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Research Output 1995 2019

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Article
2019

A Combination Treatment Strategy for Hemorrhagic Shock in a Rat Model Modulates Autophagy

Chu, X., Schwartz, R., Diamond, M. P. & Raju, R. P., Dec 17 2019, In : Frontiers in Medicine. 6, 281.

Research output: Contribution to journalArticle

Open Access
Hemorrhagic Shock
Autophagy
Wounds and Injuries
Resuscitation
Therapeutics
2 Citations (Scopus)

Deficiency of metabolite sensing receptor HCA2 impairs the salutary effect of niacin in hemorrhagic shock

Subramani, K., Chu, X., Warren, M., Lee, M., Lu, S., Singh, N. & Raju, R. P., Mar 1 2019, In : Biochimica et Biophysica Acta - Molecular Basis of Disease. 1865, 3, p. 688-695 8 p.

Research output: Contribution to journalArticle

Hemorrhagic Shock
Niacin
NAD
Sirtuin 1
Nicotinamide Mononucleotide
1 Citation (Scopus)
Open Access
Cell Aging
Endothelial cells
MicroRNAs
Endothelial Cells
Antioxidants

NLRX1 regulation following acute mitochondrial injury

Chu, X., Wu, S. & Raju, R., Jan 1 2019, In : Frontiers in immunology. 10, OCT, 2431.

Research output: Contribution to journalArticle

Open Access
Innate Immunity
Mitochondria
Wounds and Injuries
Sodium Azide
Homeostasis
2018
1 Citation (Scopus)

Effect of plasma-derived extracellular vesicles on erythrocyte deformability in polymicrobial sepsis

Subramani, K., Raju, S. P., Chu, X., Warren, M., Pandya, C. D., Hoda, MD. N., Fulzele, S. T. & Raju, R. P., Dec 1 2018, In : International Immunopharmacology. 65, p. 244-247 4 p.

Research output: Contribution to journalArticle

Erythrocyte Deformability
Sepsis
Microcirculation
Perfusion
Erythrocytes
2 Citations (Scopus)

Kidney-targeted inhibition of protein kinase C-α ameliorates nephrotoxic nephritis with restoration of mitochondrial dysfunction

Kvirkvelia, N., McMenamin, M., Warren, M., Jadeja, R. N., Kodeboyina, S. K., Sharma, A., Zhi, W., O'Connor, P. M., Raju, R., Lucas, R. & Madaio, M. P., Aug 2018, In : Kidney International. 94, 2, p. 280-291 12 p.

Research output: Contribution to journalArticle

Nephritis
Protein Kinase C
Kidney
Protein C Inhibitor
Mitochondrial Proteins
2017
10 Citations (Scopus)

Mitochondrial dysfunction in rat splenocytes following hemorrhagic shock

Warren, M., Subramani, K., Schwartz, R. B. & Raju, R. P., Oct 1 2017, In : Biochimica et Biophysica Acta - Molecular Basis of Disease. 1863, 10, p. 2526-2533 8 p.

Research output: Contribution to journalArticle

Hemorrhagic Shock
Oxygen Consumption
Wounds and Injuries
Resuscitation
Respiration
7 Citations (Scopus)

Mitochondrial targeting by dichloroacetate improves outcome following hemorrhagic shock

Subramani, K., Lu, S., Warren, M., Chu, X., Flores Toque, H. A., Caldwell, R. W., Diamond, M. P. & Raju, R. P., Dec 1 2017, In : Scientific Reports. 7, 1, 2653.

Research output: Contribution to journalArticle

Hemorrhagic Shock
Resuscitation
AMP-Activated Protein Kinases
Wounds and Injuries
Orphan Drug Production
2016
8 Citations (Scopus)

Alteration of cytokine profile following hemorrhagic shock

Lu, S., Aguilar, A., Subramani, K., Poulose, N., Ayub, A. & Raju, R. P., May 1 2016, In : Cytokine. 81, p. 35-38 4 p.

Research output: Contribution to journalArticle

Hemorrhagic Shock
Cytokines
Wounds and Injuries
Gene expression
Rats
2015
12 Citations (Scopus)

Resveratrol improves survival and prolongs life following hemorrhagic shock

Ayub, A., Poulose, N. & Raju, R. P., Apr 13 2015, In : Molecular Medicine. 21, p. 305-312 8 p.

Research output: Contribution to journalArticle

Hemorrhagic Shock
Resuscitation
Wounds and Injuries
Hemorrhage
resveratrol
2014
27 Citations (Scopus)

A new cecal slurry preparation protocol with improved long-term reproducibility for animal models of sepsis

Starr, M. E., Steele, A. M., Saito, M., Hacker, B. J., Evers, B. M., Saito, H. & Raju, R., Dec 22 2014, In : PloS one. 9, 12, e115705.

Research output: Contribution to journalArticle

sepsis (infection)
reproducibility
laboratory animals
Sepsis
Animals
23 Citations (Scopus)

Resveratrol restores sirtuin 1 (SIRT1) activity and pyruvate dehydrogenase kinase 1 (PDK1) expression after hemorrhagic injury in a rat model

Jian, B., Yang, S., Chaudry, I. H. & Raju, R. P., Jan 1 2014, In : Molecular Medicine. 20, 1, p. 10-16 7 p.

Research output: Contribution to journalArticle

Sirtuin 1
Hemorrhage
Wounds and Injuries
Left Ventricular Function
Mitochondria
1 Citation (Scopus)

Resveratrol suppresses expression of VEGF by human retinal pigment epithelial cells: Potential nutraceutical for Age-related macular degeneration

Nagineni, C. N., Raju, R. P., Nagineni, K. K., Kommineni, V. K., Cherukuri, A., Krishnan Kutty, R., Hooks, J. J. & Detrick, B., Jan 1 2014, In : Aging and Disease. 5, 2, p. 88-100 13 p.

Research output: Contribution to journalArticle

Retinal Pigments
Macular Degeneration
Dietary Supplements
Vascular Endothelial Growth Factors
Epithelial Cells
43 Citations (Scopus)

Resveratrol suppresses expression of VEGF by human retinal pigment epithelial cells: Potential nutraceutical for age-related macular degeneration

Nagineni, C. N., Raju, R. P., Nagineni, K. K., Kommineni, V. K., Cherukuri, A., Kutty, R. K., Hooks, J. J. & Detrick, B., Jan 1 2014, In : Aging and Disease. 5, 2, p. 88-100 13 p.

Research output: Contribution to journalArticle

Retinal Pigments
Macular Degeneration
Dietary Supplements
Vascular Endothelial Growth Factors
Epithelial Cells
2013
4 Citations (Scopus)

Fatigue-Related Gene Networks Identified in CD14+ Cells Isolated From HIV-Infected Patients-Part I: Research Findings

Voss, J. G., Dobra, A., Morse, C., Kovacs, J. A., Danner, R. L., Munson, P. J., Logan, C., Rangel, Z., Adelsberger, J. W., McLaughlin, M., Adams, L. D., Raju, R. & Dalakas, M. C., Feb 12 2013, In : Biological Research For Nursing. 15, 2, p. 137-151 15 p.

Research output: Contribution to journalArticle

Gene Regulatory Networks
Fatigue
HIV
Research
Reverse Transcriptase Inhibitors
3 Citations (Scopus)

Fatigue-Related Gene Networks Identified in CD14+ Cells Isolated From HIV-Infected Patients-Part II: Statistical Analysis

Voss, J. G., Dobra, A., Morse, C., Kovacs, J. A., Raju, R., Danner, R. L., Munson, P. J., Logan, C., Rangel, Z., Adelsberger, J. W., McLaughlin, M., Adams, L. D. & Dalakas, M. C., Feb 12 2013, In : Biological Research For Nursing. 15, 2, p. 152-159 8 p.

Research output: Contribution to journalArticle

Gene Regulatory Networks
Fatigue
HIV
Nursing
Genes
5 Citations (Scopus)

Transforming growth factor-β regulates the expression of anosmin (KAL-1) in human retinal pigment epithelial cells

Raju, R., Jian, B., Hooks, J. J. & Nagineni, C. N., Mar 1 2013, In : Cytokine. 61, 3, p. 724-727 4 p.

Research output: Contribution to journalArticle

Kallmann Syndrome
Retinal Pigments
Transforming Growth Factors
Epithelial Cells
Heparin
2012
21 Citations (Scopus)

Provision of an explanation for the inefficacy of immunotherapy in sporadic inclusion body myositis: Quantitative assessment of inflammation and β-amyloid in the muscle

Zschüntzsch, J., Voss, J., Creus, K., Sehmisch, S., Raju, R., Dalakas, M. C. & Schmidt, J., Dec 1 2012, In : Arthritis and Rheumatism. 64, 12, p. 4094-4103 10 p.

Research output: Contribution to journalArticle

Inclusion Body Myositis
Amyloid
Immunotherapy
Prednisone
Intravenous Immunoglobulins
44 Citations (Scopus)

Resveratrol improves cardiac contractility following trauma-hemorrhage by modulating Sirt1

Jian, B., Yang, S., Chaudry, I. H. & Raju, R., Feb 1 2012, In : Molecular Medicine. 18, 2, p. 209-214 6 p.

Research output: Contribution to journalArticle

Hemorrhage
Wounds and Injuries
Resuscitation
Cytochromes
Adenosine Triphosphate
2011
18 Citations (Scopus)

Aging influences cardiac mitochondrial gene expression and cardiovascular function following hemorrhage injury

Jian, B., Yang, S., Chen, D., Zou, L., Chatham, J. C., Chaudry, I. & Raju, R., May 1 2011, In : Molecular Medicine. 17, 5-6, p. 542-549 8 p.

Research output: Contribution to journalArticle

Mitochondrial Genes
Hemorrhage
Gene Expression
Wounds and Injuries
Cell Aging
18 Citations (Scopus)

Influence of aging and hemorrhage injury on Sirt1 expression: Possible role of myc-Sirt1 regulation in mitochondrial function

Jian, B., Yang, S., Chen, D., Chaudry, I. & Raju, R., Nov 1 2011, In : Biochimica et Biophysica Acta - Molecular Basis of Disease. 1812, 11, p. 1446-1451 6 p.

Research output: Contribution to journalArticle

Hemorrhage
Wounds and Injuries
Organelle Biogenesis
Mitochondrial Genes
Cytochromes c
2010
24 Citations (Scopus)

Effect of estrogen on mitochondrial function and intracellular stress markers in rat liver and kidney following trauma-hemorrhagic shock and prolonged hypotension

Kozlov, A. V., Catharina Duvigneau, J., Hyatt, T. C., Raju, R., Behling, T., Hartl, R. T., Staniek, K., Miller, I., Gregor, W., Redl, H. & Chaudry, I. H., Jan 1 2010, In : Molecular Medicine. 16, 7-8, p. 254-261 8 p.

Research output: Contribution to journalArticle

Hemorrhagic Shock
Hypotension
Estrogens
Endoplasmic Reticulum Stress
Kidney
21 Citations (Scopus)

Hypoxia-induced alteration of mitochondrial genes in cardiomyocytes: Role of Bnip3 and Pdk1

Jian, B., Wang, D., Chen, D., Voss, J., Chaudry, I. & Raju, R., Aug 2010, In : Shock. 34, 2, p. 169-175 7 p.

Research output: Contribution to journalArticle

Mitochondrial Genes
Cardiac Myocytes
Mitochondrial DNA
Genes
Oxygen
2009
19 Citations (Scopus)

Anosmin-1 involved in neuronal cell migration is hypoxia inducible and cancer regulated

Jian, B., Nagineni, C. N., Meleth, S., Grizzle, W., Bland, K., Chaudry, I. & Raju, R., Nov 15 2009, In : Cell Cycle. 8, 22, p. 3770-3776 7 p.

Research output: Contribution to journalArticle

Cell Movement
Colonic Neoplasms
Gene Expression
Neoplasms
Complementary DNA
194 Citations (Scopus)

Placebo-controlled trial of rituximab in IgM anti-myelin-associated glycoprotein antibody demyelinating neuropathy

Dalakas, M. C., Rakocevic, G., Salajegheh, M., Dambrosia, J. M., Hahn, A. F., Raju, R. P. & McElroy, B., Mar 1 2009, In : Annals of Neurology. 65, 3, p. 286-293 8 p.

Research output: Contribution to journalArticle

Myelin-Associated Glycoprotein
Placebos
Antibodies
Polyneuropathies
B-Lymphocytes
16 Citations (Scopus)

Suppression of activation and costimulatory signaling in splenic CD4 + T cells after trauma-hemorrhage reduces t-cell function: A mechanism of post-traumatic immune suppression

Hsieh, C. H., Hsu, J. T., Hsieh, Y. C., Frink, M., Raju, R., Hubbard, W. J., Bland, K. I. & Chaudry, I. H., Jan 1 2009, In : American Journal of Pathology. 175, 4, p. 1504-1514 11 p.

Research output: Contribution to journalArticle

Hemorrhage
T-Lymphocytes
Wounds and Injuries
CTLA-4 Antigen
Ovalbumin
2008
37 Citations (Scopus)

Activation of endoplasmic reticulum stress response following trauma-hemorrhage

Jian, B., Hsieh, C. H., Chen, J., Choudhry, M., Bland, K., Chaudry, I. & Raju, R., Nov 1 2008, In : Biochimica et Biophysica Acta - Molecular Basis of Disease. 1782, 11, p. 621-626 6 p.

Research output: Contribution to journalArticle

Endoplasmic Reticulum Stress
Hemorrhage
Wounds and Injuries
Liver
Apoptosis
10 Citations (Scopus)

A focused microarray to study human mitochondrial and nuclear gene expression

Voss, J. G., Raju, R. P., Logun, C., Danner, R. L., Munson, P. J., Rangel, Z. & Dalakas, M. C., Apr 1 2008, In : Biological Research For Nursing. 9, 4, p. 272-279 8 p.

Research output: Contribution to journalArticle

Mitochondrial Genes
Oligonucleotide Array Sequence Analysis
Gene Expression
Mitochondrial Genome
Interferon-gamma
27 Citations (Scopus)

Flutamide protects against trauma-hemorrhage-induced liver injury via attenuation of the inflammatory response, oxidative stress, and apopotosis

Kan, W. H., Hsieh, C. H., Schwacha, M. G., Choudhry, M. A., Raju, R., Bland, K. I. & Chaudry, I. H., Aug 1 2008, In : Journal of Applied Physiology. 105, 2, p. 595-602 8 p.

Research output: Contribution to journalArticle

Flutamide
Oxidative Stress
Hemorrhage
Liver
Wounds and Injuries
35 Citations (Scopus)

Selective inhibition of iNOS attenuates trauma-hemorrhage/resuscitation- induced hepatic injury

Kan, W. H., Hsu, J. T., Schwacha, M. G., Choudhry, M. A., Raju, R., Bland, K. I. & Chaudry, I. H., Oct 1 2008, In : Journal of Applied Physiology. 105, 4, p. 1076-1082 7 p.

Research output: Contribution to journalArticle

Resuscitation
Hemorrhage
Liver
Wounds and Injuries
NG-Nitroarginine Methyl Ester
2007
5 Citations (Scopus)

Absence of upregulated genes associated with protein accumulations in desmin myopathy

Raju, R. & Dalakas, M. C., Mar 1 2007, In : Muscle and Nerve. 35, 3, p. 386-388 3 p.

Research output: Contribution to journalArticle

Desmin
Muscular Diseases
Genes
Proteins
Gelsolin
54 Citations (Scopus)

Immune response modulation by curcumin in a latex allergy model

Kurup, V. P., Barrios, C. S., Raju, R., Johnson, B. D., Levy, M. B. & Fink, J. N., Mar 1 2007, In : Clinical and Molecular Allergy. 5, 1.

Research output: Contribution to journalArticle

Latex Hypersensitivity
Curcumin
Latex
Allergens
Pneumonia
60 Citations (Scopus)

Inclusion body myositis with human immunodeficiency virus infection: Four cases with clonal expansion of viral-specific T cells

Dalakas, M. C., Rakocevic, G., Shatunov, A., Goldfarb, L., Raju, R. P. & Salajegheh, M., May 1 2007, In : Annals of Neurology. 61, 5, p. 466-475 10 p.

Research output: Contribution to journalArticle

Inclusion Body Myositis
Virus Diseases
HIV
T-Lymphocytes
Muscles
39 Citations (Scopus)

T cell receptor profiling in muscle and blood lymphocytes in sporadic inclusion body myositis

Salajegheh, M., Rakocevic, G., Raju, R. P., Shatunov, A., Goldfarb, L. G. & Dalakas, M. C., Jan 1 2007, In : Neurology. 69, 17, p. 1672-1679 8 p.

Research output: Contribution to journalArticle

Inclusion Body Myositis
T-Cell Antigen Receptor
Lymphocytes
Muscles
T-Lymphocytes
16 Citations (Scopus)

Upregulation of thrombospondin-1(TSP-1) and its binding partners, CD36 and CD47, in sporadic inclusion body myositis

Salajegheh, M., Raju, R., Schmidt, J. & Dalakas, M. C., Jul 1 2007, In : Journal of Neuroimmunology. 187, 1-2, p. 166-174 9 p.

Research output: Contribution to journalArticle

Inclusion Body Myositis
Thrombospondin 1
Myoblasts
Up-Regulation
Inflammation
2006
90 Citations (Scopus)

Autoimmunity to GABAA-receptor-associated protein in stiff-person syndrome

Raju, R., Rakocevic, G., Chen, Z., Hoehn, G., Semino-Mora, C., Shi, W., Olsen, R. & Dalakas, M. C., Dec 1 2006, In : Brain. 129, 12, p. 3270-3276 7 p.

Research output: Contribution to journalArticle

Stiff-Person Syndrome
GABA-A Receptors
Autoimmunity
Proteins
Glutamate Decarboxylase
56 Citations (Scopus)

Stiff person syndrome with cerebellar disease and high-titer anti-GAD antibodies

Rakocevic, G., Raju, R. P., Semino-Mora, C. & Dalakas, M. C., Sep 1 2006, In : Neurology. 67, 6, p. 1068-1070 3 p.

Research output: Contribution to journalArticle

Stiff-Person Syndrome
Cerebellar Diseases
Anti-Idiotypic Antibodies
Gait Ataxia
Aminobutyrates
2005
111 Citations (Scopus)

Analysis of GAD65 autoantibodies in Stiff-Person syndrome patients

Raju, R., Foote, J., Banga, J. P., Hall, T. R., Padoa, C. J., Dalakas, M. C., Ortqvist, E. & Hampe, C. S., Dec 1 2005, In : Journal of Immunology. 175, 11, p. 7755-7762 8 p.

Research output: Contribution to journalArticle

Stiff-Person Syndrome
Autoantibodies
Epitopes
Cerebrospinal Fluid
Serum
122 Citations (Scopus)
Myositis
Dermatomyositis
Intravenous Immunoglobulins
Transcriptome
Muscles
8 Citations (Scopus)

Profile of gene expression in a murine model of allergic bronchopulmonary aspergillosis

Kurup, V. P., Raju, R. & Manickam, P., Jul 1 2005, In : Infection and Immunity. 73, 7, p. 4381-4384 4 p.

Research output: Contribution to journalArticle

Allergic Bronchopulmonary Aspergillosis
Transcriptome
Genes
Aspergillus
Chemokines
2004
82 Citations (Scopus)

Anti-glutamic acid decarboxylase antibodies in the serum and cerebrospinal fluid of patients with stiff-person syndrome: Correlation with clinical severity

Rakocevic, G., Raju, R. & Dalakas, M. C., Jun 1 2004, In : Archives of Neurology. 61, 6, p. 902-904 3 p.

Research output: Contribution to journalArticle

Stiff-Person Syndrome
Glutamate Decarboxylase
Cerebrospinal Fluid
Antibodies
Serum
2003
8 Citations (Scopus)

Alloimmune induction of endothelial cell-derived interferon-γ-inducible chemokines

Raju, R., Malloy, A., Shah, T., Smith, R., Oaks, M. & Hosenpud, J. D., Apr 15 2003, In : Transplantation. 75, 7, p. 1072-1074 3 p.

Research output: Contribution to journalArticle

Chemokines
Interferons
Endothelial Cells
Blood Cells
Coculture Techniques

A T-linker strategy for modification and directional cloning of PCR products.

Horton, R. M., Raju, R. P. & Conti-Fine, B. M., Jan 1 2003, In : Methods in molecular biology (Clifton, N.J.). 226, p. 475-484 10 p.

Research output: Contribution to journalArticle

DNA Primers
Molecular Cloning
Organism Cloning
Amino Acid Sequence
Polymerase Chain Reaction
15 Citations (Scopus)

Evidence of a diverse T cell receptor repertoire for acetylcholine receptor, the autoantigen of myasthenia gravis

Infante, A. J., Baillargeon, J., Kraig, E., Lott, L., Jackson, C., Hämmerling, G. J., Raju, R. & David, C., Sep 2003, In : Journal of Autoimmunity. 21, 2, p. 167-174 8 p.

Research output: Contribution to journalArticle

Myasthenia Gravis
Autoantigens
Cholinergic Receptors
T-Cell Antigen Receptor
Hybridomas
57 Citations (Scopus)

Expression of IFN-γ-inducible chemokines in inclusion body myositis

Raju, R., Vasconcelos, O., Granger, R. & Dalakas, M. C., Aug 2003, In : Journal of Neuroimmunology. 141, 1-2, p. 125-131 7 p.

Research output: Contribution to journalArticle

Inclusion Body Myositis
Chemokines
T-Lymphocytes
Skeletal Muscle Fibers
Chemokine CXCL9
2002
4 Citations (Scopus)

Cryptic determinants and promiscuous sequences on human acetylcholine receptor: HLA-dependent dichotomy in T-cell function

Raju, R., Marietta, E., Vinasco, J., Conti-Fine, B. M., Infante, A. J. & David, C. S., Apr 23 2002, In : Human Immunology. 63, 4, p. 237-247 11 p.

Research output: Contribution to journalArticle

Cholinergic Receptors
Transgenic Mice
T-Lymphocytes
Myasthenia Gravis
Autoimmune Experimental Myasthenia Gravis
38 Citations (Scopus)

GNE mutations in an American family with quadriceps-sparing IBM and lack of mutations in s-IBM

Vasconcelos, O. M., Raju, R. & Dalakas, M. C., Dec 10 2002, In : Neurology. 59, 11, p. 1776-1779 4 p.

Research output: Contribution to journalArticle

Mutation
Quadriceps Muscle
Missense Mutation
Disease Progression
Biopsy
18 Citations (Scopus)

Modulation of insulitis and type 1 diabetes by transgenic HLA-DR3 and DQ8 in NOD mice lacking endogenous MHC class II

Kudva, Y. C., Rajagopalan, G., Raju, R., Abraham, R. S., Smart, M., Hanson, J. & David, C. S., Nov 1 2002, In : Human Immunology. 63, 11, p. 987-999 13 p.

Research output: Contribution to journalArticle

Inbred NOD Mouse
HLA Antigens
Type 1 Diabetes Mellitus
Cyclophosphamide
Transgenic Mice
2001
15 Citations (Scopus)

Acetylcholine receptor peptide recognition in HLA DR3-transgenic mice: In vivo responses correlate with MHC-peptide binding

Raju, R., Spack, E. G. & David, C. S., Jul 15 2001, In : Journal of Immunology. 167, 2, p. 1118-1124 7 p.

Research output: Contribution to journalArticle

HLA-DR3 Antigen
Cholinergic Receptors
Transgenic Mice
Myasthenia Gravis
Peptides
1998
4 Citations (Scopus)

Acetylcholine receptor-specific CD4+ T cells in myasthenia gravis patients have individual, but restricted TCR Vβ usage

Raju, R., Navaneetham, D., Protti, M. P., Horton, R. M., Hoppe, B. L., Howard, J. & Conti-Fine, B. M., Jan 1 1998, In : Annals of the New York Academy of Sciences. 841, p. 324-328 5 p.

Research output: Contribution to journalArticle

T-cells
Cholinergic Receptors