• 2927 Citations
  • 29 h-Index
19982019
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Research Output 1998 2019

  • 2927 Citations
  • 29 h-Index
  • 44 Article
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Article
1998
Genes
Cell death
Bearings (structural)
Polypeptides
Assays
1999
52 Citations (Scopus)

A point mutation in the ethylene-inducing xylanase elicitor inhibits the β-1-4-endoxylanase activity but not the elicitation activity

Furman-Matarasso, N., Cohen, E., Du, Q., Chejanovsky, N., Hanania, U. & Avni, A., Oct 1 1999, In : Plant Physiology. 121, 2, p. 345-351 7 p.

Research output: Contribution to journalArticle

endo-1,4-beta-xylanase
Endo-1,4-beta Xylanases
xylanases
point mutation
Point Mutation

Expression of the mutant green fluorescent protein gene in insect cells and larvaae

Pei, Z. F., Du, Q., Qi, Y. P. & Zhu, Y., Dec 1 1999, In : Wuhan Daxue Xuebao/Journal of Wuhan University. 45, 2, p. 231-232 2 p.

Research output: Contribution to journalArticle

Genes
Proteins
Bearings (structural)
Fluorescence
Epidemiology
76 Citations (Scopus)

Isolation of an apoptosis suppressor gene of the Spodoptera littoralis nucleopolyhedrovirus

Du, Q., Lehavi, D., Faktor, O., Qi, Y. & Chejanovsky, N., Jan 23 1999, In : Journal of Virology. 73, 2, p. 1278-1285 8 p.

Research output: Contribution to journalArticle

Spodoptera littoralis nucleopolyhedrovirus
suppressor genes
Suppressor Genes
Nucleopolyhedrovirus
Spodoptera
2000
291 Citations (Scopus)

Regulation of neuregulin signaling by PSD-95 interacting with ErbB4 at CNS synapses

Huang, Y. Z., Won, S., Ali, D. W., Wang, Q., Tanowitz, M., Du, Q., Pelkey, K. A., Yang, D. J., Xiong, W., Salter, M. W. & Mei, L., Jan 1 2000, In : Neuron. 26, 2, p. 443-455 13 p.

Research output: Contribution to journalArticle

Neuregulins
Post-Synaptic Density
Synapses
Phosphotransferases
Hippocampal CA1 Region
2001
202 Citations (Scopus)

A mammalian partner of inscuteable binds NuMA and regulates mitotic spindle organization

Du, Q., Stukenberg, P. T. & Macara, I. G., Dec 22 2001, In : Nature Cell Biology. 3, 12, p. 1069-1075 7 p.

Research output: Contribution to journalArticle

Spindle Poles
Spindle Apparatus
Chromosome Segregation
Mitosis
Ovum
61 Citations (Scopus)

Inhibition of PYK2-induced actin cytoskeleton reorganization, PYK2 autophosphorylation and focal adhesion targeting by FAK

Du, Q., Ren, X. R., Xie, Y., Wang, Q., Mei, L. & Xiong, W., Sep 17 2001, In : Journal of Cell Science. 114, 16, p. 2977-2987 11 p.

Research output: Contribution to journalArticle

Focal Adhesion Kinase 2
Focal Adhesion Protein-Tyrosine Kinases
Focal Adhesions
Actin Cytoskeleton
Protein-Tyrosine Kinases
89 Citations (Scopus)

Regulation of CDC42 GTPase by proline-rich tyrosine kinase 2 interacting with PSGAP, a novel pleckstrin homology and Src homology 3 domain containing rhoGAP protein

Ren, X. R., Du, Q., Huang, Y. Z., Ao, S. Z., Mei, L. & Xiong, W., Mar 5 2001, In : Journal of Cell Biology. 152, 5, p. 971-983 13 p.

Research output: Contribution to journalArticle

Focal Adhesion Kinase 2
src Homology Domains
GTP Phosphohydrolases
Focal Adhesion Protein-Tyrosine Kinases
Proteins
2002
103 Citations (Scopus)

LGN blocks the ability of NuMA to bind and stabilize microtubules: A mechanism for mitotic spindle assembly regulation

Du, Q., Taylor, L., Compton, D. A. & Macara, I. G., Nov 19 2002, In : Current Biology. 12, 22, p. 1928-1933 6 p.

Research output: Contribution to journalArticle

mitotic spindle apparatus
Spindle Apparatus
Microtubules
microtubules
Cells
2003
19 Citations (Scopus)
Immediate-Early Proteins
Autographa californica multiple nucleopolyhedrovirus
Nucleopolyhedrovirus
Spodoptera
Spodoptera littoralis
88 Citations (Scopus)

Regulation of the formation of osteoclastic actin rings by proline-rich tyrosine kinase 2 interacting with gelsolin

Wang, Q., Xie, Y., Du, Q., Wu, X. J., Feng, X., Mei, L., McDonald, J. M. & Xiong, W., Feb 17 2003, In : Journal of Cell Biology. 160, 4, p. 565-575 11 p.

Research output: Contribution to journalArticle

Focal Adhesion Kinase 2
Gelsolin
Actins
Osteoclasts
Cell Adhesion
2004
262 Citations (Scopus)

Mammalian Pins is a conformational switch that links NuMA to heterotrimeric G proteins

Du, Q. & Macara, I. G., Nov 12 2004, In : Cell. 119, 4, p. 503-516 14 p.

Research output: Contribution to journalArticle

Asymmetric Cell Division
Heterotrimeric GTP-Binding Proteins
Cells
Switches
Microtubule Proteins
44 Citations (Scopus)

Multiple mechanisms regulate NuMA dynamics at spindle poles

Kisurina-Evgenieva, O., Mack, G., Du, Q., Macara, I., Khodjakov, A. & Compton, D. A., Dec 15 2004, In : Journal of Cell Science. 117, 26, p. 6391-6400 10 p.

Research output: Contribution to journalArticle

Spindle Poles
Microtubules
Fluorescence Recovery After Photobleaching
Spindle Apparatus
Green Fluorescent Proteins
2005
90 Citations (Scopus)

mPins modulates PSD-95 and SAP102 trafficking and influences NMDA receptor surface expression

Sans, N., Wang, P. Y., Du, Q., Petralia, R. S., Wang, Y. X., Nakka, S., Blumer, J. B., Macara, I. G. & Wenthold, R. J., Dec 1 2005, In : Nature Cell Biology. 7, 12, p. 1079-1090 12 p.

Research output: Contribution to journalArticle

Glutamate Receptors
N-Methyl-D-Aspartate Receptors
Guanylate Kinases
Post-Synaptic Density
Neurons
2006
145 Citations (Scopus)

Regulation of PUMA-α by p53 in cisplatin-induced renal cell apoptosis

Livingston, M. J., Wei, Q., Wang, J., Du, Q., Yu, J., Zhang, L. & Dong, Z., Jul 6 2006, In : Oncogene. 25, 29, p. 4056-4066 11 p.

Research output: Contribution to journalArticle

Cisplatin
Apoptosis
Kidney
Cytochromes c
Mitochondria
218 Citations (Scopus)

The Drosophila NuMA Homolog Mud Regulates Spindle Orientation in Asymmetric Cell Division

Bowman, S. K., Neumüller, R. A., Novatchkova, M., Du, Q. & Knoblich, J. A., Jun 1 2006, In : Developmental Cell. 10, 6, p. 731-742 12 p.

Research output: Contribution to journalArticle

Asymmetric Cell Division
Heterotrimeric GTP-Binding Proteins
Neurology
Spindle Apparatus
Drosophila
2007
57 Citations (Scopus)

DCL4 targets Cucumber mosaic virus satellite RNA at novel secondary structures

Du, Q. S., Duan, C. G., Zhang, Z. H., Fang, Y. Y., Fang, R. X., Xie, Q. & Guo, H. S., Sep 1 2007, In : Journal of Virology. 81, 17, p. 9142-9151 10 p.

Research output: Contribution to journalArticle

Cucumber Mosaic Virus Satellite
Satellite RNAs
satellite RNA
Cucumber mosaic virus
Viral RNA
102 Citations (Scopus)

Myosin X regulates netrin receptors and functions in axonal path-finding

Zhu, X. J., Wang, C. Z., Dai, P. G., Xie, Y., Song, N. N., Liu, Y., Du, Q., Mei, L., Ding, Y. Q. & Xiong, W., Feb 1 2007, In : Nature Cell Biology. 9, 2, p. 184-192 9 p.

Research output: Contribution to journalArticle

Myosins
Colorectal Neoplasms
Neurites
Axons
netrin receptors
2008
33 Citations (Scopus)

A point mutation to Gαi selectively blocks GoLoco motif binding: Direct evidence for Gα·GoLoco complexes in mitotic spindle dynamics

Willard, F. S., Zheng, Z., Guo, J., Digby, G. J., Kimple, A. J., Conley, J. M., Johnston, C. A., Bosch, D., Willard, M. D., Watts, V. J., Lambert, N. A., Ikeda, S. R., Du, Q. & Siderovski, D. P., Dec 26 2008, In : Journal of Biological Chemistry. 283, 52, p. 36698-36710 13 p.

Research output: Contribution to journalArticle

Amino Acid Motifs
Spindle Apparatus
Point Mutation
Proteins
Microtubules
2009
67 Citations (Scopus)

Regulation of heterochromatin remodelling and myogenin expression during muscle differentiation by FAK interaction with MBD2

Luo, S. W., Zhang, C., Zhang, B., Kim, C. H., Qiu, Y. Z., Du, Q. S., Mei, L. & Xiong, W. C., Sep 2 2009, In : EMBO Journal. 28, 17, p. 2568-2582 15 p.

Research output: Contribution to journalArticle

Myogenin
Focal Adhesion Protein-Tyrosine Kinases
Heterochromatin
Muscle
Muscles
2010
44 Citations (Scopus)
Adenosine Triphosphate
Apoptosis
Wounds and Injuries
Kidney
Mitochondrial Membranes
127 Citations (Scopus)

LGN regulates mitotic spindle orientation during epithelial morphogenesis

Zheng, Z., Zhu, H., Wan, Q., Liu, J., Xiao, Z., Siderovski, D. P. & Du, Q., Apr 19 2010, In : Journal of Cell Biology. 189, 2, p. 275-288 14 p.

Research output: Contribution to journalArticle

Spindle Apparatus
Morphogenesis
Madin Darby Canine Kidney Cells
GTP-Binding Proteins
Mitosis
158 Citations (Scopus)

Par3 controls epithelial spindle orientation by aPKC-mediated phosphorylation of apical pins

Hao, Y., Du, Q., Chen, X., Zheng, Z., Balsbaugh, J. L., Maitra, S., Shabanowitz, J., Hunt, D. F. & MacAra, I. G., Oct 26 2010, In : Current Biology. 20, 20, p. 1809-1818 10 p.

Research output: Contribution to journalArticle

Phosphorylation
pins
protein kinase C
phosphorylation
cortex
65 Citations (Scopus)

RNA-dependent RNA polymerase 1 from Nicotiana tabacum suppresses RNA silencing and enhances viral infection in Nicotiana benthamiana

Ying, X. B., Dong, L., Zhu, H., Duan, C. G., Du, Q. S., Lv, D. Q., Fang, Y. Y., Garcia, J. A., Fang, R. X. & Guo, H. S., Apr 1 2010, In : Plant Cell. 22, 4, p. 1358-1372 15 p.

Research output: Contribution to journalArticle

RNA-directed RNA polymerase
RNA Replicase
Nicotiana benthamiana
Virus Diseases
RNA Interference
2011
109 Citations (Scopus)

BSCTV C2 attenuates the degradation of SAMDC1 to suppress DNA methylation-mediated gene silencing in Arabidopsis

Zhang, Z., Chen, H., Huang, X., Xia, R., Zhao, Q., Lai, J., Teng, K., Li, Y., Liang, L., Du, Q., Zhou, X., Guo, H. & Xie, Q., Jan 1 2011, In : Plant Cell. 23, 1, p. 273-288 16 p.

Research output: Contribution to journalArticle

Beet severe curly top virus
Beta vulgaris
Gene Silencing
gene silencing
DNA methylation
69 Citations (Scopus)

LGN/mInsc and LGN/NuMA Complex Structures Suggest Distinct Functions in Asymmetric Cell Division for the Par3/mInsc/LGN and Gαi/LGN/NuMA Pathways

Zhu, J., Wen, W., Zheng, Z., Shang, Y., Wei, Z., Xiao, Z., Pan, Z., Du, Q., Wang, W. & Zhang, M., Aug 5 2011, In : Molecular Cell. 43, 3, p. 418-431 14 p.

Research output: Contribution to journalArticle

Asymmetric Cell Division
Cell Polarity
Spindle Apparatus
Invertebrates
Cell Biology
25 Citations (Scopus)

Satellite RNA-derived small interfering RNA satsiR-12 targeting the 3' untranslated region of Cucumber mosaic virus triggers viral RNAs for degradation

Zhu, H., Duan, C. G., Hou, W. N., Du, Q., Lv, D. Q., Fang, R. X. & Guo, H. S., Dec 1 2011, In : Journal of Virology. 85, 24, p. 13384-13397 14 p.

Research output: Contribution to journalArticle

Satellite RNAs
satellite RNA
Cucumovirus
Cucumber mosaic virus
RNA Stability
2012
13 Citations (Scopus)

Differential regulation of myosin X movements by its cargos, DCC and neogenin

Liu, Y., Peng, Y., Dai, P. G., Du, Q., Mei, L. & Xiong, W., Feb 1 2012, In : Journal of Cell Science. 125, 3, p. 751-762 12 p.

Research output: Contribution to journalArticle

Myosins
Colorectal Neoplasms
Pseudopodia
Actins
Focal Adhesion Protein-Tyrosine Kinases
7 Citations (Scopus)

Galpha/LGN-mediated asymmetric spindle positioning does not lead to unequal cleavage of the mother cell in 3-D cultured MDCK cells

Xiao, Z., Wan, Q., Du, Q. & Zheng, Z., Apr 20 2012, In : Biochemical and Biophysical Research Communications. 420, 4, p. 888-894 7 p.

Research output: Contribution to journalArticle

Ground penetrating radar systems
Heterotrimeric GTP-Binding Proteins
Madin Darby Canine Kidney Cells
Somatostatin-Secreting Cells
Elongation
32 Citations (Scopus)

Regulation of myosin activation during cell-cell contact formation by Par3-Lgl antagonism: Entosis without matrix detachment

Wan, Q., Liu, J., Zheng, Z., Zhu, H., Chu, X., Dong, Z., Huang, S. & Du, Q., Jun 1 2012, In : Molecular Biology of the Cell. 23, 11, p. 2076-2091 16 p.

Research output: Contribution to journalArticle

Entosis
Myosins
Myosin Type II
Cell-in-Cell Formation
Epithelial Cells
2013
32 Citations (Scopus)

Evidence for dynein and astral microtubule-mediated cortical release and transport of Gαi/LGN/NuMA complex in mitotic cells

Zheng, Z., Wan, Q., Liu, J., Zhu, H., Chu, X. & Du, Q., Apr 1 2013, In : Molecular Biology of the Cell. 24, 7, p. 901-913 13 p.

Research output: Contribution to journalArticle

Dyneins
Spindle Apparatus
Microtubules
Cytoplasmic Dyneins
Spindle Poles
17 Citations (Scopus)

Par1b Induces Asymmetric Inheritance of Plasma Membrane Domains via LGN-Dependent Mitotic Spindle Orientation in Proliferating Hepatocytes

Slim, C. L., Lázaro-Diéguez, F., Bijlard, M., Toussaint, M. J. M., de Bruin, A., Du, Q., Müsch, A. & van IJzendoorn, S. C. D., Dec 1 2013, In : PLoS Biology. 11, 12, e1001739.

Research output: Contribution to journalArticle

mitotic spindle apparatus
Spindle Apparatus
Cell membranes
hepatocytes
Hepatocytes
10 Citations (Scopus)

Phosphorylation of NuMA by Aurora-A kinase in PC-3 prostate cancer cells affects proliferation, survival, and interphase NuMA localization

Toughiri, R., Li, X., Du, Q. & Bieberich, C. J., Apr 1 2013, In : Journal of cellular biochemistry. 114, 4, p. 823-830 8 p.

Research output: Contribution to journalArticle

Aurora Kinase A
Phosphorylation
Spindle Apparatus
Interphase
Cell proliferation
2014
31 Citations (Scopus)

Cell cycle-regulated membrane binding of NuMA contributes to efficient anaphase chromosome separation

Zheng, Z., Wan, Q., Meixiong, G. & Du, Q., Mar 1 2014, In : Molecular Biology of the Cell. 25, 5, p. 606-619 14 p.

Research output: Contribution to journalArticle

Anaphase
Spindle Apparatus
Nuclear Envelope
Dyneins
Cell Cycle
5 Citations (Scopus)

Inhibition of pp2a activity confers a trail-sensitive phenotype during malignant transformation

Yang, H., Chen, X., Wang, X., Li, Y., Chen, S., Qian, X., Wang, R., Chen, L., Han, W., Ruan, A., Du, Q., Olumi, A. F. & Zhang, X., Feb 1 2014, In : Molecular Cancer Research. 12, 2, p. 217-227 11 p.

Research output: Contribution to journalArticle

Protein Phosphatase 2
Phenotype
Apoptosis
Polyomavirus Transforming Antigens
Okadaic Acid
90 Citations (Scopus)

MiR-141 Is a key regulator of renal cell carcinoma proliferation and metastasis by controlling EphA2 expression

Chen, X., Wang, X., Ruan, A., Han, W., Zhao, Y., Lu, X., Xiao, P., Shi, H., Wang, R., Chen, L., Chen, S., Du, Q., Yang, H. & Zhang, X., May 15 2014, In : Clinical Cancer Research. 20, 10, p. 2617-2630 14 p.

Research output: Contribution to journalArticle

Renal Cell Carcinoma
varespladib methyl
Cell Proliferation
Neoplasm Metastasis
MicroRNAs
33 Citations (Scopus)

Phosphorylation-dependent interaction between tumor suppressors Dlg and Lgl

Zhu, J., Shang, Y., Wan, Q., Xia, Y., Chen, J., Du, Q. & Zhang, M., Jan 1 2014, In : Cell Research. 24, 4, p. 451-463 13 p.

Research output: Contribution to journalArticle

Larva
Phosphorylation
Guanylate Kinases
Neoplasms
Cell Polarity
30 Citations (Scopus)
Guanylate Kinases
Canidae
Cysts
Epithelium
Kidney
2015
5 Citations (Scopus)

LGN directs interphase endothelial cell behavior via the microtubule network

Wright, C. E., Kushner, E. J., Du, Q. & Bautch, V. L., Sep 23 2015, In : PloS one. 10, 9, e0138763.

Research output: Contribution to journalArticle

Interphase
Endothelial cells
Microtubules
interphase
microtubules
18 Citations (Scopus)

MiR-200c targets CDK2 and suppresses tumorigenesis in renal cell carcinoma

Wang, X., Chen, X., Han, W., Ruan, A., Chen, L., Wang, R., Xu, Z., Xiao, P., Lu, X., Zhao, Y., Zhou, J., Chen, S., Du, Q., Yang, H. & Zhang, X., Dec 2015, In : Molecular Cancer Research. 13, 12, p. 1567-1577 11 p.

Research output: Contribution to journalArticle

Cyclin-Dependent Kinase 2
Renal Cell Carcinoma
Carcinogenesis
MicroRNAs
Growth
2016
4 Citations (Scopus)

Nuclear mitotic apparatus (numa) interacts with and regulates astrin at the mitotic spindle

Chu, X., Chen, X., Wan, Q., Zheng, Z. & Du, Q., Sep 16 2016, In : Journal of Biological Chemistry. 291, 38, p. 20055-20067 13 p.

Research output: Contribution to journalArticle

Spindle Apparatus
Spindle Poles
Poles
Kinetochores
Microtubules
2018
1 Citation (Scopus)

Mir-224/mir-141 ratio as a novel diagnostic biomarker in renal cell carcinoma

Chen, X., Lou, N., Ruan, A., Qiu, B., Yan, Y., Wang, X., Du, Q., Ruan, H., Han, W., Wei, H., Yang, H. & Zhang, X., Aug 2018, In : Oncology Letters. 16, 2, p. 1666-1674 9 p.

Research output: Contribution to journalArticle

Renal Cell Carcinoma
Biomarkers
MicroRNAs
ROC Curve
Sensitivity and Specificity
2019
2 Citations (Scopus)

Par3 is essential for the establishment of planar cell polarity of inner ear hair cells

Malt, A. L., Dailey, Z., Holbrook-Rasmussen, J., Zheng, Y., Hogan, A., Du, Q. & Lu, X., Jan 1 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 11, p. 4999-5008 10 p.

Research output: Contribution to journalArticle

Inner Auditory Hair Cells
Cell Polarity
Inner Ear
Guanine Nucleotide Exchange Factors
Cochlea
1 Citation (Scopus)

Transcription factor TEAD1 is essential for vascular development by promoting vascular smooth muscle differentiation

Wen, T., Liu, J., He, X., Dong, K., Hu, G., Yu, L., Yin, Q., Osman, I., Peng, J., Zheng, Z., Xin, H., Fulton, D. J., Du, Q., Zhang, W. & Zhou, J., Dec 1 2019, In : Cell Death and Differentiation. 26, 12, p. 2790-2806 17 p.

Research output: Contribution to journalArticle

Vascular Smooth Muscle
Smooth Muscle Myocytes
Blood Vessels
Transcription Factors
Cardiac Myocytes