• 4778 Citations
  • 36 h-Index
1980 …2019
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  • 7 Similar Profiles
Epidermal Growth Factor Receptor Medicine & Life Sciences
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Ligands Medicine & Life Sciences
Protein Isoforms Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
erbB-1 Genes Medicine & Life Sciences
Transforming Growth Factor alpha Medicine & Life Sciences

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Projects 1980 2019

TRANSFORMING POTENTIAL OF V AND C-MYC ONCOGENES

Maihle, N. J.

National Institutes of Health

10/23/85 → …

Project: Research projectPostdoctoral Individual National Research Service Award

CANCER CENTER SUPPORT GRANT (COMPREHENSIVE)

Maihle, N. J., Lingle, W., O'Connell, M., Diasio, R. B., Greipp, P., David, C., Held, K., Weiland, L., Moertel, C., Burnham, N., Kovach, J., Wold, L., Katzmann, J., Wieand, H., Jenkins, R., Ames, M., Cunningham, J., Wettstein, P. J., Raghavakaimal, S., Buckner, J., Adjei, A., Kocher, J., Highsmith, W. E., Beebe, T., Vile, R., Okuno, S., Federspiel, M., Sarkaria, J., Pitot, H., Salisbury, J., van Deursen, J., Alberts, S., Sargent, D., Roche, P., Thibodeau, S. N., Ingle, J. N., Reid, J., Colon-Otero, G., Galanis, E., Weinshilboum, R., Ames, M., Dewald, G., Liebson, P., Banks, P., Prendergast, F., Wiebeu, E., Clapham, D., Spelsburg, T., Grendahl, D., McCormick, D., Leibson, P., O'Fallon, J., Kline, B., Prendergast, F., Chute, C., McKean, D., Highsmith, E., Kwon, E. D., Wieben, E., Flotte, T., Pitot, H., Leibson, P., Lawson, M., Grendahl, D., McCormick, D. & Jenkins, R. B.

National Institutes of Health

3/1/802/28/19

Project: Research projectCenter Core Grants

Intercellular Signaling Peptides and Proteins
Research
Neoplasms
Radiobiology
Immunogenetics

LIGAND INDEPENDENT ONCOGENIC SIGNALING BY ERBB1

Maihle, N. J.

National Institutes of Health

8/5/995/31/05

Project: Research projectResearch Project

Ligands
Tyrosine
Fibroblasts
Calmodulin-Binding Proteins
Guanine Nucleotide Exchange Factors

IL-6 &SIL-6R GROWTH INHIBITION OF BREAST CARCINOMA

Maihle, N. J.

National Institutes of Health

7/1/964/30/00

Project: Research projectResearch Project

Interleukin-6
Breast Neoplasms
Epithelial Cells
Growth
Breast
Proto-Oncogenes
Ovarian Neoplasms
Serum
Neoplasms
Breast Neoplasms

Research Output 1980 2018

1 Citations

Synergistic Targeting HER2 and EGFR with Bivalent Aptamer-siRNA Chimera Efficiently Inhibits HER2-Positive Tumor Growth

Xue, L., Maihle, N. J., Yu, X., Tang, S. C. & Liu, H., Nov 5 2018, In : Molecular Pharmaceutics. 15, 11, p. 4801-4813 13 p.

Research output: Contribution to journalArticle

Small Interfering RNA
Breast Neoplasms
Growth
Drug Resistance
Pharmaceutical Preparations
4 Citations

Targeting EGFR/HER2/HER3 with a Three-in-One Aptamer-siRNA Chimera Confers Superior Activity against HER2+ Breast Cancer

Yu, X., Ghamande, S. A., Liu, H., Xue, L., Zhao, S., Tan, W., Zhao, L., Tang, S. C., Wu, D., Korkaya, H., Maihle, N. J. & Liu, H., Mar 2 2018, In : Molecular Therapy - Nucleic Acids. 10, p. 317-330 14 p.

Research output: Contribution to journalArticle

Small Interfering RNA
Breast Neoplasms
Nucleotide Aptamers
Antibodies
Heterografts

Anti-HER-2 therapy following severe trastuzumab-induced cardiac toxicity

Sadek, I., Keaton, M., Maihle, N. J. & Tang, S. C., Sep 1 2017, In : Genes and Diseases. 4, 3, p. 159-162 4 p.

Research output: Contribution to journalArticle

Toxicity
Thoracic Wall
Breast Neoplasms
Therapeutics
Disease control
1 Citations

Enhancing diversity in the hematology biomedical research workforce: A mentoring program to improve the odds of career success for early stage investigators

Pace, B. S., Makala, L. H., Sarkar, R., Liu, L., Takezaki, M., Mohandas, N., Dixon, G., Werner, E. M., Jeffe, D. B., Rice, T. K., Maihle, N. J. & González, J., Dec 1 2017, In : American Journal of Hematology. 92, 12, p. 1275-1279 5 p.

Research output: Contribution to journalComment/debate

4 Citations

Malignant pericytes expressing GT198 give rise to tumor cells through angiogenesis

Zhang, L., Wang, Y., Rashid, M. H., Liu, M., Angara, K., Mivechi, N. F., Maihle, N. J., Arbab, A. S. & Ko, L., Feb 7 2017, In : Oncotarget. 8, 31, p. 51591-51607 17 p.

Research output: Contribution to journalArticle

Pericytes
Neoplasms
Heterografts
Mouth Neoplasms
Oncogene Proteins