multani, A., Zhou, H. J., Tamayo, A. T., Zhang, C. J., Hawthorn, L., Cowell, J. K. & Ambrus, J. L., Jun 1 2007, In : Blood. 109, 11, p. 4899-4906 8 p.

Research output: Contribution to journalArticle

25 Scopus citations

Identifying candidate colon cancer tumor suppressor genes using inhibition of nonsense-mediated mRNA decay in colon cancer cells

Ivanov, I., Lo, K. C., Hawthorn, L., Cowell, J. K. & Ionov, Y., May 3 2007, In : Oncogene. 26, 20, p. 2873-2884 12 p.

Research output: Contribution to journalArticle

66 Scopus citations

Platinum drug effects on the expression of genes in the polyamine pathway: Time-course and concentration-effect analysis based on Affymetrix gene expression profiling of A2780 ovarian carcinoma cells

Varma, R., Hector, S., Greco, W. R., Clark, K., Hawthorn, L., Porter, C. & Pendyala, L., Jun 2007, In : Cancer Chemotherapy and Pharmacology. 59, 6, p. 711-723 13 p.

Research output: Contribution to journalArticle

17 Scopus citations
2006

Characterization of cell-type specific profiles in tissues and isolated cells from squamous cell carcinomas of the lung

Hawthorn, L., Stein, L., Panzarella, J., Loewen, G. M. & Baumann, H., Aug 1 2006, In : Lung Cancer. 53, 2, p. 129-142 14 p.

Research output: Contribution to journalArticle

36 Scopus citations

Induction of the plasminogen activator inhibitor-2 in cells expressing the ZNF198/FGFR1 fusion kinase that is involved in atypical myeloproliferative disease

Kasyapa, C. S., Kunapuli, P., Hawthorn, L. & Cowell, J. K., May 1 2006, In : Blood. 107, 9, p. 3693-3699 7 p.

Research output: Contribution to journalArticle

21 Scopus citations
2005

Aberrant expression of novel and previously described cell membrane markers in human breast cancer cell lines and tumors

Huang, H., Groth, J., Sossey-Alaoui, K., Hawthorn, L., Beall, S. & Geradts, J., Jun 15 2005, In : Clinical Cancer Research. 11, 12, p. 4357-4364 8 p.

Research output: Contribution to journalArticle

57 Scopus citations

Gene expression profiling of a clonal isolate of oxaliplatin resistant ovarian carcinoma cell line A2780/C10

Varma, R. R., Hector, S. M., Clark, K., Greco, W. R., Hawthorn, L. & Pendyala, L., Oct 2005, In : Oncology Reports. 14, 4, p. 925-932 8 p.

Research output: Contribution to journalArticle

54 Scopus citations
24 Scopus citations

Microarray data mining for potential selenium targets in chemoprevention of prostate cancer

Zhang, H., Dong, Y., Zhao, H., Brooks, J. D., Hawthorn, L., Nowak, N., Marshall, J. R., Gao, A. C. & Ip, C., Jan 1 2005, In : Cancer Genomics and Proteomics. 2, 2, p. 97-113 17 p.

Research output: Contribution to journalArticle

32 Scopus citations

Novel amplicons on the short arm of chromosome 7 identified using high resolution array CGH contain over expressed genes in addition to EGFR in glioblastoma multiforme

Rossi, M. R., Duca, J. L., Matsui, S. I., Nowak, N. J., Hawthorn, L. & Cowell, J. K., Dec 1 2005, In : Genes Chromosomes and Cancer. 44, 4, p. 392-404 13 p.

Research output: Contribution to journalArticle

37 Scopus citations
63 Scopus citations
2004
82 Scopus citations

TIMP1 and SERPIN-A overexpression and TFF3 and CRABP1 underexpression as biomarkers for papillary thyroid carcinoma

Hawthorn, L., Stein, L., Varma, R., Wiseman, S., Loree, T. & Tan, D. F., Dec 1 2004, In : Head and Neck. 26, 12, p. 1069-1083 15 p.

Research output: Contribution to journalArticle

46 Scopus citations
2003

Delineation of the molecular basis for selenium-induced growth arrest in human prostate cancer cells by oligonucleotide array

Dong, Y., Zhang, H., Hawthorn, L., Ganther, H. E. & Ip, C., Jan 1 2003, In : Cancer Research. 63, 1, p. 52-59 8 p.

Research output: Contribution to journalArticle

176 Scopus citations
2000

A transcription map of the minimally deleted region from 13q14 in B-cell chronic lymphocytic leukemia as defined by large scale sequencing of the 650 kb critical region

Kitamura, E., Su, G., Sossey-Alaoui, K., Malaj, E., Lewis, J., Pan, H. Q., Hawthorn, L., Roe, B. & Cowell, J. K., Nov 23 2000, In : Oncogene. 19, 50, p. 5772-5780 9 p.

Research output: Contribution to journalArticle

13 Scopus citations

Decreased SLIM1 expression and increased gelsolin expression in failing human hearts measured by high-density oligonucleotide arrays

Yang, J., Moravec, C. S., Sussman, M. A., DiPaola, N. R., Fu, D., Hawthorn, L., Mitchell, C. A., Young, J. B., Francis, G. S., McCarthy, P. M. & Bond, M., Dec 19 2000, In : Circulation. 102, 25, p. 3046-3052 7 p.

Research output: Contribution to journalArticle

189 Scopus citations
1998
2 Scopus citations
1996

Incorporation of 35 novel gene transcripts into the physical and genetic map of human chromosome 13

Still, I. H., Roberts, T., Bia, B., Hawthorn, L., Auffray, C. & Cowell, J., Apr 15 1996, In : Genomics. 33, 2, p. 159-166 8 p.

Research output: Contribution to journalArticle

6 Scopus citations

Regional assignment of EST sequences on human chromosome 13

Hawthorn, L. & Cowell, J. K., Jan 1 1996, In : Cytogenetic and Genome Research. 72, 1, p. 72-77 6 p.

Research output: Contribution to journalArticle

10 Scopus citations
1995
20 Scopus citations

Integration of the physical and genetic linkage map for human chromosome 13

Hawthorn, L. & Cowell, J. K., Jun 10 1995, In : Genomics. 27, 3, p. 399-404 6 p.

Research output: Contribution to journalArticle

16 Scopus citations

Regional localisation of tri- and tetranucleotide repeat sequence-containing cosmids on chromosome 13

Hawthorn, L., Kapanadse, B., Yankovsky, N. & Cowell, J. K., Jan 1 1995, In : Cytogenetic and Genome Research. 70, 1-2, p. 102-103 2 p.

Research output: Contribution to journalArticle

3 Scopus citations
1994

A deletion hybrid breakpoint map of the chromosomal region 13q14-q21 orders 19 genetic markers in 10 intervals

Kooy, R. F., Verlind, E., Houwen, R. H. J., Shapiro, D. N., Hawthorn, L. A., Cowell, J. K., Scheffer, H. & Buys, C. H. C. M., Jan 1 1994, In : European Journal of Human Genetics. 2, 1, p. 59-65 7 p.

Research output: Contribution to journalArticle

12 Scopus citations

Assignment of 55 novel cosmids to seven subregions of chromosome 13 using fluorescence in situ hybridization

Hawthorn, L., Nizetic, D., Lehrach, H. & Cowell, J. K., May 1 1994, In : Genomics. 21, 1, p. 248-250 3 p.

Research output: Contribution to journalArticle

7 Scopus citations

Frequent homozygous deletions of the D13S25 locus in chromosome region 13q14 defines the location of a gene critical in leukaemogenesis in chronic B-cell lymphocytic leukaemia

Chapman, R. M., Corcoran, M. M., Gardiner, A., Hawthorn, L. A., Cowell, J. K. & Oscier, D. G., Apr 1 1994, In : Oncogene. 9, 4, p. 1289-1293 5 p.

Research output: Contribution to journalArticle

63 Scopus citations
1993
83 Scopus citations
1991

Ability of uropathogens to bind to tamm horsfall protein-coated renal tubular cells

Hawthorn, L., Bruce, A. W. & Reid, G., Sep 1 1991, In : Urological Research. 19, 5, p. 301-304 4 p.

Research output: Contribution to journalArticle

21 Scopus citations

Effect of bacterial, urine and substratum surface tension properties on bacterial adhesion to biomaterials

Reid, G., Beg, H. S., Preston, C. A. K. & Hawthorn, L., Aug 1 1991, In : Biofouling. 4, 1-3, p. 171-176 6 p.

Research output: Contribution to journalArticle

26 Scopus citations
1990

Exclusion of uropathogen adhesion to polymer surfaces by Lactobacillus acidophilus

Hawthorn, L. A. & Reid, G., Jan 1990, In : Journal of Biomedical Materials Research. 24, 1, p. 39-46 8 p.

Research output: Contribution to journalArticle

37 Scopus citations