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Madhav D Sharma

Principal Research Scientist

  • 4353 Citations
  • 16 h-Index
1986 …2018
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Regulatory T-Lymphocytes Medicine & Life Sciences
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Tumor Microenvironment Medicine & Life Sciences

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Research Output 1986 2018

  • 4353 Citations
  • 16 h-Index
  • 22 Article
  • 1 Comment/debate
  • 1 Review article
8 Citations

Activation of p53 in Immature Myeloid Precursor Cells Controls Differentiation into Ly6c+CD103+ Monocytic Antigen-Presenting Cells in Tumors

Sharma, M. D., Rodriguez, P. C., Koehn, B. H., Baban, B., Cui, Y., Guo, G., Shimoda, M., Pacholczyk, R. W., Shi, H., Lee, E. J., Xu, H., Johnson, T. S., He, Y., Mergoub, T., Venable, C., Bronte, V., Wolchok, J. D., Blazar, B. R. & Munn, D. H., Jan 16 2018, In : Immunity. 48, 1, p. 91-106.e6

Research output: Contribution to journal › Article

Antigen-Presenting Cells
Myeloid Cells
Immunotherapy
Cell Differentiation
Cross-Priming
1 Citations

Treg Destabilization and reprogramming: Implications for cancer immunotherapy

Munn, D. H., Sharma, M. D. & Johnson, T. S., Sep 15 2018, In : Cancer Research. 78, 18, p. 5191-5199 9 p.

Research output: Contribution to journal › Review article

Immunotherapy
Neoplasms
PTEN Phosphohydrolase
Cross-Priming
Indoleamine-Pyrrole 2,3,-Dioxygenase
9 Citations

IDO, PTEN-expressing Tregs and control of antigen-presentation in the murine tumor microenvironment

Munn, D. H., Sharma, M. D., Johnson, T. S. & Rodriguez, P., May 9 2017, (Accepted/In press) In : Cancer Immunology, Immunotherapy. p. 1-10 10 p.

Research output: Contribution to journal › Article

Indoleamine-Pyrrole 2,3,-Dioxygenase
Tumor Microenvironment
Antigen Presentation
Immunosuppressive Agents
Cytotoxins

The PTEN pathway in Tregs functions as a critical driver of the immunosuppressive tumor microenvironment and tolerance to apoptotic cells

Sharma, M. D., Shinde, R., McGaha, T., Huang, L., Holmgaard, R., Wolchok, J., Mautino, M., Celis, E., Sharpe, A., Francisco, L., Powell, J., Yagita, H., Mellor, A., Blazar, B. & Munn, D. H., Jan 1 2015, In : Journal for ImmunoTherapy of Cancer. 3, O19.

Research output: Contribution to journal › Article

Tumor Microenvironment
Immunosuppressive Agents
47 Citations

The PTEN pathway in Tregs is a critical driver of the suppressive tumor microenvironment

Sharma, M. D., Nov 6 2015, In : Science advances. 1, 10

Research output: Contribution to journal › Article

Open Access