• 2068 Citations
  • 27 h-Index
19952019

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Article
2019
Open Access

Deficiency of metabolite sensing receptor HCA2 impairs the salutary effect of niacin in hemorrhagic shock

Subramani, K., Chu, X., Warren, M., Lee, M., Lu, S., Singh, N. & Raju, R. P., Mar 1 2019, In : Biochimica et Biophysica Acta - Molecular Basis of Disease. 1865, 3, p. 688-695 8 p.

Research output: Contribution to journalArticle

2 Scopus citations
Open Access
6 Scopus citations

NLRX1 regulation following acute mitochondrial injury

Chu, X., Wu, S. & Raju, R., Jan 1 2019, In : Frontiers in immunology. 10, OCT, 2431.

Research output: Contribution to journalArticle

Open Access
2018

Effect of plasma-derived extracellular vesicles on erythrocyte deformability in polymicrobial sepsis

Subramani, K., Raju, S. P., Chu, X., Warren, M., Pandya, C. D., Hoda, N., Fulzele, S. & Raju, R., Dec 2018, In : International Immunopharmacology. 65, p. 244-247 4 p.

Research output: Contribution to journalArticle

1 Scopus citations

Kidney-targeted inhibition of protein kinase C-α ameliorates nephrotoxic nephritis with restoration of mitochondrial dysfunction

Kvirkvelia, N., McMenamin, M., Warren, M., Jadeja, R. N., Kodeboyina, S. K., Sharma, A., Zhi, W., O'Connor, P. M., Raju, R., Lucas, R. & Madaio, M. P., Aug 2018, In : Kidney International. 94, 2, p. 280-291 12 p.

Research output: Contribution to journalArticle

2 Scopus citations
2017

Mitochondrial dysfunction in rat splenocytes following hemorrhagic shock

Warren, M., Subramani, K., Schwartz, R. & Raju, R., Oct 2017, In : Biochimica et Biophysica Acta - Molecular Basis of Disease. 1863, 10, p. 2526-2533 8 p.

Research output: Contribution to journalArticle

10 Scopus citations

Mitochondrial targeting by dichloroacetate improves outcome following hemorrhagic shock

Subramani, K., Lu, S., Warren, M., Chu, X., Flores Toque, H. A., Caldwell, R. W., Diamond, M. P. & Raju, R. P., Dec 1 2017, In : Scientific reports. 7, 1, 2653.

Research output: Contribution to journalArticle

8 Scopus citations
2016

Alteration of cytokine profile following hemorrhagic shock

Lu, S., Aguilar, A., Subramani, K., Poulose, N., Ayub, A. & Raju, R. P., May 1 2016, In : Cytokine. 81, p. 35-38 4 p.

Research output: Contribution to journalArticle

8 Scopus citations
2015

Resveratrol improves survival and prolongs life following hemorrhagic shock

Ayub, A., Poulose, N. & Raju, R. P., Apr 13 2015, In : Molecular Medicine. 21, p. 305-312 8 p.

Research output: Contribution to journalArticle

13 Scopus citations
2014

A new cecal slurry preparation protocol with improved long-term reproducibility for animal models of sepsis

Starr, M. E., Steele, A. M., Saito, M., Hacker, B. J., Evers, B. M., Saito, H. & Raju, R., Dec 22 2014, In : PloS one. 9, 12, e115705.

Research output: Contribution to journalArticle

30 Scopus citations

Resveratrol restores sirtuin 1 (SIRT1) activity and pyruvate dehydrogenase kinase 1 (PDK1) expression after hemorrhagic injury in a rat model

Jian, B., Yang, S., Chaudry, I. H. & Raju, R., Jan 1 2014, In : Molecular Medicine. 20, 1, p. 10-16 7 p.

Research output: Contribution to journalArticle

24 Scopus citations

Resveratrol suppresses expression of VEGF by human retinal pigment epithelial cells: Potential nutraceutical for Age-related macular degeneration

Nagineni, C. N., Raju, R. P., Nagineni, K. K., Kommineni, V. K., Cherukuri, A., Krishnan Kutty, R., Hooks, J. J. & Detrick, B., Jan 1 2014, In : Aging and Disease. 5, 2, p. 88-100 13 p.

Research output: Contribution to journalArticle

2 Scopus citations

Resveratrol suppresses expression of VEGF by human retinal pigment epithelial cells: Potential nutraceutical for age-related macular degeneration

Nagineni, C. N., Raju, R. P., Nagineni, K. K., Kommineni, V. K., Cherukuri, A., Kutty, R. K., Hooks, J. J. & Detrick, B., Jan 1 2014, In : Aging and Disease. 5, 2, p. 88-100 13 p.

Research output: Contribution to journalArticle

45 Scopus citations
2013

Fatigue-Related Gene Networks Identified in CD14+ Cells Isolated From HIV-Infected Patients-Part I: Research Findings

Voss, J. G., Dobra, A., Morse, C., Kovacs, J. A., Danner, R. L., Munson, P. J., Logan, C., Rangel, Z., Adelsberger, J. W., McLaughlin, M., Adams, L. D., Raju, R. & Dalakas, M. C., Feb 12 2013, In : Biological research for nursing. 15, 2, p. 137-151 15 p.

Research output: Contribution to journalArticle

4 Scopus citations

Fatigue-Related Gene Networks Identified in CD14+ Cells Isolated From HIV-Infected Patients-Part II: Statistical Analysis

Voss, J. G., Dobra, A., Morse, C., Kovacs, J. A., Raju, R., Danner, R. L., Munson, P. J., Logan, C., Rangel, Z., Adelsberger, J. W., McLaughlin, M., Adams, L. D. & Dalakas, M. C., Feb 12 2013, In : Biological research for nursing. 15, 2, p. 152-159 8 p.

Research output: Contribution to journalArticle

3 Scopus citations

Transforming growth factor-β regulates the expression of anosmin (KAL-1) in human retinal pigment epithelial cells

Raju, R., Jian, B., Hooks, J. J. & Nagineni, C. N., Mar 1 2013, In : Cytokine. 61, 3, p. 724-727 4 p.

Research output: Contribution to journalArticle

5 Scopus citations
2012

Provision of an explanation for the inefficacy of immunotherapy in sporadic inclusion body myositis: Quantitative assessment of inflammation and β-amyloid in the muscle

Zschüntzsch, J., Voss, J., Creus, K., Sehmisch, S., Raju, R., Dalakas, M. C. & Schmidt, J., Dec 1 2012, In : Arthritis and Rheumatism. 64, 12, p. 4094-4103 10 p.

Research output: Contribution to journalArticle

21 Scopus citations

Resveratrol improves cardiac contractility following trauma-hemorrhage by modulating Sirt1

Jian, B., Yang, S., Chaudry, I. H. & Raju, R., Feb 1 2012, In : Molecular Medicine. 18, 2, p. 209-214 6 p.

Research output: Contribution to journalArticle

45 Scopus citations
2011

Aging influences cardiac mitochondrial gene expression and cardiovascular function following hemorrhage injury

Jian, B., Yang, S., Chen, D., Zou, L., Chatham, J. C., Chaudry, I. & Raju, R., May 1 2011, In : Molecular Medicine. 17, 5-6, p. 542-549 8 p.

Research output: Contribution to journalArticle

18 Scopus citations

Influence of aging and hemorrhage injury on Sirt1 expression: Possible role of myc-Sirt1 regulation in mitochondrial function

Jian, B., Yang, S., Chen, D., Chaudry, I. & Raju, R., Nov 1 2011, In : Biochimica et Biophysica Acta - Molecular Basis of Disease. 1812, 11, p. 1446-1451 6 p.

Research output: Contribution to journalArticle

18 Scopus citations
2010

Effect of estrogen on mitochondrial function and intracellular stress markers in rat liver and kidney following trauma-hemorrhagic shock and prolonged hypotension

Kozlov, A. V., Catharina Duvigneau, J., Hyatt, T. C., Raju, R., Behling, T., Hartl, R. T., Staniek, K., Miller, I., Gregor, W., Redl, H. & Chaudry, I. H., Jan 1 2010, In : Molecular Medicine. 16, 7-8, p. 254-261 8 p.

Research output: Contribution to journalArticle

25 Scopus citations

Hypoxia-induced alteration of mitochondrial genes in cardiomyocytes: Role of Bnip3 and Pdk1

Jian, B., Wang, D., Chen, D., Voss, J., Chaudry, I. & Raju, R., Aug 2010, In : Shock. 34, 2, p. 169-175 7 p.

Research output: Contribution to journalArticle

23 Scopus citations
2009

Anosmin-1 involved in neuronal cell migration is hypoxia inducible and cancer regulated

Jian, B., Nagineni, C. N., Meleth, S., Grizzle, W., Bland, K., Chaudry, I. & Raju, R., Nov 15 2009, In : Cell Cycle. 8, 22, p. 3770-3776 7 p.

Research output: Contribution to journalArticle

19 Scopus citations

Placebo-controlled trial of rituximab in IgM anti-myelin-associated glycoprotein antibody demyelinating neuropathy

Dalakas, M. C., Rakocevic, G., Salajegheh, M., Dambrosia, J. M., Hahn, A. F., Raju, R. P. & McElroy, B., Mar 1 2009, In : Annals of Neurology. 65, 3, p. 286-293 8 p.

Research output: Contribution to journalArticle

196 Scopus citations

Suppression of activation and costimulatory signaling in splenic CD4 + T cells after trauma-hemorrhage reduces t-cell function: A mechanism of post-traumatic immune suppression

Hsieh, C. H., Hsu, J. T., Hsieh, Y. C., Frink, M., Raju, R., Hubbard, W. J., Bland, K. I. & Chaudry, I. H., Jan 1 2009, In : American Journal of Pathology. 175, 4, p. 1504-1514 11 p.

Research output: Contribution to journalArticle

16 Scopus citations
2008

Activation of endoplasmic reticulum stress response following trauma-hemorrhage

Jian, B., Hsieh, C. H., Chen, J., Choudhry, M., Bland, K., Chaudry, I. & Raju, R., Nov 1 2008, In : Biochimica et Biophysica Acta - Molecular Basis of Disease. 1782, 11, p. 621-626 6 p.

Research output: Contribution to journalArticle

37 Scopus citations

A focused microarray to study human mitochondrial and nuclear gene expression

Voss, J. G., Raju, R. P., Logun, C., Danner, R. L., Munson, P. J., Rangel, Z. & Dalakas, M. C., Apr 1 2008, In : Biological Research For Nursing. 9, 4, p. 272-279 8 p.

Research output: Contribution to journalArticle

10 Scopus citations

Flutamide protects against trauma-hemorrhage-induced liver injury via attenuation of the inflammatory response, oxidative stress, and apopotosis

Kan, W. H., Hsieh, C. H., Schwacha, M. G., Choudhry, M. A., Raju, R., Bland, K. I. & Chaudry, I. H., Aug 1 2008, In : Journal of Applied Physiology. 105, 2, p. 595-602 8 p.

Research output: Contribution to journalArticle

28 Scopus citations

Selective inhibition of iNOS attenuates trauma-hemorrhage/resuscitation- induced hepatic injury

Kan, W. H., Hsu, J. T., Schwacha, M. G., Choudhry, M. A., Raju, R., Bland, K. I. & Chaudry, I. H., Oct 1 2008, In : Journal of Applied Physiology. 105, 4, p. 1076-1082 7 p.

Research output: Contribution to journalArticle

35 Scopus citations
2007

Absence of upregulated genes associated with protein accumulations in desmin myopathy

Raju, R. & Dalakas, M. C., Mar 1 2007, In : Muscle and Nerve. 35, 3, p. 386-388 3 p.

Research output: Contribution to journalArticle

5 Scopus citations

Immune response modulation by curcumin in a latex allergy model

Kurup, V. P., Barrios, C. S., Raju, R., Johnson, B. D., Levy, M. B. & Fink, J. N., Mar 1 2007, In : Clinical and Molecular Allergy. 5, 1.

Research output: Contribution to journalArticle

55 Scopus citations

Inclusion body myositis with human immunodeficiency virus infection: Four cases with clonal expansion of viral-specific T cells

Dalakas, M. C., Rakocevic, G., Shatunov, A., Goldfarb, L., Raju, R. P. & Salajegheh, M., May 1 2007, In : Annals of Neurology. 61, 5, p. 466-475 10 p.

Research output: Contribution to journalArticle

60 Scopus citations

T cell receptor profiling in muscle and blood lymphocytes in sporadic inclusion body myositis

Salajegheh, M., Rakocevic, G., Raju, R. P., Shatunov, A., Goldfarb, L. G. & Dalakas, M. C., Jan 1 2007, In : Neurology. 69, 17, p. 1672-1679 8 p.

Research output: Contribution to journalArticle

39 Scopus citations

Upregulation of thrombospondin-1(TSP-1) and its binding partners, CD36 and CD47, in sporadic inclusion body myositis

Salajegheh, M., Raju, R., Schmidt, J. & Dalakas, M. C., Jul 1 2007, In : Journal of Neuroimmunology. 187, 1-2, p. 166-174 9 p.

Research output: Contribution to journalArticle

16 Scopus citations
2006

Autoimmunity to GABAA-receptor-associated protein in stiff-person syndrome

Raju, R., Rakocevic, G., Chen, Z., Hoehn, G., Semino-Mora, C., Shi, W., Olsen, R. & Dalakas, M. C., Dec 1 2006, In : Brain. 129, 12, p. 3270-3276 7 p.

Research output: Contribution to journalArticle

90 Scopus citations

Stiff person syndrome with cerebellar disease and high-titer anti-GAD antibodies

Rakocevic, G., Raju, R. P., Semino-Mora, C. & Dalakas, M. C., Sep 1 2006, In : Neurology. 67, 6, p. 1068-1070 3 p.

Research output: Contribution to journalArticle

57 Scopus citations
2005

Analysis of GAD65 autoantibodies in Stiff-Person syndrome patients

Raju, R., Foote, J., Banga, J. P., Hall, T. R., Padoa, C. J., Dalakas, M. C., Ortqvist, E. & Hampe, C. S., Dec 1 2005, In : Journal of Immunology. 175, 11, p. 7755-7762 8 p.

Research output: Contribution to journalArticle

112 Scopus citations
123 Scopus citations

Profile of gene expression in a murine model of allergic bronchopulmonary aspergillosis

Kurup, V. P., Raju, R. & Manickam, P., Jul 1 2005, In : Infection and Immunity. 73, 7, p. 4381-4384 4 p.

Research output: Contribution to journalArticle

8 Scopus citations
2004

Anti-glutamic acid decarboxylase antibodies in the serum and cerebrospinal fluid of patients with stiff-person syndrome: Correlation with clinical severity

Rakocevic, G., Raju, R. & Dalakas, M. C., Jun 1 2004, In : Archives of Neurology. 61, 6, p. 902-904 3 p.

Research output: Contribution to journalArticle

83 Scopus citations
2003

Alloimmune induction of endothelial cell-derived interferon-γ-inducible chemokines

Raju, R., Malloy, A., Shah, T., Smith, R., Oaks, M. & Hosenpud, J. D., Apr 15 2003, In : Transplantation. 75, 7, p. 1072-1074 3 p.

Research output: Contribution to journalArticle

9 Scopus citations

A T-linker strategy for modification and directional cloning of PCR products.

Horton, R. M., Raju, R. P. & Conti-Fine, B. M., Jan 1 2003, In : Methods in molecular biology (Clifton, N.J.). 226, p. 475-484 10 p.

Research output: Contribution to journalArticle

Evidence of a diverse T cell receptor repertoire for acetylcholine receptor, the autoantigen of myasthenia gravis

Infante, A. J., Baillargeon, J., Kraig, E., Lott, L., Jackson, C., Hämmerling, G. J., Raju, R. & David, C., Sep 2003, In : Journal of Autoimmunity. 21, 2, p. 167-174 8 p.

Research output: Contribution to journalArticle

16 Scopus citations

Expression of IFN-γ-inducible chemokines in inclusion body myositis

Raju, R., Vasconcelos, O., Granger, R. & Dalakas, M. C., Aug 2003, In : Journal of Neuroimmunology. 141, 1-2, p. 125-131 7 p.

Research output: Contribution to journalArticle

57 Scopus citations
2002

Cryptic determinants and promiscuous sequences on human acetylcholine receptor: HLA-dependent dichotomy in T-cell function

Raju, R., Marietta, E., Vinasco, J., Conti-Fine, B. M., Infante, A. J. & David, C. S., Apr 23 2002, In : Human Immunology. 63, 4, p. 237-247 11 p.

Research output: Contribution to journalArticle

4 Scopus citations

GNE mutations in an American family with quadriceps-sparing IBM and lack of mutations in s-IBM

Vasconcelos, O. M., Raju, R. & Dalakas, M. C., Dec 10 2002, In : Neurology. 59, 11, p. 1776-1779 4 p.

Research output: Contribution to journalArticle

38 Scopus citations

Modulation of insulitis and type 1 diabetes by transgenic HLA-DR3 and DQ8 in NOD mice lacking endogenous MHC class II

Kudva, Y. C., Rajagopalan, G., Raju, R., Abraham, R. S., Smart, M., Hanson, J. & David, C. S., Nov 1 2002, In : Human Immunology. 63, 11, p. 987-999 13 p.

Research output: Contribution to journalArticle

18 Scopus citations
2001

Acetylcholine receptor peptide recognition in HLA DR3-transgenic mice: In vivo responses correlate with MHC-peptide binding

Raju, R., Spack, E. G. & David, C. S., Jul 15 2001, In : Journal of Immunology. 167, 2, p. 1118-1124 7 p.

Research output: Contribution to journalArticle

15 Scopus citations
1998

Acetylcholine receptor-specific CD4+ T cells in myasthenia gravis patients have individual, but restricted TCR Vβ usage

Raju, R., Navaneetham, D., Protti, M. P., Horton, R. M., Hoppe, B. L., Howard, J. & Conti-Fine, B. M., Jan 1 1998, In : Annals of the New York Academy of Sciences. 841, p. 324-328 5 p.

Research output: Contribution to journalArticle

4 Scopus citations