Menaka Thounaojam

Assistant Research Scientist

  • 1076 Citations
  • 20 h-Index
20092020
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Research Output 2009 2020

  • 1076 Citations
  • 20 h-Index
  • 62 Article
  • 5 Editorial
  • 2 Review article
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Article
2020

Carbon monoxide releasing molecule-A1 improves nonalcoholic steatohepatitis via Nrf2 activation mediated improvement in oxidative stress and mitochondrial function

Upadhyay, K. K., Jadeja, R. N., Vyas, H. S., Pandya, B., Joshi, A., Vohra, A., Thounaojam, M. C., Martin, P. M., Bartoli, M. & Devkar, R. V., Jan 2020, In : Redox Biology. 28, 101314.

Research output: Contribution to journalArticle

Open Access
Oxidative stress
Carbon Monoxide
Oxidative Stress
Chemical activation
Molecules
1 Citation (Scopus)
Open Access
Retinal Degeneration
Oxidative stress
Retinal Pigments
Retinal Pigment Epithelium
MicroRNAs
2019
1 Citation (Scopus)
Open Access
Cell Aging
Endothelial cells
MicroRNAs
Endothelial Cells
Antioxidants
1 Citation (Scopus)

Monosodium urate contributes to retinal inflammation and progression of diabetic retinopathy

Thounaojam, M., Montemari, A., Powell, F. L., Malla, P., Gutsaeva, D. R., Bachettoni, A., Ripandelli, G., Repossi, A., Tawfik, A. M., Martin, P. M., Facchiano, F. & Bartoli, M., Jan 1 2019, In : Diabetes. 68, 5, p. 1014-1025 12 p.

Research output: Contribution to journalArticle

Open Access
Diabetic Retinopathy
Uric Acid
Inflammation
Streptozocin
Hyperglycemia
8 Citations (Scopus)

Sapota fruit latex mediated synthesis of Ag, Cu mono and bimetallic nanoparticles and their in vitro toxicity studies

Thakore, S. I., Nagar, P. S., Jadeja, R. N., Thounaojam, M., Devkar, R. V. & Rathore, P. S., Jul 2019, In : Arabian Journal of Chemistry. 12, 5, p. 694-700 7 p.

Research output: Contribution to journalArticle

Open Access
Latex
Fruits
Latexes
Toxicity
Ascorbic acid
2018
Glycodeoxycholic Acid
rho-Associated Kinases
Bile Acids and Salts
Blood Vessels
15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid
3 Citations (Scopus)

Loss of NAMPT in aging retinal pigment epithelium reduces NAD+ availability and promotes cellular senescence

Jadeja, R. N., Powell, F. L., Jones, M. A., Fuller, J., Joseph, E., Thounaojam, M. C., Bartoli, M. & Martin, P. M., Jun 1 2018, In : Aging. 10, 6, p. 1306-1323 18 p.

Research output: Contribution to journalArticle

Nicotinamide Phosphoribosyltransferase
Retinal Pigment Epithelium
Cell Aging
NAD
Retinal Diseases
2017
3 Citations (Scopus)

Characterization of pressure-mediated vascular tone in resistance arteries from bile duct-ligated rats

Jadeja, R. N., Thounaojam, M. C. & Khurana, S., Jan 1 2017, In : Oncotarget. 8, 19, p. 30706-30722 17 p.

Research output: Contribution to journalArticle

Bile Ducts
Blood Vessels
Arteries
Pressure
Fibrosis
12 Citations (Scopus)
Growth Hormone-Releasing Hormone
Diabetic Retinopathy
Retina
Streptozocin
Hormone Antagonists
5 Citations (Scopus)

STAT3-mediated activation of miR-21 is involved in downregulation of TIMP3 and neovascularization in the ischemic retina

Gutsaeva, D. R., Thounaojam, M., Rajpurohit, S., Powell, F. L., Martin, P. M., Goei, S., Duncan, M. & Bartoli, M., Jan 1 2017, In : Oncotarget. 8, 61, p. 103568-103580 13 p.

Research output: Contribution to journalArticle

Tissue Inhibitor of Metalloproteinase-3
STAT3 Transcription Factor
Matrix Metalloproteinase 3
Retinal Neovascularization
MicroRNAs
2016
4 Citations (Scopus)

Oral Monomethyl Fumarate Therapy Ameliorates Retinopathy in a Humanized Mouse Model of Sickle Cell Disease

Promsote, W., Powell, F. L., Veean, S., Thounaojam, M., Markand, S., Saul, A., Gutsaeva, D., Bartoli, M., Smith, S. B., Ganapathy, V. & Martin, P. M., Dec 10 2016, In : Antioxidants and Redox Signaling. 25, 17, p. 921-935 15 p.

Research output: Contribution to journalArticle

Fumarates
Sickle Cell Anemia
Oxidative stress
Pathology
Oxidative Stress
2015
10 Citations (Scopus)

Bortezomib enhances expression of effector molecules in antitumor CD8+T lymphocytes by promoting Notch-nuclear factor-κB crosstalk

Thounaojam, M., Dudimah, D. F., Pellom, S. T., Uzhachenko, R. V., Carbone, D. P., Dikov, M. M. & Shanker, A., Jan 1 2015, In : Oncotarget. 6, 32, p. 32439-32455 17 p.

Research output: Contribution to journalArticle

Complement Factor B
T-Lymphocytes
Neoplasms
Immunosuppressive Agents
Notch Receptors
9 Citations (Scopus)

Bortezomib improves adoptive T-Cell therapy by sensitizing cancer cells to FasL cytotoxicity

Shanker, A., Pellom, S. T., Dudimah, D. F., Thounaojam, M., De Kluyver, R. L., Brooks, A. D., Yagita, H., McVicar, D. W., Murphy, W. J., Longo, D. L. & Sayers, T. J., Dec 15 2015, In : Cancer Research. 75, 24, p. 5260-5272 13 p.

Research output: Contribution to journalArticle

Cell- and Tissue-Based Therapy
T-Lymphocytes
Neoplasms
Immunotherapy
Proteasome Inhibitors

From immunogenetic polymorphism to functional antitumor lymphocyte mitochondrial dynamics

Uzhachenko, R., Thounaojam, M. & Shanker, A., Jan 1 2015, In : Journal for ImmunoTherapy of Cancer. 3, O13.

Research output: Contribution to journalArticle

Mitochondrial Dynamics
Immunogenetics
Lymphocytes
2014
69 Citations (Scopus)

MicroRNA 155 regulates Japanese encephalitis virus-induced inflammatory response by targeting Src homology 2-containing inositol phosphatase 1

Thounaojam, M. C., Kundu, K., Kaushik, D. K., Swaroop, S., Mahadevan, A., Shankar, S. K. & Basu, A., May 2014, In : Journal of Virology. 88, 9, p. 4798-4810 13 p.

Research output: Contribution to journalArticle

Japanese Encephalitis Virus
Japanese encephalitis virus
MicroRNAs
microRNA
inflammation
49 Citations (Scopus)

MicroRNA-29b modulates Japanese encephalitis virus-induced microglia activation by targeting tumor necrosis factor alpha-induced protein 3

Thounaojam, M., Kaushik, D. K., Kundu, K. & Basu, A., Jan 1 2014, In : Journal of Neurochemistry. 129, 1, p. 143-154 12 p.

Research output: Contribution to journalArticle

Japanese Encephalitis Virus
Microglia
MicroRNAs
Viruses
Tumor Necrosis Factor-alpha
12 Citations (Scopus)

Sunflower oil mediated biomimetic synthesis and cytotoxicity of monodisperse hexagonal silver nanoparticles

Thakore, S., Rathore, P. S., Jadeja, R. N., Thounaojam, M. & Devkar, R. V., Nov 1 2014, In : Materials Science and Engineering C. 44, p. 209-215 7 p.

Research output: Contribution to journalArticle

sunflowers
Sunflower oil
biomimetics
Biomimetics
Cytotoxicity
1 Citation (Scopus)
Wasp Venoms
Venoms
Microglia
Chemokines
Lipopolysaccharides
2013
25 Citations (Scopus)

Interleukin-1β orchestrates underlying inflammatory responses in microglia via Krüppel-like factor 4

Kaushik, D. K., Thounaojam, M. C., Kumawat, K. L., Gupta, M. & Basu, A., Oct 1 2013, In : Journal of Neurochemistry. 127, 2, p. 233-244 12 p.

Research output: Contribution to journalArticle

Microglia
Interleukin-1
Nitric Oxide Synthase Type II
Chemical activation
Chemokines
11 Citations (Scopus)

Japanese encephalitis virus infection alters both neuronal and astrocytic differentiation of neural stem/progenitor cells

Ariff, I. M., Thounaojam, M. C., Das, S. & Basu, A., Jun 1 2013, In : Journal of Neuroimmune Pharmacology. 8, 3, p. 664-676 13 p.

Research output: Contribution to journalArticle

Japanese Encephalitis Virus
Neural Stem Cells
Stem Cells
Infection
Astrocytes
37 Citations (Scopus)

MicroRNAs in the brain: It's regulatory role in neuroinflammation

Thounaojam, M. C., Kaushik, D. K. & Basu, A., Jan 1 2013, In : Molecular Neurobiology. 47, 3, p. 1034-1044 11 p.

Research output: Contribution to journalArticle

MicroRNAs
Brain
Heart Neoplasms
Protein Transport
Virus Diseases
2012
3 Citations (Scopus)

Amelioration of carbon tetrachloride induced hepatotoxicity in rats by standardized Feronia limonia. linn leaf extracts

Jain, M., Kapadia, R., Jadeja, R. N., Thounaojam, M. C., Devkar, R. V. & Mishra, S. H., Oct 23 2012, In : EXCLI Journal. 11, p. 250-259 10 p.

Research output: Contribution to journalArticle

Limonia acidissima
Plumbaginaceae
carbon tetrachloride
hepatotoxicity
Carbon Tetrachloride
36 Citations (Scopus)

Anthocyanin-rich red cabbage (Brassica oleracea L.) extract attenuates cardiac and hepatic oxidative stress in rats fed an atherogenic diet

Sankhari, J. M., Thounaojam, M. C., Jadeja, R. N., Devkar, R. V. & Ramachandran, A. V., Jun 1 2012, In : Journal of the Science of Food and Agriculture. 92, 8, p. 1688-1693 6 p.

Research output: Contribution to journalArticle

Atherogenic Diet
Anthocyanins
Brassica
Brassica oleracea
cabbage
5 Citations (Scopus)
Clerodendrum
Atherogenic Diet
P-Selectin
Vascular Cell Adhesion Molecule-1
Macrophages
75 Citations (Scopus)

Cytotoxicity evaluation and antimicrobial studies of starch capped water soluble copper nanoparticles

Valodkar, M., Rathore, P. S., Jadeja, R. N., Thounaojam, M., Devkar, R. V. & Thakore, S., Jan 30 2012, In : Journal of Hazardous Materials. 201-202, p. 244-249 6 p.

Research output: Contribution to journalArticle

Cytotoxicity
Starch
starch
Nanoparticles
Copper
1 Citation (Scopus)
Syzygium
Seeds
Oxidative Stress
Cholesterol
Diet
6 Citations (Scopus)

Hepatoprotective activity of Feronia limonia root

Jain, M., Kapadia, R., Jadeja, R. N., Thounaojam, M. C., Devkar, R. V. & Mishra, S. H., Jun 1 2012, In : Journal of Pharmacy and Pharmacology. 64, 6, p. 888-896 9 p.

Research output: Contribution to journalArticle

Plumbaginaceae
Liver
Aspartic Acid
Alanine
Lipid Peroxidation
18 Citations (Scopus)

Hepatoprotective potential of Tecomella undulata stem bark is partially due to the presence of betulinic acid

Jain, M., Kapadia, R., Jadeja, R. N., Thounaojam, M. C., Devkar, R. V. & Mishra, S. H., Aug 30 2012, In : Journal of Ethnopharmacology. 143, 1, p. 194-200 7 p.

Research output: Contribution to journalArticle

Liver
Bignoniaceae
Ayurvedic Medicine
Silymarin
Hep G2 Cells
6 Citations (Scopus)

Protective role of standardized Feronia limonia stem bark methanolic extract against carbon tetrachloride induced hepatotoxicity

Jain, M., Kapadia, R., Jadeja, R. N., Thounaojam, M. C., Devkar, R. V. & Mishra, S. H., Nov 26 2012, In : Annals of Hepatology. 11, 6, p. 935-943 9 p.

Research output: Contribution to journalArticle

Plumbaginaceae
Carbon Tetrachloride
Silymarin
Liver
Antioxidants
3 Citations (Scopus)
Foam Cells
Vascular Cell Adhesion Molecule-1
Macrophages
Foams
Rats
17 Citations (Scopus)
High Fat Diet
Fatty Liver
Nutrition
Fatty Acids
Fats
10 Citations (Scopus)

Synthesis, characterization, DNA binding and cytotoxicity studies of moxifloxacinato complexes

Singh, R., Jadeja, R. N., Thounaojam, M. C., Devkar, R. V. & Chakraborty, D., Sep 1 2012, In : Transition Metal Chemistry. 37, 6, p. 541-551 11 p.

Research output: Contribution to journalArticle

Ethidium
Cytotoxicity
Metal complexes
DNA
Coordination Complexes
33 Citations (Scopus)

Synthesis, DNA binding and antiproliferative activity of ternary copper complexes of moxifloxacin and gatifloxacin against lung cancer cells

Singh, R., Jadeja, R. N., Thounaojam, M. C., Patel, T., Devkar, R. V. & Chakraborty, D., Sep 1 2012, In : Inorganic Chemistry Communications. 23, p. 78-84 7 p.

Research output: Contribution to journalArticle

lungs
Copper
DNA
deoxyribonucleic acid
cancer
9 Citations (Scopus)

Traditional uses, phytochemistry and pharmacology of Clerodendron glandulosum Coleb – a review

Jadeja, R. N., Thounaojam, M. C., Singh, T. B., Devkar, R. V. & Ramachandran, A. V., Jan 1 2012, In : Asian Pacific Journal of Tropical Medicine. 5, 1, p. 1-6 6 p.

Research output: Contribution to journalArticle

Clerodendrum
Obesity
Pharmacology
Free Radicals
Atherosclerosis
10 Citations (Scopus)

Traditional uses, phytochemistry and pharmacology of Tecomella undulata- A review

Jain, M., Kapadia, R., Jadeja, R. N., Thounaojam, M. C., Devkar, R. V. & Mishra, S. H., Dec 1 2012, In : Asian Pacific Journal of Tropical Biomedicine. 2, 3 SUPPL.

Research output: Contribution to journalArticle

Pharmacology
Bignoniaceae
Iridoid Glucosides
Research
Fatty Alcohols
2011
22 Citations (Scopus)

Anti-obesity potential of Clerodendron glandulosum.Coleb leaf aqueous extract

Jadeja, R. N., Thounaojam, M. C., Ramani, U. V., Devkar, R. V. & Ramachandran, A. V., May 17 2011, In : Journal of Ethnopharmacology. 135, 2, p. 338-343 6 p.

Research output: Contribution to journalArticle

Clerodendrum
Adipocytes
Obesity
Peroxisome Proliferator-Activated Receptors
Adiposity
65 Citations (Scopus)

Biocompatible synthesis of peptide capped copper nanoparticles and their biological effect on tumor cells

Valodkar, M., Jadeja, R. N., Thounaojam, M. C., Devkar, R. V. & Thakore, S., Jul 15 2011, In : Materials Chemistry and Physics. 128, 1-2, p. 83-89 7 p.

Research output: Contribution to journalArticle

biological effects
Peptides
peptides
Tumors
Copper
23 Citations (Scopus)

Cardioprotective effect of Sida rhomboidea. Roxb extract against isoproterenol induced myocardial necrosis in rats

Thounaojam, M. C., Jadeja, R. N., Ansarullah, Karn, S. S., Shah, J. D., Patel, D. K., Salunke, S. P., Padate, G. S., Devkar, R. V. & Ramachandran, A. V., Jan 1 2011, In : Experimental and Toxicologic Pathology. 63, 4, p. 351-356 6 p.

Research output: Contribution to journalArticle

Isoproterenol
Rats
Necrosis
Plasmas
Adenosine Triphosphatases
16 Citations (Scopus)
Clerodendrum
Macrophages
monocytes
macrophages
apoptosis
36 Citations (Scopus)

Cytotoxicity evaluation and hepatoprotective potential of bioassay guided fractions from Feronia limmonia Linn leaf

Jain, M., Kapadia, R., Jadeja, R. N., Thounaojam, M. C., Devkar, R. V. & Mishra, S. H., Dec 2011, In : Asian Pacific Journal of Tropical Biomedicine. 1, 6, p. 443-447 5 p.

Research output: Contribution to journalArticle

Plumbaginaceae
Bioassay
Cytotoxicity
Biological Assay
Aspartate Aminotransferases
55 Citations (Scopus)
Latex
latex
Latexes
Nanoparticles
nanoparticles
15 Citations (Scopus)
Macrophages
LDL Lipoproteins
Apoptosis
Oxidation
Copper
38 Citations (Scopus)

In vitro toxicity study of plant latex capped silver nanoparticles in human lung carcinoma cells

Valodkar, M., Jadeja, R. N., Thounaojam, M. C., Devkar, R. V. & Thakore, S., Dec 1 2011, In : Materials Science and Engineering C. 31, 8, p. 1723-1728 6 p.

Research output: Contribution to journalArticle

Latex
latex
Latexes
Silver
toxicity
20 Citations (Scopus)

Oxidative stress induced apoptosis of human lung carcinoma (A549) cells by a novel copper nanorod formulation

Thounaojam, M. C., Jadeja, R. N., Valodkar, M., Nagar, P. S., Devkar, R. V. & Thakore, S., Nov 1 2011, In : Food and Chemical Toxicology. 49, 11, p. 2990-2996 7 p.

Research output: Contribution to journalArticle

nanorods
Nanotubes
Oxidative stress
Nanorods
carcinoma
13 Citations (Scopus)

Safety Evaluations on Ethanolic Extract of Red Cabbage (Brassica oleracea L.) in Mice

Thounaojam, M. C., Jadeja, R. N., Sankhari, J. M., Devkar, R. V. & Ramachandran, A. V., Jan 1 2011, In : Journal of Food Science. 76, 1

Research output: Contribution to journalArticle

Brassica
Brassica oleracea
cabbage
Body Weight
Safety
10 Citations (Scopus)
obesity
diets
fats
High Fat Diet
food intake
22 Citations (Scopus)

Toxicological evaluation and hepatoprotective potential of Clerodendron glandulosum.Coleb leaf extract

Jadeja, R. N., Thounaojam, M. C., Ansarullah, Jadav, S. V., Patel, M. D., Patel, D. K., Salunke, S. P., Padate, G. S., Devkar, R. V. & Ramachandran, A. V., Jan 1 2011, In : Human and Experimental Toxicology. 30, 1, p. 63-70 8 p.

Research output: Contribution to journalArticle

Clerodendrum
Liver
Toxicology
Toxicity
Silymarin
2010
9 Citations (Scopus)

Actividades antioxidante y neutralizante de radicales libres del extracto metanólico de sida rhomboidea. Roxb determinadas por diferentes modelos in vitro

Translated title of the contribution: Antioxidant and free radical scavenging activity of sida rhomboidea. Roxb methanolic extract determined using different in vitro modelsThounaojam, M. C., Jadeja, R. N., Devkar, R. V. & Ramachandran, A. V., May 1 2010, In : Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas. 9, 3, p. 191-198 8 p.

Research output: Contribution to journalArticle

Sida
Inhibitory Concentration 50
Free Radicals
inhibitory concentration 50
Antioxidants
7 Citations (Scopus)

Acute and sub chronic oral toxicity of Sida rhomboidea. Roxb Leaf Extract

Thounaojam, M. C., Jadeja, R. N., Patel, D. K., Devkar, R. V. & Ramachandran, A. V., Mar 11 2010, In : Journal of Complementary and Integrative Medicine. 7, 1, 1.

Research output: Contribution to journalArticle

Body Weight
Poisons
Weight Gain
Oral Administration
Eating
21 Citations (Scopus)

Clerodendron glandulosum.Coleb extract ameliorates high fat diet/fatty acid induced lipotoxicity in experimental models of non-alcoholic steatohepatitis

Jadeja, R. N., Thounaojam, M. C., Dandekar, D. S., Devkar, R. V. & Ramachandran, A. V., Dec 1 2010, In : Food and Chemical Toxicology. 48, 12, p. 3424-3431 8 p.

Research output: Contribution to journalArticle

Clerodendrum
High Fat Diet
Fatty Liver
high fat diet
Nutrition