• 4623 Citations
  • 28 h-Index
19962019

Research output per year

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Research Output

  • 4623 Citations
  • 28 h-Index
  • 40 Article
  • 5 Review article
  • 1 Chapter
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Article

Acute modulation of endothelial Akt/PKB activity alters nitric oxide-dependent vasomotor activity in vivo

Luo, Z., Fujio, Y., Kureishi, Y., Rudic, R. D., Daumerie, G., Fulton, D., Sessa, W. C. & Walsh, K., Aug 2000, In : Journal of Clinical Investigation. 106, 4, p. 493-499 7 p.

Research output: Contribution to journalArticle

166 Scopus citations

A functional genomics strategy reveals rora as a component of the mammalian circadian clock

Sato, T. K., Panda, S., Miraglia, L. J., Reyes, T. M., Rudic, R. D., McNamara, P., Naik, K. A., Fitzgerald, G. A., Kay, S. A. & Hogenesch, J. B., Aug 19 2004, In : Neuron. 43, 4, p. 527-537 11 p.

Research output: Contribution to journalArticle

616 Scopus citations

Bioinformatic analysis of circadian gene oscillation in mouse aorta

Rudic, R. D., McNamara, P., Reilly, D., Grosser, T., Curtis, A. M., Price, T. S., Panda, S., Hogenesch, J. B. & FitzGerald, G. A., Oct 25 2005, In : Circulation. 112, 17, p. 2716-2724 9 p.

Research output: Contribution to journalArticle

103 Scopus citations

BMAL1 and CLOCK, two essential components of the circadian clock, are involved in glucose homeostasis

Rudic, R. D., McNamara, P., Curtis, A. M., Boston, R. C., Panda, S., Hogenesch, J. B. & FitzGerald, G. A., Nov 1 2004, In : PLoS Biology. 2, 11

Research output: Contribution to journalArticle

650 Scopus citations

Circadian Clock Control of Nox4 and Reactive Oxygen Species in the Vasculature

Anea, C. B., Zhang, M., Chen, F., Ali, M. I., Hart, C. M. M., Stepp, D. W., Kovalenkov, Y. O., Merloiu, A. M., Pati, P., Fulton, D. & Rudic, R. D., Oct 25 2013, In : PloS one. 8, 10, e78626.

Research output: Contribution to journalArticle

17 Scopus citations

COX-2-derived prostacyclin modulates vascular remodeling

Rudic, R. D., Brinster, D., Cheng, Y., Fries, S., Song, W. L., Austin, S., Coffman, T. M. & FitzGerald, G. A., Jun 24 2005, In : Circulation research. 96, 12, p. 1240-1247 8 p.

Research output: Contribution to journalArticle

96 Scopus citations

Differential Regulation of BMAL1, CLOCK, and Endothelial Signaling in the Aortic Arch and Ligated Common Carotid Artery

Shang, X., Pati, P., Anea, C. B., Fulton, D. J. R. & Rudic, R. D., Jan 1 2017, In : Journal of Vascular Research. 53, 5-6, p. 269-278 10 p.

Research output: Contribution to journalArticle

7 Scopus citations

Direct evidence for the importance of endothelium-derived nitric oxide in vascular remodeling

Rudic, R. D., Shesely, E. G., Maeda, N., Smithies, O., Segal, S. S. & Sessa, W. C., Feb 15 1998, In : Journal of Clinical Investigation. 101, 4, p. 731-736 6 p.

Research output: Contribution to journalArticle

639 Scopus citations

Endothelium derived nitric oxide synthase negatively regulates the PDGF-survivin pathway during Flow-Dependent vascular remodeling

Yu, J., Zhang, Y., Zhang, X., Rudic, R. D., Bauer, P. M., Altieri, D. C. & Sessa, W. C., Feb 15 2012, In : PloS one. 7, 2, e31495.

Research output: Contribution to journalArticle

14 Scopus citations

Endotoxin disrupts circadian rhythms in macrophages via reactive oxygen species

Wang, Y., Pati, P., Xu, Y., Chen, F., Stepp, D. W., Huo, Y., Rudic, R. D. & Fulton, D. J. R., May 1 2016, In : PloS one. 11, 5, e0155075.

Research output: Contribution to journalArticle

12 Scopus citations

Expression and functional significance of NADPH oxidase 5 (Nox5) and its splice variants in human blood vessels

Pandey, D., Patel, A., Patel, V., Chen, F., Qian, J., Wang, Y., Barman, S. A., Venema, R. C., Stepp, D. W., Daniel Rudic, R. & Fulton, D. J. R., May 15 2012, In : American Journal of Physiology - Heart and Circulatory Physiology. 302, 10, p. H1919-H1928

Research output: Contribution to journalArticle

45 Scopus citations

Functional reconstitution of endothelial nitric oxide synthase reveals the importance of serine 1179 in endothelium-dependent vasomotion

Scotland, R. S., Morales-Ruiz, M., Chen, Y., Yu, J., Rudic, R. D., Fulton, D., Gratton, J. P. & Sessa, W. C., May 3 2002, In : Circulation research. 90, 8, p. 904-910 7 p.

Research output: Contribution to journalArticle

94 Scopus citations

Hepatic overexpression of the prodomain of furin lessens progression of atherosclerosis and reduces vascular remodeling in response to injury

Lei, X., Basu, D., Li, Z., Zhang, M., Rudic, R. D., Jiang, X. C. & Jin, W., Sep 2014, In : Atherosclerosis. 236, 1, p. 121e130

Research output: Contribution to journalArticle

11 Scopus citations

Histone Acetyltransferase-dependent Chromatin Remodeling and the Vascular Clock

Curtis, A. M., Seo, S. B., Westgate, E. J., Rudic, R. D., Smyth, E. M., Chakravarti, D., FitzGerald, G. A. & McNamara, P., Feb 20 2004, In : Journal of Biological Chemistry. 279, 8, p. 7091-7097 7 p.

Research output: Contribution to journalArticle

155 Scopus citations

Hsp70 suppresses mitochondrial reactive oxygen species and preserves pulmonary microvascular barrier integrity following exposure to bacterial toxins

Li, X., Yu, Y., Gorshkov, B., Haigh, S., Bordan, Z., Weintraub, D., Rudic, R. D., Chakraborty, T., Barman, S. A., Verin, A. D., Su, Y., Lucas, R., Stepp, D. W., Chen, F. & Fulton, D. J., Jun 12 2018, In : Frontiers in immunology. 9, JUN, 1309.

Research output: Contribution to journalArticle

8 Scopus citations

Human T cells infiltrate and injure pig coronary artery grafts with activated but not quiescent endothelium in immunodeficient mouse hosts

Tereb, D. A., Kirkiles-Smith, N. C., Kim, R. W., Wang, Y., Rudic, R. D., Schechner, J. S., Lorber, M. I., Bothwell, A. L. M., Pober, J. S. & Tellides, G., Jun 15 2001, In : Transplantation. 71, 11, p. 1622-1630 9 p.

Research output: Contribution to journalArticle

20 Scopus citations

IL-19 reduces ligation-mediated neointimal hyperplasia by reducing vascular smooth muscle cell activation

Ellison, S., Gabunia, K., Richards, J. M., Kelemen, S. E., England, R. N., Rudic, D., Azuma, Y. T., Munroy, M. A., Eguchi, S. & Autieri, M. V., Jul 2014, In : American Journal of Pathology. 184, 7, p. 2134-2143 10 p.

Research output: Contribution to journalArticle

19 Scopus citations

Increased superoxide and endothelial NO synthase uncoupling in blood vessels of Bmal1-knockout mice

Anea, C. B., Cheng, B., Sharma, S., Kumar, S., Caldwell, R. W., Yao, L., Ali, M. I., Merloiu, A. M., Stepp, D. W., Black, S. M., Fulton, D. J. R. & Rudic, R. D., Oct 12 2012, In : Circulation research. 111, 9, p. 1157-1165 9 p.

Research output: Contribution to journalArticle

51 Scopus citations

In vivo delivery of the caveolin-1 scaffolding domain inhibits nitric oxide synthesis and reduces inflammation

Bucci, M., Gratton, J. P., Rudic, R. D., Acevedo, L., Roviezzo, F., Cirino, G. & Sessa, W. C., Dec 1 2000, In : Nature Medicine. 6, 12, p. 1362-1367 6 p.

Research output: Contribution to journalArticle

418 Scopus citations

Low-Salt Diet and Circadian Dysfunction Synergize to Induce Angiotensin II-Dependent Hypertension in Mice

Pati, P., Fulton, D. J. R., Bagi, Z., Chen, F., Wang, Y., Kitchens, J., Cassis, L. A., Stepp, D. W. & Rudic, R. D., Mar 1 2016, In : Hypertension. 67, 3, p. 661-668 8 p.

Research output: Contribution to journalArticle

12 Scopus citations

Matrix metalloproteinase 2 and 9 dysfunction underlie vascular stiffness in circadian clock mutant mice

Anea, C. B., Irfan Ali, M., Osmond, J. M., Sullivan, J. C., Stepp, D. W., Merloiu, A. M. & Rudic, R. D., Dec 1 2010, In : Arteriosclerosis, thrombosis, and vascular biology. 30, 12, p. 2535-2543 9 p.

Research output: Contribution to journalArticle

41 Scopus citations

Nitric oxide in endothelial dysfunction and vascular remodeling: Clinical correlates and experimental links

Rudic, R. D. & Sessa, W. C., Jan 1 1999, In : American journal of human genetics. 64, 3, p. 673-677 5 p.

Research output: Contribution to journalArticle

82 Scopus citations

Nitric oxide-releasing aspirin decreases vascular injury by reducing inflammation and promoting apoptosis

Yu, J., Rudic, R. D. & Sessa, W. C., Jan 1 2002, In : Laboratory Investigation. 82, 7, p. 825-832 8 p.

Research output: Contribution to journalArticle

28 Scopus citations

Nitric oxide synthase inhibitors attenuate transforming-growth-factor- β1-stimulated capillary organization in vitro

Papapetropoulos, A., Desai, K. M., Rudic, R. D., Mayer, B., Zhang, R., Ruiz-Torres, M. P., García-Cardeña, G., Madri, J. A. & Sessa, W. C., May 17 1997, In : American Journal of Pathology. 150, 5, p. 1835-1844 10 p.

Research output: Contribution to journalArticle

108 Scopus citations

Obesity Alters the Peripheral Circadian Clock in the Aorta and Microcirculation

Nernpermpisooth, N., Qiu, S., Mintz, J. D., Suvitayavat, W., Thirawarapan, S., Rudic, R. D., Fulton, D. J. & Stepp, D. W., Jan 1 2015, In : Microcirculation. 22, 4, p. 257-266 10 p.

Research output: Contribution to journalArticle

8 Scopus citations

Opposing actions of heat shock protein 90 and 70 regulate nicotinamide adenine dinucleotide phosphate oxidase stability and reactive oxygen species production

Chen, F., Yu, Y., Qian, J., Wang, Y., Cheng, B., Dimitropoulou, C., Patel, V., Chadli, A., Rudic, R. D., Stepp, D. W., Catravas, J. D. & Fulton, D. J. R., Dec 1 2012, In : Arteriosclerosis, thrombosis, and vascular biology. 32, 12, p. 2989-2999 11 p.

Research output: Contribution to journalArticle

50 Scopus citations

Paradoxical activation of endothelial nitric oxide synthase by NADPH oxidase

Zhang, Q., Malik, P., Pandey, D., Gupta, S., Jagnandan, D., De Chantemele, E. B., Banfi, B., Marrero, M. B., Rudic, R. D., Stepp, D. W. & Fulton, D. J. R., Sep 1 2008, In : Arteriosclerosis, thrombosis, and vascular biology. 28, 9, p. 1627-1633 7 p.

Research output: Contribution to journalArticle

69 Scopus citations

Peripheral circadian clock rhythmicity is retained in the absence of adrenergic signaling

Reilly, D. F., Curtis, A. M., Cheng, Y., Westgate, E. J., Rudic, R. D., Paschos, G., Morris, J., Ouyang, M., Thomas, S. A. & FitzGerald, G. A., Jan 1 2008, In : Arteriosclerosis, thrombosis, and vascular biology. 28, 1, p. 121-126 6 p.

Research output: Contribution to journalArticle

33 Scopus citations

Peripheral clocks and the regulation of cardiovascular and metabolic function

Rudic, R. D., Curtis, A. M., Cheng, Y. & FitzGerald, G., Jan 1 2005, In : Methods in Enzymology. 393, p. 524-539 16 p., 27.

Research output: Contribution to journalArticle

17 Scopus citations

Regulation of CLOCK and MOP4 by nuclear hormone receptors in the vasculature: A humoral mechanism to reset a peripheral clock

McNamara, P., Seo, S. B., Rudic, R. D., Sehgal, A., Chakravarti, D. & FitzGerald, G. A., Jun 29 2001, In : Cell. 105, 7, p. 877-889 13 p.

Research output: Contribution to journalArticle

350 Scopus citations

Restoration of endothelin-1-induced impairment in endothelium-dependent relaxation by interleukin-10 in murine aortic rings

Zemse, S. M., Hilgers, R. H. P., Simkins, G. B., Rudic, R. D. & Webb, R. C., Aug 1 2008, In : Canadian Journal of Physiology and Pharmacology. 86, 8, p. 557-565 9 p.

Research output: Contribution to journalArticle

16 Scopus citations

Role of Adipose Tissue Endothelial ADAM17 in Age-Related Coronary Microvascular Dysfunction

Dou, H., Feher, A., Davila, A. C., Romero, M. J., Patel, V. S., Kamath, V. M., Gooz, M. B., Rudic, R. D., Lucas, R., Fulton, D. J., Weintraub, N. L. & Bagi, Z., Jun 1 2017, In : Arteriosclerosis, thrombosis, and vascular biology. 37, 6, p. 1180-1193 14 p.

Research output: Contribution to journalArticle

7 Scopus citations
29 Scopus citations

Role of nitric oxide in capillary organization and differentiation

Pesai, K. M., Rudic, R. D., García-Cardeña, G., Madri, J. A. & Sessa, W. C., Dec 1 1996, In : FASEB Journal. 10, 3

Research output: Contribution to journalArticle

Soluble epoxide hydrolase inhibition modulates vascular remodeling

Simpkins, A. N., Rudic, R. D., Roy, S., Tsai, H. J., Hammock, B. D. & Imig, J. D., Mar 1 2010, In : American Journal of Physiology - Heart and Circulatory Physiology. 298, 3, p. H795-H806

Research output: Contribution to journalArticle

33 Scopus citations

Soluble epoxide inhibition is protective against cerebral ischemia via vascular and neural protection

Simpkins, A. N., Rudic, R. D., Schreihofer, D. A., Roy, S., Manhiani, M., Tsai, H. J., Hammock, B. D. & Imig, J. D., Jun 2009, In : American Journal of Pathology. 174, 6, p. 2086-2095 10 p.

Research output: Contribution to journalArticle

80 Scopus citations

SUMO1 negatively regulates reactive oxygen species production from NADPH oxidases

Pandey, D., Chen, F., Patel, A., Wang, C. Y., Dimitropoulou, C., Patel, V. S., Rudic, R. D., Stepp, D. W. & Fulton, D. J., Jul 1 2011, In : Arteriosclerosis, thrombosis, and vascular biology. 31, 7, p. 1634-1642 9 p.

Research output: Contribution to journalArticle

37 Scopus citations

Temporal events underlying arterial remodeling after chronic flow reduction in mice: Correlation of structural changes with a deficit in basal nitric oxide synthesis

Rudic, R. D., Bucci, M., Fulton, D., Segal, S. S. & Sessa, W. C., Jun 9 2000, In : Circulation research. 86, 11, p. 1160-1166 7 p.

Research output: Contribution to journalArticle

52 Scopus citations

Tissue-intrinsic dysfunction of circadian clock confers transplant arteriosclerosis

Cheng, B., Anea, C. B., Yao, L., Chen, F., Patel, V., Merloiu, A., Pati, P., Caldwell, R. W., Fulton, D. J. & Rudic, R. D., Oct 11 2011, In : Proceedings of the National Academy of Sciences of the United States of America. 108, 41, p. 17147-17152 6 p.

Research output: Contribution to journalArticle

42 Scopus citations

Vascular disease in mice with a dysfunctional circadian clock

Anea, C. B., Zhang, M., Stepp, D. W., Simkins, G. B., Reed, G., Fulton, D. J. & Daniel Rudic, R., Mar 24 2009, In : Circulation. 119, 11, p. 1510-1517 8 p.

Research output: Contribution to journalArticle

151 Scopus citations