Modesto Antonio Rojas

Assistant Research Scientist

  • 683 Citations
  • 15 h-Index
20062018

Research output per year

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Research Output

  • 683 Citations
  • 15 h-Index
  • 19 Article
  • 1 Review article
2018

Blockade of TREM-1 prevents vitreoretinal neovascularization in mice with oxygen-induced retinopathy

Rojas, M. A., Shen, Z. T., Caldwell, R. B. & Sigalov, A. B., Sep 2018, In : Biochimica et Biophysica Acta - Molecular Basis of Disease. 1864, 9, p. 2761-2768 8 p.

Research output: Contribution to journalArticle

2 Scopus citations

Mechanisms of diabetes-induced endothelial cell senescence: Role of arginase 1

Shosha, E., Xu, Z., Priya Narayanan, S., Lemtalsi, T., Fouda, A. Y., Rojas, M., Xing, J., Fulton, D., William Caldwell, R. & Caldwell, R. B., Apr 17 2018, In : International journal of molecular sciences. 19, 4, 1215.

Research output: Contribution to journalArticle

5 Scopus citations

Neurofibromin deficiency induces endothelial cell proliferation and retinal neovascularization

Zhang, H., Hudson, F. Z., Xu, Z., Tritz, R., Rojas, M., Patel, C., Haigh, S. B., Bordán, Z., Ingram, D. A., Fulton, D. J., Weintraub, N. L., Caldwell, R. B. & Stansfield, B. K., May 2018, In : Investigative Ophthalmology and Visual Science. 59, 6, p. 2520-2528 9 p.

Research output: Contribution to journalArticle

2 Scopus citations
2016

Arginase 2 promotes neurovascular degeneration during ischemia/reperfusion injury

Shosha, E., Xu, Z., Yokota, H., Saul, A., Rojas, M., William Caldwell, R., Caldwell, R. B. & Priya Narayanan, S., Jan 1 2016, In : Cell Death and Disease. 7, 11, e2483.

Research output: Contribution to journalArticle

18 Scopus citations
2015

Arginase inhibition enhances angiogenesis in endothelial cells exposed to hypoxia

Wang, L., Bhatta, A., Flores Toque, H. A., Rojas, M. A., Yao, L., Xu, Z., Patel, C., Caldwell, R. B. & Caldwell, R. W., Mar 1 2015, In : Microvascular Research. 98, p. 1-8 8 p.

Research output: Contribution to journalArticle

11 Scopus citations
2014

Anti-angiogenic actions of the mangosteen polyphenolic xanthone derivative α-mangostin

Jittiporn, K., Suwanpradid, J., Patel, C., Rojas, M., Thirawarapan, S., Moongkarndi, P., Suvitayavat, W. & Caldwell, R. B., May 2014, In : Microvascular Research. 93, p. 72-79 8 p.

Research output: Contribution to journalArticle

21 Scopus citations

Arginase 2 deficiency prevents oxidative stress and limits hyperoxia-induced retinal vascular degeneration

Suwanpradid, J., Rojas, M., Behzadian, M. A., Caldwell, R. W. & Caldwell, R. B., Nov 6 2014, In : PloS one. 9, 11, 110604.

Research output: Contribution to journalArticle

20 Scopus citations
2013

Arginase 1 mediates increased blood pressure and contributes to vascular endothelial dysfunction in deoxycorticosterone acetate-salt hypertension

Toque, H. A., Nunes, K. P., Rojas, M., Bhatta, A., Yao, L., Xu, Z., Romero, M. J., Webb, R. C., Caldwell, R. B. & Caldwell, R. W., Sep 16 2013, In : Frontiers in immunology. 4, JUL, Article 219.

Research output: Contribution to journalArticle

29 Scopus citations

Arginase as a mediator of diabetic retinopathy

Patel, C., Rojas, M., Narayanan, S. P., Zhang, W., Xu, Z., Lemtalsi, T., Jittiporn, K., Caldwell, R. W. & Caldwell, R. B., Sep 16 2013, In : Frontiers in immunology. 4, JUL, Article 173.

Research output: Contribution to journalArticle

26 Scopus citations

Arginase in retinopathy

Narayanan, S. P., Rojas, M., Suwanpradid, J., Toque, H. A., Caldwell, R. W. & Caldwell, R. B., Sep 1 2013, In : Progress in Retinal and Eye Research. 36, p. 260-280 21 p.

Research output: Contribution to journalArticle

41 Scopus citations

Prevention of diabetes-induced arginase activation and vascular dysfunction by Rho kinase (ROCK) knockout

Yao, L., Chandra, S., Toque, H. A., Bhatta, A., Rojas, M., Caldwell, R. B. & Caldwell, R. W., Mar 1 2013, In : Cardiovascular Research. 97, 3, p. 509-519 11 p.

Research output: Contribution to journalArticle

61 Scopus citations

Requirement of NOX2 expression in both retina and bone marrow for diabetes-induced retinal vascular injury

Rojas, M., Zhang, W., Xu, Z., Lemtalsi, T., Chandler, P., Toque, H. A., Caldwell, R. W. & Caldwell, R. B., Dec 17 2013, In : PloS one. 8, 12, e84357.

Research output: Contribution to journalArticle

27 Scopus citations

The role of arginase i in diabetes-induced retinal vascular dysfunction in mouse and rat models of diabetes

Elms, S. C., Toque, H. A., Rojas, M., Xu, Z., Caldwell, R. W. & Caldwell, R. B., Mar 1 2013, In : Diabetologia. 56, 3, p. 654-662 9 p.

Research output: Contribution to journalArticle

36 Scopus citations
2011

Anti-inflammatory therapy for diabetic retinopathy

Zhang, W., Liu, H., Rojas, M. A., Caldwell, R. W. & Caldwell, R. B., May 1 2011, In : Immunotherapy. 3, 5, p. 609-628 20 p.

Research output: Contribution to journalReview article

68 Scopus citations

Neuroprotection from retinal ischemia/reperfusion injury by NOX2 NADPH oxidase deletion

Yokota, H., Narayanan, S. P., Zhang, W., Liu, H., Rojas, M., Xu, Z., Lemtalsi, T., Nagaoka, T., Yoshida, A., Brooks, S. E., Caldwell, R. W. & Caldwell, R. B., Oct 1 2011, In : Investigative Ophthalmology and Visual Science. 52, 11, p. 8123-8131 9 p.

Research output: Contribution to journalArticle

51 Scopus citations
2010

Role of IL-6 in angiotensin II-induced retinal vascular inflammation

Rojas, M., Zhang, W., Lee, D. L., Romero, M. J., Nguyen, D. T., Al-Shabrawey, M., Tsai, N. T., Liou, G. I., Brands, M. W., Caldwell, R. W. & Caldwell, R. B., Mar 1 2010, In : Investigative Ophthalmology and Visual Science. 51, 3, p. 1709-1718 10 p.

Research output: Contribution to journalArticle

45 Scopus citations
2009

Arginase activity mediates retinal inflammation in endotoxin-induced uveitis

Zhang, W., Baban, B., Rojas, M., Tofigh, S., Virmani, S. K., Patel, C., Behzadian, M. A., Romero, M. J., Caldwell, R. W. & Caldwell, R. B., Aug 2009, In : American Journal of Pathology. 175, 2, p. 891-902 12 p.

Research output: Contribution to journalArticle

47 Scopus citations

NAD(P)H oxidase-dependent regulation of CCL2 production during retinal inflammation

Zhang, W., Rojas, M., Lilly, B., Tsai, N. T., Lemtalsi, T., Liou, G. I., Caldwell, R. W. & Caldwell, R. B., Dec 1 2009, In : Investigative Ophthalmology and Visual Science. 50, 6, p. 3033-3040 8 p.

Research output: Contribution to journalArticle

26 Scopus citations
2008

Role of NADPH oxidase in retinal vascular inflammation

Al-Shabrawey, M., Rojas, M., Sanders, T., Behzadian, A., El-Remessy, A., Bartoli, M., Parpia, A. K., Liou, G. & Caldwell, R. B., Jul 1 2008, In : Investigative Ophthalmology and Visual Science. 49, 7, p. 3239-3244 6 p.

Research output: Contribution to journalArticle

137 Scopus citations
2006

Blood Pressure Early in Diabetes Depends on a Balance Between Glomerular Filtration Rate and the Renin-Angiotensin System

Rojas, M., Bell, T. D., Sturgis, L. S. C., Springfield, V., Janardhanan, R., Fleming, C. & Brands, M. W., Dec 1 2006, In : American journal of hypertension. 19, 12, p. 1249-1255 7 p.

Research output: Contribution to journalArticle

10 Scopus citations