• 4561 Citations
  • 28 h-Index
19962019
If you made any changes in Pure, your changes will be visible here soon.

Research Output 1996 2019

  • 4561 Citations
  • 28 h-Index
  • 40 Article
  • 4 Review article
  • 1 Chapter
1996

Role of nitric oxide in capillary organization and differentiation

Pesai, K. M., Rudic, R. D., García-Cardeña, G., Madri, J. A. & Sessa, W. C., Dec 1 1996, In : FASEB Journal. 10, 3

Research output: Contribution to journalArticle

transforming growth factors
Transforming Growth Factors
nitric oxide
NG-Nitroarginine Methyl Ester
Endothelial cells
1997
108 Citations (Scopus)

Nitric oxide synthase inhibitors attenuate transforming-growth-factor- β1-stimulated capillary organization in vitro

Papapetropoulos, A., Desai, K. M., Rudic, R. D., Mayer, B., Zhang, R., Ruiz-Torres, M. P., García-Cardeña, G., Madri, J. A. & Sessa, W. C., May 17 1997, In : American Journal of Pathology. 150, 5, p. 1835-1844 10 p.

Research output: Contribution to journalArticle

Transforming Growth Factors
Nitric Oxide Synthase
NG-Nitroarginine Methyl Ester
Nitric Oxide
Arginine
1998
636 Citations (Scopus)

Direct evidence for the importance of endothelium-derived nitric oxide in vascular remodeling

Rudic, R. D., Shesely, E. G., Maeda, N., Smithies, O., Segal, S. S. & Sessa, W. C., Feb 15 1998, In : Journal of Clinical Investigation. 101, 4, p. 731-736 6 p.

Research output: Contribution to journalArticle

Nitric Oxide
Nitric Oxide Synthase Type III
External Carotid Artery
Common Carotid Artery
Vascular Endothelium
1999
160 Citations (Scopus)

Molecular control of nitric oxide synthases in the cardiovascular system

Papapetropoulos, A., Rudic, R. D. & Sessa, W. C., Aug 15 1999, In : Cardiovascular Research. 43, 3, p. 509-520 12 p.

Research output: Contribution to journalReview article

Cardiovascular System
Knockout Mice
Nitric Oxide Synthase
Nitric Oxide
Protein Isoforms
82 Citations (Scopus)

Nitric oxide in endothelial dysfunction and vascular remodeling: Clinical correlates and experimental links

Rudic, R. D. & Sessa, W. C., Jan 1 1999, In : American journal of human genetics. 64, 3, p. 673-677 5 p.

Research output: Contribution to journalArticle

Nitric Oxide
Vascular Remodeling
2000
165 Citations (Scopus)

Acute modulation of endothelial Akt/PKB activity alters nitric oxide-dependent vasomotor activity in vivo

Luo, Z., Fujio, Y., Kureishi, Y., Rudic, R. D., Daumerie, G., Fulton, D., Sessa, W. C. & Walsh, K., Aug 2000, In : Journal of Clinical Investigation. 106, 4, p. 493-499 7 p.

Research output: Contribution to journalArticle

Endothelium
Nitric Oxide
Femoral Artery
Nitric Oxide Synthase Type III
Nitroglycerin
413 Citations (Scopus)

In vivo delivery of the caveolin-1 scaffolding domain inhibits nitric oxide synthesis and reduces inflammation

Bucci, M., Gratton, J. P., Rudic, R. D., Acevedo, L., Roviezzo, F., Cirino, G. & Sessa, W. C., Dec 1 2000, In : Nature Medicine. 6, 12, p. 1362-1367 6 p.

Research output: Contribution to journalArticle

Caveolin 1
Nitric Oxide
Inflammation
Caveolae
Signal transduction
52 Citations (Scopus)

Temporal events underlying arterial remodeling after chronic flow reduction in mice: Correlation of structural changes with a deficit in basal nitric oxide synthesis

Rudic, R. D., Bucci, M., Fulton, D., Segal, S. S. & Sessa, W. C., Jun 9 2000, In : Circulation research. 86, 11, p. 1160-1166 7 p.

Research output: Contribution to journalArticle

Ligation
Nitric Oxide
Common Carotid Artery
Nitric Oxide Synthase
External Carotid Artery
2001
20 Citations (Scopus)

Human T cells infiltrate and injure pig coronary artery grafts with activated but not quiescent endothelium in immunodeficient mouse hosts

Tereb, D. A., Kirkiles-Smith, N. C., Kim, R. W., Wang, Y., Rudic, R. D., Schechner, J. S., Lorber, M. I., Bothwell, A. L. M., Pober, J. S. & Tellides, G., Jun 15 2001, In : Transplantation. 71, 11, p. 1622-1630 9 p.

Research output: Contribution to journalArticle

Endothelium
Coronary Vessels
Swine
T-Lymphocytes
Transplants
347 Citations (Scopus)

Regulation of CLOCK and MOP4 by nuclear hormone receptors in the vasculature: A humoral mechanism to reset a peripheral clock

McNamara, P., Seo, S. B., Rudic, R. D., Sehgal, A., Chakravarti, D. & FitzGerald, G. A., Jun 29 2001, In : Cell. 105, 7, p. 877-889 13 p.

Research output: Contribution to journalArticle

Cytoplasmic and Nuclear Receptors
Blood Vessels
Clocks
Hormones
Physiological Phenomena
2002
94 Citations (Scopus)

Functional reconstitution of endothelial nitric oxide synthase reveals the importance of serine 1179 in endothelium-dependent vasomotion

Scotland, R. S., Morales-Ruiz, M., Chen, Y., Yu, J., Rudic, R. D., Fulton, D., Gratton, J. P. & Sessa, W. C., May 3 2002, In : Circulation research. 90, 8, p. 904-910 7 p.

Research output: Contribution to journalArticle

Nitric Oxide Synthase Type III
Serine
Endothelium
Endothelial Cells
Phosphorylation
28 Citations (Scopus)

Nitric oxide-releasing aspirin decreases vascular injury by reducing inflammation and promoting apoptosis

Yu, J., Rudic, R. D. & Sessa, W. C., Jan 1 2002, In : Laboratory Investigation. 82, 7, p. 825-832 8 p.

Research output: Contribution to journalArticle

Vascular System Injuries
Nitric Oxide
Apoptosis
Inflammation
Apolipoproteins E
2004
602 Citations (Scopus)

A functional genomics strategy reveals rora as a component of the mammalian circadian clock

Sato, T. K., Panda, S., Miraglia, L. J., Reyes, T. M., Rudic, R. D., McNamara, P., Naik, K. A., Fitzgerald, G. A., Kay, S. A. & Hogenesch, J. B., Aug 19 2004, In : Neuron. 43, 4, p. 527-537 11 p.

Research output: Contribution to journalArticle

Circadian Clocks
Suprachiasmatic Nucleus
Genomics
Locomotion
Orphan Nuclear Receptors
642 Citations (Scopus)

BMAL1 and CLOCK, two essential components of the circadian clock, are involved in glucose homeostasis

Rudic, R. D., McNamara, P., Curtis, A. M., Boston, R. C., Panda, S., Hogenesch, J. B. & FitzGerald, G. A., Nov 1 2004, In : PLoS Biology. 2, 11

Research output: Contribution to journalArticle

Circadian Clocks
circadian rhythm
Clocks
homeostasis
Homeostasis
151 Citations (Scopus)

Histone Acetyltransferase-dependent Chromatin Remodeling and the Vascular Clock

Curtis, A. M., Seo, S. B., Westgate, E. J., Rudic, R. D., Smyth, E. M., Chakravarti, D., FitzGerald, G. A. & McNamara, P., Feb 20 2004, In : Journal of Biological Chemistry. 279, 8, p. 7091-7097 7 p.

Research output: Contribution to journalArticle

Histone Acetyltransferases
Chromatin Assembly and Disassembly
Gene expression
Chromatin
Blood Vessels
2005
103 Citations (Scopus)

Bioinformatic analysis of circadian gene oscillation in mouse aorta

Rudic, R. D., McNamara, P., Reilly, D., Grosser, T., Curtis, A. M., Price, T. S., Panda, S., Hogenesch, J. B. & FitzGerald, G. A., Oct 25 2005, In : Circulation. 112, 17, p. 2716-2724 9 p.

Research output: Contribution to journalArticle

Computational Biology
Aorta
Blood Vessels
Genes
Gene Expression
96 Citations (Scopus)

COX-2-derived prostacyclin modulates vascular remodeling

Rudic, R. D., Brinster, D., Cheng, Y., Fries, S., Song, W. L., Austin, S., Coffman, T. M. & FitzGerald, G. A., Jun 24 2005, In : Circulation research. 96, 12, p. 1240-1247 8 p.

Research output: Contribution to journalArticle

nimesulide
Epoprostenol
Cyclooxygenase 2
Cyclooxygenase 2 Inhibitors
8-epi-prostaglandin F2alpha
17 Citations (Scopus)

Peripheral clocks and the regulation of cardiovascular and metabolic function

Rudic, R. D., Curtis, A. M., Cheng, Y. & FitzGerald, G., Jan 1 2005, In : Methods in Enzymology. 393, p. 524-539 16 p., 27.

Research output: Contribution to journalArticle

Circadian Rhythm
Clocks
Biological Clocks
Physiology
Biological systems
2008
68 Citations (Scopus)

Paradoxical activation of endothelial nitric oxide synthase by NADPH oxidase

Zhang, Q., Malik, P., Pandey, D., Gupta, S., Jagnandan, D., De Chantemele, E. B., Banfi, B., Marrero, M. B., Rudic, R. D., Stepp, D. W. & Fulton, D. J. R., Sep 1 2008, In : Arteriosclerosis, thrombosis, and vascular biology. 28, 9, p. 1627-1633 7 p.

Research output: Contribution to journalArticle

Nitric Oxide Synthase Type III
NADPH Oxidase
Reactive Oxygen Species
Blood Vessels
Superoxides
32 Citations (Scopus)

Peripheral circadian clock rhythmicity is retained in the absence of adrenergic signaling

Reilly, D. F., Curtis, A. M., Cheng, Y., Westgate, E. J., Rudic, R. D., Paschos, G., Morris, J., Ouyang, M., Thomas, S. A. & FitzGerald, G. A., Jan 1 2008, In : Arteriosclerosis, thrombosis, and vascular biology. 28, 1, p. 121-126 6 p.

Research output: Contribution to journalArticle

Circadian Clocks
Periodicity
Adrenergic Agents
Terazosin
Epinephrine
16 Citations (Scopus)

Restoration of endothelin-1-induced impairment in endothelium-dependent relaxation by interleukin-10 in murine aortic rings

Zemse, S. M., Hilgers, R. H. P., Simkins, G. B., Rudic, R. D. & Webb, R. C., Aug 1 2008, In : Canadian Journal of Physiology and Pharmacology. 86, 8, p. 557-565 9 p.

Research output: Contribution to journalArticle

Endothelin-1
Interleukin-10
Endothelium
Acetylcholine
Anti-Inflammatory Agents
2009
43 Citations (Scopus)

Pressed for time: The circadian clock and hypertension

Rudic, R. D. & Fulton, D. J., Oct 1 2009, In : Journal of Applied Physiology. 107, 4, p. 1328-1338 11 p.

Research output: Contribution to journalReview article

Circadian Clocks
Hypertension
Cardiovascular Diseases
Blood Pressure
Water-Electrolyte Balance
80 Citations (Scopus)

Soluble epoxide inhibition is protective against cerebral ischemia via vascular and neural protection

Simpkins, A. N., Rudic, R. D., Schreihofer, D. A., Roy, S., Manhiani, M., Tsai, H. J., Hammock, B. D. & Imig, J. D., Jan 1 2009, In : American Journal of Pathology. 174, 6, p. 2086-2095 10 p.

Research output: Contribution to journalArticle

Epoxide Hydrolases
lauric acid
Epoxy Compounds
Brain Ischemia
Blood Vessels
31 Citations (Scopus)

Time is of the essence: Vascular implications of the circadian clock

Rudic, R. D., Oct 1 2009, In : Circulation. 120, 17, p. 1714-1721 8 p.

Research output: Contribution to journalReview article

Biological Clocks
Circadian Clocks
Circadian Rhythm
Endothelium
Blood Vessels
148 Citations (Scopus)

Vascular disease in mice with a dysfunctional circadian clock

Anea, C. B., Zhang, M., Stepp, D. W., Simkins, G. B., Reed, G., Fulton, D. J. & Daniel Rudic, R., Mar 24 2009, In : Circulation. 119, 11, p. 1510-1517 8 p.

Research output: Contribution to journalArticle

Circadian Clocks
Vascular Diseases
Blood Vessels
Circadian Rhythm
Critical Pathways
2010
41 Citations (Scopus)

Matrix metalloproteinase 2 and 9 dysfunction underlie vascular stiffness in circadian clock mutant mice

Anea, C. B., Irfan Ali, M., Osmond, J. M., Sullivan, J. C., Stepp, D. W., Merloiu, A. M. & Rudic, R. D., Dec 1 2010, In : Arteriosclerosis, thrombosis, and vascular biology. 30, 12, p. 2535-2543 9 p.

Research output: Contribution to journalArticle

Circadian Clocks
Vascular Stiffness
Matrix Metalloproteinase 2
Matrix Metalloproteinase 9
Knockout Mice
29 Citations (Scopus)
Nitric Oxide Synthase Type III
Nitric Oxide
Cell Membrane
von Willebrand Factor
N-Ethylmaleimide-Sensitive Proteins
32 Citations (Scopus)

Soluble epoxide hydrolase inhibition modulates vascular remodeling

Simpkins, A. N., Rudic, R. D., Roy, S., Tsai, H. J., Hammock, B. D. & Imig, J. D., Mar 1 2010, In : American Journal of Physiology - Heart and Circulatory Physiology. 298, 3, p. H795-H806

Research output: Contribution to journalArticle

Epoxide Hydrolases
Enzymes
Endothelium
Gene Deletion
Vascular System Injuries
2011
37 Citations (Scopus)

SUMO1 negatively regulates reactive oxygen species production from NADPH oxidases

Pandey, D., Chen, F., Patel, A., Wang, C. Y., Dimitropoulou, C., Patel, V. S., Rudic, R. D., Stepp, D. W. & Fulton, D. J., Jul 1 2011, In : Arteriosclerosis, thrombosis, and vascular biology. 31, 7, p. 1634-1642 9 p.

Research output: Contribution to journalArticle

NADPH Oxidase
Reactive Oxygen Species
Sumoylation
Ubiquitin
Ubiquitin-Conjugating Enzymes
42 Citations (Scopus)

Tissue-intrinsic dysfunction of circadian clock confers transplant arteriosclerosis

Cheng, B., Anea, C. B., Yao, L., Chen, F., Patel, V., Merloiu, A., Pati, P., Caldwell, R. W., Fulton, D. J. & Rudic, R. D., Oct 11 2011, In : Proceedings of the National Academy of Sciences of the United States of America. 108, 41, p. 17147-17152 6 p.

Research output: Contribution to journalArticle

Circadian Clocks
Arteriosclerosis
Transplants
Organ Transplantation
Vascular Grafting
2012
13 Citations (Scopus)

Endothelium derived nitric oxide synthase negatively regulates the PDGF-survivin pathway during Flow-Dependent vascular remodeling

Yu, J., Zhang, Y., Zhang, X., Rudic, R. D., Bauer, P. M., Altieri, D. C. & Sessa, W. C., Feb 15 2012, In : PloS one. 7, 2, e31495.

Research output: Contribution to journalArticle

platelet-derived growth factor
Nitric Oxide Synthase Type III
Platelet-Derived Growth Factor
nitric oxide synthase
endothelium
44 Citations (Scopus)

Expression and functional significance of NADPH oxidase 5 (Nox5) and its splice variants in human blood vessels

Pandey, D., Patel, A., Patel, V., Chen, F., Qian, J., Wang, Y., Barman, S. A., Venema, R. C., Stepp, D. W., Daniel Rudic, R. & Fulton, D. J. R., May 15 2012, In : American Journal of Physiology - Heart and Circulatory Physiology. 302, 10, p. H1919-H1928

Research output: Contribution to journalArticle

NADPH Oxidase
Blood Vessels
Vascular Smooth Muscle
Reactive Oxygen Species
Protein Isoforms
46 Citations (Scopus)

Increased superoxide and endothelial NO synthase uncoupling in blood vessels of Bmal1-knockout mice

Anea, C. B., Cheng, B., Sharma, S., Kumar, S., Caldwell, R. W., Yao, L., Ali, M. I., Merloiu, A. M., Stepp, D. W., Black, S. M., Fulton, D. J. R. & Rudic, R. D., Oct 12 2012, In : Circulation research. 111, 9, p. 1157-1165 9 p.

Research output: Contribution to journalArticle

Circadian Clocks
Knockout Mice
Nitric Oxide Synthase
Superoxides
Blood Vessels
50 Citations (Scopus)

Opposing actions of heat shock protein 90 and 70 regulate nicotinamide adenine dinucleotide phosphate oxidase stability and reactive oxygen species production

Chen, F., Yu, Y., Qian, J., Wang, Y., Cheng, B., Dimitropoulou, C., Patel, V. S., Chadli, A., Rudic, R. D., Stepp, D. W., Catravas, J. D. & Fulton, D. J., Dec 1 2012, In : Arteriosclerosis, thrombosis, and vascular biology. 32, 12, p. 2989-2999 11 p.

Research output: Contribution to journalArticle

HSP90 Heat-Shock Proteins
HSP70 Heat-Shock Proteins
NADP
Reactive Oxygen Species
Oxidoreductases
2013
15 Citations (Scopus)

Circadian Clock Control of Nox4 and Reactive Oxygen Species in the Vasculature

Anea, C. B., Zhang, M., Chen, F., Ali, M. I., Hart, C. M. M., Stepp, D. W., Kovalenkov, Y. O., Merloiu, A. M., Pati, P., Fulton, D. & Rudic, R. D., Oct 25 2013, In : PloS one. 8, 10, e78626.

Research output: Contribution to journalArticle

Circadian Clocks
circadian rhythm
Clocks
reactive oxygen species
Reactive Oxygen Species
2014
11 Citations (Scopus)

Hepatic overexpression of the prodomain of furin lessens progression of atherosclerosis and reduces vascular remodeling in response to injury

Lei, X., Basu, D., Li, Z., Zhang, M., Rudic, R. D., Jiang, X. C. & Jin, W., Jan 1 2014, In : Atherosclerosis. 236, 1

Research output: Contribution to journalArticle

Furin
Apolipoproteins B
Atherosclerosis
Liver
Wounds and Injuries
18 Citations (Scopus)

IL-19 reduces ligation-mediated neointimal hyperplasia by reducing vascular smooth muscle cell activation

Ellison, S., Gabunia, K., Richards, J. M., Kelemen, S. E., England, R. N., Rudic, R. D., Azuma, Y. T., Munroy, M. A., Eguchi, S. & Autieri, M. V., Jan 1 2014, In : American Journal of Pathology. 184, 7, p. 2134-2143 10 p.

Research output: Contribution to journalArticle

Vascular Smooth Muscle
Knockout Mice
Smooth Muscle Myocytes
Hyperplasia
Ligation
2015
7 Citations (Scopus)

Obesity Alters the Peripheral Circadian Clock in the Aorta and Microcirculation

Nernpermpisooth, N., Qiu, S., Mintz, J. D., Suvitayavat, W., Thirawarapan, S., Rudic, R. D., Fulton, D. J. & Stepp, D. W., Jan 1 2015, In : Microcirculation. 22, 4, p. 257-266 10 p.

Research output: Contribution to journalArticle

Circadian Clocks
Microcirculation
Aorta
Obesity
Obese Mice

The Cardiovascular Clock

Rudic, R. D., May 8 2015, Circadian Medicine. Wiley-Blackwell, p. 119-133 15 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Circadian Clocks
Blood Pressure
Circadian Rhythm
Animal Models
Endothelins
2016
11 Citations (Scopus)

Endotoxin disrupts circadian rhythms in macrophages via reactive oxygen species

Wang, Y., Pati, P., Xu, Y., Chen, F., Stepp, D. W., Huo, Y., Rudic, R. D. & Fulton, D. J., May 1 2016, In : PloS one. 11, 5, e0155075.

Research output: Contribution to journalArticle

Macrophages
endotoxins
Circadian Rhythm
Endotoxins
circadian rhythm
11 Citations (Scopus)

Low-Salt Diet and Circadian Dysfunction Synergize to Induce Angiotensin II-Dependent Hypertension in Mice

Pati, P., Fulton, D. J. R., Bagi, Z., Chen, F., Wang, Y., Kitchens, J., Cassis, L. A., Stepp, D. W. & Rudic, R. D., Mar 1 2016, In : Hypertension. 67, 3, p. 661-668 8 p.

Research output: Contribution to journalArticle

Sodium-Restricted Diet
Angiotensin II
Blood Pressure
Hypertension
Knockout Mice
2017
6 Citations (Scopus)

Differential Regulation of BMAL1, CLOCK, and Endothelial Signaling in the Aortic Arch and Ligated Common Carotid Artery

Shang, X., Pati, P., Anea, C. B., Fulton, D. J. R. & Rudic, R. D., Jan 1 2017, In : Journal of Vascular Research. 53, 5-6, p. 269-278 10 p.

Research output: Contribution to journalArticle

Common Carotid Artery
Thoracic Aorta
Nitric Oxide Synthase Type III
Circadian Clocks
Acetylcholine
7 Citations (Scopus)

Role of Adipose Tissue Endothelial ADAM17 in Age-Related Coronary Microvascular Dysfunction

Dou, H., Feher, A., Davila, A. C., Romero, M. J., Patel, V. S., Kamath, V. M., Gooz, M. B., Rudic, R. D., Lucas, R., Fulton, D. J., Weintraub, N. L. & Bagi, Z., Jun 1 2017, In : Arteriosclerosis, thrombosis, and vascular biology. 37, 6, p. 1180-1193 14 p.

Research output: Contribution to journalArticle

Adipose Tissue
Caveolin 1
Tumor Necrosis Factor-alpha
Obesity
Dilatation
2018
7 Citations (Scopus)

Hsp70 suppresses mitochondrial reactive oxygen species and preserves pulmonary microvascular barrier integrity following exposure to bacterial toxins

Li, X., Yu, Y., Gorshkov, B., Haigh, S., Bordan, Z., Weintraub, D., Rudic, R. D., Chakraborty, T., Barman, S. A., Verin, A. D., Su, Y., Lucas, R., Stepp, D. W., Chen, F. & Fulton, D. J., Jun 12 2018, In : Frontiers in immunology. 9, JUN, 1309.

Research output: Contribution to journalArticle

Bacterial Toxins
geranylgeranylacetone
Reactive Oxygen Species
Lung
Pneumonia
2019

Old and new roles and evolving complexities of cardiovascular clocks

Xu, Y., Pi, W. & Rudic, R. D., Jan 1 2019, In : Yale Journal of Biology and Medicine. 92, 2, p. 283-290 8 p.

Research output: Contribution to journalReview article

Circadian Rhythm
Clocks
Cardiovascular System
Cardiovascular system
Circadian Clocks