• 1635 Citations
  • 25 h-Index
20052020

Research output per year

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Research Output

Article

Aberrant bone density in aging mice lacking the adenosine transporter ENT1

Hinton, D. J., McGee-Lawrence, M. E., Lee, M. R., Kwong, H. K., Westendorf, J. J. & Choi, D. S., Feb 19 2014, In : PloS one. 9, 2, e88818.

Research output: Contribution to journalArticle

14 Scopus citations

Age-related increase of kynurenine enhances miR29b-1-5p to decrease both CXCL12 signaling and the epigenetic enzyme Hdac3 in bone marrow stromal cells

Elmansi, A. M., Hussein, K. A., Herrero, S. M., Periyasamy-Thandavan, S., Aguilar-Pérez, A., Kondrikova, G., Kondrikov, D. Y., Eisa, N. H., Pierce, J. L., Kaiser, H., Ding, K. H., Walker, A. L., Jiang, X., Bollag, W. B., Elsalanty, M. E., Zhong, Q., Shi, X. M., Su, Y., Johnson, M., Hunter, M. & 7 others, Reitman, C., Volkman, B. F., Hamrick, M. W., Isales, C. M., Fulzele, S., McGee-Lawrence, M. E. & Hill, W. D., Jun 2020, In : Bone Reports. 12, 100270.

Research output: Contribution to journalArticle

Open Access

Arctic ground squirrels limit bone loss during the prolonged physical inactivity associated with hibernation

Wojda, S. J., Gridley, R. A., McGee Lawrence, M. E., Drummer, T. D., Hess, A., Kohl, F., Barnes, B. M. & Donahue, S. W., Jan 1 2016, In : Physiological and Biochemical Zoology. 89, 1, p. 72-80 9 p.

Research output: Contribution to journalArticle

8 Scopus citations

Black bear femoral geometry and cortical porosity are not adversely affected by ageing despite annual periods of disuse (hibernation)

McGee, M. E., Miller, D. L., Auger, J., Black, H. L. & Donahue, S. W., Feb 1 2007, In : Journal of Anatomy. 210, 2, p. 160-169 10 p.

Research output: Contribution to journalArticle

11 Scopus citations

Black bear femoral porosity decreases and mechanical properties increase with age despite annual periods of disuse (hibernation)

McGee, M. E., Magic, K. W., Miller, D. L., Maki, A. J. & Donahue, S. W., Aug 1 2007, In : Engineering Fracture Mechanics. 74, 12, p. 1942-1952 11 p.

Research output: Contribution to journalArticle

9 Scopus citations

Black bear parathyroid hormone has greater anabolic effects on trabecular bone in dystrophin-deficient mice than in wild type mice

Gray, S. K., McGee-Lawrence, M. E., Sanders, J. L., Condon, K. W., Tsai, C. J. & Donahue, S. W., Sep 1 2012, In : Bone. 51, 3, p. 578-585 8 p.

Research output: Contribution to journalArticle

12 Scopus citations

Black bears with longer disuse (hibernation) periods have lower femoral osteon population density and greater mineralization and intracortical porosity

Wojda, S. J., Weyland, D. R., Gray, S. K., Mcgee-Lawrence, M. E., Drummer, T. D. & Donahue, S. W., Aug 1 2013, In : Anatomical Record. 296, 8, p. 1148-1153 6 p.

Research output: Contribution to journalArticle

8 Scopus citations

Commonly used adjuvants (liquid soap, foam sanitizer, or ultrasound gel) do not improve strength or curing time of fiberglass cast material

Meng, M. R. I., Elphingstone, J. W., Sinkler, M. A., Byrd, B. M. & McGee-Lawrence, M. E., May 30 2019, In : Journal of Orthopaedic Surgery and Research. 14, 1, 166.

Research output: Contribution to journalArticle

Open Access

Decreased bone turnover with balanced resorption and formation prevent cortical bone loss during disuse (hibernation) in grizzly bears (Ursus arctos horribilis)

McGee Lawrence, M. E., Maki, A. J., Johnson, S. E., Nelson, O. L., Robbins, C. T. & Donahue, S. W., Feb 1 2008, In : Bone. 42, 2, p. 396-404 9 p.

Research output: Contribution to journalArticle

41 Scopus citations

Decreased pericellular matrix production and selection for enhanced cell membrane repair may impair osteocyte responses to mechanical loading in the aging skeleton

Hagan, M. L., Yu, K., Zhu, J., Vinson, B. N., Roberts, R. L., Montesinos Cartagena, M., Johnson, M. H., Wang, L., Isales, C. M., Hamrick, M. W., McNeil, P. L. & McGee-Lawrence, M. E., Jan 1 2020, In : Aging Cell. 19, 1, e13056.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Defining osteoblast and adipocyte lineages in the bone marrow

Pierce, J. L., Begun, D. L., Westendorf, J. J. & McGee-Lawrence, M. E., Jan 2019, In : Bone. 118, p. 2-7 6 p.

Research output: Contribution to journalArticle

8 Scopus citations

Deletion of Estrogen Receptor Beta in Osteoprogenitor Cells Increases Trabecular but Not Cortical Bone Mass in Female Mice

Nicks, K. M., Fujita, K., Fraser, D., McGregor, U., Drake, M. T., McGee-Lawrence, M. E., Westendorf, J. J., Monroe, D. G. & Khosla, S., Mar 1 2016, In : Journal of Bone and Mineral Research. 31, 3, p. 606-614 9 p.

Research output: Contribution to journalArticle

18 Scopus citations

Deletion of PPARγin Mesenchymal Lineage Cells Protects Against Aging-Induced Cortical Bone Loss in Mice

Cao, J., Ding, K., Pan, G., Rosario, R., Su, Y., Bao, Y., Zhou, H., Xu, J., McGee Lawrence, M. E., Hamrick, M. W., Isales, C. M. & Shi, X., Apr 17 2020, In : Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 75, 5, p. 826-834 9 p.

Research output: Contribution to journalArticle

1 Scopus citations

Effects of calcium-loading on egg production in ring-necked pheasants

Jones, L. R., Black, H. L., White, C. M., Paul Johnston, N., McGee, M. E., Donahue, S. W. & Eggett, D. L., Aug 1 2010, In : Journal of Wildlife Management. 74, 6, p. 1295-1300 6 p.

Research output: Contribution to journalArticle

3 Scopus citations

Elevated ceramides 18:0 and 24:1 with aging are associated with hip fracture risk through increased bone resorption

Kim, B. J., Lee, J. Y., Park, S. J., Lee, S. H., Kim, S. J., Yoo, H. J., De Pena, S. I. R., McGee-Lawrence, M., Isales, C. M., Koh, J. M. & Hamrick, M. W., Jan 1 2019, In : Aging. 11, 21, p. 9388-9404 17 p.

Research output: Contribution to journalArticle

Enhanced prostacyclin formation and Wnt signaling in sclerostin deficient osteocytes and bone

Ryan, Z. C., Craig, T. A., Salisbury, J. L., Carpio, L. R., McGee-Lawrence, M., Westendorf, J. J. & Kumar, R., May 23 2014, In : Biochemical and Biophysical Research Communications. 448, 1, p. 83-88 6 p.

Research output: Contribution to journalArticle

5 Scopus citations

Enhancer of zeste homolog 2 (Ezh2) controls bone formation and cell cycle progression during osteogenesis in mice

Dudakovic, A., Camilleri, E. T., Paradise, C. R., Samsonraj, R. M., Gluscevic, M., Paggi, C. A., Begun, D. L., Khani, F., Pichurin, O., Ahmed, F. S., Elsayed, R., Elsalanty, M. E., McGee Lawrence, M. E., Karperien, M., Riester, S. M., Thaler, R., Westendorf, J. J. & Van Wijnen, A. J., Aug 17 2018, In : Journal of Biological Chemistry. 293, 33, p. 12894-12907 14 p.

Research output: Contribution to journalArticle

9 Scopus citations

Enhancer of zeste homolog 2 inhibition stimulates bone formation and mitigates bone loss caused by ovariectomy in skeletally mature mice

Dudakovic, A., Camilleri, E. T., Riester, S. M., Paradise, C. R., Gluscevic, M., O'Toole, T. M., Thaler, R., Evans, J. M., Yan, H., Subramaniam, M., Hawse, J. R., Stein, G. S., Montecino, M. A., McGee Lawrence, M. E., Westendorf, J. J. & Van Wijnen, A. J., Nov 18 2016, In : Journal of Biological Chemistry. 291, 47, p. 24594-24606 13 p.

Research output: Contribution to journalArticle

26 Scopus citations

Epigenetic control of skeletal development by the histone methyltransferase Ezh2

Dudakovic, A., Camilleri, E. T., Xu, F., Riester, S. M., McGee Lawrence, M. E., Bradley, E. W., Paradise, C. R., Lewallen, E. A., Thaler, R., Deyle, D. R., Larson, A. N., Lewallen, D. G., Dietz, A. B., Stein, G. S., Montecino, M. A., Westendorf, J. J. & Van Wijnen, A. J., Nov 13 2015, In : Journal of Biological Chemistry. 290, 46, p. 27604-27617 14 p.

Research output: Contribution to journalArticle

65 Scopus citations

Grizzly bears (Ursus arctos horribilis) and black bears (Ursus americanus) prevent trabecular bone loss during disuse (hibernation)

McGee-Lawrence, M. E., Wojda, S. J., Barlow, L. N., Drummer, T. D., Castillo, A. B., Kennedy, O., Condon, K. W., Auger, J., Black, H. L., Nelson, O. L., Robbins, C. T. & Donahue, S. W., Dec 1 2009, In : Bone. 45, 6, p. 1186-1191 6 p.

Research output: Contribution to journalArticle

40 Scopus citations

Hdac3 Deficiency Increases Marrow Adiposity and Induces Lipid Storage and Glucocorticoid Metabolism in Osteochondroprogenitor Cells

McGee Lawrence, M. E., Carpio, L. R., Schulze, R. J., Pierce, J. L., McNiven, M. A., Farr, J. N., Khosla, S., Oursler, M. J. & Westendorf, J. J., Jan 1 2016, In : Journal of Bone and Mineral Research. 31, 1, p. 116-128 13 p.

Research output: Contribution to journalArticle

32 Scopus citations

Hibernating bears as a model for preventing disuse osteoporosis

Donahue, S. W., McGee, M. E., Harvey, K. B., Vaughan, M. R. & Robbins, C. T., Aug 28 2006, In : Journal of Biomechanics. 39, 8, p. 1480-1488 9 p.

Research output: Contribution to journalArticle

32 Scopus citations

Histone deacetylase 3 depletion in osteo/chondroprogenitor cells decreases bone density and increases marrow fat

Razidlo, D. F., Whitney, T. J., Casper, M. E., McGee-Lawrence, M. E., Stensgard, B. A., Li, X., Secreto, F. J., Knutson, S. K., Hiebert, S. W. & Westendorf, J. J., Aug 13 2010, In : PloS one. 5, 7, e11492.

Research output: Contribution to journalArticle

73 Scopus citations

Histone deacetylase 3 is required for maintenance of bone mass during aging

McGee Lawrence, M. E., Bradley, E. W., Dudakovic, A., Carlson, S. W., Ryan, Z. C., Kumar, R., Dadsetan, M., Yaszemski, M. J., Chen, Q., An, K. N. & Westendorf, J. J., Jan 1 2013, In : Bone. 52, 1, p. 296-307 12 p.

Research output: Contribution to journalArticle

49 Scopus citations

Histone deacetylase 3 supports endochondral bone formation by controlling cytokine signaling and matrix remodeling

Carpio, L. R., Bradley, E. W., McGee Lawrence, M. E., Weivoda, M. M., Poston, D. D., Dudakovic, A., Xu, M., Tchkonia, T., Kirkland, J. L., Van Wijnen, A. J., Oursler, M. J. & Westendorf, J. J., Aug 9 2016, In : Science Signaling. 9, 440, ra79.

Research output: Contribution to journalArticle

27 Scopus citations

Histone deacetylase inhibition destabilizes the multi-potent state of uncommitted adipose-derived mesenchymal stromal cells

Dudakovic, A., Camilleri, E. T., Lewallen, E. A., McGee Lawrence, M. E., Riester, S. M., Kakar, S., Montecino, M., Stein, G. S., Ryoo, H. M., Dietz, A. B., Westendorf, J. J. & Van Wijnen, A. J., Jan 1 2015, In : Journal of Cellular Physiology. 230, 1, p. 52-62 11 p.

Research output: Contribution to journalArticle

33 Scopus citations

Histone deacetylase inhibition promotes osteoblast maturation by altering the histone H4 epigenome and reduces akt phosphorylation

Dudakovic, A., Evans, J. M., Li, Y., Middha, S., McGee Lawrence, M. E., Van Wijnen, A. J. & Westendorf, J. J., Oct 4 2013, In : Journal of Biological Chemistry. 288, 40, p. 28783-28791 9 p.

Research output: Contribution to journalArticle

47 Scopus citations

Histone deacetylases in bone development and skeletal disorders

Bradley, E. W., Carpio, L. R., Van Wijnen, A. J., McGee-Lawrence, M. E. & Westendorf, J. J., Sep 9 2015, In : Physiological reviews. 95, 4, p. 1359-1381 23 p.

Research output: Contribution to journalArticle

50 Scopus citations

Induction of fully stabilized cortical bone defects to study intramembranous bone regeneration

McGee Lawrence, M. E. & Razidlo, D. F., Jan 1 2015, In : Methods in Molecular Biology. 1226, p. 183-192 10 p.

Research output: Contribution to journalArticle

Inhibition of Osteocyte Membrane Repair Activity via Dietary Vitamin E Deprivation Impairs Osteocyte Survival

Hagan, M. L., Bahraini, A., Pierce, J. L., Bass, S. M., Yu, K., Elsayed, R., Elsalanty, M., Johnson, M. H., McNeil, A., McNeil, P. L. & McGee-Lawrence, M. E., Feb 15 2019, In : Calcified Tissue International. 104, 2, p. 224-234 11 p.

Research output: Contribution to journalArticle

2 Scopus citations

Kynurenine, a Tryptophan Metabolite That Accumulates With Age, Induces Bone Loss

Refaey, M. E., McGee-Lawrence, M. E., Fulzele, S., Kennedy, E. J., Bollag, W. B., Elsalanty, M., Zhong, Q., Ding, K. H., Bendzunas, N. G., Shi, X. M., Xu, J., Hill, W. D., Johnson, M. H., Hunter, M., Pierce, J. L., Yu, K., Hamrick, M. W. & Isales, C. M., Nov 2017, In : Journal of Bone and Mineral Research. 32, 11, p. 2182-2193 12 p.

Research output: Contribution to journalArticle

27 Scopus citations
Open Access
3 Scopus citations

Kynurenine suppresses osteoblastic cell energetics in vitro and osteoblast numbers in vivo

Pierce, J. L., Roberts, R. L., Yu, K., Kendall, R. K., Kaiser, H., Davis, C., Johnson, M. H., Hill, W. D., Isales, C. M., Bollag, W. B., Hamrick, M. W. & McGee-Lawrence, M. E., Feb 2020, In : Experimental Gerontology. 130, 110818.

Research output: Contribution to journalArticle

1 Scopus citations

Loss of Hdac3 in osteoprogenitors increases bone expression of osteoprotegerin, improving systemic insulin sensitivity

McGee-Lawrence, M. E., Pierce, J. L., Yu, K., Culpepper, N. R., Bradley, E. W. & Westendorf, J. J., Apr 2018, In : Journal of Cellular Physiology. 233, 4, p. 2671-2680 10 p.

Research output: Contribution to journalArticle

3 Scopus citations

Loss of histone methyltransferase Ezh2 stimulates an osteogenic transcriptional program in chondrocytes but does not affect cartilage development

Camilleri, E. T., Dudakovic, A., Riester, S. M., Galeano-Garces, C., Paradise, C. R., Bradley, E. W., McGee Lawrence, M. E., Im, H. J., Karperien, M., Krych, A. J., Westendorf, J. J., Noelle Larson, A. & Van Wijnen, A. J., Dec 7 2018, In : Journal of Biological Chemistry. 293, 49, p. 19001-19011 11 p.

Research output: Contribution to journalArticle

6 Scopus citations

Mechanical loading disrupts osteocyte plasma membranes which initiates mechanosensation events in bone

Yu, K., Sellman, D. P., Bahraini, A., Hagan, M. L., Elsherbini, A., Vanpelt, K. T., Marshall, P. L., Hamrick, M. W., McNeil, A., McNeil, P. L. & McGee Lawrence, M. E., Feb 1 2018, In : Journal of Orthopaedic Research. 36, 2, p. 653-662 10 p.

Research output: Contribution to journalArticle

12 Scopus citations

Mimicking the effects of spaceflight on bone: Combined effects of disuse and chronic low-dose rate radiation exposure on bone mass in mice

Yu, K., Doherty, A. H., Genik, P. C., Gookin, S. E., Roteliuk, D. M., Wojda, S. J., Jiang, Z. S., McGee-Lawrence, M. E., Weil, M. M. & Donahue, S. W., Nov 2017, In : Life Sciences in Space Research. 15, p. 62-68 7 p.

Research output: Contribution to journalArticle

7 Scopus citations

Neutralization of CD40 ligand costimulation promotes bone formation and accretion of vertebral bone mass in mice

Roser-Page, S., Vikulina, T., Yu, K., McGee-Lawrence, M. E. & Weitzmann, M. N., Jun 1 2018, In : Rheumatology (United Kingdom). 57, 6, p. 1105-1114 10 p.

Research output: Contribution to journalArticle

1 Scopus citations

Osteoblasts protect AML cells from SDF-1-induced apoptosis

Kremer, K. N., Dudakovic, A., McGee Lawrence, M. E., Philips, R. L., Hess, A. D., Smith, B. D., Van Wijnen, A. J., Karp, J. E., Kaufmann, S. H., Westendorf, J. J. & Hedin, K. E., Jun 2014, In : Journal of cellular biochemistry. 115, 6, p. 1128-1137 10 p.

Research output: Contribution to journalArticle

21 Scopus citations

Parathyroid hormone may maintain bone formation in hibernating black bears (Ursus americanus) to prevent disuse osteoporosis

Donahue, S. W., Galley, S. A., Vaughan, M. R., Patterson-Buckendahl, P., Demers, L. M., Vance, J. L. & McGee, M. E., May 1 2006, In : Journal of Experimental Biology. 209, 9, p. 1630-1638 9 p.

Research output: Contribution to journalArticle

60 Scopus citations

Phlpp1 facilitates post-traumatic osteoarthritis and is induced by inflammation and promoter demethylation in human osteoarthritis

Bradley, E. W., Carpio, L. R., McGee-Lawrence, M. E., Castillejo Becerra, C., Amanatullah, D. F., Ta, L. E., Otero, M., Goldring, M. B., Kakar, S. & Westendorf, J. J., Jun 1 2016, In : Osteoarthritis and Cartilage. 24, 6, p. 1021-1028 8 p.

Research output: Contribution to journalArticle

17 Scopus citations

Picolinic acid, a tryptophan oxidation product, does not impact bone mineral density but increases marrow adiposity

Ding, K., McGee-Lawrence, M. E., Kaiser, H., Sharma, A. K., Pierce, J. L., Irsik, D. L., Bollag, W. B., Xu, J., Zhong, Q., Hill, W. D., Shi, X. M., Fulzele, S., Kennedy, E. J., Elsalanty, M. E., Hamrick, M. W. & Isales, C. M., May 2020, In : Experimental Gerontology. 133, 110885.

Research output: Contribution to journalArticle

1 Scopus citations

Protein kinase D1 conditional null mice show minimal bone loss following ovariectomy

Bollag, W. B., Ding, K., Choudhary, V., Xu, J., Zhong, Q., Elsayed, R., Bailey, L. J., Elsalanty, M. E., Yu, K., Johnson, M. H., McGee Lawrence, M. E. & Isales, C. M., Oct 15 2018, In : Molecular and Cellular Endocrinology. 474, p. 176-183 8 p.

Research output: Contribution to journalArticle

Reduced bone formation in males and increased bone resorption in females drive bone loss in hemophilia A mice

Neale Weitzmann, M., Roser-Page, S., Vikulina, T., Weiss, D., Hao, L., Hunter Baldwin, W., Yu, K., del Mazo Arbona, N., McGee Lawrence, M. E., Meeks, S. L. & Kempton, C. L., Feb 12 2019, In : Blood Advances. 3, 3, p. 288-300 13 p.

Research output: Contribution to journalArticle

2 Scopus citations

Regulation of the Glycerol Transporter, Aquaporin-3, by Histone Deacetylase-3 and p53 in Keratinocytes

Choudhary, V., Olala, L. O., Kagha, K., Pan, Z. Q., Chen, X., Yang, R., Cline, A., Helwa, I., Marshall, L., Kaddour-Djebbar, I., McGee-Lawrence, M. E. & Bollag, W. B., Sep 2017, In : Journal of Investigative Dermatology. 137, 9, p. 1935-1944 10 p.

Research output: Contribution to journalArticle

8 Scopus citations

Runx2 is required for early stages of endochondral bone formation but delays final stages of bone repair in Axin2-deficient mice

McGee Lawrence, M. E., Carpio, L. R., Bradley, E. W., Dudakovic, A., Lian, J. B., van Wijnen, A. J., Kakar, S., Hsu, W. & Westendorf, J. J., Sep 2014, In : Bone. 66, p. 277-286 10 p.

Research output: Contribution to journalArticle

26 Scopus citations

Runx2 protein represses axin2 expression in osteoblasts and is required for craniosynostosis in axin2-deficient mice

McGee Lawrence, M. E., Li, X., Bledsoe, K. L., Wu, H., Hawse, J. R., Subramaniam, M., Razidlo, D. F., Stensgard, B. A., Stein, G. S., Van Wijnen, A. J., Lian, J. B., Hsu, W. & Westendorf, J. J., Feb 22 2013, In : Journal of Biological Chemistry. 288, 8, p. 5291-5302 12 p.

Research output: Contribution to journalArticle

25 Scopus citations

RUNX3 facilitates growth of Ewing sarcoma cells

Bledsoe, K. L., Mcgee-Lawrence, M. E., Camilleri, E. T., Wang, X., Riester, S. M., van Wijnen, A. J., Oliveira, A. M. & Westendorf, J. J., Dec 2014, In : Journal of Cellular Physiology. 229, 12, p. 2049-2056 8 p.

Research output: Contribution to journalArticle

8 Scopus citations
15 Scopus citations