• 1414 Citations
  • 22 h-Index
20052019
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Research Output 2005 2019

Article
13 Citations (Scopus)

Aberrant bone density in aging mice lacking the adenosine transporter ENT1

Hinton, D. J., McGee Lawrence, M. E., Lee, M. R., Kwong, H. K., Westendorf, J. J. & Choi, D. S., Feb 19 2014, In : PLoS One. 9, 2, e88818.

Research output: Contribution to journalArticle

bone density
adenosine
Bone Density
transporters
Bone
6 Citations (Scopus)

Arctic ground squirrels limit bone loss during the prolonged physical inactivity associated with hibernation

Wojda, S. J., Gridley, R. A., McGee Lawrence, M. E., Drummer, T. D., Hess, A., Kohl, F., Barnes, B. M. & Donahue, S. W., Jan 1 2016, In : Physiological and Biochemical Zoology. 89, 1, p. 72-80 9 p.

Research output: Contribution to journalArticle

Hibernation
Sciuridae
squirrels
hibernation
Arctic region
10 Citations (Scopus)

Black bear femoral geometry and cortical porosity are not adversely affected by ageing despite annual periods of disuse (hibernation)

McGee Lawrence, M. E., Miller, D. L., Auger, J., Black, H. L. & Donahue, S. W., Feb 1 2007, In : Journal of Anatomy. 210, 2, p. 160-169 10 p.

Research output: Contribution to journalArticle

Ursidae
Hibernation
hibernation
Porosity
thighs
9 Citations (Scopus)

Black bear femoral porosity decreases and mechanical properties increase with age despite annual periods of disuse (hibernation)

McGee Lawrence, M. E., Magic, K. W., Miller, D. L., Maki, A. J. & Donahue, S. W., Aug 1 2007, In : Engineering Fracture Mechanics. 74, 12, p. 1942-1952 11 p.

Research output: Contribution to journalArticle

Bone
Porosity
Mechanical properties
Minerals
Materials properties
11 Citations (Scopus)

Black bear parathyroid hormone has greater anabolic effects on trabecular bone in dystrophin-deficient mice than in wild type mice

Gray, S. K., McGee Lawrence, M. E., Sanders, J. L., Condon, K. W., Tsai, C. J. & Donahue, S. W., Sep 1 2012, In : Bone. 51, 3, p. 578-585 8 p.

Research output: Contribution to journalArticle

Ursidae
Anabolic Agents
Dystrophin
Parathyroid Hormone
Inbred mdx Mouse
7 Citations (Scopus)

Black bears with longer disuse (hibernation) periods have lower femoral osteon population density and greater mineralization and intracortical porosity

Wojda, S. J., Weyland, D. R., Gray, S. K., McGee Lawrence, M. E., Drummer, T. D. & Donahue, S. W., Aug 1 2013, In : Anatomical Record. 296, 8, p. 1148-1153 6 p.

Research output: Contribution to journalArticle

Haversian System
Ursidae
Hibernation
hibernation
Porosity

Commonly used adjuvants (liquid soap, foam sanitizer, or ultrasound gel) do not improve strength or curing time of fiberglass cast material

Meng, M. R. I., Elphingstone, J. W., Sinkler, M. A., Byrd, B. M. & McGee Lawrence, M. E., May 30 2019, In : Journal of Orthopaedic Surgery and Research. 14, 1, 166.

Research output: Contribution to journalArticle

Open Access
Surgical Casts
Soaps
Gels
Hand Sanitizers
Water
37 Citations (Scopus)

Decreased bone turnover with balanced resorption and formation prevent cortical bone loss during disuse (hibernation) in grizzly bears (Ursus arctos horribilis)

McGee Lawrence, M. E., Maki, A. J., Johnson, S. E., Nelson, O. L., Robbins, C. T. & Donahue, S. W., Feb 1 2008, In : Bone. 42, 2, p. 396-404 9 p.

Research output: Contribution to journalArticle

Ursidae
Hibernation
Bone Remodeling
Bone and Bones
Femur
4 Citations (Scopus)

Defining osteoblast and adipocyte lineages in the bone marrow

Pierce, J. L., Begun, D. L., Westendorf, J. J. & McGee Lawrence, M. E., Jan 1 2019, In : Bone. 118, p. 2-7 6 p.

Research output: Contribution to journalArticle

Osteoblasts
Mesenchymal Stromal Cells
Adipocytes
Bone Marrow
Osteogenesis
16 Citations (Scopus)

Deletion of Estrogen Receptor Beta in Osteoprogenitor Cells Increases Trabecular but Not Cortical Bone Mass in Female Mice

Nicks, K. M., Fujita, K., Fraser, D., McGregor, U., Drake, M. T., McGee Lawrence, M. E., Westendorf, J. J., Monroe, D. G. & Khosla, S., Mar 1 2016, In : Journal of Bone and Mineral Research. 31, 3, p. 606-614 9 p.

Research output: Contribution to journalArticle

Estrogen Receptor beta
Osteoblasts
Bone and Bones
Bone Remodeling
Bone Resorption
1 Citation (Scopus)
Osteogenesis
Bone Density
Protein Kinases
Minerals
Bone
3 Citations (Scopus)

Effects of calcium-loading on egg production in ring-necked pheasants

Jones, L. R., Black, H. L., White, C. M., Paul Johnston, N., McGee Lawrence, M. E., Donahue, S. W. & Eggett, D. L., Aug 1 2010, In : Journal of Wildlife Management. 74, 6, p. 1295-1300 6 p.

Research output: Contribution to journalArticle

Phasianus colchicus
egg production
calcium
pheasants
effect
4 Citations (Scopus)

Enhanced prostacyclin formation and Wnt signaling in sclerostin deficient osteocytes and bone

Ryan, Z. C., Craig, T. A., Salisbury, J. L., Carpio, L. R., McGee Lawrence, M. E., Westendorf, J. J. & Kumar, R., May 23 2014, In : Biochemical and Biophysical Research Communications. 448, 1, p. 83-88 6 p.

Research output: Contribution to journalArticle

Osteocytes
Epoprostenol
Bone
Bone and Bones
Osteoblasts
6 Citations (Scopus)

Enhancer of zeste homolog 2 (Ezh2) controls bone formation and cell cycle progression during osteogenesis in mice

Dudakovic, A., Camilleri, E. T., Paradise, C. R., Samsonraj, R. M., Gluscevic, M., Paggi, C. A., Begun, D. L., Khani, F., Pichurin, O., Ahmed, F. S., Elsayed, R., Elsalanty, M. E., McGee Lawrence, M. E., Karperien, M., Riester, S. M., Thaler, R., Westendorf, J. J. & Van Wijnen, A. J., Jan 1 2018, In : Journal of Biological Chemistry. 293, 33, p. 12894-12907 14 p.

Research output: Contribution to journalArticle

Osteogenesis
Cell Cycle
Bone
Cells
Osteoblasts
18 Citations (Scopus)

Enhancer of zeste homolog 2 inhibition stimulates bone formation and mitigates bone loss caused by ovariectomy in skeletally mature mice

Dudakovic, A., Camilleri, E. T., Riester, S. M., Paradise, C. R., Gluscevic, M., O'Toole, T. M., Thaler, R., Evans, J. M., Yan, H., Subramaniam, M., Hawse, J. R., Stein, G. S., Montecino, M. A., McGee Lawrence, M. E., Westendorf, J. J. & Van Wijnen, A. J., Nov 18 2016, In : Journal of Biological Chemistry. 291, 47, p. 24594-24606 13 p.

Research output: Contribution to journalArticle

Ovariectomy
Osteogenesis
Bone
Bone and Bones
Paracrine Communication
49 Citations (Scopus)

Epigenetic control of skeletal development by the histone methyltransferase Ezh2

Dudakovic, A., Camilleri, E. T., Xu, F., Riester, S. M., McGee Lawrence, M. E., Bradley, E. W., Paradise, C. R., Lewallen, E. A., Thaler, R., Deyle, D. R., Larson, A. N., Lewallen, D. G., Dietz, A. B., Stein, G. S., Montecino, M. A., Westendorf, J. J. & Van Wijnen, A. J., Nov 13 2015, In : Journal of Biological Chemistry. 290, 46, p. 27604-27617 14 p.

Research output: Contribution to journalArticle

Osteoblasts
Epigenomics
Bone
Polycomb-Group Proteins
Extracellular Matrix Proteins
37 Citations (Scopus)

Grizzly bears (Ursus arctos horribilis) and black bears (Ursus americanus) prevent trabecular bone loss during disuse (hibernation)

McGee Lawrence, M. E., Wojda, S. J., Barlow, L. N., Drummer, T. D., Castillo, A. B., Kennedy, O., Condon, K. W., Auger, J., Black, H. L., Nelson, O. L., Robbins, C. T. & Donahue, S. W., Dec 1 2009, In : Bone. 45, 6, p. 1186-1191 6 p.

Research output: Contribution to journalArticle

Ursidae
Hibernation
Bone and Bones
Bone Resorption
Osteogenesis
22 Citations (Scopus)

Hdac3 Deficiency Increases Marrow Adiposity and Induces Lipid Storage and Glucocorticoid Metabolism in Osteochondroprogenitor Cells

McGee Lawrence, M. E., Carpio, L. R., Schulze, R. J., Pierce, J. L., McNiven, M. A., Farr, J. N., Khosla, S., Oursler, M. J. & Westendorf, J. J., Jan 1 2016, In : Journal of Bone and Mineral Research. 31, 1, p. 116-128 13 p.

Research output: Contribution to journalArticle

Adiposity
Glucocorticoids
Bone Marrow
Lipids
Osteoblasts
31 Citations (Scopus)

Hibernating bears as a model for preventing disuse osteoporosis

Donahue, S. W., McGee Lawrence, M. E., Harvey, K. B., Vaughan, M. R. & Robbins, C. T., Aug 28 2006, In : Journal of Biomechanics. 39, 8, p. 1480-1488 9 p.

Research output: Contribution to journalArticle

Ursidae
Osteoporosis
Bone
Porosity
Hibernation
64 Citations (Scopus)

Histone deacetylase 3 depletion in osteo/chondroprogenitor cells decreases bone density and increases marrow fat

Razidlo, D. F., Whitney, T. J., Casper, M. E., McGee Lawrence, M. E., Stensgard, B. A., Li, X., Secreto, F. J., Knutson, S. K., Hiebert, S. W. & Westendorf, J. J., Aug 13 2010, In : PLoS One. 5, 7, e11492.

Research output: Contribution to journalArticle

histone deacetylase
bone density
Osteogenesis
Bone Density
Bone
43 Citations (Scopus)

Histone deacetylase 3 is required for maintenance of bone mass during aging

McGee Lawrence, M. E., Bradley, E. W., Dudakovic, A., Carlson, S. W., Ryan, Z. C., Kumar, R., Dadsetan, M., Yaszemski, M. J., Chen, Q., An, K. N. & Westendorf, J. J., Jan 1 2013, In : Bone. 52, 1, p. 296-307 12 p.

Research output: Contribution to journalArticle

Maintenance
Bone and Bones
Osteocalcin
Knockout Mice
Osteoblasts
21 Citations (Scopus)

Histone deacetylase 3 supports endochondral bone formation by controlling cytokine signaling and matrix remodeling

Carpio, L. R., Bradley, E. W., McGee Lawrence, M. E., Weivoda, M. M., Poston, D. D., Dudakovic, A., Xu, M., Tchkonia, T., Kirkland, J. L., Van Wijnen, A. J., Oursler, M. J. & Westendorf, J. J., Aug 9 2016, In : Science Signaling. 9, 440, ra79.

Research output: Contribution to journalArticle

Chondrocytes
Janus Kinases
Osteogenesis
Bone
Genes
28 Citations (Scopus)

Histone deacetylase inhibition destabilizes the multi-potent state of uncommitted adipose-derived mesenchymal stromal cells

Dudakovic, A., Camilleri, E. T., Lewallen, E. A., McGee Lawrence, M. E., Riester, S. M., Kakar, S., Montecino, M., Stein, G. S., Ryoo, H. M., Dietz, A. B., Westendorf, J. J. & Van Wijnen, A. J., Jan 1 2015, In : Journal of Cellular Physiology. 230, 1, p. 52-62 11 p.

Research output: Contribution to journalArticle

Histone Deacetylases
Mesenchymal Stromal Cells
Cells
Histone Deacetylase Inhibitors
Platelets
42 Citations (Scopus)

Histone deacetylase inhibition promotes osteoblast maturation by altering the histone H4 epigenome and reduces akt phosphorylation

Dudakovic, A., Evans, J. M., Li, Y., Middha, S., McGee Lawrence, M. E., Van Wijnen, A. J. & Westendorf, J. J., Oct 4 2013, In : Journal of Biological Chemistry. 288, 40, p. 28783-28791 9 p.

Research output: Contribution to journalArticle

Acetylation
Phosphorylation
Histone Deacetylases
Osteoblasts
Epigenomics
42 Citations (Scopus)

Histone deacetylases in bone development and skeletal disorders

Bradley, E. W., Carpio, L. R., Van Wijnen, A. J., McGee-Lawrence, M. E. & Westendorf, J. J., Sep 9 2015, In : Physiological reviews. 95, 4, p. 1359-1381 23 p.

Research output: Contribution to journalArticle

Sirtuins
Histone Deacetylases
Bone Development
Bone and Bones
Bone Density
1 Citation (Scopus)

Induction of fully stabilized cortical bone defects to study intramembranous bone regeneration

McGee Lawrence, M. E. & Razidlo, D. F., Jan 1 2015, In : Methods in Molecular Biology. 1226, p. 183-192 10 p.

Research output: Contribution to journalArticle

Bone Regeneration
Fracture Healing
Genetic Models
Skeleton
Femur
1 Citation (Scopus)

Inhibition of Osteocyte Membrane Repair Activity via Dietary Vitamin E Deprivation Impairs Osteocyte Survival

Hagan, M. L., Bahraini, A., Pierce, J. L., Bass, S. M., Yu, K., Elsayed, R., Elsalanty, M. E., Johnson, M. H., McNeil, A., McNeil, P. L. & McGee Lawrence, M. E., Feb 15 2019, In : Calcified Tissue International. 104, 2, p. 224-234 11 p.

Research output: Contribution to journalArticle

Osteocytes
Vitamin E
Cell Membrane
Membranes
Diet
14 Citations (Scopus)

Kynurenine, a Tryptophan Metabolite That Accumulates With Age, Induces Bone Loss

Refaey, M. E., McGee Lawrence, M. E., Fulzele, S. T., Kennedy, E. J., Bollag, W. B., Elsalanty, M. E., Zhong, Q., Ding, K., Bendzunas, N. G., Shi, X. M., Xu, J., Hill, W. D., Johnson, M. H., Hunter, D. M., Pierce, J. L., Yu, K., Hamrick, M. W. & Isales, C. M., Nov 1 2017, In : Journal of Bone and Mineral Research. 32, 11, p. 2182-2193 12 p.

Research output: Contribution to journalArticle

Kynurenine
Tryptophan
Bone and Bones
Aromatic Amino Acids
Anabolic Agents
2 Citations (Scopus)

Loss of Hdac3 in osteoprogenitors increases bone expression of osteoprotegerin, improving systemic insulin sensitivity

McGee Lawrence, M. E., Pierce, J. L., Yu, K., Culpepper, N. R., Bradley, E. W. & Westendorf, J. J., Apr 1 2018, In : Journal of Cellular Physiology. 233, 4, p. 2671-2680 10 p.

Research output: Contribution to journalArticle

Osteoprotegerin
Insulin Resistance
Bone
Insulin
Receptor Activator of Nuclear Factor-kappa B
3 Citations (Scopus)

Loss of histone methyltransferase Ezh2 stimulates an osteogenic transcriptional program in chondrocytes but does not affect cartilage development

Camilleri, E. T., Dudakovic, A., Riester, S. M., Galeano-Garces, C., Paradise, C. R., Bradley, E. W., McGee Lawrence, M. E., Im, H. J., Karperien, M., Krych, A. J., Westendorf, J. J., Noelle Larson, A. & Van Wijnen, A. J., Jan 1 2018, In : Journal of Biological Chemistry. 293, 49, p. 19001-19011 11 p.

Research output: Contribution to journalArticle

Cartilage
Chondrocytes
Bone
RNA
Histology
7 Citations (Scopus)

Mechanical loading disrupts osteocyte plasma membranes which initiates mechanosensation events in bone

Yu, K., Sellman, D. P., Bahraini, A., Hagan, M. L., Elsherbini, A., Vanpelt, K. T., Marshall, P. L., Hamrick, M. W., McNeil, A., McNeil, P. L. & McGee Lawrence, M. E., Feb 1 2018, In : Journal of Orthopaedic Research. 36, 2, p. 653-662 10 p.

Research output: Contribution to journalArticle

Osteocytes
Cell Membrane
Bone and Bones
Calcium Signaling
Weight-Bearing
4 Citations (Scopus)

Mimicking the effects of spaceflight on bone: Combined effects of disuse and chronic low-dose rate radiation exposure on bone mass in mice

Yu, K., Doherty, A. H., Genik, P. C., Gookin, S. E., Roteliuk, D. M., Wojda, S. J., Jiang, Z. S., McGee Lawrence, M. E., Weil, M. M. & Donahue, S. W., Nov 1 2017, In : Life Sciences in Space Research. 15, p. 62-68 7 p.

Research output: Contribution to journalArticle

hindlimb suspension
Hindlimb Suspension
Space Flight
radiation exposure
radiation dosage
1 Citation (Scopus)

Neutralization of CD40 ligand costimulation promotes bone formation and accretion of vertebral bone mass in mice

Roser-Page, S., Vikulina, T., Yu, K., McGee Lawrence, M. E. & Weitzmann, M. N., Jun 1 2018, In : Rheumatology (United Kingdom). 57, 6, p. 1105-1114 10 p.

Research output: Contribution to journalArticle

CD40 Ligand
Osteogenesis
Bone and Bones
Bone Remodeling
Skeleton
20 Citations (Scopus)

Osteoblasts protect AML cells from SDF-1-induced apoptosis

Kremer, K. N., Dudakovic, A., McGee Lawrence, M. E., Philips, R. L., Hess, A. D., Smith, B. D., Van Wijnen, A. J., Karp, J. E., Kaufmann, S. H., Westendorf, J. J. & Hedin, K. E., Jan 1 2014, In : Journal of Cellular Biochemistry. 115, 6, p. 1128-1137 10 p.

Research output: Contribution to journalArticle

Osteoblasts
Myeloid Cells
Acute Myeloid Leukemia
Bone
Apoptosis
55 Citations (Scopus)

Parathyroid hormone may maintain bone formation in hibernating black bears (Ursus americanus) to prevent disuse osteoporosis

Donahue, S. W., Galley, S. A., Vaughan, M. R., Patterson-Buckendahl, P., Demers, L. M., Vance, J. L. & McGee Lawrence, M. E., May 1 2006, In : Journal of Experimental Biology. 209, 9, p. 1630-1638 9 p.

Research output: Contribution to journalArticle

Ursidae
Hibernation
Ursus americanus
parathyroid hormone
hibernation
16 Citations (Scopus)

Phlpp1 facilitates post-traumatic osteoarthritis and is induced by inflammation and promoter demethylation in human osteoarthritis

Bradley, E. W., Carpio, L. R., McGee Lawrence, M. E., Castillejo Becerra, C., Amanatullah, D. F., Ta, L. E., Otero, M., Goldring, M. B., Kakar, S. & Westendorf, J. J., Jun 1 2016, In : Osteoarthritis and Cartilage. 24, 6, p. 1021-1028 8 p.

Research output: Contribution to journalArticle

Cartilage
Osteoarthritis
Methylation
Inflammation
Chondrocytes

Protein kinase D1 conditional null mice show minimal bone loss following ovariectomy

Bollag, W. B., Ding, K., Choudhary, V., Xu, J., Zhong, Q., Elsayed, R., Bailey, L. J., Elsalanty, M. E., Yu, K., Johnson, M. H., McGee Lawrence, M. E. & Isales, C. M., Oct 15 2018, In : Molecular and Cellular Endocrinology. 474, p. 176-183 8 p.

Research output: Contribution to journalArticle

Ovariectomy
Protein Kinases
Bone
Bone and Bones
Knockout Mice

Reduced bone formation in males and increased bone resorption in females drive bone loss in hemophilia A mice

Neale Weitzmann, M., Roser-Page, S., Vikulina, T., Weiss, D., Hao, L., Hunter Baldwin, W., Yu, K., del Mazo Arbona, N., McGee Lawrence, M. E., Meeks, S. L. & Kempton, C. L., Feb 12 2019, In : Blood Advances. 3, 3, p. 288-300 13 p.

Research output: Contribution to journalArticle

Hemophilia A
Bone Resorption
Osteogenesis
Bone and Bones
Skeleton
4 Citations (Scopus)

Regulation of the Glycerol Transporter, Aquaporin-3, by Histone Deacetylase-3 and p53 in Keratinocytes

Choudhary, V., Olala, L. O., Kagha, K., Pan, Z. Q., Chen, X., Yang, R., Cline, A., Helwa, I., Marshall, L., Kaddour-Djebbar, I., McGee-Lawrence, M. E. & Bollag, W. B., Sep 1 2017, In : Journal of Investigative Dermatology. 137, 9, p. 1935-1944 10 p.

Research output: Contribution to journalArticle

Aquaporin 3
Histone Deacetylase Inhibitors
Keratinocytes
Glycerol
Skin Diseases
21 Citations (Scopus)

Runx2 is required for early stages of endochondral bone formation but delays final stages of bone repair in Axin2-deficient mice

McGee Lawrence, M. E., Carpio, L. R., Bradley, E. W., Dudakovic, A., Lian, J. B., van Wijnen, A. J., Kakar, S., Hsu, W. & Westendorf, J. J., Jan 1 2014, In : Bone. 66, p. 277-286 10 p.

Research output: Contribution to journalArticle

Osteogenesis
Bone and Bones
Cleidocranial Dysplasia
Bony Callus
Chondrocytes
23 Citations (Scopus)

Runx2 protein represses axin2 expression in osteoblasts and is required for craniosynostosis in axin2-deficient mice

McGee Lawrence, M. E., Li, X., Bledsoe, K. L., Wu, H., Hawse, J. R., Subramaniam, M., Razidlo, D. F., Stensgard, B. A., Stein, G. S., Van Wijnen, A. J., Lian, J. B., Hsu, W. & Westendorf, J. J., Feb 22 2013, In : Journal of Biological Chemistry. 288, 8, p. 5291-5302 12 p.

Research output: Contribution to journalArticle

Core Binding Factor Alpha 1 Subunit
Cranial Sutures
Craniosynostoses
Osteoblasts
Osteogenesis
8 Citations (Scopus)

RUNX3 facilitates growth of Ewing sarcoma cells

Bledsoe, K. L., McGee Lawrence, M. E., Camilleri, E. T., Wang, X., Riester, S. M., van Wijnen, A. J., Oliveira, A. M. & Westendorf, J. J., Jan 1 2014, In : Journal of Cellular Physiology. 229, 12, p. 2049-2056 8 p.

Research output: Contribution to journalArticle

Ewing's Sarcoma
Tumors
Bone
Transcription Factors
Pediatrics
6 Citations (Scopus)
Scapula
Arthroplasty
Bone Density
Incidence
Therapeutics
67 Citations (Scopus)

Sclerostin alters serum vitamin D metabolite and fibroblast growth factor 23 concentrations and the urinary excretion of calcium

Ryan, Z. C., Ketha, H., McNulty, M. S., McGee Lawrence, M. E., Craig, T. A., Grande, J. P., Westendorf, J. J., Singh, R. J. & Kumar, R., Apr 9 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 15, p. 6199-6204 6 p.

Research output: Contribution to journalArticle

Knockout Mice
Vitamin D
Calcium
Serum
Galactosidases
28 Citations (Scopus)

Sclerostin deficient mice rapidly heal bone defects by activating β-catenin and increasing intramembranous ossification

McGee Lawrence, M. E., Ryan, Z. C., Carpio, L. R., Kakar, S., Westendorf, J. J. & Kumar, R., Nov 29 2013, In : Biochemical and Biophysical Research Communications. 441, 4, p. 886-890 5 p.

Research output: Contribution to journalArticle

Catenins
Osteogenesis
Bone
Bone and Bones
Defects
29 Citations (Scopus)

Six months of disuse during hibernation does not increase intracortical porosity or decrease cortical bone geometry, strength, or mineralization in black bear (Ursus americanus) femurs

McGee Lawrence, M. E., Wojda, S. J., Barlow, L. N., Drummer, T. D., Bunnell, K., Auger, J., Black, H. L. & Donahue, S. W., Jul 22 2009, In : Journal of Biomechanics. 42, 10, p. 1378-1383 6 p.

Research output: Contribution to journalArticle

Ursidae
Hibernation
Porosity
Femur
Bone
47 Citations (Scopus)

Suberoylanilide hydroxamic acid (SAHA; vorinostat) causes bone loss by inhibiting immature osteoblasts

McGee Lawrence, M. E., McCleary-Wheeler, A. L., Secreto, F. J., Razidlo, D. F., Zhang, M., Stensgard, B. A., Li, X., Stein, G. S., Lian, J. B. & Westendorf, J. J., May 1 2011, In : Bone. 48, 5, p. 1117-1126 10 p.

Research output: Contribution to journalArticle

Osteoblasts
Bone and Bones
Histone Deacetylase Inhibitors
Osteogenesis
Epilepsy
22 Citations (Scopus)

Suppressed bone remodeling in black bears conserves energy and bone mass during hibernation

McGee-Lawrence, M., Buckendahl, P., Carpenter, C., Henriksen, K., Vaughan, M. & Donahue, S., Jul 1 2015, In : Journal of Experimental Biology. 218, 13, p. 2067-2074 8 p.

Research output: Contribution to journalArticle

Ursidae
Hibernation
hibernation
Bone Remodeling
bone
23 Citations (Scopus)

The Ewing's sarcoma fusion protein, EWS-FLI, binds Runx2 and blocks osteoblast differentiation

Li, X., McGee Lawrence, M. E., Decker, M. & Westendorf, J. J., Nov 1 2010, In : Journal of cellular biochemistry. 111, 4, p. 933-943 11 p.

Research output: Contribution to journalArticle

Ewing's Sarcoma
Osteoblasts
Tumors
Bone and Bones
Neoplasms
30 Citations (Scopus)

The histone deacetylase inhibitor, vorinostat, reduces tumor growth at the metastatic bone site and associated osteolysis, but promotes normal bone loss

Pratap, J., Akech, J., Wixted, J. J., Szabo, G., Hussain, S., McGee Lawrence, M. E., Li, X., Bedard, K., Dhillon, R. J., Van Wijnen, A. J., Stein, J. L., Stein, G. S., Westendorf, J. J. & Lian, J. B., Dec 1 2010, In : Molecular cancer therapeutics. 9, 12, p. 3210-3220 11 p.

Research output: Contribution to journalArticle

Osteolysis
Histone Deacetylase Inhibitors
Bone and Bones
Growth
Neoplasms