Franklin Chi Meng Tay

Department Chair

  • 34930 Citations
  • 97 h-Index
1984 …2020
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Research Output 1984 2020

2011
26 Citations (Scopus)

Inhibition of MMPs by alcohols

Tezvergil-Mutluay, A., Agee, K. A., Hoshika, T., Uchiyama, T., Tjäderhane, L., Breschi, L., Mazzoni, A., Thompson, J. M., McCracken, C. E., Looney, S. W., Tay, F. C. M. & Pashley, D. H., Sep 1 2011, In : Dental Materials. 27, 9, p. 926-933 8 p.

Research output: Contribution to journalArticle

Matrix Metalloproteinases
Alcohols
Ethanol
Dentin
Heptanol
23 Citations (Scopus)

Inorganic-organic nanocomposite assembly using collagen as a template and sodium tripolyphosphate as a biomimetic analog of matrix phosphoprotein

Dai, L., Qi, Y. P., Niu, L. N., Liu, Y., Pucci, C. R., Looney, S. W., Ling, J. Q., Pashley, D. H. & Tay, F. C. M., Aug 3 2011, In : Crystal Growth and Design. 11, 8, p. 3504-3511 8 p.

Research output: Contribution to journalArticle

Phosphoproteins
biomimetics
Biomimetics
Apatites
collagens
95 Citations (Scopus)

Intrafibrillar collagen mineralization produced by biomimetic hierarchical nanoapatite assembly

Liu, Y., Li, N., Qi, Y. P., Dai, L., Bryan, T. E., Mao, J., Pashley, D. H. & Tay, F. C. M., Feb 22 2011, In : Advanced Materials. 23, 8, p. 975-980 6 p.

Research output: Contribution to journalArticle

Biomimetics
Collagen
Apatites
Extracellular Matrix Proteins
Apatite
14 Citations (Scopus)

In vivo effects of fluoride on enamel permeability

Chersoni, S., Bertacci, A., Pashley, D. H., Tay, F. C. M., Montebugnoli, L. & Prati, C., Aug 1 2011, In : Clinical oral investigations. 15, 4, p. 443-449 7 p.

Research output: Contribution to journalArticle

Dental Enamel
Fluorides
Permeability
Tooth
Acidulated Phosphate Fluoride
326 Citations (Scopus)

Limitations in bonding to dentin and experimental strategies to prevent bond degradation

Liu, Y., Tjäderhane, L., Breschi, L., Mazzoni, A., Li, N., Mao, J., Pashley, D. H. & Tay, F. C. M., Aug 1 2011, In : Journal of Dental Research. 90, 8, p. 953-968 16 p.

Research output: Contribution to journalReview article

Dentin
Matrix Metalloproteinases
Cathepsins
Collagen
Water
49 Citations (Scopus)

Localization of MMP-2, MMP-9, TIMP-1, and TIMP-2 in human coronal dentine

Niu, L. N., Zhang, L., Jiao, K., Li, F., Ding, Y. X., Wang, D. Y., Wang, M. Q., Tay, F. C. M. & Chen, J. H., Aug 1 2011, In : Journal of Dentistry. 39, 8, p. 536-542 7 p.

Research output: Contribution to journalArticle

Tissue Inhibitor of Metalloproteinase-2
Tissue Inhibitor of Metalloproteinase-1
Matrix Metalloproteinase 2
Matrix Metalloproteinase 9
Dentin
10 Citations (Scopus)

Matrix metalloproteinase-2 expression induced by two different adhesive systems on human pulp fibroblasts

Orsini, G., Mazzoni, A., Orciani, M., Putignano, A., Procaccini, M., Falconi, M., Pashley, D. H., Tay, F. R. & Breschi, L., Dec 1 2011, In : Journal of Endodontics. 37, 12, p. 1663-1667 5 p.

Research output: Contribution to journalArticle

Matrix Metalloproteinase 2
Adhesives
Fibroblasts
Culture Media
Dentin
35 Citations (Scopus)

MMP-2 assay within the hybrid layer created by a two-step etch-and-rinse adhesive: Biochemical and immunohistochemical analysis

Mazzoni, A., Carrilho, M., Papa, V., Tjäderhane, L., Gobbi, P., Nucci, C., Di Lenarda, R., Mazzotti, G., Tay, F. C. M., Pashley, D. H. & Breschi, L., Jul 1 2011, In : Journal of Dentistry. 39, 7, p. 470-477 8 p.

Research output: Contribution to journalArticle

Matrix Metalloproteinase 2
Adhesives
Dentin
Chlorhexidine
Powders
3 Citations (Scopus)

New method of measuring water permeability of adhesive resin films

Sword, R. J., Sword, J. J., Brackett, W. W., Tay, F. R., Pashley, D. H. & García-Godoy, F., Feb 1 2011, In : American journal of dentistry. 24, 1, p. 20-26 7 p.

Research output: Contribution to journalArticle

Adhesives
Permeability
Water
Steam
Stainless Steel

Reply to Drs Pai and Thomas

Tay, F. C. M., Jun 1 2011, In : Journal of Endodontics. 37, 6, p. 741-743 3 p.

Research output: Contribution to journalLetter

18 Citations (Scopus)

Resin-dentin bonds to EDTA-treated vs. acid-etched dentin using ethanol wet-bonding. Part II: Effects of mechanical cycling load on microtensile bond strengths

Sauro, S., Toledano, M., Aguilera, F. S., Mannocci, F., Pashley, D. H., Tay, F. C. M., Watson, T. F. & Osorio, R., Jun 1 2011, In : Dental Materials. 27, 6, p. 563-572 10 p.

Research output: Contribution to journalArticle

Ethylenediaminetetraacetic acid
Dentin
Edetic Acid
Ethanol
Resins
108 Citations (Scopus)

Setting properties and cytotoxicity evaluation of a premixed bioceramic root canal sealer

Loushine, B. A., Bryan, T. E., Looney, S. W., Gillen, B. M., Loushine, R. J., Weller, R. N., Pashley, D. H. & Tay, F. C. M., May 1 2011, In : Journal of Endodontics. 37, 5, p. 673-677 5 p.

Research output: Contribution to journalArticle

Dental Pulp Cavity
Confidence Intervals
Epoxy Resins
Silicates
Succinate Dehydrogenase
456 Citations (Scopus)

State of the art etch-and-rinse adhesives

Pashley, D. H., Tay, F. C. M., Breschi, L., Tjäderhane, L., Carvalho, R. M., Carrilho, M. & Tezvergil-Mutluay, A., Jan 1 2011, In : Dental Materials. 27, 1, p. 1-16 16 p.

Research output: Contribution to journalArticle

Dentin
Adhesives
Resins
Durability
Protease Inhibitors
23 Citations (Scopus)

Subtleties of biomineralisation revealed by manipulation of the eggshell membrane

Li, N., Niu, L. N., Qi, Y. P., Yiu, C. K. Y., Ryou, H., Arola, D. D., Chen, J. H., Pashley, D. H. & Tay, F. C. M., Dec 1 2011, In : Biomaterials. 32, 34, p. 8743-8752 10 p.

Research output: Contribution to journalArticle

Egg Shell
Biomineralization
Membranes
Minerals
Biomimetics
61 Citations (Scopus)

The anti-MMP activity of benzalkonium chloride

Tezvergil-Mutluay, A., Mutluay, M. M., Gu, L. S., Zhang, K., Agee, K. A., Carvalho, R. M., Manso, A., Carrilho, M., Tay, F. R., Breschi, L., Suh, B. I. & Pashley, D. H., Jan 1 2011, In : Journal of Dentistry. 39, 1, p. 57-64 8 p.

Research output: Contribution to journalArticle

Benzalkonium Compounds
Matrix Metalloproteinases
Dentin
Powders
Collagen
55 Citations (Scopus)

The critical barrier to progress in dentine bonding with the etch-and-rinse technique

Brackett, M. G., Li, N., Brackett, W. W., Sword, R. J., Qi, Y. P., Niu, L. N., Pucci, C. R., Dib, A., Pashley, D. H. & Tay, F. R., Mar 1 2011, In : Journal of Dentistry. 39, 3, p. 238-248 11 p.

Research output: Contribution to journalArticle

Biomimetics
Dentin
Adhesives
Chlorhexidine
Water
86 Citations (Scopus)

The effect of QMix, an experimental antibacterial root canal irrigant, on removal of canal wall smear layer and debris

Dai, L., Khechen, K., Khan, S., Gillen, B., Loushine, B. A., Wimmer, C. E., Gutmann, J. L., Pashley, D. & Tay, F. R., Jan 1 2011, In : Journal of Endodontics. 37, 1, p. 80-84 5 p.

Research output: Contribution to journalArticle

Root Canal Irrigants
Smear Layer
Edetic Acid
Dental Specialties
Dental Pulp Cavity
95 Citations (Scopus)

The inhibitory effects of quaternary ammonium methacrylates on soluble and matrix-bound MMPs

Tezvergil-Mutluay, A., Agee, K. A., Uchiyama, T., Imazato, S., Mutluay, M. M., Cadenaro, M., Breschi, L., Nishitani, Y., Tay, F. R. & Pashley, D. H., Apr 1 2011, In : Journal of Dental Research. 90, 4, p. 535-540 6 p.

Research output: Contribution to journalArticle

Methacrylates
Matrix Metalloproteinases
Ammonium Compounds
Dentin
Chlorhexidine
55 Citations (Scopus)

The use of sodium trimetaphosphate as a biomimetic analog of matrix phosphoproteins for remineralization of artificial caries-like dentin

Liu, Y., Li, N., Qi, Y., Niu, L. N., Elshafiy, S., Mao, J., Breschi, L., Pashley, D. H. & Tay, F. C. M., May 1 2011, In : Dental Materials. 27, 5, p. 465-477 13 p.

Research output: Contribution to journalArticle

Biomimetics
carbopol 940
Phosphoproteins
Dentin
Adhesives
77 Citations (Scopus)

Zinc reduces collagen degradation in demineralized human dentin explants

Osorio, R., Yamauti, M., Osorio, E., Ruiz-Requena, M. E., Pashley, D. H., Tay, F. C. M. & Toledano, M., Feb 1 2011, In : Journal of Dentistry. 39, 2, p. 148-153 6 p.

Research output: Contribution to journalArticle

Dentin
Zinc
Collagen
Doxycycline
Metalloproteases
2010
43 Citations (Scopus)

A chemical phosphorylation-inspired design for Type i collagen biomimetic remineralization

Gu, L. S., Kim, J., Kim, Y. K., Liu, Y., Dickens, S. H., Pashley, D. H., Ling, J. Q. & Tay, F. R., Nov 1 2010, In : Dental Materials. 26, 11, p. 1077-1089 13 p.

Research output: Contribution to journalArticle

Biomimetics
Phosphorylation
Dentin
Collagen
carbopol 940
18 Citations (Scopus)

An all-in-one adhesive does not etch beyond hybrid layers

Kim, J., Mai, S., Carrilho, M. R., Yiu, C. K. Y., Pashley, D. H. & Tay, F. R., May 1 2010, In : Journal of Dental Research. 89, 5, p. 482-487 6 p.

Research output: Contribution to journalArticle

Dentin
Adhesives
Biomimetics
Glycine
Buffers
21 Citations (Scopus)

Antimicrobial efficacy of 3.8% silver diamine fluoride and its effect on root dentin

Hiraishi, N., Yiu, C. K. Y., King, N. M., Tagami, J. & Tay, F. C. M., Apr 23 2010, In : Journal of Endodontics. 36, 6, p. 1026-1029 4 p.

Research output: Contribution to journalArticle

Dentin
Silver
Enterococcus faecalis
Bandages
Biofilms
49 Citations (Scopus)

Biomimetic remineralization as a progressive dehydration mechanism of collagen matrices - Implications in the aging of resin-dentin bonds

Kim, Y. K., Mai, S., Mazzoni, A., Liu, Y., Tezvergil-Mutluay, A., Takahashi, K., Zhang, K., Pashley, D. H. & Tay, F. R., Jan 1 2010, In : Acta biomaterialia. 6, 9, p. 3729-3739 11 p.

Research output: Contribution to journalArticle

Biomimetics
Adhesive joints
Dentin
Dehydration
Collagen
83 Citations (Scopus)

Canal and isthmus debridement efficacies of two irrigant agitation techniques in a closed system

Susin, L., Liu, Y., Yoon, J. C., Parente, J. M., Loushine, R. J., Ricucci, D., Bryan, T., Weller, R. N., Pashley, D. H. & Tay, F. R., Dec 1 2010, In : International Endodontic Journal. 43, 12, p. 1077-1090 14 p.

Research output: Contribution to journalArticle

Debridement
Pressure
Tooth
Endodontics
Adhesives
5 Citations (Scopus)

Can caries-affected dentin be completely remineralized by guided tissue remineralization?

Dai, L., Liu, Y., Salameh, Z., Khan, S., Mao, J., Pashley, D. H. & Tay, F. C. M., Oct 1 2010, In : Dental Hypotheses. 1, 2, p. 59-68 10 p.

Research output: Contribution to journalArticle

Dentin
Apatites
Biomimetics
Seeds
Collagen
24 Citations (Scopus)

Changes in stiffness of resin-infiltrated demineralized dentin after remineralization by a bottom-up biomimetic approach

Gu, L. S., Huffman, B. P., Arola, D. D., Kim, Y. K., Mai, S., Elsalanty, M. E., Ling, J. Q., Pashley, D. H. & Tay, F. C. M., Apr 1 2010, In : Acta biomaterialia. 6, 4, p. 1453-1461 9 p.

Research output: Contribution to journalArticle

Biomimetics
Dentin
Resins
Stiffness
Minerals
86 Citations (Scopus)

Chlorhexidine binding to mineralized versus demineralized dentin powder

Kim, J., Uchiyama, T., Carrilho, M., Agee, K. A., Mazzoni, A., Breschi, L., Carvalho, R. M., Tjäderhane, L., Looney, S. W., Wimmer, C., Tezvergil-Mutluay, A., Tay, F. C. M. & Pashley, D. H., Aug 1 2010, In : Dental Materials. 26, 8, p. 771-778 8 p.

Research output: Contribution to journalArticle

Chlorhexidine
Dentin
Powders
Ultraviolet spectroscopy
Ethanol
17 Citations (Scopus)
Resin Cements
Chlorhexidine
Polymethyl Methacrylate
Polymethyl methacrylates
Cements
206 Citations (Scopus)

Chlorhexidine stabilizes the adhesive interface: A 2-year in vitro study

Breschi, L., Mazzoni, A., Nato, F., Carrilho, M., Visintini, E., Tjäderhane, L., Ruggeri, A., Tay, F. C. M., Dorigo, E. D. S. & Pashley, D. H., Apr 1 2010, In : Dental Materials. 26, 4, p. 320-325 6 p.

Research output: Contribution to journalArticle

Chlorhexidine
Dentin
varespladib methyl
Adhesives
Matrix Metalloproteinases
94 Citations (Scopus)

Critical Review on Methacrylate Resin-based Root Canal Sealers

Kim, Y. K., Grandini, S., Ames, J. M., Gu, L. S., Kim, S. K., Pashley, D. H., Gutmann, J. L. & Tay, F. C. M., Mar 1 2010, In : Journal of Endodontics. 36, 3, p. 383-399 17 p.

Research output: Contribution to journalReview article

Methacrylates
Dental Pulp Cavity
Adhesives
Root Canal Filling Materials
Dentin
148 Citations (Scopus)

Cysteine Cathepsins in Human Dentin-Pulp Complex

Tersariol, I. L., Geraldeli, S., Minciotti, C. L., Nascimento, F. D., Pääkkönen, V., Martins, M. T., Carrilho, M. R., Pashley, D. H., Tay, F. C. M., Salo, T. & Tjäderhane, L., Mar 1 2010, In : Journal of Endodontics. 36, 3, p. 475-481 7 p.

Research output: Contribution to journalArticle

Cathepsins
Dentin
Odontoblasts
Cysteine
Matrix Metalloproteinases
28 Citations (Scopus)

Differential aggressiveness of ethylenediamine tetraacetic acid in causing canal wall erosion in the presence of sodium hypochlorite

Mai, S., Kim, Y. K., Arola, D. D., Gu, L. S., Kim, J. R., Pashley, D. H. & Tay, F. R., Mar 1 2010, In : Journal of Dentistry. 38, 3, p. 201-206 6 p.

Research output: Contribution to journalArticle

ethylenediamine
Sodium Hypochlorite
Dentin
Acids
Tooth Root
47 Citations (Scopus)

Differential expression of matrix metalloproteinase-2 in human coronal and radicular sound and carious dentine

Toledano, M., Nieto-Aguilar, R., Osorio, R., Campos, A., Osorio, E., Tay, F. C. M. & Alaminos, M., Aug 1 2010, In : Journal of Dentistry. 38, 8, p. 635-640 6 p.

Research output: Contribution to journalArticle

Dental Caries
Dentin
Matrix Metalloproteinase 2
Fluorescent Antibody Technique
Fluorescein-5-isothiocyanate
59 Citations (Scopus)

Effect of chlorhexidine incorporation into a self-etching primer on dentine bond strength of a luting cement

Hiraishi, N., Yiu, C. K. Y., King, N. M. & Tay, F. R., Jun 2010, In : Journal of Dentistry. 38, 6, p. 496-502 7 p.

Research output: Contribution to journalArticle

Chlorhexidine
Dentin
Enterococcus faecalis
Electron Scanning Microscopy
Resin Cements
7 Citations (Scopus)

Effect of surface preparation on bond strength of resin luting cements to dentin

Peerzada, F., Yiu, C. K. Y., Hiraishi, N., Tay, F. C. M. & King, N. M., Nov 1 2010, In : Operative dentistry. 35, 6, p. 624-633 10 p.

Research output: Contribution to journalArticle

Resin Cements
Dentin
AIDS-Related Complex
Diamond
United Nations
173 Citations (Scopus)

Effect of Vapor Lock on Root Canal Debridement by Using a Side-vented Needle for Positive-pressure Irrigant Delivery

Tay, F. R., Gu, L. S., Schoeffel, G. J., Wimmer, C., Ferreira Susin, L., Zhang, K., Arun, S. N., Kim, J., Looney, S. W. & Pashley, D. H., Jan 1 2010, In : Journal of Endodontics. 36, 4, p. 745-750 6 p.

Research output: Contribution to journalArticle

Tooth Apex
Dental Pulp Cavity
Debridement
Needles
Pressure
86 Citations (Scopus)

Effects of Different Exposure Times and Concentrations of Sodium Hypochlorite/Ethylenediaminetetraacetic Acid on the Structural Integrity of Mineralized Dentin

Zhang, K., Kim, Y. K., Cadenaro, M., Bryan, T. E., Sidow, S. J., Loushine, R. J., Ling, J. Q., Pashley, D. H. & Tay, F. C. M., Jan 1 2010, In : Journal of Endodontics. 36, 1, p. 105-109 5 p.

Research output: Contribution to journalArticle

Sodium Hypochlorite
Dentin
Edetic Acid
Collagen
Powders
89 Citations (Scopus)

Ethanol wet-bonding challenges current anti-degradation strategy

Sadek, F. T., Braga, R. R., Muench, A., Liu, Y., Pashley, D. H. & Tay, F. C. M., Dec 1 2010, In : Journal of Dental Research. 89, 12, p. 1499-1504 6 p.

Research output: Contribution to journalArticle

Dentin
Chlorhexidine
Ethanol
Water
Adhesives
37 Citations (Scopus)

Ethanol wet-bonding technique sensitivity assessed by AFM

Osorio, E., Toledano, M., Aguilera, F. S., Tay, F. C. M. & Osorio, R., Nov 1 2010, In : Journal of Dental Research. 89, 11, p. 1264-1269 6 p.

Research output: Contribution to journalArticle

Ethanol
Dentin
Dehydration
Water
Collagen
30 Citations (Scopus)

Failure of a glass ionomer to remineralize apatite-depleted dentin

Kim, Y. K., Yiu, C. K. Y., Kim, J. R., Gu, L., Kim, S. K., Weller, R. N., Pashley, D. H. & Tay, F. C. M., Mar 1 2010, In : Journal of Dental Research. 89, 3, p. 230-235 6 p.

Research output: Contribution to journalArticle

Apatites
Dentin
Glass Ionomer Cements
Strontium
carbopol 940
59 Citations (Scopus)

Final Rinse Optimization: Influence of Different Agitation Protocols

Paragliola, R., Franco, V., Fabiani, C., Mazzoni, A., Nato, F., Tay, F. R., Breschi, L. & Grandini, S., Feb 1 2010, In : Journal of Endodontics. 36, 2, p. 282-285 4 p.

Research output: Contribution to journalArticle

Gutta-Percha
Plastics
Endodontics
Ultrasonics
Root Canal Irrigants
61 Citations (Scopus)

Functional biomimetic analogs help remineralize apatite-depleted demineralized resin-infiltrated dentin via a bottom-up approach

Kim, J., Arola, D. D., Gu, L., Kim, Y. K., Mai, S., Liu, Y., Pashley, D. H. & Tay, F. C. M., Jul 2010, In : Acta biomaterialia. 6, 7, p. 2740-2750 11 p.

Research output: Contribution to journalArticle

Apatites
Biomimetics
Apatite
Dentin
Collagen
4 Citations (Scopus)

Hardness, elasticity and ultrastructure of primary tooth dentin bonded with a self-reinforcing one-step self-etch adhesive

Hosoya, Y., Tay, F. R., Ono, T. & Miyazaki, M., Mar 1 2010, In : Journal of Dentistry. 38, 3, p. 214-221 8 p.

Research output: Contribution to journalArticle

Deciduous Tooth
Elasticity
Hardness
Dentin
Adhesives
18 Citations (Scopus)

Imperfect hybrid layers created by an aggressive one-step self-etch adhesive in primary dentin are amendable to biomimetic remineralization in vitro

Kim, J., Vaughn, R. M., Gu, L., Rockman, R. A., Arola, D. D., Schafer, T. E., Choi, K. K., Pashley, D. H. & Tay, F. R., Jun 15 2010, In : Journal of Biomedical Materials Research - Part A. 93, 4, p. 1225-1234 10 p.

Research output: Contribution to journalArticle

Biomimetics
Dentin
Adhesives
rhodamine B
Resins
29 Citations (Scopus)

Implication of ethanol wet-bonding in hybrid layer remineralization

Kim, J., Gu, L., Breschi, L., Tjäderhane, L., Choi, K. K., Pashley, D. H. & Tay, F. R., Jun 1 2010, In : Journal of Dental Research. 89, 6, p. 575-580 6 p.

Research output: Contribution to journalArticle

Ethanol
Biomimetics
Water
Apatites
Dentin
9 Citations (Scopus)

Influence of application parameters on bond strength of "an all in one" water-based self-etching primer/adhesive after 6 and 12 months of water aging

Osorio, R., Osorio, E., Aguilera, F. S., Tay, F. R., Pinto, A. & Toledano, M., Jul 28 2010, In : Odontology. 98, 2, p. 117-125 9 p.

Research output: Contribution to journalArticle

Adhesives
Water
Dentin
Transmission Electron Microscopy
Electron Scanning Microscopy
44 Citations (Scopus)

Influence of different initiators on the degree of conversion of experimental adhesive blends in relation to their hydrophilicity and solvent content

Cadenaro, M., Antoniolli, F., Codan, B., Agee, K., Tay, F. R., Dorigo, E. D. S., Pashley, D. H. & Breschi, L., Apr 1 2010, In : Dental Materials. 26, 4, p. 288-294 7 p.

Research output: Contribution to journalArticle

phosphine
Hydrophilicity
Hydrophobic and Hydrophilic Interactions
Adhesives
Oxides
112 Citations (Scopus)

Internal root resorption: A review

Patel, S., Ricucci, D., Durak, C. & Tay, F., May 19 2010, In : Journal of Endodontics. 36, 7, p. 1107-1121 15 p.

Research output: Contribution to journalReview article

Root Resorption
Dental Pulp Cavity
Cone-Beam Computed Tomography
Differential Diagnosis
Diathermy
32 Citations (Scopus)

In vitro osteogenic potential of an experimental calcium silicate-based root canal sealer

Bryan, T. E., Khechen, K., Brackett, M. G., Messer, R. L. W., El-Awady, A., Primus, C. M., Gutmann, J. L. & Tay, F. R., May 6 2010, In : Journal of Endodontics. 36, 7, p. 1163-1169 7 p.

Research output: Contribution to journalArticle

Dental Pulp Cavity
Alkaline Phosphatase
Immersion
Extracellular Matrix
Zinc Oxide