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Article
1985

Patterns of genetic diversity among class II histocompatibility genes in wild mice

McConnell, T. J., McIndoe, R. A. & Wakeland, E. K., Jan 1 1985, In : Federation Proceedings. 44, 3

Research output: Contribution to journalArticle

1986
3 Scopus citations
1988

The origin of MHC class II gene polymorphism within the genus Mus

McConnell, T. J., Talbot, W. S., McIndoe, R. A. & Wakeland, E. K., Jan 1 1988, In : Nature. 332, 6165, p. 651-654 4 p.

Research output: Contribution to journalArticle

85 Scopus citations
1990

Ancestral polymorphisms of MHC class II genes: Divergent allele advantage

Wakeland, E. K., Boehme, S., She, J. X., Lu, C. C., McIndoe, R. A., Cheng, I., Ye, Y. & Potts, W. K., Jun 1 1990, In : Immunologic Research. 9, 2, p. 115-122 8 p.

Research output: Contribution to journalArticle

77 Scopus citations
1995

Single-tube genomic DNA isolation from whole blood without pre-isolating white blood cells

McIndoe, R. A., Linhardt, M. S. & Hood, L., Jan 1 1995, In : BioTechniques. 19, 1, p. 30+32-33

Research output: Contribution to journalArticle

8 Scopus citations
1996

An analysis of the dynamic range and linearity of an infrared DNA sequencer

McIndoe, R. A., Hood, L. & Bumgarner, R. E., Apr 1 1996, In : ELECTROPHORESIS. 17, 4, p. 652-658 7 p.

Research output: Contribution to journalArticle

11 Scopus citations

Detection of a large RIII-derived chromosomal segment on chromosome 10 in the H-2 congenic strain B10.RIII(71NS)/Sn

Dong, P., Hood, L. & McIndoe, R. A., Jan 15 1996, In : Genomics. 31, 2, p. 266-269 4 p.

Research output: Contribution to journalArticle

7 Scopus citations
1997

Data-adaptive algorithms for calling alleles in repeat polymorphisms

Stoughton, R., Bumgarner, R., Frederick, W. J. & McIndoe, R. A., Jan 1 1997, In : ELECTROPHORESIS. 18, 1, p. 1-5 5 p.

Research output: Contribution to journalArticle

4 Scopus citations

Linkage analysis of 49 high-risk families does not support a common familial prostate cancer-susceptibility gene at 1q24-25

McIndoe, R. A., Stanford, J. L., Gibbs, M., Jarvik, G. P., Brandzel, S., Neal, C. L., Li, S., Gammack, J. T., Gay, A. A., Goode, E. L., Hood, L. & Ostrander, E. A., Aug 1997, In : American journal of human genetics. 61, 2, p. 347-353 7 p.

Research output: Contribution to journalArticle

104 Scopus citations
1999

Evidence for a rare prostate cancer-susceptibility locus at chromosome 1p36

Gibbs, M., Stanford, J. L., McIndoe, R. A., Jarvik, G. P., Kolb, S., Goode, E. L., Chakrabarti, L., Schuster, E. F., Buckley, V. A., Miller, E. L., Brandzel, S., Li, S., Hood, L. & Ostrander, E. A., 1999, In : American journal of human genetics. 64, 3, p. 776-787 12 p.

Research output: Contribution to journalArticle

274 Scopus citations

Localization of non-Mhc collagen-induced arthritis susceptibility loci in DBA/1j mice

Mcindoe, R. A., Bohlman, B., Chi, E., Schuster, E., Lindhardt, M. & Hood, L., Mar 2 1999, In : Proceedings of the National Academy of Sciences of the United States of America. 96, 5, p. 2210-2214 5 p.

Research output: Contribution to journalArticle

68 Scopus citations
2000

Linkage analysis of 150 high-risk prostate cancer families at 1q24-25

Goode, E. L., Stanford, J. L., Chakrabarti, L., Gibbs, M., Kolb, S., McIndoe, R. A., Buckley, V. A., Schuster, E. F., Neal, C. L., Miller, E. L., Brandzel, S., Hood, L., Ostrander, E. A. & Jarvik, G. P., Mar 2000, In : Genetic Epidemiology. 18, 3, p. 251-275 25 p.

Research output: Contribution to journalArticle

41 Scopus citations

WECHE: A novel hematopoietic regulatory factor

Ohneda, O., Ohneda, K., Nomiyama, H., Zheng, Z., Gold, S. A., Arai, F., Miyamoto, T., Taillon, B. E., McIndoe, R. A., Shimkets, R. A., Lewin, D. A., Suda, T. & Lasky, L. A., Feb 1 2000, In : Immunity. 12, 2, p. 141-150 10 p.

Research output: Contribution to journalArticle

Open Access
29 Scopus citations
2001

A statistical method for flagging weak spots improves normalization and ratio estimates in microarrays.

Yang, M. C., Ruan, Q. G., Yang, J. J., Eckenrode, S., Wu, S., McIndoe, R. A. & She, J. X., Oct 10 2001, In : Physiological Genomics. 7, 1, p. 45-53 9 p.

Research output: Contribution to journalArticle

95 Scopus citations

Rapid decrease of RNA level of a novel mouse mitochondria solute carrier protein (Mscp) gene at 4-5 weeks of age

Li, Q. Z., Eckenrode, S., Ruan, Q. G., Wang, C. Y., Shi, J. D., McIndoe, R. A. & She, J-X., Jan 1 2001, In : Mammalian Genome. 12, 11, p. 830-836 7 p.

Research output: Contribution to journalArticle

4 Scopus citations
2003

Gene expression associated with interferon alfa antiviral activity in an HCV replicon cell line

Zhu, H., Zhao, H., Collins, C. D., Eckenrode, S. E., Run, Q., McIndoe, R. A., Crawford, J. M., Nelson, D. R., She, J. X. & Liu, C., May 1 2003, In : Hepatology. 37, 5, p. 1180-1188 9 p.

Research output: Contribution to journalArticle

95 Scopus citations

Gene expression profiling during all-trans retinoic acid-induced cell differentiation of acute promyelocytic leukemia cells

Yang, L., Zhao, H., Li, S. W., Ahrens, K., Collins, C., Eckenrode, S., Ruan, Q. G., McIndoe, R. A. & She, J-X., Nov 2003, In : Journal of Molecular Diagnostics. 5, 4, p. 212-221 10 p.

Research output: Contribution to journalArticle

26 Scopus citations

MADGE: Scalable distributed data management software for cDNA microarrays

McIndoe, R. A., Lanzen, A. & Hurtz, K., Jan 1 2003, In : Bioinformatics. 19, 1, p. 87-89 3 p.

Research output: Contribution to journalArticle

2 Scopus citations

Microarray analysis of gene expression in the kidneys of new- and post-onset diabetic NOD mice

Wilson, K. H. S., Eckenrode, S. E., Li, Q. Z., Ruan, Q. G., Yang, P., Shi, J. D., Davoodi-Semiromi, A., McIndoe, R. A., Croker, B. P. & She, J-X., Aug 1 2003, In : Diabetes. 52, 8, p. 2151-2159 9 p.

Research output: Contribution to journalArticle

52 Scopus citations
2004

Gene Expression Profiles Define a Key Checkpoint for Type 1 Diabetes in NOD Mice

Eckenrode, S. E., Ruan, Q., Yang, P., Zheng, W., McIndoe, R. A. & She, J-X., Feb 1 2004, In : Diabetes. 53, 2, p. 366-375 10 p.

Research output: Contribution to journalArticle

27 Scopus citations

Microarray experimental design: Power and sample size considerations

Yang, M. C. K., Yang, J. J., McIndoe, R. A. & She, J. X., Apr 1 2004, In : Physiological Genomics. 16, p. 24-28 5 p.

Research output: Contribution to journalArticle

40 Scopus citations

Molecular pathways altered by insulin B9-23 immunization

Eckenrode, S. E., Ruan, Q. G., Collins, C. D., Yang, P., McIndoe, R. A., Muir, A. & She, J-X., Jan 1 2004, In : Annals of the New York Academy of Sciences. 1037, p. 175-185 11 p.

Research output: Contribution to journalArticle

4 Scopus citations
2005

Alterations of renal phenotype and gene expression profiles due to protein overload in NOD-related mouse strains

Wilson, K. H. S., McIndoe, R. A., Eckenrode, S., Morel, L., Agarwal, A., Croker, B. P. & She, J. X., Dec 21 2005, In : BMC Nephrology. 6, 17.

Research output: Contribution to journalArticle

6 Scopus citations
5 Scopus citations
2006

Early pathogenic events associated with Sjögren's syndrome (SjS)-like disease of the nod mouse using microarray analysis

Killedar, S. Y., Eckenrode, S. E., McIndoe, R. A., She, J. X., Nguyen, C. Q., Peck, A. B. & Cha, S. R., Dec 2 2006, In : Laboratory Investigation. 86, 12, p. 1243-1260 18 p.

Research output: Contribution to journalArticle

45 Scopus citations

Intergeneration CAG expansion and contraction in a Chinese HD family

Tang, Y., Wang, Y., Yang, P., Liu, Y., Wang, B., Podolsky, R., McIndoe, R. A. & Wang, C. Y., Apr 5 2006, In : American Journal of Medical Genetics - Neuropsychiatric Genetics. 141 B, 3, p. 242-244 3 p.

Research output: Contribution to journalArticle

11 Scopus citations

The application of genomic and proteomic technologies in predictive, preventive and personalized medicine

Collins, C. D., Purohit, S., Podolsky, R. H., Zhao, H. S., Schatz, D., Eckenrode, S. E., Yang, P., Hopkins, D., Muir, A., Hoffman, M., McIndoe, R. A., Rewers, M. & She, J. X., Nov 1 2006, In : Vascular Pharmacology. 45, 5, p. 258-267 10 p.

Research output: Contribution to journalArticle

47 Scopus citations
2007

A high-throughput population screening system for the estimation of genetic risk for type 1 diabetes: An application for the TEDDY (The Environmental Determinants of Diabetes in the Young) study

Kiviniemi, M., Hermann, R., Nurmi, J., Ziegler, A. G., Knip, M., Simell, O., Veijola, R., Lövgren, T., Ilonen, J., Rewers, M., Barriga, K., Baxter, J., Deas, A., Eisenbarth, G., Emery, L., Gesualdo, P., Hoffman, M., Norris, J., Waugh, K., Weber, S. & 88 others, She, J-X., Muir, A., Schatz, D., Hopkins, D., Steed, L., Choate, A., Silvis, K., Shankar, M., Huang, Y. H., Yang, P., Zheng, W. P., Wang, H. J., English, K., McIndoe, R. A., Bonifacio, E., Baumgarten, A., Hummel, S., Kersting, M., Koenig, S., Knopff, A., Locher, A., Roth, R., Schoen, S., Schwaiger, P., Sichert-Hellert, W., Winkler, C., Zimmermann, D., Nanto-Salonen, K., Simell, T., Uusitalo, U., Hyöty, H., Virtanen, S. M., Kronberg-Kippilä, C., Torma, M., Ruohonen, E., Romo, M., Mantymaki, E., Niininen, T., Nyblom, M., Stenius, A., Lernmark, Å., Almgren, P., Andrén-Aronsson, C., Andersson, E., Bianconi-Svensson, S., Carlsson, U. M., Cilio, C., Gerardsson, J., Gustavsson, B., Hansson, A., Hansson, G., Hansson, I., Ivarsson, S., Larsson, H., Karlsson, E., Katsarou, A., Lernmark, B., Massadakis, T., Nilsson, A., Järvirova, M. S., Sjöberg, B., Wallin, A., Wimar, Å., Hagopian, W. A., Brantley, M., Cowen, C., Hui, P., Hay, K. M., Jackson, M., Stepikova, V., Ugale, J., Krischer, J. P., Bray, C., Cuthbertson, D., Gowda, V., Hunt, K., Liu, S., Malloy, J., McCarthy, C., McLeod, W., Moyers, S., Nallamshetty, L., Smith, S., Akolkar, B., Briese, T., Erlich, H., Johnson, S. B. & Oberste, S., Oct 1 2007, In : Diabetes Technology and Therapeutics. 9, 5, p. 460-472 13 p.

Research output: Contribution to journalArticle

44 Scopus citations

The Environmental Determinants of Diabetes in the Young (TEDDY) study: Study design

Krischer, J., Rewers, M., Barriga, K., Baxter, J., Deas, A., Eisenbarth, G., Emery, L., Gesualdo, P., Hoffman, M., Norris, J., Waugh, K., Weber, S., She, J-X., Muir, A., Schatz, D., Hopkins, D., Steed, L., Silvis, K., Shankar, M., huang, Y. H. & 84 others, Yang, P., Zheng, W. P., Wang, H. J., English, K., McIndoe, R. A., Ziegler, A. G., Bonifacio, E., Baumgarten, A., Hummel, S., Kersting, M., Koenig, S., Knopff, A., Locher, A., Roth, R., Schoen, S., Schwaiger, P., Sichert-Hellert, W., Winkler, C., Zimmermann, D., Simell, O. G., Nanto-Salonen, K., Ilonen, J., Knip, M., Veijola, R., Simell, T., Uusitalo, U., Hyöty, H., Virtanen, S. M., Kronberg-Kippila̧, C., Torma, M., Ruohonen, E., Romo, M., Mantymaki, E., Niininen, T., Nyblom, M., Stenius, A., Lernmark, Å., Almgren, P., Andrén-Aronsson, C., Andersson, E., Bianconi-Svensson, S., Carlsson, U. M., Cilio, C., Gerardsson, J., Gustavsson, B., Hansson, A., Hansson, G., Hansson, I., Ivarsson, S., Larsson, H., Karlsson, E., Katsarou, A., Lernmark, B., Massadakis, T., Nilsson, A., Järvirova, M. S., Sjöberg, B., Wallin, A., Wimar, Å., Hagopian, W. A., Brantley, M., Cowen, C., Hui, P., Hay, K. M., Jackson, M., Stepikova, V., Ugale, J., Krischer, J. P., Bray, C., Cuthbertson, D., Gowda, V., Hunt, K., Liu, S., Malloy, J., McCarthy, C., McLeod, W., Moyers, S., Nallamshetty, L., Smith, S., Akolkar, B., Briese, T., Erlich, H., Bennett Johnson, S. & Oberste, S., Oct 1 2007, In : Pediatric Diabetes. 8, 5, p. 286-298 13 p.

Research output: Contribution to journalArticle

182 Scopus citations
2008

ParaKMeans: Implementation of a parallelized K-means algorithm suitable for general laboratory use

Kraj, P., Sharma, A., Garge, N., Podolsky, R. & McIndoe, R. A., Apr 16 2008, In : BMC Bioinformatics. 9, 200.

Research output: Contribution to journalArticle

21 Scopus citations

The IL-10 and IFN-γ pathways are essential to the potent immunosuppressive activity of cultured CD8+ NKT-like cells

Zhou, L., Wang, H., Zhong, X., Jin, Y., Mi, Q. S., Sharma, A. K., McIndoe, R. A., Garge, N., Podolsky, R. & She, J-X., Jul 29 2008, In : Genome Biology. 9, 7, R119.

Research output: Contribution to journalArticle

11 Scopus citations
2009

A modified hyperplane clustering algorithm allows for efficient and accurate clustering of extremely large datasets

Sharma, A., Podolsky, R., Zhao, J. & Mcindoe, R. A., May 7 2009, In : Bioinformatics. 25, 9, p. 1152-1157 6 p.

Research output: Contribution to journalArticle

14 Scopus citations
28 Scopus citations
26 Scopus citations

Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes

Barrett, J. C., Clayton, D. G., Concannon, P., Akolkar, B., Cooper, J. D., Erlich, H. A., Julier, C., Morahan, G., Nerup, J., Nierras, C., Plagnol, V., Pociot, F., Schuilenburg, H., Smyth, D. J., Stevens, H., Todd, J. A., Walker, N. M., Rich, S. S., Baskerville, T., Bautista, N. & 380 others, Bhatia, E., Bhatia, V., Bin Hasan, K., Bonnici, F., Brodnicki, T., Cameron, F., Chaichanwatanakul, K., Cheung, P. T., Colman, P., Cotterill, A., Couper, J., Cutfield, R., Davis, T., Dixon, P., Donaghue, K., Dowling, K., Drury, P., Dye, S., Gellert, S., Abdul Ghani, R., Greer, R., Han, X., Harrison, L., Homatopoulos, N., Ji, L., Jones, T., Yin, L. K., Kamaruddin, N. A., Kanga, U., Kanungo, A., Kaur, G., Kek, B., Knowles, S., Krebs, J., Kumar, N., Lee, Y. J., Li, X., Liktimaskul, S., Lloyd, M., Loth, A., Louey, A., Mehra, N., Merriman, T., Min, L., Morahan, G., Moses, R., Mraz, G., Murphy, R., Nicholson, I., Panelo, A., Poh, P., Price, G., Ratnam, N., Sanjeevi, C., Sedimbi, S., Shen, S., Ying, G. S., Tait, B., Tandon, N., Thomas, A., Varney, M., Weerakulwattana, P., Willis, J., Albret, L., Ampudia-Blasco, F., Argente, J., Babadjanova, G., Badenhoop, K., Battelino, T., Beilhack, G., Bergholdt, R., Bingley, P., Boehm, B., Bolidson, J., Brorsson, C., Carlson, J., Castano, L., Chandler, K., Cinek, O., Cipponeri, E., Corripio, R., Garcia Cuartero, B., de Leiva, A., Fagulha, A., Fernandez Balcells, M., Guja, C., Gutierrez, P., Hatziagelaki, E., Heath, S., Helmberg, W., Hernandez, M., Holzheu, I., Hosszufalusi, N., Ionescu-Tirgoviste, C., Johannesen, J., Julier, C., Kahles, H., Knip, M., Kockum, I., Kojo, E., Koprivarova, K., Kordonouri, O., Kretowski, A., Krikovszky, D., Kurkhaus, A., Lalic, N., Lavant, E., Long, A., Ludvigsson, J., Madacsy, L., Marga, M., Mauricio, D., Mazurkievicz, G., Nerup, J., Novoa Mogollon, F. J., Petersen, M. T., Phillip, M., Pirags, V., Pociot, F., Pozzilli, P., Rappner, R., Roep, B., Rokni, S., Rosinger, S., Rubio-Cabezas, O., Ruckgaber, C., Satman, I., Schober, E., Seufert, J., Sing, R., Skrha, J., Sobngwi, E., Somerville, M., Spinas, G., Tilmann, V., Undlien, D., Urbanavicius, V., Van der Auwera, B., Vasquez San Miguel, F., Vazeo-Gerasimidi, A., Velickiene, D., Wagner, A., Williams, A., Wurzburger, M., Ziegler, A., Agleham, M., Aldrich, A., Alemzadeh, R., Aly, T., Arora, S., Austin, A., Becker, D., Benoist, C., Berka, N., Bhatia, S., Bonella, P., Bottini, N., Boyle, S., Brady, B., Brickman, W., Christensen, R., Concannon, P., Couch, R., Counts, D., Crandall, J., Daniels, M., Dolan, L., Donaldson, D., Doria, A., Eisenbarth, G., El-Hajj, R., Erlich, H., Fain, P., Fear, A. L., Ferry, R., Fiallo-Scharer, R., Ghosh, S., Gitelman, S., Godwin, M., Goland, R., Goodman, N., Goodwin, G., Gravely, J., Greenbaum, C., Gudgeon, C., Gunville, F., Hagopian, W., Hakonarson, H., Hansen, J., Harrington, K., Hassing, J., Hilliker, W., Hoffman, R., Hulbert, E., Izquierdo, R., Jospe, N., Kaiserman, K., Kaufman, F., Kim, S., Kloos, E., Kosoy, R., Lane, J., Lane, J., Lawrence, J., Levetan, C., Levin, P., Lipton, R., Lonsdale, J., Magnuson, V., Marks, J., Mayer-Davis, B., McEvoy, R., McIndoe, R. A., Merkle, L., Metzger, D., Miao, D., Mickelson, E., Moonsamy, P., Moore, W., Moran, A., Noble, J., Olsem, G., Onengut-Gumuscu, S., Orban, T., Orlowski, C., Paterson, A., Pietropaolo, M., Pihoker, C., Polychronakos, C., Post, J., Postellon, D., Pugliese, A., Qu, H., Quattrin, T., Rappaport, M., Raskin, P., Risbeck, H., Rodriguez, H., Rodriguez, L., Rogers, M., Russell, B., Schatz, D., Scott, C., She, J-X., Shulman, D., Soyka, L., Speiser, P., Starkman, H., Steck, A., Stender, S., Stratton, L., Sur, D., Taback, S., Thrailkill, K., Toth, E., Trymbiski, P., Tsalikian, E., Vertachnik, K., Wahlen, J., Wang, X., Weber, S., Wherrett, D., Willi, S., Wilson, D., Youkey, J., Young, N., Yu, L., Zimmerman, D., Adlem, E., Allen, J., Brown, J., Burren, O., Clarke, P., Clayton, D., Coleman, G., Cooper, J., Cucca, F., Duley, S., Dunger, D., Everett, V., Hardy, M., Harrison, D., Harrison, I., Hawkins, S., Healy, B., Hood, S., Howell, S., Maisuria, M., Meadows, W., Mistry, T., Nutland, S., Ovington, N., Schuilenburg, H., Simpson, A., Smink, L., Stevens, H., Taylor, N., Todd, J., Tuomilehto, J., Walker, N., Widmer, B., Wilson, M., Withers, H., Brown, M., Chen, W. M., Crews, A., Griffin, J., Hall, M., Harnish, T., Hepler, J., Hilner, J., King, N., Lohman, K., Lu, L., Mychaleckyj, J., Nail, J., Perdue, L., Pierce, J., Reboussin, D., Rich, S., Rushing, S., Sale, M., Sides, E., Snively, B., Teuschler, H., Theil, G., Williams, D., Akolkar, B., McKeon, C., Nierras, C., Thomson, E., Altshuler, D., Au, K., Bain, S., Barcellos, L., Barral, S., Becker, T., Briggs, F., Bronson, P., Daly, M., de Bakker, P., Deloukas, P., Devlin, B., Eike, M. C., Field, L., Gabriel, S., Garge, N., Gaudieri, S., Goldstein, B., Gorodezky, C., Hamon, S., He, C., Howson, J., Humphreys, K., James, I., Lathrop, M., Lie, B. A., Li, D., Mack, S., McGinnis, R., McKinnon, E., McLaren, W., Nolan, D., Olsson, M., Ott, J., Owerbach, D., Patterson, C., Podolsky, R., Ramsay, P., Rangantah, V., Risch, N., Ronningen, K. S., Shao, X., Single, R., Steffes, M., Thomson, G., Valdes, A. M., Vandiedonck, C., Whittaker, P. & Zhang, Q., Jun 1 2009, In : Nature Genetics. 41, 6, p. 703-707 5 p.

Research output: Contribution to journalArticle

1096 Scopus citations
2010
13 Scopus citations

Hepatic gene expression profiling reveals key pathways involved in leptin-mediated weight loss in ob/ob mice

Sharma, A., Bartell, S. M., Baile, C. A., Chen, B., Podolsky, R. H., McIndoe, R. A. & She, J. X., 2010, In : PloS one. 5, 8, e12147.

Research output: Contribution to journalArticle

19 Scopus citations

Para SAM: A parallelized version of the significance analysis of microarrays algorithm

Sharma, A. K., Zhao, J., Podolsky, R. & McIndoe, R. A., Apr 15 2010, In : Bioinformatics. 26, 11, p. 1465-1467 3 p., btq161.

Research output: Contribution to journalArticle

1 Scopus citations
2011
9 Scopus citations
2012

Differences in recruitment and early retention among ethnic minority participants in a large pediatric cohort: The TEDDY Study

Baxter, J., Vehik, K., Johnson, S. B., Lernmark, B., Roth, R., Simell, T., Rewers, M., Barriga, K., Bautista, K., Baxter, J., Eisenbarth, G., Frank, N., Gesualdo, P., Hoffman, M., Ide, L., Karban, R., Liu, E., Norris, J., Waugh, K., Samper-Imaz, A. & 149 others, Steck, A., She, J-X., Schatz, D., Hopkins, D., Steed, L., Thomas, J., Silvis, K., Haller, M., Shankar, M., English, K., McIndoe, R. A., Liu, H., Nechtman, J., Williams, J., Foghis, G., Stephen, W., Anderson, M. D., Ziegler, A. G., Achenbach, A., Boerschmann, H., Bonifacio, E., Bunk, M., Försch, J., Henneberger, L., Hummel, M., Hummel, S., Joslowski, G., Kersting, M., Knopff, A., Kocher, N., Koletzko, S., Krause, S., Mann, A., Matzke, C., Mittermeier, A., Peplow, C., Pflüger, M., Ramminger, C., Strauss, E., Rash-Sur, S., Roth, R., Schenkel, J., Stock, J., Voit, K., Winkler, C., Wosch, A., Zwilling, M., Simell, O. G., Nanto-Salonen, K., Ilonen, J., Knip, M., Tuula Simell, V., Hyöty, H., Virtanen, S. M., Kronberg-Kippilä, C., Sjöberg, M., Simell, B., Ruohonen, E., Romo, M., Mantymaki, E., Schroderus, H., Nyblom, M., Stenius, A., Lernmark, Å., Agardh, D., Almgren, P., Andersson, E., Andrén-Aronsson, C., Ask, M., Karlsson, U. M., Cilio, C., Bremer, J., Ericson-Hallström, E., Gard, T., Gerardsson, J., Hansson, G., Hansen, M., Hyberg, S., Håkansson, R., Johansen, F., Jonsson, L., Larsson, H., Lernmark, B., Markan, M., Massadakis, T., Melin, J., Månsson-Martinez, M., Nilsson, A., Rahmati, K., Järvirova, M. S., Sibthorpe, S., Sjöberg, B., Skogberg, A., Törn, C., Wallin, A., Wimar, Å., Åberg, S., Hagopian, W. A., Yan, X., Killian, M., Cowen Crouch, C., Hay, K. M., Ayres, S., Adams, C., Bratrude, B., Coughlin, D., Fowler, G., Franco, C., Hammar, C., Heaney, D., Marcus, P., Meyer, A., Mulenga, D., Scott, E., Skidmore, J., Stabbert, J., Stepitova, V., Williams, N., Becker, D., Franciscus, M., Dalmagro-Elias, M. E., Daftary, A., Krischer, J. P., Abbondondolo, M., Ballard, L., Brown, R., Burkhardt, B., Cuthbertson, D., Eberhard, C., Fiske, S., Gowda, V., Hadley, D., Lee, H. S., Liu, S., Lynch, K., Malloy, J., McCarthy, C., McLeod, W., Smith, L., Smith, S., Uusitalo, U., Vehik, K., Washington, E., Yang, J., Akolkar, B., Briese, T., Erlich, H., Johnson, S. B. & Oberste, S., Jul 2012, In : Contemporary Clinical Trials. 33, 4, p. 633-640 8 p.

Research output: Contribution to journalArticle

25 Scopus citations

Research resource: DkCOIN, the National Institute of Diabetes, Digestive and Kidney Diseases (NIDDK) Consortium Interconnectivity Network: A pilot program to aggregate research resources generated by multiple research consortia

McKenna, N. J., Howard, C. L., Aufiero, M., Easton-Marks, J., Steffen, D. L., Becnel, L. B., Magnuson, M. A., McIndoe, R. A. & Cartailler, J. P., Oct 1 2012, In : Molecular Endocrinology. 26, 10, p. 1675-1681 7 p.

Research output: Contribution to journalArticle

2 Scopus citations
2013

Thymus-derived regulatory T cells contribute to tolerance to commensal microbiota

Cebula, A., Seweryn, M., Rempala, G. A., Pabla, S. S., McIndoe, R. A., Denning, T. L., Bry, L., Kraj, P., Kisielow, P. & Ignatowicz, L., Apr 29 2013, In : Nature. 497, 7448, p. 258-262 5 p.

Research output: Contribution to journalArticle

207 Scopus citations
2014

Biomarker discovery study design for type 1 diabetes in The Environmental Determinants of Diabetes in the Young (TEDDY) study

Lee, H. S., Burkhardt, B. R., Mcleod, W., Smith, S., Eberhard, C., Lynch, K., Hadley, D., Rewers, M., Simell, O., She, J. X., Hagopian, B., Lernmark, A., Akolkar, B., Ziegler, A. G., Krischer, J. P., Barriga, K., Bautista, K., Baxter, J., Eisenbarth, G., Frank, N. & 208 others, Gesualdo, P., Hoffman, M., Ide, L., Karban, R., Liu, E., Norris, J., Waugh, K., Samper-Imaz, A., Steck, A., Schatz, D., Hopkins, D., Steed, L., Thomas, J., Silvis, K., Haller, M., Shankar, M., Sheehan, E., Gardiner, M., McIndoe, R., Liu, H., Nechtman, J., Sharma, A., Williams, J., Foghis, G., Anderson W., S. W., Beyerlein, A., Bonifacio, E., Hummel, M., Hummel, S., Foterek, K., Kersting, M., Knopff, A., Koletzko, S., Peplow, C., Roth, R., Schenke, J., Stock, J., Strauss, E., Warncke, K., Winkler, C., Simell G., O. G., Hyoty, H., Ilonen, J., Knip, M., Koivu, A., Koreasalo, M., Kahonen, M., Lonnrot, M., Multasuo, K., Mantymaki, E., Mykkanen, J., Nanto-Salonen, K., Niininen, T., Nyblom, M., Rautanen, J., Riikonen, A., Romo, M., Simell, A., Simell, B., Simell, T., Simell, V., Sjoberg, M., Stenius, A., Toppari, J., Varjonen, E., Veijola, R., Virtanen M., S. M., Akerlund, M., Agardh, D., Andrén-Aronsson, C., Ask, M., Bremer, J., Carlsson, U. M., Cilio, C., Ericson-Hallstrom, E., Fransson, L., Gard, T., Gerardsson, J., Hakansson, R., Hansen, M., Hansson, G., Hyberg, S., Johansen, F., Jonasdottir, B., Jonsson, L., Larsson, H., Lernmark, B., Mansson-Martinez, M., Markan, M., Massadakis, T., Melin, J., Mestan, Z., Nilsson, A., Nilsson, E., Rahmati, K., Rosenquist, A., Salami, F., Jarvirova, M. S., Sibthorpe, S., Sjoberg, B., Swartling, U., Trulsson, E., Torn, C., Wallin, A., Wimar, A., Aberg, S., Hagopian A., W. A., Yan, X., Killian, M., Crouch, C. C., Hay M., K. M., Ayres, S., Adams, C., Bratrude, B., Coughlin, D., Fowler, G., Franco, C., Hammar, C., Heaney, D., Marcus, P., Meyer, A., Mulenga, D., Scott, E., Skidmore, J., Stabbert, J., Stepitova, V., Williams, N., Becker, D., Franciscus, M., Dalmagro-Elias, M. E., Daftary, A., Klein, M. B., Abbondondolo, M., Austin-Gonzalez, S., Brown, R., Burkhardt, B., Butterworth, M., Cuthbertson, D., Eberhard, C., Fiske, S., Gowda, V., Lane, P., Liu, S., Liu, X., Malloy, J., McCarthy, C., McLeod, W., Smith, L., Tamura, R., Uusitalo, U., Vehik, K., Washington, E., Yang, J., Bourcier, K., Briese, T., Johnson, S. B., Oberste, S., Triplett, E., Yu, L., Miao, D., Bingley, P., Williams, A., Chandler, K., Rokni, S., Long, A., Boldison, J., Butterly, J., Broadhurst, J., Carreno, G., Curnock, R., Easton, P., Geoghan, I., Goode, J., Pearson, J., Reed, C., Ridewood, S., Wyatt, R., Eriksson, E. A., Karlsson, E. L., Erlund, I., Salminen, I., Sundvall, J., Leiviska, J., Lehtonen, M., Little R., R. R., Tennill L., A. L., Erlich, H., Bugawan, T., Alejandrino, M., Fiehn, O., Wikoff, B., Kind, T., Palazoglu, M., Wong, J., Wohlgemuth, G., Petrosino F., J. F., Marcovina M., S. M., Higgins, H., Ke, S., Zhao, Y., Jiang, N., Rich S., S. S., Chen, W. M., Onengut-Gumuscu, S., Farber, E., Pickin, R. R., Davis, J. & Gallo, D., Jul 2014, In : Diabetes/Metabolism Research and Reviews. 30, 5, p. 424-434 11 p.

Research output: Contribution to journalArticle

17 Scopus citations

The same self-peptide selects conventional and regulatory CD4 + T cells with identical antigen receptors

Wojciech, L., Ignatowicz, A., Seweryn, M., Rempala, G., Singh Pabla, S., McIndoe, R. A., Kisielow, P. & Ignatowicz, L., 2014, In : Nature communications. 5, 5061.

Research output: Contribution to journalArticle

14 Scopus citations
2015

Fine mapping of type 1 diabetes susceptibility loci and evidence for colocalization of causal variants with lymphoid gene enhancers

Onengut-Gumuscu, S., Chen, W. M., Burren, O., Cooper, N. J., Quinlan, A. R., Mychaleckyj, J. C., Farber, E., Bonnie, J. K., Szpak, M., Schofield, E., Achuthan, P., Guo, H., Fortune, M. D., Stevens, H., Walker, N. M., Ward, L. D., Kundaje, A., Kellis, M., Daly, M. J., Barrett, J. C. & 419 others, Cooper, J. D., Deloukas, P., Todd, J. A., Wallace, C., Concannon, P., Rich, S. S., Baskerville, T., Bautista, N., Bhatia, E., Bhatia, V., Hasan, K. B., Bonnici, F., Brodnicki, T., Browning, B., Cameron, F., Chaichanwatanakul, K., Cheung, P. T., Colman, P., Cotterill, A., Couper, J., Crock, P., Cutfield, R., Davis, T., Dixon, P., Donaghue, K., Dowling, K., Drury, P., Dye, S., Gellert, S., Ghani, R. A., Greer, R., Han, X., Harrison, L., Homatopoulos, N., Ji, L., Jones, T., Yin, L. K., Kamaruddin, N. A., Kanga, U., Kanungo, A., Kaur, G., Kek, B., Knowles, S., Krebs, J., Kumar, N., Lee, Y. J., Li, X., Liktimaskul, S., Lloyd, M., Loth, A., Louey, A., Mehra, N., Merriman, T., Min, L., Morahan, G., Moses, R., Mraz, G., Murphy, R., Nicholson, I., Panelo, A., Poh, P., Price, G., Ratnam, N., Sanjeevi, C., Sedimbi, S., Shen, S., Ying, G. S., Tait, B., Tandon, N., Thomas, A., Varney, M., Weerakulwattana, P., Willis, J., Akwo, E. A., Albret, L., Ampudia-Blasco, F., Argente, J., Avbelj, M., Babadjanova, G., Badenhoop, K., Battelino, T., Beilhack, G., Bergholdt, R., Bingley, P., Boehm, B., Bolidson, J., Brismar, K., Brorsson, C., Carlson, J., Castano, L., Chandler, K., Cherubini, V., Cinek, O., Cipponeri, E., Collado, R. C., de Leiva, A., Dzivite, I., Fagulha, A., Balcells, M. F., Cuartero, B. G., Lacalle, C. G., Guja, C., Gutiérrez, P., Hamou, A., Hatziagelaki, E., Heath, S., Heilman, K., Helmberg, W., Hermon, O., Hernandez, M., Holzheu, I., Hosszufalusi, N., Ilonen, J., Ionescu-Tirgoviste, C., Johannesen, J., Julier, C., Kahles, H., Kinalska, I., Knip, M., Kockum, I., Kojo, E., Kordonouri, O., Kretowski, A., Krikovszky, D., Kurkhaus, A., Kuzmicki, M., Lavant, E., Long, A., Ludvigsson, J., Madacsy, L., Maliszewska, K., Marga, M., Martinez, M. P., Mauricio, D., Mazurkievicz, G., Nerup, J., Norkus, A., Mogollon, F. J. N., Okruszko, A., Pettinari, C., Phillip, M., Pirags, V., Pociot, F., Pozzilli, P., Racasan, R., Raile, K., Rappner, R., Troyano, M. J. R., Roep, B. O., Rokni, S., Rosinger, S., Rubio-Cabezas, O., Ruckgaber, C., Satman, I., Schober, E., Seufert, J., Sing, R., Skrha, J., Sobngwi, E., Somerville, M., Spinas, G., Sumnik, Z., Tilmann, V., Undlien, D., Urbanavicius, V., der Auwera, B. V., San Miguel, F. V., Vazeo-Gerasimidi, A., Velickiene, D., Wägner, A., Walter, M., Williams, A., Ziegler, A., Agleham, M., Aldrich, A., Alemzadeh, R., Alper, C., Aly, T., Anastassiou, D., Arora, S., Austin, A., Becker, D., Benoist, C., Berka, N., Bhatia, S., Bonella, P., Bottini, N., Boyle, S., Braden, J., Brady, B., Brickman, W., Christensen, R., Couch, R., Counts, D., Crandall, J., Daniels, M., Dolan, L., Donaldson, D., Doria, A., Eisenbarth, G., Elder, J., El-Hajj, R., Erlich, H., Fain, P., Fear, A. L., Ferry, R., Fiallo-Scharer, R., Geraghty, D., Ghosh, S., Gitelman, S., Godwin, M., Goland, R., Goodman, N., Goodwin, G., Gravely, J., Greenbaum, C., Gudgeon, C., Gunville, F., Hagopian, W., Hakonarson, H., Hansen, J., Harrington, K., Hassing, J., Hilliker, W., Hoffman, R., Hulbert, E., Izquierdo, R., Jospe, N., Kaiserman, K., Kaufman, F., Kim, S., Kloos, E., Kosoy, R., Lane, J., Lane, J., Lawrence, J., Levetan, C., Levin, P., Lipton, R., Lonsdale, J., Magnuson, V., Marks, J., Mayer-Davis, B., McEvoy, R., McIndoe, R., Merkle, L., Metzger, D., Miao, D., Mickelson, E., Moonsamy, P., Moore, W., Moran, A., Noble, J., Olsem, G., Orban, T., Orlowski, C., Paterson, A., Pietropaolo, M., Pihoker, C., Polychronakos, C., Post, J., Postellon, D., Pugliese, A., Qu, H. Q., Quattrin, T., Rappaport, M., Raskin, P., Risbeck, H., Rodriguez, H., Rodriguez, L., Rogers, M., Rubalcava, L., Russell, B., Schatz, D., Scott, C., She, J. X., Shilling, H., Shulman, D., Soyka, L., Speiser, P., Starkman, H., Steck, A., Stender, S., Stratton, L., Sur, D., Taback, S., Thrailkill, K., Toth, E., Trymbiski, P., Tsalikian, E., Vertachnik, K., Wahlen, J., Wang, X., Weber, S., Wherrett, D., Willi, S., Wilson, D., Youkey, J., Young, N., Yu, L., Zhao, L. P., Zimmerman, D., Adlem, E., Allen, J., Brown, J., Clarke, P., Clayton, D., Coleman, G., Cucca, F., Davison, L., Downes, K., Duley, S., Dunger, D., Esposito, L., Everett, V., Field, S., Hafler, J., Hardy, M., Harrison, D., Harrison, I., Hawkins, S., Healy, B., Hood, S., Howell, S., Howson, J., Maisuria, M., Meadows, W., Mistry, T., Nezhenstsev, S., Nutland, S., Ovington, N., Plagnol, V., Rainbow, D., Rainbow, K., Raj, S., Schuilenburg, H., Simpson, A., Smink, L., Smyth, D., Taylor, N., Tuomilehto, J., Wicker, L., Widmer, B., Wilson, M., Withers, H., Yang, J., Brown, M., Crews, A., Griffin, J., Hall, M., Harnish, T., Hepler, J., Hilner, J., King, N., Lohman, K., Lu, L., Nail, J., Perdue, L., Pierce, J., Reboussin, D., Rushing, S., Sale, M., Sides, E., Snively, B., Teuschler, H., Theil, G., Wagenknecht, L., Williams, D., Akolkar, B., McKeon, C., Nierras, C., Thomson, E., Altshuler, D., Au, K., Bain, S., Barcellos, L., Barral, S., Becker, T., Briggs, F., Bronson, P., de Bakker, P., Devlin, B., Eike, M. C., Field, L., Gabriel, S., Garge, N., Gaudieri, S., Goldstein, B., Gorodezky, C., Hamon, S., He, C., Howson, J., Humphreys, K., James, I., Lathrop, M., Lie, B. A., Li, D., Mack, S., McGinnis, R., McKinnon, E., McLaren, W., Nolan, D., Olsson, M., Ott, J., Owerbach, D., Patterson, C., Podolsky, R., Ramsay, P., Rangantah, V., Risch, N., Ronningen, K. S., Shao, X., Single, R., Steffes, M., Thomson, G., Valdes, A. M., Vandiedonck, C., Whittaker, P. & Zhang, Q., Apr 28 2015, In : Nature Genetics. 47, 4, p. 381-386 6 p.

Research output: Contribution to journalArticle

240 Scopus citations

Maternal anxiety about a child's diabetes risk in the TEDDY study: The potential role of life stress, postpartum depression, and risk perception

TEDDY study group, Jun 1 2015, In : Pediatric Diabetes. 16, 4, p. 287-298 12 p.

Research output: Contribution to journalArticle

11 Scopus citations
2016
6 Scopus citations

Association of Early Exposure of Probiotics and Islet Autoimmunity in the TEDDY Study

Dietary Biomarkers Laboratory, Project Scientist, Other contributors, Autoantibody Reference Laboratories, Cortisol Laboratory, Data Coordinating Center, Pennsylvania Satellite Center, Washington Clinical Center, Sweden Clinical Center, Finland Clinical Center, Germany Clinical Center, Georgia/Florida Clinical Center, for the TEDDY Study Group, SNP Laboratory, RNA Laboratory and Gene Expression Laboratory, Microbiome and Viral Metagenomics Laboratory, Metabolomics Laboratory, HbA1c Laboratory, HLA Reference Laboratory, OGTT Laboratory & 2 others, Proteomics Laboratory & Repository, Jan 2016, In : JAMA Pediatrics. 170, 1, p. 20-28 9 p.

Research output: Contribution to journalArticle

101 Scopus citations
2017

Analgesic antipyretic use among young children in the TEDDY study: No association with islet autoimmunity

for the TEDDY Study Group, May 16 2017, In : BMC pediatrics. 17, 1, 127.

Research output: Contribution to journalArticle

7 Scopus citations

Association between early-life antibiotic use and the risk of islet or celiac disease autoimmunity

Kemppainen, K. M., Vehik, K., Lynch, K. F., Larsson, H. E., Canepa, R. J., Simell, V., Koletzko, S., Liu, E., Simell, O. G., Toppari, J., Ziegler, A. G., Rewers, M. J., Lernmark, Å., Hagopian, W. A., She, J-X., Akolkar, B., Schatz, D. A., Atkinson, M. A., Blaser, M. J., Krischer, J. P. & 185 others, Hyöty, H., Agardh, D., Triplett, E. W., Bautista, K., Baxter, J., Bedoy, R., Felipe-Morales, D., Driscoll, K., Frohnert, B. I., Gesualdo, P., Hoffman, M., Karban, R., Norris, J., Samper-Imaz, A., Steck, A., Waugh, K., Wright, H., Adamsson, A., Ahonen, S., Ilonen, J., Jokipuu, S., Kallio, T., Karlsson, L., Kähönen, M., Knip, M., Kovanen, L., Koreasalo, M., Kurppa, K., Latva-Aho, T., Lönnrot, M., Mäntymäki, E., Multasuo, K., Mykkänen, J., Niininen, T., Niinistö, S., Nyblom, M., Rajala, P., Rautanen, J., Riikonen, A., Riikonen, M., Rouhiainen, J., Romo, M., Simell, T., Sjöberg, M., Stenius, A., Leppänen, M., Vainionpää, S., Varjonen, E., Veijola, R., Virtanen, S. M., Vähä-Mäkilä, M., Åkerlund, M., Lindfors, K., Schatz, D., Hopkins, D., Steed, L., Thomas, J., Adams, J., Silvis, K., Haller, M., Gardiner, M., McIndoe, R. A., Sharma, A. K., William, J., Young, G., Anderson, S. W., Jacobsen, L., Beyerlein, A., Bonifacio, E., Hummel, M., Hummel, S., Foterek, K., Janz, N., Kersting, M., Knopff, A., Peplow, C., Roth, R., Scholz, M., Stock, J., Warncke, K., Wendel, L., Winkler, C., Aronsson, C. A., Ask, M., Bremer, J., Carlsson, U. M., Cilio, C., Ericson-Hallström, E., Fransson, L., Gard, T., Gerardsson, J., Bennet, R., Hansen, M., Hansson, G., Hyberg, S., Johansen, F., Jonsdottir, B., Lindström, M., Lundgren, M., Månsson-Martinez, M., Markan, M., Melin, J., Mestan, Z., Ottosson, K., Rahmati, K., Ramelius, A., Salami, F., Sibthorpe, S., Sjöberg, B., Swartling, U., Amboh, E. T., Törn, C., Wallin, A., Wimar, Å., Åberg, S., Killian, M., Crouch, C. C., Skidmore, J., Carson, J., Dalzell, M., Dunson, K., Hervey, R., Johnson, C., Lyons, R., Meyer, A., Mulenga, D., Tarr, A., Uland, M., Willis, J., Becker, D., Franciscus, M., Smith, M. E. D. E., Daftary, A., Klein, M. B., Yates, C., Abbondondolo, M., Austin-Gonzalez, S., Avendano, M., Baethke, S., Brown, R., Burkhardt, B., Butterworth, M., Clasen, J., Cuthbertson, D., Eberhard, C., Fiske, S., Garcia, D., Garmeson, J., Gowda, V., Heyman, K., Laras, F. P., Lee, H. S., Liu, S., Liu, X., Lynch, K., Malloy, J., McCarthy, C., Meulemans, S., Parikh, H., Shaffer, C., Smith, L., Smith, S., Sulman, N., Tamura, R., Uusitalo, U., Vijayakandipan, P., Wood, K., Yang, J., Ballard, L., Hadley, D., McLeod, W., Bourcier, K., Briese, T., Johnson, S. B., Yu, L., Miao, D., Bingley, P., William's, A., Chandler, K., Rokni, S., Willia, C., Wyatt, R., George, G., Grace, S. & Mulholland, N., Dec 2017, In : JAMA Pediatrics. 171, 12, p. 1217-1225 9 p.

Research output: Contribution to journalArticle

29 Scopus citations