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Franklin Chi Meng Tay

Department Chair

  • 34761 Citations
  • 96 h-Index
1984 …2019
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Research Output 1984 2019

2019
3 Citations (Scopus)

A potential therapeutic target for regulating osteoporosis via suppression of osteoclast differentiation

Sun, Q., Zhang, B., Zhu, W., Wei, W., Ma, J. & Tay, F. C. M., Mar 2019, In : Journal of Dentistry. 82, p. 91-97 7 p.

Research output: Contribution to journal › Article

Osteoclasts
Osteogenesis
Osteoporosis
MafB Transcription Factor
Computational Biology
3 Citations (Scopus)

Bimodal antibacterial system based on quaternary ammonium silane-coupled core-shell hollow mesoporous silica

Bai, Y. M., Mao, J., Li, D. X., Luo, X. J., Chen, J., Tay, F. C. M. & Niu, L. N., Feb 1 2019, In : Acta biomaterialia. 85, p. 229-240 12 p.

Research output: Contribution to journal › Article

Silanes
Metronidazole
Ammonium Compounds
Silicon Dioxide
Antibiotics
1 Citation (Scopus)

Bioactive tri/dicalcium silicate cements for treatment of pulpal and periapical tissues

Primus, C. M., Tay, F. C. M. & Niu, L. N., Sep 15 2019, In : Acta biomaterialia. 96, p. 35-54 20 p.

Research output: Contribution to journal › Review article

Silicate Cement
Periapical Tissue
Dental Materials
Dentists
Silicates

Carbodiimide inactivation of matrix metalloproteinases in radicular dentine

Comba, A., Scotti, N., Mazzoni, A., Maravic, T., Ribeiro Cunha, S., Michelotto Tempesta, R., Carossa, M., Pashley, D. H., Tay, F. C. M. & Breschi, L., Mar 2019, In : Journal of Dentistry. 82, p. 56-62 7 p.

Research output: Contribution to journal › Article

Carbodiimides
Dentin
Matrix Metalloproteinases
Ethyldimethylaminopropyl Carbodiimide
Artificial Saliva
2 Citations (Scopus)

Chitosan-Based Extrafibrillar Demineralization for Dentin Bonding

Gu, L. S., Cai, X., Guo, J. M., Pashley, D. H., Breschi, L., Xu, H. H. K., Wang, X. Y., Tay, F. C. M. & Niu, L. N., Feb 1 2019, In : Journal of Dental Research. 98, 2, p. 186-193 8 p.

Research output: Contribution to journal › Article

Chitosan
Dentin
Minerals
Collagen
Analysis of Variance
4 Citations (Scopus)

Contribution of biomimetic collagen-ligand interaction to intrafibrillar mineralization

Song, Q., Jiao, K., Tonggu, L., Wang, L. G., Zhang, S. L., Yang, Y. D., Zhang, L., Bian, J. H., Hao, D. X., Wang, C. Y., Ma, Y. X., Arola, D. D., Breschi, L., Chen, J. H., Tay, F. C. M. & Niu, L. N., Mar 29 2019, In : Science Advances. 5, 3, eaav9075.

Research output: Contribution to journal › Article

Open Access
biomimetics
collagens
ligands
interactions
calcification

Development of a new class of self-healing and therapeutic dental resins

Wu, J., Xie, X., Zhou, H., Tay, F. C. M., Weir, M. D., Melo, M. A. S., Oates, T. W., Zhang, N., Zhang, Q. & Xu, H. H. K., May 2019, In : Polymer Degradation and Stability. 163, p. 87-99 13 p.

Research output: Contribution to journal › Review article

Open Access
Synthetic Resins
healing
Biofilms
resins
Restoration

Effect of benzalkonium chloride on dentin bond strength and endogenous enzymatic activity

Comba, A., Maravic, T., Valente, L., Girlando, M., Cunha, S. R., Checchi, V., Salgarello, S., Tay, F. R., Scotti, N., Breschi, L. & Mazzoni, A., Jun 2019, In : Journal of Dentistry. 85, p. 25-32 8 p.

Research output: Contribution to journal › Article

Benzalkonium Compounds
Dentin
Adhesives
Methacrylates
Gelatin
2 Citations (Scopus)

Evaluation of several instrumentation techniques and irrigation methods on the percentage of untouched canal wall and accumulated dentine debris in C-shaped canals

Zhao, Y., Fan, W., Xu, T., Tay, F. C. M., Gutmann, J. L. & Fan, B., Jan 1 2019, In : International Endodontic Journal. 52, 9, p. 1354-1365 12 p.

Research output: Contribution to journal › Article

Dentin
Syringes
Ultrasonics
Needles
Switzerland

Insights into the August 2019 Issue of the Journal of Endodontics

Azarpazhooh, A., Diogenes, A. R., Fouad, A. F., Glickman, G. N., Kang, M. K., Kishen, A., Levin, L., Roda, R. S., Sedgley, C. M., Tay, F. C. M. & Hargreaves, K. M., Aug 2019, In : Journal of Endodontics. 45, 8, p. 963-964 2 p.

Research output: Contribution to journal › Editorial

Endodontics

Insights into the July 2019 Issue of the Journal of Endodontics

Azarpazhooh, A., Kishen, A., Tay, F. R., Diogenes, A. R., Hargreaves, K. M., Fouad, A. F., Glickman, G. N., Kang, M. K., Levin, L., Roda, R. S. & Sedgley, C. M., Jul 2019, In : Journal of Endodontics. 45, 7, p. 829-830 2 p.

Research output: Contribution to journal › Editorial

Endodontics

Isocyanate-terminated urethane-based dental adhesive bridges dentinal matrix collagen with adhesive resin

Xu, R., Yu, F., Huang, L., Zhou, W., Wang, Y., Wang, F., Sun, X., Chang, G., Fang, M., Zhang, L., Li, F., Tay, F. C. M., Niu, L. & Chen, J., Jan 1 2019, In : Acta biomaterialia. 83, p. 140-152 13 p.

Research output: Contribution to journal › Article

Dental Cements
Isocyanates
Methacrylates
Urethane
Collagen

Management of Large Radicular Lesions Using Decompression: A Case Series and Review of the Literature

Tian, F., Bergeron, B. E., Kalathingal, S. M., Morris, M., Wang, X. Y., Niu, L. N. & Tay, F. C. M., May 2019, In : Journal of endodontics. 45, 5, p. 651-659 9 p.

Research output: Contribution to journal › Article

Decompression
Needles
Dental Pulp Cavity
Gutta-Percha
Endodontics

Micro–computed Tomographic Evaluation of the Prevalence, Distribution, and Morphologic Features of Accessory Canals in Chinese Permanent Teeth

Xu, T., Fan, W., Tay, F. R. & Fan, B., Aug 2019, In : Journal of Endodontics. 45, 8, p. 994-999 6 p.

Research output: Contribution to journal › Article

Tooth
Dental Pulp Cavity
Bicuspid
Population
Incidence
5 Citations (Scopus)

MMP-8-Responsive Polyethylene Glycol Hydrogel for Intraoral Drug Delivery

Guo, J., Sun, H., Lei, W., Tang, Y., Hong, S., Yang, H., Tay, F. C. M. & Huang, C., May 1 2019, In : Journal of Dental Research. 98, 5, p. 564-571 8 p.

Research output: Contribution to journal › Article

Matrix Metalloproteinase 8
Hydrogel
Pharmaceutical Preparations
Drug Delivery Systems
Mouth Diseases
1 Citation (Scopus)

Novel bioactive root canal sealer with antibiofilm and remineralization properties

Baras, B. H., Wang, S., Melo, M. A. S., Tay, F., Fouad, A. F., Arola, D. D., Weir, M. D. & Xu, H. H. K., Apr 2019, In : Journal of Dentistry. 83, p. 67-76 10 p.

Research output: Contribution to journal › Article

Methacrylates
Dental Pulp Cavity
Biofilms
Nanoparticles
Endodontics
8 Citations (Scopus)

Novel Biomedical Applications of Crosslinked Collagen

Gu, L., Shan, T., Ma, Y. X., Tay, F. C. M. & Niu, L., May 1 2019, In : Trends in Biotechnology. 37, 5, p. 464-491 28 p.

Research output: Contribution to journal › Review article

Collagen
Biopolymers
Crosslinking
Enzyme Stability
Mechanical stability
1 Citation (Scopus)

Novel multifunctional nanocomposite for root caries restorations to inhibit periodontitis-related pathogens

Xiao, S., Wang, H., Liang, K., Tay, F. C. M., Weir, M. D., Melo, M. A. S., Wang, L., Wu, Y., Oates, T. W., Ding, Y. & Xu, H. H. K., Feb 2019, In : Journal of Dentistry. 81, p. 17-26 10 p.

Research output: Contribution to journal › Article

Root Caries
Nanocomposites
Methacrylates
Periodontitis
Biofilms

Poly(amido amine) and rechargeable adhesive containing calcium phosphate nanoparticles for long-term dentin remineralization

Liang, K., Gao, Y., Xiao, S., Tay, F. C. M., Weir, M. D., Zhou, X., Oates, T. W., Zhou, C., Li, J. & Xu, H. H. K., Jun 2019, In : Journal of Dentistry. 85, p. 47-56 10 p.

Research output: Contribution to journal › Article

Dentin
Adhesives
Nanoparticles
Amines
Ions

Polymer conjugation optimizes EDTA as a calcium-chelating agent that exclusively removes extrafibrillar minerals from mineralized collagen

Guo, J. M., Makvandi, P., Wei, C. C., Chen, J. H., Xu, H. K., Breschi, L., Pashley, D. H., Huang, C., Niu, L. N. & Tay, F. C. M., May 2019, In : Acta biomaterialia. 90, p. 424-440 17 p.

Research output: Contribution to journal › Article

Ethylenediaminetetraacetic acid
Dentin
Chelation
Glycols
Chitosan
2 Citations (Scopus)

Protection against HeMA-induced mitochondrial injury in vitro by Nrf2 activation

Jiao, Y., Niu, T., Liu, H., Tay, F. C. M. & Chen, J. H., Jan 1 2019, In : Oxidative medicine and cellular longevity. 2019, 3501059.

Research output: Contribution to journal › Article

Open Access
Chemical activation
Synthetic Resins
Wounds and Injuries
Explosive well stimulation
Nuclear Respiratory Factor 1
3 Citations (Scopus)

Pulpotomy for carious pulp exposures in permanent teeth: A systematic review and meta-analysis

Li, Y., Sui, B., Dahl, C., Bergeron, B., Shipman, P., Niu, L., Chen, J. & Tay, F. R., May 2019, In : Journal of Dentistry. 84, p. 1-8 8 p.

Research output: Contribution to journal › Review article

Pulpotomy
Meta-Analysis
Tooth
Pulpitis
Cost-Benefit Analysis
8 Citations (Scopus)

Recent progress in the industrial and biomedical applications of tragacanth gum: A review

Nazarzadeh Zare, E., Makvandi, P. & Tay, F. C. M., May 15 2019, In : Carbohydrate Polymers. 212, p. 450-467 18 p.

Research output: Contribution to journal › Review article

Tragacanth
Natural polymers
Biodegradability
Cytotoxicity
Polysaccharides

Self-healing adhesive with antibacterial activity in water-aging for 12 months

Wu, J., Zhou, C., Ruan, J., Weir, M. D., Tay, F. C. M., Sun, J., Melo, M. A. S., Oates, T. W., Chang, X. & Xu, H. H. K., Aug 2019, In : Dental Materials. 35, 8, p. 1104-1116 13 p.

Research output: Contribution to journal › Article

Adhesives
Methacrylates
Dentin
Aging of materials
Calcium phosphate
3 Citations (Scopus)

Surface treatments on titanium implants via nanostructured ceria for antibacterial and anti-inflammatory capabilities

Li, X., Qi, M., Sun, X., Weir, M. D., Tay, F. C. M., Oates, T. W., Dong, B., Zhou, Y., Wang, L. & Xu, H. H. K., Aug 1 2019, In : Acta biomaterialia. 94, p. 627-643 17 p.

Research output: Contribution to journal › Article

Cerium compounds
Titanium
Surface treatment
Anti-Inflammatory Agents
Peri-Implantitis
1 Citation (Scopus)

The effect of food medium on the wear behaviour of veneering porcelain: An in vitro study using the three-body abrasion mode

Zhang, H., Sun, Y., Guo, J., Meng, M., He, L., Tay, F. C. M. & Zhang, S., Apr 2019, In : Journal of Dentistry. 83, p. 87-94 8 p.

Research output: Contribution to journal › Article

Dental Porcelain
Food
Apium graveolens
Metals
Mastication
1 Citation (Scopus)

Topical application of phenytoin or nifedipine-loaded PLGA microspheres promotes periodontal regeneration in vivo

Zhao, X. H., Tay, F. R., Fang, Y. J., Meng, L. Y. & Bian, Z., Jan 2019, In : Archives of Oral Biology. 97, p. 42-51 10 p.

Research output: Contribution to journal › Article

glycolic acid
Phenytoin
Nifedipine
Microspheres
Regeneration
1 Citation (Scopus)

Vital pulp therapy: histopathology and histobacteriology-based guidelines to treat teeth with deep caries and pulp exposure

Ricucci, D., Siqueira, J. F., Li, Y. & Tay, F. C. M., Jul 1 2019, In : Journal of Dentistry. 86, p. 41-52 12 p.

Research output: Contribution to journal › Article

Tooth
Guidelines
Dentin
Pulpotomy
Therapeutics
2018

Air entrapment in demineralized dentin adversely affects bonding

Li, Y., Fang, M., Yu, F., Niu, L., Tay, F. C. M. & Chen, J., Jan 1 2018, In : Journal of Adhesive Dentistry. 20, 3, p. 249-259 11 p.

Research output: Contribution to journal › Article

Dentin
Air
Pressure
Adhesives
Control Groups
8 Citations (Scopus)

Antibacterial and remineralizing orthodontic adhesive containing quaternary ammonium resin monomer and amorphous calcium phosphate nanoparticles

Liu, Y., Zhang, L., Niu, L. N., Yu, T., Xu, H. H. K., Weir, M. D., Oates, T. W., Tay, F. C. M. & Chen, J. H., May 1 2018, In : Journal of Dentistry. 72, p. 53-63 11 p.

Research output: Contribution to journal › Article

Dental Cements
Dental Enamel
Ammonium Compounds
Adhesives
Nanoparticles
3 Citations (Scopus)

Antibacterial efficacy of an endodontic sonic-powered irrigation system: An in vitro study

Zeng, C., Willison, J., Meghil, M. M., Bergeron, B. E., Cutler, C. W., Tay, F. R., Niu, L. & Ma, J., Aug 2018, In : Journal of Dentistry. 75, p. 105-112 8 p.

Research output: Contribution to journal › Article

Endodontics
Syringes
Tooth
Needles
Bacteria
3 Citations (Scopus)

Anti-biofilm efficacy of root canal irrigants against in-situ Enterococcus faecalis biofilms in root canals, isthmuses and dentinal tubules

Ye, W. H., Fan, B., Purcell, W., Meghil, M. M., Cutler, C. W., Bergeron, B. E., Ma, J. Z., Tay, F. R. & Niu, L. N., Dec 2018, In : Journal of Dentistry. 79, p. 68-76 9 p.

Research output: Contribution to journal › Article

Root Canal Irrigants
Enterococcus faecalis
Dental Pulp Cavity
Biofilms
Bacteria
2 Citations (Scopus)

Antimicrobial efficacy of an apical negative pressure root canal irrigation system against intracanal microorganisms

Zeng, C., Meghil, M. M., Miller, M., Gou, Y., Cutler, C. W., Bergeron, B. E., Niu, L., Ma, J. & Tay, F. R., May 2018, In : Journal of Dentistry. 72, p. 71-75 5 p.

Research output: Contribution to journal › Article

Dental Pulp Cavity
Pressure
Tooth
Stem Cells
Periapical Periodontitis
2 Citations (Scopus)

Association between bruxism and symptomatic gastroesophageal reflux disease: A case-control study

Li, Y., Yu, F., Niu, L., Long, Y., Tay, F. C. M. & Chen, J., Oct 2018, In : Journal of Dentistry. 77, p. 51-58 8 p.

Research output: Contribution to journal › Article

Bruxism
Gastroesophageal Reflux
Case-Control Studies
Odds Ratio
Confidence Intervals

Biochemical and immunohistochemical identification of MMP-7 in human dentin

Mazzoni, A., Maravić, T., Tezvergil-Mutluay, A., Tjäderhane, L., Scaffa, P. M. C., Seseogullari-Dirihan, R., Bavelloni, A., Gobbi, P., Pashley, D. H., Tay, F. R. & Breschi, L., Dec 2018, In : Journal of Dentistry. 79, p. 90-95 6 p.

Research output: Contribution to journal › Article

Matrix Metalloproteinase 7
Dentin
Matrix Metalloproteinases
Microspheres
Immunoassay
9 Citations (Scopus)

Biological activities and potential oral applications of N-acetylcysteine: Progress and prospects

Pei, Y., Liu, H., Yang, Y., Yang, Y., Jiao, Y., Tay, F. C. M. & Chen, J., Jan 1 2018, In : Oxidative medicine and cellular longevity. 2018, 2835787.

Research output: Contribution to journal › Review article

Acetylcysteine
Bioactivity
Antimutagenic Agents
Anticarcinogenic Agents
Expectorants
4 Citations (Scopus)

Changes in the radicular pulp-dentine complex in healthy intact teeth and in response to deep caries or restorations: A histological and histobacteriological study

Ricucci, D., Loghin, S., Niu, L. N. & Tay, F. C. M., Jun 1 2018, In : Journal of Dentistry. 73, p. 76-90 15 p.

Research output: Contribution to journal › Article

Dentin
Tooth
Dental Pulp Capping
Odontoblasts
Connective Tissue
2 Citations (Scopus)

Contribution of Mitophagy to Cell-Mediated Mineralization: Revisiting a 50-Year-Old Conundrum

Pei, D. D., Sun, J. L., Zhu, C. H., Tian, F., Jiao, K., Anderson, M. R., Yiu, C., Huang, C., Jin, C. X., Bergeron, B. E., Chen, J. H., Tay, F. C. M. & Niu, L. N., Oct 2018, In : Advanced Science. 5, 10, 1800873.

Research output: Contribution to journal › Article

Mitochondrial Degradation
calcium phosphates
Calcium phosphate
Mitochondria
mitochondria
7 Citations (Scopus)

Cross-linking effect on dentin bond strength and MMPs activity

Mazzoni, A., Angeloni, V., Comba, A., Maravic, T., Cadenaro, M., Tezvergil-Mutluay, A., Pashley, D. H., Tay, F. C. M. & Breschi, L., Feb 1 2018, In : Dental Materials. 34, 2, p. 288-295 8 p.

Research output: Contribution to journal › Article

Dentin
Matrix Metalloproteinases
Adhesives
Gelatinases
Aging of materials
34 Citations (Scopus)

Dentin bonding systems: From dentin collagen structure to bond preservation and clinical applications

Breschi, L., Maravic, T., Cunha, S. R., Comba, A., Cadenaro, M., Tjäderhane, L., Pashley, D. H., Tay, F. C. M. & Mazzoni, A., Jan 1 2018, In : Dental Materials. 34, 1, p. 78-96 19 p.

Research output: Contribution to journal › Review article

Dentin
Collagen
Degradation
Adhesives
Dental materials
1 Citation (Scopus)

Effect of simulated intraosseous sinusoidal pressure on NaOCl extrusion

Cai, X., Wang, X. Y., Santarcangelo, F., Schoeffel, G. J., Bergeron, B. E., Tay, F. C. M. & Niu, L. N., Nov 2018, In : Journal of Dentistry. 78, p. 46-50 5 p.

Research output: Contribution to journal › Article

Pressure
Needles
Atmospheric Pressure
Dental Pulp Cavity
Analysis of Variance
1 Citation (Scopus)

Experimental use of an acrolein-based primer as collagen cross-linker for dentine bonding

Maravic, T., Breschi, L., Comba, A., Cunha, S. R., Angeloni, V., Nucci, C., Hebling, J., Pashley, D., Tay, F. & Mazzoni, A., Jan 2018, In : Journal of Dentistry. 68, p. 85-90 6 p.

Research output: Contribution to journal › Article

Acrolein
Dentin
Collagen
Matrix Metalloproteinases
Adhesives
1 Citation (Scopus)

Hollow mesoporous zirconia delivery system for biomineralization precursors

Huang, X. Q., Yang, H. Y., Luo, T., Huang, C., Tay, F. C. M. & Niu, L. N., Feb 2018, In : Acta biomaterialia. 67, p. 366-377 12 p.

Research output: Contribution to journal › Article

Nanocapsules
Biomineralization
Tissue Engineering
Zirconia
Bone
1 Citation (Scopus)

Intrafibrillar silicified collagen scaffold promotes in-situ bone regeneration by activating the monocyte p38 signaling pathway

Sun, J. L., Jiao, K., Song, Q., Ma, C. F., Ma, C., Tay, F. C. M., Niu, L. N. & Chen, J. H., Feb 1 2018, In : Acta biomaterialia. 67, p. 354-365 12 p.

Research output: Contribution to journal › Article

Bone Regeneration
Scaffolds (biology)
Collagen
Scaffolds
Monocytes
1 Citation (Scopus)

Mechanism of bioactive molecular extraction from mineralized dentin by calcium hydroxide and tricalcium silicate cement

Huang, X. Q., Camba, J., Gu, L. S., Bergeron, B. E., Ricucci, D., Pashley, D. H., Tay, F. C. M. & Niu, L. N., Feb 1 2018, In : Dental Materials. 34, 2, p. 317-330 14 p.

Research output: Contribution to journal › Article

Silicate Cement
Calcium Hydroxide
Hydrated lime
Dentin
Collagen
3 Citations (Scopus)

Optimizing resin-dentin bond stability using a bioactive adhesive with concomitant antibacterial properties and anti-proteolytic activities

Gou, Y. P., Meghil, M. M., Pucci, C. R., Breschi, L., Pashley, D. H., Cutler, C. W., Niu, L. N., Li, J. Y. & Tay, F. C. M., Jul 15 2018, In : Acta biomaterialia. 75, p. 171-182 12 p.

Research output: Contribution to journal › Article

Dentin
Silanes
Adhesives
Ammonium Compounds
Resins
5 Citations (Scopus)

Protein-repelling adhesive resin containing calcium phosphate nanoparticles with repeated ion-recharge and re-releases

al-Qarni, F. D., Tay, F. C. M., Weir, M. D., Melo, M. A. S., Sun, J., Oates, T. W., Xie, X. & Xu, H. H. K., Nov 2018, In : Journal of Dentistry. 78, p. 91-99 9 p.

Research output: Contribution to journal › Article

Phosphorylcholine
Adhesives
Nanoparticles
Ions
Biofilms
4 Citations (Scopus)

Quaternary ammonium silane-based antibacterial and anti-proteolytic cavity cleanser

Gou, Y. P., Li, J. Y., Meghil, M. M., Cutler, C. W., Xu, H. H. K., Tay, F. R. & Niu, L. N., Dec 2018, In : Dental Materials. 34, 12, p. 1814-1827 14 p.

Research output: Contribution to journal › Article

Silanes
Ammonium Compounds
Dentin
Control Groups
Permeability
3 Citations (Scopus)

Release of ICTP and CTX telopeptides from demineralized dentin matrices: Effect of time, mass and surface area

Turco, G., Cadenaro, M., Maravić, T., Frassetto, A., Marsich, E., Mazzoni, A., Di Lenarda, R., Tay, F. R., Pashley, D. H. & Breschi, L., Mar 2018, In : Dental Materials. 34, 3, p. 452-459 8 p.

Research output: Contribution to journal › Article

Matrix Metalloproteinases
Collagen
Aging of materials
Artificial Saliva
Dentin
7 Citations (Scopus)

Synergistic mechanism of Ag+-Zn2+ in anti-bacterial activity against Enterococcus faecalis and its application against dentin infection

Fan, W., Sun, Q., Li, Y., Tay, F. R. & Fan, B., Jan 31 2018, In : Journal of Nanobiotechnology. 16, 1, 10.

Research output: Contribution to journal › Article

Enterococcus faecalis
Biofilms
Dentin
Cytotoxicity
Chlorhexidine