• 1664 Citations
  • 25 h-Index
20052020

Research output per year

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Research Output

2005

Cross-sectional and whole bone structural properties of bear femurs are not compromised by annual periods of disuse

McGee, M. E., Black, H. L., Auger, J. & Donahue, S. W., Dec 1 2005, Proceedings of the 2005 Summer Bioengineering Conference, 2005 SBC. p. 1298-1299 2 p. (Proceedings of the 2005 Summer Bioengineering Conference; vol. 2005).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2006

Hibernating bears as a model for preventing disuse osteoporosis

Donahue, S. W., McGee, M. E., Harvey, K. B., Vaughan, M. R. & Robbins, C. T., Aug 28 2006, In : Journal of Biomechanics. 39, 8, p. 1480-1488 9 p.

Research output: Contribution to journalArticle

32 Scopus citations

Parathyroid hormone may maintain bone formation in hibernating black bears (Ursus americanus) to prevent disuse osteoporosis

Donahue, S. W., Galley, S. A., Vaughan, M. R., Patterson-Buckendahl, P., Demers, L. M., Vance, J. L. & McGee, M. E., May 1 2006, In : Journal of Experimental Biology. 209, 9, p. 1630-1638 9 p.

Research output: Contribution to journalArticle

60 Scopus citations
2007

Black bear femoral geometry and cortical porosity are not adversely affected by ageing despite annual periods of disuse (hibernation)

McGee, M. E., Miller, D. L., Auger, J., Black, H. L. & Donahue, S. W., Feb 1 2007, In : Journal of Anatomy. 210, 2, p. 160-169 10 p.

Research output: Contribution to journalArticle

11 Scopus citations

Black bear femoral porosity decreases and mechanical properties increase with age despite annual periods of disuse (hibernation)

McGee, M. E., Magic, K. W., Miller, D. L., Maki, A. J. & Donahue, S. W., Aug 1 2007, In : Engineering Fracture Mechanics. 74, 12, p. 1942-1952 11 p.

Research output: Contribution to journalArticle

9 Scopus citations
2008

Decreased bone turnover with balanced resorption and formation prevent cortical bone loss during disuse (hibernation) in grizzly bears (Ursus arctos horribilis)

McGee Lawrence, M. E., Maki, A. J., Johnson, S. E., Nelson, O. L., Robbins, C. T. & Donahue, S. W., Feb 1 2008, In : Bone. 42, 2, p. 396-404 9 p.

Research output: Contribution to journalArticle

41 Scopus citations
30 Scopus citations
2009

Grizzly bears (Ursus arctos horribilis) and black bears (Ursus americanus) prevent trabecular bone loss during disuse (hibernation)

McGee-Lawrence, M. E., Wojda, S. J., Barlow, L. N., Castillo, A. B., Kennedy, O., Auger, J., Black, H. L., Nelson, O. L., Robbins, C. T. & Donahue, S. W., Dec 1 2009, Proceedings of the ASME Summer Bioengineering Conference 2009, SBC2009. PART B ed. p. 959-960 2 p. (Proceedings of the ASME Summer Bioengineering Conference 2009, SBC2009; no. PART B).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Grizzly bears (Ursus arctos horribilis) and black bears (Ursus americanus) prevent trabecular bone loss during disuse (hibernation)

McGee-Lawrence, M. E., Wojda, S. J., Barlow, L. N., Drummer, T. D., Castillo, A. B., Kennedy, O., Condon, K. W., Auger, J., Black, H. L., Nelson, O. L., Robbins, C. T. & Donahue, S. W., Dec 1 2009, In : Bone. 45, 6, p. 1186-1191 6 p.

Research output: Contribution to journalArticle

40 Scopus citations

Six months of disuse during hibernation does not increase intracortical porosity or decrease cortical bone geometry, strength, or mineralization in black bear (Ursus americanus) femurs

McGee-Lawrence, M. E., Wojda, S. J., Barlow, L. N., Drummer, T. D., Bunnell, K., Auger, J., Black, H. L. & Donahue, S. W., Jul 22 2009, In : Journal of Biomechanics. 42, 10, p. 1378-1383 6 p.

Research output: Contribution to journalArticle

34 Scopus citations
2010

Effects of calcium-loading on egg production in ring-necked pheasants

Jones, L. R., Black, H. L., White, C. M., Paul Johnston, N., McGee, M. E., Donahue, S. W. & Eggett, D. L., Aug 1 2010, In : Journal of Wildlife Management. 74, 6, p. 1295-1300 6 p.

Research output: Contribution to journalArticle

3 Scopus citations

Histone deacetylase 3 depletion in osteo/chondroprogenitor cells decreases bone density and increases marrow fat

Razidlo, D. F., Whitney, T. J., Casper, M. E., McGee-Lawrence, M. E., Stensgard, B. A., Li, X., Secreto, F. J., Knutson, S. K., Hiebert, S. W. & Westendorf, J. J., 2010, In : PloS one. 5, 7, e11492.

Research output: Contribution to journalArticle

74 Scopus citations

The Ewing's sarcoma fusion protein, EWS-FLI, binds Runx2 and blocks osteoblast differentiation

Li, X., McGee Lawrence, M. E., Decker, M. & Westendorf, J. J., Nov 1 2010, In : Journal of cellular biochemistry. 111, 4, p. 933-943 11 p.

Research output: Contribution to journalArticle

23 Scopus citations

The histone deacetylase inhibitor, vorinostat, reduces tumor growth at the metastatic bone site and associated osteolysis, but promotes normal bone loss

Pratap, J., Akech, J., Wixted, J. J., Szabo, G., Hussain, S., McGee Lawrence, M. E., Li, X., Bedard, K., Dhillon, R. J., Van Wijnen, A. J., Stein, J. L., Stein, G. S., Westendorf, J. J. & Lian, J. B., Dec 1 2010, In : Molecular cancer therapeutics. 9, 12, p. 3210-3220 11 p.

Research output: Contribution to journalArticle

32 Scopus citations
2011

Hdac-mediated control of endochondral and intramembranous ossification

Bradley, E. W., McGee-Lawrence, M. E. & Westendorf, J. J., Jan 1 2011, In : Critical Reviews in Eukaryotic Gene Expression. 21, 2, p. 101-113 13 p.

Research output: Contribution to journalReview article

39 Scopus citations

Histone deacetylases in skeletal development and bone mass maintenance

McGee-Lawrence, M. E. & Westendorf, J. J., Mar 15 2011, In : Gene. 474, 1-2, p. 1-11 11 p.

Research output: Contribution to journalReview article

70 Scopus citations

Suberoylanilide hydroxamic acid (SAHA; vorinostat) causes bone loss by inhibiting immature osteoblasts

McGee Lawrence, M. E., McCleary-Wheeler, A. L., Secreto, F. J., Razidlo, D. F., Zhang, M., Stensgard, B. A., Li, X., Stein, G. S., Lian, J. B. & Westendorf, J. J., May 1 2011, In : Bone. 48, 5, p. 1117-1126 10 p.

Research output: Contribution to journalArticle

51 Scopus citations

Thirteen-lined ground squirrels (Ictidomys tridecemlineatus) show microstructural bone loss during hibernation but preserve bone macrostructural geometry and strength

McGee-Lawrence, M. E., Stoll, D. M., Mantila, E. R., Fahrner, B. K., Carey, H. V. & Donahue, S. W., Apr 2011, In : Journal of Experimental Biology. 214, 8, p. 1240-1247 8 p.

Research output: Contribution to journalArticle

25 Scopus citations
2012

Black bear parathyroid hormone has greater anabolic effects on trabecular bone in dystrophin-deficient mice than in wild type mice

Gray, S. K., McGee-Lawrence, M. E., Sanders, J. L., Condon, K. W., Tsai, C. J. & Donahue, S. W., Sep 1 2012, In : Bone. 51, 3, p. 578-585 8 p.

Research output: Contribution to journalArticle

12 Scopus citations

Update on Wnt signaling in bone cell biology and bone disease

Monroe, D. G., McGee-Lawrence, M. E., Oursler, M. J. & Westendorf, J. J., Jan 15 2012, In : Gene. 492, 1, p. 1-18 18 p.

Research output: Contribution to journalReview article

268 Scopus citations

Yellow-bellied Marmots (Marmota flaviventris) preserve bone strength and microstructure during hibernation

Wojda, S. J., McGee-Lawrence, M. E., Gridley, R. A., Auger, J., Black, H. L. & Donahue, S. W., Jan 1 2012, In : Bone. 50, 1, p. 182-188 7 p.

Research output: Contribution to journalArticle

16 Scopus citations
2013

Animal Models of Bone Disease-B

McGee-Lawrence, M. E., Secreto, F. J. & Syed, F. A., Jul 2013, Animal Models for the Study of Human Disease. Elsevier Inc., p. 391-417 27 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Black bears with longer disuse (hibernation) periods have lower femoral osteon population density and greater mineralization and intracortical porosity

Wojda, S. J., Weyland, D. R., Gray, S. K., Mcgee-Lawrence, M. E., Drummer, T. D. & Donahue, S. W., Aug 1 2013, In : Anatomical Record. 296, 8, p. 1148-1153 6 p.

Research output: Contribution to journalArticle

8 Scopus citations

Corrigendum to "Histone deacetylase 3 is required for maintenance of bone mass during aging" [Bone 52 (2013) 296-307]

McGee Lawrence, M. E., Bradley, E. W., Dudakovic, A., Carlson, S. W., Ryan, Z. C., Kumar, R., Dadsetan, M., Yaszemski, M. J., Chen, Q., An, K. N. & Westendorf, J. J., Mar 1 2013, In : Bone. 53, 1, 1 p.

Research output: Contribution to journalComment/debate

Histone deacetylase 3 is required for maintenance of bone mass during aging

McGee Lawrence, M. E., Bradley, E. W., Dudakovic, A., Carlson, S. W., Ryan, Z. C., Kumar, R., Dadsetan, M., Yaszemski, M. J., Chen, Q., An, K. N. & Westendorf, J. J., Jan 1 2013, In : Bone. 52, 1, p. 296-307 12 p.

Research output: Contribution to journalArticle

50 Scopus citations

Histone deacetylase inhibition promotes osteoblast maturation by altering the histone H4 epigenome and reduces akt phosphorylation

Dudakovic, A., Evans, J. M., Li, Y., Middha, S., McGee Lawrence, M. E., Van Wijnen, A. J. & Westendorf, J. J., Oct 4 2013, In : Journal of Biological Chemistry. 288, 40, p. 28783-28791 9 p.

Research output: Contribution to journalArticle

48 Scopus citations

Reply to vorinostat induced bone loss in mice

Westendorf, J. J. & McGee-Lawrence, M. E., Dec 1 2013, In : Bone. 57, 2, p. 531-532 2 p.

Research output: Contribution to journalLetter

1 Scopus citations

Runx2 protein represses axin2 expression in osteoblasts and is required for craniosynostosis in axin2-deficient mice

McGee Lawrence, M. E., Li, X., Bledsoe, K. L., Wu, H., Hawse, J. R., Subramaniam, M., Razidlo, D. F., Stensgard, B. A., Stein, G. S., Van Wijnen, A. J., Lian, J. B., Hsu, W. & Westendorf, J. J., Feb 22 2013, In : Journal of Biological Chemistry. 288, 8, p. 5291-5302 12 p.

Research output: Contribution to journalArticle

25 Scopus citations

Sclerostin alters serum vitamin D metabolite and fibroblast growth factor 23 concentrations and the urinary excretion of calcium

Ryan, Z. C., Ketha, H., McNulty, M. S., McGee-Lawrence, M., Craig, T. A., Grande, J. P., Westendorf, J. J., Singh, R. J. & Kumar, R., Apr 9 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 15, p. 6199-6204 6 p.

Research output: Contribution to journalArticle

72 Scopus citations

Sclerostin deficient mice rapidly heal bone defects by activating β-catenin and increasing intramembranous ossification

McGee-Lawrence, M. E., Ryan, Z. C., Carpio, L. R., Kakar, S., Westendorf, J. J. & Kumar, R., Nov 29 2013, In : Biochemical and Biophysical Research Communications. 441, 4, p. 886-890 5 p.

Research output: Contribution to journalArticle

32 Scopus citations
2014

Aberrant bone density in aging mice lacking the adenosine transporter ENT1

Hinton, D. J., McGee-Lawrence, M. E., Lee, M. R., Kwong, H. K., Westendorf, J. J. & Choi, D. S., Feb 19 2014, In : PloS one. 9, 2, e88818.

Research output: Contribution to journalArticle

14 Scopus citations

Enhanced prostacyclin formation and Wnt signaling in sclerostin deficient osteocytes and bone

Ryan, Z. C., Craig, T. A., Salisbury, J. L., Carpio, L. R., McGee-Lawrence, M., Westendorf, J. J. & Kumar, R., May 23 2014, In : Biochemical and Biophysical Research Communications. 448, 1, p. 83-88 6 p.

Research output: Contribution to journalArticle

5 Scopus citations

Induction of fully stabilized cortical bone defects to study intramembranous bone regeneration

McGee Lawrence, M. E. & Razidlo, D. F., Oct 20 2014, Osteoporosis and Osteoarthritis. Springer New York, p. 183-192 10 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

4 Scopus citations

Osteoblasts protect AML cells from SDF-1-induced apoptosis

Kremer, K. N., Dudakovic, A., McGee Lawrence, M. E., Philips, R. L., Hess, A. D., Smith, B. D., Van Wijnen, A. J., Karp, J. E., Kaufmann, S. H., Westendorf, J. J. & Hedin, K. E., Jun 2014, In : Journal of cellular biochemistry. 115, 6, p. 1128-1137 10 p.

Research output: Contribution to journalArticle

21 Scopus citations

Runx2 is required for early stages of endochondral bone formation but delays final stages of bone repair in Axin2-deficient mice

McGee Lawrence, M. E., Carpio, L. R., Bradley, E. W., Dudakovic, A., Lian, J. B., van Wijnen, A. J., Kakar, S., Hsu, W. & Westendorf, J. J., Sep 2014, In : Bone. 66, p. 277-286 10 p.

Research output: Contribution to journalArticle

26 Scopus citations

RUNX3 facilitates growth of Ewing sarcoma cells

Bledsoe, K. L., Mcgee-Lawrence, M. E., Camilleri, E. T., Wang, X., Riester, S. M., van Wijnen, A. J., Oliveira, A. M. & Westendorf, J. J., Dec 2014, In : Journal of Cellular Physiology. 229, 12, p. 2049-2056 8 p.

Research output: Contribution to journalArticle

8 Scopus citations
2015
7 Scopus citations

Caloric restriction and the adipokine leptin alter the SDF-1 signaling axis in bone marrow and in bone marrow derived mesenchymal stem cells

Periyasamy Thandavan, S., Herberg, S., Arounleut, P., Upadhyay, S., Dukes, A., Davis, C. M., Johnson, M. H., McGee Lawrence, M. E., Hamrick, M. W., Isales, C. M. & Hill, W. D., Jul 5 2015, In : Molecular and Cellular Endocrinology. 410, p. 64-72 9 p.

Research output: Contribution to journalReview article

7 Scopus citations

Conditional deletion of Hdac3 in osteoprogenitor cells attenuates diet-induced systemic metabolic dysfunction

McGee-Lawrence, M. E., White, T. A., LeBrasseur, N. K. & Westendorf, J. J., Jul 5 2015, In : Molecular and Cellular Endocrinology. 410, p. 42-51 10 p.

Research output: Contribution to journalReview article

9 Scopus citations

Epigenetic control of skeletal development by the histone methyltransferase Ezh2

Dudakovic, A., Camilleri, E. T., Xu, F., Riester, S. M., McGee Lawrence, M. E., Bradley, E. W., Paradise, C. R., Lewallen, E. A., Thaler, R., Deyle, D. R., Larson, A. N., Lewallen, D. G., Dietz, A. B., Stein, G. S., Montecino, M. A., Westendorf, J. J. & Van Wijnen, A. J., Nov 13 2015, In : Journal of Biological Chemistry. 290, 46, p. 27604-27617 14 p.

Research output: Contribution to journalArticle

68 Scopus citations

Histone deacetylase inhibition destabilizes the multi-potent state of uncommitted adipose-derived mesenchymal stromal cells

Dudakovic, A., Camilleri, E. T., Lewallen, E. A., McGee Lawrence, M. E., Riester, S. M., Kakar, S., Montecino, M., Stein, G. S., Ryoo, H. M., Dietz, A. B., Westendorf, J. J. & Van Wijnen, A. J., Jan 1 2015, In : Journal of Cellular Physiology. 230, 1, p. 52-62 11 p.

Research output: Contribution to journalArticle

34 Scopus citations

Histone deacetylases in bone development and skeletal disorders

Bradley, E. W., Carpio, L. R., Van Wijnen, A. J., McGee-Lawrence, M. E. & Westendorf, J. J., Sep 9 2015, In : Physiological reviews. 95, 4, p. 1359-1381 23 p.

Research output: Contribution to journalArticle

51 Scopus citations

Induction of fully stabilized cortical bone defects to study intramembranous bone regeneration

McGee Lawrence, M. E. & Razidlo, D. F., Jan 1 2015, In : Methods in Molecular Biology. 1226, p. 183-192 10 p.

Research output: Contribution to journalArticle

Suppressed bone remodeling in black bears conserves energy and bone mass during hibernation

McGee-Lawrence, M., Buckendahl, P., Carpenter, C., Henriksen, K., Vaughan, M. & Donahue, S., Jul 1 2015, In : Journal of Experimental Biology. 218, 13, p. 2067-2074 8 p.

Research output: Contribution to journalArticle

28 Scopus citations
2016

Arctic ground squirrels limit bone loss during the prolonged physical inactivity associated with hibernation

Wojda, S. J., Gridley, R. A., McGee Lawrence, M. E., Drummer, T. D., Hess, A., Kohl, F., Barnes, B. M. & Donahue, S. W., Jan 1 2016, In : Physiological and Biochemical Zoology. 89, 1, p. 72-80 9 p.

Research output: Contribution to journalArticle

8 Scopus citations

Deletion of Estrogen Receptor Beta in Osteoprogenitor Cells Increases Trabecular but Not Cortical Bone Mass in Female Mice

Nicks, K. M., Fujita, K., Fraser, D., McGregor, U., Drake, M. T., McGee-Lawrence, M. E., Westendorf, J. J., Monroe, D. G. & Khosla, S., Mar 1 2016, In : Journal of Bone and Mineral Research. 31, 3, p. 606-614 9 p.

Research output: Contribution to journalArticle

18 Scopus citations

Enhancer of zeste homolog 2 inhibition stimulates bone formation and mitigates bone loss caused by ovariectomy in skeletally mature mice

Dudakovic, A., Camilleri, E. T., Riester, S. M., Paradise, C. R., Gluscevic, M., O'Toole, T. M., Thaler, R., Evans, J. M., Yan, H., Subramaniam, M., Hawse, J. R., Stein, G. S., Montecino, M. A., McGee Lawrence, M. E., Westendorf, J. J. & Van Wijnen, A. J., Nov 18 2016, In : Journal of Biological Chemistry. 291, 47, p. 24594-24606 13 p.

Research output: Contribution to journalArticle

28 Scopus citations

Hdac3 Deficiency Increases Marrow Adiposity and Induces Lipid Storage and Glucocorticoid Metabolism in Osteochondroprogenitor Cells

McGee Lawrence, M. E., Carpio, L. R., Schulze, R. J., Pierce, J. L., McNiven, M. A., Farr, J. N., Khosla, S., Oursler, M. J. & Westendorf, J. J., Jan 1 2016, In : Journal of Bone and Mineral Research. 31, 1, p. 116-128 13 p.

Research output: Contribution to journalArticle

33 Scopus citations

Histone deacetylase 3 supports endochondral bone formation by controlling cytokine signaling and matrix remodeling

Carpio, L. R., Bradley, E. W., McGee Lawrence, M. E., Weivoda, M. M., Poston, D. D., Dudakovic, A., Xu, M., Tchkonia, T., Kirkland, J. L., Van Wijnen, A. J., Oursler, M. J. & Westendorf, J. J., Aug 9 2016, In : Science Signaling. 9, 440, ra79.

Research output: Contribution to journalArticle

28 Scopus citations

Phlpp1 facilitates post-traumatic osteoarthritis and is induced by inflammation and promoter demethylation in human osteoarthritis

Bradley, E. W., Carpio, L. R., McGee-Lawrence, M. E., Castillejo Becerra, C., Amanatullah, D. F., Ta, L. E., Otero, M., Goldring, M. B., Kakar, S. & Westendorf, J. J., Jun 1 2016, In : Osteoarthritis and Cartilage. 24, 6, p. 1021-1028 8 p.

Research output: Contribution to journalArticle

17 Scopus citations