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Madhav D Sharma

Principal Research Scientist

  • 4426 Citations
  • 16 h-Index
1986 …2018
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Research Output 1986 2018

  • 4426 Citations
  • 16 h-Index
  • 21 Article
  • 2 Review article
  • 1 Comment/debate
11 Citations (Scopus)

Activation of p53 in Immature Myeloid Precursor Cells Controls Differentiation into Ly6c+CD103+ Monocytic Antigen-Presenting Cells in Tumors

Sharma, M. D., Rodriguez, P. C., Koehn, B. H., Baban, B., Cui, Y., Guo, G., Shimoda, M., Pacholczyk, R. W., Shi, H., Lee, E. J., Xu, H., Johnson, T. S., He, Y., Mergoub, T., Venable, C., Bronte, V., Wolchok, J. D., Blazar, B. R. & Munn, D. H., Jan 16 2018, In : Immunity. 48, 1, p. 91-106.e6

Research output: Contribution to journal › Article

Antigen-Presenting Cells
Myeloid Cells
Immunotherapy
Cell Differentiation
Cross-Priming
2 Citations (Scopus)

Treg Destabilization and reprogramming: Implications for cancer immunotherapy

Munn, D. H., Sharma, M. D. & Johnson, T. S., Sep 15 2018, In : Cancer Research. 78, 18, p. 5191-5199 9 p.

Research output: Contribution to journal › Review article

Immunotherapy
Neoplasms
PTEN Phosphohydrolase
Cross-Priming
Indoleamine-Pyrrole 2,3,-Dioxygenase
11 Citations (Scopus)

IDO, PTEN-expressing Tregs and control of antigen-presentation in the murine tumor microenvironment

Munn, D. H., Sharma, M. D., Johnson, T. S. & Rodriguez, P., Aug 1 2017, In : Cancer Immunology, Immunotherapy. 66, 8, p. 1049-1058 10 p.

Research output: Contribution to journal › Review article

Indoleamine-Pyrrole 2,3,-Dioxygenase
Tumor Microenvironment
Antigen Presentation
Immunosuppressive Agents
Cytotoxins

The PTEN pathway in Tregs functions as a critical driver of the immunosuppressive tumor microenvironment and tolerance to apoptotic cells

Sharma, M. D., Shinde, R., McGaha, T. L., Huang, L., Holmgaard, R., Wolchok, J., Mautino, M., Celis, E., Sharpe, A., Francisco, L., Powell, J., Yagita, H., Mellor, A. L., Blazar, B. & Munn, D. H., Jan 1 2015, In : Journal for ImmunoTherapy of Cancer. 3, O19.

Research output: Contribution to journal › Article

Tumor Microenvironment
Immunosuppressive Agents
50 Citations (Scopus)

The PTEN pathway in Tregs is a critical driver of the suppressive tumor microenvironment

Sharma, M. D., Nov 6 2015, In : Science advances. 1, 10

Research output: Contribution to journal › Article

Open Access