• 4930 Citations
  • 27 h-Index
1980 …2019

Research output per year

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Research Output

  • 4930 Citations
  • 27 h-Index
  • 49 Article
  • 4 Review article
  • 1 Editorial
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Article
2019

Disruption of Immune Homeostasis in Human Dendritic Cells via Regulation of Autophagy and Apoptosis by Porphyromonas gingivalis

Meghil, M. M., Tawfik, O. K., Elashiry, M., Rajendran, M., Arce, R. M., Fulton, D. J., Schoenlein, P. V. & Cutler, C. W., Sep 24 2019, In : Frontiers in immunology. 10, 2286.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
2016

Ceramide activates lysosomal cathepsin B and cathepsin D to attenuate autophagy and induces ER stress to suppress myeloidderived suppressor cells

Liu, F., Li, X., Lu, C., Bai, A., Bielawski, J., Bielawska, A., Marshall, B., Schoenlein, P. V., Lebedyeva, I. O. & Liu, K., Jan 1 2016, In : Oncotarget. 7, 51, p. 83907-83925 19 p.

Research output: Contribution to journalArticle

31 Scopus citations
2015

Porphyromonas gingivalis Evasion of Autophagy and Intracellular Killing by Human Myeloid Dendritic Cells Involves DC-SIGN-TLR2 Crosstalk

El-Awady, A. R., Miles, B., Scisci, E., Kurago, Z. B., Palani, C. D., Arce, R. M., Waller, J. L., Genco, C. A., Slocum, C., Manning, M., Schoenlein, P. V. & Cutler, C. W., Jan 1 2015, In : PLoS Pathogens. 11, 2, e1004647.

Research output: Contribution to journalArticle

37 Scopus citations
2014

Rapamycin up-regulation of autophagy reduces infarct size and improves outcomes in both permanent MCAL, and embolic MCAO, murine models of stroke

Buckley, K. M., Hess, D. L., Sazonova, I. Y., Periyasamy-Thandavan, S., Barrett, J. R., Kirks, R., Grace, H., Kondrikova, G., Johnson, M. H., Hess, D. C., Schoenlein, P. V., Hoda, M. N. & Hill, W. D., Jun 21 2014, In : Experimental and Translational Stroke Medicine. 6, 1, 8.

Research output: Contribution to journalArticle

51 Scopus citations
2013

Molecular mechanism of SLC5A8 inactivation in breast cancer

Elangovan, S., Pathania, R., Ramachandran, S., Ananth, S., Padia, R. N., Srinivas, S. R., Babu, E., Hawthorn, L., Schoenlein, P. V., Boettger, T., Smith, S. B., Prasad, P. D., Ganapathy, V. & Thangaraju, M., Nov 6 2013, In : Molecular and Cellular Biology. 33, 19, p. 3920-3935 16 p.

Research output: Contribution to journalArticle

20 Scopus citations
2012

Insulin-like growth factor 1 attenuates antiestrogen- and antiprogestin-induced apoptosis in ER + breast cancer cells by MEK1 regulation of the BH3-only pro-apoptotic protein Bim

Periyasamy-Thandavan, S., Takhar, S., Singer, A., Dohn, M. R., Jackson, W. H., Welborn, A. E., LeRoith, D., Marrero, M., Thangaraju, M., Huang, S. & Schoenlein, P. V., Mar 19 2012, In : Breast Cancer Research. 14, 2, R52.

Research output: Contribution to journalArticle

15 Scopus citations
2011

SIRT1 is essential for oncogenic signaling by estrogen/ estrogen receptor α in breast cancer

Elangovan, S., Ramachandran, S., Venkatesan, N., Ananth, S., Gnana-Prakasam, J. P., Martin, P. M., Browning, D. D., Schoenlein, P. V., Prasad, P. D., Ganapathy, V. & Thangaraju, M., Nov 1 2011, In : Cancer Research. 71, 21, p. 6654-6664 11 p.

Research output: Contribution to journalArticle

80 Scopus citations

SLC6A14 (ATB 0,+) protein, a highly concentrative and broad specific amino acid transporter, is a novel and effective drug target for treatment of estrogen receptor-positive breast cancer

Karunakaran, S., Ramachandran, S., Coothankandaswamy, V., Elangovan, S., Babu, E., Periyasamy-Thandavan, S., Gurav, A., Gnanaprakasam, J. P., Singh, N., Schoenlein, P. V., Prasad, P. D., Thangaraju, M. & Ganapathy, V., Sep 9 2011, In : Journal of Biological Chemistry. 286, 36, p. 31830-31838 9 p.

Research output: Contribution to journalArticle

79 Scopus citations
2010

Bortezomib blocks the catabolic process of autophagy via a cathepsin-dependent mechanism, affects endoplasmic reticulum stress and induces caspase-dependent cell death in antiestrogen-sensitive and resistant ER + breast cancer cells

Periyasamy-Thandavan, S., Jackson, W. H., Samaddar, J. S., Erickson, B., Barrett, J. R., Raney, L., Gopal, E., Ganapathy, V., Hill, W. D., Bhalla, K. N. & Schoenlein, P. V., Jan 1 2010, In : Autophagy. 6, 1, p. 19-35 17 p.

Research output: Contribution to journalArticle

42 Scopus citations
2009

Autophagy facilitates the progression of ERα-positive breast cancer cells to antiestrogen resistance

Schoenlein, P. V., Periyasamy-Thandavan, S., Samaddar, J. S., Jackson, W. H. & Barrett, J. T., Apr 1 2009, In : Autophagy. 5, 3, p. 400-403 4 p.

Research output: Contribution to journalArticle

107 Scopus citations

IFN regulatory factor 8 sensitizes soft tissue sarcoma cells to death receptor-initiated apoptosis via repression of FLICE-like protein expression

Yang, D., Wang, S., Brooks, C., Dong, Z., Schoenlein, P. V., Kumar, V., Ouyang, X., Xiong, H., Lahat, G., Hayes-Jordan, A., Lazar, A., Pollock, R., Lev, D. & Liu, K., Feb 1 2009, In : Cancer Research. 69, 3, p. 1080-1088 9 p.

Research output: Contribution to journalArticle

26 Scopus citations
2008

A role for macroautophagy in protection against 4-hydroxytamoxifen-induced cell death and the development of antiestrogen resistance

Samaddar, J. S., Gaddy, V. T., Duplantier, J., Thandavan, S. P., Shah, M., Smith, M. J., Browning, D., Rawson, J., Smith, S. B., Barrett, J. T. & Schoenlein, P. V., Oct 22 2008, In : Molecular cancer therapeutics. 7, 9, p. 2977-2987 11 p.

Research output: Contribution to journalArticle

127 Scopus citations

Expression of cyclic guanosine monophosphate-dependent protein kinase in metastatic colon carcinoma cells blocks tumor angiogenesis

Kwon, I. K., Schoenlein, P. V., Delk, J., Liu, K., Thangaraju, M., Dulin, N. O., Ganapathy, V., Berger, F. G. & Browning, D. D., Apr 1 2008, In : Cancer. 112, 7, p. 1462-1470 9 p.

Research output: Contribution to journalArticle

23 Scopus citations
2007
14 Scopus citations

Repression of IFN regulatory factor 8 by DNA methylation is a molecular determinant of apoptotic resistance and metastatic phenotype in metastatic tumor cells

Yang, D., Thangaraju, M., Greeneltch, K., Browning, D. D., Schoenlein, P. V., Tamura, T., Ozato, K., Ganapathy, V., Abrams, S. I. & Liu, K., Apr 1 2007, In : Cancer Research. 67, 7, p. 3301-3309 9 p.

Research output: Contribution to journalArticle

67 Scopus citations
2006

An anti-tumor role for cGMP-dependent protein kinase

Hou, Y., Gupta, N., Schoenlein, P., Wong, E., Martindale, R., Ganapathy, V. & Browning, D., Aug 18 2006, In : Cancer Letters. 240, 1, p. 60-68 9 p.

Research output: Contribution to journalArticle

45 Scopus citations

A role for cyclic-GMP dependent protein kinase in anoikis

Hou, Y., Wong, E., Martin, J., Schoenlein, P. V., Dostmann, W. R. & Browning, D. D., Jun 1 2006, In : Cellular Signalling. 18, 6, p. 882-888 7 p.

Research output: Contribution to journalArticle

23 Scopus citations

Caspase-mediated cleavage of ATM during cisplatin-induced tubular cell apoptosis: Inactivation of its kinase activity toward p53

Wang, J., Pabla, N., Wang, C. Y., Wang, W., Schoenlein, P. V. & Dong, Z., Dec 14 2006, In : American Journal of Physiology - Renal Physiology. 291, 6, p. F1300-F1307

Research output: Contribution to journalArticle

38 Scopus citations
2004

Mifepristone induces growth arrest, caspase activation, and apoptosis of estrogen receptor-expressing, antiestrogen-resistant breast cancer cells

Gaddy, V. T., Barrett, J. T., Delk, J. N., Kallab, A. M., Porter, A. G. & Schoenlein, P. V., Aug 1 2004, In : Clinical Cancer Research. 10, 15, p. 5215-5225 11 p.

Research output: Contribution to journalArticle

43 Scopus citations

Protective effects of EGCG on salivary gland cells treated with γ-radiation or cis-platinum(II) diammine dichloride

Yamamoto, T., Staples, J., Wataha, J., Lewis, J., Lockwood, P., Schoenlein, P., Rao, S., Osaki, T., Dickinson, D., Kamatani, T., Schuster, G. & Hsu, S., Sep 1 2004, In : Anticancer research. 24, 5 A, p. 3065-3073 9 p.

Research output: Contribution to journalArticle

35 Scopus citations
2003

Green tea polyphenol targets the mitochondria in tumor cells inducing caspase 3-dependent apoptosis

Hsu, S., Lewis, J., Singh, B., Schoenlein, P. V., Osaki, T., Athar, M., Porter, A. G. & Schuster, G., Mar 1 2003, In : Anticancer Research. 23, 2 B, p. 1533-1539 7 p.

Research output: Contribution to journalArticle

71 Scopus citations
33 Scopus citations
21 Scopus citations
2001

Apoptotic cell death in the mouse retinal ganglion cell layer is induced in vivo by the excitatory amino acid homocysteine

Moore, P., El-sherbeny, A., Roon, P., Schoenlein, P. V., Ganapathy, V. & Smith, S. B., Jan 1 2001, In : Experimental eye research. 73, 1, p. 45-57 13 p.

Research output: Contribution to journalArticle

120 Scopus citations
1999
13 Scopus citations
1998

Additive effect of mifepristone and tamoxifen on apoptotic pathways in MCF-7 human breast cancer cells

El Etreby, M. F., Liang, Y., Wrenn, R. W. & Schoenlein, P. V., Dec 22 1998, In : Breast Cancer Research and Treatment. 51, 2, p. 149-168 20 p.

Research output: Contribution to journalArticle

58 Scopus citations

Efficient transduction of human hematopoietic cells with the human multidrug resistance gene I via SV40 pseudovirions

Rund, D., Dagan, M., Dalyot-Herman, N., Kimchi-Sarfaty, C., Schoenlein, P. V., Gottesman, M. M. & Oppenheim, A., Mar 20 1998, In : Human Gene Therapy. 9, 5, p. 649-657 9 p.

Research output: Contribution to journalArticle

37 Scopus citations

Fractionated ionizing radiation accelerates loss of amplified MDR1 genes harbored by extrachromosomal DNA in tumor cells

Sanchez, A. M., Barrett, J. T. & Schoenlein, P. V., Sep 1 1998, In : Cancer Research. 58, 17, p. 3845-3854 10 p.

Research output: Contribution to journalArticle

21 Scopus citations
1997

Enhanced potency of daunorubicin against multidrug resistant subline KB-Ch(R)-8-5-11 by a pulsed magnetic field

Liang, Y., Hannan, C. J., Chang, B. K. & Schoenlein, P. V., Aug 13 1997, In : Anticancer Research. 17, 3 C, p. 2083-2088 6 p.

Research output: Contribution to journalArticle

22 Scopus citations
1996

MDR1/P-glycoprotein function. I. Effect of hypotonicity and inhibitors on rhodamine 123 exclusion

Weaver, J. L., McKinney, L., Schoenlein, P. V., Goldenberg, S., Gottesman, M. M. & Aszalos, A., May 1 1996, In : American Journal of Physiology - Cell Physiology. 270, 5 39-5, p. C1447-C1452

Research output: Contribution to journalArticle

12 Scopus citations
1995

Acquisition of multiple copies of a mutant topoisomerase IIα allele by chromosome 17 aneuploidy is associated with etoposide resistance in human melanoma cell lines

Campain, J. A., Slovak, M. L., Schoenlein, P. V., Popescu, N. C., Gottesman, M. M. & Pastan, I., Nov 1 1995, In : Somatic Cell and Molecular Genetics. 21, 6, p. 451-471 21 p.

Research output: Contribution to journalArticle

16 Scopus citations

Characterisation of high-level cisplatin-resistant cell lines established from a human hepatoma cell line and human KB adenocarcinoma cells: Cross-resistance and protein changes

Shen, D. W., Akiyama, S. I., Akiyama, S. I., Schoenlein, P. V. & Gottesman, M. M., Apr 1995, In : British Journal of Cancer. 71, 4, p. 676-683 8 p.

Research output: Contribution to journalArticle

72 Scopus citations
1994

Putative “MDR enhancer” is located on human chromosome 20 and not linked to the MDRI gene on chromosome 7

Germann, U. A., Schoenlein, P. V., Zimonjic, D. B., Popescu, N. C., Pastan, I. & Gottesman, M. M., Aug 1994, In : Genes, Chromosomes and Cancer. 10, 4, p. 267-274 8 p.

Research output: Contribution to journalArticle

6 Scopus citations
1993

A histidine protein kinase is involved in polar organelle development in Caulobacter crescentus

Shui Ping Wang, P. W., Sharma, P. L., Schoenlein, P. V. & Ely, B., Jan 28 1993, In : Proceedings of the National Academy of Sciences of the United States of America. 90, 2, p. 630-634 5 p.

Research output: Contribution to journalArticle

100 Scopus citations

Molecular cytogenetics of multiple drug resistance

Schoenlein, P. V., Feb 1 1993, In : Cytotechnology. 12, 1-3, p. 63-89 27 p.

Research output: Contribution to journalArticle

25 Scopus citations
1992
56 Scopus citations

The Caulobacter crescentus flaFG region regulates synthesis and assembly of flagellin proteins encoded by two genetically unlinked gene clusters

Schoenlein, P. V., Lui, J., Gallman, L. & Ely, B., Jan 1 1992, In : Journal of Bacteriology. 174, 19, p. 6046-6053 8 p.

Research output: Contribution to journalArticle

11 Scopus citations

Transplantation of bone marrow cells from transgenic mice expressing the human MDR1 gene results in long-term protection against the myelosuppressive effect of chemotherapy in mice

Mickisch, G. H., Aksentijevich, I., Schoenlein, P. V., Goldstein, L. J., Galski, H., Stahle, C., Sachs, D. H., Pastan, I. & Gottesman, M. M., Jan 1 1992, In : Blood. 79, 4, p. 1087-1093 7 p.

Research output: Contribution to journalArticle

Open Access
88 Scopus citations
1991

Laser scanning and confocal microscopy of daunorubicin, doxorubicin, and rhodamine 123 in multidrug-resistant cells

Weaver, J. L., Pine, P. S., Aszalos, A., Schoenlein, P. V., Currier, S. J., Padmanabhan, R. & Gottesman, M. M., Jan 1 1991, In : Experimental Cell Research. 196, 2, p. 323-329 7 p.

Research output: Contribution to journalArticle

94 Scopus citations
1990

A Caulobacter gene involved in polar morphogenesis

Driks, A., Schoenlein, P. V., DeRosier, D. J., Shapiro, L. & Ely, B., Jan 1 1990, In : Journal of Bacteriology. 172, 4, p. 2113-2123 11 p.

Research output: Contribution to journalArticle

9 Scopus citations

Nucleotide sequence of the Caulobacter crescents flaF and flbt genes and analysis of codon usage in organisms with G+C-rich genomes

Schoenlein, P. V., Gallman, L. S., Winkler, M. E. & Ely, B., Sep 1 1990, In : Gene. 93, 1, p. 17-25 9 p.

Research output: Contribution to journalArticle

14 Scopus citations
1989
8 Scopus citations

Divergent transcription of pdxB and homology between the pdxB and serA gene products in Escherichia coli K-12

Schoenlein, P. V., Roa, B. B. & Winkler, M. E., Jan 1 1989, In : Journal of Bacteriology. 171, 11, p. 6084-6092 9 p.

Research output: Contribution to journalArticle

36 Scopus citations

Organization of the flaFG gene cluster and identification of two additional genes involved in flagellum biogenesis in Caulobacter crescentus

Schoenlein, P. V., Gallman, L. S. & Ely, B., Jan 1 1989, In : Journal of Bacteriology. 171, 3, p. 1544-1553 10 p.

Research output: Contribution to journalArticle

13 Scopus citations
1988

Use of transmissible plasmids as cloning vectors in Caulobacter crescentus

Schoenlein, P. V., Gallman, L. M. & Ely, B., Oct 30 1988, In : Gene. 70, 2, p. 321-329 9 p.

Research output: Contribution to journalArticle

6 Scopus citations
1984

Genetic and physical analyses of Caulobacter rescentus trp genes

Winkler, M. E., Schoenlein, P. V., Ross, C. M., Barrett, J. T. & Ely, B., Dec 19 1984, In : Journal of Bacteriology. 160, 1, p. 279-287 9 p.

Research output: Contribution to journalArticle

5 Scopus citations
1983

Plasmids and bacteriocins in Caulobacter species

Schoenlein, P. V. & Ely, B., Jan 1 1983, In : Journal of Bacteriology. 153, 2, p. 1092-1094 3 p.

Research output: Contribution to journalArticle

1 Scopus citations
1982

Genetic mapping with Tn5-derived auxotrophs of Caulobacter crescentus

Barrett, J. T., Croft, R. H., Ferber, D. M., Gerardot, C. J., Schoenlein, P. V. & Ely, B., Nov 29 1982, In : Journal of Bacteriology. 151, 2, p. 888-898 11 p.

Research output: Contribution to journalArticle

9 Scopus citations
1980

Plasmid-mediated antibiotic resistance in a changing hospital environment: Efficacy of control measures

Bryan, C. S., Parker, E., Schoenlein, P. V., Northey, J., Ely, B. & John, J. F., Jan 1 1980, In : American Journal of Infection Control. 8, 3, p. 65-71 7 p.

Research output: Contribution to journalArticle

6 Scopus citations